Homo sapiens

18 known processes

SPPL2B

signal peptide peptidase-like 2B

(Aliases: PSL1,KIAA1532,MGC111084,IMP4)

SPPL2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.093
ribonucleoside catabolic processGO:00424544060.070
positive regulation of phosphorylationGO:00423273940.055
purine ribonucleoside triphosphate metabolic processGO:00092054110.051
small gtpase mediated signal transductionGO:0007264780.049
ras protein signal transductionGO:0007265730.049
rab protein signal transductionGO:003248240.048
vesicle mediated transportGO:00161923710.047
purine ribonucleoside catabolic processGO:00461303980.046
determination of adult lifespanGO:000834020.044
nucleoside phosphate catabolic processGO:19012924120.044
multicellular organismal agingGO:001025930.044
female gamete generationGO:000729220.043
signal transduction by phosphorylationGO:00230142970.042
regulation of purine nucleotide metabolic processGO:19005422640.042
purine nucleoside triphosphate metabolic processGO:00091444120.040
purine nucleoside triphosphate catabolic processGO:00091463920.039
oogenesisGO:004847720.038
anion transportGO:00068201610.037
cellular ketone metabolic processGO:0042180800.037
cellular amino acid metabolic processGO:00065201160.037
regulation of cell cycleGO:00517263930.037
monocarboxylic acid metabolic processGO:00327871850.036
purine ribonucleoside metabolic processGO:00461284370.034
purine containing compound catabolic processGO:00725234110.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
endosomal transportGO:00161971290.033
organonitrogen compound biosynthetic processGO:19015662000.033
neuromuscular junction developmentGO:000752830.033
nucleotide catabolic processGO:00091664080.033
positive regulation of nucleotide metabolic processGO:00459812300.032
cytoplasmic transportGO:00164823790.032
amine metabolic processGO:0009308440.031
nucleoside catabolic processGO:00091644080.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
regulation of gtpase activityGO:00430871800.031
response to oxygen containing compoundGO:19017003690.031
ribonucleotide catabolic processGO:00092614050.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
regulation of transferase activityGO:00513383550.030
regulation of mapk cascadeGO:00434082620.030
dermatan sulfate metabolic processGO:003020530.030
organophosphate catabolic processGO:00464344300.030
cell morphogenesisGO:00009022960.029
negative regulation of developmental processGO:00510932470.029
positive regulation of cellular catabolic processGO:00313312840.029
segmentationGO:003528240.029
negative regulation of catalytic activityGO:00430863350.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
regulation of cellular amino acid metabolic processGO:000652160.028
purine nucleoside catabolic processGO:00061523980.028
positive regulation of cellular component organizationGO:00511303760.028
regulation of nucleotide catabolic processGO:00308112050.028
guanosine containing compound catabolic processGO:19010692390.028
intracellular protein transportGO:00068862700.028
cell projection organizationGO:00300302520.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
mapk cascadeGO:00001652880.028
regulation of purine nucleotide catabolic processGO:00331212050.027
guanosine containing compound metabolic processGO:19010682440.027
organic anion transportGO:00157111030.027
anterior posterior axis specificationGO:000994820.027
purine nucleotide catabolic processGO:00061954050.026
cellular lipid metabolic processGO:00442553030.026
negative regulation of phosphate metabolic processGO:00459362670.026
regulation of protein kinase activityGO:00458592890.025
glycosyl compound catabolic processGO:19016584130.025
cellular macromolecular complex assemblyGO:00346223240.025
positive regulation of nucleotide catabolic processGO:00308131850.025
regulation of kinase activityGO:00435493140.025
purine ribonucleotide catabolic processGO:00091544040.025
lipid metabolic processGO:00066293810.024
regulation of cellular amine metabolic processGO:0033238110.024
mitotic cell cycleGO:00002783260.024
regulation of cellular component biogenesisGO:00440872810.024
positive regulation of catabolic processGO:00098963100.023
positive regulation of transportGO:00510503360.023
positive regulation of cellular amine metabolic processGO:003324070.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
protein modification by small protein conjugationGO:00324463420.023
cellular amine metabolic processGO:0044106410.023
chemical homeostasisGO:00488783060.023
regulation of cellular ketone metabolic processGO:0010565500.022
cell fate determinationGO:000170930.022
positive regulation of hydrolase activityGO:00513453310.022
nucleoside triphosphate catabolic processGO:00091433940.022
response to abiotic stimulusGO:00096283360.022
protein localization to organelleGO:00333652800.021
regulation of cell migrationGO:00303342890.021
positive regulation of protein kinase activityGO:00458601900.021
transmembrane transportGO:00550853990.021
positive regulation of transferase activityGO:00513472270.021
cellular response to oxygen containing compoundGO:19017012760.020
nucleoside triphosphate metabolic processGO:00091414220.020
positive regulation of protein phosphorylationGO:00019343130.020
negative regulation of hydrolase activityGO:00513461820.020
regulation of protein serine threonine kinase activityGO:00719001790.020
negative regulation of cellular component organizationGO:00511292350.020
regulation of locomotionGO:00400123290.020
regenerationGO:003109940.020
rho protein signal transductionGO:0007266260.020
regulation of proteolysisGO:00301622930.020
positive regulation of nucleoside metabolic processGO:00459791860.020
tripartite regional subdivisionGO:000735120.020
oocyte developmentGO:004859910.019
regulation of cell cycle processGO:00105642660.019
covalent chromatin modificationGO:00165692540.019
gtp catabolic processGO:00061842370.019
regulation of gtp catabolic processGO:00331241800.019
protein ubiquitinationGO:00165673140.019
actin filament based processGO:00300292240.019
regulation of nucleoside metabolic processGO:00091182090.019
nitrogen compound transportGO:00717051910.018
regulation of ras protein signal transductionGO:00465781550.018
protein localization to membraneGO:00726571600.018
blastoderm segmentationGO:000735020.018
cation transportGO:00068123310.018
cell adhesionGO:00071553250.018
carbohydrate metabolic processGO:00059752070.018
anterior posterior axis specification embryoGO:000859520.018
growthGO:00400072020.018
mitochondrion organizationGO:00070051560.018
cellular cation homeostasisGO:00300031630.018
chromatin organizationGO:00063253510.018
cellular macromolecule catabolic processGO:00442653800.018
immune responseGO:00069553070.018
negative regulation of phosphorus metabolic processGO:00105632670.018
single organism cellular localizationGO:19025803320.018
cation homeostasisGO:00550801890.018
regulation of cellular response to stressGO:00801352440.018
regulation of small gtpase mediated signal transductionGO:00510561560.017
negative regulation of programmed cell deathGO:00430693210.017
ion homeostasisGO:00508012300.017
lipid transportGO:0006869900.017
spermatid differentiationGO:004851540.017
positive regulation of cell deathGO:00109422630.017
organophosphate biosynthetic processGO:00904071630.017
cell developmentGO:00484683280.017
negative regulation of cellular protein metabolic processGO:00322693530.017
memoryGO:000761330.017
oocyte differentiationGO:000999420.017
protein targetingGO:00066051870.017
lipid biosynthetic processGO:00086101770.017
regulation of anatomical structure morphogenesisGO:00226032860.017
dephosphorylationGO:00163112090.017
positive regulation of gtp catabolic processGO:00331261660.016
maintenance of locationGO:00512351120.016
negative regulation of multicellular organismal processGO:00512413170.016
neuroblast proliferationGO:000740540.016
system processGO:00030083490.016
mitotic cell cycle processGO:19030472860.016
cellular protein catabolic processGO:00442572610.016
positive regulation of rab gtpase activityGO:0032851390.016
single organism carbohydrate metabolic processGO:00447231930.016
metal ion transportGO:00300012720.016
locomotory behaviorGO:000762610.016
regulation of response to external stimulusGO:00321012220.016
positive regulation of apoptotic processGO:00430652460.016
protein localization to plasma membraneGO:0072659930.016
sulfur compound metabolic processGO:00067901010.016
negative regulation of transportGO:00510511760.016
negative regulation of cell deathGO:00605483450.015
cellular protein complex assemblyGO:00436231880.015
histone modificationGO:00165702510.015
positive regulation of protein serine threonine kinase activityGO:00719021190.015
plasma membrane organizationGO:00070091150.015
endomembrane system organizationGO:00102561960.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
positive regulation of developmental processGO:00510943140.015
spermatid developmentGO:000728640.015
regulation of vesicle mediated transportGO:00606271300.015
secretion by cellGO:00329402260.015
positive regulation of kinase activityGO:00336742040.015
carboxylic acid catabolic processGO:0046395710.015
regulation of mitotic cell cycleGO:00073461890.015
positive regulation of immune system processGO:00026842830.015
regulation of protein transportGO:00512232130.015
lipid localizationGO:00108761060.015
small molecule catabolic processGO:0044282920.015
secretionGO:00469032540.014
negative regulation of protein metabolic processGO:00512483910.014
single organism membrane organizationGO:00448022680.014
organelle assemblyGO:00709251760.014
divalent inorganic cation homeostasisGO:00725071360.014
gtp metabolic processGO:00460392390.014
protein oligomerizationGO:00512591730.014
nuclear transportGO:00511691790.014
regulation of protein localizationGO:00328802960.014
endocytosisGO:00068971590.014
reactive nitrogen species metabolic processGO:200105730.014
peripheral nervous system developmentGO:000742220.014
positive regulation of programmed cell deathGO:00430682490.014
apoptotic signaling pathwayGO:00971902680.014
cell part morphogenesisGO:00329901370.014
atp metabolic processGO:00460341760.014
positive regulation of mapk cascadeGO:00434101900.014
regulation of ras gtpase activityGO:00323181280.014
regulation of nucleotide metabolic processGO:00061402690.014
nervous system developmentGO:00073992930.014
ion transmembrane transportGO:00342203380.014
cellular response to dna damage stimulusGO:00069743790.014
biological adhesionGO:00226103310.014
negative regulation of intracellular signal transductionGO:19025321830.014
regulation of protein catabolic processGO:00421761550.014
peptidyl tyrosine phosphorylationGO:00181081700.013
regulation of establishment of protein localizationGO:00702012420.013
regulation of synaptic plasticityGO:004816730.013
membrane organizationGO:00610242920.013
cellular chemical homeostasisGO:00550821800.013
morphogenesis of embryonic epitheliumGO:001633140.013
regulation of cellular component movementGO:00512703340.013
response to cytokineGO:00340972320.013
cellular component morphogenesisGO:00329893140.013
glycoprotein metabolic processGO:00091001100.013
regulation of cell differentiationGO:00455953930.013
negative regulation of cellular amine metabolic processGO:003323930.013
inorganic ion transmembrane transportGO:00986602310.013
protein catabolic processGO:00301633250.013
regulation of intracellular protein transportGO:00331571230.013
neurogenesisGO:00220081690.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of cell divisionGO:00513021160.013
positive regulation of organelle organizationGO:00106381950.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of rab protein signal transductionGO:0032483390.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
syncytium formation by plasma membrane fusionGO:000076820.013
mitotic cell cycle phase transitionGO:00447721620.013
regulation of rab gtpase activityGO:0032313390.013
negative regulation of synaptic transmissionGO:005080520.013
neurological system processGO:00508771630.013
microtubule cytoskeleton organizationGO:00002261760.013
innate immune responseGO:00450871780.013
regulation of growthGO:00400081650.013
regulation of cell motilityGO:20001452990.013
cellular homeostasisGO:00197251960.013
compound eye developmentGO:004874910.013
regulation of hormone levelsGO:00108171250.013
nucleoside monophosphate metabolic processGO:00091231910.012
cell growthGO:00160491600.012
establishment of protein localization to membraneGO:00901501210.012
regulation of cell growthGO:00015581350.012
positive regulation of ras gtpase activityGO:00323201170.012
regulation of secretionGO:00510461940.012
positive regulation of cell differentiationGO:00455972110.012
myoblast fusionGO:000752010.012
positive regulation of locomotionGO:00400171860.012
cilium assemblyGO:0042384630.012
protein maturationGO:00516042330.012
rna processingGO:00063962550.012
response to nitrogen compoundGO:19016981840.012
cation transmembrane transportGO:00986552380.012
positive regulation of cell migrationGO:00303351720.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
i kappab kinase nf kappab signalingGO:00072491660.012
cell cycle phase transitionGO:00447701730.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
metal ion homeostasisGO:00550651690.012
positive regulation of cell proliferationGO:00082843010.012
regulation of intracellular transportGO:00323861950.012
regulation of immune responseGO:00507762010.012
regulation of protein maturationGO:19033171500.012
regulation of apoptotic signaling pathwayGO:20012331750.012
reactive oxygen species biosynthetic processGO:190340940.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
epithelial cell migrationGO:00106311190.012
negative regulation of apoptotic processGO:00430663160.012
cellular carbohydrate metabolic processGO:0044262840.012
glycerolipid metabolic processGO:00464861070.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
cell type specific apoptotic processGO:00972851250.011
carbohydrate derivative biosynthetic processGO:19011372070.011
mitotic nuclear divisionGO:00070671190.011
regulation of meiotic cell cycleGO:005144540.011
neurotransmitter secretionGO:000726940.011
positive regulation of gtpase activityGO:00435471660.011
defense responseGO:00069523150.011
microtubule based processGO:00070172100.011
generation of neuronsGO:00486991520.011
cellular response to nitrogen compoundGO:19016991440.011
carboxylic acid transportGO:0046942630.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
dna repairGO:00062811980.011
organic acid catabolic processGO:0016054710.011
nucleocytoplasmic transportGO:00069131760.011
regulation of cell morphogenesisGO:00226041530.011
cellular calcium ion homeostasisGO:00068741170.011
epithelium developmentGO:00604292270.011
oxidation reduction processGO:00551143960.011
stem cell divisionGO:001714520.011
organic hydroxy compound metabolic processGO:19016151470.011
rna splicingGO:00083801310.011
protein localization to nucleusGO:00345041360.011
posttranscriptional regulation of gene expressionGO:00106082130.011
atp catabolic processGO:00062001570.011
cilium morphogenesisGO:0060271750.011
negative regulation of protein maturationGO:19033181420.011
regulation of secretion by cellGO:19035301770.011
negative regulation of protein modification processGO:00314002000.011
cellular response to organonitrogen compoundGO:00714171240.011
regulation of dna metabolic processGO:00510521530.011
peptidyl tyrosine modificationGO:00182121700.011
response to fungusGO:000962040.011
negative regulation of phosphorylationGO:00423261740.011
response to organonitrogen compoundGO:00102431560.011
establishment of protein localization to organelleGO:00725941720.011
regulation of nervous system developmentGO:0051960880.011
neural tube formationGO:000184130.010
cellular ion homeostasisGO:00068731680.010
cell projection morphogenesisGO:00488581290.010
regulation of cytoplasmic transportGO:19036491490.010
chromatin modificationGO:00165682980.010
rhythmic behaviorGO:000762220.010
alcohol metabolic processGO:00060661140.010
negative regulation of growthGO:0045926970.010
signal releaseGO:0023061700.010
salivary gland morphogenesisGO:000743540.010
epithelium migrationGO:00901321190.010
cell morphogenesis involved in differentiationGO:00009041440.010
proteasomal protein catabolic processGO:00104981760.010
mrna metabolic processGO:00160711750.010
negative regulation of transferase activityGO:00513481240.010
response to other organismGO:00517072610.010
regulation of ion transportGO:00432691890.010
regulation of dephosphorylationGO:0035303960.010
response to activityGO:001482300.010
organic acid transportGO:0015849650.010
inorganic cation transmembrane transportGO:00986621940.010
regulation of cell developmentGO:00602841610.010
regulation of protein modification by small protein conjugation or removalGO:19033201070.010
cell cell signalingGO:00072671550.010

SPPL2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.047
inherited metabolic disorderDOID:6552420.029
sensory system diseaseDOID:00501552030.018
nervous system diseaseDOID:8634310.018
musculoskeletal system diseaseDOID:172230.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.014
organ system cancerDOID:00506861640.013
central nervous system diseaseDOID:3311860.012
eye and adnexa diseaseDOID:14921500.012
immune system diseaseDOID:29141550.012
eye diseaseDOID:56141490.011
neurodegenerative diseaseDOID:12891020.010
bone diseaseDOID:0080001880.010
connective tissue diseaseDOID:651090.010
brain diseaseDOID:936730.010