Homo sapiens

139 known processes

ARHGEF18

Rho/Rac guanine nucleotide exchange factor (GEF) 18

(Aliases: P114-RhoGEF,MGC15913,KIAA0521)

ARHGEF18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.086
cellular amine metabolic processGO:0044106410.067
cellular amino acid metabolic processGO:00065201160.067
cellular ketone metabolic processGO:0042180800.061
amine metabolic processGO:0009308440.060
regulation of cellular ketone metabolic processGO:0010565500.058
ras protein signal transductionGO:0007265730.058
regulation of cellular amine metabolic processGO:0033238110.054
purine ribonucleoside metabolic processGO:00461284370.054
purine nucleoside triphosphate metabolic processGO:00091444120.052
regulation of cellular amino acid metabolic processGO:000652160.052
multicellular organismal agingGO:001025930.050
ribonucleoside triphosphate catabolic processGO:00092033910.049
nucleoside phosphate catabolic processGO:19012924120.046
glycosyl compound catabolic processGO:19016584130.045
small gtpase mediated signal transductionGO:0007264780.045
purine nucleoside catabolic processGO:00061523980.044
nucleoside catabolic processGO:00091644080.042
ribonucleoside triphosphate metabolic processGO:00091994120.042
female gamete generationGO:000729220.041
purine containing compound catabolic processGO:00725234110.040
ribonucleoside catabolic processGO:00424544060.039
nucleotide catabolic processGO:00091664080.039
cellular macromolecule catabolic processGO:00442653800.038
locomotory behaviorGO:000762610.038
nucleoside triphosphate metabolic processGO:00091414220.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
vesicle mediated transportGO:00161923710.038
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
ribonucleotide catabolic processGO:00092614050.036
nucleoside triphosphate catabolic processGO:00091433940.036
actin filament based processGO:00300292240.035
organophosphate catabolic processGO:00464344300.035
positive regulation of catabolic processGO:00098963100.035
negative regulation of protein metabolic processGO:00512483910.035
purine ribonucleoside catabolic processGO:00461303980.034
segmentationGO:003528240.034
regulation of cell cycleGO:00517263930.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
mitotic cell cycleGO:00002783260.034
positive regulation of hydrolase activityGO:00513453310.033
purine nucleoside triphosphate catabolic processGO:00091463920.033
endomembrane system organizationGO:00102561960.032
cytoplasmic transportGO:00164823790.032
positive regulation of cellular amine metabolic processGO:003324070.032
cellular response to dna damage stimulusGO:00069743790.032
determination of adult lifespanGO:000834020.032
positive regulation of purine nucleotide metabolic processGO:19005442270.032
membrane organizationGO:00610242920.032
positive regulation of cellular catabolic processGO:00313312840.031
negative regulation of phosphate metabolic processGO:00459362670.031
chromatin modificationGO:00165682980.031
negative regulation of cellular protein metabolic processGO:00322693530.031
oogenesisGO:004847720.031
rho protein signal transductionGO:0007266260.031
blastoderm segmentationGO:000735020.030
histone modificationGO:00165702510.030
regulation of nucleoside metabolic processGO:00091182090.029
negative regulation of catalytic activityGO:00430863350.029
negative regulation of phosphorus metabolic processGO:00105632670.029
gtp metabolic processGO:00460392390.029
guanosine containing compound metabolic processGO:19010682440.028
single organism cellular localizationGO:19025803320.028
covalent chromatin modificationGO:00165692540.028
immune responseGO:00069553070.028
nervous system developmentGO:00073992930.027
purine nucleotide catabolic processGO:00061954050.027
positive regulation of cellular component organizationGO:00511303760.027
regulation of locomotionGO:00400123290.026
positive regulation of cell proliferationGO:00082843010.026
mitotic cell cycle processGO:19030472860.026
protein catabolic processGO:00301633250.026
purine ribonucleotide catabolic processGO:00091544040.026
biological adhesionGO:00226103310.026
chromatin organizationGO:00063253510.025
regulation of protein localizationGO:00328802960.025
negative regulation of cellular amine metabolic processGO:003323930.025
spermatid developmentGO:000728640.025
regulation of purine nucleotide catabolic processGO:00331212050.025
regulation of cell differentiationGO:00455953930.024
cell adhesionGO:00071553250.024
lipid metabolic processGO:00066293810.024
regulation of small gtpase mediated signal transductionGO:00510561560.024
Human
positive regulation of nucleotide metabolic processGO:00459812300.024
positive regulation of nucleoside metabolic processGO:00459791860.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.024
cell morphogenesisGO:00009022960.024
positive regulation of purine nucleotide catabolic processGO:00331231850.024
protein localization to organelleGO:00333652800.024
gtp catabolic processGO:00061842370.023
regulation of purine nucleotide metabolic processGO:19005422640.023
microtubule based processGO:00070172100.023
Human
positive regulation of transportGO:00510503360.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
protein modification by small protein conjugationGO:00324463420.023
regulation of cell cycle processGO:00105642660.023
single organism membrane organizationGO:00448022680.023
oocyte differentiationGO:000999420.023
cellular protein catabolic processGO:00442572610.023
regulation of nucleotide metabolic processGO:00061402690.023
regulation of cellular component movementGO:00512703340.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
cellular lipid metabolic processGO:00442553030.023
positive regulation of nucleotide catabolic processGO:00308131850.023
regulation of cell motilityGO:20001452990.023
actin cytoskeleton organizationGO:00300362070.022
defense responseGO:00069523150.022
chemical homeostasisGO:00488783060.022
positive regulation of immune system processGO:00026842830.022
oocyte developmentGO:004859910.022
neuromuscular junction developmentGO:000752830.022
regulation of cellular response to stressGO:00801352440.021
negative regulation of intracellular signal transductionGO:19025321830.021
cellular component morphogenesisGO:00329893140.021
dephosphorylationGO:00163112090.021
regulation of neural precursor cell proliferationGO:200017740.021
mapk cascadeGO:00001652880.021
cell projection organizationGO:00300302520.021
regulation of gtp catabolic processGO:00331241800.021
positive regulation of developmental processGO:00510943140.021
regenerationGO:003109940.021
regulation of establishment of protein localizationGO:00702012420.021
secretion by cellGO:00329402260.021
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of protein modification processGO:00314002000.021
anterior posterior axis specificationGO:000994820.020
positive regulation of gtp catabolic processGO:00331261660.020
regulation of proteolysisGO:00301622930.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
protein ubiquitinationGO:00165673140.020
cell developmentGO:00484683280.020
regulation of transferase activityGO:00513383550.020
memoryGO:000761330.020
anterior posterior axis specification embryoGO:000859520.020
intracellular protein transportGO:00068862700.020
growthGO:00400072020.020
modification dependent macromolecule catabolic processGO:00436322120.020
regulation of cell migrationGO:00303342890.020
negative regulation of programmed cell deathGO:00430693210.020
positive regulation of neural precursor cell proliferationGO:200017920.020
maintenance of locationGO:00512351120.019
innate immune responseGO:00450871780.019
response to external biotic stimulusGO:00432072610.019
positive regulation of phosphorylationGO:00423273940.019
Human
system processGO:00030083490.019
cellular protein complex assemblyGO:00436231880.019
regulation of protein kinase activityGO:00458592890.019
regulation of kinase activityGO:00435493140.019
proteasomal protein catabolic processGO:00104981760.019
negative regulation of cellular component organizationGO:00511292350.019
Human
response to abiotic stimulusGO:00096283360.019
regulation of anatomical structure morphogenesisGO:00226032860.019
protein maturationGO:00516042330.019
compound eye developmentGO:004874910.018
regulation of response to external stimulusGO:00321012220.018
cell cycle phase transitionGO:00447701730.018
negative regulation of cell deathGO:00605483450.018
regulation of cellular component biogenesisGO:00440872810.018
negative regulation of phosphorylationGO:00423261740.018
guanosine containing compound catabolic processGO:19010692390.018
apoptotic signaling pathwayGO:00971902680.018
signal transduction by phosphorylationGO:00230142970.017
secretionGO:00469032540.017
regulation of gtpase activityGO:00430871800.017
transmembrane transportGO:00550853990.017
regulation of multi organism processGO:00439001570.017
regulation of nucleotide catabolic processGO:00308112050.017
tripartite regional subdivisionGO:000735120.017
regulation of protein transportGO:00512232130.017
negative regulation of developmental processGO:00510932470.017
cytokine productionGO:00018162470.017
Human
positive regulation of ras gtpase activityGO:00323201170.017
Human
modification dependent protein catabolic processGO:00199412090.017
regulation of cytokine productionGO:00018172320.017
Human
adult locomotory behaviorGO:000834410.017
epithelium developmentGO:00604292270.017
cell divisionGO:00513011680.017
hindbrain developmentGO:003090230.017
negative regulation of hydrolase activityGO:00513461820.017
response to oxygen containing compoundGO:19017003690.017
Human
positive regulation of gtpase activityGO:00435471660.017
response to biotic stimulusGO:00096072760.016
negative regulation of apoptotic processGO:00430663160.016
negative regulation of cell cycleGO:00457861930.016
positive regulation of protein phosphorylationGO:00019343130.016
Human
cation transportGO:00068123310.016
organelle assemblyGO:00709251760.016
neurological system processGO:00508771630.016
regulation of mitotic cell cycleGO:00073461890.016
regulation of ras gtpase activityGO:00323181280.016
Human
regulation of immune responseGO:00507762010.016
single organism cell adhesionGO:00986021790.016
endocytosisGO:00068971590.016
response to other organismGO:00517072610.016
carbohydrate metabolic processGO:00059752070.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of multicellular organismal processGO:00512413170.016
spermatid differentiationGO:004851540.016
rhythmic behaviorGO:000762220.016
epithelial cell differentiationGO:00308551410.016
brain morphogenesisGO:004885410.016
ubiquitin dependent protein catabolic processGO:00065112060.016
oxidation reduction processGO:00551143960.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
cardiovascular system developmentGO:00723582620.015
positive regulation of organelle organizationGO:00106381950.015
negative regulation of protein phosphorylationGO:00019331400.015
regulation of secretionGO:00510461940.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
Human
associative learningGO:000830610.015
microtubule cytoskeleton organizationGO:00002261760.015
Human
cell activationGO:00017752130.015
actin filament organizationGO:00070151280.015
Human
regulation of cytoskeleton organizationGO:00514931770.015
Human
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
cellular response to endogenous stimulusGO:00714953360.015
Human
atp metabolic processGO:00460341760.015
protein localization to membraneGO:00726571600.015
regulation of cell morphogenesisGO:00226041530.015
regulation of mapk cascadeGO:00434082620.015
motor neuron axon guidanceGO:000804520.014
cell growthGO:00160491600.014
positive regulation of synaptic transmissionGO:005080640.014
visual behaviorGO:000763220.014
endosomal transportGO:00161971290.014
cellular response to oxygen containing compoundGO:19017012760.014
Human
morphogenesis of embryonic epitheliumGO:001633140.014
carbohydrate derivative biosynthetic processGO:19011372070.014
protein processingGO:00164852260.014
positive regulation of cellular component biogenesisGO:00440891580.014
organelle fissionGO:00482851490.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
neurotransmitter secretionGO:000726940.014
posttranscriptional regulation of gene expressionGO:00106082130.014
positive regulation of cell deathGO:00109422630.014
nitrogen compound transportGO:00717051910.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
establishment of protein localization to membraneGO:00901501210.014
regulation of protein catabolic processGO:00421761550.014
interspecies interaction between organismsGO:00444191560.014
inner ear morphogenesisGO:004247240.014
dna repairGO:00062811980.014
regulation of ras protein signal transductionGO:00465781550.014
Human
negative regulation of cell proliferationGO:00082852280.014
mitotic cell cycle phase transitionGO:00447721620.014
regulation of growthGO:00400081650.014
head developmentGO:00603221080.014
regulation of intracellular transportGO:00323861950.013
protein oligomerizationGO:00512591730.013
neurogenesisGO:00220081690.013
rna processingGO:00063962550.013
organonitrogen compound biosynthetic processGO:19015662000.013
organophosphate biosynthetic processGO:00904071630.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
protein acylationGO:00435431380.013
positive regulation of programmed cell deathGO:00430682490.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
anion transportGO:00068201610.013
nucleoside monophosphate metabolic processGO:00091231910.013
embryonic epithelial tube formationGO:000183840.013
hemopoiesisGO:00300971800.013
central nervous system developmentGO:00074171230.013
regulation of secretion by cellGO:19035301770.013
metal ion transportGO:00300012720.013
peptidyl tyrosine phosphorylationGO:00181081700.013
Human
mitotic nuclear divisionGO:00070671190.013
positive regulation of locomotionGO:00400171860.013
single organism carbohydrate metabolic processGO:00447231930.013
positive regulation of immune responseGO:00507781590.013
regulation of vesicle mediated transportGO:00606271300.013
immune system developmentGO:00025201950.013
reactive oxygen species biosynthetic processGO:190340940.013
immune effector processGO:00022521590.013
negative regulation of transferase activityGO:00513481240.013
ion transmembrane transportGO:00342203380.013
plasma membrane organizationGO:00070091150.013
metencephalon developmentGO:002203720.013
regulation of chromosome organizationGO:00330441030.013
multi organism cellular processGO:00447641560.013
protein targetingGO:00066051870.013
photoreceptor cell differentiationGO:004653020.012
negative regulation of transportGO:00510511760.012
response to virusGO:00096151260.012
regulation of cell growthGO:00015581350.012
sex determinationGO:000753030.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
negative regulation of organelle organizationGO:00106391260.012
Human
cation transmembrane transportGO:00986552380.012
cellular component disassemblyGO:0022411920.012
Human
peripheral nervous system developmentGO:000742220.012
response to fungusGO:000962040.012
ion homeostasisGO:00508012300.012
organic hydroxy compound metabolic processGO:19016151470.012
regulation of protein processingGO:00706131500.012
cell fate determinationGO:000170930.012
regulation of cell cycle phase transitionGO:19019871260.012
viral processGO:00160321460.012
regulation of rho protein signal transductionGO:0035023790.012
Human
defense response to virusGO:0051607710.012
circadian behaviorGO:004851220.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
ameboidal type cell migrationGO:00016671350.012
positive regulation of cell differentiationGO:00455972110.012
positive regulation of kinase activityGO:00336742040.012
generation of neuronsGO:00486991520.012
matingGO:000761810.012
reactive oxygen species metabolic processGO:0072593750.012
golgi vesicle transportGO:0048193800.012
regulation of synaptic plasticityGO:004816730.011
cation homeostasisGO:00550801890.011
leukocyte activationGO:00453211640.011
positive regulation of cellular component movementGO:00512721810.011
regulation of defense responseGO:00313471540.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
regulation of protein serine threonine kinase activityGO:00719001790.011
endoplasmic reticulum organizationGO:0007029200.011
regulation of protein maturationGO:19033171500.011
small molecule biosynthetic processGO:00442831570.011
peptidyl lysine modificationGO:00182051440.011
lipid biosynthetic processGO:00086101770.011
inorganic ion transmembrane transportGO:00986602310.011
cell projection assemblyGO:00300311260.011
regulation of dna metabolic processGO:00510521530.011
brain developmentGO:0007420970.011
response to axon injuryGO:004867810.011
sensory perception of painGO:001923340.011
neuroblast proliferationGO:000740540.011
morphogenesis of a polarized epitheliumGO:000173830.011
neural tube formationGO:000184130.011
reactive nitrogen species metabolic processGO:200105730.011
syncytium formation by plasma membrane fusionGO:000076820.011
mrna metabolic processGO:00160711750.011
actin mediated cell contractionGO:0070252120.011
positive regulation of protein kinase activityGO:00458601900.011
nerve developmentGO:002167540.011
protein autophosphorylationGO:00467771230.011
cerebellum developmentGO:002154920.011
regulation of protein complex assemblyGO:00432541470.011
cell projection morphogenesisGO:00488581290.011
cellular response to cytokine stimulusGO:00713451810.011
organ morphogenesisGO:00098871470.011
positive regulation of transferase activityGO:00513472270.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
thymus developmentGO:004853830.011
wnt signaling pathwayGO:00160551560.011
cellular homeostasisGO:00197251960.011
atp catabolic processGO:00062001570.011
blood vessel developmentGO:00015681720.011
positive regulation of cell motilityGO:20001471770.011
cdc42 protein signal transductionGO:003248840.011
defense response to other organismGO:00985421290.011
monocarboxylic acid metabolic processGO:00327871850.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
regulation of apoptotic signaling pathwayGO:20012331750.011
tube developmentGO:00352951250.011
nuclear divisionGO:00002801280.011
actin filament based movementGO:0030048170.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
negative regulation of cell cycle processGO:00109481210.010
regulation of cell projection organizationGO:00313441070.010
g protein coupled receptor signaling pathwayGO:00071862070.010
peptidyl lysine acetylationGO:00183941010.010
tissue migrationGO:00901301190.010
positive regulation of mapk cascadeGO:00434101900.010
cell part morphogenesisGO:00329901370.010
i kappab kinase nf kappab signalingGO:00072491660.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
vasculature developmentGO:00019441810.010
cell morphogenesis involved in differentiationGO:00009041440.010
cellular cation homeostasisGO:00300031630.010
response to woundingGO:00096111680.010
phospholipid metabolic processGO:0006644990.010
response to nitrogen compoundGO:19016981840.010
Human
regulation of cell divisionGO:00513021160.010
protein localization to nucleusGO:00345041360.010
glycerophospholipid metabolic processGO:0006650840.010
cell substrate adhesionGO:00315891320.010
protein homooligomerizationGO:00512601000.010
regulation of cytoplasmic transportGO:19036491490.010
salivary gland morphogenesisGO:000743540.010
lymphocyte activationGO:00466491330.010
inorganic cation transmembrane transportGO:00986621940.010
defense response to fungusGO:005083240.010
activation of immune responseGO:00022531140.010
circulatory system developmentGO:00723592620.010
glycerolipid metabolic processGO:00464861070.010
rna interferenceGO:001624640.010
negative regulation of cell differentiationGO:00455961710.010
regulation of response to dna damage stimulusGO:2001020940.010
tube closureGO:006060630.010
long term memoryGO:000761620.010

ARHGEF18 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
sensory system diseaseDOID:00501552030.019
disease of metabolismDOID:00146672950.019
musculoskeletal system diseaseDOID:172230.018
inherited metabolic disorderDOID:6552420.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
neurodegenerative diseaseDOID:12891020.014
eye diseaseDOID:56141490.013
eye and adnexa diseaseDOID:14921500.013
immune system diseaseDOID:29141550.012
connective tissue diseaseDOID:651090.011
muscular diseaseDOID:00800001140.010
retinal diseaseDOID:56791180.010