Homo sapiens

6 known processes

PIK3C2A

phosphoinositide-3-kinase, class 2, alpha polypeptide

(Aliases: MGC142218,CPK,PI3-K-C2(ALPHA),PI3-K-C2A,DKFZp686L193)

PIK3C2A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161923710.262
membrane organizationGO:00610242920.199
Worm
nucleoside phosphate catabolic processGO:19012924120.149
glycosyl compound catabolic processGO:19016584130.127
purine ribonucleoside triphosphate catabolic processGO:00092073910.125
purine ribonucleotide catabolic processGO:00091544040.123
ras protein signal transductionGO:0007265730.122
purine nucleotide catabolic processGO:00061954050.122
cytoplasmic transportGO:00164823790.121
nervous system developmentGO:00073992930.117
endomembrane system organizationGO:00102561960.115
single organism membrane organizationGO:00448022680.109
positive regulation of nucleoside metabolic processGO:00459791860.102
cellular ketone metabolic processGO:0042180800.096
purine nucleoside triphosphate catabolic processGO:00091463920.095
nucleoside triphosphate catabolic processGO:00091433940.093
single organism cellular localizationGO:19025803320.089
system processGO:00030083490.086
female gamete generationGO:000729220.080
positive regulation of cellular component organizationGO:00511303760.080
Worm
purine containing compound catabolic processGO:00725234110.080
mitotic cell cycleGO:00002783260.078
organophosphate catabolic processGO:00464344300.078
purine ribonucleoside metabolic processGO:00461284370.078
cell cell signalingGO:00072671550.078
positive regulation of purine nucleotide catabolic processGO:00331231850.077
nucleotide catabolic processGO:00091664080.077
purine ribonucleoside triphosphate metabolic processGO:00092054110.076
hindbrain developmentGO:003090230.072
nucleoside catabolic processGO:00091644080.072
immune responseGO:00069553070.071
positive regulation of cellular amine metabolic processGO:003324070.069
positive regulation of hydrolase activityGO:00513453310.069
ribonucleoside triphosphate catabolic processGO:00092033910.069
small gtpase mediated signal transductionGO:0007264780.068
neuron differentiationGO:00301821380.065
regulation of cellular component biogenesisGO:00440872810.063
determination of adult lifespanGO:000834020.063
cellular response to growth factor stimulusGO:00713631970.063
regulation of purine nucleotide catabolic processGO:00331212050.063
ribonucleoside catabolic processGO:00424544060.063
positive regulation of gtpase activityGO:00435471660.062
cell projection organizationGO:00300302520.062
purine ribonucleoside catabolic processGO:00461303980.060
regulation of protein localizationGO:00328802960.059
regulation of gtp catabolic processGO:00331241800.059
ribonucleoside triphosphate metabolic processGO:00091994120.058
response to growth factorGO:00708482050.056
purine nucleoside catabolic processGO:00061523980.056
purine nucleoside triphosphate metabolic processGO:00091444120.055
positive regulation of ras gtpase activityGO:00323201170.055
regulation of cellular amine metabolic processGO:0033238110.053
regulation of cellular amino acid metabolic processGO:000652160.053
regulation of anatomical structure morphogenesisGO:00226032860.052
organ morphogenesisGO:00098871470.052
maintenance of locationGO:00512351120.051
Worm
nucleoside triphosphate metabolic processGO:00091414220.051
regulation of purine nucleotide metabolic processGO:19005422640.050
positive regulation of catabolic processGO:00098963100.050
cellular macromolecular complex assemblyGO:00346223240.049
cellular protein complex assemblyGO:00436231880.048
neuromuscular junction developmentGO:000752830.047
cell developmentGO:00484683280.046
enzyme linked receptor protein signaling pathwayGO:00071673030.045
glycerolipid metabolic processGO:00464861070.045
Human Mouse Worm Fly
positive regulation of gtp catabolic processGO:00331261660.044
morphogenesis of embryonic epitheliumGO:001633140.044
cellular amine metabolic processGO:0044106410.044
cellular lipid metabolic processGO:00442553030.043
Human Mouse Worm Fly
actin filament based processGO:00300292240.043
Fly
embryonic epithelial tube formationGO:000183840.043
regulation of nucleotide metabolic processGO:00061402690.042
regulation of nucleoside metabolic processGO:00091182090.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
generation of neuronsGO:00486991520.042
microtubule based processGO:00070172100.042
positive regulation of cellular catabolic processGO:00313312840.041
gtp catabolic processGO:00061842370.041
negative regulation of phosphorus metabolic processGO:00105632670.041
cellular component morphogenesisGO:00329893140.040
rho protein signal transductionGO:0007266260.040
oogenesisGO:004847720.040
cellular amino acid metabolic processGO:00065201160.039
positive regulation of purine nucleotide metabolic processGO:19005442270.039
transmission of nerve impulseGO:0019226110.039
cellular response to endogenous stimulusGO:00714953360.039
regulation of kinase activityGO:00435493140.039
morphogenesis of a polarized epitheliumGO:000173830.038
regulation of protein complex assemblyGO:00432541470.038
regulation of gtpase activityGO:00430871800.037
ribonucleotide catabolic processGO:00092614050.036
protein targetingGO:00066051870.036
regulation of nucleotide catabolic processGO:00308112050.036
innate immune responseGO:00450871780.036
regulation of cell differentiationGO:00455953930.036
inner ear morphogenesisGO:004247240.036
neuron developmentGO:00486661130.035
oocyte developmentGO:004859910.035
guanosine containing compound catabolic processGO:19010692390.035
neurological system processGO:00508771630.034
regulation of membrane potentialGO:0042391950.034
negative regulation of catalytic activityGO:00430863350.034
neurogenesisGO:00220081690.033
amine metabolic processGO:0009308440.033
positive regulation of developmental processGO:00510943140.033
mitotic cell cycle processGO:19030472860.032
microtubule cytoskeleton organizationGO:00002261760.032
regulation of immune responseGO:00507762010.032
cytokine productionGO:00018162470.032
behaviorGO:00076101120.031
retrograde transport endosome to golgiGO:0042147450.031
regulation of transferase activityGO:00513383550.031
cell morphogenesisGO:00009022960.031
multicellular organismal agingGO:001025930.031
endosomal transportGO:00161971290.030
secretionGO:00469032540.029
regulation of cellular ketone metabolic processGO:0010565500.029
regulation of establishment of protein localizationGO:00702012420.029
post embryonic developmentGO:000979120.029
Worm
multicellular organismal signalingGO:0035637340.029
biological adhesionGO:00226103310.029
regulation of cytoskeleton organizationGO:00514931770.029
positive regulation of nucleotide metabolic processGO:00459812300.028
growthGO:00400072020.028
plasma membrane organizationGO:00070091150.028
protein deubiquitinationGO:0016579790.028
mapk cascadeGO:00001652880.028
protein localization to plasma membraneGO:0072659930.028
chemical homeostasisGO:00488783060.028
protein localization to organelleGO:00333652800.027
neuron projection developmentGO:00311751060.027
endocytosisGO:00068971590.027
positive regulation of immune system processGO:00026842830.027
intracellular protein transportGO:00068862700.026
dephosphorylationGO:00163112090.026
negative regulation of cellular component organizationGO:00511292350.026
neural tube formationGO:000184130.026
action potentialGO:0001508340.026
immune effector processGO:00022521590.026
protein localization to membraneGO:00726571600.026
wnt signaling pathwayGO:00160551560.026
epithelium developmentGO:00604292270.026
carbohydrate metabolic processGO:00059752070.025
positive regulation of kinase activityGO:00336742040.025
positive regulation of nucleotide catabolic processGO:00308131850.025
guanosine containing compound metabolic processGO:19010682440.025
metencephalon developmentGO:002203720.025
interspecies interaction between organismsGO:00444191560.025
cytokinesisGO:0000910960.024
ribonucleoside monophosphate catabolic processGO:00091581580.024
regulation of ras protein signal transductionGO:00465781550.024
cell adhesionGO:00071553250.024
positive regulation of protein phosphorylationGO:00019343130.024
secretion by cellGO:00329402260.024
negative regulation of cellular protein metabolic processGO:00322693530.024
protein modification by small protein conjugationGO:00324463420.024
negative regulation of protein modification processGO:00314002000.023
positive regulation of transportGO:00510503360.023
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.023
regulation of cell cycleGO:00517263930.023
positive regulation of programmed cell deathGO:00430682490.023
regulation of growthGO:00400081650.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
positive regulation of apoptotic processGO:00430652460.022
regulation of ras gtpase activityGO:00323181280.022
maintenance of cell polarityGO:003001120.022
regulation of defense responseGO:00313471540.021
cell part morphogenesisGO:00329901370.021
primary neural tube formationGO:001402030.021
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of cell morphogenesisGO:00226041530.021
protein localization to nucleusGO:00345041360.021
positive regulation of organelle organizationGO:00106381950.021
positive regulation of transferase activityGO:00513472270.021
positive regulation of protein kinase activityGO:00458601900.021
establishment of tissue polarityGO:000716430.021
leukocyte activationGO:00453211640.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.021
regulation of mapk cascadeGO:00434082620.020
positive regulation of cytoskeleton organizationGO:0051495830.020
spindle elongationGO:005123140.020
atp catabolic processGO:00062001570.020
protein ubiquitinationGO:00165673140.020
oocyte differentiationGO:000999420.020
nucleoside monophosphate catabolic processGO:00091251590.020
embryonic morphogenesisGO:0048598850.020
nucleocytoplasmic transportGO:00069131760.020
rab protein signal transductionGO:003248240.020
ossificationGO:00015031210.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
negative regulation of phosphorylationGO:00423261740.020
regulation of locomotionGO:00400123290.020
establishment of protein localization to organelleGO:00725941720.020
signal transduction by phosphorylationGO:00230142970.020
behavioral response to ethanolGO:004814920.020
cell projection morphogenesisGO:00488581290.020
regulation of multi organism processGO:00439001570.019
defense responseGO:00069523150.019
neuronal action potentialGO:001922890.019
transmembrane transportGO:00550853990.019
Mouse
actin cytoskeleton organizationGO:00300362070.019
Fly
locomotory behaviorGO:000762610.019
positive regulation of cell deathGO:00109422630.019
negative regulation of immune system processGO:00026831360.019
regulation of cell motilityGO:20001452990.019
metal ion transportGO:00300012720.019
Mouse
establishment of protein localization to plasma membraneGO:0090002680.019
regulation of actin cytoskeleton organizationGO:00329561160.018
regulation of response to external stimulusGO:00321012220.018
negative regulation of cell proliferationGO:00082852280.018
regulation of map kinase activityGO:00434051080.018
actin filament organizationGO:00070151280.018
glycerophospholipid metabolic processGO:0006650840.018
Human Mouse Worm Fly
atp metabolic processGO:00460341760.018
hair cell differentiationGO:003531520.018
multi organism cellular processGO:00447641560.018
negative regulation of protein metabolic processGO:00512483910.018
response to transforming growth factor betaGO:0071559940.018
peptidyl serine phosphorylationGO:00181051010.018
regulation of cellular component movementGO:00512703340.017
establishment of organelle localizationGO:0051656590.017
phospholipid metabolic processGO:0006644990.017
Human Mouse Worm Fly
negative regulation of intracellular signal transductionGO:19025321830.017
golgi vesicle transportGO:0048193800.017
gtp metabolic processGO:00460392390.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
positive regulation of cytokine productionGO:00018191670.017
memoryGO:000761330.017
establishment of protein localization to membraneGO:00901501210.017
regulation of vesicle mediated transportGO:00606271300.016
Worm
lipid localizationGO:00108761060.016
Worm
negative regulation of transportGO:00510511760.016
Mouse
peptidyl tyrosine phosphorylationGO:00181081700.016
negative regulation of cellular amine metabolic processGO:003323930.016
response to cytokineGO:00340972320.016
organelle fissionGO:00482851490.016
neural tube closureGO:000184330.016
negative regulation of kinase activityGO:00336731060.016
regulation of protein kinase activityGO:00458592890.016
single organism carbohydrate metabolic processGO:00447231930.016
rna processingGO:00063962550.016
cellular response to abiotic stimulusGO:00712141170.016
regulation of innate immune responseGO:0045088970.016
immune system developmentGO:00025201950.016
cardiovascular system developmentGO:00723582620.016
protein autophosphorylationGO:00467771230.016
transforming growth factor beta receptor signaling pathwayGO:0007179760.015
cellular component assembly involved in morphogenesisGO:0010927730.015
activation of protein kinase activityGO:0032147900.015
establishment or maintenance of bipolar cell polarityGO:006124520.015
blastoderm segmentationGO:000735020.015
negative regulation of cell deathGO:00605483450.015
Human
regulation of anatomical structure sizeGO:00900661010.015
peptidyl serine modificationGO:00182091060.015
viral processGO:00160321460.015
mitotic nuclear divisionGO:00070671190.015
positive regulation of cell proliferationGO:00082843010.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
aorta morphogenesisGO:003590910.015
organelle assemblyGO:00709251760.015
modification dependent macromolecule catabolic processGO:00436322120.015
regulation of intracellular transportGO:00323861950.015
response to abiotic stimulusGO:00096283360.015
protein maturationGO:00516042330.015
cellular chemical homeostasisGO:00550821800.014
negative regulation of transferase activityGO:00513481240.014
regulation of cell adhesionGO:00301551660.014
tissue morphogenesisGO:0048729960.014
spermatid differentiationGO:004851540.014
chromosome segregationGO:00070591140.014
maintenance of location in cellGO:0051651620.014
positive regulation of cell motilityGO:20001471770.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
morphogenesis of an epitheliumGO:0002009600.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
positive regulation of canonical wnt signaling pathwayGO:0090263330.014
nuclear transportGO:00511691790.014
response to biotic stimulusGO:00096072760.014
blood vessel developmentGO:00015681720.014
microtubule organizing center organizationGO:0031023620.014
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.014
response to woundingGO:00096111680.014
negative regulation of protein phosphorylationGO:00019331400.013
regulation of actin filament based processGO:00329701410.013
cell morphogenesis involved in differentiationGO:00009041440.013
cell divisionGO:00513011680.013
mitotic spindle elongationGO:000002240.013
spermatid developmentGO:000728640.013
central nervous system developmentGO:00074171230.013
positive regulation of cell migrationGO:00303351720.013
cellular carbohydrate metabolic processGO:0044262840.013
negative regulation of hydrolase activityGO:00513461820.013
osteoblast differentiationGO:0001649920.013
regulation of secretionGO:00510461940.013
rna interferenceGO:001624640.013
negative regulation of multicellular organismal processGO:00512413170.013
brain developmentGO:0007420970.013
organonitrogen compound biosynthetic processGO:19015662000.013
lipid transportGO:0006869900.013
regulation of antimicrobial humoral responseGO:000275910.013
cation transportGO:00068123310.013
Mouse
nitrogen compound transportGO:00717051910.013
stress activated mapk cascadeGO:0051403930.013
regulation of proteolysisGO:00301622930.013
positive regulation of immune responseGO:00507781590.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
matingGO:000761810.012
canonical wnt signaling pathwayGO:00600701160.012
myosin filament assemblyGO:003103420.012
protein catabolic processGO:00301633250.012
positive regulation of locomotionGO:00400171860.012
response to radiationGO:00093141510.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
jnk cascadeGO:0007254800.012
regulation of dna metabolic processGO:00510521530.012
protein oligomerizationGO:00512591730.012
chromatin modificationGO:00165682980.012
erbb signaling pathwayGO:0038127440.012
negative regulation of protein transportGO:0051224750.012
regulation of protein serine threonine kinase activityGO:00719001790.012
head developmentGO:00603221080.012
regulation of response to woundingGO:19030341010.012
single organismal cell cell adhesionGO:00163371480.012
regulation of cell cycle processGO:00105642660.012
autophagyGO:0006914880.012
regulation of cell projection organizationGO:00313441070.012
long term memoryGO:000761620.012
regulation of rab gtpase activityGO:0032313390.012
regulation of cytokine productionGO:00018172320.012
dna replicationGO:00062601160.012
cell growthGO:00160491600.012
regulation of immune effector processGO:0002697910.012
cell matrix adhesionGO:0007160850.012
regulation of homeostatic processGO:00328441210.012
cell cell junction organizationGO:0045216690.012
cell projection assemblyGO:00300311260.012
regulation of protein transportGO:00512232130.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
g protein coupled receptor signaling pathwayGO:00071862070.011
actin filament polymerizationGO:0030041450.011
regulation of rho protein signal transductionGO:0035023790.011
neuron projection morphogenesisGO:0048812500.011
epithelial cell differentiationGO:00308551410.011
positive regulation of wnt signaling pathwayGO:0030177540.011
reproductive processGO:00224141060.011
vesicle organizationGO:0016050620.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
small molecule biosynthetic processGO:00442831570.011
peptidyl tyrosine modificationGO:00182121700.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
regulation of cytoplasmic transportGO:19036491490.011
tube closureGO:006060630.011
cation homeostasisGO:00550801890.011
regulation of cellular component sizeGO:0032535820.011
compound eye developmentGO:004874910.011
posttranscriptional regulation of gene expressionGO:00106082130.011
regulation of chromosome organizationGO:00330441030.011
associative learningGO:000830610.011
receptor mediated endocytosisGO:0006898840.011
response to external biotic stimulusGO:00432072610.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
regulation of apoptotic signaling pathwayGO:20012331750.011
lymphocyte activationGO:00466491330.011
negative regulation of apoptotic processGO:00430663160.011
Human
cerebellum developmentGO:002154920.011
apoptotic signaling pathwayGO:00971902680.011
cellular component disassemblyGO:0022411920.010
jak stat cascadeGO:0007259460.010
regulation of wnt signaling pathwayGO:00301111230.010
striated muscle myosin thick filament assemblyGO:007168820.010
regulation of hormone levelsGO:00108171250.010
dna repairGO:00062811980.010
embryo developmentGO:00097901230.010
vasculature developmentGO:00019441810.010
positive regulation of cellular component movementGO:00512721810.010
carbohydrate derivative biosynthetic processGO:19011372070.010
proteasomal protein catabolic processGO:00104981760.010
regulation of neural precursor cell proliferationGO:200017740.010
regulation of cell developmentGO:00602841610.010
negative regulation of organelle organizationGO:00106391260.010
segmentationGO:003528240.010
anion transportGO:00068201610.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010
meiotic chromosome segregationGO:004513240.010
response to light stimulusGO:0009416870.010

PIK3C2A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.030
Human
cancerDOID:1621670.030
Human
organ system cancerDOID:00506861640.029
Human
sensory system diseaseDOID:00501552030.016
nervous system diseaseDOID:8634310.016
retinal diseaseDOID:56791180.011
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011