Homo sapiens

71 known processes

TNKS2

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2

(Aliases: PARP5B,PARP5C,pART6,TANK2,PARP-5c,PARP-5b,TNKL)

TNKS2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
angiotensin activated signaling pathwayGO:003816640.907
cellular response to oxygen levelsGO:0071453550.344
protein glycosylationGO:0006486620.342
protein ubiquitinationGO:00165673140.331
response to abiotic stimulusGO:00096283360.305
cellular response to decreased oxygen levelsGO:0036294510.302
cellular response to hypoxiaGO:0071456510.276
protein modification by small protein conjugationGO:00324463420.261
regulation of neuronal synaptic plasticityGO:004816810.247
glycoprotein biosynthetic processGO:0009101910.211
response to hypoxiaGO:0001666960.197
canonical wnt signaling pathwayGO:00600701160.188
peptidyl serine phosphorylationGO:00181051010.175
Human
cell developmentGO:00484683280.171
response to oxygen levelsGO:00704821000.167
regulation of canonical wnt signaling pathwayGO:0060828880.149
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.144
regulation of synaptic plasticityGO:004816730.142
oxidation reduction processGO:00551143960.137
neuromuscular junction developmentGO:000752830.132
regulation of striated muscle tissue developmentGO:0016202260.128
response to decreased oxygen levelsGO:0036293960.127
small gtpase mediated signal transductionGO:0007264780.121
post embryonic developmentGO:000979120.117
peptide metabolic processGO:0006518510.103
carbohydrate metabolic processGO:00059752070.098
positive regulation of developmental processGO:00510943140.091
mitotic cell cycle processGO:19030472860.091
response to external biotic stimulusGO:00432072610.089
muscle structure developmentGO:0061061980.089
macromolecule glycosylationGO:0043413630.088
positive regulation of myoblast differentiationGO:004566360.087
peptidyl serine modificationGO:00182091060.086
Human
regulation of ras protein signal transductionGO:00465781550.081
nucleotide catabolic processGO:00091664080.080
regulation of cellular component biogenesisGO:00440872810.080
Fly
regulation of nucleoside metabolic processGO:00091182090.079
notch signaling pathwayGO:0007219310.079
system processGO:00030083490.077
ras protein signal transductionGO:0007265730.076
amine metabolic processGO:0009308440.074
positive regulation of catabolic processGO:00098963100.073
glycosylationGO:0070085710.072
purine ribonucleoside triphosphate catabolic processGO:00092073910.069
rho protein signal transductionGO:0007266260.067
guanosine containing compound catabolic processGO:19010692390.066
carbohydrate derivative biosynthetic processGO:19011372070.066
purine ribonucleoside triphosphate metabolic processGO:00092054110.064
purine ribonucleotide catabolic processGO:00091544040.062
determination of adult lifespanGO:000834020.061
female gamete generationGO:000729220.061
cellular response to dna damage stimulusGO:00069743790.061
purine ribonucleoside metabolic processGO:00461284370.060
immune responseGO:00069553070.059
cellular amino acid metabolic processGO:00065201160.059
response to biotic stimulusGO:00096072760.059
positive regulation of canonical wnt signaling pathwayGO:0090263330.057
positive regulation of transportGO:00510503360.057
regulation of purine nucleotide metabolic processGO:19005422640.057
purine nucleotide catabolic processGO:00061954050.056
ribonucleoside triphosphate catabolic processGO:00092033910.056
single organism carbohydrate metabolic processGO:00447231930.055
cellular macromolecular complex assemblyGO:00346223240.055
Fly
ribonucleoside triphosphate metabolic processGO:00091994120.054
locomotory behaviorGO:000762610.052
g protein coupled receptor signaling pathwayGO:00071862070.051
cytoplasmic transportGO:00164823790.051
purine containing compound catabolic processGO:00725234110.050
response to other organismGO:00517072610.050
regulation of cell differentiationGO:00455953930.050
synaptic transmissionGO:0007268610.049
regulation of telomere maintenance via telomeraseGO:003221060.048
Human
protein localization to organelleGO:00333652800.047
defense responseGO:00069523150.047
ribonucleoside catabolic processGO:00424544060.046
cellular macromolecule catabolic processGO:00442653800.046
nucleoside triphosphate catabolic processGO:00091433940.045
wnt signaling pathwayGO:00160551560.045
protein catabolic processGO:00301633250.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
response to hormoneGO:00097251750.044
cellular amine metabolic processGO:0044106410.044
cellular component morphogenesisGO:00329893140.044
regulation of telomere maintenanceGO:0032204130.044
Human
protein deubiquitinationGO:0016579790.043
purine ribonucleoside catabolic processGO:00461303980.043
glycerolipid metabolic processGO:00464861070.043
regulation of nucleotide catabolic processGO:00308112050.043
muscle fiber developmentGO:0048747160.043
endocrine processGO:0050886250.042
negative regulation of bindingGO:0051100570.042
Human
purine nucleoside triphosphate metabolic processGO:00091444120.042
regulation of small gtpase mediated signal transductionGO:00510561560.041
neuropeptide catabolic processGO:001081320.041
cellular amide metabolic processGO:0043603690.041
negative regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006142840.039
regulation of cellular amino acid metabolic processGO:000652160.039
positive regulation of gtp catabolic processGO:00331261660.039
chromatin organizationGO:00063253510.039
mitotic cell cycleGO:00002783260.039
proteolysis involved in cellular protein catabolic processGO:00516032440.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
nucleoside catabolic processGO:00091644080.039
negative regulation of notch signaling pathwayGO:0045746100.038
skeletal muscle fiber developmentGO:0048741120.038
regulation of striated muscle cell differentiationGO:0051153250.038
positive regulation of purine nucleotide catabolic processGO:00331231850.037
response to woundingGO:00096111680.036
positive regulation of muscle cell differentiationGO:0051149150.036
regulation of protein complex assemblyGO:00432541470.036
Fly
gtp catabolic processGO:00061842370.035
myoblast differentiationGO:0045445210.035
neural tube formationGO:000184130.035
positive regulation of organelle organizationGO:00106381950.035
Human
cellular response to abiotic stimulusGO:00712141170.035
maintenance of locationGO:00512351120.035
covalent chromatin modificationGO:00165692540.035
regulation of cellular amine metabolic processGO:0033238110.034
guanosine containing compound metabolic processGO:19010682440.034
oogenesisGO:004847720.034
regulation of myoblast differentiationGO:0045661120.034
apoptotic signaling pathwayGO:00971902680.033
positive regulation of nucleotide metabolic processGO:00459812300.033
hindbrain developmentGO:003090230.032
response to bacteriumGO:00096171440.032
organelle assemblyGO:00709251760.031
nucleoside triphosphate metabolic processGO:00091414220.031
lipid metabolic processGO:00066293810.030
multicellular organismal agingGO:001025930.030
membrane organizationGO:00610242920.030
embryonic epithelial tube formationGO:000183840.030
organ formationGO:004864530.030
regulation of gtp catabolic processGO:00331241800.030
protein polyubiquitinationGO:00002091100.030
regulation of systemic arterial blood pressureGO:0003073190.029
glycosyl compound catabolic processGO:19016584130.029
neurological system processGO:00508771630.029
positive regulation of gtpase activityGO:00435471660.029
ribonucleotide catabolic processGO:00092614050.029
regulation of blood pressureGO:0008217300.028
regulation of muscle organ developmentGO:0048634270.028
muscle cell differentiationGO:0042692630.028
nucleoside phosphate catabolic processGO:19012924120.028
positive regulation of cellular catabolic processGO:00313312840.027
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044120.027
regulation of establishment of protein localizationGO:00702012420.027
limbic system developmentGO:002176130.026
memoryGO:000761330.026
cell projection organizationGO:00300302520.026
cellular protein complex assemblyGO:00436231880.026
Fly
regulation of cell cycleGO:00517263930.026
positive regulation of cellular component organizationGO:00511303760.026
Human
mitotic nuclear divisionGO:00070671190.026
regulation of bindingGO:00510981110.026
Human
innate immune responseGO:00450871780.026
regulation of chromosome organizationGO:00330441030.026
Human
regulation of proteolysisGO:00301622930.026
cellular response to radiationGO:0071478650.025
positive regulation of phosphorylationGO:00423273940.025
nervous system developmentGO:00073992930.025
positive regulation of dna metabolic processGO:0051054730.025
Human
regulation of anatomical structure morphogenesisGO:00226032860.025
positive regulation of hydrolase activityGO:00513453310.025
cell cycle checkpointGO:00000751170.024
gtp metabolic processGO:00460392390.024
telomere maintenance via telomere lengtheningGO:001083390.024
Human
metencephalon developmentGO:002203720.024
response to radiationGO:00093141510.024
glycoprotein metabolic processGO:00091001100.024
regulation of response to external stimulusGO:00321012220.024
actin cytoskeleton organizationGO:00300362070.024
membrane protein ectodomain proteolysisGO:0006509330.024
negative regulation of cellular protein metabolic processGO:00322693530.023
regulation of dna metabolic processGO:00510521530.023
Human
regulation of gtpase activityGO:00430871800.023
negative regulation of cellular component organizationGO:00511292350.023
epithelium developmentGO:00604292270.023
endomembrane system organizationGO:00102561960.023
behaviorGO:00076101120.023
dna integrity checkpointGO:0031570710.023
cellular chemical homeostasisGO:00550821800.023
positive regulation of wnt signaling pathwayGO:0030177540.023
protein dephosphorylationGO:0006470810.023
regulation of nucleotide metabolic processGO:00061402690.023
positive regulation of immune system processGO:00026842830.023
membrane protein proteolysisGO:0033619380.022
positive regulation of cell differentiationGO:00455972110.022
positive regulation of protein transportGO:00512221350.022
dna damage checkpointGO:0000077680.022
protein processingGO:00164852260.022
cell fate determinationGO:000170930.022
cardiovascular system developmentGO:00723582620.022
microtubule based processGO:00070172100.022
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.021
purine nucleoside catabolic processGO:00061523980.021
response to uvGO:0009411730.021
regulation of microtubule polymerizationGO:0031113120.021
cellular carbohydrate metabolic processGO:0044262840.021
protein polymerizationGO:0051258710.021
regulation of growthGO:00400081650.021
Mouse
chromosome segregationGO:00070591140.020
head developmentGO:00603221080.020
small molecule biosynthetic processGO:00442831570.020
regulation of muscle cell differentiationGO:0051147310.020
neural tube closureGO:000184330.020
dna replicationGO:00062601160.020
Human
inner ear morphogenesisGO:004247240.020
peptidyl threonine phosphorylationGO:0018107410.020
Human
oocyte differentiationGO:000999420.019
regulation of rho protein signal transductionGO:0035023790.019
blood circulationGO:00080151130.019
regulation of cellular ketone metabolic processGO:0010565500.019
cell cell signalingGO:00072671550.019
regulation of cytoskeleton organizationGO:00514931770.019
morphogenesis of embryonic epitheliumGO:001633140.019
regulation of protein ubiquitinationGO:0031396950.019
chemical homeostasisGO:00488783060.019
regulation of muscle tissue developmentGO:1901861260.019
cell morphogenesisGO:00009022960.019
positive regulation of cellular amine metabolic processGO:003324070.019
muscle organ developmentGO:0007517560.019
somitogenesisGO:000175620.019
organic hydroxy compound metabolic processGO:19016151470.019
striated muscle cell differentiationGO:0051146430.019
cellular protein catabolic processGO:00442572610.019
positive regulation of ras gtpase activityGO:00323201170.019
cell activationGO:00017752130.019
organelle fissionGO:00482851490.018
positive regulation of cell cycleGO:00457871400.018
central nervous system developmentGO:00074171230.018
response to ionizing radiationGO:0010212650.018
rhythmic behaviorGO:000762220.018
organophosphate catabolic processGO:00464344300.018
glycerophospholipid metabolic processGO:0006650840.018
dephosphorylationGO:00163112090.018
nuclear divisionGO:00002801280.018
adult locomotory behaviorGO:000834410.018
leukocyte differentiationGO:0002521980.018
actin filament based processGO:00300292240.017
regulation of cell cycle processGO:00105642660.017
positive regulation of intracellular transportGO:00323881040.017
protein adp ribosylationGO:000647190.017
muscle tissue developmentGO:0060537620.017
modification dependent macromolecule catabolic processGO:00436322120.017
negative regulation of cell proliferationGO:00082852280.017
oocyte developmentGO:004859910.017
protein maturationGO:00516042330.017
heart developmentGO:0007507950.017
segmentationGO:003528240.017
tube closureGO:006060630.017
brain developmentGO:0007420970.017
chromatin modificationGO:00165682980.017
regulation of skeletal muscle fiber developmentGO:0048742120.017
wound healingGO:00420601150.017
melanin metabolic processGO:000658210.017
regulation of intracellular transportGO:00323861950.017
skeletal muscle organ developmentGO:0060538260.016
cell fate commitment involved in pattern specificationGO:006058110.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
positive regulation of nucleoside metabolic processGO:00459791860.016
protein homooligomerizationGO:00512601000.016
regulation of immune responseGO:00507762010.016
regulation of microtubule cytoskeleton organizationGO:0070507610.016
signal transduction by phosphorylationGO:00230142970.016
generation of neuronsGO:00486991520.016
regulation of response to dna damage stimulusGO:2001020940.016
regulation of glycoprotein metabolic processGO:1903018190.016
regulation of purine nucleotide catabolic processGO:00331212050.016
modification dependent protein catabolic processGO:00199412090.015
negative regulation of proteolysisGO:00458611320.015
mitochondrion organizationGO:00070051560.015
positive regulation of cellular component movementGO:00512721810.015
cellular response to endogenous stimulusGO:00714953360.015
lipid localizationGO:00108761060.015
positive regulation of protein phosphorylationGO:00019343130.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
negative regulation of catalytic activityGO:00430863350.015
cell adhesionGO:00071553250.015
negative regulation of organelle organizationGO:00106391260.015
nuclear transportGO:00511691790.015
demethylationGO:0070988370.015
microtubule cytoskeleton organizationGO:00002261760.015
ubiquitin dependent protein catabolic processGO:00065112060.015
peptide catabolic processGO:0043171100.015
circulatory system processGO:00030131130.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
cell type specific apoptotic processGO:00972851250.014
biological adhesionGO:00226103310.014
regulation of cell cycle phase transitionGO:19019871260.014
morphogenesis of a polarized epitheliumGO:000173830.014
regulation of rho gtpase activityGO:0032319660.014
protein hydroxylationGO:001812690.014
protein k63 linked deubiquitinationGO:0070536210.014
nucleoside monophosphate catabolic processGO:00091251590.014
hemopoiesisGO:00300971800.014
calcium ion homeostasisGO:00550741220.014
golgi vesicle transportGO:0048193800.014
regulation of cytoplasmic transportGO:19036491490.014
positive regulation of telomere maintenanceGO:003220640.014
Human
primary neural tube formationGO:001402030.014
spermatid developmentGO:000728640.014
regulation of response to woundingGO:19030341010.014
organophosphate biosynthetic processGO:00904071630.014
single organism membrane organizationGO:00448022680.014
regulation of cellular component movementGO:00512703340.014
positive regulation of protein localization to nucleusGO:1900182480.014
regulation of protein localizationGO:00328802960.014
activation of immune responseGO:00022531140.013
regulation of meiotic cell cycleGO:005144540.013
regulation of neural precursor cell proliferationGO:200017740.013
behavioral response to ethanolGO:004814920.013
peptidyl tyrosine modificationGO:00182121700.013
rna catabolic processGO:0006401710.013
regulation of protein maturationGO:19033171500.013
muscle cell developmentGO:0055001290.013
response to nitrogen compoundGO:19016981840.013
signal transduction by p53 class mediatorGO:0072331720.013
compound eye developmentGO:004874910.013
cellular homeostasisGO:00197251960.013
regulation of cell divisionGO:00513021160.013
regulation of cell motilityGO:20001452990.013
neuroblast proliferationGO:000740540.013
protein oligomerizationGO:00512591730.013
immune effector processGO:00022521590.013
anterior posterior axis specificationGO:000994820.013
neurogenesisGO:00220081690.013
cellular divalent inorganic cation homeostasisGO:00725031280.012
cellular metal ion homeostasisGO:00068751460.012
regulation of mapk cascadeGO:00434082620.012
reproductionGO:0000003630.012
spermatid differentiationGO:004851540.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
cellular ketone metabolic processGO:0042180800.012
regulation of cellular response to stressGO:00801352440.012
skeletal muscle tissue developmentGO:0007519240.012
negative regulation of protein metabolic processGO:00512483910.012
dna templated transcription initiationGO:0006352350.012
regulation of cellular carbohydrate metabolic processGO:0010675470.012
regulation of skeletal muscle tissue developmentGO:0048641150.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
regulation of myotube differentiationGO:0010830180.012
organ morphogenesisGO:00098871470.012
cell part morphogenesisGO:00329901370.012
histone modificationGO:00165702510.012
regulation of cell morphogenesisGO:00226041530.012
negative regulation of protein processingGO:00109551420.012
regulation of dna templated transcription in response to stressGO:0043620180.012
regulation of transferase activityGO:00513383550.012
regulation of mitotic cell cycleGO:00073461890.012
associative learningGO:000830610.012
muscle cell cellular homeostasisGO:004671630.012
nucleocytoplasmic transportGO:00069131760.012
transmembrane transportGO:00550853990.012
macromolecule methylationGO:0043414970.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
positive regulation of cytoplasmic transportGO:1903651820.012
cell growthGO:00160491600.011
atp metabolic processGO:00460341760.011
negative regulation of protein catabolic processGO:0042177590.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.011
myotube differentiationGO:0014902220.011
cellular response to uvGO:0034644320.011
neurotransmitter secretionGO:000726940.011
histone methylationGO:0016571600.011
circadian behaviorGO:004851220.011
circulatory system developmentGO:00723592620.011
organelle localizationGO:0051640840.011
regulation of synaptic vesicle transportGO:190280330.011
protein targetingGO:00066051870.011
nucleoside monophosphate metabolic processGO:00091231910.011
positive regulation of protein complex assemblyGO:0031334860.011
anatomical structure homeostasisGO:00602491000.011
Human
response to light stimulusGO:0009416870.011
sister chromatid segregationGO:0000819540.011
tissue regenerationGO:004224630.011
regulation of nuclear divisionGO:0051783650.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
mapk cascadeGO:00001652880.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
protein modification by small protein removalGO:0070646920.011
positive regulation of transferase activityGO:00513472270.011
regulation of ion transportGO:00432691890.011
negative regulation of phosphorus metabolic processGO:00105632670.011
endocytosisGO:00068971590.011
protein localization to membraneGO:00726571600.011
cellular lipid metabolic processGO:00442553030.011
myoblast fusionGO:000752010.011
embryo developmentGO:00097901230.011
positive regulation of nucleotide catabolic processGO:00308131850.011
synaptic vesicle recyclingGO:003646530.011
intracellular steroid hormone receptor signaling pathwayGO:0030518610.011
regulation of microtubule polymerization or depolymerizationGO:0031110270.011
inflammatory responseGO:0006954790.011
maintenance of location in cellGO:0051651620.011
hair cell differentiationGO:003531520.010
divalent inorganic cation homeostasisGO:00725071360.010
regulation of erk1 and erk2 cascadeGO:0070372990.010
regulation of protein processingGO:00706131500.010
i kappab kinase nf kappab signalingGO:00072491660.010
regulation of gene expression epigeneticGO:0040029730.010
regulation of stress activated mapk cascadeGO:0032872840.010
intracellular protein transportGO:00068862700.010
ion transmembrane transportGO:00342203380.010
negative regulation of intracellular signal transductionGO:19025321830.010
regulation of meiosisGO:004002030.010
posttranscriptional regulation of gene expressionGO:00106082130.010
meiotic chromosome segregationGO:004513240.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
ion homeostasisGO:00508012300.010
cell divisionGO:00513011680.010
regulation of ras gtpase activityGO:00323181280.010
mitotic cell cycle phase transitionGO:00447721620.010
cerebral cortex radially oriented cell migrationGO:002179910.010
regulation of neurotransmitter secretionGO:004692830.010
cation homeostasisGO:00550801890.010
regulation of epithelial cell proliferationGO:00506781130.010

TNKS2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.050
cancerDOID:1621670.042
organ system cancerDOID:00506861640.024
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
eye diseaseDOID:56141490.014
eye and adnexa diseaseDOID:14921500.014
gastrointestinal system cancerDOID:3119520.012
central nervous system diseaseDOID:3311860.012
musculoskeletal system diseaseDOID:172230.010