Homo sapiens

0 known processes

GDF15

growth differentiation factor 15

(Aliases: GDF-15,NAG-1,MIC1,PTGFB,MIC-1,PDF,PLAB)

GDF15 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.167
amine metabolic processGO:0009308440.158
cellular amine metabolic processGO:0044106410.146
cellular ketone metabolic processGO:0042180800.138
regulation of cellular ketone metabolic processGO:0010565500.132
regulation of cellular amino acid metabolic processGO:000652160.119
positive regulation of cellular amine metabolic processGO:003324070.117
regulation of cellular amine metabolic processGO:0033238110.106
positive regulation of cellular amino acid metabolic processGO:004576430.101
response to oxygen containing compoundGO:19017003690.091
lipid metabolic processGO:00066293810.077
oxidation reduction processGO:00551143960.077
apoptotic signaling pathwayGO:00971902680.074
response to abiotic stimulusGO:00096283360.068
positive regulation of phosphorylationGO:00423273940.068
negative regulation of cell deathGO:00605483450.066
chemical homeostasisGO:00488783060.065
positive regulation of apoptotic processGO:00430652460.064
transmembrane transportGO:00550853990.062
positive regulation of transportGO:00510503360.061
positive regulation of protein phosphorylationGO:00019343130.061
ion transmembrane transportGO:00342203380.060
regulation of locomotionGO:00400123290.060
cation transportGO:00068123310.060
negative regulation of protein metabolic processGO:00512483910.059
epithelium developmentGO:00604292270.058
post embryonic developmentGO:000979120.058
positive regulation of cellular component organizationGO:00511303760.057
Mouse
cellular lipid metabolic processGO:00442553030.056
regulation of cell migrationGO:00303342890.056
negative regulation of catalytic activityGO:00430863350.055
system processGO:00030083490.051
response to biotic stimulusGO:00096072760.051
regulation of kinase activityGO:00435493140.049
regulation of proteolysisGO:00301622930.049
negative regulation of cellular protein metabolic processGO:00322693530.048
response to lipidGO:00339932060.047
monocarboxylic acid metabolic processGO:00327871850.047
regulation of protein localizationGO:00328802960.046
response to other organismGO:00517072610.045
immune responseGO:00069553070.044
positive regulation of cell deathGO:00109422630.044
regulation of cell motilityGO:20001452990.043
lipid biosynthetic processGO:00086101770.043
negative regulation of programmed cell deathGO:00430693210.043
regulation of secretionGO:00510461940.043
response to hormoneGO:00097251750.043
secretionGO:00469032540.042
positive regulation of programmed cell deathGO:00430682490.042
defense responseGO:00069523150.041
carbohydrate metabolic processGO:00059752070.041
anion transportGO:00068201610.040
regulation of transferase activityGO:00513383550.040
response to organic cyclic compoundGO:00140702040.040
regulation of protein kinase activityGO:00458592890.039
cation homeostasisGO:00550801890.039
cellular response to oxygen containing compoundGO:19017012760.039
metal ion transportGO:00300012720.039
protein maturationGO:00516042330.039
cellular macromolecule catabolic processGO:00442653800.039
response to external biotic stimulusGO:00432072610.038
negative regulation of phosphate metabolic processGO:00459362670.038
positive regulation of organelle organizationGO:00106381950.038
carboxylic acid biosynthetic processGO:0046394970.038
determination of adult lifespanGO:000834020.038
negative regulation of phosphorus metabolic processGO:00105632670.038
regulation of cell differentiationGO:00455953930.037
Mouse
regulation of cellular component biogenesisGO:00440872810.037
cellular response to endogenous stimulusGO:00714953360.037
regulation of cellular component movementGO:00512703340.037
regulation of cell cycleGO:00517263930.037
cytoplasmic transportGO:00164823790.036
negative regulation of apoptotic processGO:00430663160.036
multicellular organismal agingGO:001025930.035
regulation of apoptotic signaling pathwayGO:20012331750.034
cell adhesionGO:00071553250.034
morphogenesis of embryonic epitheliumGO:001633140.034
fatty acid metabolic processGO:00066311150.034
response to cytokineGO:00340972320.034
protein processingGO:00164852260.033
positive regulation of cellular catabolic processGO:00313312840.033
nitrogen compound transportGO:00717051910.033
carbohydrate derivative biosynthetic processGO:19011372070.033
extrinsic apoptotic signaling pathwayGO:00971911190.033
reactive oxygen species metabolic processGO:0072593750.032
hemopoiesisGO:00300971800.032
regulation of hormone levelsGO:00108171250.032
positive regulation of developmental processGO:00510943140.032
Mouse
protein localization to organelleGO:00333652800.032
positive regulation of hydrolase activityGO:00513453310.032
mitotic cell cycleGO:00002783260.032
positive regulation of catabolic processGO:00098963100.032
positive regulation of cell proliferationGO:00082843010.031
small gtpase mediated signal transductionGO:0007264780.031
single organism carbohydrate metabolic processGO:00447231930.031
negative regulation of developmental processGO:00510932470.031
calcium ion transportGO:00068161470.030
organic anion transportGO:00157111030.030
mitotic cell cycle processGO:19030472860.030
mapk cascadeGO:00001652880.030
regulation of response to external stimulusGO:00321012220.030
female gamete generationGO:000729220.030
regulation of establishment of protein localizationGO:00702012420.030
response to inorganic substanceGO:00100351270.030
ion homeostasisGO:00508012300.030
response to oxidative stressGO:00069791210.029
protein oligomerizationGO:00512591730.029
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.029
biological adhesionGO:00226103310.029
regulation of cell cycle processGO:00105642660.029
regulation of endopeptidase activityGO:00525481700.029
small molecule biosynthetic processGO:00442831570.028
regulation of cellular response to stressGO:00801352440.028
signal transduction by phosphorylationGO:00230142970.028
response to woundingGO:00096111680.028
protein catabolic processGO:00301633250.028
cellular chemical homeostasisGO:00550821800.028
positive regulation of transferase activityGO:00513472270.028
regulation of peptidase activityGO:00525471800.028
locomotory behaviorGO:000762610.028
purine nucleoside triphosphate metabolic processGO:00091444120.027
negative regulation of cell proliferationGO:00082852280.027
cellular cation homeostasisGO:00300031630.027
regulation of mitotic cell cycleGO:00073461890.027
regulation of anatomical structure morphogenesisGO:00226032860.027
Mouse
actin filament based processGO:00300292240.027
organic acid biosynthetic processGO:0016053970.027
negative regulation of multicellular organismal processGO:00512413170.027
negative regulation of protein modification processGO:00314002000.027
rho protein signal transductionGO:0007266260.027
cellular homeostasisGO:00197251960.027
ras protein signal transductionGO:0007265730.027
negative regulation of cellular component organizationGO:00511292350.026
regulation of sequence specific dna binding transcription factor activityGO:00510902110.026
nucleoside catabolic processGO:00091644080.026
intrinsic apoptotic signaling pathwayGO:00971931270.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
ribonucleotide catabolic processGO:00092614050.026
cellular component morphogenesisGO:00329893140.026
cytokine productionGO:00018162470.026
positive regulation of immune system processGO:00026842830.026
organ morphogenesisGO:00098871470.025
cardiovascular system developmentGO:00723582620.025
divalent metal ion transportGO:00708381520.025
regulation of ion transportGO:00432691890.025
single organism membrane organizationGO:00448022680.025
cellular response to dna damage stimulusGO:00069743790.025
response to nitrogen compoundGO:19016981840.025
single organism cellular localizationGO:19025803320.024
regulation of multi organism processGO:00439001570.024
positive regulation of cell motilityGO:20001471770.024
glycosyl compound catabolic processGO:19016584130.024
posttranscriptional regulation of gene expressionGO:00106082130.024
response to decreased oxygen levelsGO:0036293960.024
negative regulation of intracellular signal transductionGO:19025321830.024
cellular protein catabolic processGO:00442572610.024
response to hypoxiaGO:0001666960.024
organonitrogen compound biosynthetic processGO:19015662000.024
purine ribonucleoside metabolic processGO:00461284370.024
growthGO:00400072020.024
symbiosis encompassing mutualism through parasitismGO:00444031560.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
response to organonitrogen compoundGO:00102431560.024
negative regulation of hydrolase activityGO:00513461820.024
regulation of protein complex assemblyGO:00432541470.024
regulation of protein maturationGO:19033171500.024
hematopoietic or lymphoid organ developmentGO:00485341860.024
regulation of mapk cascadeGO:00434082620.023
cellular response to external stimulusGO:00714961110.023
oogenesisGO:004847720.023
mitochondrion organizationGO:00070051560.023
regulation of cytokine productionGO:00018172320.023
ameboidal type cell migrationGO:00016671350.023
regulation of protein transportGO:00512232130.023
purine nucleotide catabolic processGO:00061954050.023
negative regulation of cell cycleGO:00457861930.022
innate immune responseGO:00450871780.022
reactive oxygen species biosynthetic processGO:190340940.022
hindbrain developmentGO:003090230.022
regenerationGO:003109940.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
regulation of reactive oxygen species metabolic processGO:2000377410.022
metal ion homeostasisGO:00550651690.022
dephosphorylationGO:00163112090.022
regulation of cytoskeleton organizationGO:00514931770.022
organophosphate catabolic processGO:00464344300.022
epithelial cell differentiationGO:00308551410.022
regulation of defense responseGO:00313471540.022
cation transmembrane transportGO:00986552380.022
intracellular protein transportGO:00068862700.022
maintenance of locationGO:00512351120.022
negative regulation of cell migrationGO:00303361020.021
segmentationGO:003528240.021
secretion by cellGO:00329402260.021
cellular component disassemblyGO:0022411920.021
cellular response to cytokine stimulusGO:00713451810.021
peptidyl tyrosine phosphorylationGO:00181081700.021
nucleoside triphosphate catabolic processGO:00091433940.021
divalent inorganic cation transportGO:00725111580.021
cell developmentGO:00484683280.021
purine nucleoside catabolic processGO:00061523980.021
hormone metabolic processGO:0042445610.021
regulation of protein serine threonine kinase activityGO:00719001790.021
myeloid cell differentiationGO:00300991170.021
nucleoside phosphate catabolic processGO:19012924120.020
regulation of body fluid levelsGO:0050878990.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
tube developmentGO:00352951250.020
cell morphogenesisGO:00009022960.020
regulation of protein processingGO:00706131500.020
positive regulation of protein kinase activityGO:00458601900.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
neuromuscular junction developmentGO:000752830.020
negative regulation of protein maturationGO:19033181420.020
cellular macromolecular complex assemblyGO:00346223240.020
negative regulation of cellular component movementGO:00512711060.020
negative regulation of transportGO:00510511760.020
negative regulation of proteolysisGO:00458611320.020
positive regulation of proteolysisGO:00458621420.020
cell activationGO:00017752130.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
Mouse
nervous system developmentGO:00073992930.020
cellular response to lipidGO:00713961270.020
cellular divalent inorganic cation homeostasisGO:00725031280.020
inner ear morphogenesisGO:004247240.020
protein modification by small protein conjugationGO:00324463420.020
vasculature developmentGO:00019441810.019
positive regulation of mapk cascadeGO:00434101900.019
positive regulation of cell differentiationGO:00455972110.019
Mouse
immune system developmentGO:00025201950.019
nucleotide catabolic processGO:00091664080.019
purine ribonucleoside catabolic processGO:00461303980.019
cellular metal ion homeostasisGO:00068751460.019
organic hydroxy compound metabolic processGO:19016151470.019
positive regulation of cellular component biogenesisGO:00440891580.019
regulation of metal ion transportGO:00109591200.019
negative regulation of phosphorylationGO:00423261740.019
establishment of protein localization to organelleGO:00725941720.019
protein ubiquitinationGO:00165673140.019
regulation of intracellular transportGO:00323861950.019
ubiquitin dependent protein catabolic processGO:00065112060.019
cellular response to organic cyclic compoundGO:00714071270.019
organ formationGO:004864530.019
cellular response to abiotic stimulusGO:00712141170.019
negative regulation of organelle organizationGO:00106391260.019
negative regulation of protein processingGO:00109551420.019
cellular ion homeostasisGO:00068731680.018
negative regulation of cellular amine metabolic processGO:003323930.018
negative regulation of locomotionGO:00400131180.018
sensory perception of painGO:001923340.018
regulation of immune responseGO:00507762010.018
positive regulation of cell migrationGO:00303351720.018
memoryGO:000761330.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
proteasomal protein catabolic processGO:00104981760.018
embryonic epithelial tube formationGO:000183840.018
regulation of growthGO:00400081650.018
embryonic placenta developmentGO:000189210.018
interspecies interaction between organismsGO:00444191560.018
positive regulation of protein complex assemblyGO:0031334860.018
regulation of protein catabolic processGO:00421761550.018
monocarboxylic acid biosynthetic processGO:0072330670.018
calcium ion homeostasisGO:00550741220.018
single organism cell adhesionGO:00986021790.018
regulation of lipid metabolic processGO:0019216960.018
wound healingGO:00420601150.018
purine containing compound catabolic processGO:00725234110.018
positive regulation of cytokine productionGO:00018191670.018
small molecule catabolic processGO:0044282920.018
positive regulation of kinase activityGO:00336742040.018
salivary gland morphogenesisGO:000743540.018
ribonucleoside catabolic processGO:00424544060.017
nucleoside triphosphate metabolic processGO:00091414220.017
sequestering of metal ionGO:0051238240.017
protein targetingGO:00066051870.017
oocyte differentiationGO:000999420.017
tissue migrationGO:00901301190.017
cell divisionGO:00513011680.017
negative regulation of cell motilityGO:20001461040.017
negative regulation of cell differentiationGO:00455961710.017
positive regulation of cellular component movementGO:00512721810.017
peptidyl serine phosphorylationGO:00181051010.017
cell projection organizationGO:00300302520.017
i kappab kinase nf kappab signalingGO:00072491660.017
negative regulation of kinase activityGO:00336731060.017
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.017
membrane organizationGO:00610242920.017
negative regulation of apoptotic signaling pathwayGO:2001234970.017
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.017
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
purine ribonucleotide catabolic processGO:00091544040.017
divalent inorganic cation homeostasisGO:00725071360.017
cellular response to oxygen levelsGO:0071453550.017
positive regulation of locomotionGO:00400171860.017
modification dependent protein catabolic processGO:00199412090.016
anterior posterior axis specificationGO:000994820.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
phospholipid metabolic processGO:0006644990.016
neurological system processGO:00508771630.016
regulation of ion transmembrane transportGO:00347651320.016
cell cycle phase transitionGO:00447701730.016
cell growthGO:00160491600.016
lipid catabolic processGO:0016042840.016
response to alcoholGO:0097305640.016
regulation of nucleotide metabolic processGO:00061402690.016
response to metal ionGO:0010038840.016
gtp catabolic processGO:00061842370.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
negative regulation of transferase activityGO:00513481240.016
response to virusGO:00096151260.016
guanosine containing compound metabolic processGO:19010682440.016
regulation of bindingGO:00510981110.016
cell chemotaxisGO:00603261120.016
vesicle mediated transportGO:00161923710.015
positive regulation of protein transportGO:00512221350.015
cellular protein complex assemblyGO:00436231880.015
epithelial cell proliferationGO:00506731280.015
mitotic nuclear divisionGO:00070671190.015
response to bacteriumGO:00096171440.015
response to nutrient levelsGO:0031667810.015
regulation of purine nucleotide metabolic processGO:19005422640.015
oocyte developmentGO:004859910.015
regulation of cytoplasmic transportGO:19036491490.015
modification dependent macromolecule catabolic processGO:00436322120.015
regulation of actin filament based processGO:00329701410.015
spermatid differentiationGO:004851540.015
peptidyl tyrosine modificationGO:00182121700.015
regulation of neural precursor cell proliferationGO:200017740.015
response to fungusGO:000962040.015
alcohol metabolic processGO:00060661140.015
sequestering of calcium ionGO:0051208170.015
response to steroid hormoneGO:0048545800.015
regulation of branching involved in ureteric bud morphogenesisGO:009018930.015
protein homooligomerizationGO:00512601000.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
peptidyl serine modificationGO:00182091060.015
organophosphate biosynthetic processGO:00904071630.015
cell type specific apoptotic processGO:00972851250.015
response to drugGO:0042493810.015
regulation of secretion by cellGO:19035301770.015
regulation of gtpase activityGO:00430871800.015
immune effector processGO:00022521590.015
regulation of cell adhesionGO:00301551660.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
regulation of transmembrane transportGO:00347621390.015
actin cytoskeleton organizationGO:00300362070.015
epithelium migrationGO:00901321190.015
regulation of homeostatic processGO:00328441210.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
organelle fissionGO:00482851490.015
chromatin organizationGO:00063253510.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
negative regulation of peptidase activityGO:0010466910.015
reactive nitrogen species metabolic processGO:200105730.015
response to oxygen levelsGO:00704821000.015
organic acid transportGO:0015849650.015
nucleocytoplasmic transportGO:00069131760.015
peripheral nervous system developmentGO:000742220.014
covalent chromatin modificationGO:00165692540.014
neural crest cell developmentGO:001403230.014
positive regulation of nucleotide metabolic processGO:00459812300.014
response to growth factorGO:00708482050.014
nuclear transportGO:00511691790.014
carboxylic acid transportGO:0046942630.014
neurogenesisGO:00220081690.014
positive regulation of cell cycleGO:00457871400.014
protein kinase b signalingGO:0043491690.014
regulation of cell growthGO:00015581350.014
regulation of gtp catabolic processGO:00331241800.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
photoreceptor cell differentiationGO:004653020.014
regulation of epithelial cell proliferationGO:00506781130.014
viral processGO:00160321460.014
protein localization to nucleusGO:00345041360.014
cellular modified amino acid metabolic processGO:0006575640.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
cellular response to hormone stimulusGO:00328701250.014
regulation of cell divisionGO:00513021160.014
cellular response to glucocorticoid stimulusGO:007138540.014
regulation of vesicle mediated transportGO:00606271300.014
regulation of cell developmentGO:00602841610.014
single organismal cell cell adhesionGO:00163371480.014
response to lipopolysaccharideGO:0032496700.014
protein importGO:00170381300.014
gtp metabolic processGO:00460392390.014
positive regulation of immune responseGO:00507781590.014
regulation of epithelial cell migrationGO:0010632930.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
inorganic ion transmembrane transportGO:00986602310.014
tissue morphogenesisGO:0048729960.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
inorganic cation transmembrane transportGO:00986621940.013
epidermis morphogenesisGO:004873030.013
response to endoplasmic reticulum stressGO:0034976490.013
multi organism cellular processGO:00447641560.013
viral life cycleGO:00190581320.013
positive regulation of intracellular transportGO:00323881040.013
protein localization to membraneGO:00726571600.013
hormone transportGO:0009914680.013
response to molecule of bacterial originGO:0002237820.013
leukocyte migrationGO:00509001070.013
regulation of immune effector processGO:0002697910.013
regulation of dna metabolic processGO:00510521530.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
negative regulation of protein phosphorylationGO:00019331400.013
specification of organ identityGO:001009230.013
tissue regenerationGO:004224630.013
regulation of intracellular protein transportGO:00331571230.013
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.013
regulation of viral processGO:00507921030.013
nuclear divisionGO:00002801280.013
histone modificationGO:00165702510.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
glycoprotein metabolic processGO:00091001100.013
negative regulation of mitotic cell cycleGO:00459301020.013
regulation of purine nucleotide catabolic processGO:00331212050.013
regulation of nucleotide catabolic processGO:00308112050.013
chemotaxisGO:00069351570.013
organelle assemblyGO:00709251760.013
blastoderm segmentationGO:000735020.013
regulation of anatomical structure sizeGO:00900661010.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
positive regulation of cell adhesionGO:0045785840.013
chromatin modificationGO:00165682980.013
embryo developmentGO:00097901230.013
central nervous system developmentGO:00074171230.013
cardiac muscle cell contractionGO:008600340.013
endocytosisGO:00068971590.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
adult locomotory behaviorGO:000834410.013
alpha amino acid metabolic processGO:1901605720.013
positive regulation of secretion by cellGO:19035321080.013
negative regulation of cell cycle processGO:00109481210.013
negative regulation of growthGO:0045926970.013
organic acid catabolic processGO:0016054710.013
regulation of map kinase activityGO:00434051080.013
compound eye developmentGO:004874910.012
lipid localizationGO:00108761060.012
ossificationGO:00015031210.012
cellular response to nitrogen compoundGO:19016991440.012
regulation of actin cytoskeleton organizationGO:00329561160.012
matingGO:000761810.012
neuroblast proliferationGO:000740540.012
microtubule based processGO:00070172100.012
negative regulation of endopeptidase activityGO:0010951840.012
generation of neuronsGO:00486991520.012
response to extracellular stimulusGO:0009991850.012
negative regulation of multi organism processGO:0043901920.012
neurotransmitter secretionGO:000726940.012
positive regulation of cell cycle processGO:00900681060.012
regulation of response to woundingGO:19030341010.012
regulation of meiotic cell cycleGO:005144540.012
positive regulation of ion transportGO:0043270870.012
epithelial cell migrationGO:00106311190.012
regulation of cell cycle phase transitionGO:19019871260.012
regulation of ras gtpase activityGO:00323181280.012
steroid metabolic processGO:0008202940.012
mitotic cell cycle phase transitionGO:00447721620.012
endochondral bone morphogenesisGO:006035030.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
blood vessel developmentGO:00015681720.012
stress activated mapk cascadeGO:0051403930.012
positive regulation of nucleoside metabolic processGO:00459791860.012
cellular calcium ion homeostasisGO:00068741170.012
regulation of nucleoside metabolic processGO:00091182090.012
cellular response to hypoxiaGO:0071456510.012
positive regulation of nucleotide catabolic processGO:00308131850.012
lung alveolus developmentGO:004828640.012
negative regulation of response to external stimulusGO:0032102830.012
monosaccharide metabolic processGO:0005996740.012
sensory perceptionGO:00076001030.012
regulation of mesonephros developmentGO:006121730.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
thymus developmentGO:004853830.012
nucleoside monophosphate metabolic processGO:00091231910.012
establishment of protein localization to membraneGO:00901501210.012
leukocyte activationGO:00453211640.012

GDF15 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.035
inherited metabolic disorderDOID:6552420.032
cancerDOID:1621670.023
disease of cellular proliferationDOID:145661740.023
organ system cancerDOID:00506861640.023
musculoskeletal system diseaseDOID:172230.017
nervous system diseaseDOID:8634310.016
sensory system diseaseDOID:00501552030.016
bone diseaseDOID:0080001880.014
connective tissue diseaseDOID:651090.014
central nervous system diseaseDOID:3311860.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
cardiovascular system diseaseDOID:12871060.012