Homo sapiens

49 known processes

SMG6

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)

(Aliases: SMG-6,KIAA0732,C17orf31,EST1A)

SMG6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.090
regulation of cellular amino acid metabolic processGO:000652160.084
amine metabolic processGO:0009308440.071
purine ribonucleoside triphosphate catabolic processGO:00092073910.069
negative regulation of apoptotic processGO:00430663160.069
regulation of cellular amine metabolic processGO:0033238110.068
wnt signaling pathwayGO:00160551560.067
cellular amine metabolic processGO:0044106410.066
regulation of cellular ketone metabolic processGO:0010565500.065
cellular ketone metabolic processGO:0042180800.064
negative regulation of programmed cell deathGO:00430693210.062
purine containing compound catabolic processGO:00725234110.062
purine nucleoside catabolic processGO:00061523980.061
ribonucleotide catabolic processGO:00092614050.061
positive regulation of cellular amine metabolic processGO:003324070.060
cellular amino acid metabolic processGO:00065201160.060
nucleoside catabolic processGO:00091644080.058
dna replicationGO:00062601160.057
regulation of wnt signaling pathwayGO:00301111230.057
purine ribonucleoside catabolic processGO:00461303980.056
nucleoside phosphate catabolic processGO:19012924120.054
positive regulation of cellular amino acid metabolic processGO:004576430.053
small gtpase mediated signal transductionGO:0007264780.052
apoptotic signaling pathwayGO:00971902680.052
glycosyl compound catabolic processGO:19016584130.052
ribonucleoside triphosphate metabolic processGO:00091994120.050
ras protein signal transductionGO:0007265730.049
purine nucleoside triphosphate metabolic processGO:00091444120.049
anatomical structure homeostasisGO:00602491000.049
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
ribonucleoside catabolic processGO:00424544060.047
purine ribonucleoside metabolic processGO:00461284370.046
nucleoside triphosphate metabolic processGO:00091414220.046
nucleotide catabolic processGO:00091664080.046
positive regulation of wnt signaling pathwayGO:0030177540.045
female gamete generationGO:000729220.044
regulation of apoptotic signaling pathwayGO:20012331750.044
purine nucleotide catabolic processGO:00061954050.043
multicellular organismal agingGO:001025930.043
cellular macromolecule catabolic processGO:00442653800.041
organophosphate catabolic processGO:00464344300.041
cellular response to dna damage stimulusGO:00069743790.041
oogenesisGO:004847720.040
nucleoside triphosphate catabolic processGO:00091433940.039
system processGO:00030083490.039
extrinsic apoptotic signaling pathwayGO:00971911190.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
negative regulation of apoptotic signaling pathwayGO:2001234970.037
cell agingGO:0007569520.036
purine ribonucleotide catabolic processGO:00091544040.036
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.036
ribonucleoside triphosphate catabolic processGO:00092033910.035
locomotory behaviorGO:000762610.035
negative regulation of catalytic activityGO:00430863350.035
regulation of cell differentiationGO:00455953930.035
protein modification by small protein conjugationGO:00324463420.034
rho protein signal transductionGO:0007266260.034
chromatin organizationGO:00063253510.034
chromatin modificationGO:00165682980.034
positive regulation of phosphorylationGO:00423273940.033
determination of adult lifespanGO:000834020.033
regulation of purine nucleotide metabolic processGO:19005422640.032
mitotic cell cycle processGO:19030472860.032
cellular macromolecular complex assemblyGO:00346223240.032
cytoplasmic transportGO:00164823790.032
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.031
positive regulation of hydrolase activityGO:00513453310.031
positive regulation of catabolic processGO:00098963100.031
mapk cascadeGO:00001652880.031
regulation of nucleotide metabolic processGO:00061402690.031
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.030
cell morphogenesisGO:00009022960.030
dephosphorylationGO:00163112090.030
Human
gtp metabolic processGO:00460392390.030
guanosine containing compound catabolic processGO:19010692390.030
negative regulation of cell deathGO:00605483450.029
signal transduction by phosphorylationGO:00230142970.029
protein ubiquitinationGO:00165673140.028
lipid metabolic processGO:00066293810.028
telomere maintenanceGO:0000723320.028
positive regulation of cellular component organizationGO:00511303760.028
positive regulation of nucleotide metabolic processGO:00459812300.027
cell adhesionGO:00071553250.027
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.026
regulation of cellular component movementGO:00512703340.026
positive regulation of purine nucleotide metabolic processGO:19005442270.026
guanosine containing compound metabolic processGO:19010682440.026
cellular lipid metabolic processGO:00442553030.026
mitotic cell cycleGO:00002783260.025
gtp catabolic processGO:00061842370.025
regulation of locomotionGO:00400123290.025
regulation of cell motilityGO:20001452990.025
biological adhesionGO:00226103310.025
chemical homeostasisGO:00488783060.025
negative regulation of cellular protein metabolic processGO:00322693530.025
negative regulation of phosphorus metabolic processGO:00105632670.025
neuromuscular junction developmentGO:000752830.025
posttranscriptional regulation of gene expressionGO:00106082130.025
Fly
lung alveolus developmentGO:004828640.025
neuroblast proliferationGO:000740540.025
regulation of cell cycle processGO:00105642660.025
blastoderm segmentationGO:000735020.024
regulation of purine nucleotide catabolic processGO:00331212050.024
actin filament based processGO:00300292240.024
regulation of ras protein signal transductionGO:00465781550.024
negative regulation of protein metabolic processGO:00512483910.024
cation transportGO:00068123310.024
negative regulation of phosphate metabolic processGO:00459362670.024
regulation of mapk cascadeGO:00434082620.024
regulation of cell migrationGO:00303342890.024
signal transduction in absence of ligandGO:0038034220.023
positive regulation of cellular catabolic processGO:00313312840.023
regulation of transferase activityGO:00513383550.023
regulation of nucleoside metabolic processGO:00091182090.023
oocyte differentiationGO:000999420.023
segmentationGO:003528240.023
cell fate determinationGO:000170930.023
single organism cellular localizationGO:19025803320.023
cellular response to endogenous stimulusGO:00714953360.023
cell growthGO:00160491600.023
regulation of protein localizationGO:00328802960.023
oocyte developmentGO:004859910.023
positive regulation of purine nucleotide catabolic processGO:00331231850.022
response to oxygen containing compoundGO:19017003690.022
regulation of kinase activityGO:00435493140.022
positive regulation of nucleoside metabolic processGO:00459791860.022
transmembrane transportGO:00550853990.022
regulation of proteolysisGO:00301622930.022
regulation of gtpase activityGO:00430871800.021
memoryGO:000761330.021
positive regulation of gtp catabolic processGO:00331261660.021
immune responseGO:00069553070.021
secretionGO:00469032540.021
cellular response to oxygen containing compoundGO:19017012760.021
positive regulation of nucleotide catabolic processGO:00308131850.021
microtubule based processGO:00070172100.021
cellular component morphogenesisGO:00329893140.021
neurological system processGO:00508771630.021
nucleocytoplasmic transportGO:00069131760.021
negative regulation of hydrolase activityGO:00513461820.021
regulation of small gtpase mediated signal transductionGO:00510561560.021
positive regulation of gtpase activityGO:00435471660.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
mitotic cell cycle phase transitionGO:00447721620.020
negative regulation of developmental processGO:00510932470.020
nuclear transportGO:00511691790.020
anterior posterior axis specificationGO:000994820.020
defense responseGO:00069523150.020
carbohydrate derivative biosynthetic processGO:19011372070.020
vesicle mediated transportGO:00161923710.020
protein acylationGO:00435431380.019
organ morphogenesisGO:00098871470.019
regulation of cell cycleGO:00517263930.019
organonitrogen compound biosynthetic processGO:19015662000.019
nervous system developmentGO:00073992930.019
regulation of nucleotide catabolic processGO:00308112050.019
cell projection organizationGO:00300302520.019
protein catabolic processGO:00301633250.019
positive regulation of transferase activityGO:00513472270.019
innate immune responseGO:00450871780.019
positive regulation of transportGO:00510503360.019
regulation of cytoplasmic transportGO:19036491490.019
cell developmentGO:00484683280.019
ion homeostasisGO:00508012300.019
hindbrain developmentGO:003090230.019
regulation of growthGO:00400081650.019
regulation of cellular component biogenesisGO:00440872810.018
sex determinationGO:000753030.018
positive regulation of ras gtpase activityGO:00323201170.018
anterior posterior axis specification embryoGO:000859520.018
maintenance of locationGO:00512351120.018
regulation of protein kinase activityGO:00458592890.018
regulation of ras gtpase activityGO:00323181280.018
regulation of establishment of protein localizationGO:00702012420.018
histone modificationGO:00165702510.018
positive regulation of cell proliferationGO:00082843010.018
regulation of intracellular transportGO:00323861950.018
regulation of mitotic cell cycleGO:00073461890.018
response to growth factorGO:00708482050.018
inner ear morphogenesisGO:004247240.018
negative regulation of cellular component organizationGO:00511292350.018
metal ion transportGO:00300012720.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
forebrain generation of neuronsGO:002187230.018
peptidyl lysine modificationGO:00182051440.018
protein maturationGO:00516042330.018
response to cytokineGO:00340972320.018
single organism membrane organizationGO:00448022680.018
lipid biosynthetic processGO:00086101770.018
growthGO:00400072020.017
ion transmembrane transportGO:00342203380.017
response to organic cyclic compoundGO:00140702040.017
protein targetingGO:00066051870.017
dna repairGO:00062811980.017
peripheral nervous system developmentGO:000742220.017
covalent chromatin modificationGO:00165692540.017
oxidation reduction processGO:00551143960.017
cellular protein complex assemblyGO:00436231880.017
negative regulation of multicellular organismal processGO:00512413170.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
carbohydrate metabolic processGO:00059752070.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
positive regulation of protein phosphorylationGO:00019343130.017
negative regulation of protein modification processGO:00314002000.017
translationGO:00064121320.017
negative regulation of cellular amine metabolic processGO:003323930.016
membrane organizationGO:00610242920.016
rna interferenceGO:001624640.016
mrna metabolic processGO:00160711750.016
response to abiotic stimulusGO:00096283360.016
small molecule biosynthetic processGO:00442831570.016
regulation of dephosphorylationGO:0035303960.016
Human
negative regulation of cellular amino acid metabolic processGO:004576320.016
negative regulation of intracellular signal transductionGO:19025321830.016
protein processingGO:00164852260.016
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.016
male genitalia developmentGO:003053910.016
cellular response to cytokine stimulusGO:00713451810.016
inorganic ion transmembrane transportGO:00986602310.016
establishment of protein localization to organelleGO:00725941720.016
organophosphate biosynthetic processGO:00904071630.016
cellular chemical homeostasisGO:00550821800.016
regulation of neural precursor cell proliferationGO:200017740.016
telomere organizationGO:0032200330.016
negative regulation of cell cycleGO:00457861930.016
regulation of cell cycle phase transitionGO:19019871260.015
protein acetylationGO:00064731160.015
cell cycle phase transitionGO:00447701730.015
spermatid differentiationGO:004851540.015
cellular homeostasisGO:00197251960.015
dna conformation changeGO:00711031130.015
associative learningGO:000830610.015
taxisGO:00423301570.015
cation transmembrane transportGO:00986552380.015
cation homeostasisGO:00550801890.015
somatic stem cell maintenanceGO:003501940.015
negative regulation of cell proliferationGO:00082852280.015
response to other organismGO:00517072610.015
compound eye developmentGO:004874910.015
positive regulation of cellular component movementGO:00512721810.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of intracellular protein transportGO:00331571230.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
neurogenesisGO:00220081690.015
cellular protein catabolic processGO:00442572610.015
matingGO:000761810.015
response to external biotic stimulusGO:00432072610.015
cell projection morphogenesisGO:00488581290.015
epithelium migrationGO:00901321190.015
regulation of endopeptidase activityGO:00525481700.015
regulation of cytoskeleton organizationGO:00514931770.015
cellular cation homeostasisGO:00300031630.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
nucleoside monophosphate catabolic processGO:00091251590.015
adult locomotory behaviorGO:000834410.014
organ formationGO:004864530.014
nitrogen compound transportGO:00717051910.014
response to biotic stimulusGO:00096072760.014
spermatid developmentGO:000728640.014
secretion by cellGO:00329402260.014
reactive oxygen species metabolic processGO:0072593750.014
cell projection assemblyGO:00300311260.014
cell part morphogenesisGO:00329901370.014
single organism carbohydrate metabolic processGO:00447231930.014
interspecies interaction between organismsGO:00444191560.014
peptidyl lysine acetylationGO:00183941010.014
epithelial tube branching involved in lung morphogenesisGO:006044140.014
neurotransmitter secretionGO:000726940.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of gtp catabolic processGO:00331241800.014
endodermal cell fate commitmentGO:000171140.014
positive regulation of neural precursor cell proliferationGO:200017920.014
cellular metal ion homeostasisGO:00068751460.014
positive regulation of cell migrationGO:00303351720.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
protein localization to organelleGO:00333652800.014
endomembrane system organizationGO:00102561960.014
morphogenesis of embryonic epitheliumGO:001633140.014
rhythmic behaviorGO:000762220.014
tripartite regional subdivisionGO:000735120.014
regenerationGO:003109940.014
regulation of secretion by cellGO:19035301770.014
regulation of anatomical structure morphogenesisGO:00226032860.014
regulation of multi organism processGO:00439001570.013
response to radiationGO:00093141510.013
regulation of protein complex assemblyGO:00432541470.013
regulation of cell morphogenesisGO:00226041530.013
intracellular protein transportGO:00068862700.013
osteoblast differentiationGO:0001649920.013
regulation of cytokine productionGO:00018172320.013
monocarboxylic acid metabolic processGO:00327871850.013
regulation of protein catabolic processGO:00421761550.013
embryonic epithelial tube formationGO:000183840.013
actin cytoskeleton organizationGO:00300362070.013
hemopoiesisGO:00300971800.013
regulation of secretionGO:00510461940.013
metencephalon developmentGO:002203720.013
cell morphogenesis involved in differentiationGO:00009041440.013
protein localization to membraneGO:00726571600.013
negative regulation of organelle organizationGO:00106391260.013
ossificationGO:00015031210.013
negative regulation of cell cycle processGO:00109481210.013
positive regulation of cell cycle processGO:00900681060.013
nuclear importGO:00511701060.013
lens development in camera type eyeGO:000208820.013
modification dependent macromolecule catabolic processGO:00436322120.013
negative regulation of phosphorylationGO:00423261740.013
detection of stimulusGO:0051606850.013
organelle fissionGO:00482851490.013
meiotic chromosome segregationGO:004513240.013
regulation of protein stabilityGO:0031647870.013
atp catabolic processGO:00062001570.013
regulation of cell developmentGO:00602841610.013
sensory perception of painGO:001923340.013
positive regulation of cell deathGO:00109422630.013
endosomal transportGO:00161971290.013
cellular ion homeostasisGO:00068731680.013
prostate gland developmentGO:003085030.013
microtubule cytoskeleton organizationGO:00002261760.013
ameboidal type cell migrationGO:00016671350.013
rna processingGO:00063962550.013
forebrain neuron differentiationGO:002187930.013
regulation of cell growthGO:00015581350.013
regulation of peptidase activityGO:00525471800.013
protein localization to nucleusGO:00345041360.013
regulation of phosphatase activityGO:0010921810.012
positive regulation of protein kinase activityGO:00458601900.012
regulation of protein maturationGO:19033171500.012
regulation of cell adhesionGO:00301551660.012
tissue regenerationGO:004224630.012
protein oligomerizationGO:00512591730.012
regulation of translationGO:0006417890.012
telomere maintenance via telomere lengtheningGO:001083390.012
nerve developmentGO:002167540.012
cellular response to lipidGO:00713961270.012
modification dependent protein catabolic processGO:00199412090.012
positive regulation of organelle organizationGO:00106381950.012
positive regulation of cell motilityGO:20001471770.012
immune system developmentGO:00025201950.012
response to fungusGO:000962040.012
response to woundingGO:00096111680.012
embryo developmentGO:00097901230.012
cell divisionGO:00513011680.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
carboxylic acid biosynthetic processGO:0046394970.012
ubiquitin dependent protein catabolic processGO:00065112060.012
neuron differentiationGO:00301821380.012
endochondral bone morphogenesisGO:006035030.012
negative regulation of phosphatase activityGO:0010923610.012
positive regulation of developmental processGO:00510943140.012
motor neuron axon guidanceGO:000804520.012
chemotaxisGO:00069351570.012
regulation of rho gtpase activityGO:0032319660.012
multi organism cellular processGO:00447641560.012
circadian behaviorGO:004851220.012
negative regulation of cell growthGO:0030308830.012
response to lipidGO:00339932060.012
endocytosisGO:00068971590.012
syncytium formation by plasma membrane fusionGO:000076820.012
organelle assemblyGO:00709251760.012
divalent inorganic cation homeostasisGO:00725071360.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
chromosome segregationGO:00070591140.012
cellular response to growth factor stimulusGO:00713631970.012
proteasomal protein catabolic processGO:00104981760.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of defense responseGO:00313471540.012
regulation of response to external stimulusGO:00321012220.012
photoreceptor cell differentiationGO:004653020.012
positive regulation of kinase activityGO:00336742040.012
reactive nitrogen species metabolic processGO:200105730.012
regulation of cell activationGO:00508651250.012
positive regulation of immune system processGO:00026842830.012
positive regulation of cellular component biogenesisGO:00440891580.012
cell cell signalingGO:00072671550.012
Fly
mitotic nuclear divisionGO:00070671190.012
response to axon injuryGO:004867810.012
response to inorganic substanceGO:00100351270.011
stem cell divisionGO:001714520.011
peptidyl tyrosine modificationGO:00182121700.011
positive regulation of cell developmentGO:0010720920.011
viral life cycleGO:00190581320.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
regulation of actin cytoskeleton organizationGO:00329561160.011
long term memoryGO:000761620.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of protein processingGO:00706131500.011
methylationGO:00322591060.011
sensory perceptionGO:00076001030.011
cell cycle checkpointGO:00000751170.011
agingGO:0007568660.011
receptor metabolic processGO:0043112810.011
regulation of immune responseGO:00507762010.011
divalent inorganic cation transportGO:00725111580.011
blood vessel morphogenesisGO:00485141620.011
epithelial cell migrationGO:00106311190.011
alcohol metabolic processGO:00060661140.011
neuron projection developmentGO:00311751060.011
organic anion transportGO:00157111030.011
rna catabolic processGO:0006401710.011
neuron fate commitmentGO:004866320.011
negative regulation of signal transduction in absence of ligandGO:1901099160.011
single organism cell adhesionGO:00986021790.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
blood vessel developmentGO:00015681720.011
cell substrate adhesionGO:00315891320.011
calcium ion transportGO:00068161470.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
regulation of male gonad developmentGO:200001840.011
negative regulation of gliogenesisGO:001401430.011
positive regulation of mapk cascadeGO:00434101900.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
negative regulation of growthGO:0045926970.011
positive regulation of proteolysisGO:00458621420.011
regulation of protein transportGO:00512232130.011
rna dependent dna replicationGO:0006278160.011
regulation of epithelial cell migrationGO:0010632930.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of transportGO:00510511760.011
negative regulation of protein processingGO:00109551420.011
negative regulation of immune system processGO:00026831360.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
limbic system developmentGO:002176130.011
regulation of leukocyte activationGO:00026941150.011
cardiac muscle cell contractionGO:008600340.011
regulation of cellular response to stressGO:00801352440.011
protein stabilizationGO:0050821640.011
negative regulation of synaptic transmissionGO:005080520.011
ectodermal placode developmentGO:007169610.011
tube morphogenesisGO:0035239950.011
reactive oxygen species biosynthetic processGO:190340940.011
cerebellum developmentGO:002154920.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
positive regulation of synaptic transmissionGO:005080640.011
regulation of chromosome organizationGO:00330441030.011
meiosis iGO:000712740.011
cytokine productionGO:00018162470.011
regulation of homeostatic processGO:00328441210.011
sequestering of metal ionGO:0051238240.010
regulation of synaptic plasticityGO:004816730.010
canonical wnt signaling pathwayGO:00600701160.010
angiogenesisGO:00015251470.010
positive regulation of intracellular transportGO:00323881040.010
g1 s transition of mitotic cell cycleGO:0000082780.010
i kappab kinase nf kappab signalingGO:00072491660.010
single organism nuclear importGO:19025931040.010
regulation of bindingGO:00510981110.010
neural tube formationGO:000184130.010
organic hydroxy compound metabolic processGO:19016151470.010
generation of neuronsGO:00486991520.010
regulation of dna metabolic processGO:00510521530.010
tissue migrationGO:00901301190.010
nucleotide biosynthetic processGO:00091651090.010
visual behaviorGO:000763220.010
positive regulation of immune responseGO:00507781590.010
neural tube closureGO:000184330.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
regulation of metal ion transportGO:00109591200.010
positive regulation of apoptotic processGO:00430652460.010
negative regulation of wnt signaling pathwayGO:0030178690.010
establishment of protein localization to membraneGO:00901501210.010
primary neural tube formationGO:001402030.010
endodermal cell fate specificationGO:000171440.010
regulation of vesicle mediated transportGO:00606271300.010
protein autophosphorylationGO:00467771230.010
actin mediated cell contractionGO:0070252120.010
blood circulationGO:00080151130.010
regulation of meiotic cell cycleGO:005144540.010

SMG6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.183
disease of cellular proliferationDOID:145661740.183
organ system cancerDOID:00506861640.081
sensory system diseaseDOID:00501552030.036
nervous system diseaseDOID:8634310.036
eye and adnexa diseaseDOID:14921500.027
eye diseaseDOID:56141490.027
disease of metabolismDOID:00146672950.024
musculoskeletal system diseaseDOID:172230.021
inherited metabolic disorderDOID:6552420.020
central nervous system diseaseDOID:3311860.016
cardiovascular system diseaseDOID:12871060.015
immune system cancerDOID:0060083360.015
hematologic cancerDOID:2531360.015
connective tissue diseaseDOID:651090.014
muscle tissue diseaseDOID:661130.012
myopathyDOID:4231040.012
muscular diseaseDOID:00800001140.012
immune system diseaseDOID:29141550.012
myeloid leukemiaDOID:8692180.011
leukemiaDOID:1240210.011
acute myeloid leukemiaDOID:9119170.011
brain diseaseDOID:936730.011
retinal diseaseDOID:56791180.010