Homo sapiens

59 known processes

SMG1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

(Aliases: KIAA0421,61E3.4,LIP,ATX)

SMG1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mrna catabolic processGO:0006402561.000
mrna metabolic processGO:00160711750.999
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.999
rna catabolic processGO:0006401710.998
nuclear transcribed mrna catabolic processGO:0000956480.998
cellular macromolecule catabolic processGO:00442653800.991
male genitalia developmentGO:003053910.948
Worm
histone mrna catabolic processGO:0071044100.434
protein ubiquitinationGO:00165673140.386
translationGO:00064121320.341
chromatin organizationGO:00063253510.314
cellular ketone metabolic processGO:0042180800.292
protein modification by small protein conjugationGO:00324463420.287
sex differentiationGO:0007548450.276
Worm
regulation of cellular ketone metabolic processGO:0010565500.251
reproductive processGO:00224141060.246
Worm
purine nucleoside triphosphate metabolic processGO:00091444120.237
female gamete generationGO:000729220.234
purine nucleoside catabolic processGO:00061523980.224
amine metabolic processGO:0009308440.195
cellular amine metabolic processGO:0044106410.174
positive regulation of cellular amino acid metabolic processGO:004576430.172
cellular response to dna damage stimulusGO:00069743790.168
enzyme linked receptor protein signaling pathwayGO:00071673030.158
regulation of cellular amino acid metabolic processGO:000652160.149
rna processingGO:00063962550.149
purine ribonucleoside metabolic processGO:00461284370.138
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.138
ribonucleoprotein complex biogenesisGO:00226131160.134
cellular amino acid metabolic processGO:00065201160.132
methylationGO:00322591060.131
purine nucleotide catabolic processGO:00061954050.131
regulation of mrna processingGO:0050684480.127
mrna processingGO:00063971330.126
rna phosphodiester bond hydrolysisGO:0090501350.125
macromolecule methylationGO:0043414970.120
cellular macromolecular complex assemblyGO:00346223240.115
gonad developmentGO:0008406340.114
Worm
oogenesisGO:004847720.113
multicellular organismal agingGO:001025930.111
dna repairGO:00062811980.110
regulation of cellular amine metabolic processGO:0033238110.106
single organism reproductive processGO:0044702980.103
Worm
segmentationGO:003528240.100
telomere maintenanceGO:0000723320.099
reproductive system developmentGO:0061458560.097
Worm
positive regulation of cellular amine metabolic processGO:003324070.096
nucleoside phosphate catabolic processGO:19012924120.094
organophosphate catabolic processGO:00464344300.092
anatomical structure homeostasisGO:00602491000.084
developmental process involved in reproductionGO:0003006660.078
Worm
intracellular mrna localizationGO:000829810.078
regulation of establishment of protein localizationGO:00702012420.077
blastoderm segmentationGO:000735020.077
negative regulation of transportGO:00510511760.076
determination of adult lifespanGO:000834020.076
peptidyl serine phosphorylationGO:00181051010.074
regulation of cellular component biogenesisGO:00440872810.074
reactive oxygen species biosynthetic processGO:190340940.073
reproductive structure developmentGO:0048608550.073
Worm
negative regulation of cellular amine metabolic processGO:003323930.073
positive regulation of translationGO:0045727350.072
mapk cascadeGO:00001652880.072
signal transduction by phosphorylationGO:00230142970.072
organ morphogenesisGO:00098871470.071
regulation of protein kinase activityGO:00458592890.071
embryonic organ developmentGO:0048568360.070
atp metabolic processGO:00460341760.069
negative regulation of cellular amino acid metabolic processGO:004576320.068
ribonucleoprotein complex subunit organizationGO:0071826810.066
positive regulation of phosphorylationGO:00423273940.064
response to organic cyclic compoundGO:00140702040.061
negative regulation of cell deathGO:00605483450.061
microtubule cytoskeleton organizationGO:00002261760.060
regulation of cell developmentGO:00602841610.059
vesicle mediated transportGO:00161923710.058
Fly
regulation of kinase activityGO:00435493140.058
single organism cellular localizationGO:19025803320.057
nucleoside catabolic processGO:00091644080.056
regulation of translationGO:0006417890.056
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.055
nucleic acid phosphodiester bond hydrolysisGO:00903051020.053
positive regulation of apoptotic processGO:00430652460.053
regulation of cellular response to stressGO:00801352440.053
purine ribonucleoside catabolic processGO:00461303980.052
regulation of protein transportGO:00512232130.052
regulation of protein localizationGO:00328802960.051
negative regulation of programmed cell deathGO:00430693210.049
regulation of cell differentiationGO:00455953930.049
ribonucleoside monophosphate metabolic processGO:00091611870.048
regulation of cell maturationGO:190342930.048
dosage compensationGO:000754930.048
erk1 and erk2 cascadeGO:00703711040.047
rna splicingGO:00083801310.047
positive regulation of erk1 and erk2 cascadeGO:0070374750.047
odontogenesisGO:0042476250.047
negative regulation of apoptotic processGO:00430663160.047
regulation of transferase activityGO:00513383550.046
positive regulation of kinase activityGO:00336742040.046
cellular response to endogenous stimulusGO:00714953360.045
chromatin modificationGO:00165682980.045
negative regulation of cellular protein metabolic processGO:00322693530.044
post embryonic developmentGO:000979120.044
purine ribonucleoside triphosphate catabolic processGO:00092073910.043
negative regulation of hydrolase activityGO:00513461820.043
purine nucleoside monophosphate metabolic processGO:00091261860.043
protein localization to organelleGO:00333652800.043
regulation of cellular component movementGO:00512703340.043
immune responseGO:00069553070.042
regulation of protein complex assemblyGO:00432541470.042
negative regulation of catalytic activityGO:00430863350.042
positive regulation of cellular catabolic processGO:00313312840.041
purine nucleoside monophosphate catabolic processGO:00091281580.041
purine ribonucleotide catabolic processGO:00091544040.041
positive regulation of mapk cascadeGO:00434101900.040
response to oxygen containing compoundGO:19017003690.040
reactive nitrogen species metabolic processGO:200105730.039
positive regulation of protein phosphorylationGO:00019343130.038
anterior posterior axis specificationGO:000994820.038
regulation of mapk cascadeGO:00434082620.037
t cell homeostasisGO:004302930.037
regulation of reactive oxygen species biosynthetic processGO:190342630.037
cellular response to organic cyclic compoundGO:00714071270.037
negative regulation of endopeptidase activityGO:0010951840.037
atp catabolic processGO:00062001570.037
positive regulation of response to dna damage stimulusGO:2001022430.037
lymphocyte homeostasisGO:000226040.035
rna interferenceGO:001624640.035
regulation of cell cycleGO:00517263930.035
nucleoside triphosphate metabolic processGO:00091414220.035
actin filament based processGO:00300292240.034
response to lipidGO:00339932060.033
regulation of response to dna damage stimulusGO:2001020940.033
cytokinesisGO:0000910960.033
peptidyl tyrosine modificationGO:00182121700.033
histone h3 acetylationGO:0043966450.032
purine ribonucleoside monophosphate metabolic processGO:00091671860.032
defense responseGO:00069523150.031
cell developmentGO:00484683280.031
positive regulation of cellular component organizationGO:00511303760.031
histone modificationGO:00165702510.031
neural tube formationGO:000184130.030
rna 3 end processingGO:0031123350.030
negative regulation of peptidase activityGO:0010466910.030
dna recombinationGO:0006310770.030
posttranscriptional gene silencingGO:0016441250.030
regulation of mrna metabolic processGO:1903311530.030
regulation of proteolysisGO:00301622930.030
purine containing compound catabolic processGO:00725234110.030
oxidation reduction processGO:00551143960.029
embryo developmentGO:00097901230.029
development of primary sexual characteristicsGO:0045137350.029
Worm
positive regulation of immune system processGO:00026842830.029
morphogenesis of embryonic epitheliumGO:001633140.028
nucleoside monophosphate metabolic processGO:00091231910.028
ribonucleoside catabolic processGO:00424544060.028
dna dependent dna replicationGO:0006261440.028
peptidyl serine modificationGO:00182091060.027
circulatory system developmentGO:00723592620.027
neuromuscular junction developmentGO:000752830.027
positive regulation of transportGO:00510503360.027
regulation of anatomical structure morphogenesisGO:00226032860.027
gene silencing by rnaGO:0031047260.027
embryonic epithelial tube formationGO:000183840.027
protein localization to nucleusGO:00345041360.027
agingGO:0007568660.027
positive regulation of cell proliferationGO:00082843010.027
cellular response to nitrogen compoundGO:19016991440.027
central nervous system developmentGO:00074171230.026
positive regulation of catabolic processGO:00098963100.026
ribonucleoprotein complex assemblyGO:0022618780.026
regulation of intracellular protein transportGO:00331571230.026
nucleus localizationGO:005164710.026
positive regulation of gliogenesisGO:001401540.026
positive regulation of transferase activityGO:00513472270.026
nucleoside triphosphate catabolic processGO:00091433940.026
ras protein signal transductionGO:0007265730.025
heart developmentGO:0007507950.025
negative regulation of protein modification processGO:00314002000.025
positive regulation of cell motilityGO:20001471770.025
dephosphorylationGO:00163112090.025
positive regulation of programmed cell deathGO:00430682490.025
dna templated transcription initiationGO:0006352350.024
negative regulation of intracellular signal transductionGO:19025321830.024
covalent chromatin modificationGO:00165692540.024
response to abiotic stimulusGO:00096283360.024
positive regulation of immune responseGO:00507781590.024
neuroblast proliferationGO:000740540.024
anatomical structure formation involved in morphogenesisGO:00486462840.024
regulation of intracellular transportGO:00323861950.023
cell activationGO:00017752130.023
positive regulation of protein kinase activityGO:00458601900.023
endothelial cell apoptotic processGO:0072577260.023
regulation of immune responseGO:00507762010.023
negative regulation of phosphorus metabolic processGO:00105632670.023
ribonucleoside triphosphate metabolic processGO:00091994120.022
regulation of gene expression epigeneticGO:0040029730.022
regulation of erk1 and erk2 cascadeGO:0070372990.022
organic hydroxy compound metabolic processGO:19016151470.022
regulation of carbohydrate metabolic processGO:0006109540.022
nucleocytoplasmic transportGO:00069131760.022
photoreceptor cell differentiationGO:004653020.022
glycosyl compound catabolic processGO:19016584130.022
ion transmembrane transportGO:00342203380.021
positive regulation of locomotionGO:00400171860.021
neural nucleus developmentGO:0048857470.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
peptidyl tyrosine phosphorylationGO:00181081700.021
regulation of cell divisionGO:00513021160.021
immune response regulating signaling pathwayGO:0002764970.021
positive regulation of protein serine threonine kinase activityGO:00719021190.020
protein importGO:00170381300.020
dna replicationGO:00062601160.020
embryonic morphogenesisGO:0048598850.020
fat cell differentiationGO:0045444320.020
cardiovascular system developmentGO:00723582620.020
nucleoside monophosphate catabolic processGO:00091251590.020
chromatin assembly or disassemblyGO:0006333780.020
oocyte differentiationGO:000999420.020
lipid biosynthetic processGO:00086101770.020
posttranscriptional regulation of gene expressionGO:00106082130.020
response to external biotic stimulusGO:00432072610.020
regulation of locomotionGO:00400123290.020
positive regulation of reactive oxygen species biosynthetic processGO:190342820.020
negative regulation of phosphate metabolic processGO:00459362670.020
monosaccharide metabolic processGO:0005996740.020
regulation of protein processingGO:00706131500.020
negative regulation of phosphorylationGO:00423261740.019
positive regulation of cellular component movementGO:00512721810.019
hindbrain developmentGO:003090230.019
organonitrogen compound biosynthetic processGO:19015662000.019
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.019
regulation of defense responseGO:00313471540.019
small gtpase mediated signal transductionGO:0007264780.019
protein methylationGO:0006479740.019
regulation of neurotransmitter secretionGO:004692830.019
positive regulation of transporter activityGO:0032411320.019
nucleotide catabolic processGO:00091664080.019
plasma membrane organizationGO:00070091150.019
positive regulation of organelle organizationGO:00106381950.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
immune system developmentGO:00025201950.018
single organism nuclear importGO:19025931040.018
negative regulation of proteolysisGO:00458611320.018
establishment of protein localization to organelleGO:00725941720.018
behaviorGO:00076101120.018
positive regulation of superoxide anion generationGO:003293040.018
protein catabolic processGO:00301633250.018
regulation of cytoskeleton organizationGO:00514931770.018
response to hormoneGO:00097251750.018
regulation of peptidyl tyrosine phosphorylationGO:00507301080.018
regulation of cell migrationGO:00303342890.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
reactive oxygen species metabolic processGO:0072593750.017
anterior posterior axis specification embryoGO:000859520.017
peptidyl lysine modificationGO:00182051440.017
negative regulation of protein processingGO:00109551420.017
nuclear transportGO:00511691790.017
oocyte developmentGO:004859910.017
regulation of bindingGO:00510981110.017
regulation of cytoplasmic transportGO:19036491490.017
regulation of protein stabilityGO:0031647870.017
regulation of map kinase activityGO:00434051080.017
negative regulation of protein maturationGO:19033181420.017
cellular response to oxygen containing compoundGO:19017012760.017
phospholipid metabolic processGO:0006644990.017
positive regulation of cell migrationGO:00303351720.017
regenerationGO:003109940.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
mitotic cell cycleGO:00002783260.017
posttranscriptional gene silencing by rnaGO:0035194250.017
meiotic chromosome segregationGO:004513240.017
eye photoreceptor cell differentiationGO:000175420.017
actin cytoskeleton organizationGO:00300362070.017
proteolysis involved in cellular protein catabolic processGO:00516032440.016
intracellular protein transportGO:00068862700.016
locomotory behaviorGO:000762610.016
establishment of organelle localizationGO:0051656590.016
Fly
mitotic cell cycle phase transitionGO:00447721620.016
ribonucleotide catabolic processGO:00092614050.016
protein processingGO:00164852260.016
tube morphogenesisGO:0035239950.016
positive regulation of cell deathGO:00109422630.016
actin filament organizationGO:00070151280.016
cellular response to lipidGO:00713961270.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
rna localizationGO:0006403410.016
protein maturationGO:00516042330.016
regulation of cell motilityGO:20001452990.016
regulation of dna metabolic processGO:00510521530.016
internal peptidyl lysine acetylationGO:0018393970.016
reproductionGO:0000003630.015
regulation of blood vessel endothelial cell migrationGO:0043535300.015
regulation of transporter activityGO:0032409820.015
regulation of protein targetingGO:1903533910.015
positive regulation of cellular component biogenesisGO:00440891580.015
regulation of protein serine threonine kinase activityGO:00719001790.015
leukocyte activationGO:00453211640.015
immune effector processGO:00022521590.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.015
hemopoiesisGO:00300971800.015
negative regulation of cell proliferationGO:00082852280.015
dna packagingGO:0006323770.015
response to radiationGO:00093141510.015
head developmentGO:00603221080.015
gene silencingGO:0016458490.015
regulation of endopeptidase activityGO:00525481700.015
macromolecular complex disassemblyGO:0032984600.015
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.015
immune response activating signal transductionGO:0002757900.015
response to salt stressGO:000965130.015
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.014
protein acetylationGO:00064731160.014
lipid metabolic processGO:00066293810.014
regulation of protein import into nucleusGO:0042306780.014
epithelium developmentGO:00604292270.014
regulation of protein maturationGO:19033171500.014
spermatid differentiationGO:004851540.014
axis elongationGO:000340140.014
activation of protein kinase activityGO:0032147900.014
cellular lipid metabolic processGO:00442553030.014
ameboidal type cell migrationGO:00016671350.014
regulation of dephosphorylationGO:0035303960.014
receptor mediated endocytosisGO:0006898840.014
regulation of immune effector processGO:0002697910.014
epithelium migrationGO:00901321190.014
epithelial cell migrationGO:00106311190.014
histone lysine methylationGO:0034968500.014
pattern specification processGO:0007389430.014
endomembrane system organizationGO:00102561960.014
hexose metabolic processGO:0019318550.013
nuclear migrationGO:000709710.013
positive regulation of dna metabolic processGO:0051054730.013
mitotic cell cycle processGO:19030472860.013
microtubule based processGO:00070172100.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
alcohol metabolic processGO:00060661140.013
epithelial cell proliferationGO:00506731280.013
intracellular receptor signaling pathwayGO:00305221040.013
skeletal system developmentGO:0001501790.013
organelle fissionGO:00482851490.013
modification dependent macromolecule catabolic processGO:00436322120.013
double strand break repair via homologous recombinationGO:0000724500.013
innate immune responseGO:00450871780.013
tor signalingGO:0031929390.013
cell morphogenesisGO:00009022960.013
neurological system processGO:00508771630.013
positive regulation of developmental processGO:00510943140.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
protein deubiquitinationGO:0016579790.013
negative regulation of cellular component organizationGO:00511292350.013
response to woundingGO:00096111680.013
single organism membrane organizationGO:00448022680.013
positive regulation of cell growthGO:0030307480.012
regulation of nucleocytoplasmic transportGO:0046822980.012
organelle assemblyGO:00709251760.012
regulation of protein catabolic processGO:00421761550.012
negative regulation of catabolic processGO:00098951040.012
cellular protein complex disassemblyGO:0043624360.012
negative regulation of protein ubiquitinationGO:0031397350.012
negative regulation of plasma membrane long chain fatty acid transportGO:001074840.012
negative regulation of immune system processGO:00026831360.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of rna splicingGO:0043484620.012
regulation of peptidyl serine phosphorylationGO:0033135500.012
cellular response to hormone stimulusGO:00328701250.012
cell type specific apoptotic processGO:00972851250.012
regulation of endothelial cell migrationGO:0010594670.012
negative regulation of lipid metabolic processGO:0045833380.012
dna conformation changeGO:00711031130.012
peptidyl lysine acetylationGO:00183941010.012
monocarboxylic acid metabolic processGO:00327871850.012
nervous system developmentGO:00073992930.012
neurotransmitter secretionGO:000726940.012
regulation of neuron differentiationGO:0045664700.012
regulation of response to external stimulusGO:00321012220.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
nuclear importGO:00511701060.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
transmembrane transportGO:00550853990.011
epithelial tube morphogenesisGO:0060562380.011
spermatid developmentGO:000728640.011
endothelial cell migrationGO:0043542860.011
positive regulation of peptidyl serine phosphorylationGO:0033138420.011
protein targeting to nucleusGO:00447441040.011
negative regulation of mapk cascadeGO:0043409560.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
regulation of cell growthGO:00015581350.011
carbohydrate metabolic processGO:00059752070.011
maintenance of cell polarityGO:003001120.011
neurogenesisGO:00220081690.011
cell projection organizationGO:00300302520.011
carbohydrate biosynthetic processGO:0016051420.011
negative regulation of protein transportGO:0051224750.011
tripartite regional subdivisionGO:000735120.011
tissue migrationGO:00901301190.011
regulation of nucleotide metabolic processGO:00061402690.011
regulation of lipid biosynthetic processGO:0046890470.011
regulation of multi organism processGO:00439001570.011
regulation of synaptic vesicle exocytosisGO:200030020.011
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.011
negative regulation of intracellular protein transportGO:0090317420.011
cellular response to radiationGO:0071478650.011
organic acid catabolic processGO:0016054710.011
defense response to other organismGO:00985421290.011
nuclear transcribed mrna catabolic process exonucleolyticGO:000029170.011
brain developmentGO:0007420970.011
regulation of apoptotic signaling pathwayGO:20012331750.011
cytokine productionGO:00018162470.011
positive regulation of lipid biosynthetic processGO:0046889220.011
protein dna complex subunit organizationGO:0071824800.010
lens development in camera type eyeGO:000208820.010
positive regulation of lipid metabolic processGO:0045834500.010
mrna 3 end processingGO:0031124240.010
membrane lipid biosynthetic processGO:0046467270.010
positive regulation of protein complex assemblyGO:0031334860.010
chemical homeostasisGO:00488783060.010
peptidyl threonine phosphorylationGO:0018107410.010
cellular component morphogenesisGO:00329893140.010
nucleosome organizationGO:0034728660.010
regulation of protein ubiquitinationGO:0031396950.010
nucleosome assemblyGO:0006334500.010
regulation of transmembrane transportGO:00347621390.010
cellular amide metabolic processGO:0043603690.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
regulation of nucleoside metabolic processGO:00091182090.010
regulation of growthGO:00400081650.010

SMG1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.013
sensory system diseaseDOID:00501552030.011
nervous system diseaseDOID:8634310.011