Homo sapiens

8 known processes

HMBS

hydroxymethylbilane synthase

(Aliases: PORC,PBG-D,UPS,PBGD)

HMBS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.158
cellular amino acid metabolic processGO:00065201160.121
mitochondrion organizationGO:00070051560.095
cofactor metabolic processGO:0051186870.084
carbohydrate derivative biosynthetic processGO:19011372070.058
cellular ketone metabolic processGO:0042180800.057
cytoplasmic transportGO:00164823790.049
multicellular organismal agingGO:001025930.045
purine ribonucleoside metabolic processGO:00461284370.043
single organism cellular localizationGO:19025803320.042
posttranscriptional regulation of gene expressionGO:00106082130.041
nucleotide biosynthetic processGO:00091651090.040
regulation of cellular amino acid metabolic processGO:000652160.039
regulation of cellular amine metabolic processGO:0033238110.039
organonitrogen compound biosynthetic processGO:19015662000.038
locomotory behaviorGO:000762610.038
protein processingGO:00164852260.038
cellular amine metabolic processGO:0044106410.036
protein maturationGO:00516042330.033
cellular macromolecule catabolic processGO:00442653800.031
small molecule biosynthetic processGO:00442831570.030
determination of adult lifespanGO:000834020.030
organophosphate catabolic processGO:00464344300.030
regulation of proteolysisGO:00301622930.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
amine metabolic processGO:0009308440.030
cellular response to dna damage stimulusGO:00069743790.030
female gamete generationGO:000729220.029
positive regulation of catabolic processGO:00098963100.029
negative regulation of cell proliferationGO:00082852280.028
single organism membrane organizationGO:00448022680.028
organophosphate biosynthetic processGO:00904071630.027
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.026
cellular lipid metabolic processGO:00442553030.024
positive regulation of cellular amine metabolic processGO:003324070.024
cellular response to oxygen containing compoundGO:19017012760.024
regulation of cellular ketone metabolic processGO:0010565500.024
cellular macromolecular complex assemblyGO:00346223240.024
alcohol metabolic processGO:00060661140.024
regulation of cellular response to stressGO:00801352440.024
defense responseGO:00069523150.023
nucleoside phosphate biosynthetic processGO:19012931090.023
nucleoside triphosphate metabolic processGO:00091414220.023
ribonucleotide catabolic processGO:00092614050.023
negative regulation of cellular protein metabolic processGO:00322693530.023
mitotic cell cycle phase transitionGO:00447721620.022
embryo developmentGO:00097901230.022
chemical homeostasisGO:00488783060.022
negative regulation of programmed cell deathGO:00430693210.022
response to biotic stimulusGO:00096072760.022
cofactor biosynthetic processGO:0051188310.021
response to growth factorGO:00708482050.021
negative regulation of protein metabolic processGO:00512483910.021
protein homooligomerizationGO:00512601000.021
response to oxygen containing compoundGO:19017003690.020
protein localization to organelleGO:00333652800.020
regulation of transferase activityGO:00513383550.020
organelle assemblyGO:00709251760.020
protein localization to membraneGO:00726571600.020
protein targetingGO:00066051870.019
nucleocytoplasmic transportGO:00069131760.019
positive regulation of hydrolase activityGO:00513453310.019
apoptotic signaling pathwayGO:00971902680.019
oogenesisGO:004847720.019
protein oligomerizationGO:00512591730.018
negative regulation of protein maturationGO:19033181420.018
regulation of kinase activityGO:00435493140.018
regulation of endopeptidase activityGO:00525481700.018
neuromuscular junction developmentGO:000752830.018
regulation of cell growthGO:00015581350.018
response to organic cyclic compoundGO:00140702040.018
protein catabolic processGO:00301633250.018
positive regulation of developmental processGO:00510943140.018
negative regulation of phosphorylationGO:00423261740.017
regulation of peptidase activityGO:00525471800.017
positive regulation of cellular catabolic processGO:00313312840.017
response to abiotic stimulusGO:00096283360.017
negative regulation of catalytic activityGO:00430863350.017
negative regulation of protein phosphorylationGO:00019331400.017
immune responseGO:00069553070.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
amino acid activationGO:0043038120.017
histone modificationGO:00165702510.016
negative regulation of peptidase activityGO:0010466910.016
establishment of protein localization to organelleGO:00725941720.016
actin filament based processGO:00300292240.016
adult locomotory behaviorGO:000834410.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
nucleoside phosphate catabolic processGO:19012924120.016
ribonucleoside triphosphate catabolic processGO:00092033910.016
regulation of defense responseGO:00313471540.016
positive regulation of cellular component organizationGO:00511303760.016
dna repairGO:00062811980.016
cell morphogenesisGO:00009022960.015
internal peptidyl lysine acetylationGO:0018393970.015
regulation of cell differentiationGO:00455953930.015
maintenance of locationGO:00512351120.015
ribonucleoside triphosphate metabolic processGO:00091994120.015
positive regulation of proteolysisGO:00458621420.015
negative regulation of multicellular organismal processGO:00512413170.015
cell growthGO:00160491600.015
negative regulation of developmental processGO:00510932470.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of protein processingGO:00706131500.014
epithelium developmentGO:00604292270.014
negative regulation of organelle organizationGO:00106391260.014
positive regulation of immune system processGO:00026842830.014
guanosine containing compound metabolic processGO:19010682440.014
response to external biotic stimulusGO:00432072610.014
microtubule based processGO:00070172100.014
negative regulation of cellular component organizationGO:00511292350.014
protein import into mitochondrial inner membraneGO:004503930.014
lipid metabolic processGO:00066293810.014
cellular homeostasisGO:00197251960.014
nucleoside monophosphate metabolic processGO:00091231910.014
carbohydrate metabolic processGO:00059752070.014
negative regulation of growthGO:0045926970.014
membrane organizationGO:00610242920.014
purine ribonucleotide biosynthetic processGO:0009152790.014
cellular component morphogenesisGO:00329893140.014
cellular protein catabolic processGO:00442572610.014
trna aminoacylation for mitochondrial protein translationGO:007012730.013
positive regulation of transportGO:00510503360.013
glycosylationGO:0070085710.013
cellular response to organic cyclic compoundGO:00714071270.013
regulation of mitochondrion organizationGO:0010821540.013
purine containing compound catabolic processGO:00725234110.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
spermatid developmentGO:000728640.013
internal protein amino acid acetylationGO:00064751010.013
anterior posterior axis specificationGO:000994820.013
cellular protein complex assemblyGO:00436231880.013
regulation of immune responseGO:00507762010.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
rna interferenceGO:001624640.013
purine nucleoside catabolic processGO:00061523980.013
mitotic cell cycle processGO:19030472860.013
negative regulation of phosphorus metabolic processGO:00105632670.013
glycosyl compound catabolic processGO:19016584130.013
mitotic cell cycleGO:00002783260.013
alpha amino acid metabolic processGO:1901605720.013
regulation of protein kinase activityGO:00458592890.013
negative regulation of hydrolase activityGO:00513461820.013
positive regulation of purine nucleotide metabolic processGO:19005442270.012
regulation of apoptotic signaling pathwayGO:20012331750.012
nucleotide catabolic processGO:00091664080.012
dna conformation changeGO:00711031130.012
regulation of nucleoside metabolic processGO:00091182090.012
negative regulation of protein modification processGO:00314002000.012
negative regulation of proteolysisGO:00458611320.012
segmentationGO:003528240.012
defense response to other organismGO:00985421290.012
ion homeostasisGO:00508012300.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
regulation of protein maturationGO:19033171500.012
spermatid differentiationGO:004851540.012
vesicle mediated transportGO:00161923710.012
peptidyl serine modificationGO:00182091060.011
positive regulation of nucleoside metabolic processGO:00459791860.011
microtubule organizing center organizationGO:0031023620.011
peptidyl lysine modificationGO:00182051440.011
negative regulation of cell cycleGO:00457861930.011
intracellular protein transportGO:00068862700.011
single organism carbohydrate metabolic processGO:00447231930.011
cell projection assemblyGO:00300311260.011
myosin filament assemblyGO:003103420.011
regulation of translationGO:0006417890.011
negative regulation of phosphate metabolic processGO:00459362670.011
glutamine family amino acid metabolic processGO:0009064170.011
response to oxidative stressGO:00069791210.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
negative regulation of protein processingGO:00109551420.011
regulation of protein stabilityGO:0031647870.011
cell activationGO:00017752130.011
negative regulation of immune system processGO:00026831360.011
positive regulation of cell differentiationGO:00455972110.011
blastoderm segmentationGO:000735020.011
cellular ion homeostasisGO:00068731680.011
regulation of cell cycle phase transitionGO:19019871260.010
metal ion transportGO:00300012720.010
cytokine productionGO:00018162470.010
protein tetramerizationGO:0051262470.010
organic hydroxy compound metabolic processGO:19016151470.010
establishment of protein localization to membraneGO:00901501210.010
protein acylationGO:00435431380.010
cell type specific apoptotic processGO:00972851250.010
fatty acid metabolic processGO:00066311150.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
protein acetylationGO:00064731160.010
sulfate transmembrane transportGO:190235830.010
response to virusGO:00096151260.010
response to nitrogen compoundGO:19016981840.010
growthGO:00400072020.010

HMBS disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.877
inherited metabolic disorderDOID:6552420.877
amino acid metabolic disorderDOID:9252500.027
carbohydrate metabolic disorderDOID:2978550.018
central nervous system diseaseDOID:3311860.013
nervous system diseaseDOID:8634310.013
neurodegenerative diseaseDOID:12891020.013
cancerDOID:1621670.011
disease of cellular proliferationDOID:145661740.011
porphyriaDOID:1326880.001
acute porphyriaDOID:313370.001