| histone modification | GO:0016570 | 251 | 0.565 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.393 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.308 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.224 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.213 | |
| internal protein amino acid acetylation | GO:0006475 | 101 | 0.209 | |
| chromatin organization | GO:0006325 | 351 | 0.207 | |
| chromatin modification | GO:0016568 | 298 | 0.200 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.171 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.167 | |
| peptidyl lysine acetylation | GO:0018394 | 101 | 0.166 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.164 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.135 | |
| protein ubiquitination | GO:0016567 | 314 | 0.134 | |
| macromolecule methylation | GO:0043414 | 97 | 0.133 | |
| amine metabolic process | GO:0009308 | 44 | 0.127 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.127 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.124 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.124 | |
| internal peptidyl lysine acetylation | GO:0018393 | 97 | 0.118 | |
| histone acetylation | GO:0016573 | 93 | 0.108 | |
| dna templated transcription initiation | GO:0006352 | 35 | 0.107 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.104 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.100 | |
| mrna metabolic process | GO:0016071 | 175 | 0.098 | Rat |
| histone h4 acetylation | GO:0043967 | 47 | 0.089 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.087 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.085 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.071 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.068 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 54 | 0.068 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.066 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.066 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.061 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.061 | |
| histone lysine methylation | GO:0034968 | 50 | 0.060 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.060 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.059 | |
| rna processing | GO:0006396 | 255 | 0.059 | Rat |
| negative regulation of cell death | GO:0060548 | 345 | 0.057 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.057 | |
| behavioral response to ethanol | GO:0048149 | 2 | 0.056 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.055 | |
| positive regulation of cgmp biosynthetic process | GO:0030828 | 3 | 0.055 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 61 | 0.054 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 27 | 0.053 | |
| long term memory | GO:0007616 | 2 | 0.052 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.051 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.051 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.050 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.048 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.045 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.042 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.042 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.041 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.040 | |
| cytokinesis | GO:0000910 | 96 | 0.038 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.038 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.037 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.037 | |
| response to lipid | GO:0033993 | 206 | 0.037 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.036 | |
| methylation | GO:0032259 | 106 | 0.036 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.035 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.034 | |
| protein catabolic process | GO:0030163 | 325 | 0.034 | |
| atp catabolic process | GO:0006200 | 157 | 0.034 | |
| male meiosis | GO:0007140 | 1 | 0.034 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.034 | |
| protein methylation | GO:0006479 | 74 | 0.033 | |
| female gamete generation | GO:0007292 | 2 | 0.033 | |
| protein acetylation | GO:0006473 | 116 | 0.032 | |
| single organism cellular localization | GO:1902580 | 332 | 0.032 | |
| cellular response to ionizing radiation | GO:0071479 | 32 | 0.032 | |
| organelle fission | GO:0048285 | 149 | 0.031 | |
| organelle assembly | GO:0070925 | 176 | 0.031 | |
| positive regulation of myeloid cell apoptotic process | GO:0033034 | 2 | 0.031 | |
| oocyte development | GO:0048599 | 1 | 0.031 | |
| response to other organism | GO:0051707 | 261 | 0.031 | |
| cell morphogenesis | GO:0000902 | 296 | 0.031 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.030 | |
| post embryonic development | GO:0009791 | 2 | 0.030 | Worm |
| memory | GO:0007613 | 3 | 0.030 | |
| system process | GO:0003008 | 349 | 0.030 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.030 | |
| response to fungus | GO:0009620 | 4 | 0.030 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.030 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.029 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.029 | |
| cell development | GO:0048468 | 328 | 0.029 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.028 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.028 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.028 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.028 | |
| cyclic nucleotide metabolic process | GO:0009187 | 82 | 0.027 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.027 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.027 | |
| viral life cycle | GO:0019058 | 132 | 0.027 | |
| nuclear division | GO:0000280 | 128 | 0.027 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.026 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.026 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.026 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.026 | |
| cellular response to lipid | GO:0071396 | 127 | 0.026 | |
| retinal ganglion cell axon guidance | GO:0031290 | 2 | 0.026 | |
| embryonic placenta development | GO:0001892 | 1 | 0.025 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.025 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.025 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.025 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.025 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.025 | |
| regulation of chromatin modification | GO:1903308 | 51 | 0.025 | |
| response to bacterium | GO:0009617 | 144 | 0.024 | |
| dephosphorylation | GO:0016311 | 209 | 0.024 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.024 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.024 | |
| regulation of protein processing | GO:0070613 | 150 | 0.023 | |
| protein oligomerization | GO:0051259 | 173 | 0.023 | |
| maintenance of location | GO:0051235 | 112 | 0.023 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.023 | |
| oogenesis | GO:0048477 | 2 | 0.023 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.022 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.022 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.022 | |
| secretion by cell | GO:0032940 | 226 | 0.022 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.022 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.022 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.022 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.022 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.022 | |
| protein acylation | GO:0043543 | 138 | 0.021 | |
| blastocyst formation | GO:0001825 | 3 | 0.021 | |
| regulation of viral process | GO:0050792 | 103 | 0.021 | |
| regulation of histone modification | GO:0031056 | 47 | 0.021 | |
| tube closure | GO:0060606 | 3 | 0.020 | |
| spermatid differentiation | GO:0048515 | 4 | 0.020 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.020 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.020 | |
| ameboidal type cell migration | GO:0001667 | 135 | 0.020 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.020 | |
| reproductive process | GO:0022414 | 106 | 0.020 | |
| coronary vasculature development | GO:0060976 | 2 | 0.019 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.019 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.019 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.019 | |
| vasculature development | GO:0001944 | 181 | 0.019 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.019 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.019 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.019 | |
| protein import | GO:0017038 | 130 | 0.019 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.019 | |
| regulation of meiosis | GO:0040020 | 3 | 0.019 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.018 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.018 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.018 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.018 | |
| dna repair | GO:0006281 | 198 | 0.018 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.018 | |
| regulation of binding | GO:0051098 | 111 | 0.018 | |
| ribonucleoprotein complex biogenesis | GO:0022613 | 116 | 0.018 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.018 | Worm |
| regulation of cell differentiation | GO:0045595 | 393 | 0.018 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.018 | |
| nervous system development | GO:0007399 | 293 | 0.018 | |
| histone methylation | GO:0016571 | 60 | 0.018 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.018 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.017 | |
| microtubule based process | GO:0007017 | 210 | 0.017 | |
| response to growth factor | GO:0070848 | 205 | 0.017 | |
| neural tube formation | GO:0001841 | 3 | 0.017 | |
| aorta morphogenesis | GO:0035909 | 1 | 0.017 | |
| cell adhesion | GO:0007155 | 325 | 0.017 | |
| protein deacylation | GO:0035601 | 39 | 0.017 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 24 | 0.017 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.017 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.017 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.017 | |
| response to hormone | GO:0009725 | 175 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.016 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.016 | |
| regulation of dna replication | GO:0006275 | 68 | 0.016 | |
| chromosome segregation | GO:0007059 | 114 | 0.016 | |
| protein homooligomerization | GO:0051260 | 100 | 0.016 | |
| immune response | GO:0006955 | 307 | 0.016 | |
| protein dna complex subunit organization | GO:0071824 | 80 | 0.016 | |
| primary neural tube formation | GO:0014020 | 3 | 0.016 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.016 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.016 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.016 | |
| neurogenesis | GO:0022008 | 169 | 0.016 | |
| centrosome organization | GO:0051297 | 58 | 0.016 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.016 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.016 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.016 | |
| defense response | GO:0006952 | 315 | 0.016 | |
| protein import into nucleus | GO:0006606 | 104 | 0.015 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.015 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.015 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.015 | |
| response to radiation | GO:0009314 | 151 | 0.015 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.015 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.015 | |
| termination of rna polymerase ii transcription | GO:0006369 | 1 | 0.015 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.015 | |
| neural tube closure | GO:0001843 | 3 | 0.015 | |
| histone deacetylation | GO:0016575 | 32 | 0.015 | |
| cellular response to radiation | GO:0071478 | 65 | 0.015 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.015 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.015 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.014 | |
| response to cytokine | GO:0034097 | 232 | 0.014 | |
| actin filament based process | GO:0030029 | 224 | 0.014 | |
| cell division | GO:0051301 | 168 | 0.014 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.014 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.014 | |
| nuclear import | GO:0051170 | 106 | 0.014 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.014 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.014 | |
| rna interference | GO:0016246 | 4 | 0.014 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 4 | 0.014 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.014 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.014 | |
| regulation of growth | GO:0040008 | 165 | 0.014 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.013 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.013 | |
| negative regulation of synaptic transmission | GO:0050805 | 2 | 0.013 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.013 | |
| blood vessel morphogenesis | GO:0048514 | 162 | 0.013 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.013 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.013 | |
| intracellular protein transport | GO:0006886 | 270 | 0.013 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.013 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.013 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.013 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.013 | |
| endocytosis | GO:0006897 | 159 | 0.013 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.013 | |
| multi organism cellular process | GO:0044764 | 156 | 0.013 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.013 | |
| chemical homeostasis | GO:0048878 | 306 | 0.012 | |
| spindle organization | GO:0007051 | 53 | 0.012 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.012 | |
| regulation of dephosphorylation | GO:0035303 | 96 | 0.012 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.012 | Worm |
| regulation of multi organism process | GO:0043900 | 157 | 0.012 | |
| regulation of transcription by chromatin organization | GO:0034401 | 1 | 0.012 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 109 | 0.012 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.012 | |
| epithelial cell migration | GO:0010631 | 119 | 0.012 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.012 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.012 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 90 | 0.012 | |
| hair cell differentiation | GO:0035315 | 2 | 0.012 | |
| protein localization to organelle | GO:0033365 | 280 | 0.012 | |
| protein maturation | GO:0051604 | 233 | 0.012 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.012 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.012 | |
| mrna processing | GO:0006397 | 133 | 0.012 | Rat |
| rna splicing | GO:0008380 | 131 | 0.012 | |
| cellular response to extracellular stimulus | GO:0031668 | 72 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.012 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.011 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.011 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.011 | |
| dna templated transcription termination | GO:0006353 | 3 | 0.011 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.011 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.011 | |
| ribonucleotide biosynthetic process | GO:0009260 | 81 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.011 | |
| reproduction | GO:0000003 | 63 | 0.011 | |
| response to alcohol | GO:0097305 | 64 | 0.011 | |
| chemotaxis | GO:0006935 | 157 | 0.011 | |
| erbb signaling pathway | GO:0038127 | 44 | 0.011 | |
| segmentation | GO:0035282 | 4 | 0.011 | |
| cell projection organization | GO:0030030 | 252 | 0.011 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.011 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.011 | |
| tissue migration | GO:0090130 | 119 | 0.011 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.011 | |
| membrane organization | GO:0061024 | 292 | 0.011 | |
| regulation of dna templated transcription initiation | GO:2000142 | 9 | 0.011 | |
| cell growth | GO:0016049 | 160 | 0.011 | |
| nucleosome organization | GO:0034728 | 66 | 0.011 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.011 | |
| positive regulation of axon extension | GO:0045773 | 4 | 0.010 | |
| cell cell signaling | GO:0007267 | 155 | 0.010 | |
| cardiovascular system development | GO:0072358 | 262 | 0.010 | |
| stem cell development | GO:0048864 | 69 | 0.010 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.010 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.010 | |
| developmental cell growth | GO:0048588 | 18 | 0.010 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.010 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.010 | |
| endomembrane system organization | GO:0010256 | 196 | 0.010 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.010 | |
| viral process | GO:0016032 | 146 | 0.010 | |
| central nervous system development | GO:0007417 | 123 | 0.010 | |
