Homo sapiens

18 known processes

DEFA6

defensin, alpha 6, Paneth cell-specific

(Aliases: HD-6,DEF6)

DEFA6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to biotic stimulusGO:00096072760.089
g protein coupled receptor signaling pathwayGO:00071862070.085
response to other organismGO:00517072610.084
response to external biotic stimulusGO:00432072610.076
system processGO:00030083490.072
amine metabolic processGO:0009308440.071
cellular amine metabolic processGO:0044106410.070
cellular amino acid metabolic processGO:00065201160.060
response to bacteriumGO:00096171440.059
innate immune responseGO:00450871780.057
regulation of cellular amine metabolic processGO:0033238110.057
post embryonic developmentGO:000979120.054
response to lipidGO:00339932060.052
cellular response to oxygen containing compoundGO:19017012760.052
ion transmembrane transportGO:00342203380.052
regulation of secretionGO:00510461940.051
detection of chemical stimulus involved in sensory perceptionGO:0050907330.051
anion transportGO:00068201610.051
detection of stimulusGO:0051606850.050
vesicle mediated transportGO:00161923710.049
cytoplasmic transportGO:00164823790.048
cellular lipid metabolic processGO:00442553030.047
lipid metabolic processGO:00066293810.045
cytokine productionGO:00018162470.045
cellular ketone metabolic processGO:0042180800.045
response to oxygen containing compoundGO:19017003690.045
immune responseGO:00069553070.045
regulation of cellular amino acid metabolic processGO:000652160.044
defense response to other organismGO:00985421290.043
regulation of cellular ketone metabolic processGO:0010565500.043
mapk cascadeGO:00001652880.043
cation transportGO:00068123310.042
epithelium developmentGO:00604292270.041
regulation of locomotionGO:00400123290.041
protein processingGO:00164852260.040
transmembrane transportGO:00550853990.040
actin filament based processGO:00300292240.040
secretion by cellGO:00329402260.039
rho protein signal transductionGO:0007266260.039
small gtpase mediated signal transductionGO:0007264780.038
biological adhesionGO:00226103310.037
response to organic cyclic compoundGO:00140702040.036
regulation of multi organism processGO:00439001570.036
positive regulation of cellular component organizationGO:00511303760.036
signal transduction by phosphorylationGO:00230142970.036
regulation of kinase activityGO:00435493140.035
secretionGO:00469032540.035
negative regulation of catalytic activityGO:00430863350.034
chemical homeostasisGO:00488783060.034
regulation of cell migrationGO:00303342890.034
negative regulation of multicellular organismal processGO:00512413170.034
female gamete generationGO:000729220.034
regulation of protein localizationGO:00328802960.034
defense responseGO:00069523150.033
regulation of hormone levelsGO:00108171250.033
regulation of cell motilityGO:20001452990.033
cellular response to endogenous stimulusGO:00714953360.033
negative regulation of cell deathGO:00605483450.033
cell activationGO:00017752130.033
nitrogen compound transportGO:00717051910.032
regulation of cellular component movementGO:00512703340.032
regulation of ion transportGO:00432691890.032
multicellular organismal agingGO:001025930.032
positive regulation of cell proliferationGO:00082843010.032
positive regulation of hydrolase activityGO:00513453310.031
negative regulation of cell proliferationGO:00082852280.031
determination of adult lifespanGO:000834020.031
regulation of cytokine productionGO:00018172320.031
ras protein signal transductionGO:0007265730.030
regulation of cell cycleGO:00517263930.030
protein maturationGO:00516042330.030
positive regulation of immune system processGO:00026842830.030
cation homeostasisGO:00550801890.030
positive regulation of mapk cascadeGO:00434101900.030
detection of chemical stimulusGO:0009593550.030
oogenesisGO:004847720.030
single organism cellular localizationGO:19025803320.030
muscle contractionGO:0006936730.030
positive regulation of phosphorylationGO:00423273940.029
negative regulation of transportGO:00510511760.029
metal ion homeostasisGO:00550651690.029
enzyme linked receptor protein signaling pathwayGO:00071673030.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
regulation of secretion by cellGO:19035301770.029
anatomical structure homeostasisGO:00602491000.028
epithelium migrationGO:00901321190.028
protein localization to organelleGO:00333652800.028
divalent metal ion transportGO:00708381520.028
regulation of establishment of protein localizationGO:00702012420.028
symbiosis encompassing mutualism through parasitismGO:00444031560.027
metal ion transportGO:00300012720.027
nervous system developmentGO:00073992930.027
neurological system processGO:00508771630.027
epithelial cell differentiationGO:00308551410.027
positive regulation of transportGO:00510503360.027
ribonucleotide catabolic processGO:00092614050.027
regulation of protein transportGO:00512232130.027
positive regulation of cell migrationGO:00303351720.027
carbohydrate metabolic processGO:00059752070.026
positive regulation of cellular amine metabolic processGO:003324070.026
single organism carbohydrate metabolic processGO:00447231930.026
epithelial cell migrationGO:00106311190.026
detection of chemical stimulus involved in sensory perception of smellGO:005091120.026
regulation of proteolysisGO:00301622930.026
regulation of epithelial cell proliferationGO:00506781130.025
cellular homeostasisGO:00197251960.025
positive regulation of immune responseGO:00507781590.025
negative regulation of protein metabolic processGO:00512483910.025
epithelial cell proliferationGO:00506731280.025
response to hormoneGO:00097251750.025
protein catabolic processGO:00301633250.025
positive regulation of cellular component movementGO:00512721810.025
interspecies interaction between organismsGO:00444191560.025
defense response to bacteriumGO:0042742630.025
cellular metal ion homeostasisGO:00068751460.024
intracellular protein transportGO:00068862700.024
regulation of transferase activityGO:00513383550.024
regulation of mapk cascadeGO:00434082620.024
negative regulation of cellular protein metabolic processGO:00322693530.024
cellular component morphogenesisGO:00329893140.024
regulation of leukocyte activationGO:00026941150.024
purine containing compound catabolic processGO:00725234110.024
positive regulation of programmed cell deathGO:00430682490.024
negative regulation of programmed cell deathGO:00430693210.024
purine ribonucleoside metabolic processGO:00461284370.024
cellular response to growth factor stimulusGO:00713631970.024
calcium ion transportGO:00068161470.024
negative regulation of phosphorus metabolic processGO:00105632670.024
positive regulation of cell differentiationGO:00455972110.024
cellular chemical homeostasisGO:00550821800.023
cell developmentGO:00484683280.023
positive regulation of developmental processGO:00510943140.023
response to growth factorGO:00708482050.023
regulation of protein kinase activityGO:00458592890.023
cellular cation homeostasisGO:00300031630.023
actin cytoskeleton organizationGO:00300362070.023
single organism membrane organizationGO:00448022680.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
glycosyl compound catabolic processGO:19016584130.022
protein oligomerizationGO:00512591730.022
purine ribonucleotide catabolic processGO:00091544040.022
regulation of anatomical structure morphogenesisGO:00226032860.022
cellular response to lipidGO:00713961270.022
cellular macromolecular complex assemblyGO:00346223240.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
purine nucleoside catabolic processGO:00061523980.022
purine ribonucleoside catabolic processGO:00461303980.022
regulation of cell activationGO:00508651250.021
sequestering of metal ionGO:0051238240.021
divalent inorganic cation transportGO:00725111580.021
organophosphate catabolic processGO:00464344300.021
regenerationGO:003109940.021
cellular macromolecule catabolic processGO:00442653800.021
tissue migrationGO:00901301190.021
maintenance of locationGO:00512351120.021
response to abiotic stimulusGO:00096283360.021
organic anion transportGO:00157111030.021
regulation of cell cycle processGO:00105642660.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
regulation of cellular response to stressGO:00801352440.021
negative regulation of cytokine productionGO:0001818820.021
locomotory behaviorGO:000762610.021
ameboidal type cell migrationGO:00016671350.021
cell adhesionGO:00071553250.021
ribonucleoside catabolic processGO:00424544060.020
segmentationGO:003528240.020
leukocyte activationGO:00453211640.020
nucleoside phosphate catabolic processGO:19012924120.020
regulation of intracellular transportGO:00323861950.020
cellular ion homeostasisGO:00068731680.020
regulation of nucleotide metabolic processGO:00061402690.020
memoryGO:000761330.020
nucleoside triphosphate catabolic processGO:00091433940.020
positive regulation of locomotionGO:00400171860.020
cell chemotaxisGO:00603261120.020
nucleoside triphosphate metabolic processGO:00091414220.020
positive regulation of cell motilityGO:20001471770.020
negative regulation of apoptotic processGO:00430663160.020
nucleotide catabolic processGO:00091664080.019
regulation of purine nucleotide metabolic processGO:19005422640.019
regulation of cell differentiationGO:00455953930.019
sequestering of calcium ionGO:0051208170.019
protein modification by small protein conjugationGO:00324463420.019
multicellular organismal signalingGO:0035637340.019
carbohydrate derivative biosynthetic processGO:19011372070.019
response to drugGO:0042493810.019
cell morphogenesisGO:00009022960.019
negative regulation of phosphate metabolic processGO:00459362670.019
neuromuscular junction developmentGO:000752830.019
oxidation reduction processGO:00551143960.019
regulation of endopeptidase activityGO:00525481700.019
regulation of protein catabolic processGO:00421761550.019
response to organonitrogen compoundGO:00102431560.019
blastoderm segmentationGO:000735020.019
mitotic cell cycle processGO:19030472860.018
sensory perceptionGO:00076001030.018
positive regulation of kinase activityGO:00336742040.018
response to nitrogen compoundGO:19016981840.018
response to inorganic substanceGO:00100351270.018
positive regulation of protein kinase activityGO:00458601900.018
purine nucleotide catabolic processGO:00061954050.018
mitotic cell cycleGO:00002783260.018
regulation of immune responseGO:00507762010.018
apoptotic signaling pathwayGO:00971902680.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.018
positive regulation of catabolic processGO:00098963100.018
ion homeostasisGO:00508012300.018
organic acid transportGO:0015849650.018
cardiac muscle cell contractionGO:008600340.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
hormone metabolic processGO:0042445610.018
membrane organizationGO:00610242920.018
positive regulation of organelle organizationGO:00106381950.018
morphogenesis of embryonic epitheliumGO:001633140.018
epidermis morphogenesisGO:004873030.018
positive regulation of transferase activityGO:00513472270.017
cellular protein complex assemblyGO:00436231880.017
protein targetingGO:00066051870.017
negative regulation of developmental processGO:00510932470.017
response to cytokineGO:00340972320.017
viral life cycleGO:00190581320.017
sensory perception of smellGO:000760820.017
regulation of cytoplasmic transportGO:19036491490.017
nucleocytoplasmic transportGO:00069131760.017
growthGO:00400072020.017
regulation of viral processGO:00507921030.017
regulation of response to external stimulusGO:00321012220.017
regulation of actin filament based processGO:00329701410.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
nucleoside catabolic processGO:00091644080.017
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.017
actin filament based movementGO:0030048170.017
regulation of lymphocyte activationGO:00512491030.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
regulation of cellular component biogenesisGO:00440872810.017
immune effector processGO:00022521590.017
posttranscriptional regulation of gene expressionGO:00106082130.017
cell projection organizationGO:00300302520.017
immune system developmentGO:00025201950.017
proteolysis involved in cellular protein catabolic processGO:00516032440.016
oocyte developmentGO:004859910.016
cardiac muscle contractionGO:0060048340.016
negative regulation of hydrolase activityGO:00513461820.016
hemopoiesisGO:00300971800.016
immune response regulating signaling pathwayGO:0002764970.016
regulation of growthGO:00400081650.016
positive regulation of cellular component biogenesisGO:00440891580.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
spermatid differentiationGO:004851540.016
serotonin transportGO:000683730.016
lipid biosynthetic processGO:00086101770.016
spermatid developmentGO:000728640.016
positive regulation of apoptotic processGO:00430652460.016
tissue homeostasisGO:0001894630.016
carboxylic acid transportGO:0046942630.016
wnt signaling pathwayGO:00160551560.016
multi organism cellular processGO:00447641560.016
copulationGO:000762010.016
viral processGO:00160321460.016
cellular calcium ion homeostasisGO:00068741170.015
nuclear transportGO:00511691790.015
regulation of peptidase activityGO:00525471800.015
oocyte differentiationGO:000999420.015
muscle system processGO:0003012810.015
adult locomotory behaviorGO:000834410.015
protein localization to membraneGO:00726571600.015
anterior posterior axis specificationGO:000994820.015
inseminationGO:000732010.015
cellular protein catabolic processGO:00442572610.015
establishment of protein localization to organelleGO:00725941720.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
cellular response to dna damage stimulusGO:00069743790.015
negative regulation of cellular amine metabolic processGO:003323930.015
chemotaxisGO:00069351570.015
organonitrogen compound biosynthetic processGO:19015662000.015
positive regulation of nucleotide metabolic processGO:00459812300.015
actin mediated cell contractionGO:0070252120.015
blood circulationGO:00080151130.015
positive regulation of intracellular transportGO:00323881040.015
positive regulation of cytokine productionGO:00018191670.015
regulation of protein maturationGO:19033171500.015
monocarboxylic acid metabolic processGO:00327871850.015
response to molecule of bacterial originGO:0002237820.015
amide transportGO:0042886760.015
regulation of gtp catabolic processGO:00331241800.015
cellular response to organic cyclic compoundGO:00714071270.015
dephosphorylationGO:00163112090.015
striated muscle contractionGO:0006941520.014
organophosphate biosynthetic processGO:00904071630.014
circulatory system developmentGO:00723592620.014
negative regulation of locomotionGO:00400131180.014
calcium ion homeostasisGO:00550741220.014
negative regulation of cellular component movementGO:00512711060.014
visual behaviorGO:000763220.014
i kappab kinase nf kappab signalingGO:00072491660.014
positive regulation of response to external stimulusGO:0032103880.014
regulation of purine nucleotide catabolic processGO:00331212050.014
cell growthGO:00160491600.014
endothelial cell migrationGO:0043542860.014
regulation of ras protein signal transductionGO:00465781550.014
negative regulation of intracellular signal transductionGO:19025321830.014
guanosine containing compound metabolic processGO:19010682440.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
response to fungusGO:000962040.014
protein localization to nucleusGO:00345041360.014
negative regulation of protein processingGO:00109551420.014
positive regulation of protein phosphorylationGO:00019343130.014
single organism cell adhesionGO:00986021790.014
regulation of ion homeostasisGO:2000021730.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of cytoskeleton organizationGO:00514931770.014
regulation of protein processingGO:00706131500.014
organelle assemblyGO:00709251760.014
protein ubiquitinationGO:00165673140.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
rhythmic behaviorGO:000762220.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
regulation of epithelial cell migrationGO:0010632930.014
protein importGO:00170381300.014
anion transmembrane transportGO:0098656760.014
negative regulation of cell cycleGO:00457861930.014
negative regulation of growthGO:0045926970.014
regulation of calcium ion transportGO:0051924790.014
regulation of actin cytoskeleton organizationGO:00329561160.014
chromatin organizationGO:00063253510.014
response to steroid hormoneGO:0048545800.014
negative regulation of cell migrationGO:00303361020.014
peptidyl tyrosine phosphorylationGO:00181081700.014
positive regulation of nucleoside metabolic processGO:00459791860.014
cellular response to biotic stimulusGO:0071216710.013
cation transmembrane transportGO:00986552380.013
cellular amide metabolic processGO:0043603690.013
cd8 positive alpha beta t cell activationGO:003603730.013
negative regulation of cell differentiationGO:00455961710.013
response to virusGO:00096151260.013
positive regulation of cell deathGO:00109422630.013
lymphocyte activationGO:00466491330.013
positive regulation of secretion by cellGO:19035321080.013
gtp catabolic processGO:00061842370.013
small molecule biosynthetic processGO:00442831570.013
response to axon injuryGO:004867810.013
fatty acid metabolic processGO:00066311150.013
nucleotide biosynthetic processGO:00091651090.013
establishment of protein localization to membraneGO:00901501210.013
circadian behaviorGO:004851220.013
negative regulation of protein modification processGO:00314002000.013
negative regulation of catabolic processGO:00098951040.013
negative regulation of cellular component organizationGO:00511292350.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
associative learningGO:000830610.013
serotonin uptakeGO:005161020.013
chromatin modificationGO:00165682980.013
gtp metabolic processGO:00460392390.013
sulfur compound metabolic processGO:00067901010.013
cellular response to nitrogen compoundGO:19016991440.013
phospholipid metabolic processGO:0006644990.013
negative regulation of phosphorylationGO:00423261740.013
cellular response to cytokine stimulusGO:00713451810.013
response to oxidative stressGO:00069791210.013
positive regulation of protein transportGO:00512221350.013
modification dependent macromolecule catabolic processGO:00436322120.013
regulation of cell growthGO:00015581350.013
regulation of nucleotide catabolic processGO:00308112050.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
organic hydroxy compound metabolic processGO:19016151470.013
negative regulation of protein maturationGO:19033181420.013
regulation of transmembrane transportGO:00347621390.013
tripartite regional subdivisionGO:000735120.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
guanosine containing compound catabolic processGO:19010692390.013
ubiquitin dependent protein catabolic processGO:00065112060.013
sensory perception of bitter tasteGO:0050913280.013
neurogenesisGO:00220081690.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
cellular response to organonitrogen compoundGO:00714171240.012
cell projection assemblyGO:00300311260.012
taxisGO:00423301570.012
regulation of immune effector processGO:0002697910.012
peptidyl tyrosine modificationGO:00182121700.012
endomembrane system organizationGO:00102561960.012
cell divisionGO:00513011680.012
divalent inorganic cation homeostasisGO:00725071360.012
protein secretionGO:0009306980.012
positive regulation of cell cycleGO:00457871400.012
immune response activating signal transductionGO:0002757900.012
neural tube formationGO:000184130.012
synaptic transmission glycinergicGO:006001210.012
negative regulation of multi organism processGO:0043901920.012
matingGO:000761810.012
stress activated mapk cascadeGO:0051403930.012
regulation of gtpase activityGO:00430871800.012
response to lipopolysaccharideGO:0032496700.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
single organismal cell cell adhesionGO:00163371480.012
positive regulation of acrosome reactionGO:200034440.012
regulation of erk1 and erk2 cascadeGO:0070372990.012
cardiovascular system developmentGO:00723582620.012
positive regulation of cytoskeleton organizationGO:0051495830.012
glycine importGO:003623310.012
carboxylic acid biosynthetic processGO:0046394970.012
nuclear importGO:00511701060.012
regulation of nucleoside metabolic processGO:00091182090.012
leukocyte chemotaxisGO:0030595760.012
regulation of meiotic cell cycleGO:005144540.012
negative regulation of proteolysisGO:00458611320.012
blood vessel morphogenesisGO:00485141620.012
glycerolipid metabolic processGO:00464861070.012
positive regulation of leukocyte activationGO:0002696800.012
multicellular organismal homeostasisGO:0048871670.012
detection of stimulus involved in sensory perceptionGO:0050906430.012
positive regulation of cytosolic calcium ion concentrationGO:0007204820.012
purine nucleoside monophosphate metabolic processGO:00091261860.011
regulation of metal ion transportGO:00109591200.011
positive regulation of cell activationGO:0050867810.011
nucleoside monophosphate metabolic processGO:00091231910.011
sensory perception of chemical stimulusGO:0007606380.011
anterior posterior axis specification embryoGO:000859520.011
tachykinin receptor signaling pathwayGO:000721730.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of innate immune responseGO:0045089790.011
syncytium formation by plasma membrane fusionGO:000076820.011
microtubule based processGO:00070172100.011
phototransductionGO:000760230.011
positive regulation of nucleotide catabolic processGO:00308131850.011
response to radiationGO:00093141510.011
action potentialGO:0001508340.011
positive regulation of proteolysisGO:00458621420.011
circulatory system processGO:00030131130.011
reactive oxygen species metabolic processGO:0072593750.011
postsynaptic membrane organizationGO:000194120.011
regulation of cell adhesionGO:00301551660.011
t cell activationGO:0042110990.011
regulation of innate immune responseGO:0045088970.011
negative regulation of cellular catabolic processGO:0031330830.011
cyclic nucleotide metabolic processGO:0009187820.011
regulation of cell morphogenesisGO:00226041530.011
stress activated protein kinase signaling cascadeGO:0031098940.011
steroid metabolic processGO:0008202940.011
tissue morphogenesisGO:0048729960.011
peripheral nervous system developmentGO:000742220.011
positive regulation of cellular catabolic processGO:00313312840.011
modification dependent protein catabolic processGO:00199412090.011
regulation of cell divisionGO:00513021160.011
positive regulation of erk1 and erk2 cascadeGO:0070374750.011
protein targeting to nucleusGO:00447441040.011
positive regulation of cell cycle processGO:00900681060.011
positive regulation of multi organism processGO:0043902560.011
regulation of ras gtpase activityGO:00323181280.011
actin filament organizationGO:00070151280.011
eosinophil activationGO:004330730.011
cell cycle phase transitionGO:00447701730.011
negative regulation of kinase activityGO:00336731060.011
covalent chromatin modificationGO:00165692540.011
regulation of cell developmentGO:00602841610.011
negative regulation of protein transportGO:0051224750.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of membrane potentialGO:0042391950.011
cell fate determinationGO:000170930.011
regulation of protein secretionGO:0050708860.011
tissue regenerationGO:004224630.011
glial cell migrationGO:000834740.011
retina homeostasisGO:0001895420.011
photoreceptor cell differentiationGO:004653020.011
limbic system developmentGO:002176130.011
positive regulation of cell adhesionGO:0045785840.010
negative regulation of alpha beta t cell activationGO:004663630.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
regulation of vesicle mediated transportGO:00606271300.010
organ morphogenesisGO:00098871470.010
endocytosisGO:00068971590.010
myeloid cell differentiationGO:00300991170.010
negative regulation of secretion by cellGO:1903531520.010
endothelial cell proliferationGO:0001935650.010
peptide transportGO:0015833740.010
intracellular receptor signaling pathwayGO:00305221040.010
Human

DEFA6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.044
nervous system diseaseDOID:8634310.044
disease of metabolismDOID:00146672950.032
retinal diseaseDOID:56791180.030
eye and adnexa diseaseDOID:14921500.030
eye diseaseDOID:56141490.030
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.018
inherited metabolic disorderDOID:6552420.017
retinal degenerationDOID:8466890.016
musculoskeletal system diseaseDOID:172230.015
central nervous system diseaseDOID:3311860.012
acquired metabolic diseaseDOID:0060158580.012
cardiovascular system diseaseDOID:12871060.011