Homo sapiens

36 known processes

DEFA1

defensin, alpha 1

(Aliases: DEF1,HNP-1,HP-1,MRS,DEFA2,MGC138393,DEFA1B,HP1)

DEFA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment or maintenance of cytoskeleton polarityGO:003095230.095
segmentationGO:003528240.090
cardiac right ventricle morphogenesisGO:000321530.082
anterior posterior axis specificationGO:000994820.072
morphogenesis of embryonic epitheliumGO:001633140.069
female gamete generationGO:000729220.067
embryonic epithelial tube formationGO:000183840.067
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.059
negative regulation of protein metabolic processGO:00512483910.059
right ventricular cardiac muscle tissue morphogenesisGO:000322120.056
response to biotic stimulusGO:00096072760.049
microtubule cytoskeleton organizationGO:00002261760.047
tripartite regional subdivisionGO:000735120.047
oogenesisGO:004847720.047
blastoderm segmentationGO:000735020.045
locomotory behaviorGO:000762610.045
actin filament based processGO:00300292240.044
negative regulation of smoothened signaling pathwayGO:004587930.043
defense responseGO:00069523150.041
negative regulation of hydrolase activityGO:00513461820.041
microtubule based processGO:00070172100.040
oocyte differentiationGO:000999420.036
single organism carbohydrate metabolic processGO:00447231930.036
regulation of establishment of protein localizationGO:00702012420.035
carbohydrate metabolic processGO:00059752070.035
regulation of gtp catabolic processGO:00331241800.035
oocyte developmentGO:004859910.034
negative regulation of catalytic activityGO:00430863350.034
neural tube formationGO:000184130.034
defense response to bacteriumGO:0042742630.034
innate immune responseGO:00450871780.033
defense response to other organismGO:00985421290.033
cell adhesionGO:00071553250.032
regulation of phospholipase c activating g protein coupled receptor signaling pathwayGO:190073610.032
purine nucleoside catabolic processGO:00061523980.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
cellular macromolecule catabolic processGO:00442653800.032
regulation of ion transportGO:00432691890.032
positive regulation of intracellular transportGO:00323881040.031
humoral immune responseGO:0006959490.031
negative regulation of phosphorus metabolic processGO:00105632670.031
oxidation reduction processGO:00551143960.031
cellular amine metabolic processGO:0044106410.030
purine nucleotide catabolic processGO:00061954050.030
biological adhesionGO:00226103310.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
negative regulation of jun kinase activityGO:004350840.029
hindbrain developmentGO:003090230.029
memoryGO:000761330.028
tissue morphogenesisGO:0048729960.028
cellular amino acid metabolic processGO:00065201160.027
maintenance of locationGO:00512351120.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
symbiosis encompassing mutualism through parasitismGO:00444031560.026
spermatid differentiationGO:004851540.026
regulation of protein serine threonine kinase activityGO:00719001790.026
positive regulation of synaptic transmissionGO:005080640.026
neural tube patterningGO:002153220.026
circulatory system developmentGO:00723592620.026
primary neural tube formationGO:001402030.026
purine ribonucleoside metabolic processGO:00461284370.026
cellular lipid metabolic processGO:00442553030.026
single organism cellular localizationGO:19025803320.026
regulation of cellular amine metabolic processGO:0033238110.025
negative regulation of multicellular organismal processGO:00512413170.025
cellular ketone metabolic processGO:0042180800.025
positive regulation of transportGO:00510503360.025
guanosine containing compound metabolic processGO:19010682440.025
small gtpase mediated signal transductionGO:0007264780.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.025
negative regulation of developmental processGO:00510932470.025
myeloid cell differentiationGO:00300991170.025
positive regulation of nucleotide metabolic processGO:00459812300.024
proteolysis involved in cellular protein catabolic processGO:00516032440.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
purine ribonucleotide catabolic processGO:00091544040.024
ribonucleotide catabolic processGO:00092614050.024
immune responseGO:00069553070.024
maintenance of location in cellGO:0051651620.024
intracellular protein transportGO:00068862700.024
regulation of cellular ketone metabolic processGO:0010565500.024
immune system developmentGO:00025201950.024
post embryonic developmentGO:000979120.024
negative regulation of cellular protein metabolic processGO:00322693530.023
regulation of cell differentiationGO:00455953930.023
cellular macromolecular complex assemblyGO:00346223240.023
syncytium formation by plasma membrane fusionGO:000076820.023
purine ribonucleoside catabolic processGO:00461303980.023
proteasomal protein catabolic processGO:00104981760.023
thymus developmentGO:004853830.023
negative regulation of phosphate metabolic processGO:00459362670.023
positive regulation of cellular amino acid metabolic processGO:004576430.022
protein polymerizationGO:0051258710.022
regulation of protein kinase activityGO:00458592890.022
nucleocytoplasmic transportGO:00069131760.022
regulation of intracellular transportGO:00323861950.022
positive regulation of purine nucleotide metabolic processGO:19005442270.021
regulation of kinase activityGO:00435493140.021
regulation of cellular amino acid metabolic processGO:000652160.021
gtp metabolic processGO:00460392390.021
multicellular organismal agingGO:001025930.021
tube closureGO:006060630.021
positive regulation of cellular component organizationGO:00511303760.021
cardiovascular system developmentGO:00723582620.021
cation transportGO:00068123310.021
regulation of protein localizationGO:00328802960.021
regulation of cell adhesionGO:00301551660.021
regenerationGO:003109940.021
positive regulation of cell proliferationGO:00082843010.021
heart developmentGO:0007507950.021
positive regulation of protein kinase activityGO:00458601900.020
inositol phosphate mediated signalingGO:0048016160.020
dephosphorylationGO:00163112090.020
regulation of gtpase activityGO:00430871800.020
negative regulation of phosphorylationGO:00423261740.020
regulation of transferase activityGO:00513383550.020
response to oxygen containing compoundGO:19017003690.020
organophosphate catabolic processGO:00464344300.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
negative regulation of protein modification processGO:00314002000.020
positive regulation of gtp catabolic processGO:00331261660.020
negative regulation of cellular component organizationGO:00511292350.020
neurotransmitter secretionGO:000726940.020
regulation of mapk cascadeGO:00434082620.020
cell morphogenesisGO:00009022960.020
regulation of calcium ion transportGO:0051924790.020
anion transportGO:00068201610.019
membrane organizationGO:00610242920.019
carbohydrate derivative biosynthetic processGO:19011372070.019
positive regulation of developmental processGO:00510943140.019
cerebral cortex developmentGO:0021987100.019
epithelial cell proliferationGO:00506731280.019
regulation of synaptic plasticityGO:004816730.019
ventricular septum morphogenesisGO:006041230.019
ribonucleoside catabolic processGO:00424544060.019
regulation of nucleotide catabolic processGO:00308112050.019
negative regulation of embryonic developmentGO:004599240.019
regulation of nucleotide metabolic processGO:00061402690.019
guanosine containing compound catabolic processGO:19010692390.019
regulation of intracellular protein transportGO:00331571230.018
cellular response to oxygen containing compoundGO:19017012760.018
positive regulation of cytoplasmic transportGO:1903651820.018
positive regulation of cell differentiationGO:00455972110.018
transmembrane transportGO:00550853990.018
regulation of immune responseGO:00507762010.018
regulation of cytoskeleton organizationGO:00514931770.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
spermatid developmentGO:000728640.018
positive regulation of cell deathGO:00109422630.018
organonitrogen compound biosynthetic processGO:19015662000.018
positive regulation of hydrolase activityGO:00513453310.018
cellular response to dna damage stimulusGO:00069743790.018
regulation of cellular response to stressGO:00801352440.018
reproductive processGO:00224141060.018
negative regulation of transportGO:00510511760.018
negative regulation of apoptotic processGO:00430663160.018
regulation of cellular component biogenesisGO:00440872810.018
response to other organismGO:00517072610.018
embryonic camera type eye developmentGO:003107620.017
microtubule anchoringGO:0034453240.017
neurological system processGO:00508771630.017
ras protein signal transductionGO:0007265730.017
protein localization to organelleGO:00333652800.017
maintenance of protein locationGO:0045185570.017
embryonic eye morphogenesisGO:004804820.017
regulation of protein transportGO:00512232130.017
hemopoiesisGO:00300971800.017
regulation of neural precursor cell proliferationGO:200017740.017
cellular protein complex assemblyGO:00436231880.017
osteoblast differentiationGO:0001649920.017
neuromuscular junction developmentGO:000752830.017
nucleoside triphosphate metabolic processGO:00091414220.017
purine containing compound catabolic processGO:00725234110.017
cytoplasmic transportGO:00164823790.017
compound eye developmentGO:004874910.017
synaptic transmissionGO:0007268610.017
regulation of protein maturationGO:19033171500.017
defense response to fungusGO:005083240.016
metal ion transportGO:00300012720.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
gtp catabolic processGO:00061842370.016
protein processingGO:00164852260.016
cerebral cortex cell migrationGO:002179530.016
negative regulation of protein kinase activityGO:0006469980.016
positive regulation of gtpase activityGO:00435471660.016
regulation of cell cycleGO:00517263930.016
cellular protein catabolic processGO:00442572610.016
positive regulation of nucleotide catabolic processGO:00308131850.016
cytokine productionGO:00018162470.016
epithelium developmentGO:00604292270.016
protein catabolic processGO:00301633250.016
regulation of lipid metabolic processGO:0019216960.015
regulation of protein processingGO:00706131500.015
nucleoside phosphate catabolic processGO:19012924120.015
nucleotide catabolic processGO:00091664080.015
actin cytoskeleton organizationGO:00300362070.015
organelle assemblyGO:00709251760.015
negative regulation of programmed cell deathGO:00430693210.015
outflow tract septum morphogenesisGO:000314840.015
intracellular mrna localizationGO:000829810.015
atrioventricular valve developmentGO:000317130.015
protein oligomerizationGO:00512591730.015
positive regulation of protein transportGO:00512221350.015
viral processGO:00160321460.015
myoblast fusionGO:000752010.015
positive regulation of cytokine productionGO:00018191670.015
positive regulation of cellular component biogenesisGO:00440891580.015
forebrain generation of neuronsGO:002187230.015
negative regulation of protein maturationGO:19033181420.015
protein localization to membraneGO:00726571600.015
regulation of response to dna damage stimulusGO:2001020940.015
positive regulation of kinase activityGO:00336742040.015
divalent metal ion transportGO:00708381520.015
amine metabolic processGO:0009308440.015
positive regulation of nucleoside metabolic processGO:00459791860.014
negative regulation of cell deathGO:00605483450.014
positive regulation of mapk cascadeGO:00434101900.014
protein maturationGO:00516042330.014
engulfment of apoptotic cellGO:004365220.014
interspecies interaction between organismsGO:00444191560.014
positive regulation of cell cycle processGO:00900681060.014
negative regulation of transferase activityGO:00513481240.014
regulation of multi organism processGO:00439001570.014
organ morphogenesisGO:00098871470.014
negative regulation of cytokine productionGO:0001818820.014
positive regulation of transferase activityGO:00513472270.014
nuclear transportGO:00511691790.014
divalent inorganic cation transportGO:00725111580.014
cofactor metabolic processGO:0051186870.014
regulation of cytokine productionGO:00018172320.014
cellular carbohydrate metabolic processGO:0044262840.014
regulation of purine nucleotide catabolic processGO:00331212050.014
response to external biotic stimulusGO:00432072610.014
ion transmembrane transportGO:00342203380.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
response to bacteriumGO:00096171440.014
regulation of dna metabolic processGO:00510521530.014
determination of adult lifespanGO:000834020.014
negative regulation of proteolysisGO:00458611320.014
signal transduction by phosphorylationGO:00230142970.013
maintenance of protein location in cellGO:0032507560.013
negative regulation of protein processingGO:00109551420.013
phospholipid metabolic processGO:0006644990.013
regulation of cytoplasmic transportGO:19036491490.013
chemical homeostasisGO:00488783060.013
positive regulation of cellular amine metabolic processGO:003324070.013
ion homeostasisGO:00508012300.013
regulation of cell motilityGO:20001452990.013
heart morphogenesisGO:0003007480.013
blood vessel developmentGO:00015681720.013
sleepGO:003043120.013
ossificationGO:00015031210.013
mapk cascadeGO:00001652880.013
long term memoryGO:000761620.013
wound healingGO:00420601150.013
morphogenesis of a polarized epitheliumGO:000173830.013
regulation of osteoblast differentiationGO:0045667380.013
positive regulation of apoptotic processGO:00430652460.013
immune effector processGO:00022521590.013
positive regulation of protein phosphorylationGO:00019343130.013
regulation of protein import into nucleusGO:0042306780.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of cell cycle processGO:00105642660.013
adult locomotory behaviorGO:000834410.013
ribonucleoprotein complex subunit organizationGO:0071826810.013
response to abiotic stimulusGO:00096283360.013
cellular response to lipidGO:00713961270.013
metencephalon developmentGO:002203720.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
regulation of protein localization to nucleusGO:1900180850.013
glycosyl compound catabolic processGO:19016584130.013
negative regulation of organelle organizationGO:00106391260.013
regulation of chromosome organizationGO:00330441030.012
nucleoside catabolic processGO:00091644080.012
regulation of cell morphogenesisGO:00226041530.012
epithelial tube branching involved in lung morphogenesisGO:006044140.012
negative regulation of protein phosphorylationGO:00019331400.012
cellular response to cytokine stimulusGO:00713451810.012
lipid biosynthetic processGO:00086101770.012
small molecule biosynthetic processGO:00442831570.012
regulation of erk1 and erk2 cascadeGO:0070372990.012
stem cell developmentGO:0048864690.012
response to fungusGO:000962040.012
dna repairGO:00062811980.012
mesenchyme developmentGO:0060485590.012
limbic system developmentGO:002176130.012
nuclear importGO:00511701060.012
regulation of metal ion transportGO:00109591200.012
regulation of endopeptidase activityGO:00525481700.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
response to lithium ionGO:001022620.012
anatomical structure homeostasisGO:00602491000.012
cellular response to endogenous stimulusGO:00714953360.012
response to hormoneGO:00097251750.012
negative regulation of growthGO:0045926970.012
polysaccharide metabolic processGO:0005976330.012
positive regulation of protein complex assemblyGO:0031334860.012
negative regulation of intracellular signal transductionGO:19025321830.012
multi organism cellular processGO:00447641560.012
tissue regenerationGO:004224630.012
regulation of purine nucleotide metabolic processGO:19005422640.012
mitotic nuclear divisionGO:00070671190.012
secretion by cellGO:00329402260.012
regulation of dephosphorylationGO:0035303960.012
heart valve formationGO:000318820.011
angiogenesisGO:00015251470.011
stem cell divisionGO:001714520.011
cellular component disassemblyGO:0022411920.011
regulation of proteolysisGO:00301622930.011
vesicle mediated transportGO:00161923710.011
positive regulation of immune system processGO:00026842830.011
negative regulation of non canonical wnt signaling pathwayGO:200005110.011
apoptotic signaling pathwayGO:00971902680.011
wnt signaling pathwayGO:00160551560.011
negative regulation of protein serine threonine kinase activityGO:0071901570.011
hexose metabolic processGO:0019318550.011
negative regulation of cell proliferationGO:00082852280.011
mitotic cell cycleGO:00002783260.011
mitotic cell cycle phase transitionGO:00447721620.011
chromatin organizationGO:00063253510.011
establishment of protein localization to organelleGO:00725941720.011
cardiac ventricle developmentGO:0003231230.011
autonomic nervous system developmentGO:004848310.011
regulation of nucleocytoplasmic transportGO:0046822980.011
protein targetingGO:00066051870.011
regulation of cellular component movementGO:00512703340.011
regulation of fat cell differentiationGO:0045598230.011
chromatin modificationGO:00165682980.011
cardiac chamber developmentGO:0003205300.011
methylationGO:00322591060.011
histone modificationGO:00165702510.011
nerve developmentGO:002167540.011
positive regulation of organelle organizationGO:00106381950.011
peptidyl threonine modificationGO:0018210450.011
mitochondrion organizationGO:00070051560.011
cell activationGO:00017752130.011
regulation of vesicle mediated transportGO:00606271300.011
regulation of protein catabolic processGO:00421761550.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
regulation of nucleoside metabolic processGO:00091182090.011
urogenital system developmentGO:0001655650.011
nucleoside triphosphate catabolic processGO:00091433940.011
neuroblast divisionGO:005505710.011
single organism nuclear importGO:19025931040.011
posttranscriptional regulation of gene expressionGO:00106082130.011
somatic stem cell maintenanceGO:003501940.011
associative learningGO:000830610.010
protein homooligomerizationGO:00512601000.010
negative regulation of cell differentiationGO:00455961710.010
neuroblast proliferationGO:000740540.010
mitotic cell cycle processGO:19030472860.010
regulation of anatomical structure morphogenesisGO:00226032860.010
alpha amino acid metabolic processGO:1901605720.010
positive regulation of secretionGO:00510471160.010
positive regulation of ras gtpase activityGO:00323201170.010
growthGO:00400072020.010
regulation of microtubule cytoskeleton organizationGO:0070507610.010
tube morphogenesisGO:0035239950.010
positive regulation of programmed cell deathGO:00430682490.010
rho protein signal transductionGO:0007266260.010
autophagyGO:0006914880.010
regulation of phosphatase activityGO:0010921810.010
regulation of locomotionGO:00400123290.010

DEFA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.022
neurodegenerative diseaseDOID:12891020.022
central nervous system diseaseDOID:3311860.022
disease of metabolismDOID:00146672950.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
disease of cellular proliferationDOID:145661740.017
sensory system diseaseDOID:00501552030.012
brain diseaseDOID:936730.012
inherited metabolic disorderDOID:6552420.011