Homo sapiens

119 known processes

BMI1

BMI1 polycomb ring finger oncogene

(Aliases: RNF51,FLVI2/BMI1,MGC12685,PCGF4)

BMI1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugationGO:00324463421.000
histone h2a monoubiquitinationGO:0035518111.000
Human
histone monoubiquitinationGO:0010390201.000
Human
histone h2a ubiquitinationGO:0033522171.000
Human
protein ubiquitinationGO:00165673140.998
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.994
histone ubiquitinationGO:0016574310.985
Human Mouse
regionalizationGO:0003002290.962
Mouse
response to abiotic stimulusGO:00096283360.911
negative regulation of programmed cell deathGO:00430693210.910
Mouse
response to radiationGO:00093141510.888
gene silencingGO:0016458490.886
Fly
regulation of protein modification by small protein conjugation or removalGO:19033201070.886
neuron developmentGO:00486661130.872
Fly
positive regulation of ligase activityGO:0051351190.828
negative regulation of apoptotic processGO:00430663160.813
Mouse
negative regulation of apoptotic signaling pathwayGO:2001234970.805
Mouse
cell developmentGO:00484683280.758
Fly
generation of neuronsGO:00486991520.733
Fly
chromatin modificationGO:00165682980.731
Human Mouse Fly
histone modificationGO:00165702510.719
Human Mouse
protein monoubiquitinationGO:0006513390.714
Human
response to inorganic substanceGO:00100351270.709
apoptotic signaling pathwayGO:00971902680.703
Mouse
neuron differentiationGO:00301821380.683
Fly
cellular component morphogenesisGO:00329893140.681
Fly
negative regulation of cell deathGO:00605483450.675
Mouse
proteolysis involved in cellular protein catabolic processGO:00516032440.674
response to ionizing radiationGO:0010212650.662
cellular ketone metabolic processGO:0042180800.636
segmentationGO:003528240.613
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.607
ubiquitin dependent protein catabolic processGO:00065112060.565
cellular amino acid metabolic processGO:00065201160.560
neurogenesisGO:00220081690.559
Fly
regulation of apoptotic signaling pathwayGO:20012331750.556
Mouse
spinal cord developmentGO:002151040.546
chromatin silencingGO:0006342120.542
Fly
positive regulation of programmed cell deathGO:00430682490.536
covalent chromatin modificationGO:00165692540.533
Human Mouse
regulation of cell differentiationGO:00455953930.521
Mouse
negative regulation of intracellular signal transductionGO:19025321830.498
long term memoryGO:000761620.478
chromatin organizationGO:00063253510.448
Human Mouse Fly
blastoderm segmentationGO:000735020.446
tube developmentGO:00352951250.439
Mouse
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.426
intrinsic apoptotic signaling pathwayGO:00971931270.415
cell projection organizationGO:00300302520.411
Fly
embryo developmentGO:00097901230.387
Zebrafish Mouse Fly
response to oxygen containing compoundGO:19017003690.384
tissue morphogenesisGO:0048729960.380
cell morphogenesis involved in neuron differentiationGO:0048667440.380
Fly
regulation of cell projection organizationGO:00313441070.376
modification dependent protein catabolic processGO:00199412090.374
central nervous system neuron developmentGO:002195470.366
sensory organ morphogenesisGO:0090596210.364
organ morphogenesisGO:00098871470.362
Mouse
anterior posterior axis specificationGO:000994820.354
positive regulation of transferase activityGO:00513472270.353
regulation of cellular amino acid metabolic processGO:000652160.352
cellular amine metabolic processGO:0044106410.331
neuromuscular junction developmentGO:000752830.324
eye morphogenesisGO:0048592160.312
fibroblast proliferationGO:0048144330.312
gastrulation with mouth forming secondGO:000170210.301
neuron projection developmentGO:00311751060.299
Fly
chemotaxisGO:00069351570.298
Fly
ribonucleoprotein complex biogenesisGO:00226131160.298
rna splicingGO:00083801310.295
memoryGO:000761330.292
mrna splicing via spliceosomeGO:0000398890.287
post embryonic developmentGO:000979120.286
regulation of behaviorGO:0050795820.284
regulation of neuron differentiationGO:0045664700.275
posttranscriptional regulation of gene expressionGO:00106082130.265
regulation of multi organism processGO:00439001570.254
response to gamma radiationGO:0010332140.247
regulation of axon guidanceGO:190266730.247
regulation of cellular ketone metabolic processGO:0010565500.243
regulation of cellular amine metabolic processGO:0033238110.242
hematopoietic or lymphoid organ developmentGO:00485341860.238
mrna processingGO:00063971330.236
regulation of gene expression epigeneticGO:0040029730.229
Mouse Fly
positive regulation of cell deathGO:00109422630.228
axonogenesisGO:0007409310.223
Fly
mrna metabolic processGO:00160711750.213
nervous system developmentGO:00073992930.209
Zebrafish Mouse Fly
nitrogen compound transportGO:00717051910.205
embryonic organ morphogenesisGO:0048562240.204
Mouse
neurotransmitter secretionGO:000726940.198
regulation of kinase activityGO:00435493140.197
neuron remodelingGO:001632220.196
embryonic morphogenesisGO:0048598850.181
Mouse
modification dependent macromolecule catabolic processGO:00436322120.178
negative regulation of protein metabolic processGO:00512483910.166
rna processingGO:00063962550.166
cellular homeostasisGO:00197251960.165
axon developmentGO:0061564340.162
Fly
neuron projection morphogenesisGO:0048812500.159
Fly
cellular macromolecule catabolic processGO:00442653800.158
chemical homeostasisGO:00488783060.158
dendrite developmentGO:0016358240.153
regulation of protein ubiquitinationGO:0031396950.153
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.152
regulation of cellular component biogenesisGO:00440872810.146
cellular protein catabolic processGO:00442572610.144
regulation of transferase activityGO:00513383550.142
developmental maturationGO:0021700280.141
positive regulation of kinase activityGO:00336742040.140
cell part morphogenesisGO:00329901370.139
Fly
regulation of neurogenesisGO:0050767820.139
female gamete generationGO:000729220.139
chromatin assembly or disassemblyGO:0006333780.138
amine metabolic processGO:0009308440.136
cellular response to oxygen containing compoundGO:19017012760.133
regulation of neuron projection developmentGO:0010975570.129
negative regulation of gene expression epigeneticGO:0045814190.128
Fly
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.127
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.127
oocyte differentiationGO:000999420.125
regulation of cellular component sizeGO:0032535820.124
connective tissue developmentGO:0061448390.124
camera type eye morphogenesisGO:0048593120.123
cell projection morphogenesisGO:00488581290.119
Fly
regulation of developmental growthGO:0048638300.118
cartilage developmentGO:0051216310.115
positive regulation of developmental processGO:00510943140.112
Mouse
carbohydrate metabolic processGO:00059752070.107
regulation of protein kinase activityGO:00458592890.105
taxisGO:00423301570.104
Fly
digestive tract morphogenesisGO:0048546560.102
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.100
cation transportGO:00068123310.095
regulation of growthGO:00400081650.095
vesicle mediated transportGO:00161923710.094
positive regulation of cell proliferationGO:00082843010.093
positive regulation of protein phosphorylationGO:00019343130.093
pattern specification processGO:0007389430.091
Mouse
mitotic cell cycleGO:00002783260.090
Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.087
sensory organ developmentGO:0007423520.085
negative regulation of cellular protein metabolic processGO:00322693530.081
oocyte developmentGO:004859910.076
regulation of cell morphogenesisGO:00226041530.075
circadian sleep wake cycleGO:004274520.075
response to oxidative stressGO:00069791210.074
anterior posterior pattern specificationGO:000995290.073
Mouse
purine ribonucleotide biosynthetic processGO:0009152790.072
single organism carbohydrate metabolic processGO:00447231930.071
sleepGO:003043120.070
eye developmentGO:0001654420.069
regulation of fibroblast proliferationGO:0048145320.068
regulation of system processGO:00440571010.068
positive regulation of protein kinase activityGO:00458601900.067
positive regulation of cellular amine metabolic processGO:003324070.067
nucleic acid transportGO:0050657390.067
response to organic cyclic compoundGO:00140702040.066
rostrocaudal neural tube patterningGO:002190310.066
Mouse
chromatin assemblyGO:0031497610.066
neural tube patterningGO:002153220.065
Mouse
regulation of nervous system developmentGO:0051960880.065
gastrulationGO:0007369510.064
embryonic cranial skeleton morphogenesisGO:004870160.064
cellular response to acid chemicalGO:0071229440.063
peptidyl tyrosine modificationGO:00182121700.060
positive regulation of cell differentiationGO:00455972110.058
Mouse
embryonic skeletal system morphogenesisGO:004870490.058
Mouse
single organism cellular localizationGO:19025803320.058
growthGO:00400072020.057
negative regulation of developmental processGO:00510932470.056
negative regulation of protein modification processGO:00314002000.055
cell morphogenesisGO:00009022960.055
Fly
wnt signaling pathwayGO:00160551560.055
ion homeostasisGO:00508012300.054
secretionGO:00469032540.053
regulation of intracellular transportGO:00323861950.053
neurological system processGO:00508771630.053
oogenesisGO:004847720.053
behaviorGO:00076101120.052
regulation of synaptic transmissionGO:0050804110.052
negative regulation of growthGO:0045926970.052
neuron projection guidanceGO:0097485120.050
Fly
response to alcoholGO:0097305640.050
negative regulation of synaptic transmissionGO:005080520.050
short term memoryGO:000761410.049
internal peptidyl lysine acetylationGO:0018393970.048
Mouse
regulation of rna splicingGO:0043484620.048
response to reactive oxygen speciesGO:0000302610.048
matingGO:000761810.047
gland developmentGO:0048732480.047
rna localizationGO:0006403410.046
cellular response to oxidative stressGO:0034599850.046
negative regulation of multicellular organismal processGO:00512413170.045
regulation of histone h3 k27 methylationGO:006108540.044
cellular lipid metabolic processGO:00442553030.044
digestive tract developmentGO:0048565750.044
regulation of secretion by cellGO:19035301770.044
nucleotide biosynthetic processGO:00091651090.043
symbiosis encompassing mutualism through parasitismGO:00444031560.043
negative regulation of phosphorylationGO:00423261740.043
negative regulation of phosphorus metabolic processGO:00105632670.043
skeletal system morphogenesisGO:0048705240.042
Mouse
regulation of axon extension involved in axon guidanceGO:004884120.042
regulation of cell morphogenesis involved in differentiationGO:0010769830.042
central nervous system developmentGO:00074171230.042
Zebrafish Mouse
alternative mrna splicing via spliceosomeGO:0000380270.041
response to decreased oxygen levelsGO:0036293960.041
cell morphogenesis involved in differentiationGO:00009041440.041
Fly
cellular response to decreased oxygen levelsGO:0036294510.040
axon regenerationGO:003110310.039
regulation of neural precursor cell proliferationGO:200017740.039
spermatid developmentGO:000728640.039
proteasomal protein catabolic processGO:00104981760.039
enzyme linked receptor protein signaling pathwayGO:00071673030.039
multicellular organismal agingGO:001025930.038
immune responseGO:00069553070.038
Mouse
long term synaptic potentiationGO:006029110.037
metal ion transportGO:00300012720.037
chromatin remodelingGO:0006338550.037
Fly
positive regulation of cell developmentGO:0010720920.037
response to lipidGO:00339932060.037
positive regulation of apoptotic signaling pathwayGO:2001235700.036
mapk cascadeGO:00001652880.036
behavioral response to ethanolGO:004814920.036
circadian sleep wake cycle sleepGO:005080220.036
negative regulation of protein kinase b signalingGO:0051898170.034
carboxylic acid biosynthetic processGO:0046394970.033
synapse organizationGO:0050808140.033
positive regulation of phosphorylationGO:00423273940.033
regulation of cell developmentGO:00602841610.033
reproductive processGO:00224141060.033
response to retinoic acidGO:0032526330.032
response to hormoneGO:00097251750.032
negative regulation of phosphate metabolic processGO:00459362670.032
cell type specific apoptotic processGO:00972851250.032
anatomical structure formation involved in morphogenesisGO:00486462840.031
establishment of rna localizationGO:0051236390.031
embryonic organ developmentGO:0048568360.031
Zebrafish Mouse
purine nucleotide biosynthetic processGO:0006164840.030
positive regulation of myeloid cell apoptotic processGO:003303420.030
positive regulation of apoptotic processGO:00430652460.030
neuron deathGO:0070997650.030
generation of precursor metabolites and energyGO:0006091680.030
cellular response to growth factor stimulusGO:00713631970.030
positive regulation of neural precursor cell proliferationGO:200017920.029
dephosphorylationGO:00163112090.029
cell cell signalingGO:00072671550.029
dendrite morphogenesisGO:0048813140.029
negative regulation of cellular amine metabolic processGO:003323930.028
signal releaseGO:0023061700.028
regulation of mrna splicing via spliceosomeGO:0048024320.028
response to woundingGO:00096111680.028
determination of adult lifespanGO:000834020.028
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.028
regulation of mrna processingGO:0050684480.028
protein complex disassemblyGO:0043241520.027
nucleocytoplasmic transportGO:00069131760.027
peptidyl lysine modificationGO:00182051440.027
Mouse
appendage developmentGO:0048736230.027
signal transduction by p53 class mediatorGO:0072331720.026
mrna transportGO:0051028300.026
negative regulation of neurological system processGO:003164520.026
regulation of ubiquitin protein transferase activityGO:0051438280.026
organonitrogen compound biosynthetic processGO:19015662000.026
protein localization to organelleGO:00333652800.026
ossificationGO:00015031210.026
neuroblast proliferationGO:000740540.026
ribonucleoprotein complex assemblyGO:0022618780.026
tissue migrationGO:00901301190.026
system processGO:00030083490.026
somitogenesisGO:000175620.025
peptidyl tyrosine phosphorylationGO:00181081700.025
macromolecule methylationGO:0043414970.025
Mouse
negative regulation of phagocytosisGO:005076540.025
intracellular protein transportGO:00068862700.025
regulation of axon regenerationGO:004867910.024
mesenchyme developmentGO:0060485590.024
hemopoiesisGO:00300971800.024
regulation of cellular response to stressGO:00801352440.024
synaptic transmissionGO:0007268610.024
dendritic spine morphogenesisGO:006099730.024
ribose phosphate biosynthetic processGO:0046390820.024
heart developmentGO:0007507950.024
response to extracellular stimulusGO:0009991850.024
stress activated protein kinase signaling cascadeGO:0031098940.023
negative regulation of translationGO:0017148370.023
chondrocyte differentiationGO:0002062170.023
regulation of protein kinase b signalingGO:0051896610.023
regulation of cgmp biosynthetic processGO:003082640.023
negative regulation of hydrolase activityGO:00513461820.023
viral life cycleGO:00190581320.022
convergent extensionGO:006002610.022
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.022
positive regulation of neurogenesisGO:0050769490.022
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.022
protein kinase b signalingGO:0043491690.021
circadian sleep wake cycle processGO:002241020.021
response to organonitrogen compoundGO:00102431560.021
ribonucleotide biosynthetic processGO:0009260810.021
sex differentiationGO:0007548450.021
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.021
cgmp metabolic processGO:0046068190.021
response to acid chemicalGO:0001101660.021
negative regulation of kinase activityGO:00336731060.021
secretion by cellGO:00329402260.021
digestive system developmentGO:0055123750.020
membrane organizationGO:00610242920.020
negative regulation of nervous system developmentGO:0051961280.020
cell maturationGO:0048469110.020
stress activated mapk cascadeGO:0051403930.020
negative regulation of cell proliferationGO:00082852280.020
camera type eye developmentGO:0043010250.020
negative regulation of cellular component organizationGO:00511292350.020
retina development in camera type eyeGO:0060041150.020
regulation of chondrocyte differentiationGO:003233090.020
regulation of wnt signaling pathwayGO:00301111230.020
regulation of ion transportGO:00432691890.020
positive regulation of synaptic transmissionGO:005080640.020
response to metal ionGO:0010038840.020
transforming growth factor beta receptor signaling pathwayGO:0007179760.020
cellular response to abiotic stimulusGO:00712141170.020
sister chromatid cohesionGO:0007062240.019
cytoplasmic transportGO:00164823790.019
erbb signaling pathwayGO:0038127440.019
cellular response to nitrogen compoundGO:19016991440.019
negative regulation of nf kappab transcription factor activityGO:0032088510.019
interspecies interaction between organismsGO:00444191560.019
positive regulation of nervous system developmentGO:0051962540.019
protein homooligomerizationGO:00512601000.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.018
regulation of dendrite morphogenesisGO:0048814110.018
dna conformation changeGO:00711031130.018
rhythmic behaviorGO:000762220.018
rhythmic processGO:0048511310.018
organophosphate biosynthetic processGO:00904071630.018
negative regulation of dendritic spine developmentGO:006100010.018
regulation of dendrite developmentGO:0050773180.018
peptide transportGO:0015833740.018
regulation of protein stabilityGO:0031647870.018
regulation of homeostatic processGO:00328441210.018
regulation of anatomical structure sizeGO:00900661010.017
multicellular organism reproductionGO:0032504420.017
receptor mediated endocytosisGO:0006898840.017
detection of mechanical stimulus involved in sensory perceptionGO:005097410.017
regulation of dephosphorylationGO:0035303960.017
axoneme assemblyGO:003508230.017
inner ear morphogenesisGO:004247240.017
organelle assemblyGO:00709251760.017
transmembrane transportGO:00550853990.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
regulation of synapse assemblyGO:005196350.017
positive regulation of cellular component organizationGO:00511303760.017
axon extensionGO:0048675130.017
regulation of mapk cascadeGO:00434082620.017
ribonucleoprotein complex localizationGO:007116640.017
epithelium migrationGO:00901321190.017
trophectodermal cell differentiationGO:000182930.017
regulation of stress activated protein kinase signaling cascadeGO:0070302850.017
central nervous system myelinationGO:002201010.017
i kappab kinase nf kappab signalingGO:00072491660.016
multi organism cellular processGO:00447641560.016
regulation of anatomical structure morphogenesisGO:00226032860.016
nuclear transportGO:00511691790.016
cellular macromolecular complex assemblyGO:00346223240.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
nucleoside phosphate biosynthetic processGO:19012931090.016
cell cycle checkpointGO:00000751170.016
protein catabolic processGO:00301633250.016
spermatid differentiationGO:004851540.016
axis specificationGO:0009798120.016
jnk cascadeGO:0007254800.015
protein localization to nucleusGO:00345041360.015
negative regulation of transferase activityGO:00513481240.015
negative regulation of catalytic activityGO:00430863350.015
cellular ion homeostasisGO:00068731680.015
regulation of phosphatase activityGO:0010921810.015
cellular response to peptideGO:1901653590.015
immune system developmentGO:00025201950.015
single organism behaviorGO:0044708280.015
circadian behaviorGO:004851220.015
cellular response to endogenous stimulusGO:00714953360.014
cilium morphogenesisGO:0060271750.014
nucleobase containing compound transportGO:0015931510.014
renal sodium ion transportGO:000309620.014
autophagyGO:0006914880.014
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.014
regulation of stress activated mapk cascadeGO:0032872840.014
regulation of translationGO:0006417890.014
head developmentGO:00603221080.014
Zebrafish Mouse
establishment of tissue polarityGO:000716430.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
monovalent inorganic cation transportGO:00156721280.014
cognitionGO:0050890430.014
response to hypoxiaGO:0001666960.014
cell projection assemblyGO:00300311260.014
protein dephosphorylationGO:0006470810.013
regulation of cyclic nucleotide biosynthetic processGO:0030802490.013
carbohydrate derivative biosynthetic processGO:19011372070.013
cellular chemical homeostasisGO:00550821800.013
regulation of establishment of protein localizationGO:00702012420.013
regulation of axonogenesisGO:0050770160.013
blastocyst formationGO:000182530.013
intracellular mrna localizationGO:000829810.013
regulation of signal transduction by p53 class mediatorGO:1901796260.013
regulation of mrna metabolic processGO:1903311530.013
cellular response to organonitrogen compoundGO:00714171240.013
ameboidal type cell migrationGO:00016671350.013
negative regulation of protein phosphorylationGO:00019331400.013
multicellular organismal homeostasisGO:0048871670.012
negative regulation of cell morphogenesis involved in differentiationGO:0010771240.012
purine containing compound biosynthetic processGO:0072522880.012
negative regulation of developmental growthGO:0048640100.012
histone methylationGO:0016571600.012
viral transcriptionGO:0019083350.012
protein import into nucleusGO:00066061040.012
endothelial cell migrationGO:0043542860.012
positive regulation of nucleotide metabolic processGO:00459812300.012
regulation of viral processGO:00507921030.012
regulation of cgmp metabolic processGO:003082390.012
response to nitrogen compoundGO:19016981840.012
negative regulation of immune effector processGO:0002698380.012
primary neural tube formationGO:001402030.011
regulation of dna metabolic processGO:00510521530.011
t cell activationGO:0042110990.011
Mouse
cellular response to uvGO:0034644320.011
ncrna processingGO:0034470830.011
cellular cation homeostasisGO:00300031630.011
response to peptideGO:1901652650.011
bmp signaling pathwayGO:0030509490.011
cation homeostasisGO:00550801890.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
energy derivation by oxidation of organic compoundsGO:0015980430.011
presynaptic membrane organizationGO:009709030.011
response to oxygen levelsGO:00704821000.011
dendritic spine organizationGO:009706140.011
cyclic nucleotide metabolic processGO:0009187820.011
locomotory behaviorGO:000762610.011
phosphatidylinositol dephosphorylationGO:004685670.011
neuron apoptotic processGO:0051402390.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
protein deubiquitinationGO:0016579790.010
chordate embryonic developmentGO:0043009340.010
Mouse
ear developmentGO:0043583140.010
sensory perceptionGO:00076001030.010
regulation of chromatin modificationGO:1903308510.010
positive regulation of cgmp metabolic processGO:003082550.010
fatty acid metabolic processGO:00066311150.010
organelle localizationGO:0051640840.010
negative regulation of neuron projection developmentGO:0010977150.010
regulation of neuroblast proliferationGO:190269230.010
cellular response to reactive oxygen speciesGO:0034614500.010
regulation of cyclic nucleotide metabolic processGO:0030799630.010
gene silencing by rnaGO:0031047260.010

BMI1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.023
disease of cellular proliferationDOID:145661740.023
endocrine gland cancerDOID:170260.020
organ system cancerDOID:00506861640.020