Homo sapiens

270 known processes

MIF

macrophage migration inhibitory factor (glycosylation-inhibiting factor)

(Aliases: GIF,GLIF,MMIF)

MIF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.953
monocarboxylic acid metabolic processGO:00327871850.836
nucleotide biosynthetic processGO:00091651090.795
cellular response to dna damage stimulusGO:00069743790.571
negative regulation of mitotic cell cycleGO:00459301020.487
negative regulation of developmental processGO:00510932470.443
positive regulation of camp biosynthetic processGO:0030819350.410
response to oxygen containing compoundGO:19017003690.384
post embryonic developmentGO:000979120.363
negative regulation of cell deathGO:00605483450.362
purine ribonucleotide biosynthetic processGO:0009152790.320
dna integrity checkpointGO:0031570710.316
cellular amine metabolic processGO:0044106410.302
cellular response to oxygen containing compoundGO:19017012760.297
response to organic cyclic compoundGO:00140702040.296
regulation of transferase activityGO:00513383550.276
cofactor metabolic processGO:0051186870.270
regulation of cell differentiationGO:00455953930.269
nucleoside phosphate biosynthetic processGO:19012931090.253
regulation of cellular amine metabolic processGO:0033238110.246
positive regulation of cellular amine metabolic processGO:003324070.246
defense responseGO:00069523150.243
cellular ketone metabolic processGO:0042180800.240
negative regulation of apoptotic processGO:00430663160.240
carbohydrate derivative biosynthetic processGO:19011372070.226
regulation of camp metabolic processGO:0030814520.221
cellular homeostasisGO:00197251960.220
immune system developmentGO:00025201950.216
negative regulation of catalytic activityGO:00430863350.215
carbohydrate metabolic processGO:00059752070.208
vitamin metabolic processGO:0006766260.204
regulation of cyclic nucleotide biosynthetic processGO:0030802490.203
negative regulation of programmed cell deathGO:00430693210.200
ribonucleotide biosynthetic processGO:0009260810.194
purine nucleotide biosynthetic processGO:0006164840.192
chemical homeostasisGO:00488783060.192
regulation of cell cycle processGO:00105642660.188
response to lipidGO:00339932060.187
organophosphate biosynthetic processGO:00904071630.184
single organism carbohydrate metabolic processGO:00447231930.180
multicellular organismal agingGO:001025930.173
negative regulation of phosphorylationGO:00423261740.172
anatomical structure formation involved in morphogenesisGO:00486462840.169
negative regulation of cellular protein metabolic processGO:00322693530.166
ribonucleoside monophosphate metabolic processGO:00091611870.163
determination of adult lifespanGO:000834020.161
apoptotic signaling pathwayGO:00971902680.160
negative regulation of cell differentiationGO:00455961710.157
negative regulation of multicellular organismal processGO:00512413170.150
response to monosaccharideGO:0034284200.149
cellular macromolecular complex assemblyGO:00346223240.139
carbohydrate catabolic processGO:0016052360.139
cellular macromolecule catabolic processGO:00442653800.138
positive regulation of cell proliferationGO:00082843010.137
camp metabolic processGO:0046058610.134
purine containing compound biosynthetic processGO:0072522880.133
single organism carbohydrate catabolic processGO:0044724330.132
mitotic cell cycleGO:00002783260.131
cellular amino acid metabolic processGO:00065201160.129
response to acid chemicalGO:0001101660.126
glucose homeostasisGO:0042593310.125
positive regulation of phosphorylationGO:00423273940.123
negative regulation of cell cycle phase transitionGO:1901988890.122
negative regulation of protein metabolic processGO:00512483910.122
hemopoiesisGO:00300971800.121
cellular response to cytokine stimulusGO:00713451810.116
mitotic cell cycle phase transitionGO:00447721620.114
growthGO:00400072020.113
regulation of camp biosynthetic processGO:0030817450.113
glycolytic processGO:0006096170.112
purine ribonucleoside biosynthetic processGO:0046129230.111
negative regulation of cell proliferationGO:00082852280.110
positive regulation of cellular amino acid metabolic processGO:004576430.108
cell cycle checkpointGO:00000751170.107
superoxide metabolic processGO:0006801200.103
regulation of nucleotide metabolic processGO:00061402690.102
regulation of kinase activityGO:00435493140.101
cell developmentGO:00484683280.100
leukocyte differentiationGO:0002521980.099
atp biosynthetic processGO:0006754110.098
cyclic purine nucleotide metabolic processGO:0052652600.098
posttranscriptional regulation of gene expressionGO:00106082130.097
regulation of mitotic cell cycleGO:00073461890.096
adult locomotory behaviorGO:000834410.094
response to other organismGO:00517072610.093
mitotic dna damage checkpointGO:0044773280.093
regulation of myeloid cell differentiationGO:0045637810.092
regulation of cytokine productionGO:00018172320.092
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.090
cellular response to external stimulusGO:00714961110.086
neuron projection developmentGO:00311751060.086
nervous system developmentGO:00073992930.085
regulation of cyclic nucleotide metabolic processGO:0030799630.085
cellular response to oxidative stressGO:0034599850.084
hemostasisGO:0007599760.083
immune effector processGO:00022521590.082
regulation of cellular response to stressGO:00801352440.080
reactive oxygen species metabolic processGO:0072593750.078
cellular component morphogenesisGO:00329893140.077
camp biosynthetic processGO:0006171470.077
cellular response to lipidGO:00713961270.075
regulation of protein serine threonine kinase activityGO:00719001790.075
hematopoietic or lymphoid organ developmentGO:00485341860.074
nucleoside diphosphate metabolic processGO:0009132160.074
regulation of cellular ketone metabolic processGO:0010565500.074
methylationGO:00322591060.074
regulation of leukocyte differentiationGO:1902105610.073
female gamete generationGO:000729220.072
regulation of cell cycleGO:00517263930.070
mitotic cell cycle processGO:19030472860.070
ribose phosphate biosynthetic processGO:0046390820.070
cellular chemical homeostasisGO:00550821800.069
regulation of mapk cascadeGO:00434082620.069
blastocyst developmentGO:000182430.067
peptidyl glutamic acid modificationGO:001820040.067
negative regulation of phosphorus metabolic processGO:00105632670.067
response to oxidative stressGO:00069791210.067
cell cycle phase transitionGO:00447701730.066
negative regulation of cell cycle processGO:00109481210.066
cell activationGO:00017752130.065
regulation of growthGO:00400081650.065
muscle structure developmentGO:0061061980.063
negative regulation of cellular component organizationGO:00511292350.062
ribonucleoprotein complex biogenesisGO:00226131160.061
myeloid cell differentiationGO:00300991170.060
generation of precursor metabolites and energyGO:0006091680.060
microtubule based processGO:00070172100.059
cation transportGO:00068123310.059
defense response to other organismGO:00985421290.058
cell adhesionGO:00071553250.058
regulation of reactive oxygen species metabolic processGO:2000377410.057
pyrimidine ribonucleoside metabolic processGO:0046131110.056
response to external biotic stimulusGO:00432072610.056
mapk cascadeGO:00001652880.055
segmentationGO:003528240.055
myoblast fusionGO:000752010.054
negative regulation of myeloid cell differentiationGO:0045638420.054
regulation of membrane potentialGO:0042391950.054
regulation of mitotic cell cycle phase transitionGO:19019901180.054
positive regulation of bindingGO:0051099450.053
cell projection organizationGO:00300302520.053
nucleoside diphosphate phosphorylationGO:0006165120.052
pyruvate metabolic processGO:0006090260.052
epithelial cell differentiationGO:00308551410.052
taxisGO:00423301570.051
regulation of epithelial cell proliferationGO:00506781130.051
regulation of body fluid levelsGO:0050878990.050
response to virusGO:00096151260.050
mrna metabolic processGO:00160711750.050
negative regulation of phosphate metabolic processGO:00459362670.049
negative regulation of mitotic cell cycle phase transitionGO:1901991850.049
organonitrogen compound biosynthetic processGO:19015662000.049
pattern specification processGO:0007389430.048
positive regulation of transportGO:00510503360.048
regulation of cellular component movementGO:00512703340.048
positive regulation of purine nucleotide biosynthetic processGO:1900373380.048
neuron differentiationGO:00301821380.048
cyclic nucleotide biosynthetic processGO:0009190610.048
regulation of locomotionGO:00400123290.047
positive regulation of reactive oxygen species metabolic processGO:2000379240.046
organelle assemblyGO:00709251760.046
response to carbohydrateGO:0009743210.046
dna damage checkpointGO:0000077680.046
lipid biosynthetic processGO:00086101770.045
myosin filament organizationGO:003103320.045
metal ion transportGO:00300012720.045
stress activated mapk cascadeGO:0051403930.045
neurogenesisGO:00220081690.044
defense response to virusGO:0051607710.044
cellular metal ion homeostasisGO:00068751460.043
chemotaxisGO:00069351570.043
mitotic cell cycle checkpointGO:0007093680.043
myeloid leukocyte differentiationGO:0002573600.042
cellular protein catabolic processGO:00442572610.042
cytokine productionGO:00018162470.042
positive regulation of cellular component organizationGO:00511303760.042
regulation of purine nucleotide biosynthetic processGO:1900371500.042
negative regulation of apoptotic signaling pathwayGO:2001234970.041
amine metabolic processGO:0009308440.041
carbohydrate homeostasisGO:0033500310.041
gtp metabolic processGO:00460392390.041
regulation of multi organism processGO:00439001570.040
regulation of cell motilityGO:20001452990.040
cell type specific apoptotic processGO:00972851250.040
regulation of apoptotic signaling pathwayGO:20012331750.040
negative regulation of protein maturationGO:19033181420.039
cellular response to endogenous stimulusGO:00714953360.039
regulation of stress activated mapk cascadeGO:0032872840.039
purine ribonucleoside metabolic processGO:00461284370.039
regulation of cell growthGO:00015581350.038
regulation of meiotic cell cycleGO:005144540.038
stress activated protein kinase signaling cascadeGO:0031098940.037
regulation of response to woundingGO:19030341010.037
cell morphogenesisGO:00009022960.037
response to biotic stimulusGO:00096072760.037
purine ribonucleoside monophosphate metabolic processGO:00091671860.037
metal ion homeostasisGO:00550651690.037
negative regulation of transferase activityGO:00513481240.036
epithelium developmentGO:00604292270.036
mrna catabolic processGO:0006402560.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
regulation of cell projection organizationGO:00313441070.036
atp synthesis coupled electron transportGO:004277340.036
regulation of nucleotide biosynthetic processGO:0030808500.036
regulation of myeloid leukocyte differentiationGO:0002761390.035
negative regulation of protein modification processGO:00314002000.035
receptor mediated endocytosisGO:0006898840.035
signal transduction by phosphorylationGO:00230142970.035
response to hormoneGO:00097251750.035
g2 dna damage checkpointGO:0031572260.034
protein localization to organelleGO:00333652800.034
positive regulation of developmental processGO:00510943140.034
positive regulation of camp metabolic processGO:0030816410.033
positive regulation of cytokine productionGO:00018191670.033
nuclear transportGO:00511691790.033
hydrogen peroxide catabolic processGO:0042744130.033
innate immune responseGO:00450871780.033
response to nitrogen compoundGO:19016981840.032
nucleoside biosynthetic processGO:0009163260.032
cellular modified amino acid metabolic processGO:0006575640.031
cellular response to hormone stimulusGO:00328701250.031
protein maturationGO:00516042330.030
purine ribonucleoside triphosphate biosynthetic processGO:0009206110.030
striated muscle myosin thick filament assemblyGO:007168820.030
nuclear transcribed mrna catabolic processGO:0000956480.029
regulation of cell migrationGO:00303342890.029
leukocyte proliferationGO:0070661740.029
cell growthGO:00160491600.029
protein processingGO:00164852260.028
single organism cell adhesionGO:00986021790.028
guanosine containing compound metabolic processGO:19010682440.027
vesicle mediated transportGO:00161923710.027
response to organonitrogen compoundGO:00102431560.026
muscle cell cellular homeostasisGO:004671630.026
regulation of mitochondrial membrane potentialGO:0051881230.026
extrinsic apoptotic signaling pathwayGO:00971911190.026
regulation of protein localizationGO:00328802960.026
positive regulation of purine nucleotide metabolic processGO:19005442270.025
regulation of cellular amino acid metabolic processGO:000652160.025
negative regulation of immune system processGO:00026831360.025
mitotic dna integrity checkpointGO:0044774300.025
negative regulation of protein processingGO:00109551420.025
protein autophosphorylationGO:00467771230.025
regenerationGO:003109940.025
nucleocytoplasmic transportGO:00069131760.025
regulation of map kinase activityGO:00434051080.025
ribonucleoside biosynthetic processGO:0042455250.024
positive regulation of apoptotic processGO:00430652460.024
cell morphogenesis involved in differentiationGO:00009041440.024
system processGO:00030083490.024
negative regulation of proteolysisGO:00458611320.024
platelet activationGO:0030168440.024
regulation of protein maturationGO:19033171500.024
blood coagulationGO:0007596760.024
response to glucoseGO:0009749190.023
response to bacteriumGO:00096171440.023
regulation of bindingGO:00510981110.023
regulation of protein processingGO:00706131500.023
protein modification by small protein conjugationGO:00324463420.023
myeloid cell homeostasisGO:0002262340.023
macromolecule methylationGO:0043414970.023
positive regulation of transferase activityGO:00513472270.023
negative regulation of leukocyte differentiationGO:1902106240.023
regulation of superoxide metabolic processGO:009032260.023
regulation of purine nucleotide metabolic processGO:19005422640.022
response to reactive oxygen speciesGO:0000302610.022
peptidyl serine phosphorylationGO:00181051010.022
actin filament based processGO:00300292240.022
response to woundingGO:00096111680.022
epithelial cell proliferationGO:00506731280.022
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.022
mitotic g2 dna damage checkpointGO:000709570.022
calcium ion transportGO:00068161470.022
alpha amino acid metabolic processGO:1901605720.022
response to toxic substanceGO:0009636370.022
negative regulation of hydrolase activityGO:00513461820.021
positive regulation of cell developmentGO:0010720920.021
spindle organizationGO:0007051530.021
response to cytokineGO:00340972320.021
ribonucleoprotein complex subunit organizationGO:0071826810.021
regulation of protein modification by small protein conjugation or removalGO:19033201070.021
positive regulation of protein phosphorylationGO:00019343130.021
negative regulation of protein phosphorylationGO:00019331400.021
monosaccharide metabolic processGO:0005996740.020
nucleoside triphosphate biosynthetic processGO:0009142200.020
syncytium formation by plasma membrane fusionGO:000076820.020
monocarboxylic acid biosynthetic processGO:0072330670.020
pyrimidine nucleotide metabolic processGO:000622060.020
regulation of glucose metabolic processGO:0010906280.020
positive regulation of locomotionGO:00400171860.020
cellular response to glucose stimulusGO:0071333100.020
regulation of protein kinase activityGO:00458592890.020
coagulationGO:0050817780.020
regulation of epidermis developmentGO:0045682190.020
immune responseGO:00069553070.020
negative regulation of cellular component movementGO:00512711060.019
secretionGO:00469032540.019
response to antibioticGO:0046677150.019
regulation of translationGO:0006417890.019
pyrimidine nucleoside triphosphate biosynthetic processGO:000914810.019
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.019
positive regulation of nucleotide biosynthetic processGO:0030810380.019
negative regulation of kinase activityGO:00336731060.019
endocytosisGO:00068971590.019
negative regulation of endopeptidase activityGO:0010951840.019
nuclear exportGO:0051168690.019
protein catabolic processGO:00301633250.019
positive regulation of cell deathGO:00109422630.018
pyrimidine ribonucleoside biosynthetic processGO:004613220.018
regulation of blood coagulationGO:0030193420.018
secretion by cellGO:00329402260.018
response to hexoseGO:0009746200.018
defense response to bacteriumGO:0042742630.018
regulation of anatomical structure morphogenesisGO:00226032860.018
dna repairGO:00062811980.018
erk1 and erk2 cascadeGO:00703711040.018
regulation of intracellular protein transportGO:00331571230.017
response to fatty acidGO:0070542130.017
response to metal ionGO:0010038840.017
cell divisionGO:00513011680.017
striated muscle cell differentiationGO:0051146430.017
embryo developmentGO:00097901230.017
glucose metabolic processGO:0006006450.017
atp metabolic processGO:00460341760.017
anatomical structure homeostasisGO:00602491000.017
hexose metabolic processGO:0019318550.017
negative regulation of cellular catabolic processGO:0031330830.017
transmembrane transportGO:00550853990.016
positive regulation of mapk cascadeGO:00434101900.016
negative regulation of cell cycleGO:00457861930.016
purine nucleoside triphosphate metabolic processGO:00091444120.016
pyrimidine ribonucleoside triphosphate metabolic processGO:000920820.016
pyrimidine containing compound metabolic processGO:0072527190.016
cellular glucose homeostasisGO:0001678110.016
nucleotide phosphorylationGO:0046939150.016
response to abiotic stimulusGO:00096283360.015
positive regulation of organelle organizationGO:00106381950.015
regulation of peptidase activityGO:00525471800.015
regulation of immune responseGO:00507762010.015
ribonucleoside triphosphate biosynthetic processGO:0009201120.015
mononuclear cell proliferationGO:0032943710.015
positive regulation of immune responseGO:00507781590.015
protein methylationGO:0006479740.015
regulation of establishment of protein localizationGO:00702012420.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.015
regulation of proteolysisGO:00301622930.015
myosin filament assemblyGO:003103420.015
ribonucleoprotein complex assemblyGO:0022618780.014
positive regulation of dna metabolic processGO:0051054730.014
cellular protein complex assemblyGO:00436231880.014
muscle cell differentiationGO:0042692630.014
purine nucleoside biosynthetic processGO:0042451230.014
protein localization to nucleusGO:00345041360.014
neuron developmentGO:00486661130.014
response to steroid hormoneGO:0048545800.014
microtubule cytoskeleton organizationGO:00002261760.014
purine nucleoside triphosphate biosynthetic processGO:0009145110.014
protein ubiquitinationGO:00165673140.014
reproductive processGO:00224141060.014
regulation of response to external stimulusGO:00321012220.014
regulation of cell cycle phase transitionGO:19019871260.014
regulation of nervous system developmentGO:0051960880.014
biological adhesionGO:00226103310.013
positive regulation of cell cycleGO:00457871400.013
regulation of dna metabolic processGO:00510521530.013
regulation of protein transportGO:00512232130.013
positive regulation of nucleotide metabolic processGO:00459812300.013
positive regulation of kinase activityGO:00336742040.013
regulation of dna bindingGO:0051101370.013
negative regulation of cell growthGO:0030308830.013
jnk cascadeGO:0007254800.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
regulation of protein stabilityGO:0031647870.013
regulation of lipid metabolic processGO:0019216960.012
chordate embryonic developmentGO:0043009340.012
cellular carbohydrate metabolic processGO:0044262840.012
divalent inorganic cation homeostasisGO:00725071360.012
cellular response to hexose stimulusGO:0071331100.012
cellular response to monosaccharide stimulusGO:0071326100.012
cellular ion homeostasisGO:00068731680.012
positive regulation of cell differentiationGO:00455972110.012
cullin deneddylationGO:001038890.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
striated muscle contractionGO:0006941520.012
regulation of chromosome organizationGO:00330441030.012
modification dependent protein catabolic processGO:00199412090.012
negative regulation of oxidative stress induced cell deathGO:1903202170.012
lipid localizationGO:00108761060.012
t cell activationGO:0042110990.012
inflammatory responseGO:0006954790.012
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.012
negative regulation of transportGO:00510511760.012
negative regulation of intracellular signal transductionGO:19025321830.012
response to radiationGO:00093141510.012
regulation of response to dna damage stimulusGO:2001020940.012
regulation of secretion by cellGO:19035301770.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.011
integrin mediated signaling pathwayGO:0007229320.011
reproductionGO:0000003630.011
secondary metabolic processGO:0019748170.011
lymphocyte activationGO:00466491330.011
peripheral nervous system developmentGO:000742220.011
cellular response to fatty acidGO:007139880.011
ion homeostasisGO:00508012300.011
protein targetingGO:00066051870.011
negative regulation of cell developmentGO:0010721480.011
leukocyte activationGO:00453211640.011
regulation of protein export from nucleusGO:0046825150.011
agingGO:0007568660.011
regulation of ubiquitin protein transferase activityGO:0051438280.011
positive regulation of ion transportGO:0043270870.011
positive regulation of leukocyte migrationGO:0002687460.011
protein alkylationGO:0008213740.011
positive regulation of protein transportGO:00512221350.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
peptidyl serine modificationGO:00182091060.011
nuclear importGO:00511701060.011
pyrimidine nucleoside metabolic processGO:0006213130.011
positive regulation of protein secretionGO:0050714600.011
regulation of nuclear divisionGO:0051783650.010
pyrimidine nucleotide biosynthetic processGO:000622120.010
mitochondrion organizationGO:00070051560.010
cell death in response to oxidative stressGO:0036473290.010
response to hydrogen peroxideGO:0042542400.010
generation of neuronsGO:00486991520.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
positive regulation of secretionGO:00510471160.010
positive regulation of nf kappab transcription factor activityGO:0051092810.010
regulation of cofactor metabolic processGO:005119330.010
cellular response to carbohydrate stimulusGO:0071322110.010
positive regulation of catabolic processGO:00098963100.010
maintenance of locationGO:00512351120.010
positive regulation of cell projection organizationGO:0031346640.010
negative regulation of protein kinase activityGO:0006469980.010
embryo development ending in birth or egg hatchingGO:0009792340.010
regulation of neuron projection developmentGO:0010975570.010
positive regulation of neurogenesisGO:0050769490.010

MIF disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
osteochondrodysplasiaDOID:2256350.035
connective tissue diseaseDOID:651090.035
bone diseaseDOID:0080001880.035
bone development diseaseDOID:0080006550.035
musculoskeletal system diseaseDOID:172230.035
immune system diseaseDOID:29141550.031
acquired metabolic diseaseDOID:0060158580.016
carbohydrate metabolism diseaseDOID:0050013320.016
disease of metabolismDOID:00146672950.016
cancerDOID:1621670.011
disease of cellular proliferationDOID:145661740.011
organ system cancerDOID:00506861640.011