Homo sapiens

74 known processes

SHMT1

serine hydroxymethyltransferase 1 (soluble)

(Aliases: SHMT,CSHMT,MGC15229,MGC24556)

SHMT1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.206
post embryonic developmentGO:000979120.068
oxidation reduction processGO:00551143960.066
small molecule catabolic processGO:0044282920.063
cellular ketone metabolic processGO:0042180800.060
cofactor metabolic processGO:0051186870.059
organonitrogen compound biosynthetic processGO:19015662000.053
cellular modified amino acid metabolic processGO:0006575640.052
lipid metabolic processGO:00066293810.052
amine metabolic processGO:0009308440.048
cellular amine metabolic processGO:0044106410.047
coenzyme metabolic processGO:0006732650.046
cellular lipid metabolic processGO:00442553030.043
response to oxygen containing compoundGO:19017003690.042
regulation of cellular ketone metabolic processGO:0010565500.042
monocarboxylic acid metabolic processGO:00327871850.041
regulation of cellular amino acid metabolic processGO:000652160.040
purine ribonucleoside metabolic processGO:00461284370.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
regulation of cellular amine metabolic processGO:0033238110.034
multicellular organismal agingGO:001025930.034
small molecule biosynthetic processGO:00442831570.033
Rat
carboxylic acid biosynthetic processGO:0046394970.033
Rat
chemical homeostasisGO:00488783060.032
alpha amino acid metabolic processGO:1901605720.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
carbohydrate metabolic processGO:00059752070.032
single organism carbohydrate metabolic processGO:00447231930.031
organophosphate biosynthetic processGO:00904071630.031
determination of adult lifespanGO:000834020.030
protein oligomerizationGO:00512591730.030
positive regulation of cellular amine metabolic processGO:003324070.029
female gamete generationGO:000729220.029
positive regulation of hydrolase activityGO:00513453310.027
mitotic cell cycleGO:00002783260.027
organic acid biosynthetic processGO:0016053970.027
Rat
organic hydroxy compound metabolic processGO:19016151470.027
organophosphate catabolic processGO:00464344300.027
mitotic cell cycle processGO:19030472860.027
nucleoside triphosphate metabolic processGO:00091414220.026
regulation of cell cycleGO:00517263930.026
cellular response to dna damage stimulusGO:00069743790.026
oogenesisGO:004847720.026
response to abiotic stimulusGO:00096283360.025
purine containing compound catabolic processGO:00725234110.025
organic acid catabolic processGO:0016054710.024
ribonucleoside monophosphate metabolic processGO:00091611870.024
negative regulation of catalytic activityGO:00430863350.024
ribonucleotide catabolic processGO:00092614050.024
mitochondrion organizationGO:00070051560.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
locomotory behaviorGO:000762610.023
ras protein signal transductionGO:0007265730.023
purine nucleoside catabolic processGO:00061523980.023
chromatin organizationGO:00063253510.022
nucleoside phosphate catabolic processGO:19012924120.022
protein processingGO:00164852260.022
single organism cellular localizationGO:19025803320.021
negative regulation of phosphate metabolic processGO:00459362670.021
endocytosisGO:00068971590.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
positive regulation of cellular component organizationGO:00511303760.021
regulation of hormone levelsGO:00108171250.020
mitotic nuclear divisionGO:00070671190.020
glycosyl compound catabolic processGO:19016584130.020
defense responseGO:00069523150.020
regulation of proteolysisGO:00301622930.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
transmembrane transportGO:00550853990.020
histone modificationGO:00165702510.020
nucleotide catabolic processGO:00091664080.020
protein catabolic processGO:00301633250.020
purine ribonucleotide catabolic processGO:00091544040.020
negative regulation of phosphorus metabolic processGO:00105632670.020
carbohydrate derivative biosynthetic processGO:19011372070.020
apoptotic signaling pathwayGO:00971902680.020
nucleoside triphosphate catabolic processGO:00091433940.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
nucleoside monophosphate metabolic processGO:00091231910.020
secretionGO:00469032540.020
alcohol metabolic processGO:00060661140.020
maintenance of locationGO:00512351120.020
regulation of immune responseGO:00507762010.019
purine ribonucleoside catabolic processGO:00461303980.019
nucleotide biosynthetic processGO:00091651090.019
regulation of purine nucleotide metabolic processGO:19005422640.019
dna repairGO:00062811980.019
cellular component morphogenesisGO:00329893140.019
cellular amino acid catabolic processGO:0009063310.018
immune responseGO:00069553070.018
membrane organizationGO:00610242920.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
ion homeostasisGO:00508012300.018
nucleoside catabolic processGO:00091644080.018
negative regulation of protein metabolic processGO:00512483910.018
regenerationGO:003109940.018
purine nucleotide catabolic processGO:00061954050.018
small gtpase mediated signal transductionGO:0007264780.018
single organism membrane organizationGO:00448022680.018
cell projection organizationGO:00300302520.018
positive regulation of catabolic processGO:00098963100.018
negative regulation of cellular protein metabolic processGO:00322693530.017
response to biotic stimulusGO:00096072760.017
chromosome segregationGO:00070591140.017
cellular macromolecule catabolic processGO:00442653800.017
fatty acid metabolic processGO:00066311150.017
microtubule based processGO:00070172100.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
vesicle mediated transportGO:00161923710.017
negative regulation of intracellular signal transductionGO:19025321830.017
nitrogen compound transportGO:00717051910.017
carboxylic acid catabolic processGO:0046395710.017
response to external biotic stimulusGO:00432072610.016
cytoplasmic transportGO:00164823790.016
regulation of protein localizationGO:00328802960.016
protein maturationGO:00516042330.016
response to other organismGO:00517072610.016
protein homooligomerizationGO:00512601000.016
Rat
secretion by cellGO:00329402260.016
ribonucleoside catabolic processGO:00424544060.016
neuromuscular junction developmentGO:000752830.016
negative regulation of programmed cell deathGO:00430693210.016
positive regulation of immune system processGO:00026842830.016
hemopoiesisGO:00300971800.016
epithelium developmentGO:00604292270.016
meiotic chromosome segregationGO:004513240.016
regulation of protein kinase activityGO:00458592890.016
lipid biosynthetic processGO:00086101770.015
positive regulation of cellular catabolic processGO:00313312840.015
cellular homeostasisGO:00197251960.015
regulation of transferase activityGO:00513383550.015
regulation of cell cycle processGO:00105642660.015
negative regulation of apoptotic processGO:00430663160.015
anion transportGO:00068201610.015
response to nitrogen compoundGO:19016981840.015
cell morphogenesisGO:00009022960.015
segmentationGO:003528240.014
peripheral nervous system developmentGO:000742220.014
immune system developmentGO:00025201950.014
cellular carbohydrate metabolic processGO:0044262840.014
mitotic cell cycle phase transitionGO:00447721620.014
cellular macromolecular complex assemblyGO:00346223240.014
organelle fissionGO:00482851490.014
positive regulation of phosphorylationGO:00423273940.014
microtubule cytoskeleton organizationGO:00002261760.014
dephosphorylationGO:00163112090.014
ion transmembrane transportGO:00342203380.014
actin filament based processGO:00300292240.014
regulation of peptidase activityGO:00525471800.014
positive regulation of protein phosphorylationGO:00019343130.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of kinase activityGO:00435493140.014
inorganic ion transmembrane transportGO:00986602310.013
spermatid differentiationGO:004851540.013
negative regulation of hydrolase activityGO:00513461820.013
regulation of apoptotic signaling pathwayGO:20012331750.013
cellular response to abiotic stimulusGO:00712141170.013
regulation of cell differentiationGO:00455953930.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
cell projection assemblyGO:00300311260.013
oocyte developmentGO:004859910.013
signal transduction by phosphorylationGO:00230142970.013
covalent chromatin modificationGO:00165692540.013
adult locomotory behaviorGO:000834410.013
negative regulation of protein modification processGO:00314002000.013
regulation of nucleotide metabolic processGO:00061402690.013
oocyte differentiationGO:000999420.013
negative regulation of phosphorylationGO:00423261740.013
intracellular protein transportGO:00068862700.013
sister chromatid segregationGO:0000819540.013
negative regulation of cellular amino acid metabolic processGO:004576320.012
protein tetramerizationGO:0051262470.012
regulation of nucleoside metabolic processGO:00091182090.012
cellular protein complex assemblyGO:00436231880.012
regulation of purine nucleotide catabolic processGO:00331212050.012
atp metabolic processGO:00460341760.012
positive regulation of immune responseGO:00507781590.012
response to lipidGO:00339932060.012
cellular lipid catabolic processGO:0044242650.012
regulation of secretionGO:00510461940.012
memoryGO:000761330.012
positive regulation of programmed cell deathGO:00430682490.012
cellular chemical homeostasisGO:00550821800.012
cell cycle phase transitionGO:00447701730.012
protein localization to organelleGO:00333652800.012
response to fungusGO:000962040.012
innate immune responseGO:00450871780.012
negative regulation of cellular amine metabolic processGO:003323930.012
cation homeostasisGO:00550801890.012
response to inorganic substanceGO:00100351270.012
guanosine containing compound catabolic processGO:19010692390.012
cellular response to endogenous stimulusGO:00714953360.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
positive regulation of cell deathGO:00109422630.012
cell part morphogenesisGO:00329901370.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
mapk cascadeGO:00001652880.012
nucleoside monophosphate catabolic processGO:00091251590.012
positive regulation of nucleotide metabolic processGO:00459812300.012
positive regulation of transportGO:00510503360.012
chromatin modificationGO:00165682980.012
regulation of cellular response to stressGO:00801352440.012
negative regulation of multicellular organismal processGO:00512413170.012
endomembrane system organizationGO:00102561960.012
rho protein signal transductionGO:0007266260.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
negative regulation of cell deathGO:00605483450.012
sulfur compound metabolic processGO:00067901010.011
spermatid developmentGO:000728640.011
reproductive processGO:00224141060.011
negative regulation of transportGO:00510511760.011
regulation of intracellular transportGO:00323861950.011
negative regulation of cell proliferationGO:00082852280.011
negative regulation of protein phosphorylationGO:00019331400.011
cellular protein catabolic processGO:00442572610.011
mitotic sister chromatid segregationGO:0000070530.011
guanosine containing compound metabolic processGO:19010682440.011
organic anion transportGO:00157111030.011
cellular response to cytokine stimulusGO:00713451810.011
regulation of protein maturationGO:19033171500.011
regulation of defense responseGO:00313471540.011
cilium organizationGO:0044782680.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
positive regulation of cell proliferationGO:00082843010.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
protein targetingGO:00066051870.011
methylationGO:00322591060.011
negative regulation of cellular component organizationGO:00511292350.011
positive regulation of developmental processGO:00510943140.011
negative regulation of transferase activityGO:00513481240.011
regulation of ras protein signal transductionGO:00465781550.011
positive regulation of apoptotic processGO:00430652460.011
cellular component disassemblyGO:0022411920.011
cation transportGO:00068123310.011
regulation of multi organism processGO:00439001570.011
lipid catabolic processGO:0016042840.011
system processGO:00030083490.011
regulation of gtpase activityGO:00430871800.011
myeloid cell differentiationGO:00300991170.011
negative regulation of protein processingGO:00109551420.011
cell projection morphogenesisGO:00488581290.011
regulation of protein processingGO:00706131500.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
regulation of protein transportGO:00512232130.010
positive regulation of proteolysisGO:00458621420.010
regulation of protein complex assemblyGO:00432541470.010
response to organic cyclic compoundGO:00140702040.010
regulation of neural precursor cell proliferationGO:200017740.010
posttranscriptional regulation of gene expressionGO:00106082130.010
organelle assemblyGO:00709251760.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
growthGO:00400072020.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
cellular response to oxygen containing compoundGO:19017012760.010
nuclear divisionGO:00002801280.010
organic acid transportGO:0015849650.010
peptide metabolic processGO:0006518510.010
rna splicingGO:00083801310.010
positive regulation of nucleoside metabolic processGO:00459791860.010
response to hormoneGO:00097251750.010
regulation of hormone secretionGO:0046883570.010
regulation of response to external stimulusGO:00321012220.010
negative regulation of cell cycleGO:00457861930.010
reactive oxygen species metabolic processGO:0072593750.010
regulation of anatomical structure morphogenesisGO:00226032860.010
central nervous system developmentGO:00074171230.010
cellular amide metabolic processGO:0043603690.010
gtp metabolic processGO:00460392390.010

SHMT1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.234
disease of metabolismDOID:00146672950.234
amino acid metabolic disorderDOID:9252500.058
disease of cellular proliferationDOID:145661740.037
cancerDOID:1621670.035
organ system cancerDOID:00506861640.031
immune system diseaseDOID:29141550.021
carbohydrate metabolic disorderDOID:2978550.019
glycogen storage diseaseDOID:2747100.017
glycogen metabolism disorderDOID:0050728100.017
central nervous system diseaseDOID:3311860.015
nervous system diseaseDOID:8634310.015
hematopoietic system diseaseDOID:741000.014
musculoskeletal system diseaseDOID:172230.014
sensory system diseaseDOID:00501552030.014
eye and adnexa diseaseDOID:14921500.010