Homo sapiens

10 known processes

PLD3

phospholipase D family, member 3

(Aliases: HUK4,HU-K4)

PLD3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vacuole organizationGO:0007033440.640
negative regulation of collagen catabolic processGO:001071110.432
negative regulation of elastin catabolic processGO:006031110.395
regulation of blood vessel remodelingGO:006031220.363
system processGO:00030083490.329
multicellular organismal homeostasisGO:0048871670.270
cellular homeostasisGO:00197251960.255
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.245
neurological system processGO:00508771630.224
regulation of cellular amine metabolic processGO:0033238110.215
epithelium developmentGO:00604292270.208
negative regulation of multicellular organismal metabolic processGO:004425230.208
anatomical structure homeostasisGO:00602491000.190
cellular amine metabolic processGO:0044106410.186
cellular amino acid metabolic processGO:00065201160.167
negative regulation of extracellular matrix organizationGO:190305430.156
cellular chemical homeostasisGO:00550821800.143
positive regulation of epithelial cell proliferationGO:0050679650.139
multicellular organismal agingGO:001025930.137
chemical homeostasisGO:00488783060.135
g protein coupled receptor signaling pathwayGO:00071862070.131
circulatory system processGO:00030131130.119
circulatory system developmentGO:00723592620.118
regulation of lipid metabolic processGO:0019216960.117
regulation of cellular ketone metabolic processGO:0010565500.109
glycerophospholipid metabolic processGO:0006650840.107
cellular lipid metabolic processGO:00442553030.104
lipid metabolic processGO:00066293810.103
immune system developmentGO:00025201950.102
metal ion transportGO:00300012720.101
positive regulation of cellular amine metabolic processGO:003324070.100
cellular ketone metabolic processGO:0042180800.095
response to biotic stimulusGO:00096072760.094
cellular amide metabolic processGO:0043603690.088
secretion by cellGO:00329402260.086
peripheral nervous system developmentGO:000742220.085
regulation of cellular amino acid metabolic processGO:000652160.085
regulation of mapk cascadeGO:00434082620.084
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.083
negative regulation of phosphate metabolic processGO:00459362670.082
positive regulation of cellular amino acid metabolic processGO:004576430.082
regulation of epithelial cell proliferationGO:00506781130.079
regulation of elastin catabolic processGO:006031010.076
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.076
cellular carbohydrate metabolic processGO:0044262840.076
regulation of secretionGO:00510461940.076
response to oxygen containing compoundGO:19017003690.074
antigen processing and presentationGO:0019882330.074
negative regulation of cellular protein metabolic processGO:00322693530.074
cellular calcium ion homeostasisGO:00068741170.073
positive regulation of cellular component organizationGO:00511303760.073
locomotory behaviorGO:000762610.070
negative regulation of catalytic activityGO:00430863350.070
cyclic nucleotide biosynthetic processGO:0009190610.069
neuromuscular process controlling postureGO:005088420.068
negative regulation of cell deathGO:00605483450.067
signal transduction by phosphorylationGO:00230142970.067
protein maturationGO:00516042330.067
inorganic ion transmembrane transportGO:00986602310.066
determination of adult lifespanGO:000834020.065
amine metabolic processGO:0009308440.063
elastin catabolic processGO:006030910.061
detection of chemical stimulusGO:0009593550.060
proteolysis involved in cellular protein catabolic processGO:00516032440.058
negative regulation of hydrolase activityGO:00513461820.058
protein processingGO:00164852260.058
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.057
modification dependent macromolecule catabolic processGO:00436322120.056
retina development in camera type eyeGO:0060041150.055
cell developmentGO:00484683280.055
transmembrane transportGO:00550853990.055
cation homeostasisGO:00550801890.055
memoryGO:000761330.055
cell type specific apoptotic processGO:00972851250.054
retina homeostasisGO:0001895420.053
neuromuscular processGO:0050905150.052
immune responseGO:00069553070.052
divalent inorganic cation transportGO:00725111580.052
epithelial cell proliferationGO:00506731280.052
negative regulation of catabolic processGO:00098951040.051
positive regulation of cytokine productionGO:00018191670.051
negative regulation of apoptotic processGO:00430663160.050
cell activationGO:00017752130.050
positive regulation of organelle organizationGO:00106381950.049
ion homeostasisGO:00508012300.049
post embryonic developmentGO:000979120.048
response to hormoneGO:00097251750.048
head developmentGO:00603221080.048
ossificationGO:00015031210.048
nervous system developmentGO:00073992930.048
generation of precursor metabolites and energyGO:0006091680.047
azole transportGO:004511740.047
regulation of transferase activityGO:00513383550.046
cellular cation homeostasisGO:00300031630.045
response to oxidative stressGO:00069791210.045
muscle contractionGO:0006936730.045
regulation of cellular response to stressGO:00801352440.045
regulation of system processGO:00440571010.044
regulation of apoptotic signaling pathwayGO:20012331750.044
tissue homeostasisGO:0001894630.044
secretionGO:00469032540.044
organonitrogen compound biosynthetic processGO:19015662000.043
negative regulation of proteolysisGO:00458611320.043
carbohydrate metabolic processGO:00059752070.043
coagulationGO:0050817780.043
glycogen catabolic processGO:000598040.043
sensory perception of chemical stimulusGO:0007606380.043
single organism carbohydrate metabolic processGO:00447231930.042
regulation of kinase activityGO:00435493140.042
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.042
protein localization to organelleGO:00333652800.041
striated muscle contractionGO:0006941520.041
peptidyl tyrosine phosphorylationGO:00181081700.041
positive regulation of developmental processGO:00510943140.041
carbohydrate catabolic processGO:0016052360.041
muscle cell cellular homeostasisGO:004671630.040
negative regulation of blood vessel remodelingGO:006031310.040
mapk cascadeGO:00001652880.040
response to other organismGO:00517072610.040
skeletal muscle contractionGO:0003009160.040
positive regulation of nucleotide biosynthetic processGO:0030810380.040
regulation of protein kinase activityGO:00458592890.040
regulation of proteolysisGO:00301622930.039
central nervous system developmentGO:00074171230.039
cellular ion homeostasisGO:00068731680.039
kidney developmentGO:0001822530.038
regulation of ion transmembrane transportGO:00347651320.038
exocytosisGO:0006887710.038
response to external biotic stimulusGO:00432072610.038
regulation of cell differentiationGO:00455953930.038
detection of stimulusGO:0051606850.037
hematopoietic or lymphoid organ developmentGO:00485341860.036
eye developmentGO:0001654420.036
response to hypoxiaGO:0001666960.036
regulation of vesicle mediated transportGO:00606271300.035
positive regulation of immune system processGO:00026842830.034
negative regulation of programmed cell deathGO:00430693210.034
cell projection organizationGO:00300302520.033
response to woundingGO:00096111680.033
camp metabolic processGO:0046058610.033
positive regulation of phosphorylationGO:00423273940.032
cellular macromolecule catabolic processGO:00442653800.032
lysosome organizationGO:0007040240.032
gland developmentGO:0048732480.032
heart contractionGO:0060047620.032
prostate gland developmentGO:003085030.032
generation of neuronsGO:00486991520.031
inorganic cation transmembrane transportGO:00986621940.031
negative regulation of transferase activityGO:00513481240.031
lytic vacuole organizationGO:0080171240.031
regulation of erk1 and erk2 cascadeGO:0070372990.031
response to extracellular stimulusGO:0009991850.030
peptidyl tyrosine modificationGO:00182121700.030
respiratory system processGO:000301630.030
vesicle mediated transportGO:00161923710.029
response to lipidGO:00339932060.029
glycosyl compound catabolic processGO:19016584130.029
regulation of oxidative stress induced cell deathGO:1903201240.029
urogenital system developmentGO:0001655650.029
negative regulation of dendritic cell differentiationGO:200119920.028
divalent metal ion transportGO:00708381520.028
positive regulation of cell proliferationGO:00082843010.028
regulation of ion transportGO:00432691890.028
neurogenesisGO:00220081690.028
regulation of homeostatic processGO:00328441210.028
regulation of peptidase activityGO:00525471800.028
proteasomal protein catabolic processGO:00104981760.027
membrane organizationGO:00610242920.027
calcium ion transportGO:00068161470.027
maintenance of locationGO:00512351120.027
action potentialGO:0001508340.027
lipid transportGO:0006869900.027
positive regulation of transportGO:00510503360.027
regulation of immune responseGO:00507762010.027
divalent inorganic cation homeostasisGO:00725071360.027
regulation of secretion by cellGO:19035301770.027
membrane protein proteolysisGO:0033619380.027
negative regulation of multicellular organismal processGO:00512413170.026
oxidation reduction processGO:00551143960.026
negative regulation of apoptotic signaling pathwayGO:2001234970.026
regulation of protein processingGO:00706131500.026
carbohydrate derivative biosynthetic processGO:19011372070.026
lipopolysaccharide transportGO:001592020.026
defense responseGO:00069523150.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
regulation of establishment of protein localizationGO:00702012420.025
epithelial cell differentiationGO:00308551410.025
regulation of protein maturationGO:19033171500.025
renal system developmentGO:0072001630.025
cation transportGO:00068123310.025
sensory perception of bitter tasteGO:0050913280.025
calcium ion homeostasisGO:00550741220.025
regulation of cellular component biogenesisGO:00440872810.025
cellular metal ion homeostasisGO:00068751460.025
protein catabolic processGO:00301633250.025
negative regulation of phosphorus metabolic processGO:00105632670.025
organic hydroxy compound transportGO:0015850630.024
response to organic cyclic compoundGO:00140702040.024
maintenance of location in cellGO:0051651620.024
positive regulation of protein phosphorylationGO:00019343130.024
cellular response to extracellular stimulusGO:0031668720.024
rhythmic behaviorGO:000762220.023
response to axon injuryGO:004867810.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.023
negative regulation of kinase activityGO:00336731060.023
chromatin organizationGO:00063253510.023
camp biosynthetic processGO:0006171470.023
modification dependent protein catabolic processGO:00199412090.023
neuron deathGO:0070997650.023
ribonucleotide biosynthetic processGO:0009260810.023
lipid biosynthetic processGO:00086101770.023
positive regulation of cellular component biogenesisGO:00440891580.023
regulation of purine nucleotide metabolic processGO:19005422640.022
blood vessel remodelingGO:000197420.022
diaphragm contractionGO:000208610.022
cellular polysaccharide metabolic processGO:0044264270.022
response to bacteriumGO:00096171440.022
hemopoiesisGO:00300971800.022
regulation of protein transportGO:00512232130.021
response to oxygen levelsGO:00704821000.021
actin filament based processGO:00300292240.021
cellular response to oxygen containing compoundGO:19017012760.021
intracellular protein transportGO:00068862700.021
positive regulation of cell activationGO:0050867810.021
cell morphogenesisGO:00009022960.021
positive regulation of hydrolase activityGO:00513453310.020
negative regulation of immune system processGO:00026831360.020
cytosolic calcium ion homeostasisGO:0051480890.020
positive regulation of kinase activityGO:00336742040.020
growthGO:00400072020.020
regulation of cell developmentGO:00602841610.020
cardiovascular system developmentGO:00723582620.020
negative regulation of protein maturationGO:19033181420.020
nucleoside phosphate biosynthetic processGO:19012931090.020
organophosphate biosynthetic processGO:00904071630.020
mannose metabolic processGO:000601310.020
oogenesisGO:004847720.020
cell death in response to oxidative stressGO:0036473290.020
positive regulation of secretionGO:00510471160.020
ribonucleoside catabolic processGO:00424544060.020
regulation of angiotensin levels in bloodGO:000200230.020
response to hydrogen peroxideGO:0042542400.020
g protein coupled acetylcholine receptor signaling pathwayGO:000721310.020
polysaccharide catabolic processGO:000027240.019
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.019
positive regulation of cellular catabolic processGO:00313312840.019
cellular response to reactive oxygen speciesGO:0034614500.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.019
negative regulation of protein processingGO:00109551420.019
receptor metabolic processGO:0043112810.019
regulation of peptidyl tyrosine phosphorylationGO:00507301080.019
regulation of protein localizationGO:00328802960.019
posttranscriptional regulation of gene expressionGO:00106082130.018
single organism membrane organizationGO:00448022680.018
camera type eye developmentGO:0043010250.018
cytokine productionGO:00018162470.018
ubiquitin dependent protein catabolic processGO:00065112060.018
wnt signaling pathwayGO:00160551560.018
gtp metabolic processGO:00460392390.018
apoptotic signaling pathwayGO:00971902680.018
muscle system processGO:0003012810.018
positive regulation of transferase activityGO:00513472270.018
regulation of defense responseGO:00313471540.018
regulation of blood circulationGO:1903522590.017
regulation of phGO:0006885200.017
guanosine containing compound catabolic processGO:19010692390.017
bone developmentGO:0060348260.017
cellular response to hypoxiaGO:0071456510.017
heart processGO:0003015620.017
monovalent inorganic cation homeostasisGO:0055067370.017
nucleoside catabolic processGO:00091644080.017
canonical wnt signaling pathwayGO:00600701160.017
regulation of systemic arterial blood pressure by hormoneGO:0001990120.017
cellular protein catabolic processGO:00442572610.017
negative regulation of peptidase activityGO:0010466910.016
negative regulation of cellular component organizationGO:00511292350.016
positive regulation of protein serine threonine kinase activityGO:00719021190.016
regulation of exocytosisGO:0017157460.016
negative regulation of cell migrationGO:00303361020.016
neuromuscular process controlling balanceGO:005088570.016
wound healingGO:00420601150.016
sensory organ developmentGO:0007423520.016
metencephalon developmentGO:002203720.016
cellular component morphogenesisGO:00329893140.016
autophagyGO:0006914880.016
positive regulation of catabolic processGO:00098963100.016
regulation of heart contractionGO:0008016500.016
osteoclast developmentGO:003603520.016
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.015
positive regulation of secretion by cellGO:19035321080.015
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.015
polysaccharide metabolic processGO:0005976330.015
cellular component disassemblyGO:0022411920.015
alcohol metabolic processGO:00060661140.015
purine containing compound biosynthetic processGO:0072522880.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of anatomical structure morphogenesisGO:00226032860.015
axon ensheathment in central nervous systemGO:003229110.015
phosphatidic acid biosynthetic processGO:000665440.015
regenerationGO:003109940.015
neural tube patterningGO:002153220.015
positive regulation of immune responseGO:00507781590.015
establishment of blood brain barrierGO:006085610.015
cellular response to endogenous stimulusGO:00714953360.015
ectodermal placode formationGO:006078810.015
cellular response to oxygen levelsGO:0071453550.014
thiamine transportGO:001588830.014
negative regulation of protein kinase activityGO:0006469980.014
response to starvationGO:0042594590.014
innate immune responseGO:00450871780.014
organic hydroxy compound metabolic processGO:19016151470.014
circadian sleep wake cycle processGO:002241020.014
chemical homeostasis within a tissueGO:004887530.014
nucleotide catabolic processGO:00091664080.014
platelet aggregationGO:0070527320.014
ion transmembrane transportGO:00342203380.014
regulation of neuron differentiationGO:0045664700.014
negative regulation of cellular component movementGO:00512711060.014
regulation of nucleotide metabolic processGO:00061402690.014
neuromuscular junction developmentGO:000752830.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
regulation of hormone levelsGO:00108171250.013
neuron apoptotic processGO:0051402390.013
stress activated mapk cascadeGO:0051403930.013
protein targetingGO:00066051870.013
regulation of dna metabolic processGO:00510521530.013
positive regulation of axon extensionGO:004577340.013
peptide metabolic processGO:0006518510.013
single organism cellular localizationGO:19025803320.013
organic acid biosynthetic processGO:0016053970.013
neuronal action potentialGO:001922890.013
negative regulation of cellular catabolic processGO:0031330830.013
female gamete generationGO:000729220.013
reactive oxygen species metabolic processGO:0072593750.013
negative regulation of phosphorylationGO:00423261740.013
single organism reproductive processGO:0044702980.013
phospholipid metabolic processGO:0006644990.013
positive regulation of dna metabolic processGO:0051054730.013
neuron projection developmentGO:00311751060.013
negative regulation of intracellular signal transductionGO:19025321830.013
cell chemotaxisGO:00603261120.013
epidermis developmentGO:0008544590.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of mitotic cell cycleGO:00073461890.013
behaviorGO:00076101120.013
myeloid cell differentiationGO:00300991170.012
protein localization to membraneGO:00726571600.012
negative regulation of cellular response to oxidative stressGO:1900408180.012
regulation of cell migrationGO:00303342890.012
negative regulation of protein metabolic processGO:00512483910.012
cell death in response to hydrogen peroxideGO:0036474100.012
developmental growthGO:0048589480.012
immune effector processGO:00022521590.012
cell part morphogenesisGO:00329901370.012
leukocyte differentiationGO:0002521980.012
brain developmentGO:0007420970.012
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of endocytosisGO:0030100720.012
response to reactive oxygen speciesGO:0000302610.012
purine ribonucleotide biosynthetic processGO:0009152790.012
regulation of endopeptidase activityGO:00525481700.012
positive regulation of cytosolic calcium ion concentrationGO:0007204820.012
sensory perception of tasteGO:0050909360.012
response to decreased oxygen levelsGO:0036293960.012
myeloid leukocyte differentiationGO:0002573600.012
hindbrain developmentGO:003090230.012
small molecule biosynthetic processGO:00442831570.012
embryonic morphogenesisGO:0048598850.011
embryo developmentGO:00097901230.011
tissue remodelingGO:0048771160.011
negative regulation of wnt signaling pathwayGO:0030178690.011
reproductive processGO:00224141060.011
heart morphogenesisGO:0003007480.011
pancreatic juice secretionGO:003015740.011
tor signalingGO:0031929390.011
regulation of body fluid levelsGO:0050878990.011
regulation of nervous system developmentGO:0051960880.011
purine nucleotide catabolic processGO:00061954050.011
regulation of blood pressureGO:0008217300.011
negative regulation of protein phosphorylationGO:00019331400.011
long term memoryGO:000761620.011
single organism carbohydrate catabolic processGO:0044724330.011
skeletal system developmentGO:0001501790.011
regulation of nucleoside metabolic processGO:00091182090.011
neuron differentiationGO:00301821380.011
positive regulation of necrotic cell deathGO:001094040.011
protein homooligomerizationGO:00512601000.011
metal ion homeostasisGO:00550651690.011
regulation of cell cycle processGO:00105642660.011
negative regulation of cellular amine metabolic processGO:003323930.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
mitotic cell cycleGO:00002783260.011
positive regulation of cell differentiationGO:00455972110.011
regulation of ras gtpase activityGO:00323181280.011
reproductive system developmentGO:0061458560.011
negative regulation of locomotionGO:00400131180.011
regulation of neuron deathGO:1901214560.011
cofactor metabolic processGO:0051186870.011
response to abiotic stimulusGO:00096283360.011
somatic stem cell divisionGO:004810310.011
positive regulation of release of cytochrome c from mitochondriaGO:0090200180.011
positive regulation of map kinase activityGO:0043406800.011
regulation of wnt signaling pathwayGO:00301111230.011
organelle assemblyGO:00709251760.011
negative regulation of macrophage activationGO:004303110.010
regulation of cyclic nucleotide metabolic processGO:0030799630.010
regulation of cell motilityGO:20001452990.010
regulation of intracellular transportGO:00323861950.010
negative regulation of developmental processGO:00510932470.010
glucan metabolic processGO:0044042220.010
aminoglycan metabolic processGO:0006022390.010
regulation of nuclear divisionGO:0051783650.010
purine ribonucleotide catabolic processGO:00091544040.010
cellular response to nutrient levelsGO:0031669690.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
regulation of protein tyrosine kinase activityGO:0061097360.010

PLD3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.873
inherited metabolic disorderDOID:6552420.839
lysosomal storage diseaseDOID:3211470.575
cerebral degenerationDOID:1443160.500
nervous system diseaseDOID:8634310.500
central nervous system diseaseDOID:3311860.500
brain diseaseDOID:936730.500
lipid storage diseaseDOID:9455280.429
leukodystrophyDOID:1057980.151
neuronal ceroid lipofuscinosisDOID:14503110.056
glycogen metabolism disorderDOID:0050728100.037
carbohydrate metabolic disorderDOID:2978550.037
vascular diseaseDOID:178250.035
cardiovascular system diseaseDOID:12871060.035
artery diseaseDOID:0050828230.024
gastrointestinal system diseaseDOID:77360.013
mouth diseaseDOID:403140.013
connective tissue diseaseDOID:651090.012
musculoskeletal system diseaseDOID:172230.012
sphingolipidosisDOID:1927140.012
neurodegenerative diseaseDOID:12891020.010
disease of mental healthDOID:150700.004
dementiaDOID:1307190.002
alzheimer s diseaseDOID:10652160.002
tauopathyDOID:680160.002
cognitive disorderDOID:1561290.002