Homo sapiens

0 known processes

SCUBE2

signal peptide, CUB domain, EGF-like 2

(Aliases: CEGP1,CEGB1,FLJ16792,CEGF1,MGC133057,FLJ35234)

SCUBE2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of locomotionGO:00400123290.093
regulation of cell motilityGO:20001452990.092
positive regulation of cell proliferationGO:00082843010.084
cellular ketone metabolic processGO:0042180800.079
regulation of anatomical structure morphogenesisGO:00226032860.078
biological adhesionGO:00226103310.075
enzyme linked receptor protein signaling pathwayGO:00071673030.075
regulation of cellular component movementGO:00512703340.072
positive regulation of cellular component organizationGO:00511303760.069
negative regulation of developmental processGO:00510932470.069
regulation of cell migrationGO:00303342890.068
system processGO:00030083490.068
cell adhesionGO:00071553250.067
post embryonic developmentGO:000979120.066
regulation of cellular amine metabolic processGO:0033238110.064
negative regulation of apoptotic processGO:00430663160.064
positive regulation of cellular amine metabolic processGO:003324070.062
positive regulation of developmental processGO:00510943140.061
lipid metabolic processGO:00066293810.059
negative regulation of programmed cell deathGO:00430693210.057
chemical homeostasisGO:00488783060.057
regulation of cell differentiationGO:00455953930.057
ras protein signal transductionGO:0007265730.056
transmembrane transportGO:00550853990.055
positive regulation of cell differentiationGO:00455972110.055
segmentationGO:003528240.054
positive regulation of protein phosphorylationGO:00019343130.052
positive regulation of phosphorylationGO:00423273940.052
negative regulation of multicellular organismal processGO:00512413170.050
small gtpase mediated signal transductionGO:0007264780.049
cytoplasmic transportGO:00164823790.048
positive regulation of transportGO:00510503360.048
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.047
cell type specific apoptotic processGO:00972851250.047
amine metabolic processGO:0009308440.047
tube developmentGO:00352951250.046
positive regulation of immune system processGO:00026842830.046
positive regulation of cell migrationGO:00303351720.045
regulation of protein localizationGO:00328802960.045
cellular amino acid metabolic processGO:00065201160.044
regulation of protein transportGO:00512232130.044
regulation of cellular amino acid metabolic processGO:000652160.044
ossificationGO:00015031210.044
negative regulation of cellular component organizationGO:00511292350.043
anatomical structure formation involved in morphogenesisGO:00486462840.043
regulation of cellular ketone metabolic processGO:0010565500.043
cellular lipid metabolic processGO:00442553030.043
positive regulation of hydrolase activityGO:00513453310.042
regulation of cell adhesionGO:00301551660.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
mapk cascadeGO:00001652880.042
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.041
intracellular protein transportGO:00068862700.041
ribonucleoside catabolic processGO:00424544060.041
positive regulation of mapk cascadeGO:00434101900.040
blood vessel developmentGO:00015681720.040
regulation of kinase activityGO:00435493140.040
regulation of hormone levelsGO:00108171250.040
cardiovascular system developmentGO:00723582620.039
oogenesisGO:004847720.039
positive regulation of locomotionGO:00400171860.039
cation transportGO:00068123310.039
anion transportGO:00068201610.038
cell developmentGO:00484683280.038
cell morphogenesisGO:00009022960.038
regulation of cell cycleGO:00517263930.038
metal ion transportGO:00300012720.038
negative regulation of cell proliferationGO:00082852280.038
positive regulation of cell motilityGO:20001471770.038
regulation of growthGO:00400081650.038
cellular amine metabolic processGO:0044106410.038
female gamete generationGO:000729220.037
growthGO:00400072020.037
epithelium developmentGO:00604292270.037
vasculature developmentGO:00019441810.037
negative regulation of cell deathGO:00605483450.037
regulation of protein kinase activityGO:00458592890.036
signal transduction by phosphorylationGO:00230142970.036
regulation of cytokine productionGO:00018172320.036
positive regulation of apoptotic processGO:00430652460.035
cytokine productionGO:00018162470.035
regulation of cell developmentGO:00602841610.035
multicellular organismal agingGO:001025930.035
determination of adult lifespanGO:000834020.035
single organism cellular localizationGO:19025803320.034
regulation of mapk cascadeGO:00434082620.034
rho protein signal transductionGO:0007266260.034
ribonucleotide catabolic processGO:00092614050.034
hindbrain developmentGO:003090230.034
circulatory system developmentGO:00723592620.033
purine ribonucleoside metabolic processGO:00461284370.033
regulation of nucleotide metabolic processGO:00061402690.033
cellular component morphogenesisGO:00329893140.033
blastoderm segmentationGO:000735020.033
negative regulation of transportGO:00510511760.033
organophosphate catabolic processGO:00464344300.033
ion transmembrane transportGO:00342203380.032
non canonical wnt signaling pathway via mapk cascadeGO:003803040.032
vesicle mediated transportGO:00161923710.032
metal ion homeostasisGO:00550651690.032
purine nucleoside catabolic processGO:00061523980.032
ion homeostasisGO:00508012300.032
anterior posterior axis specificationGO:000994820.032
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.032
cellular response to endogenous stimulusGO:00714953360.031
regulation of cell growthGO:00015581350.031
nucleoside catabolic processGO:00091644080.031
response to oxygen containing compoundGO:19017003690.031
nervous system developmentGO:00073992930.031
negative regulation of locomotionGO:00400131180.031
epithelial cell differentiationGO:00308551410.030
regulation of transferase activityGO:00513383550.030
defense responseGO:00069523150.030
protein localization to organelleGO:00333652800.030
secretionGO:00469032540.030
anterior posterior axis specification embryoGO:000859520.030
response to lipidGO:00339932060.030
regulation of establishment of protein localizationGO:00702012420.030
positive regulation of protein kinase activityGO:00458601900.030
negative regulation of catalytic activityGO:00430863350.030
purine nucleotide catabolic processGO:00061954050.030
positive regulation of catabolic processGO:00098963100.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
nucleotide catabolic processGO:00091664080.029
negative regulation of cell migrationGO:00303361020.029
positive regulation of cellular component movementGO:00512721810.029
nucleoside phosphate catabolic processGO:19012924120.029
oxidation reduction processGO:00551143960.029
inorganic ion transmembrane transportGO:00986602310.029
carbohydrate metabolic processGO:00059752070.029
positive regulation of cell deathGO:00109422630.028
dephosphorylationGO:00163112090.028
cell growthGO:00160491600.028
single organism cell adhesionGO:00986021790.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.028
positive regulation of programmed cell deathGO:00430682490.028
positive regulation of transferase activityGO:00513472270.028
regulation of cellular response to stressGO:00801352440.028
regenerationGO:003109940.028
purine containing compound catabolic processGO:00725234110.028
positive regulation of cellular catabolic processGO:00313312840.027
locomotory behaviorGO:000762610.027
lung alveolus developmentGO:004828640.027
gtp catabolic processGO:00061842370.027
actin filament based processGO:00300292240.027
regulation of purine nucleotide metabolic processGO:19005422640.027
negative regulation of cell differentiationGO:00455961710.027
negative regulation of phosphate metabolic processGO:00459362670.027
response to other organismGO:00517072610.027
regulation of secretionGO:00510461940.027
purine ribonucleoside catabolic processGO:00461303980.027
carbohydrate derivative biosynthetic processGO:19011372070.027
actin cytoskeleton organizationGO:00300362070.027
negative regulation of protein metabolic processGO:00512483910.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
cellular homeostasisGO:00197251960.026
response to growth factorGO:00708482050.026
canonical wnt signaling pathwayGO:00600701160.026
protein maturationGO:00516042330.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
response to organic cyclic compoundGO:00140702040.026
regulation of cell cycle processGO:00105642660.026
negative regulation of cell cycleGO:00457861930.026
cellular divalent inorganic cation homeostasisGO:00725031280.026
response to external biotic stimulusGO:00432072610.026
response to hormoneGO:00097251750.025
purine ribonucleotide catabolic processGO:00091544040.025
regulation of proteolysisGO:00301622930.025
regulation of intracellular protein transportGO:00331571230.025
response to woundingGO:00096111680.025
regulation of cellular component biogenesisGO:00440872810.025
negative regulation of cellular protein metabolic processGO:00322693530.025
regulation of small gtpase mediated signal transductionGO:00510561560.025
regulation of intracellular transportGO:00323861950.025
wound healingGO:00420601150.025
regulation of response to external stimulusGO:00321012220.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
negative regulation of phosphorus metabolic processGO:00105632670.025
tripartite regional subdivisionGO:000735120.025
nitrogen compound transportGO:00717051910.025
guanosine containing compound catabolic processGO:19010692390.025
protein targetingGO:00066051870.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
positive regulation of kinase activityGO:00336742040.024
innate immune responseGO:00450871780.024
regulation of ion transportGO:00432691890.024
cellular chemical homeostasisGO:00550821800.024
prostate gland morphogenesisGO:006051210.024
neurogenesisGO:00220081690.024
organ morphogenesisGO:00098871470.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
immune responseGO:00069553070.024
response to biotic stimulusGO:00096072760.023
monocarboxylic acid metabolic processGO:00327871850.023
positive regulation of protein transportGO:00512221350.023
neuron fate commitmentGO:004866320.023
cell projection organizationGO:00300302520.023
cation transmembrane transportGO:00986552380.023
apoptotic signaling pathwayGO:00971902680.023
positive regulation of nucleotide metabolic processGO:00459812300.022
neuromuscular junction developmentGO:000752830.022
osteoblast differentiationGO:0001649920.022
secretion by cellGO:00329402260.022
guanosine containing compound metabolic processGO:19010682440.022
oocyte developmentGO:004859910.022
mitotic cell cycle processGO:19030472860.022
wnt signaling pathwayGO:00160551560.022
positive regulation of erk1 and erk2 cascadeGO:0070374750.022
cellular cation homeostasisGO:00300031630.022
response to abiotic stimulusGO:00096283360.022
cyclic nucleotide metabolic processGO:0009187820.022
mitotic cell cycleGO:00002783260.021
nucleoside triphosphate metabolic processGO:00091414220.021
nucleocytoplasmic transportGO:00069131760.021
protein processingGO:00164852260.021
nucleoside triphosphate catabolic processGO:00091433940.021
morphogenesis of embryonic epitheliumGO:001633140.021
protein modification by small protein conjugationGO:00324463420.021
regulation of secretion by cellGO:19035301770.021
regulation of neural precursor cell proliferationGO:200017740.021
negative regulation of cell adhesionGO:0007162640.021
protein ubiquitinationGO:00165673140.021
positive regulation of cytokine productionGO:00018191670.021
cell fate determinationGO:000170930.021
regulation of wnt signaling pathwayGO:00301111230.021
single organism membrane organizationGO:00448022680.021
organonitrogen compound biosynthetic processGO:19015662000.021
hormone metabolic processGO:0042445610.021
multicellular organismal response to stressGO:003355510.021
positive regulation of organelle organizationGO:00106381950.021
divalent metal ion transportGO:00708381520.020
membrane organizationGO:00610242920.020
nuclear transportGO:00511691790.020
cellular metal ion homeostasisGO:00068751460.020
organic anion transportGO:00157111030.020
negative regulation of cell fate specificationGO:000999630.020
positive regulation of neural precursor cell proliferationGO:200017920.020
lipid biosynthetic processGO:00086101770.020
regulation of sodium dependent phosphate transportGO:200011820.020
positive regulation of cell developmentGO:0010720920.020
cellular response to dna damage stimulusGO:00069743790.020
peripheral nervous system developmentGO:000742220.020
regulation of angiogenesisGO:0045765920.020
regulation of mitotic cell cycleGO:00073461890.020
oocyte differentiationGO:000999420.019
single organismal cell cell adhesionGO:00163371480.019
response to cytokineGO:00340972320.019
blood vessel morphogenesisGO:00485141620.019
memoryGO:000761330.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of cell morphogenesisGO:00226041530.019
cation homeostasisGO:00550801890.019
negative regulation of cell fate commitmentGO:001045430.019
protein catabolic processGO:00301633250.019
regulation of cytoplasmic transportGO:19036491490.019
negative regulation of organelle organizationGO:00106391260.019
glycosyl compound catabolic processGO:19016584130.019
single organism carbohydrate metabolic processGO:00447231930.019
negative regulation of cellular component movementGO:00512711060.019
generation of neuronsGO:00486991520.019
regulation of nucleoside metabolic processGO:00091182090.019
epithelial cell proliferationGO:00506731280.019
regulation of odontogenesisGO:004248140.019
regulation of neuron differentiationGO:0045664700.018
retina vasculature morphogenesis in camera type eyeGO:006129930.018
angiogenesisGO:00015251470.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
cellular ion homeostasisGO:00068731680.018
embryonic epithelial tube formationGO:000183840.018
regulation of epithelial cell proliferationGO:00506781130.018
cell activationGO:00017752130.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.018
establishment of protein localization to organelleGO:00725941720.018
inner ear morphogenesisGO:004247240.018
regulation of anatomical structure sizeGO:00900661010.018
cellular response to organic cyclic compoundGO:00714071270.018
circulatory system processGO:00030131130.018
regulation of protein serine threonine kinase activityGO:00719001790.018
digestive tract developmentGO:0048565750.018
positive regulation of ras gtpase activityGO:00323201170.018
neurological system processGO:00508771630.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
muscle structure developmentGO:0061061980.018
cell substrate adhesionGO:00315891320.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of nucleotide catabolic processGO:00308112050.018
divalent inorganic cation transportGO:00725111580.018
regulation of ras protein signal transductionGO:00465781550.018
cellular macromolecule catabolic processGO:00442653800.018
positive regulation of gtpase activityGO:00435471660.018
neuron differentiationGO:00301821380.018
regulation of cytoskeleton organizationGO:00514931770.018
negative regulation of growthGO:0045926970.018
positive regulation of nucleotide catabolic processGO:00308131850.018
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of gtpase activityGO:00430871800.018
negative regulation of embryonic developmentGO:004599240.017
brain developmentGO:0007420970.017
protein localization to nucleusGO:00345041360.017
non canonical wnt signaling pathway via jnk cascadeGO:003803130.017
gtp metabolic processGO:00460392390.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of cell projection organizationGO:00313441070.017
tube morphogenesisGO:0035239950.017
response to inorganic substanceGO:00100351270.017
calcium ion transportGO:00068161470.017
ameboidal type cell migrationGO:00016671350.017
prostate gland developmentGO:003085030.017
compound eye developmentGO:004874910.017
regulation of immune responseGO:00507762010.017
urogenital system developmentGO:0001655650.017
taxisGO:00423301570.017
g protein coupled receptor signaling pathwayGO:00071862070.017
regulation of axon guidanceGO:190266730.017
positive regulation of protein serine threonine kinase activityGO:00719021190.017
tissue regenerationGO:004224630.017
digestive system developmentGO:0055123750.017
regulation of ras gtpase activityGO:00323181280.017
negative regulation of wnt signaling pathwayGO:0030178690.017
tissue morphogenesisGO:0048729960.017
small molecule biosynthetic processGO:00442831570.017
central nervous system developmentGO:00074171230.017
forelimb morphogenesisGO:003513640.016
cell part morphogenesisGO:00329901370.016
protein localization to membraneGO:00726571600.016
cellular response to oxygen containing compoundGO:19017012760.016
regulation of apoptotic signaling pathwayGO:20012331750.016
spemann organizer formationGO:006006110.016
mammary gland morphogenesisGO:006044320.016
spermatid differentiationGO:004851540.016
chemotaxisGO:00069351570.016
negative regulation of cell growthGO:0030308830.016
positive regulation of intracellular transportGO:00323881040.016
protein oligomerizationGO:00512591730.016
Human
regulation of dna metabolic processGO:00510521530.016
positive regulation of epithelial cell proliferationGO:0050679650.016
regulation of axon extension involved in axon guidanceGO:004884120.016
motor neuron axon guidanceGO:000804520.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
hemopoiesisGO:00300971800.016
negative regulation of phosphorylationGO:00423261740.016
positive regulation of immune responseGO:00507781590.016
neuron projection regenerationGO:003110210.016
regulation of transmembrane transportGO:00347621390.016
regulation of peptidase activityGO:00525471800.016
regulation of protein maturationGO:19033171500.016
specification of organ identityGO:001009230.016
somatic stem cell maintenanceGO:003501940.016
regulation of map kinase activityGO:00434051080.016
regulation of defense responseGO:00313471540.016
endomembrane system organizationGO:00102561960.016
sex determinationGO:000753030.016
metencephalon developmentGO:002203720.015
organophosphate biosynthetic processGO:00904071630.015
endocytosisGO:00068971590.015
negative regulation of gastrulationGO:200054240.015
cell morphogenesis involved in differentiationGO:00009041440.015
renal system developmentGO:0072001630.015
steroid metabolic processGO:0008202940.015
cell cell signalingGO:00072671550.015
spinal cord developmentGO:002151040.015
cell divisionGO:00513011680.015
regulation of canonical wnt signaling pathwayGO:0060828880.015
epithelial cell migrationGO:00106311190.015
negative regulation of axonogenesisGO:005077140.015
organelle assemblyGO:00709251760.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
leukocyte activationGO:00453211640.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
cellular protein catabolic processGO:00442572610.015
regulation of actin cytoskeleton organizationGO:00329561160.015
chromatin organizationGO:00063253510.015
regulation of gtp catabolic processGO:00331241800.015
protein targeting to nucleusGO:00447441040.015
sulfur compound metabolic processGO:00067901010.015
hindlimb morphogenesisGO:003513720.015
positive regulation of nucleoside metabolic processGO:00459791860.015
biomineral tissue developmentGO:0031214390.015
stem cell differentiationGO:0048863930.015
neurotransmitter secretionGO:000726940.015
calcium ion homeostasisGO:00550741220.015
response to axon injuryGO:004867810.015
matingGO:000761810.015
regulation of protein processingGO:00706131500.015
positive regulation of proteolysisGO:00458621420.015
regulation of endopeptidase activityGO:00525481700.015
cellular protein complex assemblyGO:00436231880.015
regulation of vasculature developmentGO:1901342970.015
positive regulation of secretionGO:00510471160.015
immune system developmentGO:00025201950.015
response to steroid hormoneGO:0048545800.015
stem cell developmentGO:0048864690.015
regulation of protein catabolic processGO:00421761550.014
protein importGO:00170381300.014
kidney developmentGO:0001822530.014
positive regulation of gtp catabolic processGO:00331261660.014
response to nitrogen compoundGO:19016981840.014
cyclic purine nucleotide metabolic processGO:0052652600.014
fatty acid metabolic processGO:00066311150.014
stem cell divisionGO:001714520.014
regulation of transporter activityGO:0032409820.014
negative regulation of apoptotic signaling pathwayGO:2001234970.014
nuclear importGO:00511701060.014
cellular amide metabolic processGO:0043603690.014
regulation of bindingGO:00510981110.014
negative regulation of gliogenesisGO:001401430.014
inorganic cation transmembrane transportGO:00986621940.014
chromatin modificationGO:00165682980.014
glycoprotein metabolic processGO:00091001100.014
neural tube patterningGO:002153220.014
regulation of cell activationGO:00508651250.014
regulation of cell divisionGO:00513021160.014
receptor metabolic processGO:0043112810.014
cell cycle phase transitionGO:00447701730.014
nucleotide biosynthetic processGO:00091651090.014
negative regulation of cell motilityGO:20001461040.014
regulation of nucleocytoplasmic transportGO:0046822980.014
cellular calcium ion homeostasisGO:00068741170.014
epithelium migrationGO:00901321190.014
negative regulation of synaptic transmissionGO:005080520.014
regulation of nervous system developmentGO:0051960880.014
embryonic morphogenesisGO:0048598850.014
regulation of cardiac muscle tissue growthGO:005502140.014
organic hydroxy compound metabolic processGO:19016151470.014
immune effector processGO:00022521590.014
negative regulation of canonical wnt signaling pathwayGO:0090090550.014
reactive oxygen species biosynthetic processGO:190340940.014
erk1 and erk2 cascadeGO:00703711040.014
pituitary gland developmentGO:002198320.014
negative regulation of protein modification processGO:00314002000.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
peptidyl tyrosine modificationGO:00182121700.014
proteasomal protein catabolic processGO:00104981760.014
cardiac muscle cell contractionGO:008600340.014
rhythmic behaviorGO:000762220.014
adult locomotory behaviorGO:000834410.014
glycoprotein biosynthetic processGO:0009101910.013
positive regulation of secretion by cellGO:19035321080.013
maintenance of locationGO:00512351120.013
cellular response to growth factor stimulusGO:00713631970.013
positive regulation of intracellular protein transportGO:0090316760.013
cell aggregationGO:009874310.013
regulation of multi organism processGO:00439001570.013
regulation of response to woundingGO:19030341010.013
spermatid developmentGO:000728640.013
peptidyl tyrosine phosphorylationGO:00181081700.013
negative regulation of immune system processGO:00026831360.013
t cell differentiation in thymusGO:003307740.013
response to bacteriumGO:00096171440.013
regulation of actin filament based processGO:00329701410.013
syncytium formation by plasma membrane fusionGO:000076820.013
cellular response to lipidGO:00713961270.013
negative regulation of catabolic processGO:00098951040.013
monosaccharide metabolic processGO:0005996740.013
negative regulation of cell cycle processGO:00109481210.013
divalent inorganic cation homeostasisGO:00725071360.013
regulation of protein import into nucleusGO:0042306780.013
multicellular organismal homeostasisGO:0048871670.013
carboxylic acid transportGO:0046942630.013
regulation of body fluid levelsGO:0050878990.013
mitotic cell cycle phase transitionGO:00447721620.013
neural tube formationGO:000184130.013
regulation of erk1 and erk2 cascadeGO:0070372990.013
blood circulationGO:00080151130.013
patterning of blood vesselsGO:000156920.013
regulation of protein localization to nucleusGO:1900180850.013
receptor internalizationGO:0031623430.013
regulation of endothelial cell differentiationGO:004560140.013
activation of protein kinase activityGO:0032147900.013
positive regulation of cellular component biogenesisGO:00440891580.013
posttranscriptional regulation of gene expressionGO:00106082130.013
retina vasculature development in camera type eyeGO:006129830.013
tongue developmentGO:004358610.013
organelle fissionGO:00482851490.013
salivary gland morphogenesisGO:000743540.013
single organism nuclear importGO:19025931040.013
forebrain neuron differentiationGO:002187930.013

SCUBE2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.032
nervous system diseaseDOID:8634310.032
central nervous system diseaseDOID:3311860.030
eye and adnexa diseaseDOID:14921500.023
eye diseaseDOID:56141490.022
disease of metabolismDOID:00146672950.021
cancerDOID:1621670.019
disease of cellular proliferationDOID:145661740.019
musculoskeletal system diseaseDOID:172230.018
neurodegenerative diseaseDOID:12891020.018
organ system cancerDOID:00506861640.017
inherited metabolic disorderDOID:6552420.017
connective tissue diseaseDOID:651090.015
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.013