Homo sapiens

55 known processes

PPIB

peptidylprolyl isomerase B (cyclophilin B)

(Aliases: MGC2224,CYPB,CYP-S1,MGC14109,SCYLP,OI9)

PPIB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to unfolded proteinGO:0006986240.751
chaperone mediated protein foldingGO:0061077130.604
4 hydroxyproline metabolic processGO:001947150.585
response to endoplasmic reticulum stressGO:0034976490.491
er nucleus signaling pathwayGO:0006984230.459
endoplasmic reticulum unfolded protein responseGO:0030968160.455
modification dependent macromolecule catabolic processGO:00436322120.376
proteolysis involved in cellular protein catabolic processGO:00516032440.347
regulation of wnt protein secretionGO:006135610.342
monocarboxylic acid metabolic processGO:00327871850.310
cellular response to unfolded proteinGO:0034620160.310
glycoprotein biosynthetic processGO:0009101910.241
regulation of cell migrationGO:00303342890.214
er associated ubiquitin dependent protein catabolic processGO:0030433310.191
regulation of growthGO:00400081650.178
ubiquitin dependent protein catabolic processGO:00065112060.161
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.158
post embryonic developmentGO:000979120.151
cellular response to topologically incorrect proteinGO:0035967190.128
growthGO:00400072020.126
glycoprotein metabolic processGO:00091001100.122
positive regulation of blood pressureGO:004577730.110
regulation of behaviorGO:0050795820.097
positive regulation of developmental processGO:00510943140.096
cellular modified amino acid metabolic processGO:0006575640.087
protein n linked glycosylationGO:0006487230.084
maintenance of locationGO:00512351120.077
apoptotic signaling pathwayGO:00971902680.076
regulation of cell motilityGO:20001452990.075
cellular macromolecule catabolic processGO:00442653800.074
positive regulation of cellular component organizationGO:00511303760.072
cellular protein catabolic processGO:00442572610.072
positive regulation of growthGO:0045927580.072
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.070
protein glycosylationGO:0006486620.069
response to topologically incorrect proteinGO:0035966290.062
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.061
regulation of proteolysisGO:00301622930.060
intracellular protein transportGO:00068862700.060
cytoplasmic transportGO:00164823790.057
posttranscriptional regulation of gene expressionGO:00106082130.056
regulation of apoptotic signaling pathwayGO:20012331750.055
cell chemotaxisGO:00603261120.052
determination of adult lifespanGO:000834020.051
negative regulation of apoptotic processGO:00430663160.050
regulation of locomotionGO:00400123290.049
cellular ketone metabolic processGO:0042180800.049
single organism carbohydrate metabolic processGO:00447231930.049
cellular amino acid metabolic processGO:00065201160.047
response to oxygen containing compoundGO:19017003690.047
glycosylationGO:0070085710.047
carbohydrate derivative biosynthetic processGO:19011372070.047
carbohydrate metabolic processGO:00059752070.046
response to organic cyclic compoundGO:00140702040.045
negative regulation of programmed cell deathGO:00430693210.043
single organism membrane organizationGO:00448022680.043
cellular response to endogenous stimulusGO:00714953360.042
cellular amine metabolic processGO:0044106410.041
oxidation reduction processGO:00551143960.041
regulation of cell growthGO:00015581350.041
positive regulation of phosphorylationGO:00423273940.041
positive regulation of multicellular organism growthGO:004001860.041
regulation of cellular amino acid metabolic processGO:000652160.040
response to decreased oxygen levelsGO:0036293960.040
proteasomal protein catabolic processGO:00104981760.039
regulation of leukocyte chemotaxisGO:0002688460.039
positive regulation of protein phosphorylationGO:00019343130.038
rna interferenceGO:001624640.036
protein foldingGO:0006457380.036
response to cytokineGO:00340972320.035
regulation of cell adhesionGO:00301551660.035
response to hypoxiaGO:0001666960.034
vesicle mediated transportGO:00161923710.034
regulation of multi organism processGO:00439001570.034
multicellular organismal agingGO:001025930.033
positive regulation of transportGO:00510503360.033
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.033
lipid localizationGO:00108761060.031
single organism cell adhesionGO:00986021790.030
negative regulation of hydrolase activityGO:00513461820.030
leukocyte activationGO:00453211640.030
establishment of protein localization to membraneGO:00901501210.030
positive regulation of cell deathGO:00109422630.030
regulation of cysteine type endopeptidase activityGO:20001161270.029
alpha amino acid metabolic processGO:1901605720.029
male sex differentiationGO:0046661250.027
cytokinesisGO:0000910960.026
regulation of establishment of protein localizationGO:00702012420.025
hindbrain developmentGO:003090230.024
negative regulation of catalytic activityGO:00430863350.024
cellular homeostasisGO:00197251960.024
protein maturationGO:00516042330.023
developmental growthGO:0048589480.023
peptidyl glutamic acid modificationGO:001820040.023
regulation of gtp catabolic processGO:00331241800.023
vitamin metabolic processGO:0006766260.023
cellular response to organonitrogen compoundGO:00714171240.023
purine nucleoside catabolic processGO:00061523980.023
positive regulation of dna metabolic processGO:0051054730.022
regulation of response to oxidative stressGO:1902882260.022
embryo developmentGO:00097901230.022
regulation of cell cycle processGO:00105642660.022
cellular response to transforming growth factor beta stimulusGO:0071560940.021
male genitalia developmentGO:003053910.021
regulation of peptidase activityGO:00525471800.021
regulation of membrane potentialGO:0042391950.021
positive regulation of programmed cell deathGO:00430682490.021
purine ribonucleotide catabolic processGO:00091544040.021
lymphocyte activationGO:00466491330.020
response to abiotic stimulusGO:00096283360.020
peptidyl tyrosine modificationGO:00182121700.020
locomotory behaviorGO:000762610.020
membrane organizationGO:00610242920.020
circulatory system processGO:00030131130.020
negative regulation of cellular protein metabolic processGO:00322693530.019
protein catabolic processGO:00301633250.019
protein localization to organelleGO:00333652800.019
positive regulation of developmental growthGO:0048639160.019
t cell activationGO:0042110990.019
regulation of cell divisionGO:00513021160.019
cellular response to external stimulusGO:00714961110.019
cellular response to oxidative stressGO:0034599850.019
regulation of cell cycleGO:00517263930.019
regulation of cellular response to stressGO:00801352440.018
regulation of protein kinase activityGO:00458592890.018
wnt protein secretionGO:006135510.018
cell activationGO:00017752130.018
positive regulation of cellular amine metabolic processGO:003324070.018
chemotaxisGO:00069351570.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
reactive nitrogen species metabolic processGO:200105730.017
regulation of cellular component movementGO:00512703340.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
actin filament organizationGO:00070151280.017
negative regulation of cell deathGO:00605483450.017
establishment of protein localization to endoplasmic reticulumGO:0072599110.017
response to inorganic substanceGO:00100351270.016
blood circulationGO:00080151130.016
protein hydroxylationGO:001812690.016
response to starvationGO:0042594590.016
cell death in response to oxidative stressGO:0036473290.016
cellular response to organic cyclic compoundGO:00714071270.016
response to hormoneGO:00097251750.016
protein localization to nucleusGO:00345041360.016
embryo development ending in birth or egg hatchingGO:0009792340.016
microtubule cytoskeleton organizationGO:00002261760.016
regulation of body fluid levelsGO:0050878990.016
synaptic vesicle recyclingGO:003646530.016
regulation of endocytosisGO:0030100720.015
regulation of cellular ketone metabolic processGO:0010565500.015
negative regulation of protein processingGO:00109551420.015
negative regulation of cell cycleGO:00457861930.015
positive regulation of kinase activityGO:00336742040.015
positive regulation of protein secretionGO:0050714600.015
regulation of gene expression epigeneticGO:0040029730.015
negative regulation of phosphorus metabolic processGO:00105632670.015
reproductionGO:0000003630.015
Fly
macromolecule glycosylationGO:0043413630.015
agingGO:0007568660.015
regenerationGO:003109940.014
regulation of sequestering of calcium ionGO:0051282410.014
nervous system developmentGO:00073992930.014
negative regulation of multicellular organismal processGO:00512413170.014
cytosolic calcium ion transportGO:0060401480.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
negative regulation of apoptotic signaling pathwayGO:2001234970.014
negative regulation of catabolic processGO:00098951040.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
positive regulation of secretionGO:00510471160.014
regulation of protein processingGO:00706131500.014
regulation of kinase activityGO:00435493140.014
regulation of chemotaxisGO:0050920740.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
peptidyl asparagine modificationGO:0018196110.014
regulation of protein secretionGO:0050708860.014
cell divisionGO:00513011680.013
regulation of vesicle mediated transportGO:00606271300.013
embryonic placenta developmentGO:000189210.013
single organism cellular localizationGO:19025803320.013
system processGO:00030083490.013
regulation of cellular amine metabolic processGO:0033238110.013
peptidyl cysteine modificationGO:001819890.013
response to toxic substanceGO:0009636370.013
receptor mediated endocytosisGO:0006898840.013
negative regulation of phosphate metabolic processGO:00459362670.013
neurogenesisGO:00220081690.013
nucleocytoplasmic transportGO:00069131760.013
posttranslational protein targeting to membraneGO:000662050.012
reactive oxygen species metabolic processGO:0072593750.012
fatty acid metabolic processGO:00066311150.012
extracellular structure organizationGO:0043062410.012
heat acclimationGO:001028630.012
regulation of protein localizationGO:00328802960.012
response to transforming growth factor betaGO:0071559940.012
cellular response to hormone stimulusGO:00328701250.012
positive regulation of cellular component movementGO:00512721810.012
cellular protein complex assemblyGO:00436231880.012
lipid storageGO:0019915280.012
regulation of cellular protein catabolic processGO:1903362960.012
positive regulation of transferase activityGO:00513472270.012
mitotic cell cycle phase transitionGO:00447721620.012
positive regulation of immune system processGO:00026842830.011
developmental process involved in reproductionGO:0003006660.011
negative regulation of growthGO:0045926970.011
regulation of proteasomal protein catabolic processGO:0061136870.011
vesicle organizationGO:0016050620.011
peptide cross linkingGO:0018149120.011
positive regulation of cell proliferationGO:00082843010.011
primary neural tube formationGO:001402030.011
sequestering of calcium ionGO:0051208170.011
protein export from nucleusGO:0006611290.011
regulation of developmental growthGO:0048638300.011
regulation of systemic arterial blood pressureGO:0003073190.011
cellular response to oxygen containing compoundGO:19017012760.011
response to external biotic stimulusGO:00432072610.011
neuron differentiationGO:00301821380.011
negative regulation of synaptic transmissionGO:005080520.010
reactive oxygen species biosynthetic processGO:190340940.010
positive regulation of mapk cascadeGO:00434101900.010
positive regulation of locomotionGO:00400171860.010
protein targetingGO:00066051870.010
glycoprotein catabolic processGO:000651670.010
regulation of purine nucleotide metabolic processGO:19005422640.010
organic acid biosynthetic processGO:0016053970.010
regulation of bindingGO:00510981110.010
regulation of dna replicationGO:0006275680.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
cytosolic calcium ion homeostasisGO:0051480890.010
retina layer formationGO:001084230.010
regulation of meiosisGO:004002030.010

PPIB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.029
disease of cellular proliferationDOID:145661740.029
cancerDOID:1621670.029
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.017
musculoskeletal system diseaseDOID:172230.017
myelomaDOID:007000470.013
bone marrow cancerDOID:4960100.013
hematologic cancerDOID:2531360.013
immune system cancerDOID:0060083360.013
bone development diseaseDOID:0080006550.001
osteochondrodysplasiaDOID:2256350.001
osteogenesis imperfectaDOID:12347130.001