Homo sapiens

228 known processes

PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

(Aliases: UBL5,DOD)

PIN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517263930.987
response to abiotic stimulusGO:00096283360.670
cellular response to dna damage stimulusGO:00069743790.618
cell developmentGO:00484683280.617
regulation of locomotionGO:00400123290.458
post embryonic developmentGO:000979120.409
attachment of gpi anchor to proteinGO:001625510.351
female gamete generationGO:000729220.350
ncrna metabolic processGO:00346601080.350
regulation of mapk cascadeGO:00434082620.337
locomotory behaviorGO:000762610.334
neural tube formationGO:000184130.317
ribonucleotide catabolic processGO:00092614050.311
posttranscriptional regulation of gene expressionGO:00106082130.308
matingGO:000761810.304
trna processingGO:0008033230.296
positive regulation of catabolic processGO:00098963100.283
ribonucleoside catabolic processGO:00424544060.279
nervous system developmentGO:00073992930.272
oogenesisGO:004847720.268
chromatin modificationGO:00165682980.263
positive regulation of protein catabolic processGO:0045732750.259
lipid metabolic processGO:00066293810.255
organelle fissionGO:00482851490.249
nucleoside phosphate catabolic processGO:19012924120.249
ras protein signal transductionGO:0007265730.245
ribonucleoprotein complex biogenesisGO:00226131160.244
intracellular protein transportGO:00068862700.238
organ morphogenesisGO:00098871470.213
embryonic morphogenesisGO:0048598850.206
ribosome biogenesisGO:0042254480.196
neural crest cell developmentGO:001403230.195
primary neural tube formationGO:001402030.193
regulation of mitosisGO:0007088630.189
mrna metabolic processGO:00160711750.188
protein import into nucleusGO:00066061040.186
purine ribonucleotide catabolic processGO:00091544040.184
negative regulation of cell cycle phase transitionGO:1901988890.183
purine nucleoside catabolic processGO:00061523980.180
protein localization to organelleGO:00333652800.174
response to radiationGO:00093141510.168
cell cycle phase transitionGO:00447701730.165
response to nitrogen compoundGO:19016981840.163
regulation of cellular response to stressGO:00801352440.162
cell divisionGO:00513011680.162
embryo developmentGO:00097901230.160
protein modification by small protein conjugationGO:00324463420.159
nucleotide catabolic processGO:00091664080.159
regulation of cell cycle processGO:00105642660.159
regulation of immune responseGO:00507762010.159
production of mirnas involved in gene silencing by mirnaGO:0035196120.157
regulation of membrane potentialGO:0042391950.157
mitotic cell cycle processGO:19030472860.155
positive regulation of phosphorylationGO:00423273940.151
negative regulation of catalytic activityGO:00430863350.151
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.147
regulation of gene expression epigeneticGO:0040029730.146
rhythmic behaviorGO:000762220.142
cell cycle checkpointGO:00000751170.142
stem cell developmentGO:0048864690.138
small gtpase mediated signal transductionGO:0007264780.137
interspecies interaction between organismsGO:00444191560.137
negative regulation of mitotic cell cycleGO:00459301020.134
regulation of cell motilityGO:20001452990.134
protein targetingGO:00066051870.124
dna damage checkpointGO:0000077680.122
establishment of protein localization to organelleGO:00725941720.118
chromosome segregationGO:00070591140.118
oocyte differentiationGO:000999420.117
base conversion or substitution editingGO:001655340.117
negative regulation of phosphorus metabolic processGO:00105632670.116
negative regulation of mitotic cell cycle phase transitionGO:1901991850.111
chordate embryonic developmentGO:0043009340.105
monovalent inorganic cation transportGO:00156721280.104
purine nucleoside monophosphate catabolic processGO:00091281580.104
negative regulation of protein modification processGO:00314002000.104
response to cytokineGO:00340972320.103
nuclear exportGO:0051168690.101
regulation of transferase activityGO:00513383550.101
protein importGO:00170381300.101
cellular component morphogenesisGO:00329893140.100
chromatin organizationGO:00063253510.096
vesicle mediated transportGO:00161923710.096
regulation of mitotic cell cycleGO:00073461890.095
purine nucleoside triphosphate catabolic processGO:00091463920.095
dna integrity checkpointGO:0031570710.095
neurogenesisGO:00220081690.091
regulation of protein ubiquitinationGO:0031396950.090
posttranscriptional gene silencing by rnaGO:0035194250.089
ncrna processingGO:0034470830.089
negative regulation of chromosome organizationGO:2001251480.087
positive regulation of mapk cascadeGO:00434101900.087
visual behaviorGO:000763220.083
apoptotic signaling pathwayGO:00971902680.083
mesenchymal cell differentiationGO:0048762520.083
circadian behaviorGO:004851220.082
neuron apoptotic processGO:0051402390.081
response to decreased oxygen levelsGO:0036293960.081
skeletal system developmentGO:0001501790.080
purine ribonucleoside triphosphate metabolic processGO:00092054110.079
regulation of cell divisionGO:00513021160.078
single organism cellular localizationGO:19025803320.078
protein targeting to nucleusGO:00447441040.078
endocytosisGO:00068971590.078
mitotic cell cycle checkpointGO:0007093680.078
regulation of transmembrane transporter activityGO:0022898740.077
regulation of protein catabolic processGO:00421761550.077
negative regulation of phosphate metabolic processGO:00459362670.077
cellular macromolecule catabolic processGO:00442653800.077
maintenance of locationGO:00512351120.076
mitotic cell cycle phase transitionGO:00447721620.074
regulation of viral genome replicationGO:0045069480.073
cellular response to organic cyclic compoundGO:00714071270.073
positive regulation of protein phosphorylationGO:00019343130.073
organophosphate catabolic processGO:00464344300.072
single organism membrane organizationGO:00448022680.071
negative regulation of cell proliferationGO:00082852280.070
adenosine to inosine editingGO:000638230.070
cytokinesisGO:0000910960.070
regulation of epithelial cell proliferationGO:00506781130.069
cellular response to endogenous stimulusGO:00714953360.069
protein localization to nucleusGO:00345041360.068
positive regulation of cellular catabolic processGO:00313312840.068
response to oxygen containing compoundGO:19017003690.067
cytoplasmic transportGO:00164823790.067
regulation of multi organism processGO:00439001570.065
oocyte developmentGO:004859910.065
nucleoside triphosphate catabolic processGO:00091433940.064
embryonic skeletal system developmentGO:0048706130.063
gene silencing by rnaGO:0031047260.063
regulation of protein modification by small protein conjugation or removalGO:19033201070.062
purine ribonucleoside catabolic processGO:00461303980.062
response to organic cyclic compoundGO:00140702040.062
negative regulation of cellular protein metabolic processGO:00322693530.062
negative regulation of cell cycle processGO:00109481210.061
stem cell differentiationGO:0048863930.061
receptor mediated endocytosisGO:0006898840.061
positive regulation of hydrolase activityGO:00513453310.060
ribonucleoprotein complex subunit organizationGO:0071826810.060
protein catabolic processGO:00301633250.060
calcium ion homeostasisGO:00550741220.058
limbic system developmentGO:002176130.058
multicellular organismal agingGO:001025930.058
ribonucleoside triphosphate metabolic processGO:00091994120.057
histone modificationGO:00165702510.057
regulation of cell migrationGO:00303342890.057
mesenchyme developmentGO:0060485590.057
autophagyGO:0006914880.057
embryo development ending in birth or egg hatchingGO:0009792340.055
regulation of proteolysisGO:00301622930.054
gtp catabolic processGO:00061842370.054
adult locomotory behaviorGO:000834410.054
lipoprotein metabolic processGO:0042157420.053
rrna processingGO:0006364350.052
cellular response to nitrogen compoundGO:19016991440.052
mitotic cell cycleGO:00002783260.052
positive regulation of viral processGO:0048524370.052
cardiovascular system developmentGO:00723582620.051
regulation of cell cycle phase transitionGO:19019871260.051
organophosphate biosynthetic processGO:00904071630.050
regulation of cellular component movementGO:00512703340.050
regulation of growthGO:00400081650.050
regulation of nuclear divisionGO:0051783650.049
nuclear importGO:00511701060.049
multi organism cellular processGO:00447641560.048
response to hypoxiaGO:0001666960.048
dna replicationGO:00062601160.047
actin filament based processGO:00300292240.047
g2 dna damage checkpointGO:0031572260.047
purine nucleotide catabolic processGO:00061954050.046
epithelium developmentGO:00604292270.045
atp catabolic processGO:00062001570.045
intrinsic apoptotic signaling pathwayGO:00971931270.044
regulation of small gtpase mediated signal transductionGO:00510561560.044
glycosyl compound catabolic processGO:19016584130.044
response to oxidative stressGO:00069791210.043
embryonic epithelial tube formationGO:000183840.043
ion homeostasisGO:00508012300.043
divalent inorganic cation homeostasisGO:00725071360.043
nuclear transportGO:00511691790.043
hematopoietic or lymphoid organ developmentGO:00485341860.042
gene silencingGO:0016458490.042
negative regulation of cellular component movementGO:00512711060.042
protein ubiquitinationGO:00165673140.041
circulatory system developmentGO:00723592620.041
associative learningGO:000830610.040
regulation of cell growthGO:00015581350.040
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.040
positive regulation of apoptotic processGO:00430652460.040
regulation of apoptotic signaling pathwayGO:20012331750.039
visual learningGO:000854210.038
lipoprotein biosynthetic processGO:0042158330.038
response to oxygen levelsGO:00704821000.038
negative regulation of protein metabolic processGO:00512483910.038
guanosine containing compound catabolic processGO:19010692390.038
multicellular organism reproductionGO:0032504420.037
regulation of protein localizationGO:00328802960.037
multicellular organismal reproductive processGO:0048609400.037
developmental process involved in reproductionGO:0003006660.037
rho protein signal transductionGO:0007266260.037
microtubule based processGO:00070172100.036
cellular chemical homeostasisGO:00550821800.036
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.036
positive regulation of proteolysisGO:00458621420.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
cell type specific apoptotic processGO:00972851250.036
regulation of viral processGO:00507921030.035
single organism reproductive processGO:0044702980.035
reproductive processGO:00224141060.035
negative regulation of cell cycleGO:00457861930.035
regenerationGO:003109940.035
purine containing compound catabolic processGO:00725234110.035
mitotic nuclear divisionGO:00070671190.034
positive regulation of cellular amine metabolic processGO:003324070.034
regulation of kinase activityGO:00435493140.034
cellular divalent inorganic cation homeostasisGO:00725031280.034
nuclear divisionGO:00002801280.034
regulation of mitotic sister chromatid segregationGO:0033047270.033
regulation of proteasomal protein catabolic processGO:0061136870.033
signal transduction by phosphorylationGO:00230142970.033
cellular amine metabolic processGO:0044106410.033
negative regulation of neuron apoptotic processGO:0043524230.033
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.032
microtubule cytoskeleton organizationGO:00002261760.032
regulation of intracellular transportGO:00323861950.032
regulation of cell developmentGO:00602841610.032
gpi anchor metabolic processGO:0006505110.031
epithelial cell proliferationGO:00506731280.031
generation of neuronsGO:00486991520.031
regulation of cellular amine metabolic processGO:0033238110.031
dna dependent dna replicationGO:0006261440.031
glycolipid biosynthetic processGO:0009247120.031
negative regulation of cell deathGO:00605483450.031
lipid biosynthetic processGO:00086101770.030
negative regulation of transferase activityGO:00513481240.030
cellular metal ion homeostasisGO:00068751460.030
trna metabolic processGO:0006399350.030
regulation of endopeptidase activityGO:00525481700.029
regulation of cellular ketone metabolic processGO:0010565500.029
nucleic acid phosphodiester bond hydrolysisGO:00903051020.029
mitotic dna damage checkpointGO:0044773280.029
negative regulation of protein processingGO:00109551420.029
regulation of chromosome organizationGO:00330441030.028
cellular ketone metabolic processGO:0042180800.028
spermatid differentiationGO:004851540.028
viral life cycleGO:00190581320.028
peptidyl lysine acetylationGO:00183941010.027
negative regulation of hydrolase activityGO:00513461820.027
regulation of cellular component biogenesisGO:00440872810.027
regulation of protein serine threonine kinase activityGO:00719001790.027
viral processGO:00160321460.027
extrinsic apoptotic signaling pathwayGO:00971911190.027
negative regulation of apoptotic processGO:00430663160.027
proteasomal protein catabolic processGO:00104981760.027
amine metabolic processGO:0009308440.026
regulation of actin filament based processGO:00329701410.026
protein lipidationGO:0006497330.026
regulation of circadian rhythmGO:0042752110.026
tube closureGO:006060630.026
regulation of ras protein signal transductionGO:00465781550.026
protein export from nucleusGO:0006611290.026
purine ribonucleoside metabolic processGO:00461284370.026
ribonucleoside monophosphate catabolic processGO:00091581580.026
regulation of gtp catabolic processGO:00331241800.025
cell morphogenesis involved in differentiationGO:00009041440.025
mapk cascadeGO:00001652880.025
regulation of metal ion transportGO:00109591200.025
cellular calcium ion homeostasisGO:00068741170.025
steroid metabolic processGO:0008202940.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
regulation of mitotic cell cycle phase transitionGO:19019901180.025
cell morphogenesisGO:00009022960.025
lens development in camera type eyeGO:000208820.025
posttranscriptional gene silencingGO:0016441250.025
viral genome replicationGO:0019079500.025
cation transportGO:00068123310.024
positive regulation of dna metabolic processGO:0051054730.024
nucleoside catabolic processGO:00091644080.024
regulation of cytoplasmic transportGO:19036491490.024
positive regulation of cell differentiationGO:00455972110.024
sexual reproductionGO:0019953370.024
morphogenesis of an epitheliumGO:0002009600.023
cellular ion homeostasisGO:00068731680.023
response to organonitrogen compoundGO:00102431560.023
homeostasis of number of cellsGO:0048872400.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
regulation of vesicle mediated transportGO:00606271300.023
regulation of neuron differentiationGO:0045664700.022
telencephalon developmentGO:0021537170.022
response to ionizing radiationGO:0010212650.022
negative regulation of kinase activityGO:00336731060.022
nucleocytoplasmic transportGO:00069131760.022
negative regulation of proteolysisGO:00458611320.022
rna modificationGO:0009451270.022
regulation of response to dna damage stimulusGO:2001020940.022
regulation of dna replicationGO:0006275680.022
dna repairGO:00062811980.022
hippocampus developmentGO:002176610.022
nucleoside triphosphate metabolic processGO:00091414220.022
chromosome separationGO:0051304230.022
protein localization to membraneGO:00726571600.021
regulation of neuron deathGO:1901214560.021
protein oligomerizationGO:00512591730.021
response to other organismGO:00517072610.021
atp metabolic processGO:00460341760.021
protein acetylationGO:00064731160.021
cell cell signalingGO:00072671550.021
mitotic sister chromatid segregationGO:0000070530.021
cell growthGO:00160491600.021
regulation of cellular protein catabolic processGO:1903362960.020
negative regulation of intracellular signal transductionGO:19025321830.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
positive regulation of transferase activityGO:00513472270.020
regulation of dna metabolic processGO:00510521530.020
positive regulation of cell deathGO:00109422630.020
developmental programmed cell deathGO:001062330.020
organelle localizationGO:0051640840.020
spindle checkpointGO:0031577260.020
regulation of neuron apoptotic processGO:0043523350.020
morphogenesis of embryonic epitheliumGO:001633140.019
single organism nuclear importGO:19025931040.019
histone phosphorylationGO:0016572160.019
growthGO:00400072020.019
negative regulation of protein kinase activityGO:0006469980.019
response to virusGO:00096151260.019
cell projection organizationGO:00300302520.019
multi organism reproductive processGO:0044703540.018
covalent chromatin modificationGO:00165692540.018
regulation of cell differentiationGO:00455953930.018
determination of adult lifespanGO:000834020.018
positive regulation of dna replicationGO:0045740350.018
positive regulation of endopeptidase activityGO:0010950840.018
negative regulation of cellular component organizationGO:00511292350.018
regulation of excitatory postsynaptic membrane potentialGO:006007910.018
negative regulation of apoptotic signaling pathwayGO:2001234970.018
negative regulation of protein kinase activity by regulation of protein phosphorylationGO:004438750.018
monocarboxylic acid metabolic processGO:00327871850.018
response to lipidGO:00339932060.017
cellular lipid metabolic processGO:00442553030.017
rhythmic processGO:0048511310.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
guanosine containing compound metabolic processGO:19010682440.017
protein heterooligomerizationGO:0051291160.017
purine ribonucleoside monophosphate catabolic processGO:00091691580.017
cellular amino acid metabolic processGO:00065201160.017
mitotic dna integrity checkpointGO:0044774300.017
cell agingGO:0007569520.017
inorganic cation transmembrane transportGO:00986621940.017
regulation of synaptic plasticityGO:004816730.017
negative regulation of cell growthGO:0030308830.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
positive regulation of multi organism processGO:0043902560.017
regulation of cellular amino acid metabolic processGO:000652160.017
rna interferenceGO:001624640.017
rrna metabolic processGO:0016072400.017
regulation of protein kinase b signalingGO:0051896610.016
cellular response to oxygen containing compoundGO:19017012760.016
sex differentiationGO:0007548450.016
negative regulation of growthGO:0045926970.016
cation homeostasisGO:00550801890.016
purine nucleoside triphosphate metabolic processGO:00091444120.016
negative regulation of phosphorylationGO:00423261740.016
positive regulation of transportGO:00510503360.016
neuron differentiationGO:00301821380.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
reproductionGO:0000003630.016
embryonic organ developmentGO:0048568360.016
circadian rhythmGO:0007623210.015
agingGO:0007568660.015
regulation of transporter activityGO:0032409820.015
segmentationGO:003528240.015
regulation of protein kinase activityGO:00458592890.015
regulation of autophagyGO:0010506520.015
muscle structure developmentGO:0061061980.015
regulation of bindingGO:00510981110.015
organonitrogen compound biosynthetic processGO:19015662000.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
regulation of response to external stimulusGO:00321012220.015
system processGO:00030083490.015
positive regulation of gtpase activityGO:00435471660.015
cation transmembrane transportGO:00986552380.015
cellular macromolecular complex assemblyGO:00346223240.015
actin cytoskeleton organizationGO:00300362070.015
positive regulation of organelle organizationGO:00106381950.015
regulation of wnt signaling pathwayGO:00301111230.015
response to hormoneGO:00097251750.015
protein homooligomerizationGO:00512601000.015
glycerophospholipid metabolic processGO:0006650840.015
response to heatGO:0009408210.015
negative regulation of protein ubiquitinationGO:0031397350.014
defense responseGO:00069523150.014
negative regulation of macroautophagyGO:001624240.014
nucleotide excision repairGO:0006289310.014
ubiquitin dependent protein catabolic processGO:00065112060.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
positive regulation of developmental processGO:00510943140.014
regulation of purine nucleotide catabolic processGO:00331212050.014
regulation of nervous system developmentGO:0051960880.014
sodium ion transportGO:0006814610.014
negative regulation of smoothened signaling pathwayGO:004587930.014
reproductive system developmentGO:0061458560.014
gene silencing by mirnaGO:0035195230.014
endomembrane system organizationGO:00102561960.013
regulation of protein acetylationGO:1901983250.013
negative regulation of organelle organizationGO:00106391260.013
response to external biotic stimulusGO:00432072610.013
organelle assemblyGO:00709251760.013
cytokine mediated signaling pathwayGO:00192211090.013
regulation of sister chromatid segregationGO:0033045270.013
negative regulation of epithelial cell proliferationGO:0050680480.013
protein acylationGO:00435431380.013
negative regulation of bindingGO:0051100570.013
negative regulation of programmed cell deathGO:00430693210.013
cell projection morphogenesisGO:00488581290.013
multi multicellular organism processGO:0044706180.013
epithelial cell differentiationGO:00308551410.013
cellular component disassemblyGO:0022411920.012
negative regulation of catabolic processGO:00098951040.012
regulation of peptidase activityGO:00525471800.012
cell adhesionGO:00071553250.012
establishment or maintenance of cell polarityGO:0007163310.012
synaptic transmission cholinergicGO:000727120.012
metaphase anaphase transition of cell cycleGO:0044784210.012
regulation of histone modificationGO:0031056470.012
ion transmembrane transportGO:00342203380.012
neuron deathGO:0070997650.012
positive regulation of programmed cell deathGO:00430682490.012
negative regulation of cellular catabolic processGO:0031330830.012
regulation of rho gtpase activityGO:0032319660.012
metal ion transportGO:00300012720.012
mitotic sister chromatid separationGO:0051306180.012
muscle system processGO:0003012810.012
spermatid developmentGO:000728640.012
negative regulation of protein bindingGO:0032091350.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
rna catabolic processGO:0006401710.012
cellular homeostasisGO:00197251960.012
fear responseGO:004259600.012
regulation of cellular component sizeGO:0032535820.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
sister chromatid segregationGO:0000819540.012
epithelial tube morphogenesisGO:0060562380.012
response to mechanical stimulusGO:0009612510.012
mitotic g2 dna damage checkpointGO:000709570.012
positive regulation of cysteine type endopeptidase activityGO:2001056790.012
motor neuron axon guidanceGO:000804520.011
reactive oxygen species metabolic processGO:0072593750.011
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.011
regulation of rho protein signal transductionGO:0035023790.011
regulation of dna dependent dna replicationGO:0090329190.011
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103030.011
dephosphorylationGO:00163112090.011
regulation of cytoskeleton organizationGO:00514931770.011
multicellular organismal response to stressGO:003355510.011
regulation of cell morphogenesisGO:00226041530.011
establishment or maintenance of monopolar cell polarityGO:006133910.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
tube developmentGO:00352951250.011
response to biotic stimulusGO:00096072760.011
cell part morphogenesisGO:00329901370.011
meiosis iGO:000712740.011
regulation of gtpase activityGO:00430871800.011
potassium ion transportGO:0006813620.011
chromatin remodelingGO:0006338550.011
positive regulation of nucleotide catabolic processGO:00308131850.011
regulation of anatomical structure sizeGO:00900661010.011
positive regulation of nucleotide metabolic processGO:00459812300.011
cell fate determinationGO:000170930.010
development of primary sexual characteristicsGO:0045137350.010
dsrna fragmentationGO:0031050130.010
positive regulation of cell cycleGO:00457871400.010
positive regulation of gtp catabolic processGO:00331261660.010
positive regulation of cell cycle processGO:00900681060.010
proteolysis involved in cellular protein catabolic processGO:00516032440.010
genetic imprintingGO:007151410.010
negative regulation of transportGO:00510511760.010
establishment of nucleus localizationGO:004002310.010

PIN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.039
endocrine gland cancerDOID:170260.033
cancerDOID:1621670.033
organ system cancerDOID:00506861640.033
nervous system diseaseDOID:8634310.012
idiopathic generalized epilepsyDOID:1827210.012
brain diseaseDOID:936730.012
epilepsy syndromeDOID:1826410.012
central nervous system diseaseDOID:3311860.012