Homo sapiens

0 known processes

PURB

purine-rich element binding protein B

(Aliases: MGC126786,PURBETA,MGC126784)

PURB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.308
locomotory behaviorGO:000762610.245
multicellular organismal agingGO:001025930.140
protein ubiquitinationGO:00165673140.121
female gamete generationGO:000729220.120
posttranscriptional regulation of gene expressionGO:00106082130.107
cell morphogenesisGO:00009022960.102
oogenesisGO:004847720.100
cell developmentGO:00484683280.099
cellular component morphogenesisGO:00329893140.096
nervous system developmentGO:00073992930.091
ras protein signal transductionGO:0007265730.091
regulation of cell differentiationGO:00455953930.089
cell projection organizationGO:00300302520.088
growthGO:00400072020.087
purine ribonucleotide catabolic processGO:00091544040.080
positive regulation of developmental processGO:00510943140.077
regulation of cellular amine metabolic processGO:0033238110.074
purine containing compound catabolic processGO:00725234110.071
ribonucleoside triphosphate metabolic processGO:00091994120.071
determination of adult lifespanGO:000834020.070
regulation of anatomical structure morphogenesisGO:00226032860.067
purine nucleotide catabolic processGO:00061954050.067
generation of neuronsGO:00486991520.066
organophosphate catabolic processGO:00464344300.065
cellular ketone metabolic processGO:0042180800.064
purine ribonucleoside metabolic processGO:00461284370.063
nucleoside phosphate catabolic processGO:19012924120.063
neuromuscular junction developmentGO:000752830.063
purine ribonucleoside triphosphate metabolic processGO:00092054110.062
nucleoside catabolic processGO:00091644080.061
ribonucleotide catabolic processGO:00092614050.061
ribonucleoside catabolic processGO:00424544060.060
positive regulation of cell proliferationGO:00082843010.060
regulation of cell cycleGO:00517263930.060
regulation of cellular ketone metabolic processGO:0010565500.058
negative regulation of developmental processGO:00510932470.057
negative regulation of protein metabolic processGO:00512483910.057
purine ribonucleoside triphosphate catabolic processGO:00092073910.054
glycosyl compound catabolic processGO:19016584130.053
negative regulation of multicellular organismal processGO:00512413170.053
purine nucleoside catabolic processGO:00061523980.052
cellular amino acid metabolic processGO:00065201160.051
regulation of cell cycle processGO:00105642660.051
regulation of cellular component biogenesisGO:00440872810.051
purine nucleoside triphosphate metabolic processGO:00091444120.050
cell morphogenesis involved in differentiationGO:00009041440.049
purine nucleoside triphosphate catabolic processGO:00091463920.049
negative regulation of cell deathGO:00605483450.048
rna processingGO:00063962550.048
amine metabolic processGO:0009308440.048
lipid metabolic processGO:00066293810.048
cell cell signalingGO:00072671550.047
nucleoside triphosphate catabolic processGO:00091433940.047
cellular amine metabolic processGO:0044106410.047
cell projection morphogenesisGO:00488581290.047
negative regulation of programmed cell deathGO:00430693210.046
nucleotide catabolic processGO:00091664080.046
small gtpase mediated signal transductionGO:0007264780.046
regulation of translationGO:0006417890.045
vesicle mediated transportGO:00161923710.045
neurogenesisGO:00220081690.044
adult locomotory behaviorGO:000834410.044
anatomical structure formation involved in morphogenesisGO:00486462840.043
chromatin modificationGO:00165682980.043
purine ribonucleoside catabolic processGO:00461303980.043
regulation of apoptotic signaling pathwayGO:20012331750.042
protein catabolic processGO:00301633250.041
neuron projection developmentGO:00311751060.041
segmentationGO:003528240.041
negative regulation of cellular protein metabolic processGO:00322693530.040
regulation of cellular amino acid metabolic processGO:000652160.040
actin filament based processGO:00300292240.040
mitotic cell cycleGO:00002783260.040
neuron differentiationGO:00301821380.040
mitotic cell cycle processGO:19030472860.039
regulation of protein localizationGO:00328802960.039
negative regulation of cellular component organizationGO:00511292350.039
defense responseGO:00069523150.039
regulation of cellular component movementGO:00512703340.038
cytoplasmic transportGO:00164823790.038
response to biotic stimulusGO:00096072760.038
positive regulation of cellular component organizationGO:00511303760.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
cell part morphogenesisGO:00329901370.036
protein modification by small protein conjugationGO:00324463420.036
regulation of growthGO:00400081650.036
cellular macromolecule catabolic processGO:00442653800.035
neuron developmentGO:00486661130.035
cellular response to endogenous stimulusGO:00714953360.033
apoptotic signaling pathwayGO:00971902680.033
positive regulation of cell differentiationGO:00455972110.033
anterior posterior axis specificationGO:000994820.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
negative regulation of apoptotic processGO:00430663160.033
response to abiotic stimulusGO:00096283360.033
positive regulation of protein phosphorylationGO:00019343130.032
organelle assemblyGO:00709251760.032
response to oxygen containing compoundGO:19017003690.032
cell growthGO:00160491600.032
cell cycle phase transitionGO:00447701730.032
guanosine containing compound catabolic processGO:19010692390.031
intrinsic apoptotic signaling pathwayGO:00971931270.031
nucleoside triphosphate metabolic processGO:00091414220.031
oocyte developmentGO:004859910.031
regenerationGO:003109940.031
regulation of cell growthGO:00015581350.031
positive regulation of phosphorylationGO:00423273940.031
positive regulation of transportGO:00510503360.030
immune responseGO:00069553070.030
blastoderm segmentationGO:000735020.030
spermatid differentiationGO:004851540.030
rna interferenceGO:001624640.029
mrna metabolic processGO:00160711750.029
positive regulation of cellular catabolic processGO:00313312840.029
compound eye developmentGO:004874910.029
interspecies interaction between organismsGO:00444191560.029
regulation of cellular response to stressGO:00801352440.029
rho protein signal transductionGO:0007266260.028
proteasomal protein catabolic processGO:00104981760.028
protein acetylationGO:00064731160.028
negative regulation of cell cycleGO:00457861930.028
spermatid developmentGO:000728640.028
single organism cellular localizationGO:19025803320.028
intracellular mrna localizationGO:000829810.027
behaviorGO:00076101120.027
rhythmic behaviorGO:000762220.027
positive regulation of catabolic processGO:00098963100.027
regulation of nucleotide metabolic processGO:00061402690.027
regulation of nervous system developmentGO:0051960880.027
multi organism cellular processGO:00447641560.027
regulation of cell morphogenesisGO:00226041530.027
regulation of protein transportGO:00512232130.027
cellular macromolecular complex assemblyGO:00346223240.026
wnt signaling pathwayGO:00160551560.026
cell fate determinationGO:000170930.026
regulation of mitotic cell cycleGO:00073461890.026
reproductive processGO:00224141060.026
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.026
regulation of intracellular transportGO:00323861950.026
regulation of multi organism processGO:00439001570.026
oocyte differentiationGO:000999420.026
memoryGO:000761330.026
regulation of nucleoside metabolic processGO:00091182090.026
regulation of proteolysisGO:00301622930.026
epithelium developmentGO:00604292270.025
ribonucleoprotein complex biogenesisGO:00226131160.025
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.025
actin cytoskeleton organizationGO:00300362070.025
negative regulation of catalytic activityGO:00430863350.025
chemotaxisGO:00069351570.025
limbic system developmentGO:002176130.025
chromatin organizationGO:00063253510.025
purine nucleoside monophosphate metabolic processGO:00091261860.025
regulation of cell developmentGO:00602841610.025
positive regulation of apoptotic processGO:00430652460.024
cation transportGO:00068123310.024
embryo developmentGO:00097901230.024
Worm
rna splicingGO:00083801310.024
viral processGO:00160321460.024
regulation of protein processingGO:00706131500.024
cellular lipid metabolic processGO:00442553030.024
hindbrain developmentGO:003090230.024
mitotic cell cycle phase transitionGO:00447721620.023
ion homeostasisGO:00508012300.023
regulation of ras protein signal transductionGO:00465781550.023
negative regulation of intracellular signal transductionGO:19025321830.023
tube developmentGO:00352951250.023
system processGO:00030083490.023
regulation of viral processGO:00507921030.022
translationGO:00064121320.022
guanosine containing compound metabolic processGO:19010682440.022
protein acylationGO:00435431380.022
membrane organizationGO:00610242920.022
regulation of cell cycle phase transitionGO:19019871260.022
negative regulation of protein maturationGO:19033181420.022
cellular homeostasisGO:00197251960.022
negative regulation of hydrolase activityGO:00513461820.022
cardiovascular system developmentGO:00723582620.022
regulation of purine nucleotide metabolic processGO:19005422640.022
regulation of gene expression epigeneticGO:0040029730.021
positive regulation of cell deathGO:00109422630.021
biological adhesionGO:00226103310.021
blood vessel morphogenesisGO:00485141620.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
neurological system processGO:00508771630.021
response to other organismGO:00517072610.021
histone modificationGO:00165702510.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
cellular protein catabolic processGO:00442572610.021
regulation of protein maturationGO:19033171500.021
negative regulation of protein processingGO:00109551420.021
pattern specification processGO:0007389430.021
microtubule cytoskeleton organizationGO:00002261760.021
rna catabolic processGO:0006401710.021
symbiosis encompassing mutualism through parasitismGO:00444031560.021
circadian behaviorGO:004851220.020
positive regulation of cellular amine metabolic processGO:003324070.020
regulation of cell migrationGO:00303342890.020
innate immune responseGO:00450871780.020
ubiquitin dependent protein catabolic processGO:00065112060.020
intracellular protein transportGO:00068862700.020
positive regulation of hydrolase activityGO:00513453310.020
regulation of peptidase activityGO:00525471800.020
gtp metabolic processGO:00460392390.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
mapk cascadeGO:00001652880.020
protein processingGO:00164852260.020
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.020
central nervous system developmentGO:00074171230.020
regulation of neuron differentiationGO:0045664700.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.020
secretion by cellGO:00329402260.020
taxisGO:00423301570.019
organ morphogenesisGO:00098871470.019
chemical homeostasisGO:00488783060.019
negative regulation of gene silencing by rnaGO:006096730.019
stem cell divisionGO:001714520.019
methylationGO:00322591060.019
cell adhesionGO:00071553250.019
vasculature developmentGO:00019441810.019
hippocampus developmentGO:002176610.019
regulation of intracellular protein transportGO:00331571230.019
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.019
circulatory system developmentGO:00723592620.019
positive regulation of programmed cell deathGO:00430682490.019
negative regulation of posttranscriptional gene silencingGO:006014930.019
neurotransmitter secretionGO:000726940.019
regulation of nucleotide catabolic processGO:00308112050.019
regulation of locomotionGO:00400123290.018
protein maturationGO:00516042330.018
gene silencingGO:0016458490.018
neuron projection morphogenesisGO:0048812500.018
maintenance of locationGO:00512351120.018
regulation of cell projection organizationGO:00313441070.018
peptidyl lysine acetylationGO:00183941010.018
gtp catabolic processGO:00061842370.018
motor neuron axon guidanceGO:000804520.018
angiogenesisGO:00015251470.018
negative regulation of proteolysisGO:00458611320.018
response to lipidGO:00339932060.018
endocytosisGO:00068971590.018
nerve developmentGO:002167540.018
regulation of transferase activityGO:00513383550.018
signal transduction by phosphorylationGO:00230142970.018
peptidyl lysine modificationGO:00182051440.018
regulation of purine nucleotide catabolic processGO:00331212050.018
response to nitrogen compoundGO:19016981840.018
regulation of meiotic cell cycleGO:005144540.018
regulation of cell motilityGO:20001452990.018
transmembrane transportGO:00550853990.018
regulation of small gtpase mediated signal transductionGO:00510561560.018
negative regulation of cellular amino acid metabolic processGO:004576320.017
cell morphogenesis involved in neuron differentiationGO:0048667440.017
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of neurogenesisGO:0050767820.017
inorganic ion transmembrane transportGO:00986602310.017
tripartite regional subdivisionGO:000735120.017
regulation of cytoplasmic transportGO:19036491490.017
negative regulation of phosphate metabolic processGO:00459362670.017
positive regulation of immune system processGO:00026842830.017
cell activationGO:00017752130.017
regulation of mapk cascadeGO:00434082620.017
protein alkylationGO:0008213740.017
secretionGO:00469032540.017
positive regulation of protein kinase activityGO:00458601900.017
negative regulation of growthGO:0045926970.017
negative regulation of organelle organizationGO:00106391260.017
atp metabolic processGO:00460341760.017
modification dependent protein catabolic processGO:00199412090.017
response to external biotic stimulusGO:00432072610.016
negative regulation of cell cycle processGO:00109481210.016
cellular chemical homeostasisGO:00550821800.016
meiosis iGO:000712740.016
associative learningGO:000830610.016
organelle localizationGO:0051640840.016
organelle fissionGO:00482851490.016
metal ion transportGO:00300012720.016
regulation of endopeptidase activityGO:00525481700.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
ribonucleoprotein complex subunit organizationGO:0071826810.016
regulation of vesicle mediated transportGO:00606271300.016
negative regulation of locomotionGO:00400131180.016
establishment or maintenance of cytoskeleton polarityGO:003095230.016
response to cytokineGO:00340972320.016
matingGO:000761810.016
cellular response to oxygen containing compoundGO:19017012760.016
nucleoside monophosphate metabolic processGO:00091231910.016
cell divisionGO:00513011680.015
regulation of wnt signaling pathwayGO:00301111230.015
small molecule biosynthetic processGO:00442831570.015
regulation of gtpase activityGO:00430871800.015
glycerolipid metabolic processGO:00464861070.015
negative regulation of mitotic cell cycleGO:00459301020.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
blood vessel developmentGO:00015681720.015
photoreceptor cell differentiationGO:004653020.015
regulation of protein kinase activityGO:00458592890.015
inorganic cation transmembrane transportGO:00986621940.015
positive regulation of growthGO:0045927580.015
histone acetylationGO:0016573930.015
regulation of cytoskeleton organizationGO:00514931770.015
stem cell differentiationGO:0048863930.015
positive regulation of cell growthGO:0030307480.015
dephosphorylationGO:00163112090.015
mrna splicing via spliceosomeGO:0000398890.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
modification of morphology or physiology of other organismGO:0035821430.015
cell cycle checkpointGO:00000751170.015
anterior posterior axis specification embryoGO:000859520.015
protein targetingGO:00066051870.015
cytokinesisGO:0000910960.015
ribonucleoprotein complex assemblyGO:0022618780.015
multi organism reproductive processGO:0044703540.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
epithelium migrationGO:00901321190.014
heart developmentGO:0007507950.014
ossificationGO:00015031210.014
negative regulation of cell differentiationGO:00455961710.014
neuroblast proliferationGO:000740540.014
cerebellum developmentGO:002154920.014
regulation of neurotransmitter secretionGO:004692830.014
actin filament organizationGO:00070151280.014
negative regulation of peptidase activityGO:0010466910.014
positive regulation of cellular component biogenesisGO:00440891580.014
ameboidal type cell migrationGO:00016671350.014
single organism membrane organizationGO:00448022680.014
neural tube formationGO:000184130.014
single organism reproductive processGO:0044702980.014
glial cell migrationGO:000834740.014
regulation of establishment of protein localizationGO:00702012420.014
response to woundingGO:00096111680.014
regulation of cell divisionGO:00513021160.014
negative regulation of viral processGO:0048525660.014
cellular component disassemblyGO:0022411920.014
microtubule based processGO:00070172100.014
cellular response to cytokine stimulusGO:00713451810.014
spinal cord developmentGO:002151040.014
cellular protein complex assemblyGO:00436231880.014
protein polyubiquitinationGO:00002091100.014
nuclear divisionGO:00002801280.014
sensory perceptionGO:00076001030.014
ion transmembrane transportGO:00342203380.014
monovalent inorganic cation transportGO:00156721280.014
positive regulation of nucleotide metabolic processGO:00459812300.014
golgi vesicle transportGO:0048193800.014
regulation of protein catabolic processGO:00421761550.014
cellular response to dna damage stimulusGO:00069743790.013
negative regulation of protein modification processGO:00314002000.013
muscle contractionGO:0006936730.013
regulation of cell morphogenesis involved in differentiationGO:0010769830.013
cation transmembrane transportGO:00986552380.013
negative regulation of cellular component movementGO:00512711060.013
phospholipid metabolic processGO:0006644990.013
positive regulation of kinase activityGO:00336742040.013
positive regulation of organelle organizationGO:00106381950.013
metencephalon developmentGO:002203720.013
negative regulation of cell migrationGO:00303361020.013
peptidyl tyrosine phosphorylationGO:00181081700.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
negative regulation of cell motilityGO:20001461040.013
morphogenesis of embryonic epitheliumGO:001633140.013
regulation of kinase activityGO:00435493140.013
carbohydrate metabolic processGO:00059752070.013
negative regulation of translationGO:0017148370.013
regulation of protein modification by small protein conjugation or removalGO:19033201070.013
response to organonitrogen compoundGO:00102431560.013
peptidyl tyrosine modificationGO:00182121700.013
nucleoside monophosphate catabolic processGO:00091251590.013
tissue regenerationGO:004224630.013
internal protein amino acid acetylationGO:00064751010.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
macromolecule methylationGO:0043414970.013
osteoblast differentiationGO:0001649920.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
regulation of neural precursor cell proliferationGO:200017740.013
tissue morphogenesisGO:0048729960.013
nucleocytoplasmic transportGO:00069131760.013
regulation of protein ubiquitinationGO:0031396950.013
embryonic epithelial tube formationGO:000183840.013
regulation of cysteine type endopeptidase activityGO:20001161270.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.012
leukocyte activationGO:00453211640.012
organonitrogen compound biosynthetic processGO:19015662000.012
regulation of mrna stabilityGO:0043488230.012
cellular response to organonitrogen compoundGO:00714171240.012
regulation of nucleocytoplasmic transportGO:0046822980.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of immune responseGO:00507762010.012
response to bacteriumGO:00096171440.012
dna conformation changeGO:00711031130.012
Human
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.012
positive regulation of locomotionGO:00400171860.012
chromosome segregationGO:00070591140.012
regulation of response to external stimulusGO:00321012220.012
neural crest cell developmentGO:001403230.012
atp catabolic processGO:00062001570.012
covalent chromatin modificationGO:00165692540.012
cell cycle g1 s phase transitionGO:0044843800.012
regulation of secretion by cellGO:19035301770.012
negative regulation of cell proliferationGO:00082852280.012
positive regulation of transferase activityGO:00513472270.012
carbohydrate derivative biosynthetic processGO:19011372070.012
regulation of homeostatic processGO:00328441210.012
single organism cell adhesionGO:00986021790.012
positive regulation of protein transportGO:00512221350.012
peripheral nervous system developmentGO:000742220.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
internal peptidyl lysine acetylationGO:0018393970.012
negative regulation of cysteine type endopeptidase activityGO:2000117480.012
developmental process involved in reproductionGO:0003006660.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
blastocyst developmentGO:000182430.012
positive regulation of proteolysisGO:00458621420.012
response to radiationGO:00093141510.012
head developmentGO:00603221080.012
negative regulation of phosphorus metabolic processGO:00105632670.012
regulation of secretionGO:00510461940.012
regulation of chromosome organizationGO:00330441030.012
response to organic cyclic compoundGO:00140702040.012
protein methylationGO:0006479740.012
endomembrane system organizationGO:00102561960.012
reactive oxygen species biosynthetic processGO:190340940.011
endosomal transportGO:00161971290.011
muscle system processGO:0003012810.011
regulation of rna stabilityGO:0043487230.011
negative regulation of cell cycle phase transitionGO:1901988890.011
regulation of neuron projection developmentGO:0010975570.011
long term memoryGO:000761620.011
inner ear morphogenesisGO:004247240.011
negative regulation of cell growthGO:0030308830.011
viral life cycleGO:00190581320.011
wound healingGO:00420601150.011
positive regulation of cell migrationGO:00303351720.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of cell developmentGO:0010720920.011
muscle structure developmentGO:0061061980.011
somitogenesisGO:000175620.011
response to axon injuryGO:004867810.011
regulation of viral transcriptionGO:0046782340.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
metal ion homeostasisGO:00550651690.011
reproductionGO:0000003630.011
positive regulation of synaptic transmissionGO:005080640.011
negative regulation of multi organism processGO:0043901920.011
monocarboxylic acid metabolic processGO:00327871850.011
regulation of ras gtpase activityGO:00323181280.011
response to growth factorGO:00708482050.011
sleepGO:003043120.011
myeloid cell differentiationGO:00300991170.011
reactive nitrogen species metabolic processGO:200105730.011
cell projection assemblyGO:00300311260.011
reactive oxygen species metabolic processGO:0072593750.011
protein localization to membraneGO:00726571600.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
syncytium formation by plasma membrane fusionGO:000076820.010
lipid localizationGO:00108761060.010
negative regulation of mitotic cell cycle phase transitionGO:1901991850.010
extrinsic apoptotic signaling pathwayGO:00971911190.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
regulation of reactive oxygen species metabolic processGO:2000377410.010
actin filament based movementGO:0030048170.010
lymphocyte activationGO:00466491330.010
sequestering of metal ionGO:0051238240.010
negative regulation of synaptic transmissionGO:005080520.010
cellular ion homeostasisGO:00068731680.010
nitrogen compound transportGO:00717051910.010
nuclear transportGO:00511691790.010
tissue migrationGO:00901301190.010
multi organism metabolic processGO:0044033410.010
positive regulation of mitotic cell cycleGO:0045931600.010
negative regulation of transportGO:00510511760.010
regulation of cellular protein catabolic processGO:1903362960.010
regulation of actin filament based processGO:00329701410.010
regulation of bindingGO:00510981110.010
negative regulation of catabolic processGO:00098951040.010
positive regulation of gtp catabolic processGO:00331261660.010
exocytosisGO:0006887710.010
synaptic transmissionGO:0007268610.010
cation homeostasisGO:00550801890.010
protein oligomerizationGO:00512591730.010

PURB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.025
sensory system diseaseDOID:00501552030.014
eye and adnexa diseaseDOID:14921500.014
nervous system diseaseDOID:8634310.014
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
disease of cellular proliferationDOID:145661740.013
disease of metabolismDOID:00146672950.012
central nervous system diseaseDOID:3311860.012
neurodegenerative diseaseDOID:12891020.012