Homo sapiens

40 known processes

PIR

pirin (iron-binding nuclear protein)

PIR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
testosterone biosynthetic processGO:006137020.421
retinoic acid biosynthetic processGO:000213820.318
oxidation reduction processGO:00551143960.283
regulation of testosterone biosynthetic processGO:200022420.211
monocarboxylic acid metabolic processGO:00327871850.110
small molecule biosynthetic processGO:00442831570.104
cellular amino acid metabolic processGO:00065201160.095
androgen biosynthetic processGO:000670230.084
lipid metabolic processGO:00066293810.084
cellular ketone metabolic processGO:0042180800.064
lipid biosynthetic processGO:00086101770.062
reactive oxygen species metabolic processGO:0072593750.062
regulation of cellular ketone metabolic processGO:0010565500.060
response to oxidative stressGO:00069791210.057
organic acid biosynthetic processGO:0016053970.054
response to oxygen containing compoundGO:19017003690.054
cellular amine metabolic processGO:0044106410.053
determination of adult lifespanGO:000834020.052
cytoplasmic transportGO:00164823790.049
multicellular organismal agingGO:001025930.049
positive regulation of apoptotic processGO:00430652460.045
positive regulation of programmed cell deathGO:00430682490.043
response to hormoneGO:00097251750.043
primary alcohol metabolic processGO:0034308170.042
cellular lipid metabolic processGO:00442553030.042
regulation of cellular amino acid metabolic processGO:000652160.042
regulation of cellular amine metabolic processGO:0033238110.041
organic hydroxy compound metabolic processGO:19016151470.041
positive regulation of cell deathGO:00109422630.040
protein oligomerizationGO:00512591730.040
cellular response to oxygen containing compoundGO:19017012760.040
single organism cellular localizationGO:19025803320.040
post embryonic developmentGO:000979120.038
carboxylic acid biosynthetic processGO:0046394970.038
cellular response to oxidative stressGO:0034599850.038
positive regulation of cellular amine metabolic processGO:003324070.037
ras protein signal transductionGO:0007265730.036
small gtpase mediated signal transductionGO:0007264780.036
amine metabolic processGO:0009308440.036
ketone catabolic processGO:004218230.035
negative regulation of catalytic activityGO:00430863350.035
system processGO:00030083490.034
diterpenoid biosynthetic processGO:001610220.034
locomotory behaviorGO:000762610.034
positive regulation of cellular amino acid metabolic processGO:004576430.033
response to organic cyclic compoundGO:00140702040.033
cofactor metabolic processGO:0051186870.033
nucleoside phosphate catabolic processGO:19012924120.033
apoptotic signaling pathwayGO:00971902680.033
protein localization to organelleGO:00333652800.032
organophosphate catabolic processGO:00464344300.032
monocarboxylic acid biosynthetic processGO:0072330670.031
immune responseGO:00069553070.031
negative regulation of cellular protein metabolic processGO:00322693530.031
female gamete generationGO:000729220.031
glycosyl compound catabolic processGO:19016584130.030
negative regulation of protein metabolic processGO:00512483910.029
purine nucleotide catabolic processGO:00061954050.029
response to external biotic stimulusGO:00432072610.029
ribonucleotide catabolic processGO:00092614050.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
organonitrogen compound biosynthetic processGO:19015662000.028
epithelium developmentGO:00604292270.028
regulation of proteolysisGO:00301622930.028
nucleoside triphosphate metabolic processGO:00091414220.028
response to lipidGO:00339932060.028
purine ribonucleoside metabolic processGO:00461284370.028
intracellular protein transportGO:00068862700.028
sulfur compound metabolic processGO:00067901010.028
segmentationGO:003528240.028
purine containing compound catabolic processGO:00725234110.027
terpenoid biosynthetic processGO:001611420.027
regulation of cytokine productionGO:00018172320.027
alcohol metabolic processGO:00060661140.027
membrane organizationGO:00610242920.027
rho protein signal transductionGO:0007266260.027
oogenesisGO:004847720.027
fatty acid metabolic processGO:00066311150.027
unsaturated fatty acid metabolic processGO:0033559370.026
innate immune responseGO:00450871780.026
cellular response to oxygen radicalGO:007145060.026
dicarboxylic acid metabolic processGO:0043648290.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
protein homooligomerizationGO:00512601000.026
nucleoside triphosphate catabolic processGO:00091433940.026
ribonucleoside triphosphate catabolic processGO:00092033910.025
protein targetingGO:00066051870.025
cellular homeostasisGO:00197251960.025
ribonucleoside catabolic processGO:00424544060.025
response to reactive oxygen speciesGO:0000302610.025
nervous system developmentGO:00073992930.025
limbic system developmentGO:002176130.025
nucleotide catabolic processGO:00091664080.025
negative regulation of phosphate metabolic processGO:00459362670.024
single organism membrane organizationGO:00448022680.024
negative regulation of cell deathGO:00605483450.024
purine nucleoside catabolic processGO:00061523980.024
cellular macromolecular complex assemblyGO:00346223240.024
response to other organismGO:00517072610.024
cellular response to endogenous stimulusGO:00714953360.023
neuromuscular junction developmentGO:000752830.023
positive regulation of hydrolase activityGO:00513453310.023
cellular macromolecule catabolic processGO:00442653800.023
purine ribonucleotide catabolic processGO:00091544040.023
negative regulation of phosphorus metabolic processGO:00105632670.023
positive regulation of cell proliferationGO:00082843010.023
regulation of protein kinase activityGO:00458592890.023
nucleoside catabolic processGO:00091644080.023
gtp metabolic processGO:00460392390.023
negative regulation of retinoic acid biosynthetic processGO:190005310.023
adult locomotory behaviorGO:000834410.023
purine ribonucleoside catabolic processGO:00461303980.023
regulation of protein localizationGO:00328802960.023
ion homeostasisGO:00508012300.023
vesicle mediated transportGO:00161923710.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
defense responseGO:00069523150.022
positive regulation of phosphorylationGO:00423273940.022
regulation of cell differentiationGO:00455953930.022
regulation of transferase activityGO:00513383550.022
positive regulation of cellular component organizationGO:00511303760.022
positive regulation of cellular catabolic processGO:00313312840.022
cation transportGO:00068123310.022
regulation of kinase activityGO:00435493140.022
establishment of protein localization to organelleGO:00725941720.022
positive regulation of transportGO:00510503360.022
carbohydrate metabolic processGO:00059752070.022
regulation of cell cycleGO:00517263930.022
reactive oxygen species biosynthetic processGO:190340940.022
regenerationGO:003109940.022
positive regulation of catabolic processGO:00098963100.022
response to inorganic substanceGO:00100351270.021
nitrogen compound transportGO:00717051910.021
protein catabolic processGO:00301633250.021
cytokine productionGO:00018162470.021
mitotic cell cycleGO:00002783260.021
regulation of reactive oxygen species metabolic processGO:2000377410.021
steroid metabolic processGO:0008202940.021
guanosine containing compound metabolic processGO:19010682440.021
response to biotic stimulusGO:00096072760.021
regulation of cellular response to stressGO:00801352440.021
response to abiotic stimulusGO:00096283360.021
regulation of establishment of protein localizationGO:00702012420.021
hindbrain developmentGO:003090230.020
cellular protein complex assemblyGO:00436231880.020
fatty acid derivative metabolic processGO:1901568350.020
response to extracellular stimulusGO:0009991850.020
cell morphogenesisGO:00009022960.020
mitochondrion organizationGO:00070051560.020
diterpenoid metabolic processGO:0016101200.020
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.020
regulation of anatomical structure morphogenesisGO:00226032860.020
regulation of intracellular transportGO:00323861950.020
glutathione metabolic processGO:0006749200.020
guanosine containing compound catabolic processGO:19010692390.019
alpha amino acid metabolic processGO:1901605720.019
negative regulation of apoptotic processGO:00430663160.019
anterior posterior axis specificationGO:000994820.019
blastoderm segmentationGO:000735020.019
memoryGO:000761330.019
cell type specific apoptotic processGO:00972851250.019
cellular protein catabolic processGO:00442572610.019
negative regulation of cellular component organizationGO:00511292350.019
mapk cascadeGO:00001652880.019
regulation of membrane potentialGO:0042391950.019
lipid catabolic processGO:0016042840.019
protein processingGO:00164852260.019
dephosphorylationGO:00163112090.019
biological adhesionGO:00226103310.019
regulation of nucleotide metabolic processGO:00061402690.019
oocyte developmentGO:004859910.019
morphogenesis of embryonic epitheliumGO:001633140.019
small molecule catabolic processGO:0044282920.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of nucleotide catabolic processGO:00308112050.018
gtp catabolic processGO:00061842370.018
regulation of protein transportGO:00512232130.018
regulation of purine nucleotide metabolic processGO:19005422640.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
cellular component morphogenesisGO:00329893140.018
protein modification by small protein conjugationGO:00324463420.018
protein maturationGO:00516042330.018
cellular modified amino acid metabolic processGO:0006575640.018
protein ubiquitinationGO:00165673140.018
cellular response to dna damage stimulusGO:00069743790.018
chemical homeostasisGO:00488783060.018
negative regulation of hydrolase activityGO:00513461820.018
nuclear importGO:00511701060.018
positive regulation of nucleotide metabolic processGO:00459812300.018
spermatid differentiationGO:004851540.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
regulation of cellular component biogenesisGO:00440872810.018
signal transduction by phosphorylationGO:00230142970.017
superoxide metabolic processGO:0006801200.017
carbohydrate derivative biosynthetic processGO:19011372070.017
cellular response to prostaglandin stimulusGO:007137940.017
icosanoid metabolic processGO:0006690350.017
positive regulation of synaptic transmissionGO:005080640.017
embryonic epithelial tube formationGO:000183840.017
cardiac muscle cell contractionGO:008600340.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
cellular amide metabolic processGO:0043603690.017
epithelial cell differentiationGO:00308551410.017
secretionGO:00469032540.017
positive regulation of reactive oxygen species metabolic processGO:2000379240.017
regulation of cellular component movementGO:00512703340.017
regulation of purine nucleotide catabolic processGO:00331212050.017
nonribosomal peptide biosynthetic processGO:001918440.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
regulation of nucleoside metabolic processGO:00091182090.017
actin filament based processGO:00300292240.017
cell projection organizationGO:00300302520.017
peripheral nervous system developmentGO:000742220.017
reactive nitrogen species metabolic processGO:200105730.017
motor neuron axon guidanceGO:000804520.016
sterol catabolic processGO:001612730.016
ubiquitin dependent protein catabolic processGO:00065112060.016
positive regulation of protein phosphorylationGO:00019343130.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
posttranscriptional regulation of gene expressionGO:00106082130.016
inner ear morphogenesisGO:004247240.016
cell developmentGO:00484683280.016
transmembrane transportGO:00550853990.016
regulation of response to external stimulusGO:00321012220.016
organic hydroxy compound biosynthetic processGO:1901617710.016
negative regulation of protein modification processGO:00314002000.016
cellular amino acid biosynthetic processGO:0008652300.016
glutathione biosynthetic processGO:000675040.016
regulation of apoptotic signaling pathwayGO:20012331750.016
metal ion transportGO:00300012720.016
single organism nuclear importGO:19025931040.016
cell fate determinationGO:000170930.016
cardiovascular system developmentGO:00723582620.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
cell adhesionGO:00071553250.016
chromatin modificationGO:00165682980.015
positive regulation of organelle organizationGO:00106381950.015
negative regulation of multicellular organismal processGO:00512413170.015
rhythmic behaviorGO:000762220.015
regulation of hormone levelsGO:00108171250.015
regulation of secretionGO:00510461940.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
actin mediated cell contractionGO:0070252120.015
regulation of gtpase activityGO:00430871800.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
regulation of protein catabolic processGO:00421761550.015
sesquiterpenoid metabolic processGO:000671430.015
response to steroid hormoneGO:0048545800.015
spinal cord developmentGO:002151040.015
regulation of endopeptidase activityGO:00525481700.015
cellular response to external stimulusGO:00714961110.015
positive regulation of developmental processGO:00510943140.015
regulation of secretion by cellGO:19035301770.015
rna processingGO:00063962550.015
histone modificationGO:00165702510.015
regulation of cell cycle processGO:00105642660.015
response to drugGO:0042493810.015
response to nitrogen compoundGO:19016981840.015
negative regulation of programmed cell deathGO:00430693210.015
organ formationGO:004864530.015
response to axon injuryGO:004867810.015
regulation of ras protein signal transductionGO:00465781550.015
protein import into nucleusGO:00066061040.015
anterior posterior axis specification embryoGO:000859520.015
hippocampus developmentGO:002176610.015
atp metabolic processGO:00460341760.015
mitotic cell cycle processGO:19030472860.015
regulation of gtp catabolic processGO:00331241800.015
endomembrane system organizationGO:00102561960.015
regulation of locomotionGO:00400123290.015
hormone metabolic processGO:0042445610.015
protein targeting to nucleusGO:00447441040.014
positive regulation of cell differentiationGO:00455972110.014
response to nutrient levelsGO:0031667810.014
nuclear transportGO:00511691790.014
maintenance of locationGO:00512351120.014
neurotransmitter secretionGO:000726940.014
oocyte differentiationGO:000999420.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
nucleoside monophosphate metabolic processGO:00091231910.014
growthGO:00400072020.014
positive regulation of cytokine productionGO:00018191670.014
secretion by cellGO:00329402260.014
cellular response to hormone stimulusGO:00328701250.014
primary alcohol catabolic processGO:003431030.014
positive regulation of nucleoside metabolic processGO:00459791860.014
associative learningGO:000830610.014
central nervous system developmentGO:00074171230.014
regulation of synaptic plasticityGO:004816730.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of immune system processGO:00026842830.014
negative regulation of phosphorylationGO:00423261740.014
modification dependent protein catabolic processGO:00199412090.014
tripartite regional subdivisionGO:000735120.014
negative regulation of cell proliferationGO:00082852280.014
ion transmembrane transportGO:00342203380.014
regulation of growthGO:00400081650.014
cellular response to organic cyclic compoundGO:00714071270.014
negative regulation of intracellular signal transductionGO:19025321830.014
regulation of protein maturationGO:19033171500.014
positive regulation of nucleotide catabolic processGO:00308131850.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
neurological system processGO:00508771630.014
circulatory system processGO:00030131130.014
compound eye developmentGO:004874910.014
photoreceptor cell differentiationGO:004653020.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
steroid biosynthetic processGO:0006694460.013
regulation of mapk cascadeGO:00434082620.013
regulation of cell motilityGO:20001452990.013
single organism carbohydrate metabolic processGO:00447231930.013
circadian behaviorGO:004851220.013
inorganic ion transmembrane transportGO:00986602310.013
endosomal transportGO:00161971290.013
tissue regenerationGO:004224630.013
protein importGO:00170381300.013
morphogenesis of a polarized epitheliumGO:000173830.013
regulation of protein processingGO:00706131500.013
response to bacteriumGO:00096171440.013
metencephalon developmentGO:002203720.013
negative regulation of protein maturationGO:19033181420.013
metal ion homeostasisGO:00550651690.013
glycerolipid metabolic processGO:00464861070.013
regulation of multi organism processGO:00439001570.013
negative regulation of protein processingGO:00109551420.013
rna interferenceGO:001624640.013
head developmentGO:00603221080.013
microtubule based processGO:00070172100.013
interspecies interaction between organismsGO:00444191560.013
cation homeostasisGO:00550801890.013
specification of organ identityGO:001009230.013
spermatid developmentGO:000728640.013
negative regulation of proteolysisGO:00458611320.013
immune system developmentGO:00025201950.013
cellular response to lipidGO:00713961270.013
positive regulation of kinase activityGO:00336742040.013
protein localization to membraneGO:00726571600.013
positive regulation of transferase activityGO:00513472270.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of cytoplasmic transportGO:19036491490.013
prostanoid metabolic processGO:0006692170.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
nucleocytoplasmic transportGO:00069131760.013
organic anion transportGO:00157111030.013
heart formationGO:006091420.013
negative regulation of developmental processGO:00510932470.013
multi organism cellular processGO:00447641560.013
regulation of lipid metabolic processGO:0019216960.013
organophosphate biosynthetic processGO:00904071630.013
positive regulation of gtp catabolic processGO:00331261660.013
organelle assemblyGO:00709251760.013
alcohol biosynthetic processGO:0046165520.013
neuron fate commitmentGO:004866320.013
response to metal ionGO:0010038840.013
salivary gland morphogenesisGO:000743540.013
glycoprotein metabolic processGO:00091001100.012
startle responseGO:000196430.012
inorganic cation transmembrane transportGO:00986621940.012
actin filament based movementGO:0030048170.012
cell projection assemblyGO:00300311260.012
g protein coupled receptor signaling pathwayGO:00071862070.012
cell growthGO:00160491600.012
wnt signaling pathwayGO:00160551560.012
syncytium formation by plasma membrane fusionGO:000076820.012
establishment of planar polarityGO:000173630.012
microtubule cytoskeleton organizationGO:00002261760.012
regulation of ras gtpase activityGO:00323181280.012
hormone catabolic processGO:004244740.012
cation transmembrane transportGO:00986552380.012
positive regulation of proteolysisGO:00458621420.012
regulation of immune responseGO:00507762010.012
protein localization to nucleusGO:00345041360.012
establishment of protein localization to membraneGO:00901501210.012
regulation of lipid biosynthetic processGO:0046890470.012
peptide metabolic processGO:0006518510.012
cell divisionGO:00513011680.012
cellular lipid catabolic processGO:0044242650.012
tube closureGO:006060630.012
negative regulation of protein phosphorylationGO:00019331400.012
phospholipid metabolic processGO:0006644990.012
sequestering of metal ionGO:0051238240.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
negative regulation of cell cycleGO:00457861930.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
response to fungusGO:000962040.012
thymus developmentGO:004853830.012
plasma membrane organizationGO:00070091150.012
neural tube formationGO:000184130.012
primary neural tube formationGO:001402030.012
regulation of vesicle mediated transportGO:00606271300.012
dna repairGO:00062811980.012
sequestering of calcium ionGO:0051208170.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
epithelial tube branching involved in lung morphogenesisGO:006044140.012
negative regulation of transferase activityGO:00513481240.012
sensory perception of painGO:001923340.012
regulation of cytoskeleton organizationGO:00514931770.012
brain developmentGO:0007420970.012
circulatory system developmentGO:00723592620.011
divalent inorganic cation transportGO:00725111580.011
response to radiationGO:00093141510.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of homeostatic processGO:00328441210.011
apoptotic mitochondrial changesGO:0008637570.011
neuroblast proliferationGO:000740540.011
proteasomal protein catabolic processGO:00104981760.011
cellular cation homeostasisGO:00300031630.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
sulfur compound biosynthetic processGO:0044272380.011
regulation of mitotic cell cycleGO:00073461890.011
cell cycle phase transitionGO:00447701730.011
regulation of intracellular protein transportGO:00331571230.011
regulation of neuron deathGO:1901214560.011
response to cytokineGO:00340972320.011
regulation of meiotic cell cycleGO:005144540.011
mrna metabolic processGO:00160711750.011
single organism cell adhesionGO:00986021790.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
intracellular receptor signaling pathwayGO:00305221040.011
nerve developmentGO:002167540.011
anion transportGO:00068201610.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
developmental programmed cell deathGO:001062330.011
glial cell migrationGO:000834740.011
positive regulation of secretionGO:00510471160.011
pituitary gland developmentGO:002198320.011
regulation of protein complex assemblyGO:00432541470.011
protein acylationGO:00435431380.011
peptidyl lysine modificationGO:00182051440.011
cellular chemical homeostasisGO:00550821800.011
regulation of glial cell differentiationGO:004568530.011
cerebellum developmentGO:002154920.011
neurogenesisGO:00220081690.011
regulation of cell growthGO:00015581350.011
regulation of peptidase activityGO:00525471800.011
visual behaviorGO:000763220.011
neural tube closureGO:000184330.011
establishment of tissue polarityGO:000716430.011
somitogenesisGO:000175620.011
positive regulation of protein transportGO:00512221350.011
blood circulationGO:00080151130.011
epidermis morphogenesisGO:004873030.011
regulation of cell migrationGO:00303342890.011
cell activationGO:00017752130.011
covalent chromatin modificationGO:00165692540.011
negative regulation of peptidase activityGO:0010466910.011
myoblast fusionGO:000752010.011
actin cytoskeleton organizationGO:00300362070.011
sensory perception of smellGO:000760820.011
positive regulation of gtpase activityGO:00435471660.011
negative regulation of organelle organizationGO:00106391260.011
positive regulation of neural precursor cell proliferationGO:200017920.011
embryonic placenta developmentGO:000189210.011
i kappab kinase nf kappab signalingGO:00072491660.011
isoprenoid metabolic processGO:0006720390.011
lens development in camera type eyeGO:000208820.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
cellular response to jasmonic acid stimulusGO:007139540.011
meiosis iGO:000712740.011
regulation of defense responseGO:00313471540.011
regulation of wnt signaling pathwayGO:00301111230.011
fatty acid biosynthetic processGO:0006633460.011
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.011
blood vessel morphogenesisGO:00485141620.010
forelimb morphogenesisGO:003513640.010

PIR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.036
nervous system diseaseDOID:8634310.029
central nervous system diseaseDOID:3311860.029
inherited metabolic disorderDOID:6552420.026
musculoskeletal system diseaseDOID:172230.025
cancerDOID:1621670.024
disease of cellular proliferationDOID:145661740.024
sensory system diseaseDOID:00501552030.021
organ system cancerDOID:00506861640.021
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
neurodegenerative diseaseDOID:12891020.016
immune system diseaseDOID:29141550.015
muscle tissue diseaseDOID:661130.015
muscular diseaseDOID:00800001140.015
myopathyDOID:4231040.015
bone diseaseDOID:0080001880.015
connective tissue diseaseDOID:651090.015
amino acid metabolic disorderDOID:9252500.014
cardiovascular system diseaseDOID:12871060.014
retinal diseaseDOID:56791180.013
hematopoietic system diseaseDOID:741000.012
brain diseaseDOID:936730.011