Homo sapiens

27 known processes

SIRT3

sirtuin 3

(Aliases: SIR2L3)

SIRT3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cardiac muscle cell apoptotic processGO:001066720.495
lipid metabolic processGO:00066293810.216
oxidation reduction processGO:00551143960.210
regulation of cardiac muscle cell apoptotic processGO:001066530.201
cellular amino acid metabolic processGO:00065201160.190
negative regulation of apoptotic processGO:00430663160.188
negative regulation of cell deathGO:00605483450.173
negative regulation of programmed cell deathGO:00430693210.166
peptidyl lysine modificationGO:00182051440.158
negative regulation of striated muscle cell apoptotic processGO:001066420.144
transmembrane transportGO:00550853990.142
protein deacylationGO:0035601390.121
response to oxygen containing compoundGO:19017003690.121
protein deacetylationGO:0006476380.116
purine nucleotide catabolic processGO:00061954050.108
monocarboxylic acid metabolic processGO:00327871850.104
purine nucleoside catabolic processGO:00061523980.092
striated muscle cell apoptotic processGO:001065830.082
regulation of cellular ketone metabolic processGO:0010565500.081
single organism cellular localizationGO:19025803320.081
small molecule biosynthetic processGO:00442831570.080
cellular lipid metabolic processGO:00442553030.079
mitochondrion organizationGO:00070051560.079
cardiac muscle cell apoptotic processGO:001065930.078
organonitrogen compound biosynthetic processGO:19015662000.076
secretionGO:00469032540.074
Rat
cellular response to oxygen containing compoundGO:19017012760.071
single organism membrane organizationGO:00448022680.071
nucleoside triphosphate metabolic processGO:00091414220.070
membrane organizationGO:00610242920.068
organophosphate biosynthetic processGO:00904071630.066
carbohydrate derivative biosynthetic processGO:19011372070.063
protein localization to membraneGO:00726571600.062
purine ribonucleotide catabolic processGO:00091544040.062
cation transportGO:00068123310.062
ribonucleotide catabolic processGO:00092614050.061
regulation of meiotic cell cycleGO:005144540.060
negative regulation of cell proliferationGO:00082852280.058
regulation of reactive oxygen species metabolic processGO:2000377410.058
Rat
atp metabolic processGO:00460341760.057
cytoplasmic transportGO:00164823790.056
reactive oxygen species metabolic processGO:0072593750.056
Rat
negative regulation of protein metabolic processGO:00512483910.054
Mouse
ribonucleoside triphosphate catabolic processGO:00092033910.053
response to abiotic stimulusGO:00096283360.053
cation transmembrane transportGO:00986552380.053
nucleotide catabolic processGO:00091664080.052
post embryonic developmentGO:000979120.052
organophosphate catabolic processGO:00464344300.051
cell type specific apoptotic processGO:00972851250.051
regulation of cell cycleGO:00517263930.051
carboxylic acid biosynthetic processGO:0046394970.051
regulation of cellular component biogenesisGO:00440872810.050
purine ribonucleoside catabolic processGO:00461303980.050
macromolecule deacylationGO:0098732410.050
inorganic cation transmembrane transportGO:00986621940.050
glycosyl compound catabolic processGO:19016584130.049
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
cellular response to hormone stimulusGO:00328701250.049
nucleoside triphosphate catabolic processGO:00091433940.049
ribonucleoside triphosphate metabolic processGO:00091994120.048
nucleoside phosphate catabolic processGO:19012924120.048
cellular response to dna damage stimulusGO:00069743790.048
determination of adult lifespanGO:000834020.046
purine nucleoside triphosphate metabolic processGO:00091444120.045
ion transmembrane transportGO:00342203380.044
cellular response to endogenous stimulusGO:00714953360.044
purine containing compound catabolic processGO:00725234110.044
ribonucleoside catabolic processGO:00424544060.043
cell cell signalingGO:00072671550.043
Rat
inorganic ion transmembrane transportGO:00986602310.043
intracellular protein transportGO:00068862700.042
regulation of mitochondrion organizationGO:0010821540.042
cell projection organizationGO:00300302520.041
response to nitrogen compoundGO:19016981840.041
system processGO:00030083490.040
apoptotic signaling pathwayGO:00971902680.039
atp catabolic processGO:00062001570.039
ribonucleoside monophosphate metabolic processGO:00091611870.039
regulation of cellular amino acid metabolic processGO:000652160.037
regulation of lipid metabolic processGO:0019216960.037
protein localization to organelleGO:00333652800.037
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
positive regulation of protein phosphorylationGO:00019343130.036
negative regulation of cellular component organizationGO:00511292350.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
regulation of transferase activityGO:00513383550.036
female gamete generationGO:000729220.036
multicellular organismal agingGO:001025930.036
positive regulation of apoptotic processGO:00430652460.035
lipid biosynthetic processGO:00086101770.035
carbohydrate metabolic processGO:00059752070.035
regulation of apoptotic signaling pathwayGO:20012331750.035
fatty acid metabolic processGO:00066311150.035
nucleoside catabolic processGO:00091644080.035
response to organonitrogen compoundGO:00102431560.035
establishment of protein localization to membraneGO:00901501210.035
negative regulation of cellular protein metabolic processGO:00322693530.034
Mouse
protein modification by small protein conjugationGO:00324463420.034
endomembrane system organizationGO:00102561960.034
protein processingGO:00164852260.034
negative regulation of reactive oxygen species metabolic processGO:2000378110.033
Rat
cofactor metabolic processGO:0051186870.033
spermatid developmentGO:000728640.033
response to organic cyclic compoundGO:00140702040.033
amine metabolic processGO:0009308440.033
mitotic cell cycleGO:00002783260.033
protein maturationGO:00516042330.033
single organism carbohydrate metabolic processGO:00447231930.032
cellular metal ion homeostasisGO:00068751460.032
nucleoside monophosphate metabolic processGO:00091231910.031
establishment of protein localization to organelleGO:00725941720.031
growthGO:00400072020.031
cellular protein catabolic processGO:00442572610.031
regulation of cellular amine metabolic processGO:0033238110.030
positive regulation of cell deathGO:00109422630.030
positive regulation of meiotic cell cycleGO:005144620.030
memoryGO:000761330.030
protein ubiquitinationGO:00165673140.029
positive regulation of nucleotide metabolic processGO:00459812300.029
cellular chemical homeostasisGO:00550821800.029
purine ribonucleoside metabolic processGO:00461284370.028
sulfur compound metabolic processGO:00067901010.028
neurotransmitter secretionGO:000726940.028
negative regulation of catalytic activityGO:00430863350.028
cellular response to organonitrogen compoundGO:00714171240.028
response to lipidGO:00339932060.028
regulation of mitotic cell cycleGO:00073461890.028
rab protein signal transductionGO:003248240.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
regulation of protein localizationGO:00328802960.027
nervous system developmentGO:00073992930.027
regulation of cell cycle processGO:00105642660.027
organic acid biosynthetic processGO:0016053970.027
guanosine containing compound metabolic processGO:19010682440.027
protein targetingGO:00066051870.026
positive regulation of cell differentiationGO:00455972110.026
ribonucleoside monophosphate catabolic processGO:00091581580.026
oogenesisGO:004847720.025
regulation of hormone levelsGO:00108171250.025
Rat
purine ribonucleoside monophosphate catabolic processGO:00091691580.025
small molecule catabolic processGO:0044282920.025
negative regulation of protein maturationGO:19033181420.025
response to hormoneGO:00097251750.025
regulation of purine nucleotide metabolic processGO:19005422640.025
nucleoside monophosphate catabolic processGO:00091251590.025
regulation of proteolysisGO:00301622930.024
negative regulation of cell cycleGO:00457861930.024
glycerolipid metabolic processGO:00464861070.024
negative regulation of hydrolase activityGO:00513461820.024
secretion by cellGO:00329402260.024
Rat
protein oligomerizationGO:00512591730.024
positive regulation of cell cycleGO:00457871400.024
positive regulation of hydrolase activityGO:00513453310.024
ras protein signal transductionGO:0007265730.023
cellular macromolecule catabolic processGO:00442653800.023
blastoderm segmentationGO:000735020.023
divalent inorganic cation homeostasisGO:00725071360.023
ion homeostasisGO:00508012300.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
purine nucleoside monophosphate metabolic processGO:00091261860.023
regulation of lipid biosynthetic processGO:0046890470.023
locomotory behaviorGO:000762610.023
response to cytokineGO:00340972320.023
dephosphorylationGO:00163112090.023
cellular component morphogenesisGO:00329893140.022
single organism reproductive processGO:0044702980.022
protein catabolic processGO:00301633250.022
regulation of protein maturationGO:19033171500.022
response to extracellular stimulusGO:0009991850.022
regulation of cell growthGO:00015581350.022
regulation of protein processingGO:00706131500.022
positive regulation of nucleoside metabolic processGO:00459791860.022
regulation of intracellular transportGO:00323861950.022
cellular response to nitrogen compoundGO:19016991440.021
cell developmentGO:00484683280.021
positive regulation of cellular amine metabolic processGO:003324070.021
reproductive processGO:00224141060.021
response to salt stressGO:000965130.021
carboxylic acid catabolic processGO:0046395710.021
coenzyme metabolic processGO:0006732650.021
cellular homeostasisGO:00197251960.021
spermatid differentiationGO:004851540.021
negative regulation of synaptic transmissionGO:005080520.021
maintenance of locationGO:00512351120.021
negative regulation of organelle organizationGO:00106391260.020
neuromuscular junction developmentGO:000752830.020
small gtpase mediated signal transductionGO:0007264780.020
purine containing compound biosynthetic processGO:0072522880.020
cellular ketone metabolic processGO:0042180800.020
alpha amino acid metabolic processGO:1901605720.020
nucleoside phosphate biosynthetic processGO:19012931090.020
purine nucleotide biosynthetic processGO:0006164840.019
regulation of secretion by cellGO:19035301770.019
Rat
positive regulation of programmed cell deathGO:00430682490.019
calcium ion transmembrane transportGO:0070588760.019
guanosine containing compound catabolic processGO:19010692390.019
response to hyperoxiaGO:005509340.019
segmentationGO:003528240.019
protein homooligomerizationGO:00512601000.019
vesicle mediated transportGO:00161923710.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
cell morphogenesisGO:00009022960.019
positive regulation of cellular component organizationGO:00511303760.019
negative regulation of protein processingGO:00109551420.018
regenerationGO:003109940.018
nitrogen compound transportGO:00717051910.018
Rat
protein acetylationGO:00064731160.018
Mouse
purine ribonucleotide biosynthetic processGO:0009152790.018
cell projection morphogenesisGO:00488581290.018
regulation of cell differentiationGO:00455953930.018
establishment of protein localization to mitochondrionGO:0072655220.018
positive regulation of transferase activityGO:00513472270.018
response to acid chemicalGO:0001101660.018
ribonucleotide biosynthetic processGO:0009260810.018
regulation of establishment of protein localizationGO:00702012420.018
positive regulation of cellular catabolic processGO:00313312840.018
endosomal transportGO:00161971290.018
cation homeostasisGO:00550801890.018
regulation of ion transmembrane transporter activityGO:0032412720.018
response to steroid hormoneGO:0048545800.018
cellular ion homeostasisGO:00068731680.017
regulation of peptidase activityGO:00525471800.017
morphogenesis of embryonic epitheliumGO:001633140.017
matingGO:000761810.017
regulation of kinase activityGO:00435493140.017
cellular amine metabolic processGO:0044106410.017
chemical homeostasisGO:00488783060.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
regulation of ion transportGO:00432691890.017
regulation of growthGO:00400081650.017
wnt signaling pathwayGO:00160551560.017
negative regulation of intracellular signal transductionGO:19025321830.017
Rat
muscle system processGO:0003012810.017
nucleotide biosynthetic processGO:00091651090.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
mitotic cell cycle processGO:19030472860.017
regulation of cysteine type endopeptidase activityGO:20001161270.017
regulation of purine nucleotide catabolic processGO:00331212050.017
regulation of homeostatic processGO:00328441210.017
enzyme linked receptor protein signaling pathwayGO:00071673030.016
monocarboxylic acid biosynthetic processGO:0072330670.016
metal ion transportGO:00300012720.016
cellular amino acid biosynthetic processGO:0008652300.016
positive regulation of lipid biosynthetic processGO:0046889220.016
positive regulation of rab gtpase activityGO:0032851390.016
regulation of nucleotide metabolic processGO:00061402690.016
negative regulation of phosphorus metabolic processGO:00105632670.016
Rat
regulation of nucleotide catabolic processGO:00308112050.016
calcium ion homeostasisGO:00550741220.016
alcohol metabolic processGO:00060661140.016
oocyte developmentGO:004859910.016
ribose phosphate biosynthetic processGO:0046390820.016
cell growthGO:00160491600.016
phospholipid metabolic processGO:0006644990.016
organelle fissionGO:00482851490.016
positive regulation of phosphorylationGO:00423273940.016
signal releaseGO:0023061700.016
Rat
plasma membrane organizationGO:00070091150.016
anion transportGO:00068201610.016
lipid localizationGO:00108761060.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
chromatin organizationGO:00063253510.016
Yeast Mouse
glycoprotein biosynthetic processGO:0009101910.016
regulation of ras gtpase activityGO:00323181280.015
protein acylationGO:00435431380.015
Mouse
regulation of synaptic plasticityGO:004816730.015
negative regulation of apoptotic signaling pathwayGO:2001234970.015
negative regulation of cellular amine metabolic processGO:003323930.015
proteasomal protein catabolic processGO:00104981760.015
lipid modificationGO:0030258840.015
response to increased oxygen levelsGO:003629640.015
glycoprotein metabolic processGO:00091001100.015
cell projection assemblyGO:00300311260.015
monovalent inorganic cation transportGO:00156721280.015
regulation of ras protein signal transductionGO:00465781550.015
protein importGO:00170381300.015
regulation of phosphatase activityGO:0010921810.015
organic acid catabolic processGO:0016054710.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
positive regulation of ras gtpase activityGO:00323201170.015
hormone secretionGO:0046879650.015
Rat
regulation of protein kinase activityGO:00458592890.014
negative regulation of multicellular organismal processGO:00512413170.014
protein localization to plasma membraneGO:0072659930.014
glycerophospholipid metabolic processGO:0006650840.014
positive regulation of immune system processGO:00026842830.014
negative regulation of transportGO:00510511760.014
associative learningGO:000830610.014
cellular response to lipidGO:00713961270.014
epithelial cell proliferationGO:00506731280.014
mitochondrial transportGO:0006839600.014
meiotic chromosome segregationGO:004513240.014
actin filament based processGO:00300292240.014
organic anion transportGO:00157111030.014
cellular response to acid chemicalGO:0071229440.014
oocyte differentiationGO:000999420.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
regulation of dna metabolic processGO:00510521530.014
Yeast
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.014
regulation of meiosisGO:004002030.013
negative regulation of cell growthGO:0030308830.013
cellular response to organic cyclic compoundGO:00714071270.013
protein tetramerizationGO:0051262470.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
cellular calcium ion homeostasisGO:00068741170.013
response to biotic stimulusGO:00096072760.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
ossificationGO:00015031210.013
intracellular receptor signaling pathwayGO:00305221040.013
exocytosisGO:0006887710.013
dna repairGO:00062811980.013
response to external biotic stimulusGO:00432072610.013
apoptotic mitochondrial changesGO:0008637570.013
response to nutrient levelsGO:0031667810.013
gtp catabolic processGO:00061842370.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
positive regulation of protein kinase activityGO:00458601900.013
regulation of calcium ion transmembrane transporter activityGO:1901019280.013
rhythmic behaviorGO:000762220.013
cellular response to oxidative stressGO:0034599850.013
organelle assemblyGO:00709251760.013
regulation of intracellular protein transportGO:00331571230.013
regulation of gtp catabolic processGO:00331241800.013
visual behaviorGO:000763220.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of protein targetingGO:1903533910.013
peripheral nervous system developmentGO:000742220.013
response to oxygen levelsGO:00704821000.013
regulation of neural precursor cell proliferationGO:200017740.012
negative regulation of phosphate metabolic processGO:00459362670.012
Rat
positive regulation of catabolic processGO:00098963100.012
regulation of cellular component movementGO:00512703340.012
chromatin modificationGO:00165682980.012
Yeast Mouse
generation of neuronsGO:00486991520.012
positive regulation of gtpase activityGO:00435471660.012
positive regulation of transportGO:00510503360.012
Rat
generation of precursor metabolites and energyGO:0006091680.012
response to growth factorGO:00708482050.012
internal peptidyl lysine acetylationGO:0018393970.012
regulation of rab protein signal transductionGO:0032483390.012
negative regulation of proteolysisGO:00458611320.012
regulation of protein transportGO:00512232130.012
posttranscriptional regulation of gene expressionGO:00106082130.012
response to peptide hormoneGO:0043434610.012
second messenger mediated signalingGO:0019932780.012
glutamine family amino acid metabolic processGO:0009064170.012
regulation of hormone secretionGO:0046883570.012
Rat
regulation of secretionGO:00510461940.012
Rat
positive regulation of developmental processGO:00510943140.012
neuron differentiationGO:00301821380.012
biological adhesionGO:00226103310.012
neurological system processGO:00508771630.012
hormone transportGO:0009914680.012
Rat
embryonic epithelial tube formationGO:000183840.012
negative regulation of growthGO:0045926970.012
adult locomotory behaviorGO:000834410.012
divalent inorganic cation transportGO:00725111580.012
nuclear divisionGO:00002801280.012
macromolecule glycosylationGO:0043413630.012
negative regulation of phosphatase activityGO:0010923610.012
regulation of gtpase activityGO:00430871800.012
intrinsic apoptotic signaling pathwayGO:00971931270.011
cellular response to peptideGO:1901653590.011
neuron projection developmentGO:00311751060.011
nuclear transportGO:00511691790.011
regulation of epithelial cell proliferationGO:00506781130.011
cell morphogenesis involved in differentiationGO:00009041440.011
glycosylationGO:0070085710.011
g protein coupled receptor signaling pathwayGO:00071862070.011
positive regulation of proteolysisGO:00458621420.011
signal transduction by phosphorylationGO:00230142970.011
Rat
cilium morphogenesisGO:0060271750.011
multi organism reproductive processGO:0044703540.011
embryo developmentGO:00097901230.011
cilium assemblyGO:0042384630.011
reproductionGO:0000003630.011
protein localization to nucleusGO:00345041360.011
response to peptideGO:1901652650.011
regulation of dephosphorylationGO:0035303960.011
regulation of anatomical structure morphogenesisGO:00226032860.011
cellular biogenic amine catabolic processGO:004240240.011
rho protein signal transductionGO:0007266260.011
divalent metal ion transportGO:00708381520.011
neuron developmentGO:00486661130.011
cell part morphogenesisGO:00329901370.011
positive regulation of apoptotic signaling pathwayGO:2001235700.011
circadian behaviorGO:004851220.011
neurogenesisGO:00220081690.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
amide transportGO:0042886760.011
Rat
regulation of feeding behaviorGO:006025930.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
regulation of nucleoside metabolic processGO:00091182090.011
microtubule based processGO:00070172100.011
cerebral cortex cell migrationGO:002179530.011
cellular cation homeostasisGO:00300031630.011
negative regulation of protein modification processGO:00314002000.011
Mouse
translationGO:00064121320.011
regulation of protein serine threonine kinase activityGO:00719001790.011
immune system developmentGO:00025201950.010
regulation of cellular response to stressGO:00801352440.010
histone acetylationGO:0016573930.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of protein catabolic processGO:00421761550.010
negative regulation of dephosphorylationGO:0035305630.010
rna interferenceGO:001624640.010
nucleocytoplasmic transportGO:00069131760.010
hemopoiesisGO:00300971800.010
regulation of protein ubiquitinationGO:0031396950.010
response to fatty acidGO:0070542130.010
positive regulation of ion transportGO:0043270870.010
hormone metabolic processGO:0042445610.010
protein localization to mitochondrionGO:0070585250.010
glycerolipid biosynthetic processGO:0045017510.010
response to other organismGO:00517072610.010

SIRT3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.106
inherited metabolic disorderDOID:6552420.106
central nervous system diseaseDOID:3311860.040
nervous system diseaseDOID:8634310.040
disease of cellular proliferationDOID:145661740.025
cancerDOID:1621670.025
amino acid metabolic disorderDOID:9252500.023
neurodegenerative diseaseDOID:12891020.022
organ system cancerDOID:00506861640.021
sensory system diseaseDOID:00501552030.014
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011