Homo sapiens

34 known processes

SIRT5

sirtuin 5

(Aliases: FLJ36950,SIR2L5)

SIRT5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238110.187
cellular amine metabolic processGO:0044106410.177
cellular amino acid metabolic processGO:00065201160.165
cellular ketone metabolic processGO:0042180800.160
amine metabolic processGO:0009308440.146
regulation of cellular ketone metabolic processGO:0010565500.127
regulation of cellular amino acid metabolic processGO:000652160.121
histone modificationGO:00165702510.121
chromatin modificationGO:00165682980.108
peptidyl lysine modificationGO:00182051440.105
oxidation reduction processGO:00551143960.094
negative regulation of cellular amine metabolic processGO:003323930.082
covalent chromatin modificationGO:00165692540.076
protein acylationGO:00435431380.074
post embryonic developmentGO:000979120.071
protein acetylationGO:00064731160.063
peptidyl lysine acetylationGO:00183941010.063
negative regulation of cellular amino acid metabolic processGO:004576320.059
regulation of reactive oxygen species metabolic processGO:2000377410.056
mapk cascadeGO:00001652880.053
negative regulation of cellular protein metabolic processGO:00322693530.049
negative regulation of protein metabolic processGO:00512483910.046
reactive oxygen species metabolic processGO:0072593750.045
nitrogen compound transportGO:00717051910.045
negative regulation of phosphate metabolic processGO:00459362670.044
signal transduction by phosphorylationGO:00230142970.044
lipid metabolic processGO:00066293810.043
protein deacylationGO:0035601390.040
negative regulation of reactive oxygen species metabolic processGO:2000378110.040
multicellular organismal agingGO:001025930.040
regulation of hormone levelsGO:00108171250.038
negative regulation of phosphorus metabolic processGO:00105632670.038
regulation of mapk cascadeGO:00434082620.038
determination of adult lifespanGO:000834020.037
ras protein signal transductionGO:0007265730.035
chromatin organizationGO:00063253510.035
positive regulation of transportGO:00510503360.035
cellular response to endogenous stimulusGO:00714953360.035
peptide hormone secretionGO:0030072500.034
positive regulation of cellular amine metabolic processGO:003324070.034
protein deacetylationGO:0006476380.034
secretionGO:00469032540.033
locomotory behaviorGO:000762610.033
neuroblast proliferationGO:000740540.032
secretion by cellGO:00329402260.032
response to abiotic stimulusGO:00096283360.031
organophosphate catabolic processGO:00464344300.031
negative regulation of intracellular signal transductionGO:19025321830.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
purine nucleotide catabolic processGO:00061954050.030
ribonucleoside catabolic processGO:00424544060.030
female gamete generationGO:000729220.029
small gtpase mediated signal transductionGO:0007264780.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
negative regulation of protein modification processGO:00314002000.029
ribonucleoside triphosphate catabolic processGO:00092033910.029
dna recombinationGO:0006310770.028
purine ribonucleotide catabolic processGO:00091544040.028
purine containing compound catabolic processGO:00725234110.028
negative regulation of cell deathGO:00605483450.028
Rat
negative regulation of phosphorylationGO:00423261740.028
glycosyl compound catabolic processGO:19016584130.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
purine nucleoside triphosphate catabolic processGO:00091463920.027
macromolecule deacylationGO:0098732410.027
regulation of secretionGO:00510461940.027
negative regulation of programmed cell deathGO:00430693210.027
Rat
regulation of secretion by cellGO:19035301770.027
cell morphogenesisGO:00009022960.027
regulation of peptide hormone secretionGO:0090276410.027
regulation of dna metabolic processGO:00510521530.026
cellular macromolecule catabolic processGO:00442653800.026
peptide transportGO:0015833740.026
negative regulation of catalytic activityGO:00430863350.026
protein catabolic processGO:00301633250.026
positive regulation of secretionGO:00510471160.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
nucleoside phosphate catabolic processGO:19012924120.025
cellular component morphogenesisGO:00329893140.025
cellular response to dna damage stimulusGO:00069743790.025
generation of precursor metabolites and energyGO:0006091680.025
cytoplasmic transportGO:00164823790.025
monocarboxylic acid metabolic processGO:00327871850.025
oogenesisGO:004847720.025
regulation of cell cycleGO:00517263930.025
peptide secretionGO:0002790510.025
regulation of cell differentiationGO:00455953930.024
cell projection organizationGO:00300302520.024
regulation of cellular component biogenesisGO:00440872810.024
neuromuscular junction developmentGO:000752830.024
hormone secretionGO:0046879650.024
single organism cellular localizationGO:19025803320.024
nucleoside triphosphate catabolic processGO:00091433940.024
hormone transportGO:0009914680.024
cellular protein catabolic processGO:00442572610.023
nucleoside catabolic processGO:00091644080.023
mitotic cell cycleGO:00002783260.023
nucleoside triphosphate metabolic processGO:00091414220.023
purine ribonucleoside catabolic processGO:00461303980.023
dephosphorylationGO:00163112090.023
membrane organizationGO:00610242920.022
internal protein amino acid acetylationGO:00064751010.022
regulation of transferase activityGO:00513383550.022
protein localization to organelleGO:00333652800.022
positive regulation of hydrolase activityGO:00513453310.022
single organism membrane organizationGO:00448022680.022
positive regulation of phosphorylationGO:00423273940.022
internal peptidyl lysine acetylationGO:0018393970.022
response to oxygen containing compoundGO:19017003690.022
nervous system developmentGO:00073992930.022
cell agingGO:0007569520.022
cellular response to oxygen containing compoundGO:19017012760.022
proteolysis involved in cellular protein catabolic processGO:00516032440.021
memoryGO:000761330.021
regulation of cellular response to stressGO:00801352440.021
cell cell signalingGO:00072671550.021
positive regulation of catabolic processGO:00098963100.021
positive regulation of cellular catabolic processGO:00313312840.021
regulation of hormone secretionGO:0046883570.021
lipid biosynthetic processGO:00086101770.021
erk1 and erk2 cascadeGO:00703711040.021
purine nucleoside catabolic processGO:00061523980.021
insulin secretionGO:0030073390.021
regulation of kinase activityGO:00435493140.021
regulation of nucleotide metabolic processGO:00061402690.020
carbohydrate derivative biosynthetic processGO:19011372070.020
transmembrane transportGO:00550853990.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
regulation of proteolysisGO:00301622930.020
positive regulation of secretion by cellGO:19035321080.020
carbohydrate metabolic processGO:00059752070.020
negative regulation of chromatin silencingGO:003193640.020
negative regulation of cellular component organizationGO:00511292350.020
regulation of peptide transportGO:0090087620.020
hemopoiesisGO:00300971800.020
rhythmic behaviorGO:000762220.020
ribonucleotide catabolic processGO:00092614050.020
histone acetylationGO:0016573930.019
guanosine containing compound metabolic processGO:19010682440.019
rho protein signal transductionGO:0007266260.019
cellular macromolecular complex assemblyGO:00346223240.019
negative regulation of multicellular organismal processGO:00512413170.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of protein localizationGO:00328802960.019
actin filament based processGO:00300292240.019
regulation of protein kinase activityGO:00458592890.019
intracellular protein transportGO:00068862700.019
energy derivation by oxidation of organic compoundsGO:0015980430.019
cell adhesionGO:00071553250.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
regulation of cell cycle processGO:00105642660.018
nucleotide catabolic processGO:00091664080.018
single organism carbohydrate metabolic processGO:00447231930.018
mitochondrion organizationGO:00070051560.018
cellular lipid metabolic processGO:00442553030.018
circadian behaviorGO:004851220.018
purine ribonucleoside metabolic processGO:00461284370.018
histone deacetylationGO:0016575320.018
ubiquitin dependent protein catabolic processGO:00065112060.018
maintenance of locationGO:00512351120.017
spermatid differentiationGO:004851540.017
regulation of establishment of protein localizationGO:00702012420.017
segmentationGO:003528240.017
proteasomal protein catabolic processGO:00104981760.017
regulation of purine nucleotide catabolic processGO:00331212050.017
regulation of purine nucleotide metabolic processGO:19005422640.017
regulation of anatomical structure morphogenesisGO:00226032860.017
positive regulation of cell deathGO:00109422630.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
regulation of cytokine productionGO:00018172320.017
immune responseGO:00069553070.017
defense responseGO:00069523150.017
guanosine containing compound catabolic processGO:19010692390.017
regenerationGO:003109940.016
modification dependent macromolecule catabolic processGO:00436322120.016
negative regulation of hydrolase activityGO:00513461820.016
biological adhesionGO:00226103310.016
response to nitrogen compoundGO:19016981840.016
positive regulation of programmed cell deathGO:00430682490.016
positive regulation of cellular component organizationGO:00511303760.016
organophosphate biosynthetic processGO:00904071630.016
positive regulation of nucleotide metabolic processGO:00459812300.016
morphogenesis of embryonic epitheliumGO:001633140.016
organelle assemblyGO:00709251760.016
cellular protein complex assemblyGO:00436231880.016
protein processingGO:00164852260.016
hindbrain developmentGO:003090230.016
ion transmembrane transportGO:00342203380.016
protein ubiquitinationGO:00165673140.016
dna repairGO:00062811980.016
chemical homeostasisGO:00488783060.016
regulation of cellular component movementGO:00512703340.016
neurotransmitter secretionGO:000726940.016
response to organic cyclic compoundGO:00140702040.016
negative regulation of dna metabolic processGO:0051053570.016
modification dependent protein catabolic processGO:00199412090.015
cytokine productionGO:00018162470.015
oocyte developmentGO:004859910.015
regulation of gene expression epigeneticGO:0040029730.015
protein targetingGO:00066051870.015
peripheral nervous system developmentGO:000742220.015
regulation of nucleotide catabolic processGO:00308112050.015
regulation of peptide secretionGO:0002791420.015
histone h3 acetylationGO:0043966450.015
myeloid cell differentiationGO:00300991170.015
regulation of insulin secretionGO:0050796330.015
cofactor metabolic processGO:0051186870.015
regulation of ras protein signal transductionGO:00465781550.015
small molecule catabolic processGO:0044282920.015
cellular homeostasisGO:00197251960.015
negative regulation of apoptotic processGO:00430663160.015
Rat
protein maturationGO:00516042330.015
regulation of protein catabolic processGO:00421761550.015
fatty acid metabolic processGO:00066311150.015
system processGO:00030083490.015
oocyte differentiationGO:000999420.015
neurogenesisGO:00220081690.015
positive regulation of transferase activityGO:00513472270.015
cell developmentGO:00484683280.015
response to growth factorGO:00708482050.015
positive regulation of protein phosphorylationGO:00019343130.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
spermatid developmentGO:000728640.014
mitotic cell cycle processGO:19030472860.014
positive regulation of apoptotic processGO:00430652460.014
positive regulation of nucleoside metabolic processGO:00459791860.014
negative regulation of cell proliferationGO:00082852280.014
protein modification by small protein conjugationGO:00324463420.014
regulation of cell motilityGO:20001452990.014
ion homeostasisGO:00508012300.014
positive regulation of protein kinase activityGO:00458601900.014
posttranscriptional regulation of gene expressionGO:00106082130.014
regulation of protein transportGO:00512232130.014
positive regulation of nucleotide catabolic processGO:00308131850.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
protein oligomerizationGO:00512591730.014
sulfur compound metabolic processGO:00067901010.014
regulation of response to external stimulusGO:00321012220.014
cation transportGO:00068123310.014
anion transportGO:00068201610.014
regulation of protein maturationGO:19033171500.014
immune system developmentGO:00025201950.014
positive regulation of gtp catabolic processGO:00331261660.013
generation of neuronsGO:00486991520.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
gtp metabolic processGO:00460392390.013
regulation of intracellular transportGO:00323861950.013
adult locomotory behaviorGO:000834410.013
blastoderm segmentationGO:000735020.013
cell part morphogenesisGO:00329901370.013
cell projection assemblyGO:00300311260.013
negative regulation of transportGO:00510511760.013
microtubule based processGO:00070172100.013
positive regulation of gtpase activityGO:00435471660.013
gtp catabolic processGO:00061842370.013
establishment of protein localization to organelleGO:00725941720.013
response to cytokineGO:00340972320.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of protein processingGO:00706131500.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
neuron differentiationGO:00301821380.013
organic hydroxy compound metabolic processGO:19016151470.013
chemotaxisGO:00069351570.013
organic acid biosynthetic processGO:0016053970.013
small molecule biosynthetic processGO:00442831570.013
regulation of cell morphogenesisGO:00226041530.013
positive regulation of developmental processGO:00510943140.013
rna processingGO:00063962550.013
cation transmembrane transportGO:00986552380.013
cation homeostasisGO:00550801890.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of locomotionGO:00400123290.013
anterior posterior axis specificationGO:000994820.013
negative regulation of cell cycleGO:00457861930.013
regulation of gtp catabolic processGO:00331241800.013
positive regulation of immune system processGO:00026842830.013
regulation of cell migrationGO:00303342890.012
positive regulation of kinase activityGO:00336742040.012
embryonic epithelial tube formationGO:000183840.012
cell projection morphogenesisGO:00488581290.012
response to external biotic stimulusGO:00432072610.012
nucleocytoplasmic transportGO:00069131760.012
cell cycle phase transitionGO:00447701730.012
chronological cell agingGO:000130020.012
innate immune responseGO:00450871780.012
nuclear transportGO:00511691790.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of apoptotic signaling pathwayGO:20012331750.012
endosomal transportGO:00161971290.012
negative regulation of cell differentiationGO:00455961710.012
positive regulation of cell proliferationGO:00082843010.012
rab protein signal transductionGO:003248240.012
response to organonitrogen compoundGO:00102431560.012
reactive oxygen species biosynthetic processGO:190340940.012
cell morphogenesis involved in differentiationGO:00009041440.012
positive regulation of organelle organizationGO:00106381950.012
regulation of cell developmentGO:00602841610.012
regulation of growthGO:00400081650.012
vesicle mediated transportGO:00161923710.012
regulation of mitotic cell cycleGO:00073461890.012
cell growthGO:00160491600.012
regulation of ras gtpase activityGO:00323181280.012
associative learningGO:000830610.012
regulation of gtpase activityGO:00430871800.012
organonitrogen compound biosynthetic processGO:19015662000.012
organ formationGO:004864530.012
cellular response to nitrogen compoundGO:19016991440.012
cellular response to organic cyclic compoundGO:00714071270.012
actin cytoskeleton organizationGO:00300362070.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
positive regulation of cellular component movementGO:00512721810.012
regulation of synaptic plasticityGO:004816730.012
agingGO:0007568660.012
nucleoside monophosphate catabolic processGO:00091251590.012
compound eye developmentGO:004874910.012
metencephalon developmentGO:002203720.012
regulation of neural precursor cell proliferationGO:200017740.011
positive regulation of mapk cascadeGO:00434101900.011
response to hormoneGO:00097251750.011
endomembrane system organizationGO:00102561960.011
establishment of protein localization to membraneGO:00901501210.011
regulation of protein serine threonine kinase activityGO:00719001790.011
cellular response to cytokine stimulusGO:00713451810.011
neurological system processGO:00508771630.011
growthGO:00400072020.011
regulation of cytoskeleton organizationGO:00514931770.011
negative regulation of protein processingGO:00109551420.011
nerve developmentGO:002167540.011
circulatory system developmentGO:00723592620.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
coenzyme metabolic processGO:0006732650.011
regulation of defense responseGO:00313471540.011
response to biotic stimulusGO:00096072760.011
negative regulation of organelle organizationGO:00106391260.011
interspecies interaction between organismsGO:00444191560.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
regulation of cell growthGO:00015581350.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of developmental processGO:00510932470.011
cellular response to organonitrogen compoundGO:00714171240.011
cilium morphogenesisGO:0060271750.011
reactive nitrogen species metabolic processGO:200105730.011
cellular chemical homeostasisGO:00550821800.011
positive regulation of cell migrationGO:00303351720.011
syncytium formation by plasma membrane fusionGO:000076820.011
inorganic ion transmembrane transportGO:00986602310.011
tripartite regional subdivisionGO:000735120.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
regulation of peptidase activityGO:00525471800.011
positive regulation of cellular component biogenesisGO:00440891580.011
protein localization to nucleusGO:00345041360.011
negative regulation of protein phosphorylationGO:00019331400.011
neuron developmentGO:00486661130.011
single organism cell adhesionGO:00986021790.011
positive regulation of proteolysisGO:00458621420.011
cardiovascular system developmentGO:00723582620.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
response to other organismGO:00517072610.011
positive regulation of ras gtpase activityGO:00323201170.011
response to radiationGO:00093141510.011
cellular response to abiotic stimulusGO:00712141170.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
cellular response to growth factor stimulusGO:00713631970.011
negative regulation of protein maturationGO:19033181420.010
response to oxygen levelsGO:00704821000.010
matingGO:000761810.010
regulation of protein complex assemblyGO:00432541470.010
monovalent inorganic cation transportGO:00156721280.010
cellular response to lipidGO:00713961270.010
response to inorganic substanceGO:00100351270.010
limbic system developmentGO:002176130.010
regulation of multi organism processGO:00439001570.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
negative regulation of proteolysisGO:00458611320.010
positive regulation of cell motilityGO:20001471770.010
microtubule cytoskeleton organizationGO:00002261760.010
positive regulation of locomotionGO:00400171860.010
response to fungusGO:000962040.010
regulation of cell adhesionGO:00301551660.010
sleepGO:003043120.010
negative regulation of transferase activityGO:00513481240.010
multi organism cellular processGO:00447641560.010
mrna metabolic processGO:00160711750.010
tube closureGO:006060630.010
anterior posterior axis specification embryoGO:000859520.010
positive regulation of protein transportGO:00512221350.010
cellular component assembly involved in morphogenesisGO:0010927730.010
meiosis iGO:000712740.010
atp metabolic processGO:00460341760.010
regulation of endopeptidase activityGO:00525481700.010
epithelial cell proliferationGO:00506731280.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010

SIRT5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.035
disease of metabolismDOID:00146672950.035
nervous system diseaseDOID:8634310.025
central nervous system diseaseDOID:3311860.025
musculoskeletal system diseaseDOID:172230.020
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.016
sensory system diseaseDOID:00501552030.016
neurodegenerative diseaseDOID:12891020.015
organ system cancerDOID:00506861640.015
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
immune system diseaseDOID:29141550.012
retinal diseaseDOID:56791180.012
connective tissue diseaseDOID:651090.011
amino acid metabolic disorderDOID:9252500.011
brain diseaseDOID:936730.010
muscle tissue diseaseDOID:661130.010
muscular diseaseDOID:00800001140.010