Homo sapiens

17 known processes

USP12

ubiquitin specific peptidase 12

(Aliases: UBH1,USP12L1)

USP12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein removalGO:0070646920.130
positive regulation of cell proliferationGO:00082843010.081
dna repairGO:00062811980.074
protein deubiquitinationGO:0016579790.070
amine metabolic processGO:0009308440.066
cellular ketone metabolic processGO:0042180800.062
hippocampus developmentGO:002176610.061
post embryonic developmentGO:000979120.059
regulation of cellular amine metabolic processGO:0033238110.059
nervous system developmentGO:00073992930.057
female gamete generationGO:000729220.054
cellular amino acid metabolic processGO:00065201160.054
protein dephosphorylationGO:0006470810.052
double strand break repair via homologous recombinationGO:0000724500.052
regulation of cellular amino acid metabolic processGO:000652160.052
multicellular organismal agingGO:001025930.048
histone modificationGO:00165702510.048
determination of adult lifespanGO:000834020.045
regulation of cellular ketone metabolic processGO:0010565500.044
positive regulation of cellular amino acid metabolic processGO:004576430.042
regulation of kinase activityGO:00435493140.042
negative regulation of intracellular signal transductionGO:19025321830.041
cellular response to dna damage stimulusGO:00069743790.041
negative regulation of protein metabolic processGO:00512483910.039
oogenesisGO:004847720.038
positive regulation of cellular component organizationGO:00511303760.037
purine ribonucleoside metabolic processGO:00461284370.037
regulation of transferase activityGO:00513383550.037
positive regulation of catabolic processGO:00098963100.037
regulation of protein kinase activityGO:00458592890.037
response to radiationGO:00093141510.035
cytoplasmic transportGO:00164823790.035
glycosyl compound catabolic processGO:19016584130.035
regulation of locomotionGO:00400123290.035
multicellular organismal response to stressGO:003355510.035
positive regulation of cellular amine metabolic processGO:003324070.034
purine nucleoside catabolic processGO:00061523980.034
organophosphate catabolic processGO:00464344300.034
dephosphorylationGO:00163112090.033
negative regulation of catalytic activityGO:00430863350.033
cellular amine metabolic processGO:0044106410.033
negative regulation of cellular protein metabolic processGO:00322693530.033
protein catabolic processGO:00301633250.032
regulation of protein ubiquitinationGO:0031396950.032
chromatin modificationGO:00165682980.032
regulation of cellular response to stressGO:00801352440.032
response to oxygen containing compoundGO:19017003690.031
response to abiotic stimulusGO:00096283360.031
nucleoside triphosphate metabolic processGO:00091414220.031
actin filament based processGO:00300292240.031
double strand break repairGO:00063021010.031
system processGO:00030083490.031
protein modification by small protein conjugationGO:00324463420.030
defense responseGO:00069523150.030
covalent chromatin modificationGO:00165692540.030
purine containing compound catabolic processGO:00725234110.030
negative regulation of phosphorus metabolic processGO:00105632670.029
regulation of epithelial cell proliferationGO:00506781130.029
behavioral response to ethanolGO:004814920.029
head developmentGO:00603221080.029
regulation of cell motilityGO:20001452990.029
purine ribonucleotide catabolic processGO:00091544040.028
regulation of protein localizationGO:00328802960.028
posttranscriptional regulation of gene expressionGO:00106082130.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
protein monoubiquitinationGO:0006513390.027
regulation of protein modification by small protein conjugation or removalGO:19033201070.027
protein ubiquitinationGO:00165673140.027
regulation of establishment of protein localizationGO:00702012420.026
gtp metabolic processGO:00460392390.026
lipid metabolic processGO:00066293810.026
locomotory behaviorGO:000762610.026
nucleoside phosphate catabolic processGO:19012924120.026
regulation of proteolysisGO:00301622930.026
positive regulation of hydrolase activityGO:00513453310.026
cell morphogenesisGO:00009022960.025
regulation of protein transportGO:00512232130.025
central nervous system developmentGO:00074171230.025
negative regulation of multicellular organismal processGO:00512413170.024
oocyte developmentGO:004859910.024
immune responseGO:00069553070.024
nucleotide catabolic processGO:00091664080.024
purine ribonucleoside catabolic processGO:00461303980.023
organ morphogenesisGO:00098871470.023
positive regulation of phosphorylationGO:00423273940.023
small gtpase mediated signal transductionGO:0007264780.023
secretionGO:00469032540.023
single organism cellular localizationGO:19025803320.023
guanosine containing compound metabolic processGO:19010682440.023
anterior posterior axis specificationGO:000994820.022
purine nucleotide catabolic processGO:00061954050.022
gtp catabolic processGO:00061842370.022
regulation of response to external stimulusGO:00321012220.022
negative regulation of protein modification processGO:00314002000.022
protein targetingGO:00066051870.022
negative regulation of cellular amine metabolic processGO:003323930.022
signal transduction by phosphorylationGO:00230142970.022
cerebellum developmentGO:002154920.022
guanosine containing compound catabolic processGO:19010692390.022
ribonucleoside catabolic processGO:00424544060.022
regulation of nucleotide metabolic processGO:00061402690.022
cellular component morphogenesisGO:00329893140.022
regulation of cell cycle processGO:00105642660.022
spermatid differentiationGO:004851540.022
protein localization to organelleGO:00333652800.021
negative regulation of phosphate metabolic processGO:00459362670.021
cellular lipid metabolic processGO:00442553030.021
nucleoside triphosphate catabolic processGO:00091433940.021
positive regulation of transferase activityGO:00513472270.021
positive regulation of kinase activityGO:00336742040.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
cellular macromolecular complex assemblyGO:00346223240.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
positive regulation of epithelial cell proliferationGO:0050679650.021
positive regulation of nucleotide metabolic processGO:00459812300.021
vesicle mediated transportGO:00161923710.021
mapk cascadeGO:00001652880.020
positive regulation of nucleoside metabolic processGO:00459791860.020
positive regulation of transportGO:00510503360.020
mitotic cell cycle processGO:19030472860.020
regulation of gtp catabolic processGO:00331241800.020
reactive oxygen species metabolic processGO:0072593750.020
regenerationGO:003109940.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
negative regulation of apoptotic processGO:00430663160.020
ras protein signal transductionGO:0007265730.019
transmembrane transportGO:00550853990.019
ribonucleotide catabolic processGO:00092614050.019
rho protein signal transductionGO:0007266260.019
cell projection organizationGO:00300302520.019
cellular protein catabolic processGO:00442572610.019
positive regulation of gtp catabolic processGO:00331261660.019
neurotransmitter secretionGO:000726940.019
cellular homeostasisGO:00197251960.019
negative regulation of cellular component organizationGO:00511292350.019
positive regulation of protein kinase activityGO:00458601900.019
carbohydrate derivative biosynthetic processGO:19011372070.019
intracellular protein transportGO:00068862700.019
regulation of cell cycleGO:00517263930.019
positive regulation of programmed cell deathGO:00430682490.019
regulation of cell differentiationGO:00455953930.019
single organism carbohydrate metabolic processGO:00447231930.019
regulation of cellular component movementGO:00512703340.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
positive regulation of cellular catabolic processGO:00313312840.019
neuromuscular junction developmentGO:000752830.019
ribonucleoside triphosphate metabolic processGO:00091994120.018
positive regulation of cell deathGO:00109422630.018
neurogenesisGO:00220081690.018
chemical homeostasisGO:00488783060.018
cation transportGO:00068123310.018
oocyte differentiationGO:000999420.018
forebrain developmentGO:0030900260.018
regulation of intracellular transportGO:00323861950.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of purine nucleotide metabolic processGO:19005422640.018
negative regulation of developmental processGO:00510932470.018
secretion by cellGO:00329402260.018
positive regulation of gtpase activityGO:00435471660.018
positive regulation of immune system processGO:00026842830.018
spermatid developmentGO:000728640.018
protein maturationGO:00516042330.018
rhythmic behaviorGO:000762220.018
small molecule biosynthetic processGO:00442831570.018
ribonucleoside triphosphate catabolic processGO:00092033910.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
negative regulation of transportGO:00510511760.017
hindbrain developmentGO:003090230.017
actin cytoskeleton organizationGO:00300362070.017
regulation of mapk cascadeGO:00434082620.017
peripheral nervous system developmentGO:000742220.017
negative regulation of cell deathGO:00605483450.017
behavioral fear responseGO:000166200.017
positive regulation of mapk cascadeGO:00434101900.017
cell developmentGO:00484683280.017
establishment of protein localization to organelleGO:00725941720.017
dna recombinationGO:0006310770.017
ion transmembrane transportGO:00342203380.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
regulation of protein serine threonine kinase activityGO:00719001790.017
response to light stimulusGO:0009416870.017
hemopoiesisGO:00300971800.017
positive regulation of developmental processGO:00510943140.017
organonitrogen compound biosynthetic processGO:19015662000.017
regulation of nucleoside metabolic processGO:00091182090.017
growthGO:00400072020.017
protein processingGO:00164852260.017
regulation of cellular component biogenesisGO:00440872810.016
membrane organizationGO:00610242920.016
negative regulation of phosphorylationGO:00423261740.016
modification dependent protein catabolic processGO:00199412090.016
regulation of homeostatic processGO:00328441210.016
Yeast
regulation of protein maturationGO:19033171500.016
apoptotic signaling pathwayGO:00971902680.016
segmentationGO:003528240.016
endomembrane system organizationGO:00102561960.016
nucleoside catabolic processGO:00091644080.016
associative learningGO:000830610.016
cell adhesionGO:00071553250.016
epithelial cell proliferationGO:00506731280.016
regulation of cytokine productionGO:00018172320.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
cellular response to oxygen containing compoundGO:19017012760.015
nitrogen compound transportGO:00717051910.015
regulation of peptidase activityGO:00525471800.015
regulation of endopeptidase activityGO:00525481700.015
proteasomal protein catabolic processGO:00104981760.015
cell activationGO:00017752130.015
regulation of secretionGO:00510461940.015
positive regulation of protein phosphorylationGO:00019343130.015
reactive oxygen species biosynthetic processGO:190340940.015
mitotic cell cycleGO:00002783260.015
cellular response to abiotic stimulusGO:00712141170.015
negative regulation of proteolysisGO:00458611320.015
regulation of immune responseGO:00507762010.015
positive regulation of apoptotic processGO:00430652460.015
carbohydrate metabolic processGO:00059752070.015
behaviorGO:00076101120.015
chromatin organizationGO:00063253510.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
innate immune responseGO:00450871780.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
regulation of response to dna damage stimulusGO:2001020940.015
protein acylationGO:00435431380.015
cellular response to endogenous stimulusGO:00714953360.015
response to axon injuryGO:004867810.015
angiogenesisGO:00015251470.015
organophosphate biosynthetic processGO:00904071630.015
negative regulation of protein maturationGO:19033181420.014
response to alcoholGO:0097305640.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
regulation of ras gtpase activityGO:00323181280.014
regulation of purine nucleotide catabolic processGO:00331212050.014
actin mediated cell contractionGO:0070252120.014
negative regulation of programmed cell deathGO:00430693210.014
monocarboxylic acid metabolic processGO:00327871850.014
epithelium developmentGO:00604292270.014
response to woundingGO:00096111680.014
nucleocytoplasmic transportGO:00069131760.014
circulatory system developmentGO:00723592620.014
response to cytokineGO:00340972320.014
regulation of cell migrationGO:00303342890.014
regulation of anatomical structure morphogenesisGO:00226032860.014
regulation of nucleotide catabolic processGO:00308112050.014
cellular response to growth factor stimulusGO:00713631970.014
motor neuron axon guidanceGO:000804520.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
reactive nitrogen species metabolic processGO:200105730.014
metal ion homeostasisGO:00550651690.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
ion homeostasisGO:00508012300.014
rna processingGO:00063962550.014
protein oligomerizationGO:00512591730.014
morphogenesis of embryonic epitheliumGO:001633140.014
metal ion transportGO:00300012720.014
response to external biotic stimulusGO:00432072610.014
regulation of dna metabolic processGO:00510521530.014
regulation of neural precursor cell proliferationGO:200017740.014
generation of neuronsGO:00486991520.014
regulation of protein complex assemblyGO:00432541470.014
cell divisionGO:00513011680.013
blastoderm segmentationGO:000735020.013
response to other organismGO:00517072610.013
g protein coupled receptor signaling pathwayGO:00071862070.013
skeletal system developmentGO:0001501790.013
cation transmembrane transportGO:00986552380.013
positive regulation of nucleotide catabolic processGO:00308131850.013
regulation of cell growthGO:00015581350.013
positive regulation of immune responseGO:00507781590.013
metencephalon developmentGO:002203720.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of secretion by cellGO:19035301770.013
wnt signaling pathwayGO:00160551560.013
response to uvGO:0009411730.013
single organism cell adhesionGO:00986021790.013
negative regulation of transferase activityGO:00513481240.013
positive regulation of cell migrationGO:00303351720.013
positive regulation of cell differentiationGO:00455972110.013
macromolecular complex disassemblyGO:0032984600.013
Yeast
protein localization to nucleusGO:00345041360.013
circadian behaviorGO:004851220.013
negative regulation of cell cycleGO:00457861930.013
regulation of cell morphogenesisGO:00226041530.013
reproductive processGO:00224141060.013
neuroblast proliferationGO:000740540.013
translationGO:00064121320.013
neuron differentiationGO:00301821380.013
cell cycle checkpointGO:00000751170.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
maintenance of locationGO:00512351120.013
actin filament based movementGO:0030048170.013
cation homeostasisGO:00550801890.012
response to organonitrogen compoundGO:00102431560.012
cellular chemical homeostasisGO:00550821800.012
microtubule based processGO:00070172100.012
skin developmentGO:0043588760.012
immune system developmentGO:00025201950.012
response to oxidative stressGO:00069791210.012
response to nitrogen compoundGO:19016981840.012
cellular component disassemblyGO:0022411920.012
Yeast
neurological system processGO:00508771630.012
positive regulation of cellular component movementGO:00512721810.012
cellular metal ion homeostasisGO:00068751460.012
phospholipid metabolic processGO:0006644990.012
blood vessel developmentGO:00015681720.012
nucleoside monophosphate metabolic processGO:00091231910.012
blood vessel morphogenesisGO:00485141620.012
regulation of chromosome organizationGO:00330441030.012
adult locomotory behaviorGO:000834410.012
ubiquitin dependent protein catabolic processGO:00065112060.012
single organism membrane organizationGO:00448022680.012
regulation of cytoskeleton organizationGO:00514931770.012
positive regulation of cellular component biogenesisGO:00440891580.012
carboxylic acid biosynthetic processGO:0046394970.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
cell projection assemblyGO:00300311260.012
response to biotic stimulusGO:00096072760.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of lymphocyte activationGO:00512491030.012
inorganic ion transmembrane transportGO:00986602310.012
regulation of wnt signaling pathwayGO:00301111230.012
organic acid biosynthetic processGO:0016053970.012
biological adhesionGO:00226103310.012
negative regulation of kinase activityGO:00336731060.012
photoreceptor cell differentiationGO:004653020.012
cellular response to organonitrogen compoundGO:00714171240.012
regulation of gtpase activityGO:00430871800.012
cellular protein complex assemblyGO:00436231880.012
negative regulation of cell differentiationGO:00455961710.012
cellular macromolecule catabolic processGO:00442653800.012
limbic system developmentGO:002176130.012
leukocyte activationGO:00453211640.012
tripartite regional subdivisionGO:000735120.012
regulation of defense responseGO:00313471540.012
sequestering of metal ionGO:0051238240.012
regulation of leukocyte activationGO:00026941150.012
response to lipidGO:00339932060.011
regulation of protein processingGO:00706131500.011
nuclear transportGO:00511691790.011
rna interferenceGO:001624640.011
mitotic cell cycle phase transitionGO:00447721620.011
t cell differentiation in thymusGO:003307740.011
tissue regenerationGO:004224630.011
single organism nuclear importGO:19025931040.011
lipid biosynthetic processGO:00086101770.011
positive regulation of protein transportGO:00512221350.011
glycoprotein metabolic processGO:00091001100.011
endosomal transportGO:00161971290.011
cellular cation homeostasisGO:00300031630.011
cardiovascular system developmentGO:00723582620.011
cellular ion homeostasisGO:00068731680.011
cellular response to radiationGO:0071478650.011
regulation of vesicle mediated transportGO:00606271300.011
regulation of ion transportGO:00432691890.011
negative regulation of protein processingGO:00109551420.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
negative regulation of protein kinase activityGO:0006469980.011
cell growthGO:00160491600.011
organic hydroxy compound metabolic processGO:19016151470.011
anion transportGO:00068201610.011
positive regulation of organelle organizationGO:00106381950.011
cell type specific apoptotic processGO:00972851250.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
oxidation reduction processGO:00551143960.011
regulation of protein targetingGO:1903533910.011
somitogenesisGO:000175620.011
cell morphogenesis involved in differentiationGO:00009041440.011
response to fungusGO:000962040.011
negative regulation of organelle organizationGO:00106391260.011
regulation of neurotransmitter secretionGO:004692830.011
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
peptidyl tyrosine modificationGO:00182121700.011
regulation of intracellular protein transportGO:00331571230.011
inorganic cation transmembrane transportGO:00986621940.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
regulation of stress activated mapk cascadeGO:0032872840.011
negative regulation of immune system processGO:00026831360.011
nerve developmentGO:002167540.011
negative regulation of endopeptidase activityGO:0010951840.011
regulation of anatomical structure sizeGO:00900661010.011
sulfur compound metabolic processGO:00067901010.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
nuclear importGO:00511701060.011
embryo developmentGO:00097901230.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
memoryGO:000761330.011
protein acetylationGO:00064731160.011
response to organic cyclic compoundGO:00140702040.011
cellular response to nitrogen compoundGO:19016991440.011
regulation of apoptotic signaling pathwayGO:20012331750.011
cytokine productionGO:00018162470.011
regulation of protein localization to nucleusGO:1900180850.011
tube developmentGO:00352951250.010
mitochondrion organizationGO:00070051560.010
fear responseGO:004259600.010
regulation of ras protein signal transductionGO:00465781550.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
divalent metal ion transportGO:00708381520.010
positive regulation of locomotionGO:00400171860.010
skeletal system morphogenesisGO:0048705240.010
response to hormoneGO:00097251750.010
cell cycle phase transitionGO:00447701730.010
cell projection morphogenesisGO:00488581290.010
regulation of cytoplasmic transportGO:19036491490.010
i kappab kinase nf kappab signalingGO:00072491660.010
cell fate determinationGO:000170930.010
stress activated protein kinase signaling cascadeGO:0031098940.010
vasculature developmentGO:00019441810.010
stem cell divisionGO:001714520.010
plasma membrane organizationGO:00070091150.010
regulation of cell activationGO:00508651250.010
divalent inorganic cation transportGO:00725111580.010
stress activated mapk cascadeGO:0051403930.010
brain developmentGO:0007420970.010
developmental programmed cell deathGO:001062330.010
actin filament organizationGO:00070151280.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
regulation of cell developmentGO:00602841610.010
negative regulation of growthGO:0045926970.010
regulation of protein stabilityGO:0031647870.010
positive regulation of synaptic transmissionGO:005080640.010
regulation of cell divisionGO:00513021160.010
positive regulation of secretionGO:00510471160.010
interspecies interaction between organismsGO:00444191560.010
establishment or maintenance of bipolar cell polarityGO:006124520.010

USP12 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
disease of metabolismDOID:00146672950.019
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
musculoskeletal system diseaseDOID:172230.015
central nervous system diseaseDOID:3311860.015
inherited metabolic disorderDOID:6552420.014
eye and adnexa diseaseDOID:14921500.012
retinal diseaseDOID:56791180.012
eye diseaseDOID:56141490.012
bone diseaseDOID:0080001880.011
connective tissue diseaseDOID:651090.011
immune system diseaseDOID:29141550.010