Homo sapiens

7 known processes

PAPPA2

pappalysin 2

(Aliases: PLAC3,PAPPE,PAPP-A2)

PAPPA2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.188
regulation of cellular amino acid metabolic processGO:000652160.082
post embryonic developmentGO:000979120.081
cellular amine metabolic processGO:0044106410.078
sensory perceptionGO:00076001030.071
regulation of cell differentiationGO:00455953930.070
amine metabolic processGO:0009308440.059
transmembrane transportGO:00550853990.053
positive regulation of cellular amine metabolic processGO:003324070.052
regulation of hormone levelsGO:00108171250.051
positive regulation of transferase activityGO:00513472270.049
cytokine productionGO:00018162470.048
negative regulation of catalytic activityGO:00430863350.048
regulation of transferase activityGO:00513383550.046
regulation of cell cycleGO:00517263930.045
secretion by cellGO:00329402260.045
positive regulation of phosphorylationGO:00423273940.044
regulation of cytokine productionGO:00018172320.043
regulation of protein transportGO:00512232130.043
female gamete generationGO:000729220.043
lipid metabolic processGO:00066293810.043
biological adhesionGO:00226103310.042
cellular ketone metabolic processGO:0042180800.042
negative regulation of protein metabolic processGO:00512483910.042
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.041
regulation of cellular ketone metabolic processGO:0010565500.041
negative regulation of cellular protein metabolic processGO:00322693530.041
neurological system processGO:00508771630.041
cellular amino acid metabolic processGO:00065201160.039
regulation of establishment of protein localizationGO:00702012420.039
anatomical structure formation involved in morphogenesisGO:00486462840.038
cell morphogenesisGO:00009022960.037
cell projection organizationGO:00300302520.037
negative regulation of cell deathGO:00605483450.037
response to external biotic stimulusGO:00432072610.037
regulation of protein localizationGO:00328802960.037
mapk cascadeGO:00001652880.037
anion transportGO:00068201610.036
striated muscle contractionGO:0006941520.035
defense responseGO:00069523150.035
positive regulation of protein phosphorylationGO:00019343130.035
ion homeostasisGO:00508012300.035
immune responseGO:00069553070.034
response to abiotic stimulusGO:00096283360.034
regulation of protein kinase activityGO:00458592890.034
cellular macromolecule catabolic processGO:00442653800.034
cell adhesionGO:00071553250.033
regulation of sequence specific dna binding transcription factor activityGO:00510902110.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
actin filament based processGO:00300292240.032
nervous system developmentGO:00073992930.031
muscle contractionGO:0006936730.031
cellular response to endogenous stimulusGO:00714953360.031
response to other organismGO:00517072610.031
positive regulation of cellular component organizationGO:00511303760.030
response to oxygen containing compoundGO:19017003690.030
response to organic cyclic compoundGO:00140702040.030
determination of adult lifespanGO:000834020.030
chemical homeostasisGO:00488783060.029
positive regulation of developmental processGO:00510943140.029
secretionGO:00469032540.029
chemotaxisGO:00069351570.029
signal transduction by phosphorylationGO:00230142970.029
regulation of secretionGO:00510461940.029
regulation of kinase activityGO:00435493140.029
oogenesisGO:004847720.029
innate immune responseGO:00450871780.029
circulatory system developmentGO:00723592620.028
regulation of secretion by cellGO:19035301770.028
epithelial cell differentiationGO:00308551410.028
positive regulation of mapk cascadeGO:00434101900.028
positive regulation of cytokine productionGO:00018191670.027
negative regulation of phosphorus metabolic processGO:00105632670.027
negative regulation of multicellular organismal processGO:00512413170.027
regulation of cellular amine metabolic processGO:0033238110.027
multicellular organismal agingGO:001025930.027
response to biotic stimulusGO:00096072760.027
protein localization to organelleGO:00333652800.027
divalent inorganic cation homeostasisGO:00725071360.027
blood circulationGO:00080151130.026
negative regulation of protein modification processGO:00314002000.026
positive regulation of protein kinase activityGO:00458601900.026
single organism cell adhesionGO:00986021790.026
regulation of anatomical structure morphogenesisGO:00226032860.026
cation transportGO:00068123310.026
cellular cation homeostasisGO:00300031630.025
cellular component morphogenesisGO:00329893140.025
cellular chemical homeostasisGO:00550821800.025
cardiovascular system developmentGO:00723582620.024
nucleoside triphosphate metabolic processGO:00091414220.024
regulation of cellular response to stressGO:00801352440.024
negative regulation of phosphate metabolic processGO:00459362670.024
neuromuscular junction developmentGO:000752830.024
positive regulation of cell proliferationGO:00082843010.024
response to lipidGO:00339932060.024
metencephalon developmentGO:002203720.024
positive regulation of cellular catabolic processGO:00313312840.024
response to hypoxiaGO:0001666960.024
inorganic ion transmembrane transportGO:00986602310.024
negative regulation of programmed cell deathGO:00430693210.024
response to nitrogen compoundGO:19016981840.023
cellular protein catabolic processGO:00442572610.023
hindbrain developmentGO:003090230.023
cranial nerve developmentGO:002154540.023
organ morphogenesisGO:00098871470.023
Mouse
protein oligomerizationGO:00512591730.023
positive regulation of cell deathGO:00109422630.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
cellular ion homeostasisGO:00068731680.023
purine ribonucleotide catabolic processGO:00091544040.023
cell divisionGO:00513011680.023
purine ribonucleoside metabolic processGO:00461284370.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
mitotic cell cycleGO:00002783260.023
nucleoside phosphate catabolic processGO:19012924120.022
cellular homeostasisGO:00197251960.022
regulation of system processGO:00440571010.022
regulation of blood circulationGO:1903522590.022
cellular response to growth factor stimulusGO:00713631970.022
growthGO:00400072020.022
nucleoside catabolic processGO:00091644080.022
protein catabolic processGO:00301633250.022
positive regulation of programmed cell deathGO:00430682490.022
cellular response to organic cyclic compoundGO:00714071270.022
positive regulation of immune system processGO:00026842830.021
response to hormoneGO:00097251750.021
nerve developmentGO:002167540.021
enzyme linked receptor protein signaling pathwayGO:00071673030.021
response to cytokineGO:00340972320.021
ion transmembrane transportGO:00342203380.021
protein localization to nucleusGO:00345041360.021
negative regulation of cell differentiationGO:00455961710.021
regulation of cellular component movementGO:00512703340.021
actin mediated cell contractionGO:0070252120.021
purine containing compound catabolic processGO:00725234110.021
protein homooligomerizationGO:00512601000.020
neuron differentiationGO:00301821380.020
organophosphate catabolic processGO:00464344300.020
motor neuron axon guidanceGO:000804520.020
generation of neuronsGO:00486991520.020
anatomical structure homeostasisGO:00602491000.020
positive regulation of catabolic processGO:00098963100.020
interspecies interaction between organismsGO:00444191560.020
tube developmentGO:00352951250.020
cell growthGO:00160491600.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
positive regulation of transportGO:00510503360.020
neuron fate commitmentGO:004866320.020
metal ion transportGO:00300012720.020
cytoplasmic transportGO:00164823790.020
taxisGO:00423301570.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
glycosyl compound catabolic processGO:19016584130.020
purine nucleoside catabolic processGO:00061523980.020
neuron developmentGO:00486661130.020
ribonucleoside catabolic processGO:00424544060.019
positive regulation of apoptotic processGO:00430652460.019
regulation of endopeptidase activityGO:00525481700.019
cellular metal ion homeostasisGO:00068751460.019
negative regulation of cell proliferationGO:00082852280.019
organic hydroxy compound metabolic processGO:19016151470.019
locomotory behaviorGO:000762610.019
regulation of cell motilityGO:20001452990.019
muscle system processGO:0003012810.019
protein importGO:00170381300.019
regulation of protein serine threonine kinase activityGO:00719001790.018
cellular macromolecular complex assemblyGO:00346223240.018
response to inorganic substanceGO:00100351270.018
nucleoside triphosphate catabolic processGO:00091433940.018
protein ubiquitinationGO:00165673140.018
circulatory system processGO:00030131130.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
cell developmentGO:00484683280.018
apoptotic signaling pathwayGO:00971902680.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.018
multi organism cellular processGO:00447641560.018
av node cell to bundle of his cell communicationGO:008606740.018
nitrogen compound transportGO:00717051910.018
peripheral nervous system developmentGO:000742220.017
regulation of cellular component biogenesisGO:00440872810.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
divalent inorganic cation transportGO:00725111580.017
protein targetingGO:00066051870.017
metal ion homeostasisGO:00550651690.017
mitotic cell cycle processGO:19030472860.017
protein modification by small protein conjugationGO:00324463420.017
negative regulation of phosphorylationGO:00423261740.017
epithelium developmentGO:00604292270.017
response to growth factorGO:00708482050.017
regulation of proteolysisGO:00301622930.017
negative regulation of intracellular signal transductionGO:19025321830.017
calcium ion homeostasisGO:00550741220.017
vasculature developmentGO:00019441810.017
regulation of cell cycle processGO:00105642660.017
ribonucleotide catabolic processGO:00092614050.017
cardiac right ventricle morphogenesisGO:000321530.017
regulation of body fluid levelsGO:0050878990.017
actin filament based movementGO:0030048170.017
regulation of dna metabolic processGO:00510521530.017
inner ear morphogenesisGO:004247240.017
nucleoside monophosphate metabolic processGO:00091231910.017
vesicle mediated transportGO:00161923710.016
negative regulation of cellular amine metabolic processGO:003323930.016
cellular response to hormone stimulusGO:00328701250.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
negative regulation of developmental processGO:00510932470.016
osteoblast differentiationGO:0001649920.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
single organism cellular localizationGO:19025803320.016
carbohydrate metabolic processGO:00059752070.016
cardiac muscle cell contractionGO:008600340.016
energy homeostasisGO:009700930.016
intracellular protein transportGO:00068862700.016
positive regulation of kinase activityGO:00336742040.016
ribonucleoside triphosphate catabolic processGO:00092033910.016
response to metal ionGO:0010038840.016
amide transportGO:0042886760.016
negative regulation of hydrolase activityGO:00513461820.015
carbohydrate derivative biosynthetic processGO:19011372070.015
regulation of bindingGO:00510981110.015
regulation of protein complex assemblyGO:00432541470.015
blastocyst developmentGO:000182430.015
inorganic cation transmembrane transportGO:00986621940.015
protein secretionGO:0009306980.015
regulation of peptidase activityGO:00525471800.015
angiogenesisGO:00015251470.015
muscle structure developmentGO:0061061980.015
nucleoside monophosphate catabolic processGO:00091251590.015
memoryGO:000761330.015
viral processGO:00160321460.015
purine ribonucleoside catabolic processGO:00461303980.015
cellular protein complex assemblyGO:00436231880.015
ras protein signal transductionGO:0007265730.015
regulation of locomotionGO:00400123290.015
cellular response to cytokine stimulusGO:00713451810.015
purine nucleotide catabolic processGO:00061954050.015
ribonucleoside monophosphate catabolic processGO:00091581580.015
regulation of mapk cascadeGO:00434082620.015
cellular calcium ion homeostasisGO:00068741170.015
organonitrogen compound biosynthetic processGO:19015662000.014
divalent metal ion transportGO:00708381520.014
response to bacteriumGO:00096171440.014
wnt signaling pathwayGO:00160551560.014
organ formationGO:004864530.014
regulation of heart contractionGO:0008016500.014
regulation of membrane potentialGO:0042391950.014
blood vessel morphogenesisGO:00485141620.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
blood vessel developmentGO:00015681720.014
cell part morphogenesisGO:00329901370.014
response to decreased oxygen levelsGO:0036293960.014
positive regulation of secretion by cellGO:19035321080.014
nucleotide catabolic processGO:00091664080.014
regulation of growthGO:00400081650.014
heart contractionGO:0060047620.014
positive regulation of cell differentiationGO:00455972110.014
regulation of mitotic cell cycleGO:00073461890.014
negative regulation of apoptotic processGO:00430663160.014
regulation of homeostatic processGO:00328441210.014
negative regulation of transferase activityGO:00513481240.014
response to oxygen levelsGO:00704821000.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
single organism membrane organizationGO:00448022680.014
negative regulation of cell cycleGO:00457861930.014
positive regulation of secretionGO:00510471160.014
regulation of response to external stimulusGO:00321012220.014
regulation of nucleotide metabolic processGO:00061402690.014
neurogenesisGO:00220081690.014
single organismal cell cell adhesionGO:00163371480.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
associative learningGO:000830610.014
regulation of cell morphogenesisGO:00226041530.014
positive regulation of immune responseGO:00507781590.014
detection of stimulusGO:0051606850.014
central nervous system developmentGO:00074171230.014
regulation of immune responseGO:00507762010.014
hematopoietic or lymphoid organ developmentGO:00485341860.013
segmentationGO:003528240.013
positive regulation of cell cycleGO:00457871400.013
regulation of defense responseGO:00313471540.013
protein targeting to nucleusGO:00447441040.013
regulation of intracellular transportGO:00323861950.013
atp catabolic processGO:00062001570.013
positive regulation of protein transportGO:00512221350.013
neuron projection developmentGO:00311751060.013
response to organonitrogen compoundGO:00102431560.013
positive regulation of nucleotide metabolic processGO:00459812300.013
response to radiationGO:00093141510.013
cerebellum developmentGO:002154920.013
regulation of hormone secretionGO:0046883570.013
regulation of protein secretionGO:0050708860.013
sodium ion transportGO:0006814610.013
regulation of acetylcholine gated cation channel activityGO:190304810.013
regulation of angiogenesisGO:0045765920.013
neuroblast proliferationGO:000740540.013
regulation of multi organism processGO:00439001570.013
embryo developmentGO:00097901230.013
anterior posterior axis specificationGO:000994820.013
cellular response to oxygen containing compoundGO:19017012760.013
dephosphorylationGO:00163112090.013
positive regulation of organelle organizationGO:00106381950.013
cell projection morphogenesisGO:00488581290.013
sensory perception of light stimulusGO:0050953350.013
cation transmembrane transportGO:00986552380.013
peptide hormone secretionGO:0030072500.013
reactive oxygen species metabolic processGO:0072593750.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
cellular response to lipidGO:00713961270.013
membrane organizationGO:00610242920.013
tissue morphogenesisGO:0048729960.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
ossificationGO:00015031210.013
intracellular receptor signaling pathwayGO:00305221040.012
monovalent inorganic cation transportGO:00156721280.012
head developmentGO:00603221080.012
stem cell differentiationGO:0048863930.012
digestive system developmentGO:0055123750.012
regulation of transmembrane transportGO:00347621390.012
behaviorGO:00076101120.012
positive regulation of cellular component biogenesisGO:00440891580.012
cell fate determinationGO:000170930.012
regulation of meiotic cell cycleGO:005144540.012
hemopoiesisGO:00300971800.012
multicellular organismal signalingGO:0035637340.012
negative regulation of cellular component organizationGO:00511292350.012
cell type specific apoptotic processGO:00972851250.012
cardiac muscle contractionGO:0060048340.012
negative regulation of protein phosphorylationGO:00019331400.012
oxidation reduction processGO:00551143960.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of lipid metabolic processGO:0019216960.012
positive regulation of hydrolase activityGO:00513453310.012
regulation of intracellular protein transportGO:00331571230.012
modification dependent protein catabolic processGO:00199412090.012
posttranscriptional regulation of gene expressionGO:00106082130.012
positive regulation of protein secretionGO:0050714600.012
synaptic transmission involved in micturitionGO:006008420.012
reactive nitrogen species metabolic processGO:200105730.012
dna repairGO:00062811980.012
glial cell migrationGO:000834740.012
peptide transportGO:0015833740.012
positive regulation of proteolysisGO:00458621420.012
heart valve formationGO:000318820.012
protein processingGO:00164852260.012
maintenance of locationGO:00512351120.012
cell cycle phase transitionGO:00447701730.011
atp metabolic processGO:00460341760.011
chromatin modificationGO:00165682980.011
regulation of nucleotide catabolic processGO:00308112050.011
blastoderm segmentationGO:000735020.011
single organism carbohydrate metabolic processGO:00447231930.011
tripartite regional subdivisionGO:000735120.011
lipid biosynthetic processGO:00086101770.011
cytokine mediated signaling pathwayGO:00192211090.011
ubiquitin dependent protein catabolic processGO:00065112060.011
response to oxidative stressGO:00069791210.011
muscle cell cellular homeostasisGO:004671630.011
positive regulation of erk1 and erk2 cascadeGO:0070374750.011
protein acylationGO:00435431380.011
regulation of cytokine secretionGO:0050707570.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
regulation of wnt signaling pathwayGO:00301111230.011
covalent chromatin modificationGO:00165692540.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
detection of chemical stimulus involved in sensory perception of smellGO:005091120.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
leukocyte differentiationGO:0002521980.011
nuclear transportGO:00511691790.011
regulation of neural precursor cell proliferationGO:200017740.011
alcohol metabolic processGO:00060661140.011
hormone secretionGO:0046879650.011
rho protein signal transductionGO:0007266260.011
immune system developmentGO:00025201950.011
canonical wnt signaling pathwayGO:00600701160.011
cell substrate adhesionGO:00315891320.011
organic hydroxy compound biosynthetic processGO:1901617710.011
regulation of purine nucleotide catabolic processGO:00331212050.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
establishment of protein localization to organelleGO:00725941720.011
peptidyl tyrosine modificationGO:00182121700.011
limbic system developmentGO:002176130.011
regulation of cytoplasmic transportGO:19036491490.011
cellular response to abiotic stimulusGO:00712141170.011
negative regulation of cell cycle processGO:00109481210.011
regulation of cell growthGO:00015581350.011
response to axon injuryGO:004867810.011
negative regulation of transportGO:00510511760.011
trophectodermal cell differentiationGO:000182930.011
response to fungusGO:000962040.011
regulation of response to dna damage stimulusGO:2001020940.011
cellular lipid metabolic processGO:00442553030.011
regulation of cardiac muscle contractionGO:0055117330.010
negative regulation of locomotionGO:00400131180.010
negative regulation of cell motilityGO:20001461040.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
salivary gland morphogenesisGO:000743540.010
i kappab kinase nf kappab signalingGO:00072491660.010
glycoprotein metabolic processGO:00091001100.010
positive regulation of locomotionGO:00400171860.010
visual learningGO:000854210.010
peptidyl tyrosine phosphorylationGO:00181081700.010
gland developmentGO:0048732480.010
peptide secretionGO:0002790510.010
negative regulation of cytokine productionGO:0001818820.010
regulation of protein targetingGO:1903533910.010
nucleocytoplasmic transportGO:00069131760.010
nuclear importGO:00511701060.010
oocyte differentiationGO:000999420.010
phototransductionGO:000760230.010
actin cytoskeleton organizationGO:00300362070.010
regulation of feeding behaviorGO:006025930.010
cation homeostasisGO:00550801890.010
stem cell divisionGO:001714520.010
photoreceptor cell differentiationGO:004653020.010
spermatid differentiationGO:004851540.010
response to extracellular stimulusGO:0009991850.010
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.010
activation of protein kinase activityGO:0032147900.010

PAPPA2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.040
nervous system diseaseDOID:8634310.040
eye diseaseDOID:56141490.029
eye and adnexa diseaseDOID:14921500.029
disease of cellular proliferationDOID:145661740.028
cancerDOID:1621670.028
disease of metabolismDOID:00146672950.022
organ system cancerDOID:00506861640.022
retinal diseaseDOID:56791180.021
disease of mental healthDOID:150700.016
central nervous system diseaseDOID:3311860.013
retinal degenerationDOID:8466890.013
neurodegenerative diseaseDOID:12891020.010