Homo sapiens

42 known processes

KCNJ12

potassium inwardly-rectifying channel, subfamily J, member 12

(Aliases: FLJ14167,IRK2,hIRK1,Kir2.2,hIRK,Kir2.2v,hkir2.2x,kcnj12x,KCNJN1)

KCNJ12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.087
amine metabolic processGO:0009308440.080
cellular amine metabolic processGO:0044106410.078
regulation of cellular amine metabolic processGO:0033238110.074
cellular amino acid metabolic processGO:00065201160.074
regulation of cellular ketone metabolic processGO:0010565500.069
post embryonic developmentGO:000979120.065
regulation of cellular amino acid metabolic processGO:000652160.060
transmembrane transportGO:00550853990.055
locomotory behaviorGO:000762610.051
Fly
cation transportGO:00068123310.051
positive regulation of cellular amino acid metabolic processGO:004576430.047
ion transmembrane transportGO:00342203380.047
positive regulation of cellular amine metabolic processGO:003324070.046
neurotransmitter secretionGO:000726940.042
determination of adult lifespanGO:000834020.041
cation transmembrane transportGO:00986552380.040
segmentationGO:003528240.039
multicellular organismal agingGO:001025930.037
inorganic cation transmembrane transportGO:00986621940.037
neuromuscular junction developmentGO:000752830.037
inorganic ion transmembrane transportGO:00986602310.036
system processGO:00030083490.035
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
purine ribonucleoside metabolic processGO:00461284370.035
female gamete generationGO:000729220.034
organophosphate catabolic processGO:00464344300.033
positive regulation of phosphorylationGO:00423273940.033
response to abiotic stimulusGO:00096283360.033
purine containing compound catabolic processGO:00725234110.033
negative regulation of catalytic activityGO:00430863350.033
nucleoside triphosphate metabolic processGO:00091414220.033
nervous system developmentGO:00073992930.033
Fly
chemical homeostasisGO:00488783060.033
purine nucleoside triphosphate catabolic processGO:00091463920.033
metal ion transportGO:00300012720.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
cell developmentGO:00484683280.032
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.031
negative regulation of protein metabolic processGO:00512483910.031
oogenesisGO:004847720.031
nucleoside triphosphate catabolic processGO:00091433940.031
purine ribonucleoside catabolic processGO:00461303980.030
positive regulation of transportGO:00510503360.030
negative regulation of cellular protein metabolic processGO:00322693530.030
ribonucleotide catabolic processGO:00092614050.030
nucleoside phosphate catabolic processGO:19012924120.030
ribonucleoside catabolic processGO:00424544060.029
purine nucleoside catabolic processGO:00061523980.029
cellular response to endogenous stimulusGO:00714953360.028
nucleoside catabolic processGO:00091644080.028
ras protein signal transductionGO:0007265730.028
nucleotide catabolic processGO:00091664080.027
membrane organizationGO:00610242920.027
small gtpase mediated signal transductionGO:0007264780.027
ion homeostasisGO:00508012300.027
cell adhesionGO:00071553250.027
positive regulation of cellular component organizationGO:00511303760.027
memoryGO:000761330.027
actin filament based processGO:00300292240.027
cardiac muscle cell contractionGO:008600340.027
glycosyl compound catabolic processGO:19016584130.026
actin filament based movementGO:0030048170.026
purine ribonucleotide catabolic processGO:00091544040.026
immune responseGO:00069553070.026
signal transduction by phosphorylationGO:00230142970.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
purine nucleotide catabolic processGO:00061954050.025
regulation of cellular component biogenesisGO:00440872810.025
positive regulation of protein phosphorylationGO:00019343130.025
hindbrain developmentGO:003090230.025
lipid metabolic processGO:00066293810.025
single organism cellular localizationGO:19025803320.025
mapk cascadeGO:00001652880.025
positive regulation of catabolic processGO:00098963100.025
negative regulation of phosphate metabolic processGO:00459362670.025
adult locomotory behaviorGO:000834410.025
growthGO:00400072020.025
response to oxygen containing compoundGO:19017003690.024
Human
cellular component morphogenesisGO:00329893140.024
Fly
regulation of nucleotide metabolic processGO:00061402690.024
rhythmic behaviorGO:000762220.024
Fly
biological adhesionGO:00226103310.024
positive regulation of hydrolase activityGO:00513453310.024
regulation of protein kinase activityGO:00458592890.024
regulation of kinase activityGO:00435493140.024
cellular lipid metabolic processGO:00442553030.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
cellular chemical homeostasisGO:00550821800.024
regulation of protein localizationGO:00328802960.024
regulation of cell cycleGO:00517263930.023
regulation of transferase activityGO:00513383550.023
negative regulation of cellular amine metabolic processGO:003323930.023
secretion by cellGO:00329402260.023
Human
single organism membrane organizationGO:00448022680.023
positive regulation of cellular catabolic processGO:00313312840.023
protein catabolic processGO:00301633250.023
negative regulation of phosphorus metabolic processGO:00105632670.023
negative regulation of multicellular organismal processGO:00512413170.022
anterior posterior axis specificationGO:000994820.022
cell morphogenesisGO:00009022960.022
Fly
regulation of establishment of protein localizationGO:00702012420.022
cytoplasmic transportGO:00164823790.022
regulation of purine nucleotide metabolic processGO:19005422640.022
neurological system processGO:00508771630.022
Human
cellular response to oxygen containing compoundGO:19017012760.022
blastoderm segmentationGO:000735020.022
regenerationGO:003109940.022
negative regulation of cell deathGO:00605483450.021
regulation of mapk cascadeGO:00434082620.021
protein localization to organelleGO:00333652800.021
regulation of ion transportGO:00432691890.021
cellular macromolecular complex assemblyGO:00346223240.021
cell projection organizationGO:00300302520.021
Fly
cellular homeostasisGO:00197251960.021
regulation of proteolysisGO:00301622930.021
spinal cord developmentGO:002151040.021
positive regulation of cell deathGO:00109422630.021
negative regulation of apoptotic processGO:00430663160.021
striated muscle contractionGO:0006941520.021
Human
negative regulation of hydrolase activityGO:00513461820.020
actin mediated cell contractionGO:0070252120.020
oxidation reduction processGO:00551143960.020
cellular response to dna damage stimulusGO:00069743790.020
secretionGO:00469032540.020
Human
muscle contractionGO:0006936730.020
Human
cellular macromolecule catabolic processGO:00442653800.020
negative regulation of programmed cell deathGO:00430693210.020
mitotic cell cycleGO:00002783260.020
dephosphorylationGO:00163112090.020
circadian behaviorGO:004851220.020
Fly
vesicle mediated transportGO:00161923710.020
regulation of purine nucleotide catabolic processGO:00331212050.019
peripheral nervous system developmentGO:000742220.019
calcium ion transportGO:00068161470.019
regulation of cell cycle processGO:00105642660.019
sodium ion transmembrane transportGO:0035725590.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
Fly
matingGO:000761810.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
positive regulation of programmed cell deathGO:00430682490.019
divalent metal ion transportGO:00708381520.018
single organism carbohydrate metabolic processGO:00447231930.018
Human
defense responseGO:00069523150.018
nerve developmentGO:002167540.018
apoptotic signaling pathwayGO:00971902680.018
regulation of cellular response to stressGO:00801352440.018
positive regulation of apoptotic processGO:00430652460.018
oocyte differentiationGO:000999420.018
reactive oxygen species biosynthetic processGO:190340940.018
positive regulation of nucleotide catabolic processGO:00308131850.018
oocyte developmentGO:004859910.018
cellular protein catabolic processGO:00442572610.018
associative learningGO:000830610.018
regulation of transmembrane transportGO:00347621390.018
intracellular protein transportGO:00068862700.018
regulation of synaptic plasticityGO:004816730.018
negative regulation of protein modification processGO:00314002000.018
regulation of nucleotide catabolic processGO:00308112050.018
spermatid differentiationGO:004851540.018
negative regulation of cellular component organizationGO:00511292350.017
positive regulation of nucleotide metabolic processGO:00459812300.017
response to external biotic stimulusGO:00432072610.017
positive regulation of transferase activityGO:00513472270.017
mitotic cell cycle processGO:19030472860.017
epithelium developmentGO:00604292270.017
metal ion homeostasisGO:00550651690.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
positive regulation of developmental processGO:00510943140.017
carbohydrate metabolic processGO:00059752070.017
Human
protein maturationGO:00516042330.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
anterior posterior axis specification embryoGO:000859520.017
metencephalon developmentGO:002203720.017
maintenance of locationGO:00512351120.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
positive regulation of protein kinase activityGO:00458601900.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of growthGO:00400081650.017
nucleoside monophosphate metabolic processGO:00091231910.017
positive regulation of nucleoside metabolic processGO:00459791860.017
motor neuron axon guidanceGO:000804520.017
cell growthGO:00160491600.017
organophosphate biosynthetic processGO:00904071630.017
response to biotic stimulusGO:00096072760.017
protein targetingGO:00066051870.017
rho protein signal transductionGO:0007266260.017
regulation of intracellular transportGO:00323861950.017
response to radiationGO:00093141510.017
reactive nitrogen species metabolic processGO:200105730.016
regulation of protein transportGO:00512232130.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
monovalent inorganic cation transportGO:00156721280.016
tripartite regional subdivisionGO:000735120.016
muscle system processGO:0003012810.016
Human
organonitrogen compound biosynthetic processGO:19015662000.016
negative regulation of transportGO:00510511760.016
Human
compound eye developmentGO:004874910.016
response to other organismGO:00517072610.016
regulation of nucleoside metabolic processGO:00091182090.016
protein ubiquitinationGO:00165673140.016
regulation of ras protein signal transductionGO:00465781550.016
negative regulation of intracellular signal transductionGO:19025321830.016
regulation of anatomical structure morphogenesisGO:00226032860.016
cytokine productionGO:00018162470.016
regulation of locomotionGO:00400123290.016
negative regulation of cell proliferationGO:00082852280.016
cellular cation homeostasisGO:00300031630.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
cation homeostasisGO:00550801890.016
protein localization to membraneGO:00726571600.016
nitrogen compound transportGO:00717051910.016
Human
atp metabolic processGO:00460341760.016
divalent inorganic cation transportGO:00725111580.016
guanosine containing compound metabolic processGO:19010682440.016
regulation of secretion by cellGO:19035301770.016
Human
protein modification by small protein conjugationGO:00324463420.016
reactive oxygen species metabolic processGO:0072593750.016
cellular ion homeostasisGO:00068731680.016
regulation of membrane potentialGO:0042391950.016
Human Fly
startle responseGO:000196430.016
histone modificationGO:00165702510.016
posttranscriptional regulation of gene expressionGO:00106082130.016
cell cell signalingGO:00072671550.016
Human
small molecule biosynthetic processGO:00442831570.016
negative regulation of cell cycleGO:00457861930.016
regulation of ion transmembrane transportGO:00347651320.016
cellular metal ion homeostasisGO:00068751460.015
spermatid developmentGO:000728640.015
regulation of secretionGO:00510461940.015
Human
covalent chromatin modificationGO:00165692540.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
guanosine containing compound catabolic processGO:19010692390.015
positive regulation of immune system processGO:00026842830.015
regulation of protein serine threonine kinase activityGO:00719001790.015
sodium ion transportGO:0006814610.015
positive regulation of cell proliferationGO:00082843010.015
gtp metabolic processGO:00460392390.015
morphogenesis of embryonic epitheliumGO:001633140.015
response to growth factorGO:00708482050.015
innate immune responseGO:00450871780.015
response to cytokineGO:00340972320.015
regulation of cell differentiationGO:00455953930.015
chromatin organizationGO:00063253510.015
cardiac muscle contractionGO:0060048340.015
regulation of protein catabolic processGO:00421761550.015
divalent inorganic cation homeostasisGO:00725071360.015
nucleoside monophosphate catabolic processGO:00091251590.014
modification dependent protein catabolic processGO:00199412090.014
calcium ion homeostasisGO:00550741220.014
cell fate determinationGO:000170930.014
sensory perception of painGO:001923340.014
proteasomal protein catabolic processGO:00104981760.014
regulation of response to external stimulusGO:00321012220.014
anion transportGO:00068201610.014
regulation of cell adhesionGO:00301551660.014
negative regulation of phosphorylationGO:00423261740.014
calcium ion transmembrane transportGO:0070588760.014
regulation of metal ion transportGO:00109591200.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
embryonic epithelial tube formationGO:000183840.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
response to nitrogen compoundGO:19016981840.014
Human
cerebellum developmentGO:002154920.014
g protein coupled receptor signaling pathwayGO:00071862070.014
regulation of ion transmembrane transporter activityGO:0032412720.014
regulation of cell growthGO:00015581350.014
regulation of neurotransmitter secretionGO:004692830.014
circulatory system developmentGO:00723592620.014
syncytium formation by plasma membrane fusionGO:000076820.014
cellular calcium ion homeostasisGO:00068741170.014
rna processingGO:00063962550.014
modification dependent macromolecule catabolic processGO:00436322120.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
protein oligomerizationGO:00512591730.014
endomembrane system organizationGO:00102561960.014
cellular potassium ion transportGO:0071804600.014
protein processingGO:00164852260.014
cellular protein complex assemblyGO:00436231880.014
positive regulation of organelle organizationGO:00106381950.014
regulation of cellular component movementGO:00512703340.014
Human
blood circulationGO:00080151130.014
Human
positive regulation of mapk cascadeGO:00434101900.014
establishment of protein localization to organelleGO:00725941720.014
cell cycle phase transitionGO:00447701730.014
carboxylic acid biosynthetic processGO:0046394970.013
gtp catabolic processGO:00061842370.013
ubiquitin dependent protein catabolic processGO:00065112060.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
sequestering of metal ionGO:0051238240.013
nucleocytoplasmic transportGO:00069131760.013
inner ear morphogenesisGO:004247240.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of gtp catabolic processGO:00331241800.013
atp catabolic processGO:00062001570.013
microtubule based processGO:00070172100.013
microtubule cytoskeleton organizationGO:00002261760.013
regulation of system processGO:00440571010.013
Human
chromatin modificationGO:00165682980.013
regulation of cell motilityGO:20001452990.013
positive regulation of gtp catabolic processGO:00331261660.013
cellular response to growth factor stimulusGO:00713631970.013
nuclear transportGO:00511691790.013
positive regulation of kinase activityGO:00336742040.013
regulation of muscle system processGO:0090257530.013
Human
organ formationGO:004864530.013
actin cytoskeleton organizationGO:00300362070.013
neurogenesisGO:00220081690.013
Fly
regulation of gtpase activityGO:00430871800.013
negative regulation of catabolic processGO:00098951040.013
generation of neuronsGO:00486991520.013
Fly
regulation of cytoskeleton organizationGO:00514931770.013
response to fungusGO:000962040.013
negative regulation of protein phosphorylationGO:00019331400.013
positive regulation of cellular component movementGO:00512721810.013
alcohol metabolic processGO:00060661140.013
cardiovascular system developmentGO:00723582620.013
peptidyl serine modificationGO:00182091060.013
visual behaviorGO:000763220.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
regulation of cytoplasmic transportGO:19036491490.013
regulation of transporter activityGO:0032409820.013
nucleoside phosphate biosynthetic processGO:19012931090.013
response to axon injuryGO:004867810.013
regulation of apoptotic signaling pathwayGO:20012331750.013
establishment or maintenance of bipolar cell polarityGO:006124520.012
regulation of protein maturationGO:19033171500.012
regulation of transmembrane transporter activityGO:0022898740.012
organic hydroxy compound metabolic processGO:19016151470.012
cranial nerve developmentGO:002154540.012
regulation of protein processingGO:00706131500.012
cell part morphogenesisGO:00329901370.012
Fly
regulation of cell migrationGO:00303342890.012
negative regulation of developmental processGO:00510932470.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
mitotic cell cycle phase transitionGO:00447721620.012
endocytosisGO:00068971590.012
positive regulation of cellular component biogenesisGO:00440891580.012
tissue regenerationGO:004224630.012
neuron projection developmentGO:00311751060.012
Fly
myoblast fusionGO:000752010.012
sequestering of calcium ionGO:0051208170.012
mitochondrion organizationGO:00070051560.012
dna repairGO:00062811980.012
organelle assemblyGO:00709251760.012
sleepGO:003043120.012
cell divisionGO:00513011680.012
response to lipidGO:00339932060.012
peptidyl tyrosine phosphorylationGO:00181081700.012
long term memoryGO:000761620.012
regulation of cytokine productionGO:00018172320.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
peptidyl tyrosine modificationGO:00182121700.012
neuroblast proliferationGO:000740540.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
cellular response to nitrogen compoundGO:19016991440.012
plasma membrane organizationGO:00070091150.012
regulation of multi organism processGO:00439001570.012
regulation of dna metabolic processGO:00510521530.012
regulation of neural precursor cell proliferationGO:200017740.012
monocarboxylic acid metabolic processGO:00327871850.012
regulation of immune responseGO:00507762010.011
cell substrate adhesionGO:00315891320.011
organic acid biosynthetic processGO:0016053970.011
taxisGO:00423301570.011
negative regulation of protein maturationGO:19033181420.011
behaviorGO:00076101120.011
Fly
lipid biosynthetic processGO:00086101770.011
peptidyl serine phosphorylationGO:00181051010.011
protein localization to nucleusGO:00345041360.011
multi organism cellular processGO:00447641560.011
regulation of protein complex assemblyGO:00432541470.011
limbic system developmentGO:002176130.011
morphogenesis of a polarized epitheliumGO:000173830.011
positive regulation of ion transportGO:0043270870.011
regulation of mitotic cell cycleGO:00073461890.011
neural tube formationGO:000184130.011
single organism cell adhesionGO:00986021790.011
regulation of intracellular protein transportGO:00331571230.011
central nervous system developmentGO:00074171230.011
cell projection morphogenesisGO:00488581290.011
Fly
cellular response to cytokine stimulusGO:00713451810.011
peptidyl lysine modificationGO:00182051440.011
response to woundingGO:00096111680.011
positive regulation of gtpase activityGO:00435471660.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of locomotionGO:00400171860.011
negative regulation of proteolysisGO:00458611320.011
action potentialGO:0001508340.011
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.011
cytosolic calcium ion homeostasisGO:0051480890.011
positive regulation of cell differentiationGO:00455972110.011
response to organonitrogen compoundGO:00102431560.011
Human
regulation of ras gtpase activityGO:00323181280.011
photoreceptor cell differentiationGO:004653020.011
blood vessel morphogenesisGO:00485141620.011
visual learningGO:000854210.011
somitogenesisGO:000175620.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
establishment of protein localization to membraneGO:00901501210.011
epithelial cell differentiationGO:00308551410.011
negative regulation of organelle organizationGO:00106391260.011
tube closureGO:006060630.011
positive regulation of cell migrationGO:00303351720.011
neuron developmentGO:00486661130.011
Fly
response to light stimulusGO:0009416870.011
stem cell divisionGO:001714520.011
neuron differentiationGO:00301821380.011
Fly
regulation of actin filament based processGO:00329701410.011
Human
sex determinationGO:000753030.011
positive regulation of cell cycleGO:00457871400.011
cellular response to lipidGO:00713961270.010
regulation of cell developmentGO:00602841610.010
interspecies interaction between organismsGO:00444191560.010
regulation of cell morphogenesisGO:00226041530.010
thymus developmentGO:004853830.010
immune system developmentGO:00025201950.010
cell morphogenesis involved in differentiationGO:00009041440.010
regulation of dephosphorylationGO:0035303960.010
primary neural tube formationGO:001402030.010
regulation of meiotic cell cycleGO:005144540.010
mrna metabolic processGO:00160711750.010
response to activityGO:001482300.010
immune effector processGO:00022521590.010
cellular response to organonitrogen compoundGO:00714171240.010
regulation of vesicle mediated transportGO:00606271300.010
nucleotide biosynthetic processGO:00091651090.010
neural tube closureGO:000184330.010
response to organic cyclic compoundGO:00140702040.010
Human
rna splicingGO:00083801310.010
specification of organ identityGO:001009230.010
epithelial cell proliferationGO:00506731280.010
regulation of endopeptidase activityGO:00525481700.010
negative regulation of protein kinase activityGO:0006469980.010

KCNJ12 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.039
disease of metabolismDOID:00146672950.026
Human
muscle tissue diseaseDOID:661130.024
muscular diseaseDOID:00800001140.024
sensory system diseaseDOID:00501552030.022
Human
nervous system diseaseDOID:8634310.022
Human
inherited metabolic disorderDOID:6552420.021
Human
central nervous system diseaseDOID:3311860.020
myopathyDOID:4231040.020
cardiovascular system diseaseDOID:12871060.018
Human
immune system diseaseDOID:29141550.016
disease of cellular proliferationDOID:145661740.016
eye and adnexa diseaseDOID:14921500.016
Human
cancerDOID:1621670.016
organ system cancerDOID:00506861640.016
connective tissue diseaseDOID:651090.014
eye diseaseDOID:56141490.013
Human
retinal diseaseDOID:56791180.013
Human
neurodegenerative diseaseDOID:12891020.012
heart diseaseDOID:114680.011
brain diseaseDOID:936730.011
bone diseaseDOID:0080001880.011
retinal degenerationDOID:8466890.011
hematopoietic system diseaseDOID:741000.010