Homo sapiens

35 known processes

MLC1

megalencephalic leukoencephalopathy with subcortical cysts 1

(Aliases: LVM,MLC,KIAA0027,VL)

MLC1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.076
regulation of cellular amine metabolic processGO:0033238110.065
cellular amine metabolic processGO:0044106410.063
regulation of cellular amino acid metabolic processGO:000652160.059
post embryonic developmentGO:000979120.059
positive regulation of cellular amine metabolic processGO:003324070.057
amine metabolic processGO:0009308440.056
positive regulation of cellular amino acid metabolic processGO:004576430.048
regulation of cellular ketone metabolic processGO:0010565500.046
cellular ketone metabolic processGO:0042180800.045
organophosphate catabolic processGO:00464344300.044
positive regulation of hydrolase activityGO:00513453310.044
immune responseGO:00069553070.043
nucleoside phosphate catabolic processGO:19012924120.042
positive regulation of developmental processGO:00510943140.041
defense responseGO:00069523150.040
regulation of cellular component movementGO:00512703340.040
positive regulation of cell proliferationGO:00082843010.040
regulation of purine nucleotide metabolic processGO:19005422640.040
nucleotide catabolic processGO:00091664080.040
response to oxygen containing compoundGO:19017003690.040
g protein coupled receptor signaling pathwayGO:00071862070.039
purine ribonucleoside metabolic processGO:00461284370.039
response to abiotic stimulusGO:00096283360.038
cytokine productionGO:00018162470.038
determination of adult lifespanGO:000834020.037
negative regulation of protein metabolic processGO:00512483910.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
ribonucleoside catabolic processGO:00424544060.036
organonitrogen compound biosynthetic processGO:19015662000.035
purine ribonucleotide catabolic processGO:00091544040.034
purine containing compound catabolic processGO:00725234110.034
regulation of locomotionGO:00400123290.034
multicellular organismal agingGO:001025930.034
ribonucleotide catabolic processGO:00092614050.034
ribonucleoside triphosphate metabolic processGO:00091994120.033
cellular component morphogenesisGO:00329893140.033
negative regulation of multicellular organismal processGO:00512413170.033
cell morphogenesisGO:00009022960.033
nervous system developmentGO:00073992930.032
regulation of cytokine productionGO:00018172320.032
biological adhesionGO:00226103310.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
ras protein signal transductionGO:0007265730.032
nucleoside catabolic processGO:00091644080.031
nucleoside triphosphate metabolic processGO:00091414220.031
negative regulation of programmed cell deathGO:00430693210.031
regulation of cell motilityGO:20001452990.031
vesicle mediated transportGO:00161923710.030
negative regulation of cellular protein metabolic processGO:00322693530.030
regulation of cell cycleGO:00517263930.030
neuromuscular junction developmentGO:000752830.030
positive regulation of phosphorylationGO:00423273940.030
negative regulation of catalytic activityGO:00430863350.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
transmembrane transportGO:00550853990.030
positive regulation of transferase activityGO:00513472270.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
nucleoside triphosphate catabolic processGO:00091433940.029
cellular response to endogenous stimulusGO:00714953360.029
glycosyl compound catabolic processGO:19016584130.029
regulation of cell migrationGO:00303342890.029
regulation of nucleotide metabolic processGO:00061402690.029
regulation of protein localizationGO:00328802960.029
locomotory behaviorGO:000762610.028
regulation of transferase activityGO:00513383550.028
cell adhesionGO:00071553250.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
regulation of synaptic plasticityGO:004816730.028
purine nucleoside catabolic processGO:00061523980.028
regulation of cell differentiationGO:00455953930.028
female gamete generationGO:000729220.027
cellular response to dna damage stimulusGO:00069743790.027
cell developmentGO:00484683280.027
hindbrain developmentGO:003090230.027
regulation of anatomical structure morphogenesisGO:00226032860.027
organophosphate biosynthetic processGO:00904071630.027
system processGO:00030083490.027
purine nucleotide catabolic processGO:00061954050.027
cellular homeostasisGO:00197251960.026
positive regulation of purine nucleotide metabolic processGO:19005442270.026
negative regulation of cellular amine metabolic processGO:003323930.026
positive regulation of protein phosphorylationGO:00019343130.026
cell projection organizationGO:00300302520.026
cytoplasmic transportGO:00164823790.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
positive regulation of cellular component organizationGO:00511303760.026
response to external biotic stimulusGO:00432072610.026
regulation of cell cycle processGO:00105642660.026
small gtpase mediated signal transductionGO:0007264780.025
positive regulation of nucleotide metabolic processGO:00459812300.025
positive regulation of cell differentiationGO:00455972110.025
negative regulation of developmental processGO:00510932470.025
oogenesisGO:004847720.025
positive regulation of cell deathGO:00109422630.025
cation homeostasisGO:00550801890.025
membrane organizationGO:00610242920.025
positive regulation of immune system processGO:00026842830.025
innate immune responseGO:00450871780.025
regulation of protein kinase activityGO:00458592890.025
negative regulation of cellular component organizationGO:00511292350.025
signal transduction by phosphorylationGO:00230142970.024
ion transmembrane transportGO:00342203380.024
positive regulation of cytokine productionGO:00018191670.024
purine ribonucleoside catabolic processGO:00461303980.024
peripheral nervous system developmentGO:000742220.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
negative regulation of phosphorus metabolic processGO:00105632670.024
positive regulation of apoptotic processGO:00430652460.024
generation of neuronsGO:00486991520.023
lipid biosynthetic processGO:00086101770.023
positive regulation of transportGO:00510503360.023
cellular macromolecule catabolic processGO:00442653800.023
negative regulation of cell deathGO:00605483450.023
positive regulation of protein kinase activityGO:00458601900.023
neuron differentiationGO:00301821380.023
ion homeostasisGO:00508012300.023
carbohydrate derivative biosynthetic processGO:19011372070.023
oxidation reduction processGO:00551143960.023
regulation of kinase activityGO:00435493140.023
positive regulation of locomotionGO:00400171860.022
single organism cellular localizationGO:19025803320.022
neurological system processGO:00508771630.022
motor neuron axon guidanceGO:000804520.022
mitotic cell cycle processGO:19030472860.022
positive regulation of synaptic transmissionGO:005080640.022
single organism membrane organizationGO:00448022680.022
regulation of establishment of protein localizationGO:00702012420.022
negative regulation of cell proliferationGO:00082852280.022
positive regulation of programmed cell deathGO:00430682490.022
guanosine containing compound metabolic processGO:19010682440.021
regenerationGO:003109940.021
positive regulation of catabolic processGO:00098963100.021
tissue migrationGO:00901301190.021
response to lipidGO:00339932060.021
positive regulation of cellular catabolic processGO:00313312840.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
regulation of immune responseGO:00507762010.021
mitotic cell cycleGO:00002783260.021
segmentationGO:003528240.021
mapk cascadeGO:00001652880.021
rhythmic behaviorGO:000762220.021
protein catabolic processGO:00301633250.021
guanosine containing compound catabolic processGO:19010692390.021
nerve developmentGO:002167540.021
response to biotic stimulusGO:00096072760.021
positive regulation of cell motilityGO:20001471770.021
apoptotic signaling pathwayGO:00971902680.021
associative learningGO:000830610.021
negative regulation of protein modification processGO:00314002000.021
protein maturationGO:00516042330.021
reactive oxygen species metabolic processGO:0072593750.021
negative regulation of phosphate metabolic processGO:00459362670.020
anion transportGO:00068201610.020
protein processingGO:00164852260.020
neurogenesisGO:00220081690.020
cellular metal ion homeostasisGO:00068751460.020
protein localization to organelleGO:00333652800.020
cellular cation homeostasisGO:00300031630.020
response to other organismGO:00517072610.020
regulation of nucleoside metabolic processGO:00091182090.020
metal ion homeostasisGO:00550651690.020
blood vessel developmentGO:00015681720.019
negative regulation of apoptotic processGO:00430663160.019
lipid metabolic processGO:00066293810.019
secretionGO:00469032540.019
negative regulation of gliogenesisGO:001401430.019
dephosphorylationGO:00163112090.019
gtp catabolic processGO:00061842370.019
negative regulation of cell cycleGO:00457861930.019
cellular macromolecular complex assemblyGO:00346223240.019
vasculature developmentGO:00019441810.019
reactive oxygen species biosynthetic processGO:190340940.019
cellular ion homeostasisGO:00068731680.019
regulation of proteolysisGO:00301622930.019
memoryGO:000761330.019
spermatid differentiationGO:004851540.019
neuron fate commitmentGO:004866320.019
chemical homeostasisGO:00488783060.019
blood vessel morphogenesisGO:00485141620.019
metal ion transportGO:00300012720.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
response to woundingGO:00096111680.019
gtp metabolic processGO:00460392390.018
blood circulationGO:00080151130.018
protein localization to membraneGO:00726571600.018
regulation of purine nucleotide catabolic processGO:00331212050.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
cellular response to cytokine stimulusGO:00713451810.018
cardiovascular system developmentGO:00723582620.018
regulation of neural precursor cell proliferationGO:200017740.018
regulation of nucleotide catabolic processGO:00308112050.018
protein ubiquitinationGO:00165673140.018
regulation of cellular response to stressGO:00801352440.018
cell fate determinationGO:000170930.018
adult locomotory behaviorGO:000834410.018
divalent metal ion transportGO:00708381520.018
negative regulation of hydrolase activityGO:00513461820.018
cellular protein catabolic processGO:00442572610.018
protein modification by small protein conjugationGO:00324463420.018
regulation of secretionGO:00510461940.018
endomembrane system organizationGO:00102561960.018
response to hormoneGO:00097251750.017
cardiac muscle cell contractionGO:008600340.017
cellular response to oxygen containing compoundGO:19017012760.017
maintenance of locationGO:00512351120.017
inorganic cation transmembrane transportGO:00986621940.017
response to radiationGO:00093141510.017
neuroblast proliferationGO:000740540.017
regulation of response to external stimulusGO:00321012220.017
response to growth factorGO:00708482050.017
cellular chemical homeostasisGO:00550821800.017
actin filament based processGO:00300292240.017
regulation of secretion by cellGO:19035301770.017
peptidyl tyrosine phosphorylationGO:00181081700.017
positive regulation of cell migrationGO:00303351720.017
forebrain generation of neuronsGO:002187230.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
purine nucleotide biosynthetic processGO:0006164840.017
positive regulation of mapk cascadeGO:00434101900.017
regulation of cell morphogenesisGO:00226041530.017
response to fungusGO:000962040.017
single organism cell adhesionGO:00986021790.017
carboxylic acid catabolic processGO:0046395710.017
regulation of cell developmentGO:00602841610.017
regulation of dna metabolic processGO:00510521530.017
response to axon injuryGO:004867810.017
negative regulation of phosphorylationGO:00423261740.017
cell cell signalingGO:00072671550.017
cellular response to abiotic stimulusGO:00712141170.017
camp metabolic processGO:0046058610.016
positive regulation of cellular component movementGO:00512721810.016
regulation of intracellular transportGO:00323861950.016
negative regulation of transportGO:00510511760.016
small molecule biosynthetic processGO:00442831570.016
response to organic cyclic compoundGO:00140702040.016
divalent inorganic cation homeostasisGO:00725071360.016
oocyte differentiationGO:000999420.016
photoreceptor cell differentiationGO:004653020.016
angiogenesisGO:00015251470.016
chemotaxisGO:00069351570.016
spermatid developmentGO:000728640.016
mitotic cell cycle phase transitionGO:00447721620.016
glycoprotein metabolic processGO:00091001100.016
glial cell migrationGO:000834740.016
taxisGO:00423301570.016
chromatin organizationGO:00063253510.016
divalent inorganic cation transportGO:00725111580.016
regulation of growthGO:00400081650.016
circulatory system developmentGO:00723592620.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
cellular lipid metabolic processGO:00442553030.016
compound eye developmentGO:004874910.016
positive regulation of gtp catabolic processGO:00331261660.016
oocyte developmentGO:004859910.016
positive regulation of nucleoside metabolic processGO:00459791860.016
reactive nitrogen species metabolic processGO:200105730.016
metencephalon developmentGO:002203720.016
positive regulation of nucleotide catabolic processGO:00308131850.016
immune system developmentGO:00025201950.016
circadian behaviorGO:004851220.016
actin cytoskeleton organizationGO:00300362070.016
positive regulation of kinase activityGO:00336742040.015
peptidyl tyrosine modificationGO:00182121700.015
cell cycle phase transitionGO:00447701730.015
actin mediated cell contractionGO:0070252120.015
regulation of mapk cascadeGO:00434082620.015
protein oligomerizationGO:00512591730.015
intracellular protein transportGO:00068862700.015
central nervous system developmentGO:00074171230.015
neuron developmentGO:00486661130.015
defense response to fungusGO:005083240.015
organic hydroxy compound metabolic processGO:19016151470.015
regulation of gtpase activityGO:00430871800.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
regulation of protein serine threonine kinase activityGO:00719001790.015
cell part morphogenesisGO:00329901370.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
negative regulation of intracellular signal transductionGO:19025321830.015
epithelium developmentGO:00604292270.015
ameboidal type cell migrationGO:00016671350.015
regulation of gtp catabolic processGO:00331241800.015
positive regulation of gliogenesisGO:001401540.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
regulation of hormone levelsGO:00108171250.015
cation transmembrane transportGO:00986552380.015
cell activationGO:00017752130.015
anterior posterior axis specificationGO:000994820.015
nucleoside phosphate biosynthetic processGO:19012931090.015
histone modificationGO:00165702510.014
hemopoiesisGO:00300971800.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
astrocyte differentiationGO:004870840.014
epithelium migrationGO:00901321190.014
small molecule catabolic processGO:0044282920.014
regulation of protein transportGO:00512232130.014
head developmentGO:00603221080.014
spinal cord developmentGO:002151040.014
regulation of protein processingGO:00706131500.014
positive regulation of gtpase activityGO:00435471660.014
nucleotide biosynthetic processGO:00091651090.014
organic anion transportGO:00157111030.014
negative regulation of cell differentiationGO:00455961710.014
regulation of defense responseGO:00313471540.014
regulation of vesicle mediated transportGO:00606271300.014
response to nitrogen compoundGO:19016981840.014
organic acid catabolic processGO:0016054710.014
rho protein signal transductionGO:0007266260.014
atp metabolic processGO:00460341760.014
limbic system developmentGO:002176130.014
cellular response to growth factor stimulusGO:00713631970.014
cyclic nucleotide metabolic processGO:0009187820.014
purine containing compound biosynthetic processGO:0072522880.014
chromatin modificationGO:00165682980.014
regulation of glial cell differentiationGO:004568530.014
epithelial cell migrationGO:00106311190.014
single organism carbohydrate metabolic processGO:00447231930.014
epithelial cell proliferationGO:00506731280.014
response to cytokineGO:00340972320.014
single organismal cell cell adhesionGO:00163371480.014
secretion by cellGO:00329402260.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
posttranscriptional regulation of gene expressionGO:00106082130.014
blastoderm segmentationGO:000735020.014
muscle contractionGO:0006936730.014
nucleoside monophosphate metabolic processGO:00091231910.014
microtubule based processGO:00070172100.014
regulation of cellular component biogenesisGO:00440872810.014
purine nucleoside monophosphate metabolic processGO:00091261860.013
cell divisionGO:00513011680.013
cell growthGO:00160491600.013
multicellular organismal response to stressGO:003355510.013
purine ribonucleotide biosynthetic processGO:0009152790.013
carboxylic acid biosynthetic processGO:0046394970.013
organic acid biosynthetic processGO:0016053970.013
plasma membrane organizationGO:00070091150.013
positive regulation of camp biosynthetic processGO:0030819350.013
cell morphogenesis involved in differentiationGO:00009041440.013
regulation of apoptotic signaling pathwayGO:20012331750.013
response to light stimulusGO:0009416870.013
positive regulation of cell developmentGO:0010720920.013
negative regulation of protein phosphorylationGO:00019331400.013
nitrogen compound transportGO:00717051910.013
regulation of protein maturationGO:19033171500.013
regulation of cyclic nucleotide biosynthetic processGO:0030802490.013
tripartite regional subdivisionGO:000735120.013
regulation of peptidase activityGO:00525471800.013
growthGO:00400072020.013
carbohydrate metabolic processGO:00059752070.013
mitochondrion organizationGO:00070051560.013
negative regulation of protein processingGO:00109551420.013
sex determinationGO:000753030.013
forebrain neuron differentiationGO:002187930.013
establishment of protein localization to membraneGO:00901501210.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
calcium ion homeostasisGO:00550741220.013
dna repairGO:00062811980.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of endopeptidase activityGO:00525481700.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
response to bacteriumGO:00096171440.013
cellular calcium ion homeostasisGO:00068741170.013
cellular response to oxidative stressGO:0034599850.013
regulation of ion transportGO:00432691890.013
wnt signaling pathwayGO:00160551560.013
proteasomal protein catabolic processGO:00104981760.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
modification dependent macromolecule catabolic processGO:00436322120.013
regulation of protein catabolic processGO:00421761550.012
covalent chromatin modificationGO:00165692540.012
visual behaviorGO:000763220.012
neuron projection developmentGO:00311751060.012
monocarboxylic acid metabolic processGO:00327871850.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
negative regulation of protein maturationGO:19033181420.012
cell projection morphogenesisGO:00488581290.012
regulation of blood circulationGO:1903522590.012
regulation of bindingGO:00510981110.012
cyclic purine nucleotide metabolic processGO:0052652600.012
cerebellum developmentGO:002154920.012
nucleoside monophosphate catabolic processGO:00091251590.012
ribonucleotide biosynthetic processGO:0009260810.012
rna processingGO:00063962550.012
neurotransmitter secretionGO:000726940.012
atp catabolic processGO:00062001570.012
modification dependent protein catabolic processGO:00199412090.012
inorganic ion transmembrane transportGO:00986602310.012
positive regulation of organelle organizationGO:00106381950.012
cellular protein complex assemblyGO:00436231880.012
regulation of wnt signaling pathwayGO:00301111230.012
vasodilationGO:004231140.012
neuron projection regenerationGO:003110210.012
organ formationGO:004864530.012
microtubule cytoskeleton organizationGO:00002261760.012
sensory perception of smellGO:000760820.012
extrinsic apoptotic signaling pathwayGO:00971911190.012
positive regulation of secretionGO:00510471160.012
syncytium formation by plasma membrane fusionGO:000076820.012
sleepGO:003043120.012
protein autophosphorylationGO:00467771230.012
cation transportGO:00068123310.012
regulation of epithelial cell proliferationGO:00506781130.012
regulation of meiotic cell cycleGO:005144540.012
endothelial cell migrationGO:0043542860.012
calcium ion transportGO:00068161470.012
negative regulation of synaptic transmissionGO:005080520.012
response to inorganic substanceGO:00100351270.012
regulation of camp metabolic processGO:0030814520.012
somitogenesisGO:000175620.012
actin filament based movementGO:0030048170.012
myeloid cell differentiationGO:00300991170.012
negative regulation of cellular component movementGO:00512711060.012
peptidyl lysine modificationGO:00182051440.012
endocytosisGO:00068971590.012
leukocyte migrationGO:00509001070.012
protein targetingGO:00066051870.012
regulation of cell growthGO:00015581350.012
positive regulation of cell cycleGO:00457871400.012
organelle assemblyGO:00709251760.012
negative regulation of transferase activityGO:00513481240.011
muscle system processGO:0003012810.011
anterior posterior axis specification embryoGO:000859520.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
regulation of ras gtpase activityGO:00323181280.011
negative regulation of cell motilityGO:20001461040.011
fatty acid metabolic processGO:00066311150.011
cellular amide metabolic processGO:0043603690.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
morphogenesis of embryonic epitheliumGO:001633140.011
regulation of cytoskeleton organizationGO:00514931770.011
matingGO:000761810.011
protein secretionGO:0009306980.011
regulation of nervous system developmentGO:0051960880.011
ubiquitin dependent protein catabolic processGO:00065112060.011
regulation of multi organism processGO:00439001570.011
sulfur compound metabolic processGO:00067901010.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
brain developmentGO:0007420970.011
protein localization to nucleusGO:00345041360.011
response to organonitrogen compoundGO:00102431560.011
morphogenesis of a polarized epitheliumGO:000173830.011
negative regulation of catabolic processGO:00098951040.011
second messenger mediated signalingGO:0019932780.011
stem cell divisionGO:001714520.011
nuclear transportGO:00511691790.011
endosomal transportGO:00161971290.011
positive regulation of protein transportGO:00512221350.011
somatic stem cell maintenanceGO:003501940.011
circulatory system processGO:00030131130.011
male genitalia developmentGO:003053910.011
activation of immune responseGO:00022531140.011
sensory perceptionGO:00076001030.011
negative regulation of immune system processGO:00026831360.011
regulation of response to woundingGO:19030341010.011
negative regulation of proteolysisGO:00458611320.011
cellular response to lipidGO:00713961270.011
blood coagulationGO:0007596760.011
negative regulation of organelle organizationGO:00106391260.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
cellular response to organonitrogen compoundGO:00714171240.011
cellular modified amino acid metabolic processGO:0006575640.011
cellular response to nitrogen compoundGO:19016991440.011
protein localization to plasma membraneGO:0072659930.011
positive regulation of immune responseGO:00507781590.011
rna interferenceGO:001624640.011
regulation of dephosphorylationGO:0035303960.011
cyclic nucleotide biosynthetic processGO:0009190610.011
ribose phosphate biosynthetic processGO:0046390820.011
negative regulation of cellular catabolic processGO:0031330830.011
negative regulation of protein kinase activityGO:0006469980.011

MLC1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.037
nervous system diseaseDOID:8634310.030
sensory system diseaseDOID:00501552030.030
inherited metabolic disorderDOID:6552420.027
disease of metabolismDOID:00146672950.027
central nervous system diseaseDOID:3311860.018
hematopoietic system diseaseDOID:741000.018
eye and adnexa diseaseDOID:14921500.017
connective tissue diseaseDOID:651090.016
musculoskeletal system diseaseDOID:172230.016
eye diseaseDOID:56141490.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
neurodegenerative diseaseDOID:12891020.015
bone diseaseDOID:0080001880.015
retinal diseaseDOID:56791180.014
organ system cancerDOID:00506861640.014
disease of mental healthDOID:150700.011
retinal degenerationDOID:8466890.011