Homo sapiens

76 known processes

EGLN2

egl nine homolog 2 (C. elegans)

(Aliases: EIT6,HPH-3,HPH-1,DKFZp434E026,PHD1,HIFPH1,FLJ95603,HIF-PH1)

EGLN2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.096
nucleoside phosphate catabolic processGO:19012924120.088
female gamete generationGO:000729220.088
oogenesisGO:004847720.078
determination of adult lifespanGO:000834020.066
positive regulation of hydrolase activityGO:00513453310.061
Human
purine containing compound catabolic processGO:00725234110.057
regulation of sequence specific dna binding transcription factor activityGO:00510902110.057
Human
positive regulation of programmed cell deathGO:00430682490.057
Human
purine ribonucleoside metabolic processGO:00461284370.056
nucleoside triphosphate metabolic processGO:00091414220.056
purine nucleotide catabolic processGO:00061954050.055
multicellular organismal agingGO:001025930.055
positive regulation of cellular catabolic processGO:00313312840.054
organophosphate catabolic processGO:00464344300.054
protein catabolic processGO:00301633250.053
nucleotide catabolic processGO:00091664080.053
response to abiotic stimulusGO:00096283360.051
purine ribonucleotide catabolic processGO:00091544040.050
purine nucleoside catabolic processGO:00061523980.050
cellular amino acid metabolic processGO:00065201160.050
ras protein signal transductionGO:0007265730.049
small gtpase mediated signal transductionGO:0007264780.049
ribonucleoside catabolic processGO:00424544060.048
positive regulation of catabolic processGO:00098963100.048
chemical homeostasisGO:00488783060.047
Human
regulation of cellular ketone metabolic processGO:0010565500.046
regulation of cellular component movementGO:00512703340.046
positive regulation of apoptotic processGO:00430652460.046
Human
single organism cellular localizationGO:19025803320.045
nucleoside triphosphate catabolic processGO:00091433940.045
purine ribonucleoside triphosphate catabolic processGO:00092073910.044
glycosyl compound catabolic processGO:19016584130.044
cellular protein catabolic processGO:00442572610.043
ribonucleotide catabolic processGO:00092614050.043
cytoplasmic transportGO:00164823790.042
nucleoside catabolic processGO:00091644080.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
positive regulation of transportGO:00510503360.042
purine nucleoside triphosphate catabolic processGO:00091463920.042
ribonucleoside triphosphate metabolic processGO:00091994120.041
cellular amine metabolic processGO:0044106410.041
vesicle mediated transportGO:00161923710.041
regulation of protein kinase activityGO:00458592890.041
regulation of locomotionGO:00400123290.041
protein processingGO:00164852260.040
Human
cellular ketone metabolic processGO:0042180800.040
positive regulation of cellular component organizationGO:00511303760.039
purine ribonucleoside catabolic processGO:00461303980.039
regulation of cellular component biogenesisGO:00440872810.039
regulation of nucleotide metabolic processGO:00061402690.038
ribonucleoside triphosphate catabolic processGO:00092033910.038
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
membrane organizationGO:00610242920.035
regulation of protein localizationGO:00328802960.035
cellular macromolecule catabolic processGO:00442653800.034
regulation of anatomical structure morphogenesisGO:00226032860.034
negative regulation of phosphate metabolic processGO:00459362670.034
regulation of purine nucleotide metabolic processGO:19005422640.034
regulation of nucleotide catabolic processGO:00308112050.033
segmentationGO:003528240.033
amine metabolic processGO:0009308440.033
biological adhesionGO:00226103310.033
regulation of purine nucleotide catabolic processGO:00331212050.033
gtp metabolic processGO:00460392390.032
response to oxygen containing compoundGO:19017003690.032
Human
gtp catabolic processGO:00061842370.032
single organism membrane organizationGO:00448022680.032
positive regulation of cell deathGO:00109422630.031
Human
monocarboxylic acid metabolic processGO:00327871850.031
negative regulation of catalytic activityGO:00430863350.031
locomotory behaviorGO:000762610.030
establishment of protein localization to organelleGO:00725941720.030
positive regulation of cellular amine metabolic processGO:003324070.030
blastoderm segmentationGO:000735020.030
regulation of cellular amine metabolic processGO:0033238110.030
negative regulation of phosphorus metabolic processGO:00105632670.030
guanosine containing compound catabolic processGO:19010692390.030
regulation of cell migrationGO:00303342890.030
positive regulation of purine nucleotide catabolic processGO:00331231850.029
positive regulation of nucleotide metabolic processGO:00459812300.029
actin filament based processGO:00300292240.029
regulation of proteolysisGO:00301622930.029
Human
regulation of cellular amino acid metabolic processGO:000652160.029
regulation of kinase activityGO:00435493140.029
cellular component morphogenesisGO:00329893140.028
protein targetingGO:00066051870.028
protein maturationGO:00516042330.028
Human
positive regulation of cellular amino acid metabolic processGO:004576430.028
regulation of cytokine productionGO:00018172320.028
nervous system developmentGO:00073992930.028
protein localization to organelleGO:00333652800.028
positive regulation of locomotionGO:00400171860.028
mitotic cell cycleGO:00002783260.027
regulation of response to external stimulusGO:00321012220.026
positive regulation of hormone biosynthetic processGO:004688640.026
mitotic cell cycle processGO:19030472860.026
cytokine productionGO:00018162470.026
actin cytoskeleton organizationGO:00300362070.026
regulation of transferase activityGO:00513383550.026
anterior posterior axis specificationGO:000994820.026
regulation of cell cycleGO:00517263930.026
negative regulation of programmed cell deathGO:00430693210.026
guanosine containing compound metabolic processGO:19010682440.025
embryonic placenta developmentGO:000189210.025
modification dependent protein catabolic processGO:00199412090.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.024
protein modification by small protein conjugationGO:00324463420.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
growthGO:00400072020.024
cell morphogenesisGO:00009022960.024
apoptotic signaling pathwayGO:00971902680.024
oocyte differentiationGO:000999420.024
regulation of cell motilityGO:20001452990.023
positive regulation of protein phosphorylationGO:00019343130.023
regulation of protein catabolic processGO:00421761550.023
neuromuscular junction developmentGO:000752830.023
regulation of cellular response to stressGO:00801352440.023
cell projection organizationGO:00300302520.023
glycoprotein metabolic processGO:00091001100.023
hemoglobin biosynthetic processGO:004254130.023
protein ubiquitinationGO:00165673140.023
oocyte developmentGO:004859910.023
positive regulation of gtpase activityGO:00435471660.023
cellular response to dna damage stimulusGO:00069743790.023
regulation of nucleoside metabolic processGO:00091182090.023
response to cytokineGO:00340972320.023
i kappab kinase nf kappab signalingGO:00072491660.023
positive regulation of gtp catabolic processGO:00331261660.022
cellular homeostasisGO:00197251960.022
positive regulation of protein kinase activityGO:00458601900.022
negative regulation of multicellular organismal processGO:00512413170.022
positive regulation of nucleoside metabolic processGO:00459791860.022
positive regulation of cellular component movementGO:00512721810.022
negative regulation of protein metabolic processGO:00512483910.022
tripartite regional subdivisionGO:000735120.022
lipid metabolic processGO:00066293810.022
microtubule based processGO:00070172100.022
endomembrane system organizationGO:00102561960.022
positive regulation of phosphorylationGO:00423273940.021
rho protein signal transductionGO:0007266260.021
regulation of secretionGO:00510461940.021
regulation of body fluid levelsGO:0050878990.021
cellular response to oxygen containing compoundGO:19017012760.021
positive regulation of immune system processGO:00026842830.021
ubiquitin dependent protein catabolic processGO:00065112060.021
system processGO:00030083490.021
negative regulation of cellular protein metabolic processGO:00322693530.021
negative regulation of intracellular signal transductionGO:19025321830.020
dephosphorylationGO:00163112090.020
histone modificationGO:00165702510.020
regulation of immune responseGO:00507762010.020
negative regulation of t cell apoptotic processGO:007023340.020
positive regulation of proteolysisGO:00458621420.020
Human
modification dependent macromolecule catabolic processGO:00436322120.020
negative regulation of apoptotic processGO:00430663160.020
positive regulation of transferase activityGO:00513472270.020
regulation of gtp catabolic processGO:00331241800.020
actin filament organizationGO:00070151280.020
negative regulation of cell proliferationGO:00082852280.020
nitrogen compound transportGO:00717051910.020
regulation of cell differentiationGO:00455953930.020
morphogenesis of embryonic epitheliumGO:001633140.020
positive regulation of cell migrationGO:00303351720.020
regulation of ras protein signal transductionGO:00465781550.019
response to oxidative stressGO:00069791210.019
Human
response to hypoxiaGO:0001666960.019
wound healingGO:00420601150.019
immune responseGO:00069553070.019
neuroblast proliferationGO:000740540.019
secretion by cellGO:00329402260.019
positive regulation of protein catabolic processGO:0045732750.019
regulation of intracellular transportGO:00323861950.019
regulation of mapk cascadeGO:00434082620.019
maintenance of locationGO:00512351120.019
regulation of protein transportGO:00512232130.019
cellular lipid metabolic processGO:00442553030.018
ion homeostasisGO:00508012300.018
cell growthGO:00160491600.018
nuclear transportGO:00511691790.018
positive regulation of nucleotide catabolic processGO:00308131850.018
anterior posterior axis specification embryoGO:000859520.018
regenerationGO:003109940.018
cell developmentGO:00484683280.018
positive regulation of secretion by cellGO:19035321080.018
regulation of cysteine type endopeptidase activityGO:20001161270.018
Human
proteasomal protein catabolic processGO:00104981760.018
cellular response to cytokine stimulusGO:00713451810.018
carbohydrate metabolic processGO:00059752070.017
protein localization to membraneGO:00726571600.017
cellular cation homeostasisGO:00300031630.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
positive regulation of cell proliferationGO:00082843010.017
positive regulation of kinase activityGO:00336742040.017
regulation of gtpase activityGO:00430871800.017
spermatid differentiationGO:004851540.017
defense responseGO:00069523150.017
positive regulation of neural precursor cell proliferationGO:200017920.017
response to decreased oxygen levelsGO:0036293960.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
associative learningGO:000830610.017
endocytosisGO:00068971590.017
organonitrogen compound biosynthetic processGO:19015662000.017
negative regulation of cell deathGO:00605483450.017
retina vasculature development in camera type eyeGO:006129830.017
cellular macromolecular complex assemblyGO:00346223240.017
negative regulation of hydrolase activityGO:00513461820.017
positive regulation of cellular component biogenesisGO:00440891580.017
signal transduction by phosphorylationGO:00230142970.017
mitochondrion organizationGO:00070051560.017
response to woundingGO:00096111680.017
transmembrane transportGO:00550853990.016
protein import into nucleusGO:00066061040.016
epithelium migrationGO:00901321190.016
intracellular protein transportGO:00068862700.016
regulation of cell adhesionGO:00301551660.016
cellular protein complex assemblyGO:00436231880.016
negative regulation of phosphorylationGO:00423261740.016
spermatid developmentGO:000728640.016
positive regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141920.016
viral processGO:00160321460.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
regulation of peptide transportGO:0090087620.016
response to growth factorGO:00708482050.016
response to oxygen levelsGO:00704821000.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
cellular response to growth factor stimulusGO:00713631970.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
mapk cascadeGO:00001652880.016
activation of cysteine type endopeptidase activityGO:0097202570.016
Human
positive regulation of protein serine threonine kinase activityGO:00719021190.016
rhythmic behaviorGO:000762220.015
zymogen activationGO:0031638700.015
Human
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
positive regulation of endopeptidase activityGO:0010950840.015
Human
regulation of mitotic cell cycleGO:00073461890.015
neural crest cell migrationGO:000175520.015
response to external biotic stimulusGO:00432072610.015
cell adhesionGO:00071553250.015
circadian behaviorGO:004851220.015
reactive oxygen species biosynthetic processGO:190340940.015
positive regulation of cysteine type endopeptidase activityGO:2001056790.015
Human
positive regulation of developmental processGO:00510943140.015
peptidyl tyrosine phosphorylationGO:00181081700.015
positive regulation of mapk cascadeGO:00434101900.015
embryonic epithelial tube formationGO:000183840.015
regulation of establishment of protein localizationGO:00702012420.015
innate immune responseGO:00450871780.015
regulation of neural precursor cell proliferationGO:200017740.015
single organism cell adhesionGO:00986021790.015
coagulationGO:0050817780.015
regulation of cell morphogenesisGO:00226041530.015
regulation of protein serine threonine kinase activityGO:00719001790.015
interspecies interaction between organismsGO:00444191560.015
negative regulation of cell cycleGO:00457861930.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
Human
release of cytoplasmic sequestered nf kappabGO:000858840.015
positive regulation of protein transportGO:00512221350.015
cardiovascular system developmentGO:00723582620.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
cellular chemical homeostasisGO:00550821800.015
positive regulation of immune responseGO:00507781590.015
peptidyl tyrosine modificationGO:00182121700.015
organelle assemblyGO:00709251760.014
nuclear importGO:00511701060.014
positive regulation of secretionGO:00510471160.014
regulation of vesicle mediated transportGO:00606271300.014
negative regulation of cellular amine metabolic processGO:003323930.014
response to nitrogen compoundGO:19016981840.014
Human
nucleocytoplasmic transportGO:00069131760.014
wnt signaling pathwayGO:00160551560.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.014
Human
endosomal transportGO:00161971290.014
negative regulation of transcription elongation from rna polymerase ii promoterGO:003424440.014
protein localization to nucleusGO:00345041360.014
memoryGO:000761330.014
regulation of secretion by cellGO:19035301770.014
gas homeostasisGO:003348340.014
Human
cell type specific apoptotic processGO:00972851250.014
regulation of endopeptidase activityGO:00525481700.014
Human
negative regulation of cellular component organizationGO:00511292350.014
secretionGO:00469032540.014
organic hydroxy compound metabolic processGO:19016151470.014
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.014
Human
neural tube formationGO:000184130.014
posttranscriptional regulation of gene expressionGO:00106082130.014
cellular response to external stimulusGO:00714961110.014
response to radiationGO:00093141510.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of stress activated mapk cascadeGO:0032872840.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of cell growthGO:00015581350.013
syncytium formation by plasma membrane fusionGO:000076820.013
response to lipidGO:00339932060.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
oxygen homeostasisGO:003236440.013
Human
regulation of synaptic plasticityGO:004816730.013
reactive nitrogen species metabolic processGO:200105730.013
protein importGO:00170381300.013
chromosome segregationGO:00070591140.013
cellular response to oxygen levelsGO:0071453550.013
response to nitric oxideGO:007173140.013
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.013
Human
regulation of cytoplasmic transportGO:19036491490.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
compound eye developmentGO:004874910.013
reproductive processGO:00224141060.013
atp metabolic processGO:00460341760.013
response to extracellular stimulusGO:0009991850.013
regulation of apoptotic signaling pathwayGO:20012331750.013
cellular response to endogenous stimulusGO:00714953360.013
cdc42 protein signal transductionGO:003248840.013
regulation of peptidase activityGO:00525471800.013
Human
angiogenesisGO:00015251470.013
response to other organismGO:00517072610.013
intracellular mrna localizationGO:000829810.013
negative regulation of growthGO:0045926970.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
glycoprotein biosynthetic processGO:0009101910.013
protein targeting to nucleusGO:00447441040.013
organelle fissionGO:00482851490.012
regulation of intracellular protein transportGO:00331571230.012
ameboidal type cell migrationGO:00016671350.012
regulation of vasculature developmentGO:1901342970.012
vesicle organizationGO:0016050620.012
positive regulation of neuroblast proliferationGO:000205220.012
cell fate determinationGO:000170930.012
mitotic nuclear divisionGO:00070671190.012
canonical wnt signaling pathwayGO:00600701160.012
cellular response to nitrogen compoundGO:19016991440.012
amide transportGO:0042886760.012
covalent chromatin modificationGO:00165692540.012
single organism nuclear importGO:19025931040.012
single organismal cell cell adhesionGO:00163371480.012
regulation of phosphatase activityGO:0010921810.012
positive regulation of cell differentiationGO:00455972110.012
regulation of growthGO:00400081650.012
regulation of autophagyGO:0010506520.012
peripheral nervous system developmentGO:000742220.012
microtubule cytoskeleton organizationGO:00002261760.012
t cell differentiation in thymusGO:003307740.012
protein autophosphorylationGO:00467771230.012
positive regulation of cell motilityGO:20001471770.012
behaviorGO:00076101120.012
cellular response to toxic substanceGO:009723740.012
single organism reproductive processGO:0044702980.012
positive regulation of synaptic transmissionGO:005080640.012
regulation of dephosphorylationGO:0035303960.012
cation homeostasisGO:00550801890.012
epithelial cell migrationGO:00106311190.012
peptidyl serine phosphorylationGO:00181051010.012
plasma membrane organizationGO:00070091150.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
positive regulation of peptidase activityGO:0010952880.012
Human
negative regulation of protein modification processGO:00314002000.012
protein oligomerizationGO:00512591730.012
glycerolipid metabolic processGO:00464861070.011
establishment of protein localization to membraneGO:00901501210.011
neurological system processGO:00508771630.011
tissue migrationGO:00901301190.011
lens development in camera type eyeGO:000208820.011
blood coagulationGO:0007596760.011
regulation of cell cycle processGO:00105642660.011
cell activationGO:00017752130.011
mrna metabolic processGO:00160711750.011
long term memoryGO:000761620.011
inflammatory response to woundingGO:009059420.011
stress activated mapk cascadeGO:0051403930.011
cellular response to lipidGO:00713961270.011
primary neural tube formationGO:001402030.011
regulation of meiotic cell cycleGO:005144540.011
blood vessel morphogenesisGO:00485141620.011
visual behaviorGO:000763220.011
cellular response to abiotic stimulusGO:00712141170.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of protein phosphorylationGO:00019331400.011
hemostasisGO:0007599760.011
negative regulation of cell migrationGO:00303361020.011
asymmetric neuroblast divisionGO:005505910.011
cell projection morphogenesisGO:00488581290.011
negative regulation of developmental processGO:00510932470.011
positive regulation of ras gtpase activityGO:00323201170.011
regulation of cytoskeleton organizationGO:00514931770.011
negative regulation of organelle organizationGO:00106391260.011
peptidyl lysine modificationGO:00182051440.011
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.011
head developmentGO:00603221080.011
response to fungusGO:000962040.011
cytokine mediated signaling pathwayGO:00192211090.011
chromatin organizationGO:00063253510.011
activation of immune responseGO:00022531140.011
lymphocyte homeostasisGO:000226040.011
reactive oxygen species metabolic processGO:0072593750.011
regulation of ras gtpase activityGO:00323181280.011
regulation of protein maturationGO:19033171500.011
hemoglobin metabolic processGO:002002730.011
meiotic chromosome segregationGO:004513240.010
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.010
response to biotic stimulusGO:00096072760.010
immune response regulating signaling pathwayGO:0002764970.010
activation of protein kinase activityGO:0032147900.010
regulation of neuroblast proliferationGO:190269230.010
positive regulation of cytokine productionGO:00018191670.010
endothelial cell migrationGO:0043542860.010
cellular metal ion homeostasisGO:00068751460.010
regulation of response to woundingGO:19030341010.010
adult locomotory behaviorGO:000834410.010
negative regulation of cellular catabolic processGO:0031330830.010
autophagyGO:0006914880.010
response to salt stressGO:000965130.010
maintenance of protein locationGO:0045185570.010
circulatory system developmentGO:00723592620.010
nuclear divisionGO:00002801280.010
receptor metabolic processGO:0043112810.010
immune system developmentGO:00025201950.010
rna splicingGO:00083801310.010
negative regulation of catabolic processGO:00098951040.010
positive regulation of protein complex assemblyGO:0031334860.010
cellular response to oxidative stressGO:0034599850.010

EGLN2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.020
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
central nervous system diseaseDOID:3311860.016
nervous system diseaseDOID:8634310.016
immune system diseaseDOID:29141550.015
inherited metabolic disorderDOID:6552420.013
disease of metabolismDOID:00146672950.013
sensory system diseaseDOID:00501552030.013
eye and adnexa diseaseDOID:14921500.012
musculoskeletal system diseaseDOID:172230.011
connective tissue diseaseDOID:651090.011