Homo sapiens

21 known processes

TPCN1

two pore segment channel 1

(Aliases: TPC1,FLJ20612,KIAA1169)

TPCN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553030.087
post embryonic developmentGO:000979120.076
lipid metabolic processGO:00066293810.073
regulation of cellular amino acid metabolic processGO:000652160.062
cellular amino acid metabolic processGO:00065201160.061
amine metabolic processGO:0009308440.060
cation homeostasisGO:00550801890.059
Human
response to oxygen containing compoundGO:19017003690.058
regulation of cellular ketone metabolic processGO:0010565500.058
cellular amine metabolic processGO:0044106410.056
cellular cation homeostasisGO:00300031630.055
Human
cellular ketone metabolic processGO:0042180800.055
ribonucleoside triphosphate metabolic processGO:00091994120.053
regulation of cellular amine metabolic processGO:0033238110.053
ribonucleotide catabolic processGO:00092614050.052
cellular homeostasisGO:00197251960.051
Human
small gtpase mediated signal transductionGO:0007264780.050
ras protein signal transductionGO:0007265730.049
positive regulation of cellular amino acid metabolic processGO:004576430.048
positive regulation of cellular amine metabolic processGO:003324070.047
organophosphate catabolic processGO:00464344300.046
system processGO:00030083490.046
divalent inorganic cation homeostasisGO:00725071360.045
Human
transmembrane transportGO:00550853990.045
nucleotide catabolic processGO:00091664080.045
cellular calcium ion homeostasisGO:00068741170.044
Human
response to lipidGO:00339932060.044
lipid biosynthetic processGO:00086101770.042
ion transmembrane transportGO:00342203380.042
cellular metal ion homeostasisGO:00068751460.042
Human
response to abiotic stimulusGO:00096283360.041
calcium ion homeostasisGO:00550741220.040
Human
purine nucleoside triphosphate metabolic processGO:00091444120.039
purine ribonucleoside metabolic processGO:00461284370.038
determination of adult lifespanGO:000834020.038
cellular ion homeostasisGO:00068731680.038
Human
purine nucleotide catabolic processGO:00061954050.037
multicellular organismal agingGO:001025930.037
purine ribonucleotide catabolic processGO:00091544040.037
inorganic ion transmembrane transportGO:00986602310.037
ribonucleoside catabolic processGO:00424544060.035
nucleoside phosphate catabolic processGO:19012924120.035
purine ribonucleoside catabolic processGO:00461303980.035
nucleoside catabolic processGO:00091644080.035
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
purine containing compound catabolic processGO:00725234110.034
regulation of transferase activityGO:00513383550.034
glycosyl compound catabolic processGO:19016584130.034
chemical homeostasisGO:00488783060.033
Human
positive regulation of cellular component organizationGO:00511303760.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
female gamete generationGO:000729220.033
oxidation reduction processGO:00551143960.033
cation transportGO:00068123310.032
nucleoside triphosphate catabolic processGO:00091433940.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
purine nucleoside catabolic processGO:00061523980.031
actin filament based processGO:00300292240.031
nucleoside triphosphate metabolic processGO:00091414220.030
negative regulation of catalytic activityGO:00430863350.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
positive regulation of hydrolase activityGO:00513453310.029
anion transportGO:00068201610.029
cytoplasmic transportGO:00164823790.029
positive regulation of cellular catabolic processGO:00313312840.029
oogenesisGO:004847720.028
positive regulation of phosphorylationGO:00423273940.028
positive regulation of catabolic processGO:00098963100.028
carbohydrate metabolic processGO:00059752070.028
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of cellular component biogenesisGO:00440872810.027
cellular component morphogenesisGO:00329893140.027
neuromuscular junction developmentGO:000752830.027
regulation of purine nucleotide metabolic processGO:19005422640.027
regulation of kinase activityGO:00435493140.026
cell morphogenesisGO:00009022960.026
negative regulation of protein metabolic processGO:00512483910.026
cell projection organizationGO:00300302520.026
positive regulation of protein phosphorylationGO:00019343130.026
monocarboxylic acid metabolic processGO:00327871850.026
gtp metabolic processGO:00460392390.026
cation transmembrane transportGO:00986552380.025
locomotory behaviorGO:000762610.025
vesicle mediated transportGO:00161923710.025
regulation of protein kinase activityGO:00458592890.025
positive regulation of transportGO:00510503360.025
protein catabolic processGO:00301633250.024
single organism carbohydrate metabolic processGO:00447231930.024
single organism cellular localizationGO:19025803320.024
regenerationGO:003109940.024
cellular macromolecule catabolic processGO:00442653800.024
organonitrogen compound biosynthetic processGO:19015662000.024
small molecule biosynthetic processGO:00442831570.024
negative regulation of cellular component organizationGO:00511292350.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
memoryGO:000761330.024
immune responseGO:00069553070.024
guanosine containing compound metabolic processGO:19010682440.023
gtp catabolic processGO:00061842370.023
cellular macromolecular complex assemblyGO:00346223240.023
cellular protein complex assemblyGO:00436231880.023
regulation of purine nucleotide catabolic processGO:00331212050.023
positive regulation of nucleotide catabolic processGO:00308131850.022
maintenance of locationGO:00512351120.022
regulation of cellular response to stressGO:00801352440.022
positive regulation of transferase activityGO:00513472270.022
regulation of nucleotide catabolic processGO:00308112050.022
secretionGO:00469032540.022
positive regulation of gtp catabolic processGO:00331261660.022
regulation of cell differentiationGO:00455953930.022
regulation of nucleotide metabolic processGO:00061402690.022
protein localization to organelleGO:00333652800.021
metal ion transportGO:00300012720.021
regulation of nucleoside metabolic processGO:00091182090.021
regulation of gtp catabolic processGO:00331241800.021
regulation of protein localizationGO:00328802960.021
nervous system developmentGO:00073992930.021
cell developmentGO:00484683280.021
cellular response to oxygen containing compoundGO:19017012760.021
inorganic cation transmembrane transportGO:00986621940.021
regulation of anatomical structure morphogenesisGO:00226032860.021
ion homeostasisGO:00508012300.021
Human
positive regulation of immune system processGO:00026842830.021
defense responseGO:00069523150.021
single organism membrane organizationGO:00448022680.020
cellular response to endogenous stimulusGO:00714953360.020
protein modification by small protein conjugationGO:00324463420.020
mitotic cell cycle processGO:19030472860.020
positive regulation of nucleoside metabolic processGO:00459791860.020
guanosine containing compound catabolic processGO:19010692390.020
regulation of cell cycleGO:00517263930.020
negative regulation of phosphate metabolic processGO:00459362670.020
response to other organismGO:00517072610.020
dephosphorylationGO:00163112090.020
rho protein signal transductionGO:0007266260.020
fatty acid metabolic processGO:00066311150.020
protein maturationGO:00516042330.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
regulation of cellular component movementGO:00512703340.019
response to external biotic stimulusGO:00432072610.019
intracellular protein transportGO:00068862700.019
endomembrane system organizationGO:00102561960.019
positive regulation of nucleotide metabolic processGO:00459812300.019
carbohydrate derivative biosynthetic processGO:19011372070.019
biological adhesionGO:00226103310.019
rhythmic behaviorGO:000762220.019
protein processingGO:00164852260.019
mitotic cell cycleGO:00002783260.019
positive regulation of gtpase activityGO:00435471660.019
segmentationGO:003528240.018
regulation of establishment of protein localizationGO:00702012420.018
cell adhesionGO:00071553250.018
negative regulation of multicellular organismal processGO:00512413170.018
protein ubiquitinationGO:00165673140.018
signal transduction by phosphorylationGO:00230142970.018
peptidyl tyrosine phosphorylationGO:00181081700.018
positive regulation of kinase activityGO:00336742040.018
regulation of ras protein signal transductionGO:00465781550.018
regulation of small gtpase mediated signal transductionGO:00510561560.018
cellular response to dna damage stimulusGO:00069743790.018
negative regulation of phosphorus metabolic processGO:00105632670.018
carboxylic acid biosynthetic processGO:0046394970.018
regulation of cell motilityGO:20001452990.018
regulation of proteolysisGO:00301622930.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
cellular protein catabolic processGO:00442572610.018
microtubule based processGO:00070172100.017
spermatid differentiationGO:004851540.017
organic acid biosynthetic processGO:0016053970.017
regulation of locomotionGO:00400123290.017
regulation of cell migrationGO:00303342890.017
regulation of gtpase activityGO:00430871800.017
negative regulation of intracellular signal transductionGO:19025321830.017
negative regulation of hydrolase activityGO:00513461820.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
membrane organizationGO:00610242920.017
innate immune responseGO:00450871780.017
negative regulation of cellular amine metabolic processGO:003323930.017
response to extracellular stimulusGO:0009991850.017
negative regulation of organelle organizationGO:00106391260.017
neurological system processGO:00508771630.016
cellular chemical homeostasisGO:00550821800.016
Human
positive regulation of ras gtpase activityGO:00323201170.016
organophosphate biosynthetic processGO:00904071630.016
alcohol metabolic processGO:00060661140.016
peripheral nervous system developmentGO:000742220.016
positive regulation of developmental processGO:00510943140.016
response to organic cyclic compoundGO:00140702040.016
nitrogen compound transportGO:00717051910.016
regulation of cell cycle processGO:00105642660.016
apoptotic signaling pathwayGO:00971902680.016
regulation of secretionGO:00510461940.016
circadian behaviorGO:004851220.016
secretion by cellGO:00329402260.016
chromatin organizationGO:00063253510.016
positive regulation of protein kinase activityGO:00458601900.016
lipid localizationGO:00108761060.016
lipid catabolic processGO:0016042840.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
response to biotic stimulusGO:00096072760.016
blastoderm segmentationGO:000735020.016
cellular lipid catabolic processGO:0044242650.016
regulation of ras gtpase activityGO:00323181280.016
negative regulation of apoptotic processGO:00430663160.015
microtubule cytoskeleton organizationGO:00002261760.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
regulation of protein transportGO:00512232130.015
negative regulation of programmed cell deathGO:00430693210.015
regulation of intracellular transportGO:00323861950.015
negative regulation of cell deathGO:00605483450.015
chromatin modificationGO:00165682980.015
oocyte differentiationGO:000999420.015
protein targetingGO:00066051870.015
response to nutrient levelsGO:0031667810.015
response to cytokineGO:00340972320.015
cytokine productionGO:00018162470.015
regulation of cytoskeleton organizationGO:00514931770.015
actin cytoskeleton organizationGO:00300362070.015
cellular response to cytokine stimulusGO:00713451810.015
oocyte developmentGO:004859910.015
divalent metal ion transportGO:00708381520.015
mapk cascadeGO:00001652880.015
glycerolipid metabolic processGO:00464861070.015
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of response to external stimulusGO:00321012220.014
matingGO:000761810.014
histone modificationGO:00165702510.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
organic hydroxy compound metabolic processGO:19016151470.014
negative regulation of developmental processGO:00510932470.014
regulation of protein complex assemblyGO:00432541470.014
positive regulation of cell proliferationGO:00082843010.014
sulfur compound metabolic processGO:00067901010.014
glycoprotein metabolic processGO:00091001100.014
positive regulation of organelle organizationGO:00106381950.014
response to nitrogen compoundGO:19016981840.014
regulation of protein maturationGO:19033171500.014
anterior posterior axis specificationGO:000994820.014
morphogenesis of embryonic epitheliumGO:001633140.014
spermatid developmentGO:000728640.014
sensory perceptionGO:00076001030.014
organelle assemblyGO:00709251760.014
atp metabolic processGO:00460341760.014
endosomal transportGO:00161971290.014
calcium ion transportGO:00068161470.014
proteasomal protein catabolic processGO:00104981760.014
negative regulation of protein maturationGO:19033181420.014
response to axon injuryGO:004867810.014
covalent chromatin modificationGO:00165692540.014
positive regulation of programmed cell deathGO:00430682490.014
regulation of immune responseGO:00507762010.014
phospholipid metabolic processGO:0006644990.014
adult locomotory behaviorGO:000834410.014
regulation of protein serine threonine kinase activityGO:00719001790.014
negative regulation of protein modification processGO:00314002000.014
small molecule catabolic processGO:0044282920.014
divalent inorganic cation transportGO:00725111580.014
peptidyl tyrosine modificationGO:00182121700.014
growthGO:00400072020.013
cdc42 protein signal transductionGO:003248840.013
regulation of peptidase activityGO:00525471800.013
response to alcoholGO:0097305640.013
cell projection assemblyGO:00300311260.013
photoreceptor cell differentiationGO:004653020.013
long term memoryGO:000761620.013
regulation of secretion by cellGO:19035301770.013
inorganic anion transmembrane transportGO:0098661470.013
neurogenesisGO:00220081690.013
positive regulation of apoptotic processGO:00430652460.013
hindbrain developmentGO:003090230.013
cell part morphogenesisGO:00329901370.013
regulation of vesicle mediated transportGO:00606271300.013
negative regulation of transportGO:00510511760.013
cell growthGO:00160491600.013
organic acid catabolic processGO:0016054710.013
regulation of protein processingGO:00706131500.013
regulation of cytokine productionGO:00018172320.013
reactive nitrogen species metabolic processGO:200105730.013
nucleocytoplasmic transportGO:00069131760.013
positive regulation of synaptic transmissionGO:005080640.013
leukocyte activationGO:00453211640.013
negative regulation of cell proliferationGO:00082852280.013
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of neural precursor cell proliferationGO:200017740.012
cardiovascular system developmentGO:00723582620.012
negative regulation of phosphorylationGO:00423261740.012
regulation of mapk cascadeGO:00434082620.012
anion transmembrane transportGO:0098656760.012
regulation of cell morphogenesisGO:00226041530.012
positive regulation of cell differentiationGO:00455972110.012
reactive oxygen species metabolic processGO:0072593750.012
monocarboxylic acid biosynthetic processGO:0072330670.012
compound eye developmentGO:004874910.012
regulation of cytoplasmic transportGO:19036491490.012
chloride transmembrane transportGO:1902476380.012
posttranscriptional regulation of gene expressionGO:00106082130.012
lipid transportGO:0006869900.012
peptidyl lysine modificationGO:00182051440.012
organic anion transportGO:00157111030.012
regulation of synaptic plasticityGO:004816730.012
protein localization to membraneGO:00726571600.012
regulation of protein catabolic processGO:00421761550.012
embryonic epithelial tube formationGO:000183840.012
modification dependent macromolecule catabolic processGO:00436322120.012
positive regulation of cellular component biogenesisGO:00440891580.012
negative regulation of protein processingGO:00109551420.012
regulation of endopeptidase activityGO:00525481700.012
nuclear transportGO:00511691790.012
actin filament organizationGO:00070151280.012
positive regulation of immune responseGO:00507781590.012
ubiquitin dependent protein catabolic processGO:00065112060.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
monovalent inorganic cation transportGO:00156721280.012
neurotransmitter secretionGO:000726940.012
metal ion homeostasisGO:00550651690.012
Human
positive regulation of cytokine productionGO:00018191670.012
cell cycle phase transitionGO:00447701730.012
cellular response to abiotic stimulusGO:00712141170.012
reactive oxygen species biosynthetic processGO:190340940.012
meiotic chromosome segregationGO:004513240.012
regulation of growthGO:00400081650.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
circulatory system developmentGO:00723592620.012
hemopoiesisGO:00300971800.012
modification dependent protein catabolic processGO:00199412090.012
positive regulation of mapk cascadeGO:00434101900.012
cell divisionGO:00513011680.012
positive regulation of secretionGO:00510471160.012
response to inorganic substanceGO:00100351270.011
positive regulation of cell migrationGO:00303351720.011
salivary gland morphogenesisGO:000743540.011
positive regulation of cell deathGO:00109422630.011
response to hormoneGO:00097251750.011
regulation of apoptotic signaling pathwayGO:20012331750.011
protein oligomerizationGO:00512591730.011
negative regulation of proteolysisGO:00458611320.011
neuroblast proliferationGO:000740540.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of multi organism processGO:00439001570.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of defense responseGO:00313471540.011
syncytium formation by plasma membrane fusionGO:000076820.011
negative regulation of transferase activityGO:00513481240.011
glycerophospholipid metabolic processGO:0006650840.011
organelle fissionGO:00482851490.011
endocytosisGO:00068971590.011
carboxylic acid catabolic processGO:0046395710.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
protein localization to nucleusGO:00345041360.011
atp catabolic processGO:00062001570.011
response to fungusGO:000962040.011
protein acylationGO:00435431380.011
carboxylic acid transportGO:0046942630.011
negative regulation of synaptic transmissionGO:005080520.011
post embryonic organ developmentGO:004856910.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
response to organonitrogen compoundGO:00102431560.011
associative learningGO:000830610.011
nucleoside monophosphate catabolic processGO:00091251590.011
regulation of cell adhesionGO:00301551660.011
rna processingGO:00063962550.011
tissue regenerationGO:004224630.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
limbic system developmentGO:002176130.011
regulation of dna metabolic processGO:00510521530.011
response to activityGO:001482300.011
cilium morphogenesisGO:0060271750.011
regulation of ion transportGO:00432691890.011
response to oxidative stressGO:00069791210.011
regulation of dephosphorylationGO:0035303960.011
positive regulation of protein transportGO:00512221350.011
cell activationGO:00017752130.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
cell substrate adhesionGO:00315891320.011
anterior posterior axis specification embryoGO:000859520.011
tripartite regional subdivisionGO:000735120.011
immune effector processGO:00022521590.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
mitochondrion organizationGO:00070051560.011
response to woundingGO:00096111680.011
immune system developmentGO:00025201950.011
response to salt stressGO:000965130.011
neuron projection regenerationGO:003110210.011
establishment of protein localization to organelleGO:00725941720.010
regulation of actin filament based processGO:00329701410.010
negative regulation of cell cycleGO:00457861930.010
protein importGO:00170381300.010
enzyme linked receptor protein signaling pathwayGO:00071673030.010
positive regulation of locomotionGO:00400171860.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
somatic muscle developmentGO:000752510.010
sensory perception of painGO:001923340.010
negative regulation of cellular component movementGO:00512711060.010
regulation of myeloid leukocyte mediated immunityGO:000288640.010
cell fate determinationGO:000170930.010
positive regulation of cellular component movementGO:00512721810.010
metencephalon developmentGO:002203720.010
morphogenesis of a polarized epitheliumGO:000173830.010
defense response to other organismGO:00985421290.010
epithelium developmentGO:00604292270.010
meiosis iGO:000712740.010
somitogenesisGO:000175620.010
cellular response to external stimulusGO:00714961110.010
g protein coupled receptor signaling pathwayGO:00071862070.010
i kappab kinase nf kappab signalingGO:00072491660.010
regulation of intracellular protein transportGO:00331571230.010
regulation of cell projection organizationGO:00313441070.010
sensory perception of smellGO:000760820.010
negative regulation of cell motilityGO:20001461040.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of lipid metabolic processGO:0019216960.010
sleepGO:003043120.010
positive regulation of cell motilityGO:20001471770.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
negative regulation of protein phosphorylationGO:00019331400.010
neuron developmentGO:00486661130.010

TPCN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.089
disease of metabolismDOID:00146672950.089
musculoskeletal system diseaseDOID:172230.033
immune system diseaseDOID:29141550.027
connective tissue diseaseDOID:651090.022
sensory system diseaseDOID:00501552030.022
nervous system diseaseDOID:8634310.022
central nervous system diseaseDOID:3311860.021
bone diseaseDOID:0080001880.017
organ system cancerDOID:00506861640.017
cancerDOID:1621670.017
disease of cellular proliferationDOID:145661740.017
cardiovascular system diseaseDOID:12871060.015
eye and adnexa diseaseDOID:14921500.015
muscular diseaseDOID:00800001140.015
eye diseaseDOID:56141490.014
muscle tissue diseaseDOID:661130.014
myopathyDOID:4231040.014
neurodegenerative diseaseDOID:12891020.012
carbohydrate metabolic disorderDOID:2978550.012
hematopoietic system diseaseDOID:741000.011
retinal diseaseDOID:56791180.011
brain diseaseDOID:936730.010
disease of mental healthDOID:150700.010