Homo sapiens

121 known processes

FURIN

furin (paired basic amino acid cleaving enzyme)

(Aliases: PACE,FUR,SPC1,PCSK3)

FURIN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
biological adhesionGO:00226103310.211
nucleoside catabolic processGO:00091644080.208
cell adhesionGO:00071553250.190
purine ribonucleoside catabolic processGO:00461303980.163
purine nucleotide catabolic processGO:00061954050.161
regulation of cell motilityGO:20001452990.155
Rat
nucleoside triphosphate catabolic processGO:00091433940.152
cell matrix adhesionGO:0007160850.150
ribonucleotide catabolic processGO:00092614050.149
ribonucleoside triphosphate catabolic processGO:00092033910.141
purine nucleoside triphosphate metabolic processGO:00091444120.141
purine nucleoside catabolic processGO:00061523980.140
purine ribonucleoside triphosphate metabolic processGO:00092054110.137
nucleoside triphosphate metabolic processGO:00091414220.131
mapk cascadeGO:00001652880.129
positive regulation of locomotionGO:00400171860.128
Rat
ribonucleoside catabolic processGO:00424544060.128
actin filament based processGO:00300292240.126
cellular component morphogenesisGO:00329893140.125
Worm
small gtpase mediated signal transductionGO:0007264780.124
glycosyl compound catabolic processGO:19016584130.117
ribonucleoside triphosphate metabolic processGO:00091994120.115
regulation of cell migrationGO:00303342890.115
Rat
cell developmentGO:00484683280.114
Worm Fly
purine ribonucleotide catabolic processGO:00091544040.112
nervous system developmentGO:00073992930.111
Worm Fly
endochondral bone morphogenesisGO:006035030.110
cellular amine metabolic processGO:0044106410.102
anterior posterior axis specificationGO:000994820.098
rho protein signal transductionGO:0007266260.097
nucleotide catabolic processGO:00091664080.094
immune responseGO:00069553070.094
regulation of nucleotide catabolic processGO:00308112050.092
purine nucleoside triphosphate catabolic processGO:00091463920.092
establishment of protein localization to membraneGO:00901501210.092
chemotaxisGO:00069351570.090
positive regulation of gtpase activityGO:00435471660.089
protein processingGO:00164852260.087
positive regulation of hydrolase activityGO:00513453310.087
glial cell migrationGO:000834740.087
positive regulation of cellular component movementGO:00512721810.087
Rat
protein maturationGO:00516042330.086
purine containing compound catabolic processGO:00725234110.083
response to oxygen containing compoundGO:19017003690.082
regulation of cellular component movementGO:00512703340.080
Rat
taxisGO:00423301570.077
regulation of locomotionGO:00400123290.077
Rat
regulation of cellular component biogenesisGO:00440872810.076
regulation of cell adhesionGO:00301551660.076
positive regulation of catabolic processGO:00098963100.076
purine ribonucleoside metabolic processGO:00461284370.075
nucleoside phosphate catabolic processGO:19012924120.073
positive regulation of cell proliferationGO:00082843010.072
organophosphate catabolic processGO:00464344300.072
cell cell junction organizationGO:0045216690.071
ras protein signal transductionGO:0007265730.071
cell migration involved in gastrulationGO:004207410.068
locomotory behaviorGO:000762610.068
actin cytoskeleton organizationGO:00300362070.067
single organism cellular localizationGO:19025803320.066
regulation of cell differentiationGO:00455953930.064
cell morphogenesisGO:00009022960.064
Worm
purine ribonucleoside triphosphate catabolic processGO:00092073910.063
positive regulation of purine nucleotide metabolic processGO:19005442270.062
regulation of cellular ketone metabolic processGO:0010565500.062
circulatory system developmentGO:00723592620.062
negative regulation of cellular protein metabolic processGO:00322693530.061
cardiovascular system developmentGO:00723582620.061
vesicle mediated transportGO:00161923710.060
gtp metabolic processGO:00460392390.058
neurogenesisGO:00220081690.057
Worm Fly
response to organic cyclic compoundGO:00140702040.057
signal transduction by phosphorylationGO:00230142970.057
regulation of nucleotide metabolic processGO:00061402690.056
regulation of protein localizationGO:00328802960.056
regulation of cell substrate adhesionGO:0010810680.056
atp metabolic processGO:00460341760.056
endomembrane system organizationGO:00102561960.055
covalent chromatin modificationGO:00165692540.054
regulation of small gtpase mediated signal transductionGO:00510561560.054
ossificationGO:00015031210.054
protein targetingGO:00066051870.054
response to abiotic stimulusGO:00096283360.053
regulation of cellular response to stressGO:00801352440.053
multi organism cellular processGO:00447641560.053
intracellular protein transportGO:00068862700.053
cell junction organizationGO:0034330790.051
tissue morphogenesisGO:0048729960.051
Zebrafish
endochondral ossificationGO:000195810.051
regulation of proteolysisGO:00301622930.051
replacement ossificationGO:003607510.051
nucleoside monophosphate metabolic processGO:00091231910.050
guanosine containing compound catabolic processGO:19010692390.050
positive regulation of cellular catabolic processGO:00313312840.050
purine ribonucleoside monophosphate catabolic processGO:00091691580.049
lipid metabolic processGO:00066293810.049
positive regulation of purine nucleotide catabolic processGO:00331231850.049
post embryonic developmentGO:000979120.049
neuron projection developmentGO:00311751060.049
Worm
regulation of cell matrix adhesionGO:0001952420.049
positive regulation of cell motilityGO:20001471770.049
Rat
cell growthGO:00160491600.048
positive regulation of phosphorylationGO:00423273940.048
cellular response to endogenous stimulusGO:00714953360.048
Rat
cellular response to growth factor stimulusGO:00713631970.047
Rat
regulation of gtp catabolic processGO:00331241800.046
positive regulation of mapk cascadeGO:00434101900.045
regulation of cytokine productionGO:00018172320.045
regulation of ras protein signal transductionGO:00465781550.045
circadian behaviorGO:004851220.045
oocyte differentiationGO:000999420.043
focal adhesion assemblyGO:0048041300.043
regulation of response to external stimulusGO:00321012220.043
guanosine containing compound metabolic processGO:19010682440.043
nucleoside monophosphate catabolic processGO:00091251590.043
cell junction assemblyGO:0034329670.043
inflammatory responseGO:0006954790.043
multicellular organismal agingGO:001025930.042
atp catabolic processGO:00062001570.042
cell morphogenesis involved in differentiationGO:00009041440.042
Worm
negative regulation of cellular component organizationGO:00511292350.042
oogenesisGO:004847720.042
negative regulation of protein metabolic processGO:00512483910.042
positive regulation of protein phosphorylationGO:00019343130.042
hematopoietic or lymphoid organ developmentGO:00485341860.041
cellular ketone metabolic processGO:0042180800.041
protein localization to organelleGO:00333652800.041
ribonucleoside monophosphate catabolic processGO:00091581580.041
adherens junction organizationGO:0034332360.040
response to hormoneGO:00097251750.040
positive regulation of cell migrationGO:00303351720.039
Rat
purine ribonucleoside monophosphate metabolic processGO:00091671860.039
cell substrate adhesionGO:00315891320.039
ameboidal type cell migrationGO:00016671350.039
regulation of adherens junction organizationGO:1903391210.039
female gamete generationGO:000729220.039
regulation of nucleoside metabolic processGO:00091182090.039
regulation of kinase activityGO:00435493140.038
retinal ganglion cell axon guidanceGO:003129020.038
single organism membrane organizationGO:00448022680.038
generation of neuronsGO:00486991520.038
Worm Fly
regulation of neuron differentiationGO:0045664700.037
histone modificationGO:00165702510.037
single organismal cell cell adhesionGO:00163371480.037
regulation of ras gtpase activityGO:00323181280.037
response to cytokineGO:00340972320.036
lipid localizationGO:00108761060.036
purine nucleoside monophosphate catabolic processGO:00091281580.036
cellular amino acid metabolic processGO:00065201160.036
protein localization to membraneGO:00726571600.035
membrane organizationGO:00610242920.035
regulation of cell growthGO:00015581350.035
positive regulation of cellular component organizationGO:00511303760.035
cellular response to external stimulusGO:00714961110.035
regulation of purine nucleotide catabolic processGO:00331212050.035
cell projection organizationGO:00300302520.035
Worm
regulation of cell developmentGO:00602841610.035
activation of immune responseGO:00022531140.035
chondrocyte proliferationGO:003598840.034
response to lipidGO:00339932060.034
cell projection morphogenesisGO:00488581290.034
Worm
regulation of gtpase activityGO:00430871800.034
zymogen activationGO:0031638700.034
regulation of purine nucleotide metabolic processGO:19005422640.034
carbohydrate derivative biosynthetic processGO:19011372070.033
single organism carbohydrate metabolic processGO:00447231930.033
negative regulation of apoptotic processGO:00430663160.033
determination of adult lifespanGO:000834020.033
cell part morphogenesisGO:00329901370.033
Worm
purine nucleoside monophosphate metabolic processGO:00091261860.033
segmentationGO:003528240.032
regulation of focal adhesion assemblyGO:0051893200.032
cellular homeostasisGO:00197251960.032
positive regulation of immune system processGO:00026842830.032
cellular lipid metabolic processGO:00442553030.032
stress activated mapk cascadeGO:0051403930.032
ribonucleoside monophosphate metabolic processGO:00091611870.032
response to hypoxiaGO:0001666960.032
negative regulation of programmed cell deathGO:00430693210.031
rhythmic behaviorGO:000762220.031
system processGO:00030083490.031
positive regulation of nucleotide metabolic processGO:00459812300.031
regulation of cell morphogenesis involved in differentiationGO:0010769830.031
response to other organismGO:00517072610.031
negative regulation of locomotionGO:00400131180.031
blood vessel morphogenesisGO:00485141620.031
tube developmentGO:00352951250.030
regulation of anatomical structure morphogenesisGO:00226032860.030
response to oxidative stressGO:00069791210.030
regulation of stress activated protein kinase signaling cascadeGO:0070302850.030
positive regulation of cell differentiationGO:00455972110.030
craniofacial suture morphogenesisGO:009709430.030
epithelium developmentGO:00604292270.030
organonitrogen compound biosynthetic processGO:19015662000.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
regulation of mapk cascadeGO:00434082620.029
cell activationGO:00017752130.029
stress activated protein kinase signaling cascadeGO:0031098940.029
regulation of cell morphogenesisGO:00226041530.028
positive regulation of transferase activityGO:00513472270.028
negative regulation of catalytic activityGO:00430863350.027
positive regulation of proteolysisGO:00458621420.027
cell substrate adherens junction assemblyGO:0007045300.027
cation transmembrane transportGO:00986552380.027
organelle assemblyGO:00709251760.027
organic anion transportGO:00157111030.027
carbohydrate metabolic processGO:00059752070.026
ion transmembrane transportGO:00342203380.026
chromatin modificationGO:00165682980.026
positive regulation of ras gtpase activityGO:00323201170.026
viral life cycleGO:00190581320.026
cartilage developmentGO:0051216310.026
Zebrafish
response to mechanical stimulusGO:0009612510.026
inorganic cation transmembrane transportGO:00986621940.026
viral processGO:00160321460.026
regulation of peptidase activityGO:00525471800.026
negative regulation of phosphorus metabolic processGO:00105632670.026
leukocyte activationGO:00453211640.026
response to decreased oxygen levelsGO:0036293960.025
embryo developmentGO:00097901230.025
Zebrafish
amine metabolic processGO:0009308440.025
retina layer formationGO:001084230.025
endocytosisGO:00068971590.025
negative regulation of intracellular signal transductionGO:19025321830.025
actin filament organizationGO:00070151280.025
nitrogen compound transportGO:00717051910.025
cell substrate junction assemblyGO:0007044350.025
regulation of apoptotic signaling pathwayGO:20012331750.025
growthGO:00400072020.024
positive regulation of transportGO:00510503360.024
endothelial cell proliferationGO:0001935650.024
single organism cell adhesionGO:00986021790.024
metal ion transportGO:00300012720.024
regulation of synaptic plasticityGO:004816730.024
regulation of protein kinase activityGO:00458592890.024
nuclear transportGO:00511691790.024
response to oxygen levelsGO:00704821000.023
syncytium formation by plasma membrane fusionGO:000076820.023
establishment of nucleus localizationGO:004002310.023
regulation of cell projection organizationGO:00313441070.023
negative regulation of cell proliferationGO:00082852280.023
regulation of cellular amine metabolic processGO:0033238110.023
negative regulation of phosphate metabolic processGO:00459362670.023
response to growth factorGO:00708482050.023
Rat
protein catabolic processGO:00301633250.023
positive regulation of cell growthGO:0030307480.023
positive regulation of protein transportGO:00512221350.023
positive regulation of cytokine productionGO:00018191670.023
spermatid differentiationGO:004851540.023
positive regulation of intracellular protein transportGO:0090316760.023
cytokine productionGO:00018162470.023
i kappab kinase nf kappab signalingGO:00072491660.022
neuron differentiationGO:00301821380.022
Worm Fly
epithelial cell proliferationGO:00506731280.022
blood vessel developmentGO:00015681720.022
positive regulation of kinase activityGO:00336742040.022
regulation of sequence specific dna binding transcription factor activityGO:00510902110.022
positive regulation of apoptotic processGO:00430652460.022
inorganic ion transmembrane transportGO:00986602310.022
single organism reproductive processGO:0044702980.022
organ formationGO:004864530.022
bone mineralizationGO:0030282340.022
memoryGO:000761330.022
dephosphorylationGO:00163112090.022
cell chemotaxisGO:00603261120.022
connective tissue developmentGO:0061448390.021
Zebrafish
mitochondrion organizationGO:00070051560.021
plasma membrane organizationGO:00070091150.021
hemopoiesisGO:00300971800.021
heart developmentGO:0007507950.021
establishment or maintenance of cell polarityGO:0007163310.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
regulation of axon guidanceGO:190266730.021
maintenance of locationGO:00512351120.021
cellular response to abiotic stimulusGO:00712141170.021
positive regulation of nucleoside metabolic processGO:00459791860.021
tissue migrationGO:00901301190.021
divalent metal ion transportGO:00708381520.021
regulation of cell substrate junction assemblyGO:0090109200.020
spermatid developmentGO:000728640.020
digestive tract developmentGO:0048565750.020
positive regulation of nucleotide catabolic processGO:00308131850.020
oocyte developmentGO:004859910.020
regulation of cell junction assemblyGO:1901888290.020
regulation of growthGO:00400081650.020
cation transportGO:00068123310.020
chromatin organizationGO:00063253510.020
apoptotic signaling pathwayGO:00971902680.020
regulation of rho protein signal transductionGO:0035023790.020
embryonic morphogenesisGO:0048598850.020
Zebrafish
transmembrane transportGO:00550853990.020
negative regulation of cell deathGO:00605483450.020
osteoblast differentiationGO:0001649920.020
cytoplasmic transportGO:00164823790.020
posttranscriptional regulation of gene expressionGO:00106082130.019
neuromuscular junction developmentGO:000752830.019
positive regulation of immune responseGO:00507781590.019
regulation of vesicle mediated transportGO:00606271300.019
regulation of protein targetingGO:1903533910.019
cellular response to organic cyclic compoundGO:00714071270.019
nucleus localizationGO:005164710.019
positive regulation of organelle organizationGO:00106381950.019
positive regulation of gtp catabolic processGO:00331261660.019
regulation of defense responseGO:00313471540.019
regulation of cellular amino acid metabolic processGO:000652160.019
circulatory system processGO:00030131130.019
convergent extension involved in gastrulationGO:006002710.019
negative regulation of proteolysisGO:00458611320.019
cellular chemical homeostasisGO:00550821800.019
lipid biosynthetic processGO:00086101770.019
regulation of protein maturationGO:19033171500.019
establishment of protein localization to organelleGO:00725941720.019
organophosphate biosynthetic processGO:00904071630.019
secretion by cellGO:00329402260.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
Rat
regulation of anatomical structure sizeGO:00900661010.019
multi organism membrane organizationGO:0044803120.019
anion transportGO:00068201610.018
positive regulation of developmental processGO:00510943140.018
regulation of transferase activityGO:00513383550.018
regulation of neurogenesisGO:0050767820.018
regulation of intracellular transportGO:00323861950.018
positive regulation of protein kinase activityGO:00458601900.018
epithelium migrationGO:00901321190.018
secretionGO:00469032540.018
anterior posterior axis specification embryoGO:000859520.018
positive regulation of intracellular transportGO:00323881040.018
response to metal ionGO:0010038840.018
digestive system developmentGO:0055123750.018
adult locomotory behaviorGO:000834410.018
neurological system processGO:00508771630.018
jnk cascadeGO:0007254800.018
response to biotic stimulusGO:00096072760.017
negative regulation of protein phosphorylationGO:00019331400.017
negative regulation of hydrolase activityGO:00513461820.017
protein autophosphorylationGO:00467771230.017
regulation of phosphatase activityGO:0010921810.017
glycerolipid metabolic processGO:00464861070.017
regulation of rho gtpase activityGO:0032319660.017
positive regulation of cell deathGO:00109422630.017
regulation of protein transportGO:00512232130.017
negative regulation of cellular component movementGO:00512711060.017
regulation of cellular response to growth factor stimulusGO:0090287760.017
Rat
semaphorin plexin signaling pathwayGO:007152640.017
limbic system developmentGO:002176130.017
blastoderm segmentationGO:000735020.017
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.017
axonogenesisGO:0007409310.017
tripartite regional subdivisionGO:000735120.017
cell fate determinationGO:000170930.016
microtubule based processGO:00070172100.016
motor neuron axon guidanceGO:000804520.016
regulation of protein catabolic processGO:00421761550.016
regulation of dephosphorylationGO:0035303960.016
regulation of cell cell adhesionGO:0022407570.016
leukocyte differentiationGO:0002521980.016
negative regulation of cell motilityGO:20001461040.016
autophagyGO:0006914880.016
organ morphogenesisGO:00098871470.016
Zebrafish
cellular protein complex assemblyGO:00436231880.016
immune system developmentGO:00025201950.016
neuron projection morphogenesisGO:0048812500.016
Worm
negative regulation of multi organism processGO:0043901920.016
defense responseGO:00069523150.016
divalent inorganic cation transportGO:00725111580.016
extrinsic apoptotic signaling pathwayGO:00971911190.016
reproductive processGO:00224141060.016
ion homeostasisGO:00508012300.016
regulation of nervous system developmentGO:0051960880.016
regulation of cytoskeleton organizationGO:00514931770.015
regulation of multi organism processGO:00439001570.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of mitotic cell cycleGO:00073461890.015
nuclear migrationGO:000709710.015
reproductive system developmentGO:0061458560.015
cellular macromolecular complex assemblyGO:00346223240.015
regulation of jnk cascadeGO:0046328730.015
regulation of cell cycle processGO:00105642660.015
epithelial cell migrationGO:00106311190.015
negative regulation of protein processingGO:00109551420.015
establishment of protein localization to plasma membraneGO:0090002680.015
nucleocytoplasmic transportGO:00069131760.015
drinking behaviorGO:004275610.015
golgi vesicle transportGO:0048193800.015
innate immune responseGO:00450871780.015
positive regulation of cellular amine metabolic processGO:003324070.015
protein localization to plasma membraneGO:0072659930.015
compound eye developmentGO:004874910.015
branching morphogenesis of an epithelial tubeGO:0048754190.015
myeloid cell differentiationGO:00300991170.015
peripheral nervous system developmentGO:000742220.015
central nervous system developmentGO:00074171230.014
myosin filament assemblyGO:003103420.014
morphogenesis of a branching structureGO:0001763210.014
regulation of meiotic cell cycleGO:005144540.014
regulation of inflammatory responseGO:0050727460.014
organic acid transportGO:0015849650.014
rab protein signal transductionGO:003248240.014
carboxylic acid transportGO:0046942630.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
positive regulation of peptidase activityGO:0010952880.014
response to inorganic substanceGO:00100351270.014
organic acid biosynthetic processGO:0016053970.014
wound healingGO:00420601150.014
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.014
response to woundingGO:00096111680.014
vasculature developmentGO:00019441810.014
nucleotide biosynthetic processGO:00091651090.014
response to extracellular stimulusGO:0009991850.014
regulation of protein localization to nucleusGO:1900180850.014
neuron developmentGO:00486661130.014
Worm Fly
regulation of neuron projection developmentGO:0010975570.014
regulation of cell activationGO:00508651250.014
regulation of bindingGO:00510981110.014
blood circulationGO:00080151130.014
glycoprotein metabolic processGO:00091001100.014
mitotic cell cycle processGO:19030472860.014
regulation of immune responseGO:00507762010.014
response to estrogenGO:0043627470.014
regulation of endopeptidase activityGO:00525481700.013
regulation of intracellular protein transportGO:00331571230.013
angiogenesis involved in wound healingGO:006005540.013
peptidyl serine modificationGO:00182091060.013
nuclear importGO:00511701060.013
ribose phosphate biosynthetic processGO:0046390820.013
nucleoside phosphate biosynthetic processGO:19012931090.013
small molecule biosynthetic processGO:00442831570.013
protein importGO:00170381300.013
angiogenesisGO:00015251470.013
chemical homeostasisGO:00488783060.013
regulation of secretion by cellGO:19035301770.013
stem cell divisionGO:001714520.013
lipid modificationGO:0030258840.013
lipid transportGO:0006869900.013
gtp catabolic processGO:00061842370.013
negative regulation of phosphorylationGO:00423261740.013
melanin metabolic processGO:000658210.013
negative regulation of dephosphorylationGO:0035305630.013
internal peptidyl lysine acetylationGO:0018393970.013
myoblast fusionGO:000752010.013
regulation of stress activated mapk cascadeGO:0032872840.013
positive regulation of growthGO:0045927580.013
cellular response to dna damage stimulusGO:00069743790.013
striated muscle myosin thick filament assemblyGO:007168820.013
positive regulation of vascular endothelial growth factor signaling pathwayGO:190074830.013
reactive nitrogen species metabolic processGO:200105730.013
regulation of establishment of protein localizationGO:00702012420.013
epithelial cell differentiationGO:00308551410.012
response to external biotic stimulusGO:00432072610.012
negative regulation of peptidase activityGO:0010466910.012
regulation of response to woundingGO:19030341010.012
embryonic placenta developmentGO:000189210.012
positive regulation of programmed cell deathGO:00430682490.012
protein localization to nucleusGO:00345041360.012
response to molecule of bacterial originGO:0002237820.012
organelle localizationGO:0051640840.012
t cell activationGO:0042110990.012
leukocyte migrationGO:00509001070.012
cadmium ion transportGO:001569120.012
regenerationGO:003109940.012
carboxylic acid biosynthetic processGO:0046394970.012
skeletal system developmentGO:0001501790.012
Zebrafish
regulation of cellular component sizeGO:0032535820.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
associative learningGO:000830610.012
immune effector processGO:00022521590.012
negative regulation of endopeptidase activityGO:0010951840.012
response to nitrogen compoundGO:19016981840.012
pattern specification processGO:0007389430.012
sleepGO:003043120.012
single organism nuclear importGO:19025931040.012
membrane fusion involved in viral entry into host cellGO:003966330.012
negative regulation of transferase activityGO:00513481240.012
cellular response to lipidGO:00713961270.012
negative regulation of cell cycleGO:00457861930.012
gastrulationGO:0007369510.011
t cell differentiation in thymusGO:003307740.011
negative regulation of protein maturationGO:19033181420.011
morphogenesis of a polarized epitheliumGO:000173830.011
regulation of cell cycleGO:00517263930.011
cellular response to transforming growth factor beta stimulusGO:0071560940.011
Rat
peptidyl tyrosine phosphorylationGO:00181081700.011

FURIN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.028
inherited metabolic disorderDOID:6552420.028
immune system diseaseDOID:29141550.023
disease of cellular proliferationDOID:145661740.022
organ system cancerDOID:00506861640.022
cancerDOID:1621670.022
musculoskeletal system diseaseDOID:172230.017
central nervous system diseaseDOID:3311860.016
nervous system diseaseDOID:8634310.016
cardiovascular system diseaseDOID:12871060.013