Homo sapiens

45 known processes

CNOT8

CCR4-NOT transcription complex, subunit 8

(Aliases: POP2,CALIF,hCAF1,CAF1)

CNOT8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015380.999
Human
fibroblast apoptotic processGO:004434680.996
mrna 3 end processingGO:0031124240.988
Human Fly
positive regulation of mrna catabolic processGO:0061014100.986
Human
regulation of cytoplasmic mrna processing body assemblyGO:001060350.985
positive regulation of mrna 3 end processingGO:0031442120.966
Human
rna catabolic processGO:0006401710.960
regulation of stem cell maintenanceGO:200003640.955
positive regulation of fibroblast apoptotic processGO:200027160.941
nuclear transcribed mrna poly a tail shorteningGO:000028980.941
Human Fly
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021180.939
Human
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021380.936
Human
rna 3 end processingGO:0031123350.921
Human Fly
mrna catabolic processGO:0006402560.916
rna phosphodiester bond hydrolysisGO:0090501350.896
nuclear transcribed mrna catabolic process exonucleolyticGO:000029170.878
translationGO:00064121320.852
Fly
rna processingGO:00063962550.848
Human Fly
nuclear transcribed mrna catabolic processGO:0000956480.839
regulation of mrna 3 end processingGO:0031440120.811
Human
cytoplasmic mrna processing body assemblyGO:0033962100.810
positive regulation of dna templated transcription elongationGO:0032786180.807
positive regulation of catabolic processGO:00098963100.785
Human
positive regulation of mrna processingGO:0050685170.750
Human
regulation of endothelial cell differentiationGO:004560140.738
regulation of mitotic cell cycleGO:00073461890.734
Worm Fly
cellular macromolecular complex assemblyGO:00346223240.716
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.705
negative regulation of protein metabolic processGO:00512483910.701
Fly
mrna processingGO:00063971330.676
Human Fly
positive regulation of mrna metabolic processGO:1903313190.643
Human
positive regulation of ligand dependent nuclear receptor transcription coactivator activityGO:200032720.637
post embryonic developmentGO:000979120.603
Worm
mrna metabolic processGO:00160711750.601
regulation of cell cycleGO:00517263930.599
Worm Fly
nucleic acid phosphodiester bond hydrolysisGO:00903051020.590
positive regulation of organelle assemblyGO:1902117170.554
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.546
stem cell developmentGO:0048864690.540
negative regulation of cellular protein metabolic processGO:00322693530.531
Fly
ribonucleoprotein complex subunit organizationGO:0071826810.527
ribonucleoprotein complex assemblyGO:0022618780.510
regulation of translationGO:0006417890.506
Fly
determination of adult lifespanGO:000834020.503
cellular macromolecule catabolic processGO:00442653800.482
regulation of cell cycle processGO:00105642660.467
Fly
protein methylationGO:0006479740.465
positive regulation of endothelial cell differentiationGO:004560320.453
positive regulation of myoblast differentiationGO:004566360.441
nuclear transcribed mrna catabolic process no go decayGO:007096620.429
cell developmentGO:00484683280.424
Fly
mitotic cell cycle phase transitionGO:00447721620.420
Fly
regulation of mrna catabolic processGO:0061013130.402
Human
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.394
regulation of mrna metabolic processGO:1903311530.389
Human
mitotic dna damage checkpointGO:0044773280.387
Fly
regulation of mitotic cell cycle phase transitionGO:19019901180.381
Fly
regulation of cell developmentGO:00602841610.377
regulation of cell differentiationGO:00455953930.374
posttranscriptional regulation of gene expressionGO:00106082130.372
Fly
rna phosphodiester bond hydrolysis exonucleolyticGO:0090503140.367
regulation of dna templated transcription elongationGO:0032784230.361
negative regulation of translationGO:0017148370.359
Fly
regulation of organelle assemblyGO:1902115400.352
anatomical structure formation involved in morphogenesisGO:00486462840.334
positive regulation of cellular catabolic processGO:00313312840.333
Human
negative regulation of cell differentiationGO:00455961710.319
ribonucleoprotein complex biogenesisGO:00226131160.315
positive regulation of cytoplasmic mrna processing body assemblyGO:001060640.314
multicellular organismal agingGO:001025930.310
transcription elongation from rna polymerase ii promoterGO:0006368180.298
dna integrity checkpointGO:0031570710.293
Fly
positive regulation of developmental processGO:00510943140.273
mitotic dna integrity checkpointGO:0044774300.256
Fly
negative regulation of cell cycleGO:00457861930.255
Worm Fly
organelle assemblyGO:00709251760.255
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.251
protein modification by small protein conjugationGO:00324463420.241
regulation of stem cell differentiationGO:2000736560.239
muscle cell developmentGO:0055001290.233
macromolecule methylationGO:0043414970.229
stem cell maintenanceGO:0019827190.216
regulation of transcription elongation from rna polymerase ii promoterGO:0034243130.198
regulation of cell cycle g1 s phase transitionGO:1902806420.196
positive regulation of cell differentiationGO:00455972110.195
positive regulation of cellular component organizationGO:00511303760.194
g1 s transition of mitotic cell cycleGO:0000082780.192
positive regulation of organelle organizationGO:00106381950.191
epithelial cell differentiationGO:00308551410.188
regulation of fibroblast apoptotic processGO:200026980.187
regulation of cellular component biogenesisGO:00440872810.185
regulation of striated muscle tissue developmentGO:0016202260.183
rab protein signal transductionGO:003248240.182
nervous system developmentGO:00073992930.166
Fly
trophectodermal cell differentiationGO:000182930.163
myoblast differentiationGO:0045445210.156
mitotic cell cycle processGO:19030472860.151
Fly
intracellular receptor signaling pathwayGO:00305221040.147
striated muscle cell differentiationGO:0051146430.146
intracellular estrogen receptor signaling pathwayGO:0030520230.140
system processGO:00030083490.138
blastocyst developmentGO:000182430.136
positive regulation of epithelial cell differentiationGO:0030858140.134
intracellular steroid hormone receptor signaling pathwayGO:0030518610.133
negative regulation of developmental processGO:00510932470.128
negative regulation of dna metabolic processGO:0051053570.128
oogenesisGO:004847720.125
generation of neuronsGO:00486991520.120
Fly
mitotic cell cycle checkpointGO:0007093680.118
Fly
negative regulation of intracellular steroid hormone receptor signaling pathwayGO:0033144180.118
g2 dna damage checkpointGO:0031572260.115
Fly
blood vessel morphogenesisGO:00485141620.111
endothelial cell differentiationGO:0045446260.110
regulation of anatomical structure morphogenesisGO:00226032860.110
positive regulation of cellular component biogenesisGO:00440891580.110
dna templated transcription elongationGO:0006354250.109
positive regulation of cell deathGO:00109422630.109
regulation of myoblast differentiationGO:0045661120.108
growthGO:00400072020.108
regulation of g1 s transition of mitotic cell cycleGO:2000045400.106
epithelium developmentGO:00604292270.106
small gtpase mediated signal transductionGO:0007264780.106
ribonucleoside triphosphate catabolic processGO:00092033910.106
angiogenesisGO:00015251470.104
negative regulation of cell cycle processGO:00109481210.103
Fly
organelle localizationGO:0051640840.103
cell projection organizationGO:00300302520.102
neurogenesisGO:00220081690.101
Fly
muscle organ developmentGO:0007517560.100
Fly
regulation of intracellular estrogen receptor signaling pathwayGO:0033146130.099
neuron differentiationGO:00301821380.094
Fly
positive regulation of cell cycle processGO:00900681060.094
purine ribonucleoside triphosphate metabolic processGO:00092054110.091
regulation of growthGO:00400081650.090
methylationGO:00322591060.088
myotube cell developmentGO:0014904140.085
vesicle mediated transportGO:00161923710.084
Worm
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314770.084
positive regulation of muscle cell differentiationGO:0051149150.084
protein alkylationGO:0008213740.083
regulation of muscle organ developmentGO:0048634270.083
embryo developmentGO:00097901230.082
Worm
single organism reproductive processGO:0044702980.082
Worm
skeletal muscle fiber developmentGO:0048741120.082
cardiovascular system developmentGO:00723582620.080
ribonucleotide catabolic processGO:00092614050.080
dna damage checkpointGO:0000077680.079
Fly
positive regulation of cell proliferationGO:00082843010.077
cellular protein complex assemblyGO:00436231880.076
vasculature developmentGO:00019441810.076
negative regulation of cell proliferationGO:00082852280.076
Human
circulatory system developmentGO:00723592620.075
regulation of myotube differentiationGO:0010830180.074
neuron projection developmentGO:00311751060.074
blood vessel developmentGO:00015681720.073
regulation of neural precursor cell proliferationGO:200017740.072
cell cycle phase transitionGO:00447701730.072
Fly
mitotic cell cycleGO:00002783260.072
Worm Fly
regulation of ligand dependent nuclear receptor transcription coactivator activityGO:200032530.071
regulation of cell cycle phase transitionGO:19019871260.071
Fly
endothelium developmentGO:0003158330.071
positive regulation of angiogenesisGO:0045766510.070
cell growthGO:00160491600.069
cell type specific apoptotic processGO:00972851250.067
cell cycle checkpointGO:00000751170.067
Fly
guanosine containing compound metabolic processGO:19010682440.066
regulation of nucleotide metabolic processGO:00061402690.065
regulation of muscle tissue developmentGO:1901861260.063
sex differentiationGO:0007548450.060
Worm
negative regulation of cellular component organizationGO:00511292350.060
cellular amine metabolic processGO:0044106410.060
female gamete generationGO:000729220.059
purine nucleoside triphosphate catabolic processGO:00091463920.059
purine ribonucleoside triphosphate catabolic processGO:00092073910.059
reproductionGO:0000003630.059
Worm
response to oxygen containing compoundGO:19017003690.059
cellular response to dna damage stimulusGO:00069743790.058
Fly
muscle cell differentiationGO:0042692630.056
stem cell differentiationGO:0048863930.056
regulation of cellular amine metabolic processGO:0033238110.055
ribonucleoside triphosphate metabolic processGO:00091994120.055
neuron developmentGO:00486661130.055
Fly
regulation of striated muscle cell differentiationGO:0051153250.053
regulation of skeletal muscle fiber developmentGO:0048742120.052
positive regulation of apoptotic processGO:00430652460.051
negative regulation of phosphate metabolic processGO:00459362670.050
gtp metabolic processGO:00460392390.050
response to oxidative stressGO:00069791210.050
reproductive structure developmentGO:0048608550.048
Worm
regulation of angiogenesisGO:0045765920.048
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015180.048
Human
single organism cellular localizationGO:19025803320.046
regulation of transferase activityGO:00513383550.046
purine ribonucleoside catabolic processGO:00461303980.045
maintenance of locationGO:00512351120.045
negative regulation of retinoic acid receptor signaling pathwayGO:004838740.045
nucleoside catabolic processGO:00091644080.044
meiotic cell cycleGO:0051321130.044
Worm
positive regulation of transportGO:00510503360.043
purine nucleotide catabolic processGO:00061954050.042
nucleoside phosphate catabolic processGO:19012924120.041
blastocyst formationGO:000182530.040
response to starvationGO:0042594590.040
lipid localizationGO:00108761060.039
response to abiotic stimulusGO:00096283360.038
glycosyl compound catabolic processGO:19016584130.036
negative regulation of mitotic cell cycleGO:00459301020.036
Worm Fly
purine nucleoside triphosphate metabolic processGO:00091444120.036
negative regulation of cell deathGO:00605483450.036
establishment of organelle localizationGO:0051656590.036
striated muscle tissue developmentGO:0014706590.036
regulation of vasculature developmentGO:1901342970.036
histone modificationGO:00165702510.035
dna replicationGO:00062601160.035
positive regulation of gtp catabolic processGO:00331261660.035
negative regulation of mitotic cell cycle phase transitionGO:1901991850.035
Fly
regulation of gtp catabolic processGO:00331241800.035
negative regulation of immune system processGO:00026831360.034
regulation of purine nucleotide metabolic processGO:19005422640.033
spindle organizationGO:0007051530.033
negative regulation of phosphorus metabolic processGO:00105632670.033
dna repairGO:00062811980.033
development of primary sexual characteristicsGO:0045137350.033
Worm
positive regulation of hydrolase activityGO:00513453310.033
response to peptideGO:1901652650.032
organophosphate catabolic processGO:00464344300.032
negative regulation of catalytic activityGO:00430863350.032
membrane organizationGO:00610242920.032
nucleotide catabolic processGO:00091664080.031
vesicle organizationGO:0016050620.030
carbohydrate derivative biosynthetic processGO:19011372070.030
positive regulation of programmed cell deathGO:00430682490.030
guanosine containing compound catabolic processGO:19010692390.030
negative regulation of apoptotic processGO:00430663160.030
small molecule biosynthetic processGO:00442831570.030
meiosis iGO:000712740.029
regulation of nucleotide catabolic processGO:00308112050.029
regulation of epithelial cell differentiationGO:0030856240.029
response to fungusGO:000962040.029
cellular ketone metabolic processGO:0042180800.029
regulation of skeletal muscle tissue developmentGO:0048641150.029
response to nutrient levelsGO:0031667810.028
regulation of mrna processingGO:0050684480.028
Human
microtubule cytoskeleton organizationGO:00002261760.028
negative regulation of dna replicationGO:0008156290.028
ribonucleoside catabolic processGO:00424544060.027
regulation of kinase activityGO:00435493140.027
striated muscle cell developmentGO:0055002270.027
reproductive processGO:00224141060.027
Worm
negative regulation of organelle organizationGO:00106391260.027
cellular amino acid metabolic processGO:00065201160.027
regulation of ras gtpase activityGO:00323181280.026
amine metabolic processGO:0009308440.026
positive regulation of gtpase activityGO:00435471660.026
nuclear divisionGO:00002801280.025
response to extracellular stimulusGO:0009991850.025
positive regulation of ras gtpase activityGO:00323201170.025
neuromuscular junction developmentGO:000752830.024
negative regulation of cell cycle phase transitionGO:1901988890.024
Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.024
muscle fiber developmentGO:0048747160.024
response to hormoneGO:00097251750.024
regulation of meiotic cell cycleGO:005144540.024
Worm
regulation of dna replicationGO:0006275680.024
myotube differentiationGO:0014902220.024
tissue migrationGO:00901301190.023
gonad developmentGO:0008406340.023
Worm
intracellular protein transportGO:00068862700.023
mitotic g2 dna damage checkpointGO:000709570.023
Fly
regulation of gtpase activityGO:00430871800.023
endocytosisGO:00068971590.023
Worm
forebrain developmentGO:0030900260.023
negative regulation of protein complex assemblyGO:0031333430.023
neuron deathGO:0070997650.023
muscle tissue developmentGO:0060537620.023
purine containing compound catabolic processGO:00725234110.022
central nervous system developmentGO:00074171230.022
positive regulation of mitotic cell cycleGO:0045931600.022
regulation of retinoic acid receptor signaling pathwayGO:004838590.022
histone ubiquitinationGO:0016574310.022
oocyte developmentGO:004859910.022
regulation of protein maturationGO:19033171500.022
regulation of cellular amino acid metabolic processGO:000652160.022
rho protein signal transductionGO:0007266260.022
positive regulation of cell cycleGO:00457871400.021
Worm
skeletal muscle organ developmentGO:0060538260.021
internal peptidyl lysine acetylationGO:0018393970.021
regulation of cellular ketone metabolic processGO:0010565500.021
organelle fissionGO:00482851490.021
response to virusGO:00096151260.021
regulation of muscle cell differentiationGO:0051147310.021
negative regulation of growthGO:0045926970.020
regulation of meiosisGO:004002030.020
developmental process involved in reproductionGO:0003006660.020
Worm
mapk cascadeGO:00001652880.020
negative regulation of protein modification processGO:00314002000.020
multicellular organism reproductionGO:0032504420.020
positive regulation of nucleoside metabolic processGO:00459791860.020
covalent chromatin modificationGO:00165692540.019
positive regulation of nucleotide metabolic processGO:00459812300.019
actin filament based processGO:00300292240.019
cell cycle g1 s phase transitionGO:0044843800.019
protein targetingGO:00066051870.019
response to organonitrogen compoundGO:00102431560.019
nucleoside triphosphate catabolic processGO:00091433940.019
negative regulation of cellular amine metabolic processGO:003323930.019
organonitrogen compound biosynthetic processGO:19015662000.018
negative regulation of transferase activityGO:00513481240.018
associative learningGO:000830610.018
retrograde transport endosome to golgiGO:0042147450.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
protein localization to organelleGO:00333652800.018
anion transportGO:00068201610.018
regulation of purine nucleotide catabolic processGO:00331212050.018
protein maturationGO:00516042330.018
purine nucleoside monophosphate catabolic processGO:00091281580.017
camp metabolic processGO:0046058610.017
cytoplasmic transportGO:00164823790.017
cell divisionGO:00513011680.017
positive regulation of dendrite morphogenesisGO:005077530.017
golgi vesicle transportGO:0048193800.017
gtp catabolic processGO:00061842370.017
negative regulation of neural precursor cell proliferationGO:200017810.017
regulation of ras protein signal transductionGO:00465781550.017
nucleoside triphosphate metabolic processGO:00091414220.017
response to mechanical stimulusGO:0009612510.017
signal transduction by phosphorylationGO:00230142970.017
positive regulation of nucleotide catabolic processGO:00308131850.017
cell cell signalingGO:00072671550.017
negative regulation of hydrolase activityGO:00513461820.016
response to peptide hormoneGO:0043434610.016
regulation of anatomical structure sizeGO:00900661010.016
actin cytoskeleton organizationGO:00300362070.016
single organism carbohydrate metabolic processGO:00447231930.016
negative regulation of synaptic transmissionGO:005080520.016
cytokine productionGO:00018162470.016
neurotransmitter secretionGO:000726940.016
memoryGO:000761330.015
response to external biotic stimulusGO:00432072610.015
negative regulation of phosphorylationGO:00423261740.015
peptidyl lysine modificationGO:00182051440.015
purine ribonucleoside metabolic processGO:00461284370.015
meiotic chromosome segregationGO:004513240.015
anterior posterior axis specificationGO:000994820.015
regulation of protein kinase activityGO:00458592890.015
plasma membrane organizationGO:00070091150.015
regulation of regulatory t cell differentiationGO:004558940.015
golgi vesicle fusion to target membraneGO:004821020.015
regulation of response to external stimulusGO:00321012220.015
stem cell divisionGO:001714520.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
retinoic acid receptor signaling pathwayGO:0048384130.014
regulation of protein localizationGO:00328802960.014
cellular lipid metabolic processGO:00442553030.014
peptidyl lysine acetylationGO:00183941010.014
multicellular organismal reproductive processGO:0048609400.014
central nervous system neuron axonogenesisGO:002195530.014
muscle structure developmentGO:0061061980.014
Fly
protein dealkylationGO:0008214170.014
endomembrane system organizationGO:00102561960.014
chromatin modificationGO:00165682980.014
positive regulation of phosphorylationGO:00423273940.014
organic acid biosynthetic processGO:0016053970.014
negative regulation of protein kinase activityGO:0006469980.014
organophosphate biosynthetic processGO:00904071630.014
receptor mediated endocytosisGO:0006898840.014
Worm
cellular homeostasisGO:00197251960.014
negative regulation of neuron deathGO:1901215320.014
spermatid developmentGO:000728640.014
engulfment of apoptotic cellGO:004365220.013
skeletal muscle tissue developmentGO:0007519240.013
positive regulation of cellular amine metabolic processGO:003324070.013
alcohol metabolic processGO:00060661140.013
behavioral response to ethanolGO:004814920.013
regulation of cytokine productionGO:00018172320.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.013
carboxylic acid biosynthetic processGO:0046394970.013
macromolecule glycosylationGO:0043413630.013
spermatid differentiationGO:004851540.013
protein complex disassemblyGO:0043241520.013
mitotic g2 m transition checkpointGO:004481890.013
Fly
regulation of chromosome organizationGO:00330441030.013
regulation of actin filament based processGO:00329701410.012
inner ear morphogenesisGO:004247240.012
glycosylationGO:0070085710.012
oocyte differentiationGO:000999420.012
internal protein amino acid acetylationGO:00064751010.012
regulation of cyclic nucleotide metabolic processGO:0030799630.012
neuron apoptotic processGO:0051402390.012
rna splicingGO:00083801310.012
lung saccule developmentGO:006043020.012
negative regulation of kinase activityGO:00336731060.012
purine nucleoside catabolic processGO:00061523980.012
positive regulation of mitotic cell cycle phase transitionGO:1901992190.012
morphogenesis of embryonic epitheliumGO:001633140.012
regulation of immune responseGO:00507762010.012
locomotory behaviorGO:000762610.012
ribonucleotide biosynthetic processGO:0009260810.012
response to electrical stimulusGO:005160210.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
regulation of cell morphogenesisGO:00226041530.012
single organism membrane organizationGO:00448022680.012
regulation of vesicle mediated transportGO:00606271300.011
hippocampus developmentGO:002176610.011
immune responseGO:00069553070.011
cellular chemical homeostasisGO:00550821800.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
regulation of intracellular protein transportGO:00331571230.011
dendritic spine morphogenesisGO:006099730.011
nucleoside monophosphate metabolic processGO:00091231910.011
glycoprotein metabolic processGO:00091001100.011
cell part morphogenesisGO:00329901370.011
positive regulation of cytokine productionGO:00018191670.011
defense response to fungusGO:005083240.011
negative regulation of intracellular signal transductionGO:19025321830.011
regulation of cellular response to stressGO:00801352440.011
lymphocyte activationGO:00466491330.011
atp metabolic processGO:00460341760.011
spermatogenesisGO:0007283220.011
secretionGO:00469032540.011
regulation of dna metabolic processGO:00510521530.011
cellular component disassemblyGO:0022411920.011
response to nitrogen compoundGO:19016981840.011
establishment of spindle localizationGO:0051293120.011
regulation of cytoskeleton organizationGO:00514931770.011
male gamete generationGO:0048232220.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
oxidation reduction processGO:00551143960.011
regulation of protein transportGO:00512232130.011
positive regulation of leukocyte activationGO:0002696800.011
cell fate commitment involved in pattern specificationGO:006058110.011
deadenylation dependent decapping of nuclear transcribed mrnaGO:000029010.011
ras protein signal transductionGO:0007265730.011
regulation of cell divisionGO:00513021160.011
histone acetylationGO:0016573930.011
sexual reproductionGO:0019953370.011
segmentationGO:003528240.011
regulation of rab protein signal transductionGO:0032483390.010
reactive oxygen species metabolic processGO:0072593750.010
protein demethylationGO:0006482170.010
negative regulation of protein processingGO:00109551420.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
protein localization to plasma membraneGO:0072659930.010
reproductive system developmentGO:0061458560.010
Worm
protein processingGO:00164852260.010
biological adhesionGO:00226103310.010
blastoderm segmentationGO:000735020.010
negative regulation of multicellular organismal processGO:00512413170.010
sensory perceptionGO:00076001030.010
behaviorGO:00076101120.010

CNOT8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.015
disease of cellular proliferationDOID:145661740.015
immune system diseaseDOID:29141550.012
anemiaDOID:2355550.012
hematopoietic system diseaseDOID:741000.012