Homo sapiens

166 known processes

AIF1

allograft inflammatory factor 1

(Aliases: IRT1,IBA1,AIF-1,IRT-1)

AIF1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell activationGO:00017752130.283
regulation of myeloid leukocyte mediated immunityGO:000288640.283
regulation of leukocyte proliferationGO:0070663670.251
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.229
regulation of lymphocyte proliferationGO:0050670640.219
leukocyte proliferationGO:0070661740.198
regulation of mononuclear cell proliferationGO:0032944650.195
regulation of t cell proliferationGO:0042129420.193
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.192
cell developmentGO:00484683280.190
regulation of immune responseGO:00507762010.175
positive regulation of developmental processGO:00510943140.171
t cell activationGO:0042110990.163
serotonin secretionGO:000182010.156
mononuclear cell proliferationGO:0032943710.156
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.145
membrane organizationGO:00610242920.138
Mouse
positive regulation of hydrolase activityGO:00513453310.115
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988640.113
positive regulation of immune responseGO:00507781590.106
negative regulation of immune system processGO:00026831360.097
negative regulation of interferon beta secretionGO:003554810.094
endomembrane system organizationGO:00102561960.089
innate immune responseGO:00450871780.085
positive regulation of cell differentiationGO:00455972110.084
cellular lipid metabolic processGO:00442553030.083
lymphocyte proliferationGO:0046651700.082
cytokine productionGO:00018162470.078
plasma membrane organizationGO:00070091150.078
myeloid leukocyte migrationGO:0097529620.075
lymphocyte activationGO:00466491330.074
endocytosisGO:00068971590.072
Mouse
positive regulation of transportGO:00510503360.071
leukocyte activationGO:00453211640.071
cellular ketone metabolic processGO:0042180800.070
positive regulation of cell deathGO:00109422630.069
regulation of cell activationGO:00508651250.066
regulation of cellular ketone metabolic processGO:0010565500.066
immune effector processGO:00022521590.064
regulation of vesicle mediated transportGO:00606271300.061
exocytosisGO:0006887710.061
actin filament based processGO:00300292240.061
regulation of secretion by cellGO:19035301770.060
regulation of protein transportGO:00512232130.059
regulation of cell migrationGO:00303342890.056
response to oxygen containing compoundGO:19017003690.056
Rat
granulocyte migrationGO:0097530400.055
regulation of multi organism processGO:00439001570.054
regulation of immune effector processGO:0002697910.054
membrane disruption in other organismGO:005167310.054
immune responseGO:00069553070.054
small gtpase mediated signal transductionGO:0007264780.053
Mouse
leukocyte apoptotic processGO:0071887310.052
response to external biotic stimulusGO:00432072610.052
cation transportGO:00068123310.051
regulation of gamma delta t cell activation involved in immune responseGO:200119110.050
positive regulation of response to external stimulusGO:0032103880.049
regulation of dendritic cell apoptotic processGO:200066840.049
regulation of cell cycleGO:00517263930.048
nucleoside phosphate catabolic processGO:19012924120.047
purine ribonucleoside catabolic processGO:00461303980.047
regulation of secretionGO:00510461940.046
post embryonic developmentGO:000979120.046
protein localization to plasma membraneGO:0072659930.046
purine nucleoside triphosphate catabolic processGO:00091463920.044
response to bacteriumGO:00096171440.044
regulation of proteolysisGO:00301622930.044
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:200118820.044
regulation of nucleotide catabolic processGO:00308112050.043
single organism membrane organizationGO:00448022680.043
response to fungusGO:000962040.043
fc receptor mediated inhibitory signaling pathwayGO:000277420.042
apoptotic signaling pathwayGO:00971902680.042
nitrogen compound transportGO:00717051910.042
protein processingGO:00164852260.042
positive regulation of programmed cell deathGO:00430682490.041
regulation of cell differentiationGO:00455953930.041
cell chemotaxisGO:00603261120.041
cell morphogenesisGO:00009022960.041
regulation of cell developmentGO:00602841610.040
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:000229140.039
cellular protein complex assemblyGO:00436231880.039
antigen processing and presentationGO:0019882330.039
regulation of cell morphogenesisGO:00226041530.038
cell projection organizationGO:00300302520.038
Mouse
positive regulation of t cell proliferationGO:0042102330.038
negative regulation of cellular component organizationGO:00511292350.038
defense responseGO:00069523150.038
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108110.037
vesicle mediated transportGO:00161923710.037
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092054110.037
regulation of mast cell degranulationGO:004330430.037
regulation of apoptotic signaling pathwayGO:20012331750.037
positive regulation of t cell activationGO:0050870540.037
cellular component morphogenesisGO:00329893140.036
single organism cellular localizationGO:19025803320.036
negative regulation of protein metabolic processGO:00512483910.036
regulation of gamma delta t cell activationGO:004664310.035
regulation of t cell tolerance inductionGO:000266440.035
lymphocyte mediated immunityGO:0002449480.035
regulation of hormone levelsGO:00108171250.035
neutrophil chemotaxisGO:0030593240.034
cellular macromolecular complex assemblyGO:00346223240.034
protein maturationGO:00516042330.034
serotonin transportGO:000683730.034
cell morphogenesis involved in differentiationGO:00009041440.034
inflammatory responseGO:0006954790.034
Rat
secretion by cellGO:00329402260.034
ras protein signal transductionGO:0007265730.034
Mouse
regulation of response to biotic stimulusGO:0002831550.034
regulation of lymphocyte mediated immunityGO:0002706330.033
negative regulation of cell proliferationGO:00082852280.033
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558910.033
immune response in mucosal associated lymphoid tissueGO:000238610.033
organic hydroxy compound transportGO:0015850630.033
antigen processing and presentation of exogenous peptide antigenGO:000247840.033
cation homeostasisGO:00550801890.033
regulation of adaptive immune responseGO:0002819330.033
cellular amine metabolic processGO:0044106410.033
purinergic receptor signaling pathwayGO:003558780.033
amine metabolic processGO:0009308440.033
regulation of osteoclast developmentGO:200120410.032
cytokine biosynthetic processGO:0042089370.032
positive regulation of immune system processGO:00026842830.032
negative regulation of dendritic cell apoptotic processGO:200066930.032
negative regulation of mononuclear cell proliferationGO:0032945150.031
purine nucleotide catabolic processGO:00061954050.031
regulation of leukocyte activationGO:00026941150.031
fc receptor signaling pathwayGO:003809320.031
negative regulation of defense responseGO:0031348470.031
integrin mediated signaling pathwayGO:0007229320.031
response to lipidGO:00339932060.030
Rat
response to biotic stimulusGO:00096072760.030
negative regulation of hydrolase activityGO:00513461820.030
defense response to other organismGO:00985421290.030
positive regulation of transferase activityGO:00513472270.030
oogenesisGO:004847720.030
positive regulation of acute inflammatory responseGO:000267520.030
single organismal cell cell adhesionGO:00163371480.029
immune response regulating signaling pathwayGO:0002764970.029
multicellular organismal agingGO:001025930.029
immune system developmentGO:00025201950.028
single organism cell adhesionGO:00986021790.028
response to other organismGO:00517072610.028
cellular amino acid metabolic processGO:00065201160.028
regulation of nucleoside metabolic processGO:00091182090.028
positive regulation of cellular catabolic processGO:00313312840.027
purinergic nucleotide receptor signaling pathwayGO:003559040.027
cell substrate adhesionGO:00315891320.027
organophosphate catabolic processGO:00464344300.027
monocarboxylic acid metabolic processGO:00327871850.027
regulation of nk t cell activationGO:005113340.027
cell matrix adhesionGO:0007160850.027
cellular response to biotic stimulusGO:0071216710.026
activation of immune responseGO:00022531140.026
negative regulation of cell deathGO:00605483450.026
Rat
gamma delta t cell activationGO:004662930.026
ribonucleoside catabolic processGO:00424544060.026
nucleotide catabolic processGO:00091664080.026
positive regulation of immunoglobulin mediated immune responseGO:000289140.026
acute inflammatory response to antigenic stimulusGO:000243810.025
protein localization to membraneGO:00726571600.025
negative regulation of catalytic activityGO:00430863350.025
regulation of actin cytoskeleton organizationGO:00329561160.025
negative regulation of transforming growth factor beta secretionGO:200120210.024
positive regulation of kinase activityGO:00336742040.024
leukocyte migrationGO:00509001070.024
positive regulation of nucleoside metabolic processGO:00459791860.024
regulation of t cell activationGO:0050863770.024
positive regulation of secretion by cellGO:19035321080.024
protein secretionGO:0009306980.024
negative regulation of cell activationGO:0050866330.024
t cell proliferation involved in immune responseGO:000230910.024
regulation of defense responseGO:00313471540.024
cell adhesionGO:00071553250.023
negative regulation of osteoclast developmentGO:200120510.023
tumor necrosis factor superfamily cytokine productionGO:0071706450.023
regulation of intracellular transportGO:00323861950.023
negative regulation of interleukin 10 productionGO:003269370.023
negative regulation of cellular protein metabolic processGO:00322693530.023
regulation of cytokine productionGO:00018172320.022
nucleoside catabolic processGO:00091644080.022
positive regulation of leukocyte activationGO:0002696800.022
regulation of response to external stimulusGO:00321012220.022
purine ribonucleoside metabolic processGO:00461284370.021
leukocyte mediated immunityGO:0002443590.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
response to cytokineGO:00340972320.021
regulation of interleukin 12 secretionGO:200118210.021
oxidation reduction processGO:00551143960.021
regulation of leukocyte mediated immunityGO:0002703380.021
nervous system developmentGO:00073992930.021
antigen processing and presentation of exogenous antigenGO:001988440.021
nucleoside triphosphate catabolic processGO:00091433940.021
transforming growth factor beta secretionGO:003804410.021
cellular response to lipidGO:00713961270.021
ribonucleoside triphosphate catabolic processGO:00092033910.020
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:200118910.020
positive regulation of apoptotic processGO:00430652460.020
regulation of anatomical structure morphogenesisGO:00226032860.020
cytokine production involved in immune responseGO:0002367270.020
response to molecule of bacterial originGO:0002237820.020
central nervous system developmentGO:00074171230.020
response to lipopolysaccharideGO:0032496700.020
positive regulation of cell proliferationGO:00082843010.019
regulation of endocytosisGO:0030100720.019
cell type specific apoptotic processGO:00972851250.019
cytoplasmic transportGO:00164823790.019
phosphatidylinositol 3 kinase signalingGO:0014065480.019
ribonucleoside triphosphate metabolic processGO:00091994120.018
regulation of locomotionGO:00400123290.018
wound healingGO:00420601150.018
humoral immune responseGO:0006959490.018
vitamin transmembrane transportGO:003546140.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
regulation of cytoskeleton organizationGO:00514931770.018
negative regulation of cell cycleGO:00457861930.018
neuron differentiationGO:00301821380.018
positive regulation of gtpase activityGO:00435471660.018
regulation of body fluid levelsGO:0050878990.017
cellular response to dna damage stimulusGO:00069743790.017
purine ribonucleotide catabolic processGO:00091544040.017
regulation of acute inflammatory response to antigenic stimulusGO:000286410.017
regulation of exocytosisGO:0017157460.017
negative regulation of leukocyte proliferationGO:0070664160.017
determination of adult lifespanGO:000834020.017
regulation of gtpase activityGO:00430871800.017
response to woundingGO:00096111680.017
Rat
leukocyte chemotaxisGO:0030595760.017
positive regulation of protein kinase activityGO:00458601900.017
negative regulation of tumor necrosis factor productionGO:0032720200.017
mast cell activation involved in immune responseGO:000227940.017
detection of triacyl bacterial lipopeptideGO:004249520.017
regulation of cytokine production involved in immune responseGO:0002718220.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
female gamete generationGO:000729220.016
neurogenesisGO:00220081690.016
positive regulation of catabolic processGO:00098963100.016
intrinsic apoptotic signaling pathwayGO:00971931270.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
regulation of production of molecular mediator of immune responseGO:0002700250.016
positive regulation of immune effector processGO:0002699400.016
biological adhesionGO:00226103310.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
positive regulation of innate immune responseGO:0045089790.016
purine containing compound catabolic processGO:00725234110.016
regulation of protein localizationGO:00328802960.016
negative regulation of cd8 positive alpha beta t cell activationGO:200118610.016
regulation of chemotaxisGO:0050920740.016
generation of neuronsGO:00486991520.016
peptidyl tyrosine phosphorylationGO:00181081700.016
organelle localizationGO:0051640840.016
positive regulation of chemotaxisGO:0050921570.016
neuron developmentGO:00486661130.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
ribonucleotide catabolic processGO:00092614050.015
regulation of cytokine secretionGO:0050707570.015
regulation of interleukin 10 secretionGO:200117940.015
interleukin 10 productionGO:0032613170.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.015
nk t cell activationGO:005113240.015
syncytium formation by plasma membrane fusionGO:000076820.015
positive regulation of mast cell activationGO:003300520.015
regulation of endopeptidase activityGO:00525481700.015
negative regulation of secretionGO:0051048580.015
negative regulation of intracellular signal transductionGO:19025321830.015
actin filament bundle assemblyGO:0051017540.015
guanosine containing compound catabolic processGO:19010692390.015
regulation of protein ubiquitinationGO:0031396950.015
rho protein signal transductionGO:0007266260.015
protein polymerizationGO:0051258710.015
hemopoiesisGO:00300971800.015
chemotaxisGO:00069351570.015
leukocyte activation involved in immune responseGO:0002366300.015
regulation of ras gtpase activityGO:00323181280.014
establishment of protein localization to membraneGO:00901501210.014
cellular macromolecule catabolic processGO:00442653800.014
granulocyte chemotaxisGO:0071621370.014
cellular response to molecule of bacterial originGO:0071219620.014
regulation of nucleotide metabolic processGO:00061402690.014
regulation of b cell receptor signaling pathwayGO:005085540.014
positive regulation of behaviorGO:0048520600.014
negative regulation of secretion by cellGO:1903531520.014
regulation of cell cycle processGO:00105642660.014
positive regulation of nucleotide metabolic processGO:00459812300.014
nucleoside triphosphate metabolic processGO:00091414220.014
regulation of kinase activityGO:00435493140.014
regulation of cell morphogenesis involved in differentiationGO:0010769830.014
regulation of transferase activityGO:00513383550.014
immune response regulating cell surface receptor signaling pathwayGO:0002768510.014
positive regulation of secretionGO:00510471160.014
negative regulation of cell differentiationGO:00455961710.014
protein catabolic processGO:00301633250.014
tissue migrationGO:00901301190.014
neuromuscular junction developmentGO:000752830.014
negative regulation of cytokine productionGO:0001818820.013
regulation of cellular amino acid metabolic processGO:000652160.013
ameboidal type cell migrationGO:00016671350.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of leukocyte migrationGO:0002685630.013
defense response to virusGO:0051607710.013
calcium mediated signalingGO:0019722440.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
positive regulation of mononuclear cell proliferationGO:0032946470.013
regulation of transforming growth factor beta secretionGO:200120110.013
response to inorganic substanceGO:00100351270.013
positive regulation of tumor necrosis factor productionGO:0032760210.013
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.013
regulation of cellular component biogenesisGO:00440872810.013
regulation of rho gtpase activityGO:0032319660.013
regulation of tumor necrosis factor productionGO:0032680430.013
negative regulation of programmed cell deathGO:00430693210.013
Rat
myoblast fusionGO:000752010.013
regulation of rho protein signal transductionGO:0035023790.013
response to radiationGO:00093141510.012
cellular response to triacyl bacterial lipopeptideGO:007172720.012
negative regulation of phosphorus metabolic processGO:00105632670.012
secretionGO:00469032540.012
taxisGO:00423301570.012
regulation of nervous system developmentGO:0051960880.012
coagulationGO:0050817780.012
t cell tolerance inductionGO:000251740.012
detection of stimulusGO:0051606850.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
regulation of leukocyte apoptotic processGO:2000106250.012
regulation of protein processingGO:00706131500.012
positive regulation of ras gtpase activityGO:00323201170.012
positive regulation of cellular component organizationGO:00511303760.012
positive regulation of cellular amine metabolic processGO:003324070.012
astrocyte differentiationGO:004870840.012
organelle assemblyGO:00709251760.012
positive regulation of cell motilityGO:20001471770.012
negative regulation of protein maturationGO:19033181420.012
regulation of interleukin 10 productionGO:0032653160.012
myeloid leukocyte differentiationGO:0002573600.012
post embryonic organ developmentGO:004856910.012
peptidyl tyrosine modificationGO:00182121700.012
positive regulation of t cell tolerance inductionGO:000266620.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
regulation of peptidase activityGO:00525471800.011
protein localization to organelleGO:00333652800.011
intracellular protein transportGO:00068862700.011
type i interferon secretionGO:007264110.011
carbohydrate metabolic processGO:00059752070.011
osteoclast developmentGO:003603520.011
guanosine containing compound metabolic processGO:19010682440.011
regulation of response to dna damage stimulusGO:2001020940.011
hemostasisGO:0007599760.011
regulation of innate immune responseGO:0045088970.011
positive regulation of b cell mediated immunityGO:000271440.011
posttranscriptional regulation of gene expressionGO:00106082130.011
cell activation involved in immune responseGO:0002263300.011
dephosphorylationGO:00163112090.011
growthGO:00400072020.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.011
cell part morphogenesisGO:00329901370.011
mitotic nuclear divisionGO:00070671190.010
purine nucleoside catabolic processGO:00061523980.010
cellular response to abiotic stimulusGO:00712141170.010
positive regulation of vasoconstrictionGO:004590730.010
cellular protein catabolic processGO:00442572610.010
negative regulation of ion transportGO:0043271390.010
sulfur compound metabolic processGO:00067901010.010
immune response activating cell surface receptor signaling pathwayGO:0002429450.010
interferon beta productionGO:0032608230.010
positive regulation of leukocyte differentiationGO:1902107370.010
regulation of protein maturationGO:19033171500.010
calcium ion transportGO:00068161470.010
spermatid developmentGO:000728640.010
positive regulation of proteolysisGO:00458621420.010

AIF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.013
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011
sensory system diseaseDOID:00501552030.011
nervous system diseaseDOID:8634310.011