Homo sapiens

32 known processes

ORAI1

ORAI calcium release-activated calcium modulator 1

(Aliases: FLJ14466,CRACM1,ORAT1,TMEM142A)

ORAI1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of store operated calcium channel activityGO:190134140.756
cation transmembrane transportGO:00986552380.446
cation transportGO:00068123310.415
ion transmembrane transportGO:00342203380.398
activation of store operated calcium channel activityGO:003223740.383
calcium ion transmembrane transportGO:0070588760.351
transmembrane transportGO:00550853990.333
regulation of calcium ion transportGO:0051924790.316
inorganic cation transmembrane transportGO:00986621940.306
inorganic ion transmembrane transportGO:00986602310.305
divalent inorganic cation transportGO:00725111580.298
positive regulation of calcium ion transportGO:0051928510.286
divalent metal ion transportGO:00708381520.273
positive regulation of ion transportGO:0043270870.250
calcium ion transportGO:00068161470.246
regulation of calcium ion transmembrane transporter activityGO:1901019280.216
regulation of metal ion transportGO:00109591200.204
positive regulation of ion transmembrane transporter activityGO:0032414290.183
regulation of transmembrane transportGO:00347621390.157
metal ion homeostasisGO:00550651690.156
positive regulation of transporter activityGO:0032411320.155
regulation of transmembrane transporter activityGO:0022898740.146
cation homeostasisGO:00550801890.142
cellular ion homeostasisGO:00068731680.138
positive regulation of transportGO:00510503360.132
regulation of cation channel activityGO:2001257330.131
detection of chemical stimulusGO:0009593550.122
cellular homeostasisGO:00197251960.121
cellular cation homeostasisGO:00300031630.119
regulation of ion transmembrane transportGO:00347651320.115
cellular metal ion homeostasisGO:00068751460.107
ion homeostasisGO:00508012300.104
regulation of ion transmembrane transporter activityGO:0032412720.102
detection of stimulusGO:0051606850.097
response to calcium ionGO:0051592460.097
regulation of transporter activityGO:0032409820.096
cellular divalent inorganic cation homeostasisGO:00725031280.089
positive regulation of ion transmembrane transportGO:0034767400.085
chemical homeostasisGO:00488783060.082
regulation of calcium ion transmembrane transportGO:1903169280.082
cellular calcium ion homeostasisGO:00068741170.072
cellular chemical homeostasisGO:00550821800.071
positive regulation of transmembrane transportGO:0034764410.066
positive regulation of calcium ion transmembrane transporter activityGO:1901021130.063
response to inorganic substanceGO:00100351270.061
post embryonic developmentGO:000979120.059
cellular amine metabolic processGO:0044106410.057
regulation of cellular amine metabolic processGO:0033238110.054
small gtpase mediated signal transductionGO:0007264780.050
positive regulation of phosphorylationGO:00423273940.045
multicellular organismal agingGO:001025930.042
amine metabolic processGO:0009308440.041
cellular ketone metabolic processGO:0042180800.040
cellular response to endogenous stimulusGO:00714953360.040
regulation of cellular ketone metabolic processGO:0010565500.040
positive regulation of cation channel activityGO:2001259160.039
nucleoside triphosphate catabolic processGO:00091433940.039
determination of adult lifespanGO:000834020.037
response to metal ionGO:0010038840.036
positive regulation of cellular amine metabolic processGO:003324070.035
ras protein signal transductionGO:0007265730.034
metal ion transportGO:00300012720.033
actin filament based processGO:00300292240.032
nucleotide catabolic processGO:00091664080.032
organophosphate catabolic processGO:00464344300.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
purine ribonucleoside metabolic processGO:00461284370.030
defense responseGO:00069523150.029
store operated calcium entryGO:000211530.029
Mouse Rat
cellular amino acid metabolic processGO:00065201160.029
cellular response to oxygen containing compoundGO:19017012760.028
negative regulation of catalytic activityGO:00430863350.028
nucleoside phosphate catabolic processGO:19012924120.028
lipid metabolic processGO:00066293810.027
locomotory behaviorGO:000762610.027
glycosyl compound catabolic processGO:19016584130.027
regulation of kinase activityGO:00435493140.026
regulation of ion transportGO:00432691890.026
positive regulation of protein phosphorylationGO:00019343130.026
negative regulation of protein metabolic processGO:00512483910.026
ribonucleoside triphosphate metabolic processGO:00091994120.025
purine nucleoside catabolic processGO:00061523980.025
ribonucleoside catabolic processGO:00424544060.025
regulation of protein kinase activityGO:00458592890.025
regulation of nucleoside metabolic processGO:00091182090.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
regulation of cellular amino acid metabolic processGO:000652160.025
segmentationGO:003528240.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
system processGO:00030083490.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
response to abiotic stimulusGO:00096283360.024
positive regulation of catabolic processGO:00098963100.024
positive regulation of cellular catabolic processGO:00313312840.024
cellular response to dna damage stimulusGO:00069743790.024
immune responseGO:00069553070.024
signal transduction by phosphorylationGO:00230142970.024
positive regulation of cellular component organizationGO:00511303760.023
mapk cascadeGO:00001652880.023
positive regulation of hydrolase activityGO:00513453310.023
cytoplasmic transportGO:00164823790.023
protein catabolic processGO:00301633250.023
negative regulation of cellular protein metabolic processGO:00322693530.023
rho protein signal transductionGO:0007266260.022
regulation of cytokine productionGO:00018172320.022
cell adhesionGO:00071553250.022
nucleoside catabolic processGO:00091644080.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
regulation of cellular response to stressGO:00801352440.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
regulation of protein localizationGO:00328802960.022
positive regulation of transferase activityGO:00513472270.022
female gamete generationGO:000729220.021
regulation of purine nucleotide metabolic processGO:19005422640.021
anion transportGO:00068201610.021
cellular macromolecule catabolic processGO:00442653800.021
single organism cellular localizationGO:19025803320.021
intracellular protein transportGO:00068862700.021
biological adhesionGO:00226103310.020
response to external biotic stimulusGO:00432072610.020
regenerationGO:003109940.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
detection of calcium ionGO:000551380.020
multi organism cellular processGO:00447641560.020
positive regulation of immune system processGO:00026842830.020
purine nucleotide catabolic processGO:00061954050.020
guanosine containing compound metabolic processGO:19010682440.020
purine containing compound catabolic processGO:00725234110.020
innate immune responseGO:00450871780.020
cell morphogenesisGO:00009022960.020
regulation of proteolysisGO:00301622930.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
organonitrogen compound biosynthetic processGO:19015662000.019
gtp catabolic processGO:00061842370.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of cell cycle processGO:00105642660.019
regulation of cell cycleGO:00517263930.019
positive regulation of cellular component movementGO:00512721810.019
regulation of nucleotide catabolic processGO:00308112050.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of nucleotide metabolic processGO:00061402690.019
cellular protein catabolic processGO:00442572610.018
response to oxygen containing compoundGO:19017003690.018
regulation of cell motilityGO:20001452990.018
mitotic cell cycleGO:00002783260.018
anterior posterior axis specificationGO:000994820.018
cellular response to nitrogen compoundGO:19016991440.018
nervous system developmentGO:00073992930.018
cytokine productionGO:00018162470.018
membrane organizationGO:00610242920.018
protein maturationGO:00516042330.018
ribonucleotide catabolic processGO:00092614050.018
response to biotic stimulusGO:00096072760.018
response to nitrogen compoundGO:19016981840.018
purine ribonucleotide catabolic processGO:00091544040.018
maintenance of locationGO:00512351120.017
regulation of gtpase activityGO:00430871800.017
interspecies interaction between organismsGO:00444191560.017
histone modificationGO:00165702510.017
nucleoside triphosphate metabolic processGO:00091414220.017
dephosphorylationGO:00163112090.017
g protein coupled receptor signaling pathwayGO:00071862070.017
vesicle mediated transportGO:00161923710.017
negative regulation of phosphate metabolic processGO:00459362670.017
positive regulation of cell motilityGO:20001471770.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
regulation of cellular component biogenesisGO:00440872810.017
regulation of cell differentiationGO:00455953930.017
response to other organismGO:00517072610.017
positive regulation of kinase activityGO:00336742040.017
carbohydrate derivative biosynthetic processGO:19011372070.017
regulation of purine nucleotide catabolic processGO:00331212050.017
cellular component morphogenesisGO:00329893140.016
positive regulation of cell proliferationGO:00082843010.016
negative regulation of cellular amine metabolic processGO:003323930.016
negative regulation of cell proliferationGO:00082852280.016
response to cytokineGO:00340972320.016
negative regulation of phosphorus metabolic processGO:00105632670.016
regulation of cellular component movementGO:00512703340.016
negative regulation of apoptotic processGO:00430663160.016
cellular response to organonitrogen compoundGO:00714171240.016
negative regulation of intracellular signal transductionGO:19025321830.016
negative regulation of cellular component organizationGO:00511292350.016
protein ubiquitinationGO:00165673140.016
purine ribonucleoside catabolic processGO:00461303980.016
endosomal transportGO:00161971290.016
single organism membrane organizationGO:00448022680.016
nuclear transportGO:00511691790.016
cell growthGO:00160491600.016
protein autophosphorylationGO:00467771230.016
protein localization to organelleGO:00333652800.016
negative regulation of hydrolase activityGO:00513461820.016
adult locomotory behaviorGO:000834410.015
apoptotic signaling pathwayGO:00971902680.015
secretionGO:00469032540.015
regulation of anatomical structure morphogenesisGO:00226032860.015
cellular response to abiotic stimulusGO:00712141170.015
negative regulation of multicellular organismal processGO:00512413170.015
endomembrane system organizationGO:00102561960.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
regulation of cytoskeleton organizationGO:00514931770.015
regulation of response to external stimulusGO:00321012220.015
regulation of protein catabolic processGO:00421761550.015
memoryGO:000761330.015
regulation of immune responseGO:00507762010.015
positive regulation of gtp catabolic processGO:00331261660.015
covalent chromatin modificationGO:00165692540.015
neuromuscular junction developmentGO:000752830.015
spermatid differentiationGO:004851540.015
response to organonitrogen compoundGO:00102431560.015
oogenesisGO:004847720.015
cell projection organizationGO:00300302520.015
oxidation reduction processGO:00551143960.015
response to hormoneGO:00097251750.015
positive regulation of cell migrationGO:00303351720.015
blastoderm segmentationGO:000735020.015
protein targetingGO:00066051870.015
positive regulation of organelle organizationGO:00106381950.015
nucleocytoplasmic transportGO:00069131760.015
alcohol metabolic processGO:00060661140.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
response to growth factorGO:00708482050.014
nitrogen compound transportGO:00717051910.014
secretion by cellGO:00329402260.014
positive regulation of mapk cascadeGO:00434101900.014
negative regulation of programmed cell deathGO:00430693210.014
carbohydrate metabolic processGO:00059752070.014
positive regulation of nucleoside metabolic processGO:00459791860.014
regulation of transferase activityGO:00513383550.014
regulation of locomotionGO:00400123290.014
hyperosmotic responseGO:000697240.014
regulation of cell migrationGO:00303342890.014
tripartite regional subdivisionGO:000735120.014
negative regulation of cell deathGO:00605483450.014
spermatid developmentGO:000728640.014
proteasomal protein catabolic processGO:00104981760.014
positive regulation of nucleotide catabolic processGO:00308131850.014
negative regulation of protein modification processGO:00314002000.014
gtp metabolic processGO:00460392390.014
protein processingGO:00164852260.014
peptidyl serine phosphorylationGO:00181051010.014
peripheral nervous system developmentGO:000742220.014
guanosine containing compound catabolic processGO:19010692390.014
cell activationGO:00017752130.013
actin cytoskeleton organizationGO:00300362070.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
reactive nitrogen species metabolic processGO:200105730.013
microtubule based processGO:00070172100.013
positive regulation of cell differentiationGO:00455972110.013
anterior posterior axis specification embryoGO:000859520.013
regulation of endopeptidase activityGO:00525481700.013
establishment of protein localization to organelleGO:00725941720.013
mitotic cell cycle processGO:19030472860.013
protein modification by small protein conjugationGO:00324463420.013
posttranscriptional regulation of gene expressionGO:00106082130.013
organelle assemblyGO:00709251760.013
regulation of actin filament based processGO:00329701410.013
regulation of intracellular transportGO:00323861950.013
epithelium developmentGO:00604292270.013
negative regulation of cytokine productionGO:0001818820.013
compound eye developmentGO:004874910.013
response to fungusGO:000962040.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
regulation of ras protein signal transductionGO:00465781550.013
single organism carbohydrate metabolic processGO:00447231930.013
response to salt stressGO:000965130.013
chromatin modificationGO:00165682980.013
positive regulation of cellular component biogenesisGO:00440891580.013
cellular protein complex assemblyGO:00436231880.012
regulation of store operated calcium channel activityGO:190133940.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
epithelium migrationGO:00901321190.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
regulation of establishment of protein localizationGO:00702012420.012
oocyte developmentGO:004859910.012
cell divisionGO:00513011680.012
organic hydroxy compound metabolic processGO:19016151470.012
associative learningGO:000830610.012
positive regulation of apoptotic processGO:00430652460.012
positive regulation of ras gtpase activityGO:00323201170.012
defense response to fungusGO:005083240.012
ubiquitin dependent protein catabolic processGO:00065112060.012
negative regulation of cell cycleGO:00457861930.012
organic anion transportGO:00157111030.012
positive regulation of cell deathGO:00109422630.012
regulation of protein transportGO:00512232130.012
regulation of cell morphogenesisGO:00226041530.012
peptidyl serine modificationGO:00182091060.012
neurological system processGO:00508771630.012
regulation of cell adhesionGO:00301551660.012
viral life cycleGO:00190581320.012
epithelial cell migrationGO:00106311190.012
regulation of peptidase activityGO:00525471800.012
regulation of cell growthGO:00015581350.012
rna processingGO:00063962550.012
regulation of mapk cascadeGO:00434082620.012
dna repairGO:00062811980.012
head developmentGO:00603221080.012
cell projection assemblyGO:00300311260.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
cellular response to cytokine stimulusGO:00713451810.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
ameboidal type cell migrationGO:00016671350.012
positive regulation of programmed cell deathGO:00430682490.012
response to lipidGO:00339932060.012
rhythmic behaviorGO:000762220.011
positive regulation of gtpase activityGO:00435471660.011
protein acylationGO:00435431380.011
positive regulation of proteolysisGO:00458621420.011
negative regulation of transportGO:00510511760.011
positive regulation of synaptic transmissionGO:005080640.011
morphogenesis of embryonic epitheliumGO:001633140.011
embryonic epithelial tube formationGO:000183840.011
regulation of protein maturationGO:19033171500.011
regulation of protein complex assemblyGO:00432541470.011
rab protein signal transductionGO:003248240.011
positive regulation of nucleotide metabolic processGO:00459812300.011
positive regulation of locomotionGO:00400171860.011
response to axon injuryGO:004867810.011
protein localization to membraneGO:00726571600.011
cellular response to external stimulusGO:00714961110.011
regulation of gtp catabolic processGO:00331241800.011
sequestering of metal ionGO:0051238240.011
hindbrain developmentGO:003090230.011
negative regulation of phosphorylationGO:00423261740.011
endocytosisGO:00068971590.011
syncytium formation by plasma membrane fusionGO:000076820.011
oocyte differentiationGO:000999420.011
t cell differentiation in thymusGO:003307740.011
reactive oxygen species biosynthetic processGO:190340940.011
positive regulation of cell cycleGO:00457871400.011
response to bacteriumGO:00096171440.011
circadian behaviorGO:004851220.011
negative regulation of protein phosphorylationGO:00019331400.011
regulation of multi organism processGO:00439001570.011
negative regulation of protein processingGO:00109551420.011
response to woundingGO:00096111680.011
nuclear importGO:00511701060.011
cellular response to growth factor stimulusGO:00713631970.011
viral processGO:00160321460.011
immune effector processGO:00022521590.010
modification dependent macromolecule catabolic processGO:00436322120.010
cell cycle phase transitionGO:00447701730.010
protein import into nucleusGO:00066061040.010
regulation of secretion by cellGO:19035301770.010
regulation of synaptic plasticityGO:004816730.010
protein localization to nucleusGO:00345041360.010
regulation of cytoplasmic transportGO:19036491490.010
sequestering of calcium ionGO:0051208170.010
matingGO:000761810.010
regulation of dna metabolic processGO:00510521530.010
regulation of viral processGO:00507921030.010
regulation of protein processingGO:00706131500.010
response to organic cyclic compoundGO:00140702040.010
protein oligomerizationGO:00512591730.010
glycoprotein metabolic processGO:00091001100.010
positive regulation of immune responseGO:00507781590.010
single organism cell adhesionGO:00986021790.010
monovalent inorganic cation transportGO:00156721280.010
immune system developmentGO:00025201950.010
atp metabolic processGO:00460341760.010
lens development in camera type eyeGO:000208820.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010

ORAI1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.023
disease of metabolismDOID:00146672950.021
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
inherited metabolic disorderDOID:6552420.018
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
neurodegenerative diseaseDOID:12891020.014
sensory system diseaseDOID:00501552030.013
immune system diseaseDOID:29141550.012
connective tissue diseaseDOID:651090.012
eye and adnexa diseaseDOID:14921500.011
eye diseaseDOID:56141490.011
muscle tissue diseaseDOID:661130.010
muscular diseaseDOID:00800001140.010