| g protein coupled receptor signaling pathway | GO:0007186 | 207 | 0.997 | |
| gtp catabolic process | GO:0006184 | 237 | 0.890 | |
| cellular response to parathyroid hormone stimulus | GO:0071374 | 2 | 0.862 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.853 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.828 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.807 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.806 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.766 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.763 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.758 | |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.737 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.731 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.728 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.704 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.702 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.700 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.681 | Human |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.678 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.648 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.648 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.618 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.603 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.601 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.597 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.595 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.592 | |
| gtp metabolic process | GO:0046039 | 239 | 0.592 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.588 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.576 | |
| phototransduction visible light | GO:0007603 | 2 | 0.574 | Human |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.572 | |
| response to parathyroid hormone | GO:0071107 | 3 | 0.560 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.557 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.556 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.550 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.538 | |
| tricarboxylic acid metabolic process | GO:0072350 | 4 | 0.538 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.535 | |
| regulation of rhodopsin mediated signaling pathway | GO:0022400 | 1 | 0.528 | Human |
| regulation of gtpase activity | GO:0043087 | 180 | 0.525 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.514 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.514 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.511 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.500 | |
| regulation of g protein coupled receptor protein signaling pathway | GO:0008277 | 35 | 0.498 | Human Mouse Rat |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.497 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.495 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.489 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.486 | |
| regulation of cell motility | GO:2000145 | 299 | 0.483 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.483 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.479 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.478 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.478 | |
| ameboidal type cell migration | GO:0001667 | 135 | 0.468 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.458 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.449 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.443 | |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.433 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.428 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.427 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.427 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.426 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.410 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.405 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.405 | |
| activation of mapk activity | GO:0000187 | 45 | 0.389 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.389 | |
| response to growth factor | GO:0070848 | 205 | 0.388 | |
| secretion by cell | GO:0032940 | 226 | 0.383 | Rat |
| response to oxygen containing compound | GO:1901700 | 369 | 0.371 | Rat |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.365 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.362 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.340 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.339 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.328 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.327 | Human |
| positive regulation of cellular component movement | GO:0051272 | 181 | 0.323 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.317 | |
| protein catabolic process | GO:0030163 | 325 | 0.315 | |
| regulation of microtubule based process | GO:0032886 | 74 | 0.309 | |
| hydrogen peroxide mediated programmed cell death | GO:0010421 | 4 | 0.307 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.287 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.286 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.274 | |
| histone modification | GO:0016570 | 251 | 0.273 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 82 | 0.268 | |
| programmed cell death in response to reactive oxygen species | GO:0097468 | 4 | 0.264 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.259 | |
| chromatin organization | GO:0006325 | 351 | 0.254 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.242 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.227 | |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.220 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.218 | |
| cation homeostasis | GO:0055080 | 189 | 0.215 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 61 | 0.214 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.212 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.211 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.211 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.205 | |
| histone deacetylation | GO:0016575 | 32 | 0.204 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.196 | Human |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.196 | |
| somatic muscle development | GO:0007525 | 1 | 0.193 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.188 | |
| protein ubiquitination | GO:0016567 | 314 | 0.186 | |
| positive regulation of locomotion | GO:0040017 | 186 | 0.182 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.182 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.180 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.179 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.177 | |
| phototransduction | GO:0007602 | 3 | 0.177 | Human |
| chemical homeostasis | GO:0048878 | 306 | 0.177 | |
| cellular homeostasis | GO:0019725 | 196 | 0.174 | |
| misfolded protein transport | GO:0070843 | 1 | 0.174 | |
| cellular response to hormone stimulus | GO:0032870 | 125 | 0.172 | |
| amine metabolic process | GO:0009308 | 44 | 0.169 | |
| tricarboxylic acid cycle | GO:0006099 | 4 | 0.169 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.168 | |
| chromatin modification | GO:0016568 | 298 | 0.168 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.167 | |
| lipid metabolic process | GO:0006629 | 381 | 0.167 | |
| detection of stimulus | GO:0051606 | 85 | 0.167 | Human |
| regulation of hydrogen peroxide mediated programmed cell death | GO:1901298 | 4 | 0.166 | |
| regulation of epithelial cell migration | GO:0010632 | 93 | 0.166 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.163 | |
| oogenesis | GO:0048477 | 2 | 0.161 | |
| regulation of locomotion | GO:0040012 | 329 | 0.161 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.158 | Human |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.157 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.156 | |
| receptor metabolic process | GO:0043112 | 81 | 0.156 | |
| positive regulation of cell motility | GO:2000147 | 177 | 0.155 | |
| protein k63 linked deubiquitination | GO:0070536 | 21 | 0.155 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.155 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.149 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.148 | |
| tissue migration | GO:0090130 | 119 | 0.148 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.147 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.142 | |
| oxidation reduction process | GO:0055114 | 396 | 0.141 | |
| cellular response to misfolded protein | GO:0071218 | 2 | 0.141 | |
| epithelial cell migration | GO:0010631 | 119 | 0.141 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.140 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 45 | 0.140 | |
| positive regulation of cell division | GO:0051781 | 59 | 0.138 | |
| positive regulation of cell migration | GO:0030335 | 172 | 0.137 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.136 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.131 | |
| epithelium migration | GO:0090132 | 119 | 0.129 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.129 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.129 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.129 | |
| cell junction assembly | GO:0034329 | 67 | 0.128 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.127 | |
| mapk cascade | GO:0000165 | 288 | 0.125 | |
| response to hormone | GO:0009725 | 175 | 0.124 | |
| cell development | GO:0048468 | 328 | 0.122 | |
| detection of visible light | GO:0009584 | 11 | 0.122 | Human |
| protein deacylation | GO:0035601 | 39 | 0.121 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.121 | |
| female gamete generation | GO:0007292 | 2 | 0.120 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.119 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.118 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.118 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.118 | |
| cell adhesion | GO:0007155 | 325 | 0.118 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.118 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.118 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.116 | Rat |
| response to light stimulus | GO:0009416 | 87 | 0.115 | Human |
| post embryonic development | GO:0009791 | 2 | 0.114 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.114 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.113 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.112 | |
| immune system development | GO:0002520 | 195 | 0.112 | |
| peptidyl lysine deacetylation | GO:0034983 | 6 | 0.111 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.111 | |
| cell morphogenesis | GO:0000902 | 296 | 0.110 | |
| biological adhesion | GO:0022610 | 331 | 0.110 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.108 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.104 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.099 | |
| regulation of cell migration | GO:0030334 | 289 | 0.099 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.098 | |
| detection of abiotic stimulus | GO:0009582 | 15 | 0.098 | Human |
| vesicle mediated transport | GO:0016192 | 371 | 0.097 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.097 | |
| system process | GO:0003008 | 349 | 0.096 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.095 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.095 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.095 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.094 | |
| intracellular protein transport | GO:0006886 | 270 | 0.094 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.089 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.088 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.088 | |
| rhodopsin mediated signaling pathway | GO:0016056 | 1 | 0.087 | Human |
| positive regulation of cell development | GO:0010720 | 92 | 0.087 | |
| protein deubiquitination | GO:0016579 | 79 | 0.087 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.087 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.086 | Human |
| positive regulation of epithelial cell migration | GO:0010634 | 55 | 0.085 | |
| circulatory system process | GO:0003013 | 113 | 0.084 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.084 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.083 | |
| tachykinin receptor signaling pathway | GO:0007217 | 3 | 0.082 | |
| muscle structure development | GO:0061061 | 98 | 0.082 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.081 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.079 | |
| positive regulation of rho gtpase activity | GO:0032321 | 56 | 0.079 | |
| neuron differentiation | GO:0030182 | 138 | 0.079 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.078 | Human Worm |
| regulation of cell development | GO:0060284 | 161 | 0.078 | |
| negative regulation of microtubule polymerization or depolymerization | GO:0031111 | 17 | 0.078 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 24 | 0.078 | |
| neurological system process | GO:0050877 | 163 | 0.076 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.076 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.076 | |
| macromolecule deacylation | GO:0098732 | 41 | 0.075 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.075 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.075 | |
| signal release | GO:0023061 | 70 | 0.075 | |
| response to oxidative stress | GO:0006979 | 121 | 0.074 | Rat |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.074 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.074 | Human |
| autophagy | GO:0006914 | 88 | 0.074 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.074 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.072 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.072 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.072 | |
| positive regulation of rac gtpase activity | GO:0032855 | 31 | 0.071 | |
| negative regulation of multi organism process | GO:0043901 | 92 | 0.071 | |
| positive regulation of lipopolysaccharide mediated signaling pathway | GO:0031666 | 4 | 0.070 | |
| sensory perception of light stimulus | GO:0050953 | 35 | 0.070 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 35 | 0.069 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.069 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.069 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.068 | |
| epithelium development | GO:0060429 | 227 | 0.068 | |
| protein complex disassembly | GO:0043241 | 52 | 0.067 | |
| regulation of hydrogen peroxide induced cell death | GO:1903205 | 10 | 0.067 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.066 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.066 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.064 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.064 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.064 | |
| blood circulation | GO:0008015 | 113 | 0.064 | |
| cellular response to topologically incorrect protein | GO:0035967 | 19 | 0.063 | |
| oocyte development | GO:0048599 | 1 | 0.063 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.063 | |
| regulation of ion transport | GO:0043269 | 189 | 0.063 | |
| single organism nuclear import | GO:1902593 | 104 | 0.062 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.062 | |
| regulation of protein localization | GO:0032880 | 296 | 0.062 | |
| secretion | GO:0046903 | 254 | 0.061 | Rat |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.061 | |
| generation of neurons | GO:0048699 | 152 | 0.061 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.061 | |
| cell cell signaling | GO:0007267 | 155 | 0.060 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.060 | |
| regulation of rho protein signal transduction | GO:0035023 | 79 | 0.060 | |
| cellular glucuronidation | GO:0052695 | 16 | 0.059 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.059 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.059 | |
| regulation of neuronal synaptic plasticity | GO:0048168 | 1 | 0.059 | |
| response to radiation | GO:0009314 | 151 | 0.058 | Human |
| epithelial cell development | GO:0002064 | 34 | 0.058 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.058 | |
| ion homeostasis | GO:0050801 | 230 | 0.058 | |
| behavior | GO:0007610 | 112 | 0.058 | Worm |
| regulation of neurotransmitter levels | GO:0001505 | 15 | 0.057 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 26 | 0.057 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.057 | |
| protein processing | GO:0016485 | 226 | 0.057 | |
| response to reactive oxygen species | GO:0000302 | 61 | 0.056 | Rat |
| rac protein signal transduction | GO:0016601 | 12 | 0.056 | |
| activation of protein kinase activity | GO:0032147 | 90 | 0.056 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.056 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.055 | |
| cell death in response to hydrogen peroxide | GO:0036474 | 10 | 0.055 | |
| phospholipase c activating g protein coupled receptor signaling pathway | GO:0007200 | 15 | 0.055 | |
| uronic acid metabolic process | GO:0006063 | 16 | 0.055 | |
| inclusion body assembly | GO:0070841 | 17 | 0.055 | |
| cell cell junction organization | GO:0045216 | 69 | 0.055 | |
| regulation of cell junction assembly | GO:1901888 | 29 | 0.055 | |
| oocyte differentiation | GO:0009994 | 2 | 0.054 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.054 | |
| nervous system development | GO:0007399 | 293 | 0.054 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.054 | |
| microtubule based process | GO:0007017 | 210 | 0.053 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.053 | |
| regulation of immune response | GO:0050776 | 201 | 0.053 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.053 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.053 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.053 | |
| activation of immune response | GO:0002253 | 114 | 0.052 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.052 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.052 | |
| glutamate receptor signaling pathway | GO:0007215 | 23 | 0.052 | |
| defense response to other organism | GO:0098542 | 129 | 0.051 | |
| hemopoiesis | GO:0030097 | 180 | 0.051 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.050 | |
| regulation of cellular glucuronidation | GO:2001029 | 5 | 0.050 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.050 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.050 | |
| regulation of behavior | GO:0050795 | 82 | 0.048 | |
| transmembrane transport | GO:0055085 | 399 | 0.048 | |
| negative regulation of chromatin silencing | GO:0031936 | 4 | 0.048 | |
| camp biosynthetic process | GO:0006171 | 47 | 0.047 | |
| negative regulation of protein complex disassembly | GO:0043242 | 20 | 0.047 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 79 | 0.047 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.047 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.047 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.046 | |
| cell death in response to oxidative stress | GO:0036473 | 29 | 0.046 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.046 | |
| cell projection assembly | GO:0030031 | 126 | 0.046 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.046 | Mouse |
| response to other organism | GO:0051707 | 261 | 0.046 | |
| protein deacetylation | GO:0006476 | 38 | 0.046 | |
| nitrogen cycle metabolic process | GO:0071941 | 3 | 0.046 | |
| regulation of chemotaxis | GO:0050920 | 74 | 0.046 | |
| regulation of protein transport | GO:0051223 | 213 | 0.046 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.045 | |
| regulation of defense response | GO:0031347 | 154 | 0.045 | |
| positive regulation of camp biosynthetic process | GO:0030819 | 35 | 0.044 | |
| cellular response to lipid | GO:0071396 | 127 | 0.044 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.043 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.043 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.043 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.043 | |
| macromolecular complex disassembly | GO:0032984 | 60 | 0.043 | |
| endothelial cell migration | GO:0043542 | 86 | 0.043 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.043 | |
| positive regulation of nucleotide biosynthetic process | GO:0030810 | 38 | 0.042 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.042 | |
| protein import | GO:0017038 | 130 | 0.042 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.041 | |
| regulation of cell adhesion | GO:0030155 | 166 | 0.041 | |
| cell projection organization | GO:0030030 | 252 | 0.041 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.039 | |
| positive regulation of meiotic cell cycle | GO:0051446 | 2 | 0.039 | |
| regulation of fat cell differentiation | GO:0045598 | 23 | 0.039 | |
| positive regulation of oxidative stress induced cell death | GO:1903209 | 5 | 0.039 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.039 | |
| cellular response to light stimulus | GO:0071482 | 34 | 0.038 | Human |
| determination of adult lifespan | GO:0008340 | 2 | 0.038 | |
| associative learning | GO:0008306 | 1 | 0.038 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.038 | |
| regulation of endothelial cell migration | GO:0010594 | 67 | 0.038 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.037 | |
| purine containing compound biosynthetic process | GO:0072522 | 88 | 0.037 | |
| protein targeting | GO:0006605 | 187 | 0.037 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.037 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.037 | |
| wound healing | GO:0042060 | 115 | 0.037 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.037 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.037 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.037 | Rat |
| response to oxygen levels | GO:0070482 | 100 | 0.037 | |
| regulation of meiosis | GO:0040020 | 3 | 0.036 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 10 | 0.036 | |
| detection of light stimulus | GO:0009583 | 11 | 0.036 | Human |
| response to lipid | GO:0033993 | 206 | 0.036 | |
| neurogenesis | GO:0022008 | 169 | 0.036 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.036 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 35 | 0.036 | |
| microtubule polymerization or depolymerization | GO:0031109 | 37 | 0.036 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.036 | |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.035 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.035 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.035 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.035 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.035 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.035 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.035 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.035 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.035 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 4 | 0.034 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.034 | |
| oocyte maturation | GO:0001556 | 1 | 0.034 | |
| response to cytokine | GO:0034097 | 232 | 0.034 | |
| blood vessel endothelial cell migration | GO:0043534 | 42 | 0.034 | |
| macroautophagy | GO:0016236 | 39 | 0.034 | |
| regulation of response to biotic stimulus | GO:0002831 | 55 | 0.034 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.034 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.033 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.033 | |
| single organism cellular localization | GO:1902580 | 332 | 0.033 | |
| cell junction organization | GO:0034330 | 79 | 0.033 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.033 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.033 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.033 | |
| receptor internalization | GO:0031623 | 43 | 0.033 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.033 | |
| negative regulation of striated muscle tissue development | GO:0045843 | 11 | 0.032 | |
| erbb signaling pathway | GO:0038127 | 44 | 0.032 | |
| positive regulation of receptor biosynthetic process | GO:0010870 | 8 | 0.032 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.032 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.032 | |
| protein import into nucleus | GO:0006606 | 104 | 0.032 | |
| regulation of response to reactive oxygen species | GO:1901031 | 12 | 0.032 | |
| ribose phosphate biosynthetic process | GO:0046390 | 82 | 0.032 | |
| cellular protein complex disassembly | GO:0043624 | 36 | 0.032 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.032 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.031 | |
| ubiquitin dependent smad protein catabolic process | GO:0030579 | 4 | 0.031 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.031 | |
| inositol lipid mediated signaling | GO:0048017 | 55 | 0.031 | |
| positive regulation of cellular response to oxidative stress | GO:1900409 | 7 | 0.031 | |
| endosome transport via multivesicular body sorting pathway | GO:0032509 | 3 | 0.031 | |
| regulation of n methyl d aspartate selective glutamate receptor activity | GO:2000310 | 1 | 0.031 | |
| cardiovascular system development | GO:0072358 | 262 | 0.031 | Mouse |
| negative regulation of microtubule depolymerization | GO:0007026 | 12 | 0.031 | |
| response to hydrogen peroxide | GO:0042542 | 40 | 0.031 | Rat |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.030 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.030 | |
| cyclic nucleotide metabolic process | GO:0009187 | 82 | 0.030 | |
| regulation of protein depolymerization | GO:1901879 | 22 | 0.030 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 82 | 0.030 | |
| microtubule depolymerization | GO:0007019 | 18 | 0.030 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 99 | 0.030 | |
| regulation of blood vessel endothelial cell migration | GO:0043535 | 30 | 0.030 | |
| skeletal system development | GO:0001501 | 79 | 0.030 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 43 | 0.030 | |
| regulation of camp metabolic process | GO:0030814 | 52 | 0.030 | |
| granulocyte migration | GO:0097530 | 40 | 0.029 | |
| cellular response to hydrogen peroxide | GO:0070301 | 37 | 0.029 | |
| defense response | GO:0006952 | 315 | 0.029 | |
| dna conformation change | GO:0071103 | 113 | 0.029 | |
| generation of precursor metabolites and energy | GO:0006091 | 68 | 0.029 | |
| negative regulation of striated muscle contraction | GO:0045988 | 2 | 0.029 | |
| ncrna metabolic process | GO:0034660 | 108 | 0.029 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.029 | |
| positive regulation of transport | GO:0051050 | 336 | 0.029 | Rat |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.028 | |
| adenylate cyclase modulating g protein coupled receptor signaling pathway | GO:0007188 | 43 | 0.028 | |
| regulation of muscle contraction | GO:0006937 | 45 | 0.028 | |
| cellular component disassembly | GO:0022411 | 92 | 0.028 | |
| sequestering of calcium ion | GO:0051208 | 17 | 0.028 | |
| negative regulation of protein depolymerization | GO:1901880 | 17 | 0.028 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.028 | |
| regulation of cell activation | GO:0050865 | 125 | 0.028 | |
| positive regulation of epidermal growth factor receptor signaling pathway | GO:0045742 | 11 | 0.028 | |
| response to misfolded protein | GO:0051788 | 5 | 0.028 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.028 | |
| positive regulation of cell adhesion | GO:0045785 | 84 | 0.028 | |
| regulation of lipopolysaccharide mediated signaling pathway | GO:0031664 | 13 | 0.027 | |
| regulation of b cell receptor signaling pathway | GO:0050855 | 4 | 0.027 | |
| regulation of receptor activity | GO:0010469 | 47 | 0.027 | |
| positive regulation of neuron differentiation | GO:0045666 | 40 | 0.027 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.027 | |
| regulation of purine nucleotide biosynthetic process | GO:1900371 | 50 | 0.027 | |
| phosphatidylinositol 3 kinase signaling | GO:0014065 | 48 | 0.027 | |
| leukocyte chemotaxis | GO:0030595 | 76 | 0.027 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.027 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.027 | |
| response to dexamethasone | GO:0071548 | 1 | 0.026 | |
| positive regulation of response to oxidative stress | GO:1902884 | 7 | 0.026 | |
| regulation of cytokinesis | GO:0032465 | 45 | 0.026 | |
| cyclic purine nucleotide metabolic process | GO:0052652 | 60 | 0.026 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.026 | |
| compound eye development | GO:0048749 | 1 | 0.025 | |
| maintenance of location | GO:0051235 | 112 | 0.025 | |
| regulation of nucleotide biosynthetic process | GO:0030808 | 50 | 0.025 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 61 | 0.025 | |
| focal adhesion assembly | GO:0048041 | 30 | 0.025 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.025 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 4 | 0.025 | |
| cellular response to reactive oxygen species | GO:0034614 | 50 | 0.025 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.025 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 56 | 0.024 | |
| endosomal transport | GO:0016197 | 129 | 0.024 | |
| phosphatidylinositol mediated signaling | GO:0048015 | 55 | 0.024 | |
| mitochondrion organization | GO:0007005 | 156 | 0.024 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.024 | |
| regulation of cyclic nucleotide biosynthetic process | GO:0030802 | 49 | 0.024 | |
| rap protein signal transduction | GO:0032486 | 7 | 0.024 | |
| g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger | GO:0007187 | 43 | 0.024 | |
| leukocyte activation | GO:0045321 | 164 | 0.024 | |
| citrate metabolic process | GO:0006101 | 2 | 0.024 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.024 | |
| reproductive process | GO:0022414 | 106 | 0.024 | Rat |
| regulation of growth | GO:0040008 | 165 | 0.024 | Worm |