IMP: Integrative Multi-species Prediction

Homo sapiens

38 known processes

ATG4C

ATG4 autophagy related 4 homolog C (S. cerevisiae)

(Aliases: APG4-C,AUTL3,FLJ14867,APG4C,AUTL1)

HPRD: 07473
MIM: 611339
Entrez: 84938
HGNC: 16040
Ensembl: ENSG00000125703
UniProtKB: Q96DT6

Process Predictions
Disease Predictions

ATG4C biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
lipid metabolic process	GO:0006629	381	0.221
lipid biosynthetic process	GO:0008610	177	0.080
cellular lipid metabolic process	GO:0044255	303	0.073
post embryonic development	GO:0009791	2	0.072
amine metabolic process	GO:0009308	44	0.060
cellular amine metabolic process	GO:0044106	41	0.060
carbohydrate metabolic process	GO:0005975	207	0.053
cellular ketone metabolic process	GO:0042180	80	0.044
glycosyl compound catabolic process	GO:1901658	413	0.042
membrane organization	GO:0061024	292	0.042
purine containing compound catabolic process	GO:0072523	411	0.042
single organism membrane organization	GO:0044802	268	0.040
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.040
single organism carbohydrate metabolic process	GO:0044723	193	0.039
organophosphate biosynthetic process	GO:0090407	163	0.039
cellular macromolecular complex assembly	GO:0034622	324	0.038
membrane lipid metabolic process	GO:0006643	53	0.037
nucleoside catabolic process	GO:0009164	408	0.037
establishment or maintenance of epithelial cell apical basal polarity	GO:0045197	1	0.036
cellular macromolecule catabolic process	GO:0044265	380	0.036
protein modification by small protein conjugation	GO:0032446	342	0.034
phospholipid metabolic process	GO:0006644	99	0.033
carbohydrate derivative biosynthetic process	GO:1901137	207	0.033
positive regulation of cellular component organization	GO:0051130	376	0.032
female gamete generation	GO:0007292	2	0.032
oogenesis	GO:0048477	2	0.032
positive regulation of catabolic process	GO:0009896	310	0.032
determination of adult lifespan	GO:0008340	2	0.031
ribonucleoside catabolic process	GO:0042454	406	0.031
small molecule biosynthetic process	GO:0044283	157	0.031
mitochondrion organization	GO:0007005	156	0.030
cellular protein catabolic process	GO:0044257	261	0.028
establishment or maintenance of bipolar cell polarity	GO:0061245	2	0.027
cellular protein complex assembly	GO:0043623	188	0.027
purine nucleoside catabolic process	GO:0006152	398	0.027
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.026
purine nucleotide catabolic process	GO:0006195	405	0.025
ribonucleotide catabolic process	GO:0009261	405	0.024
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.024
negative regulation of programmed cell death	GO:0043069	321	0.024
organophosphate catabolic process	GO:0046434	430	0.024
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.023
locomotory behavior	GO:0007626	1	0.023
regulation of cellular ketone metabolic process	GO:0010565	50	0.023
alcohol metabolic process	GO:0006066	114	0.022
organonitrogen compound biosynthetic process	GO:1901566	200	0.022
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.022
protein ubiquitination	GO:0016567	314	0.021
regulation of cellular amino acid metabolic process	GO:0006521	6	0.021
single organism cellular localization	GO:1902580	332	0.021
multicellular organismal aging	GO:0010259	3	0.021
nucleoside triphosphate metabolic process	GO:0009141	422	0.021
amide biosynthetic process	GO:0043604	15	0.020
chromatin modification	GO:0016568	298	0.020
regulation of cell cycle	GO:0051726	393	0.020
membrane lipid biosynthetic process	GO:0046467	27	0.020
protein polyubiquitination	GO:0000209	110	0.020
nucleoside triphosphate catabolic process	GO:0009143	394	0.020
nucleoside monophosphate catabolic process	GO:0009125	159	0.020
establishment or maintenance of apical basal cell polarity	GO:0035088	2	0.019
vesicle mediated transport	GO:0016192	371	0.019
regulation of mitochondrion organization	GO:0010821	54	0.018
negative regulation of cellular component organization	GO:0051129	235	0.018
purine ribonucleoside metabolic process	GO:0046128	437	0.018
dephosphorylation	GO:0016311	209	0.018
regulation of cellular component biogenesis	GO:0044087	281	0.018
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.017
cellular homeostasis	GO:0019725	196	0.017
negative regulation of organelle organization	GO:0010639	126	0.017
secretion	GO:0046903	254	0.017
nucleoside phosphate catabolic process	GO:1901292	412	0.017
mitotic cell cycle	GO:0000278	326	0.017
cellular amino acid metabolic process	GO:0006520	116	0.017
glycoprotein biosynthetic process	GO:0009101	91	0.017
protein localization to organelle	GO:0033365	280	0.016
organic hydroxy compound biosynthetic process	GO:1901617	71	0.016
regulation of cellular response to stress	GO:0080135	244	0.016
cellular response to dna damage stimulus	GO:0006974	379	0.016
nucleotide catabolic process	GO:0009166	408	0.016
negative regulation of catalytic activity	GO:0043086	335	0.016
response to abiotic stimulus	GO:0009628	336	0.016
protein catabolic process	GO:0030163	325	0.016
phospholipid biosynthetic process	GO:0008654	44	0.015
negative regulation of apoptotic process	GO:0043066	316	0.015
apoptotic signaling pathway	GO:0097190	268	0.015
atp catabolic process	GO:0006200	157	0.015
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.015
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.015
purine ribonucleotide catabolic process	GO:0009154	404	0.015
segmentation	GO:0035282	4	0.015
negative regulation of phosphorus metabolic process	GO:0010563	267	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.015
glycerolipid metabolic process	GO:0046486	107	0.015
histone modification	GO:0016570	251	0.015
blastoderm segmentation	GO:0007350	2	0.015
negative regulation of protein metabolic process	GO:0051248	391	0.015
glycoprotein metabolic process	GO:0009100	110	0.015
spermatid development	GO:0007286	4	0.015
regulation of anatomical structure morphogenesis	GO:0022603	286	0.014
positive regulation of phosphorylation	GO:0042327	394	0.014
modification dependent macromolecule catabolic process	GO:0043632	212	0.014
negative regulation of cell death	GO:0060548	345	0.014
covalent chromatin modification	GO:0016569	254	0.014
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.014
compound eye development	GO:0048749	1	0.014
dna repair	GO:0006281	198	0.014
macromolecule methylation	GO:0043414	97	0.014
intracellular protein transport	GO:0006886	270	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.014
response to oxygen containing compound	GO:1901700	369	0.014
positive regulation of transport	GO:0051050	336	0.013
chemical homeostasis	GO:0048878	306	0.013
methylation	GO:0032259	106	0.013
cofactor metabolic process	GO:0051186	87	0.013
single organism membrane fusion	GO:0044801	37	0.013
regulation of cellular amine metabolic process	GO:0033238	11	0.012
sphingoid metabolic process	GO:0046519	8	0.012
monosaccharide metabolic process	GO:0005996	74	0.012
microtubule cytoskeleton organization	GO:0000226	176	0.012
purine ribonucleoside catabolic process	GO:0046130	398	0.012
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	156	0.012
endomembrane system organization	GO:0010256	196	0.012
positive regulation of cellular amine metabolic process	GO:0033240	7	0.012
regulation of homeostatic process	GO:0032844	121	0.012
immune response	GO:0006955	307	0.012
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.012
regulation of transferase activity	GO:0051338	355	0.012
response to dietary excess	GO:0002021	2	0.012
transmembrane transport	GO:0055085	399	0.012
protein targeting	GO:0006605	187	0.012
nervous system development	GO:0007399	293	0.012
microtubule based process	GO:0007017	210	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.012
cellular amide metabolic process	GO:0043603	69	0.011
positive regulation of cellular catabolic process	GO:0031331	284	0.011
mrna metabolic process	GO:0016071	175	0.011
regulation of protein localization	GO:0032880	296	0.011
regulation of cell division	GO:0051302	116	0.011
ubiquitin dependent protein catabolic process	GO:0006511	206	0.011
negative regulation of hydrolase activity	GO:0051346	182	0.011
regulation of cell cycle process	GO:0010564	266	0.011
ncrna metabolic process	GO:0034660	108	0.011
regulation of proteolysis	GO:0030162	293	0.011
ceramide metabolic process	GO:0006672	25	0.011
negative regulation of cellular protein metabolic process	GO:0032269	353	0.011
rna processing	GO:0006396	255	0.011
cell development	GO:0048468	328	0.011
protein oligomerization	GO:0051259	173	0.011
spermatid differentiation	GO:0048515	4	0.010
tripartite regional subdivision	GO:0007351	2	0.010
regulation of secretion by cell	GO:1903530	177	0.010
adult locomotory behavior	GO:0008344	1	0.010
regulation of protein catabolic process	GO:0042176	155	0.010
negative regulation of mitochondrion organization	GO:0010823	22	0.010
negative regulation of transport	GO:0051051	176	0.010
positive regulation of cellular component biogenesis	GO:0044089	158	0.010
regeneration	GO:0031099	4	0.010
regulation of establishment of protein localization	GO:0070201	242	0.010
rna splicing	GO:0008380	131	0.010

ATG4C disease predictions

Disease	DO term ID	Size	Probability
sensory system disease	DOID:0050155	203	0.056
nervous system disease	DOID:863	431	0.056
disease of metabolism	DOID:0014667	295	0.037
eye and adnexa disease	DOID:1492	150	0.035
eye disease	DOID:5614	149	0.035
inherited metabolic disorder	DOID:655	242	0.031
neuropathy	DOID:870	52	0.028
carbohydrate metabolic disorder	DOID:2978	55	0.023
musculoskeletal system disease	DOID:17	223	0.015
retinal disease	DOID:5679	118	0.012
immune system disease	DOID:2914	155	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network