| oxidation reduction process | GO:0055114 | 396 | 0.995 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.988 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.968 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.967 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.962 | |
| energy coupled proton transport down electrochemical gradient | GO:0015985 | 2 | 0.961 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.951 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.946 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.946 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.924 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.883 | |
| mating | GO:0007618 | 1 | 0.874 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.874 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.857 | |
| inorganic ion transmembrane transport | GO:0098660 | 231 | 0.856 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.847 | |
| post embryonic development | GO:0009791 | 2 | 0.826 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.816 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.815 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.801 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.792 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.788 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.780 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 79 | 0.768 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.758 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.757 | |
| cation transport | GO:0006812 | 331 | 0.752 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.748 | |
| hydrogen ion transmembrane transport | GO:1902600 | 15 | 0.722 | |
| atp catabolic process | GO:0006200 | 157 | 0.711 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.699 | |
| ribose phosphate biosynthetic process | GO:0046390 | 82 | 0.698 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.698 | |
| purine ribonucleoside biosynthetic process | GO:0046129 | 23 | 0.668 | |
| ribonucleotide biosynthetic process | GO:0009260 | 81 | 0.665 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.658 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.650 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.638 | |
| inorganic cation transmembrane transport | GO:0098662 | 194 | 0.624 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.598 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.582 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.579 | |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.576 | |
| atp synthesis coupled proton transport | GO:0015986 | 2 | 0.568 | |
| atp synthesis coupled electron transport | GO:0042773 | 4 | 0.556 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.543 | |
| lipid localization | GO:0010876 | 106 | 0.516 | |
| ribonucleoside biosynthetic process | GO:0042455 | 25 | 0.494 | |
| purine ribonucleoside triphosphate biosynthetic process | GO:0009206 | 11 | 0.440 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.430 | |
| purine nucleotide biosynthetic process | GO:0006164 | 84 | 0.430 | |
| atp biosynthetic process | GO:0006754 | 11 | 0.401 | |
| purine containing compound biosynthetic process | GO:0072522 | 88 | 0.395 | |
| purine ribonucleoside monophosphate biosynthetic process | GO:0009168 | 16 | 0.373 | |
| nervous system development | GO:0007399 | 293 | 0.349 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.331 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.317 | Fly |
| atp metabolic process | GO:0046034 | 176 | 0.317 | |
| hydrogen transport | GO:0006818 | 23 | 0.313 | |
| endocytosis | GO:0006897 | 159 | 0.309 | Fly |
| glycosyl compound biosynthetic process | GO:1901659 | 27 | 0.308 | |
| spermatid development | GO:0007286 | 4 | 0.273 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.268 | |
| purine nucleoside monophosphate biosynthetic process | GO:0009127 | 16 | 0.266 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.255 | |
| anion transport | GO:0006820 | 161 | 0.242 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.217 | |
| nucleoside triphosphate biosynthetic process | GO:0009142 | 20 | 0.206 | |
| ribonucleoside triphosphate biosynthetic process | GO:0009201 | 12 | 0.200 | |
| aging | GO:0007568 | 66 | 0.196 | |
| cellular respiration | GO:0045333 | 21 | 0.187 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.181 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.172 | |
| ion homeostasis | GO:0050801 | 230 | 0.171 | |
| membrane organization | GO:0061024 | 292 | 0.167 | |
| transmembrane transport | GO:0055085 | 399 | 0.165 | |
| spermatid differentiation | GO:0048515 | 4 | 0.162 | |
| cranial nerve development | GO:0021545 | 4 | 0.161 | |
| cellular homeostasis | GO:0019725 | 196 | 0.160 | |
| reproductive process | GO:0022414 | 106 | 0.160 | |
| nucleoside monophosphate biosynthetic process | GO:0009124 | 19 | 0.158 | |
| generation of precursor metabolites and energy | GO:0006091 | 68 | 0.158 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.137 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 43 | 0.124 | |
| phosphate ion transmembrane transport | GO:0035435 | 4 | 0.120 | |
| epithelium development | GO:0060429 | 227 | 0.115 | |
| maintenance of location | GO:0051235 | 112 | 0.114 | |
| purine nucleoside triphosphate biosynthetic process | GO:0009145 | 11 | 0.109 | |
| purine nucleoside biosynthetic process | GO:0042451 | 23 | 0.106 | |
| ribonucleoside monophosphate biosynthetic process | GO:0009156 | 17 | 0.103 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.093 | |
| system process | GO:0003008 | 349 | 0.092 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.091 | |
| embryo development | GO:0009790 | 123 | 0.088 | Worm |
| nucleoside biosynthetic process | GO:0009163 | 26 | 0.085 | |
| cation homeostasis | GO:0055080 | 189 | 0.083 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.078 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.076 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.074 | |
| lipid metabolic process | GO:0006629 | 381 | 0.072 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.070 | |
| negative regulation of transport | GO:0051051 | 176 | 0.067 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.066 | |
| chemical homeostasis | GO:0048878 | 306 | 0.066 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.065 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.060 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.059 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.059 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.057 | |
| pyruvate transmembrane transport | GO:1901475 | 1 | 0.056 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.054 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.053 | |
| behavior | GO:0007610 | 112 | 0.052 | |
| central nervous system development | GO:0007417 | 123 | 0.052 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.052 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.051 | |
| proton transport | GO:0015992 | 22 | 0.051 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.051 | |
| regeneration | GO:0031099 | 4 | 0.050 | |
| cell cell signaling | GO:0007267 | 155 | 0.049 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.048 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.048 | |
| tissue regeneration | GO:0042246 | 3 | 0.047 | |
| organic anion transport | GO:0015711 | 103 | 0.046 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.046 | |
| regulation of growth | GO:0040008 | 165 | 0.046 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.042 | |
| single organism reproductive process | GO:0044702 | 98 | 0.042 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.042 | |
| phototransduction | GO:0007602 | 3 | 0.041 | |
| cardiovascular system development | GO:0072358 | 262 | 0.041 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.038 | |
| defense response | GO:0006952 | 315 | 0.038 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.036 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.036 | |
| immune response | GO:0006955 | 307 | 0.036 | |
| head development | GO:0060322 | 108 | 0.035 | |
| response to hypoxia | GO:0001666 | 96 | 0.034 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.034 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.032 | |
| brain development | GO:0007420 | 97 | 0.031 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.030 | Worm |
| midbrain development | GO:0030901 | 45 | 0.029 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.029 | |
| protein processing | GO:0016485 | 226 | 0.028 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.028 | |
| sex differentiation | GO:0007548 | 45 | 0.028 | |
| response to other organism | GO:0051707 | 261 | 0.028 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.028 | |
| multi organism reproductive process | GO:0044703 | 54 | 0.028 | |
| regulation of ras gtpase activity | GO:0032318 | 128 | 0.027 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.027 | |
| electron transport chain | GO:0022900 | 8 | 0.027 | |
| nucleoside diphosphate metabolic process | GO:0009132 | 16 | 0.026 | |
| response to oxidative stress | GO:0006979 | 121 | 0.026 | |
| metal ion transport | GO:0030001 | 272 | 0.026 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.025 | |
| development of primary sexual characteristics | GO:0045137 | 35 | 0.025 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.024 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.024 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.024 | |
| substantia nigra development | GO:0021762 | 45 | 0.023 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.023 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.022 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.022 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.022 | |
| gonad development | GO:0008406 | 34 | 0.022 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.022 | |
| regulation of rab gtpase activity | GO:0032313 | 39 | 0.022 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.021 | |
| reproduction | GO:0000003 | 63 | 0.021 | |
| innate immune response | GO:0045087 | 178 | 0.021 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.020 | |
| negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | GO:1901029 | 4 | 0.020 | |
| circulatory system development | GO:0072359 | 262 | 0.020 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.019 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.019 | |
| reproductive system development | GO:0061458 | 56 | 0.019 | |
| epithelial cell differentiation | GO:0030855 | 141 | 0.018 | |
| lipid storage | GO:0019915 | 28 | 0.018 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.018 | |
| multicellular organismal reproductive process | GO:0048609 | 40 | 0.018 | |
| phosphate ion transport | GO:0006817 | 7 | 0.018 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.017 | |
| phagocytosis | GO:0006909 | 42 | 0.017 | Fly |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.017 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.017 | |
| calcium ion transport | GO:0006816 | 147 | 0.017 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.016 | |
| multicellular organismal response to stress | GO:0033555 | 1 | 0.016 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.016 | |
| regulation of mitochondrial membrane permeability involved in apoptotic process | GO:1902108 | 18 | 0.016 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.016 | |
| neural nucleus development | GO:0048857 | 47 | 0.016 | |
| neurogenesis | GO:0022008 | 169 | 0.016 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.016 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.015 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.015 | |
| female gamete generation | GO:0007292 | 2 | 0.015 | |
| lipid oxidation | GO:0034440 | 33 | 0.015 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.015 | |
| cell differentiation in spinal cord | GO:0021515 | 1 | 0.014 | |
| wound healing | GO:0042060 | 115 | 0.014 | |
| multi multicellular organism process | GO:0044706 | 18 | 0.014 | |
| osteoblast differentiation | GO:0001649 | 92 | 0.014 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.014 | |
| positive regulation of nucleotide biosynthetic process | GO:0030810 | 38 | 0.013 | |
| nerve development | GO:0021675 | 4 | 0.013 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.013 | |
| sexual reproduction | GO:0019953 | 37 | 0.013 | |
| response to bacterium | GO:0009617 | 144 | 0.013 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.013 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.013 | |
| regulation of protein processing | GO:0070613 | 150 | 0.013 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.013 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.012 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.012 | |
| regulation of protein localization | GO:0032880 | 296 | 0.012 | |
| organelle assembly | GO:0070925 | 176 | 0.012 | |
| angiogenesis | GO:0001525 | 147 | 0.012 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.012 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.012 | |
| protein maturation | GO:0051604 | 233 | 0.012 | |
| vasculature development | GO:0001944 | 181 | 0.012 | |
| gtp metabolic process | GO:0046039 | 239 | 0.012 | |
| amine metabolic process | GO:0009308 | 44 | 0.012 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.012 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.011 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.011 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.011 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.011 | |
| ventral spinal cord development | GO:0021517 | 1 | 0.011 | |
| growth | GO:0040007 | 202 | 0.011 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.011 | |
| single organism cellular localization | GO:1902580 | 332 | 0.011 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.011 | |
| oogenesis | GO:0048477 | 2 | 0.011 | |
| purine ribonucleoside diphosphate metabolic process | GO:0009179 | 3 | 0.011 | |
| optic nerve development | GO:0021554 | 2 | 0.011 | |
| synaptic transmission | GO:0007268 | 61 | 0.011 | |
| response to oxygen levels | GO:0070482 | 100 | 0.010 | |
| ribosome assembly | GO:0042255 | 9 | 0.010 | |
| endothelial cell proliferation | GO:0001935 | 65 | 0.010 | |
| regulation of neurogenesis | GO:0050767 | 82 | 0.010 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.010 | |