IMP: Integrative Multi-species Prediction

Homo sapiens

75 known processes

ATP5H

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d

(Aliases: ATPQ)

Ensembl: ENSG00000167863
HPRD: 16519
HGNC: 845
Entrez: 10476
UniProtKB: O75947
UniProtKB: A0PJH2

Process Predictions
Disease Predictions

ATP5H biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
atp metabolic process	GO:0046034	176	0.786
inorganic ion transmembrane transport	GO:0098660	231	0.754
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.753
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.740
purine ribonucleoside metabolic process	GO:0046128	437	0.718
inorganic cation transmembrane transport	GO:0098662	194	0.622
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.615
nucleoside triphosphate metabolic process	GO:0009141	422	0.610
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.606
post embryonic development	GO:0009791	2	0.584	Worm
ion transmembrane transport	GO:0034220	338	0.549
nucleoside monophosphate metabolic process	GO:0009123	191	0.526
proton transport	GO:0015992	22	0.517
hydrogen transport	GO:0006818	23	0.508
purine ribonucleotide biosynthetic process	GO:0009152	79	0.507
hydrogen ion transmembrane transport	GO:1902600	15	0.488
ribonucleoside catabolic process	GO:0042454	406	0.447
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.397
ribonucleotide biosynthetic process	GO:0009260	81	0.380
monovalent inorganic cation transport	GO:0015672	128	0.352
ribose phosphate biosynthetic process	GO:0046390	82	0.345
purine ribonucleoside biosynthetic process	GO:0046129	23	0.344
purine ribonucleoside catabolic process	GO:0046130	398	0.333
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.332
atp catabolic process	GO:0006200	157	0.320
organonitrogen compound biosynthetic process	GO:1901566	200	0.313
multicellular organismal aging	GO:0010259	3	0.308	Worm
carbohydrate derivative biosynthetic process	GO:1901137	207	0.305
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.269
purine nucleotide biosynthetic process	GO:0006164	84	0.256
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.244
cation transmembrane transport	GO:0098655	238	0.238
determination of adult lifespan	GO:0008340	2	0.227	Worm
mating	GO:0007618	1	0.216
nucleoside catabolic process	GO:0009164	408	0.215
nucleoside triphosphate catabolic process	GO:0009143	394	0.211
purine containing compound biosynthetic process	GO:0072522	88	0.211
energy coupled proton transport down electrochemical gradient	GO:0015985	2	0.208
nucleoside biosynthetic process	GO:0009163	26	0.207
purine ribonucleotide catabolic process	GO:0009154	404	0.198
ribonucleoside biosynthetic process	GO:0042455	25	0.198
organophosphate biosynthetic process	GO:0090407	163	0.198
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.194
cation transport	GO:0006812	331	0.192
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.189
atp biosynthetic process	GO:0006754	11	0.174
nucleotide catabolic process	GO:0009166	408	0.172
purine nucleoside biosynthetic process	GO:0042451	23	0.159
purine nucleotide catabolic process	GO:0006195	405	0.155
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	16	0.154
nucleoside phosphate biosynthetic process	GO:1901293	109	0.148
nucleoside phosphate catabolic process	GO:1901292	412	0.146
purine nucleoside monophosphate biosynthetic process	GO:0009127	16	0.125
purine containing compound catabolic process	GO:0072523	411	0.119
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.106
purine nucleoside catabolic process	GO:0006152	398	0.106
glycosyl compound catabolic process	GO:1901658	413	0.101
lipid metabolic process	GO:0006629	381	0.091
embryo development	GO:0009790	123	0.088	Worm
transmembrane transport	GO:0055085	399	0.088
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.083
endocytosis	GO:0006897	159	0.079
nucleoside monophosphate catabolic process	GO:0009125	159	0.077
organophosphate catabolic process	GO:0046434	430	0.072
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	11	0.066
generation of precursor metabolites and energy	GO:0006091	68	0.064
glycosyl compound biosynthetic process	GO:1901659	27	0.060
fatty acid metabolic process	GO:0006631	115	0.059
negative regulation of cell proliferation	GO:0008285	228	0.055
response to oxidative stress	GO:0006979	121	0.050
ribonucleotide catabolic process	GO:0009261	405	0.046
vesicle mediated transport	GO:0016192	371	0.046
head development	GO:0060322	108	0.045
atp synthesis coupled electron transport	GO:0042773	4	0.043
nucleotide biosynthetic process	GO:0009165	109	0.043
ribonucleoside triphosphate biosynthetic process	GO:0009201	12	0.043
oogenesis	GO:0048477	2	0.041
oxidation reduction process	GO:0055114	396	0.040
atp synthesis coupled proton transport	GO:0015986	2	0.038
nervous system development	GO:0007399	293	0.037
ribonucleoside monophosphate biosynthetic process	GO:0009156	17	0.037
immune response	GO:0006955	307	0.030
substantia nigra development	GO:0021762	45	0.029
purine nucleoside triphosphate biosynthetic process	GO:0009145	11	0.029
regulation of neuroblast proliferation	GO:1902692	3	0.028
cellular macromolecular complex assembly	GO:0034622	324	0.027
protein oligomerization	GO:0051259	173	0.027
central nervous system development	GO:0007417	123	0.027
neuroblast proliferation	GO:0007405	4	0.026
positive regulation of nucleotide metabolic process	GO:0045981	230	0.025
brain development	GO:0007420	97	0.024
midbrain development	GO:0030901	45	0.024
regulation of neural precursor cell proliferation	GO:2000177	4	0.023
lipid localization	GO:0010876	106	0.023
regulation of neurogenesis	GO:0050767	82	0.023
aging	GO:0007568	66	0.022	Worm
regulation of cellular amino acid metabolic process	GO:0006521	6	0.022
regulation of protein processing	GO:0070613	150	0.022
cellular homeostasis	GO:0019725	196	0.021
regulation of growth	GO:0040008	165	0.021
ion homeostasis	GO:0050801	230	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.021
regulation of gtp catabolic process	GO:0033124	180	0.021
cellular amino acid metabolic process	GO:0006520	116	0.021
cell development	GO:0048468	328	0.020
nucleoside monophosphate biosynthetic process	GO:0009124	19	0.020
myosin filament assembly	GO:0031034	2	0.020
cellular amine metabolic process	GO:0044106	41	0.020
regulation of cellular amine metabolic process	GO:0033238	11	0.019
behavior	GO:0007610	112	0.019
regulation of cell development	GO:0060284	161	0.019
negative regulation of cell differentiation	GO:0045596	171	0.019
regulation of epithelial cell proliferation	GO:0050678	113	0.019
maintenance of location	GO:0051235	112	0.019
positive regulation of developmental process	GO:0051094	314	0.018
female gamete generation	GO:0007292	2	0.018
regulation of nucleotide metabolic process	GO:0006140	269	0.018
system process	GO:0003008	349	0.018
negative regulation of hydrolase activity	GO:0051346	182	0.018
regulation of purine nucleotide metabolic process	GO:1900542	264	0.018
regulation of cell cycle	GO:0051726	393	0.017
regulation of cellular ketone metabolic process	GO:0010565	50	0.017
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.017
reproduction	GO:0000003	63	0.017	Worm
energy derivation by oxidation of organic compounds	GO:0015980	43	0.016
mitochondrial respiratory chain complex assembly	GO:0033108	23	0.016
cellular chemical homeostasis	GO:0055082	180	0.016
mitochondrion organization	GO:0007005	156	0.016
receptor mediated endocytosis	GO:0006898	84	0.016
cellular protein complex assembly	GO:0043623	188	0.016
positive regulation of cellular component organization	GO:0051130	376	0.016
inorganic anion transmembrane transport	GO:0098661	47	0.015
actin cytoskeleton organization	GO:0030036	207	0.015
guanosine containing compound metabolic process	GO:1901068	244	0.015
chemical homeostasis	GO:0048878	306	0.015
mitochondrial respiratory chain complex i biogenesis	GO:0097031	16	0.015
protein maturation	GO:0051604	233	0.015
regulation of membrane potential	GO:0042391	95	0.015
membrane organization	GO:0061024	292	0.015
nitrogen compound transport	GO:0071705	191	0.015
regulation of cell differentiation	GO:0045595	393	0.015
embryo development ending in birth or egg hatching	GO:0009792	34	0.014	Worm
spermatid differentiation	GO:0048515	4	0.014
positive regulation of organelle organization	GO:0010638	195	0.014
cellular lipid metabolic process	GO:0044255	303	0.014
epithelial cell proliferation	GO:0050673	128	0.014
regulation of cellular response to stress	GO:0080135	244	0.014
gtp metabolic process	GO:0046039	239	0.014
reactive oxygen species biosynthetic process	GO:1903409	4	0.013
divalent metal ion transport	GO:0070838	152	0.013
mitochondrial atp synthesis coupled electron transport	GO:0042775	4	0.013
epithelium development	GO:0060429	227	0.013
negative regulation of cellular protein metabolic process	GO:0032269	353	0.013
positive regulation of immune response	GO:0050778	159	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.013
negative regulation of developmental process	GO:0051093	247	0.013
locomotory behavior	GO:0007626	1	0.013
cytokine production	GO:0001816	247	0.013
gtp catabolic process	GO:0006184	237	0.013
growth	GO:0040007	202	0.013
developmental process involved in reproduction	GO:0003006	66	0.013	Worm
regulation of lipid metabolic process	GO:0019216	96	0.012
cellular protein catabolic process	GO:0044257	261	0.012
protein localization to membrane	GO:0072657	160	0.012
positive regulation of cellular amine metabolic process	GO:0033240	7	0.012
calcium ion transport	GO:0006816	147	0.012
negative regulation of multicellular organismal process	GO:0051241	317	0.012
organelle assembly	GO:0070925	176	0.012
protein processing	GO:0016485	226	0.012
cellular ketone metabolic process	GO:0042180	80	0.012
metal ion homeostasis	GO:0055065	169	0.012
mitotic cell cycle	GO:0000278	326	0.012
microtubule cytoskeleton organization	GO:0000226	176	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	128	0.012
response to abiotic stimulus	GO:0009628	336	0.012
regulation of immune response	GO:0050776	201	0.012
actin filament based process	GO:0030029	224	0.011
neuromuscular junction development	GO:0007528	3	0.011
regulation of nervous system development	GO:0051960	88	0.011
negative regulation of protein metabolic process	GO:0051248	391	0.011
defense response	GO:0006952	315	0.011
amine metabolic process	GO:0009308	44	0.011
neural nucleus development	GO:0048857	47	0.011
innate immune response	GO:0045087	178	0.011
organic acid biosynthetic process	GO:0016053	97	0.011
neurogenesis	GO:0022008	169	0.011
myosin filament organization	GO:0031033	2	0.011
spinal cord development	GO:0021510	4	0.011
negative regulation of cell development	GO:0010721	48	0.011
tissue regeneration	GO:0042246	3	0.011
regulation of ras gtpase activity	GO:0032318	128	0.011
cellular component morphogenesis	GO:0032989	314	0.011
modification dependent macromolecule catabolic process	GO:0043632	212	0.011
regulation of gtpase activity	GO:0043087	180	0.010
regulation of transferase activity	GO:0051338	355	0.010
negative regulation of apoptotic process	GO:0043066	316	0.010

ATP5H disease predictions

Disease	DO term ID	Size	Probability
inherited metabolic disorder	DOID:655	242	0.057
disease of metabolism	DOID:0014667	295	0.057
nervous system disease	DOID:863	431	0.041
central nervous system disease	DOID:331	186	0.041
leigh disease	DOID:3652	16	0.022
mitochondrial metabolism disease	DOID:700	29	0.022
disease of cellular proliferation	DOID:14566	174	0.016
cancer	DOID:162	167	0.016
organ system cancer	DOID:0050686	164	0.011

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