| positive regulation of release of cytochrome c from mitochondria | GO:0090200 | 18 | 1.000 | |
| regulation of release of cytochrome c from mitochondria | GO:0090199 | 29 | 1.000 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 28 | 1.000 | |
| positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | GO:1901030 | 3 | 1.000 | |
| release of cytochrome c from mitochondria | GO:0001836 | 35 | 1.000 | |
| regulation of protein oligomerization | GO:0032459 | 26 | 1.000 | |
| positive regulation of mitochondrion organization | GO:0010822 | 30 | 1.000 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 1.000 | |
| positive regulation of protein oligomerization | GO:0032461 | 17 | 1.000 | |
| regulation of oxidative stress induced neuron death | GO:1903203 | 9 | 0.999 | |
| neuron death in response to oxidative stress | GO:0036475 | 9 | 0.999 | |
| regulation of mitochondrion organization | GO:0010821 | 54 | 0.999 | |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001240 | 16 | 0.999 | |
| protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | GO:0001844 | 2 | 0.999 | |
| positive regulation of oxidative stress induced cell death | GO:1903209 | 5 | 0.998 | |
| regulation of mitochondrial membrane permeability involved in apoptotic process | GO:1902108 | 18 | 0.997 | Mouse |
| mitochondrial membrane organization | GO:0007006 | 40 | 0.996 | Mouse |
| positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902177 | 4 | 0.996 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.996 | |
| regulation of membrane permeability | GO:0090559 | 25 | 0.995 | Mouse |
| zymogen activation | GO:0031638 | 70 | 0.994 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.994 | |
| positive regulation of endoplasmic reticulum unfolded protein response | GO:1900103 | 4 | 0.993 | |
| modulation by virus of host morphology or physiology | GO:0019048 | 10 | 0.992 | Mouse |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.991 | Mouse |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 20 | 0.990 | |
| positive regulation of response to oxidative stress | GO:1902884 | 7 | 0.990 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.990 | |
| regulation of mitochondrial membrane permeability | GO:0046902 | 25 | 0.989 | Mouse |
| regulation of peptidase activity | GO:0052547 | 180 | 0.989 | |
| positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway | GO:1903378 | 2 | 0.988 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.988 | |
| mitochondrial transport | GO:0006839 | 60 | 0.987 | Mouse |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.982 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.981 | |
| positive regulation of mitochondrial membrane permeability | GO:0035794 | 17 | 0.980 | Mouse |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.978 | |
| modulation by symbiont of host apoptotic process | GO:0052150 | 1 | 0.978 | Mouse |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.976 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.974 | |
| positive regulation of protein homooligomerization | GO:0032464 | 7 | 0.971 | |
| regulation of execution phase of apoptosis | GO:1900117 | 11 | 0.970 | |
| mitochondrial outer membrane permeabilization | GO:0097345 | 15 | 0.970 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.970 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 22 | 0.970 | Mouse |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.969 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.965 | |
| mitochondrial outer membrane permeabilization involved in programmed cell death | GO:1902686 | 16 | 0.964 | Mouse |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.963 | |
| mitochondrial fragmentation involved in apoptotic process | GO:0043653 | 7 | 0.962 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.960 | |
| modulation of programmed cell death in other organism involved in symbiotic interaction | GO:0052248 | 1 | 0.960 | Mouse |
| protein homooligomerization | GO:0051260 | 100 | 0.957 | |
| neuron intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0036480 | 7 | 0.954 | |
| regulation of endoplasmic reticulum unfolded protein response | GO:1900101 | 5 | 0.953 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.951 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.948 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.948 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 21 | 0.947 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.945 | |
| positive regulation of cellular response to oxidative stress | GO:1900409 | 7 | 0.944 | |
| modulation of programmed cell death in other organism | GO:0044531 | 1 | 0.941 | Mouse |
| modulation of apoptotic process in other organism | GO:0044532 | 1 | 0.940 | Mouse |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.940 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.940 | |
| modification by symbiont of host morphology or physiology | GO:0044003 | 12 | 0.936 | Mouse |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.936 | |
| protein processing | GO:0016485 | 226 | 0.930 | |
| defense response to virus | GO:0051607 | 71 | 0.928 | |
| modulation by organism of apoptotic process in other organism involved in symbiotic interaction | GO:0052433 | 1 | 0.926 | Mouse |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.925 | |
| establishment of protein localization to mitochondrion | GO:0072655 | 22 | 0.924 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 8 | 0.923 | Mouse |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.923 | |
| protein insertion into mitochondrial membrane | GO:0051204 | 3 | 0.923 | |
| lymphocyte homeostasis | GO:0002260 | 4 | 0.921 | Mouse |
| t cell homeostasis | GO:0043029 | 3 | 0.921 | Mouse |
| regulation of cellular ph reduction | GO:0032847 | 1 | 0.920 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.915 | |
| modulation by symbiont of host cellular process | GO:0044068 | 3 | 0.908 | Mouse |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.905 | |
| regulation of response to oxidative stress | GO:1902882 | 26 | 0.902 | |
| regulation of protein heterodimerization activity | GO:0043497 | 5 | 0.902 | |
| membrane organization | GO:0061024 | 292 | 0.901 | Mouse |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.899 | |
| regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902175 | 16 | 0.896 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.895 | |
| regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway | GO:1903376 | 7 | 0.893 | |
| mitochondrion organization | GO:0007005 | 156 | 0.893 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.891 | |
| cation homeostasis | GO:0055080 | 189 | 0.889 | |
| execution phase of apoptosis | GO:0097194 | 32 | 0.888 | |
| signal transduction in absence of ligand | GO:0038034 | 22 | 0.883 | Mouse |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.881 | |
| modulation by virus of host process | GO:0019054 | 2 | 0.874 | Mouse |
| single organism membrane fusion | GO:0044801 | 37 | 0.866 | |
| mitochondrial fission | GO:0000266 | 14 | 0.863 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.862 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c | GO:0008635 | 2 | 0.862 | |
| protein oligomerization | GO:0051259 | 173 | 0.862 | |
| monovalent inorganic cation homeostasis | GO:0055067 | 37 | 0.861 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.859 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.856 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.853 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 24 | 0.852 | |
| calcium ion transport | GO:0006816 | 147 | 0.850 | |
| regulation of mitochondrial fusion | GO:0010635 | 5 | 0.844 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.844 | |
| fibroblast proliferation | GO:0048144 | 33 | 0.842 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.841 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 26 | 0.841 | |
| negative regulation of anoikis | GO:2000811 | 15 | 0.835 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.834 | |
| protein maturation | GO:0051604 | 233 | 0.833 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.827 | |
| regulation of immune response | GO:0050776 | 201 | 0.823 | |
| cellular homeostasis | GO:0019725 | 196 | 0.814 | |
| regulation of protein localization to plasma membrane | GO:1903076 | 40 | 0.812 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.807 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.805 | |
| apoptotic process involved in morphogenesis | GO:0060561 | 3 | 0.789 | Mouse |
| modulation by symbiont of host programmed cell death | GO:0052040 | 1 | 0.782 | Mouse |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 42 | 0.778 | |
| positive regulation of apoptotic process involved in mammary gland involution | GO:0060058 | 1 | 0.776 | |
| regulation of apoptotic dna fragmentation | GO:1902510 | 3 | 0.776 | |
| response to nicotine | GO:0035094 | 12 | 0.774 | |
| negative regulation of execution phase of apoptosis | GO:1900118 | 6 | 0.772 | |
| positive regulation of apoptotic process involved in morphogenesis | GO:1902339 | 1 | 0.769 | |
| defense response to other organism | GO:0098542 | 129 | 0.764 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.764 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.757 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 26 | 0.756 | |
| regulation of protein localization | GO:0032880 | 296 | 0.754 | |
| neuron apoptotic process | GO:0051402 | 39 | 0.754 | Mouse |
| immune response activating signal transduction | GO:0002757 | 90 | 0.749 | |
| single organism membrane organization | GO:0044802 | 268 | 0.746 | Mouse |
| cellular cation homeostasis | GO:0030003 | 163 | 0.737 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.737 | |
| positive regulation of execution phase of apoptosis | GO:1900119 | 5 | 0.730 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.721 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.715 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.708 | |
| regulation of mitochondrial membrane potential | GO:0051881 | 23 | 0.700 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.695 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 0.691 | |
| activation of immune response | GO:0002253 | 114 | 0.688 | |
| mitochondrial fusion | GO:0008053 | 13 | 0.683 | |
| protein localization to membrane | GO:0072657 | 160 | 0.682 | |
| positive regulation of mitochondrial membrane permeability involved in apoptotic process | GO:1902110 | 16 | 0.676 | Mouse |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.675 | |
| positive regulation of oxidative stress induced neuron death | GO:1903223 | 2 | 0.670 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.661 | |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.658 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.653 | |
| establishment of protein localization to membrane | GO:0090150 | 121 | 0.651 | |
| regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | GO:1901028 | 9 | 0.651 | |
| response to alkaloid | GO:0043279 | 20 | 0.646 | |
| lymphocyte apoptotic process | GO:0070227 | 20 | 0.646 | Mouse |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902043 | 3 | 0.644 | |
| response to hypoxia | GO:0001666 | 96 | 0.641 | |
| protein insertion into membrane | GO:0051205 | 9 | 0.635 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.634 | |
| single organism cellular localization | GO:1902580 | 332 | 0.633 | |
| modification of morphology or physiology of other organism | GO:0035821 | 43 | 0.629 | Mouse |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.623 | |
| membrane fusion | GO:0061025 | 43 | 0.619 | |
| positive regulation of neuron death | GO:1901216 | 14 | 0.618 | Mouse |
| organelle fusion | GO:0048284 | 36 | 0.617 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.607 | |
| response to uv | GO:0009411 | 73 | 0.604 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.603 | |
| negative regulation of signal transduction in absence of ligand | GO:1901099 | 16 | 0.596 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.594 | |
| transformed cell apoptotic process | GO:0006927 | 3 | 0.590 | |
| retinal cell apoptotic process | GO:1990009 | 1 | 0.586 | |
| regulation of ion homeostasis | GO:2000021 | 73 | 0.582 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.578 | |
| negative regulation of calcium ion transport into cytosol | GO:0010523 | 3 | 0.570 | |
| metal ion transport | GO:0030001 | 272 | 0.570 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.569 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.568 | |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | GO:0070059 | 12 | 0.564 | Zebrafish |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.562 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.562 | |
| post embryonic development | GO:0009791 | 2 | 0.560 | Mouse |
| protein localization to organelle | GO:0033365 | 280 | 0.559 | |
| response to unfolded protein | GO:0006986 | 24 | 0.558 | |
| gtp metabolic process | GO:0046039 | 239 | 0.554 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.553 | |
| ion homeostasis | GO:0050801 | 230 | 0.548 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.547 | |
| negative regulation of mitochondrion organization | GO:0010823 | 22 | 0.542 | |
| negative regulation of binding | GO:0051100 | 57 | 0.540 | |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.538 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 48 | 0.538 | |
| cellular response to uv | GO:0034644 | 32 | 0.537 | |
| negative regulation by symbiont of host programmed cell death | GO:0052041 | 1 | 0.536 | |
| regulation of protein binding | GO:0043393 | 66 | 0.533 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.525 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.520 | |
| cell death in response to oxidative stress | GO:0036473 | 29 | 0.506 | |
| protein ubiquitination | GO:0016567 | 314 | 0.504 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.502 | |
| cation transport | GO:0006812 | 331 | 0.500 | |
| cellular component disassembly | GO:0022411 | 92 | 0.499 | |
| positive regulation of developmental pigmentation | GO:0048087 | 2 | 0.485 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.482 | |
| response to virus | GO:0009615 | 126 | 0.477 | Mouse |
| gtp catabolic process | GO:0006184 | 237 | 0.461 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.461 | |
| regulation of neuron death | GO:1901214 | 56 | 0.459 | Mouse |
| patterning of blood vessels | GO:0001569 | 2 | 0.457 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.455 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.455 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.447 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.446 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.444 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.444 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.440 | Mouse |
| response to radiation | GO:0009314 | 151 | 0.439 | |
| regulation of sequestering of calcium ion | GO:0051282 | 41 | 0.438 | |
| transmembrane transport | GO:0055085 | 399 | 0.436 | |
| viral process | GO:0016032 | 146 | 0.424 | Mouse |
| anoikis | GO:0043276 | 22 | 0.423 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.422 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.418 | |
| regulation of ion transport | GO:0043269 | 189 | 0.416 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.416 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.412 | |
| positive regulation of dna catabolic process | GO:1903626 | 2 | 0.411 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.408 | |
| defense response | GO:0006952 | 315 | 0.405 | |
| response to salt stress | GO:0009651 | 3 | 0.401 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.400 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.400 | |
| negative regulation by symbiont of host apoptotic process | GO:0033668 | 1 | 0.400 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.398 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.396 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.394 | Mouse |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.390 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 46 | 0.384 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 40 | 0.378 | |
| regulation of cellular ph | GO:0030641 | 17 | 0.371 | |
| establishment or maintenance of transmembrane electrochemical gradient | GO:0010248 | 2 | 0.370 | |
| plasma membrane organization | GO:0007009 | 115 | 0.367 | |
| protein catabolic process | GO:0030163 | 325 | 0.361 | |
| regulation of transmembrane transport | GO:0034762 | 139 | 0.358 | |
| negative regulation of establishment of protein localization to plasma membrane | GO:0090005 | 9 | 0.358 | |
| behavioral defense response | GO:0002209 | 0 | 0.355 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.354 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.352 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.346 | |
| response to other organism | GO:0051707 | 261 | 0.340 | Mouse |
| response to metal ion | GO:0010038 | 84 | 0.339 | |
| dna catabolic process endonucleolytic | GO:0000737 | 37 | 0.339 | |
| regulation of anoikis | GO:2000209 | 19 | 0.339 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.338 | Mouse |
| negative regulation of neuron apoptotic process | GO:0043524 | 23 | 0.337 | |
| regulation of neuron apoptotic process | GO:0043523 | 35 | 0.332 | Mouse |
| b cell proliferation | GO:0042100 | 22 | 0.332 | |
| negative regulation of response to dna damage stimulus | GO:2001021 | 33 | 0.331 | |
| endomembrane system organization | GO:0010256 | 196 | 0.330 | |
| antigen receptor mediated signaling pathway | GO:0050851 | 38 | 0.329 | |
| regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902041 | 24 | 0.328 | |
| protein localization to mitochondrion | GO:0070585 | 25 | 0.328 | |
| modulation by virus of host apoptotic process | GO:0039526 | 1 | 0.327 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.322 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 54 | 0.320 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.317 | |
| negative regulation of endoplasmic reticulum calcium ion concentration | GO:0032471 | 6 | 0.308 | |
| positive regulation of b cell activation | GO:0050871 | 17 | 0.301 | |
| cellular carbohydrate metabolic process | GO:0044262 | 84 | 0.299 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.296 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.296 | Mouse |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.294 | |
| positive regulation of apoptotic dna fragmentation | GO:1902512 | 1 | 0.290 | |
| cytokinesis | GO:0000910 | 96 | 0.285 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.285 | Mouse |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.283 | |
| sequestering of calcium ion | GO:0051208 | 17 | 0.282 | |
| negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction | GO:0052490 | 1 | 0.281 | |
| immune effector process | GO:0002252 | 159 | 0.280 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.279 | |
| release of matrix enzymes from mitochondria | GO:0032976 | 1 | 0.275 | |
| regulation of binding | GO:0051098 | 111 | 0.275 | |
| urogenital system development | GO:0001655 | 65 | 0.274 | Mouse |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.270 | |
| immune response | GO:0006955 | 307 | 0.269 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.268 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.266 | |
| ph reduction | GO:0045851 | 11 | 0.266 | |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.265 | |
| cellular response to radiation | GO:0071478 | 65 | 0.264 | |
| growth | GO:0040007 | 202 | 0.261 | Mouse |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.261 | |
| head development | GO:0060322 | 108 | 0.257 | |
| regulation of protein homodimerization activity | GO:0043496 | 9 | 0.257 | |
| nervous system development | GO:0007399 | 293 | 0.257 | |
| cardiovascular system development | GO:0072358 | 262 | 0.256 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.254 | |
| fear response | GO:0042596 | 0 | 0.254 | |
| neuron death | GO:0070997 | 65 | 0.252 | Mouse |
| lymphocyte activation | GO:0046649 | 133 | 0.251 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 82 | 0.249 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.248 | |
| multi organism cellular process | GO:0044764 | 156 | 0.244 | Mouse |
| response to oxidative stress | GO:0006979 | 121 | 0.243 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.241 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.241 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.239 | |
| positive regulation of transport | GO:0051050 | 336 | 0.239 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.239 | |
| cell division | GO:0051301 | 168 | 0.237 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.235 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.235 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.233 | |
| regulation of developmental pigmentation | GO:0048070 | 2 | 0.230 | Mouse |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.229 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.228 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.227 | |
| modification of morphology or physiology of other organism involved in symbiotic interaction | GO:0051817 | 38 | 0.227 | Mouse |
| cellular response to decreased oxygen levels | GO:0036294 | 51 | 0.224 | |
| chemical homeostasis | GO:0048878 | 306 | 0.223 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.223 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.217 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.217 | |
| response to axon injury | GO:0048678 | 1 | 0.216 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.215 | |
| limbic system development | GO:0021761 | 3 | 0.211 | |
| positive regulation of b cell proliferation | GO:0030890 | 12 | 0.211 | |
| response to mechanical stimulus | GO:0009612 | 51 | 0.211 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.210 | |
| cellular response to topologically incorrect protein | GO:0035967 | 19 | 0.209 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.208 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.207 | |
| regulation of intracellular ph | GO:0051453 | 16 | 0.206 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.206 | |
| cellular response to nutrient levels | GO:0031669 | 69 | 0.205 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.204 | |
| neural tube patterning | GO:0021532 | 2 | 0.204 | |
| negative regulation of neuron death | GO:1901215 | 32 | 0.200 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.200 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.200 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.197 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.197 | |
| positive regulation of mononuclear cell proliferation | GO:0032946 | 47 | 0.197 | |
| response to inorganic substance | GO:0010035 | 127 | 0.194 | |
| female gamete generation | GO:0007292 | 2 | 0.191 | |
| cellular response to starvation | GO:0009267 | 58 | 0.190 | |
| regulation of cell activation | GO:0050865 | 125 | 0.189 | |
| protein localization to plasma membrane | GO:0072659 | 93 | 0.188 | |
| regulation of apoptotic process involved in morphogenesis | GO:1902337 | 1 | 0.188 | |
| cytosolic calcium ion transport | GO:0060401 | 48 | 0.187 | |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.185 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.184 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.182 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.182 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:2001269 | 1 | 0.182 | |
| apoptotic dna fragmentation | GO:0006309 | 6 | 0.178 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.178 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.177 | Mouse |
| oxidation reduction process | GO:0055114 | 396 | 0.176 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.175 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.174 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.174 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.173 | |
| regulation of cell growth | GO:0001558 | 135 | 0.172 | |
| cellular response to light stimulus | GO:0071482 | 34 | 0.168 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.168 | Mouse |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.168 | |
| regulation of cell development | GO:0060284 | 161 | 0.166 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.165 | |
| tube development | GO:0035295 | 125 | 0.164 | Mouse |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.163 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.163 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.162 | |
| regulation of intrinsic apoptotic signaling pathway in response to dna damage | GO:1902229 | 20 | 0.161 | |
| apoptotic nuclear changes | GO:0030262 | 13 | 0.160 | |
| b cell apoptotic process | GO:0001783 | 6 | 0.160 | Mouse |
| calcium ion homeostasis | GO:0055074 | 122 | 0.158 | |
| ossification | GO:0001503 | 121 | 0.155 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.154 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.154 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.154 | |
| response to drug | GO:0042493 | 81 | 0.153 | |
| response to oxygen levels | GO:0070482 | 100 | 0.151 | |
| signal transduction in response to dna damage | GO:0042770 | 57 | 0.150 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.149 | |
| positive regulation of lymphocyte activation | GO:0051251 | 73 | 0.148 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.147 | |
| regeneration | GO:0031099 | 4 | 0.147 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.146 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.146 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.145 | |
| post embryonic organ development | GO:0048569 | 1 | 0.144 | Mouse |
| response to starvation | GO:0042594 | 59 | 0.143 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.143 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.143 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.142 | |
| b cell receptor signaling pathway | GO:0050853 | 18 | 0.141 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.141 | |
| kidney development | GO:0001822 | 53 | 0.140 | Mouse |
| regulation of fibroblast proliferation | GO:0048145 | 32 | 0.140 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.139 | |
| positive regulation of cell growth | GO:0030307 | 48 | 0.138 | |
| cellular component disassembly involved in execution phase of apoptosis | GO:0006921 | 13 | 0.137 | |
| suppression by virus of host apoptotic process | GO:0019050 | 1 | 0.137 | |
| regulation of lymphocyte apoptotic process | GO:0070228 | 15 | 0.136 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.134 | |
| tube morphogenesis | GO:0035239 | 95 | 0.134 | Mouse |
| hypothalamus development | GO:0021854 | 1 | 0.133 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.133 | |
| regulation of calcium ion transport into cytosol | GO:0010522 | 33 | 0.132 | |
| positive regulation of glucose metabolic process | GO:0010907 | 12 | 0.132 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.131 | |
| response to transition metal nanoparticle | GO:1990267 | 29 | 0.130 | |
| regulation of b cell apoptotic process | GO:0002902 | 5 | 0.126 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.123 | |
| regulation of b cell proliferation | GO:0030888 | 18 | 0.120 | |
| regulation of protein processing | GO:0070613 | 150 | 0.119 | |
| regulation of ph | GO:0006885 | 20 | 0.119 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 47 | 0.119 | |
| positive regulation of carbohydrate metabolic process | GO:0045913 | 21 | 0.119 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.118 | |
| response to cytokine | GO:0034097 | 232 | 0.118 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.116 | |
| oogenesis | GO:0048477 | 2 | 0.116 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.114 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.114 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.113 | |
| response to topologically incorrect protein | GO:0035966 | 29 | 0.112 | |
| leukocyte homeostasis | GO:0001776 | 7 | 0.111 | Mouse |
| cell activation | GO:0001775 | 213 | 0.111 | |
| regulation of glucose metabolic process | GO:0010906 | 28 | 0.111 | |
| monosaccharide metabolic process | GO:0005996 | 74 | 0.111 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.110 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.110 | |
| central nervous system development | GO:0007417 | 123 | 0.110 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.109 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.107 | |
| positive regulation of leukocyte activation | GO:0002696 | 80 | 0.106 | |
| pigment granule organization | GO:0048753 | 7 | 0.106 | |
| negative regulation of fibroblast proliferation | GO:0048147 | 12 | 0.105 | |
| positive regulation of dna damage response signal transduction by p53 class mediator | GO:0043517 | 8 | 0.105 | |
| chordate embryonic development | GO:0043009 | 34 | 0.105 | Mouse |
| negative regulation of sequestering of calcium ion | GO:0051283 | 41 | 0.102 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.101 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.100 | |
| positive regulation of b cell apoptotic process | GO:0002904 | 1 | 0.098 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.096 | |
| negative regulation of protein binding | GO:0032091 | 35 | 0.096 | |
| dna catabolic process | GO:0006308 | 49 | 0.095 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.094 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.093 | |
| hexose metabolic process | GO:0019318 | 55 | 0.092 | |
| regulation of b cell activation | GO:0050864 | 24 | 0.092 | |
| regulation of growth | GO:0040008 | 165 | 0.091 | Mouse |
| apoptotic process involved in mammary gland involution | GO:0060057 | 1 | 0.091 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.090 | |
| interaction with host | GO:0051701 | 42 | 0.089 | Mouse |
| vasculature development | GO:0001944 | 181 | 0.088 | |
| embryonic morphogenesis | GO:0048598 | 85 | 0.087 | Mouse |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.087 | |
| regulation of protein homooligomerization | GO:0032462 | 11 | 0.084 | |
| t cell activation | GO:0042110 | 99 | 0.084 | |
| cerebral cortex development | GO:0021987 | 10 | 0.084 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.084 | |
| cellular response to extracellular stimulus | GO:0031668 | 72 | 0.083 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.083 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.083 | |
| b cell receptor apoptotic signaling pathway | GO:1990117 | 1 | 0.082 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.081 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.081 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 41 | 0.081 | |
| brain development | GO:0007420 | 97 | 0.080 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.079 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.079 | |
| intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator | GO:0042771 | 23 | 0.079 | |
| spermatid differentiation | GO:0048515 | 4 | 0.078 | |
| response to iron ion | GO:0010039 | 6 | 0.078 | |
| b cell activation | GO:0042113 | 33 | 0.077 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.077 | |
| organelle fission | GO:0048285 | 149 | 0.076 | |
| b cell homeostasis | GO:0001782 | 1 | 0.076 | Mouse |
| homeostasis of number of cells | GO:0048872 | 40 | 0.075 | Mouse |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.075 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.075 | |
| negative regulation of homeostatic process | GO:0032845 | 59 | 0.074 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:2001267 | 2 | 0.074 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.073 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.071 | |
| blood vessel remodeling | GO:0001974 | 2 | 0.071 | |
| renal system development | GO:0072001 | 63 | 0.070 | Mouse |
| cellular monovalent inorganic cation homeostasis | GO:0030004 | 26 | 0.070 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.070 | |
