| peptidyl serine autophosphorylation | GO:0036289 | 2 | 1.000 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.999 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.999 | |
| positive regulation of protein linear polyubiquitination | GO:1902530 | 2 | 0.999 | Human |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.999 | |
| cellular response to muramyl dipeptide | GO:0071225 | 3 | 0.998 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.997 | Human |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.996 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.995 | |
| positive regulation of canonical wnt signaling pathway | GO:0090263 | 33 | 0.994 | Human |
| regulation of protein linear polyubiquitination | GO:1902528 | 2 | 0.994 | Human |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.994 | |
| protein ubiquitination | GO:0016567 | 314 | 0.990 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.989 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.989 | |
| regulation of necroptotic process | GO:0060544 | 7 | 0.987 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.987 | |
| positive regulation of protein monoubiquitination | GO:1902527 | 1 | 0.986 | |
| positive regulation of protein k48 linked ubiquitination | GO:1902524 | 1 | 0.986 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.984 | |
| regulation of natural killer cell apoptotic process | GO:0070247 | 1 | 0.982 | Human |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.981 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.981 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.980 | |
| protein k48 linked ubiquitination | GO:0070936 | 38 | 0.979 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.979 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.978 | |
| protein processing | GO:0016485 | 226 | 0.978 | Human |
| toll like receptor 2 signaling pathway | GO:0034134 | 4 | 0.977 | |
| regulation of macrophage differentiation | GO:0045649 | 9 | 0.977 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.976 | |
| programmed necrotic cell death | GO:0097300 | 18 | 0.974 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.973 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.970 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.968 | |
| positive regulation of tumor necrosis factor superfamily cytokine production | GO:1903557 | 22 | 0.966 | |
| response to cytokine | GO:0034097 | 232 | 0.963 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.961 | |
| regulation of protein monoubiquitination | GO:1902525 | 1 | 0.955 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.955 | Human |
| positive regulation of macrophage differentiation | GO:0045651 | 7 | 0.955 | |
| positive regulation of protein k63 linked ubiquitination | GO:1902523 | 1 | 0.953 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.946 | |
| positive regulation of protein polyubiquitination | GO:1902916 | 3 | 0.944 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.939 | |
| innate immune response | GO:0045087 | 178 | 0.935 | |
| protein catabolic process | GO:0030163 | 325 | 0.933 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.932 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.928 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.924 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 26 | 0.924 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.914 | Human |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.908 | Human |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.907 | Human |
| positive regulation of defense response | GO:0031349 | 87 | 0.900 | |
| activation of innate immune response | GO:0002218 | 55 | 0.893 | |
| carbohydrate derivative transport | GO:1901264 | 20 | 0.890 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.888 | |
| protein maturation | GO:0051604 | 233 | 0.884 | Human |
| regulation of lymphocyte apoptotic process | GO:0070228 | 15 | 0.875 | Human |
| response to nitrogen compound | GO:1901698 | 184 | 0.870 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.868 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.867 | |
| positive regulation of necrotic cell death | GO:0010940 | 4 | 0.864 | |
| positive regulation of tumor necrosis factor production | GO:0032760 | 21 | 0.862 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.855 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.854 | |
| jnk cascade | GO:0007254 | 80 | 0.851 | |
| canonical wnt signaling pathway | GO:0060070 | 116 | 0.842 | Human |
| necroptotic process | GO:0070266 | 16 | 0.841 | |
| positive regulation of wnt signaling pathway | GO:0030177 | 54 | 0.834 | Human |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.830 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.828 | |
| protein linear polyubiquitination | GO:0097039 | 5 | 0.823 | Human |
| response to biotic stimulus | GO:0009607 | 276 | 0.810 | |
| regulation of necrotic cell death | GO:0010939 | 9 | 0.805 | |
| trail activated apoptotic signaling pathway | GO:0036462 | 4 | 0.796 | |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.794 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.785 | Human |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.774 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.763 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.741 | Human |
| activation of protein kinase activity | GO:0032147 | 90 | 0.729 | |
| regulation of nucleoside transport | GO:0032242 | 1 | 0.723 | |
| ripoptosome assembly | GO:0097343 | 1 | 0.723 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.716 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.713 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.713 | Human |
| protein autoubiquitination | GO:0051865 | 37 | 0.703 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.699 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.698 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.691 | |
| protein oligomerization | GO:0051259 | 173 | 0.686 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.686 | Human |
| leukocyte apoptotic process | GO:0071887 | 31 | 0.683 | Human |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.681 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.674 | Human |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.671 | |
| necroptotic signaling pathway | GO:0097527 | 6 | 0.670 | |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.669 | |
| nucleoside transport | GO:0015858 | 8 | 0.663 | |
| regulation of ion transmembrane transport | GO:0034765 | 132 | 0.662 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.660 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.657 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.653 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.647 | Human |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.647 | Human |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.637 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.637 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.608 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.608 | |
| protein k63 linked ubiquitination | GO:0070534 | 31 | 0.605 | |
| regulation of protein k63 linked ubiquitination | GO:1900044 | 6 | 0.604 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.589 | |
| regulation of t cell proliferation | GO:0042129 | 42 | 0.576 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.574 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.562 | |
| negative regulation of i kappab kinase nf kappab signaling | GO:0043124 | 32 | 0.556 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.555 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.552 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.550 | Human |
| necrotic cell death | GO:0070265 | 21 | 0.544 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.540 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.540 | Human |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.529 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 48 | 0.517 | |
| response to lipoteichoic acid | GO:0070391 | 3 | 0.514 | |
| regulation of anion transport | GO:0044070 | 25 | 0.509 | |
| peptidyl threonine modification | GO:0018210 | 45 | 0.499 | |
| immune system development | GO:0002520 | 195 | 0.496 | |
| amyloid fibril formation | GO:1990000 | 3 | 0.485 | |
| transmembrane transport | GO:0055085 | 399 | 0.472 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 37 | 0.472 | |
| zymogen activation | GO:0031638 | 70 | 0.470 | |
| immune effector process | GO:0002252 | 159 | 0.456 | |
| positive regulation of interleukin 8 production | GO:0032757 | 36 | 0.453 | |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.452 | |
| regulation of protein stability | GO:0031647 | 87 | 0.447 | |
| regulation of transporter activity | GO:0032409 | 82 | 0.442 | |
| regulation of immune response | GO:0050776 | 201 | 0.434 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.430 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.427 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 31 | 0.426 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.425 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.414 | |
| positive regulation of necroptotic process | GO:0060545 | 2 | 0.402 | |
| defense response | GO:0006952 | 315 | 0.399 | |
| activation of immune response | GO:0002253 | 114 | 0.394 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.391 | Human |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.389 | |
| hemopoiesis | GO:0030097 | 180 | 0.388 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.388 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.380 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.368 | Human |
| response to lipid | GO:0033993 | 206 | 0.368 | |
| amine metabolic process | GO:0009308 | 44 | 0.359 | |
| regulation of immune effector process | GO:0002697 | 91 | 0.357 | |
| dephosphorylation | GO:0016311 | 209 | 0.357 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.350 | Human |
| positive regulation of immune system process | GO:0002684 | 283 | 0.348 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.328 | Human |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.317 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.316 | |
| regulation of dephosphorylation | GO:0035303 | 96 | 0.312 | |
| adaptive immune response | GO:0002250 | 49 | 0.311 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.305 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.295 | Human |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.288 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 88 | 0.284 | Human |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.283 | |
| regulation of adaptive immune response | GO:0002819 | 33 | 0.281 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.281 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.281 | |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.269 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.264 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.252 | |
| mapk cascade | GO:0000165 | 288 | 0.247 | |
| cytokine production | GO:0001816 | 247 | 0.247 | |
| neural tube formation | GO:0001841 | 3 | 0.246 | |
| positive regulation of stress activated protein kinase signaling cascade | GO:0070304 | 61 | 0.245 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.240 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.238 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.237 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.229 | |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.225 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 61 | 0.224 | |
| response to growth factor | GO:0070848 | 205 | 0.221 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.220 | Human |
| lymphocyte homeostasis | GO:0002260 | 4 | 0.218 | |
| regulation of map kinase activity | GO:0043405 | 108 | 0.216 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.215 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.215 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.208 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.208 | Human |
| regulation of cytokine production | GO:0001817 | 232 | 0.207 | |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.207 | |
| response to peptidoglycan | GO:0032494 | 3 | 0.201 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 22 | 0.201 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.195 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.194 | |
| regulation of peptidyl serine phosphorylation | GO:0033135 | 50 | 0.194 | |
| gtp metabolic process | GO:0046039 | 239 | 0.184 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.183 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 22 | 0.180 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.175 | |
| negative regulation of g1 s transition of mitotic cell cycle | GO:2000134 | 29 | 0.174 | |
| t cell proliferation | GO:0042098 | 45 | 0.167 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.166 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.159 | |
| response to radiation | GO:0009314 | 151 | 0.157 | |
| response to hypoxia | GO:0001666 | 96 | 0.156 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.156 | |
| defense response to bacterium | GO:0042742 | 63 | 0.155 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.154 | |
| protein modification by small protein removal | GO:0070646 | 92 | 0.154 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.153 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.153 | |
| fibril organization | GO:0097435 | 10 | 0.151 | |
| rna processing | GO:0006396 | 255 | 0.149 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.148 | |
| regulation of leukocyte apoptotic process | GO:2000106 | 25 | 0.146 | Human |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.146 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.145 | |
| regulation of defense response | GO:0031347 | 154 | 0.142 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.142 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.141 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.138 | |
| protein secretion | GO:0009306 | 98 | 0.137 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.136 | |
| spermatid development | GO:0007286 | 4 | 0.132 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.130 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.127 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.125 | |
| macrophage differentiation | GO:0030225 | 11 | 0.124 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.123 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.120 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.119 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.118 | |
| negative regulation of protein ubiquitination | GO:0031397 | 35 | 0.117 | |
| regulation of t cell activation | GO:0050863 | 77 | 0.116 | |
| positive regulation of dna binding | GO:0043388 | 17 | 0.116 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.115 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.114 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.112 | |
| release of cytochrome c from mitochondria | GO:0001836 | 35 | 0.108 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.108 | |
| mitochondrion organization | GO:0007005 | 156 | 0.107 | |
| regulation of interleukin 8 production | GO:0032677 | 49 | 0.107 | |
| limbic system development | GO:0021761 | 3 | 0.107 | |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.107 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.105 | |
| response to cobalt ion | GO:0032025 | 1 | 0.105 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.105 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.105 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.105 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.102 | |
| response to virus | GO:0009615 | 126 | 0.100 | |
| regulation of atp adp antiporter activity | GO:0070926 | 1 | 0.096 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.093 | |
| positive regulation of t cell cytokine production | GO:0002726 | 4 | 0.093 | |
| positive regulation of innate immune response | GO:0045089 | 79 | 0.091 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.090 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.090 | |
| mrna metabolic process | GO:0016071 | 175 | 0.089 | |
| interleukin 2 production | GO:0032623 | 20 | 0.089 | |
| positive regulation of cell cycle arrest | GO:0071158 | 23 | 0.088 | |
| interleukin 6 production | GO:0032635 | 37 | 0.088 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.087 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 108 | 0.087 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.086 | |
| response to uv | GO:0009411 | 73 | 0.086 | |
| protein deubiquitination | GO:0016579 | 79 | 0.081 | |
| execution phase of apoptosis | GO:0097194 | 32 | 0.081 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 19 | 0.080 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.080 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.080 | |
| regulation of protein localization | GO:0032880 | 296 | 0.079 | |
| regulation of protein transport | GO:0051223 | 213 | 0.079 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.079 | |
| regulation of cell cycle arrest | GO:0071156 | 36 | 0.078 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.078 | |
| post embryonic development | GO:0009791 | 2 | 0.078 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.076 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.076 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.076 | |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.075 | |
| epithelium development | GO:0060429 | 227 | 0.075 | |
| lymphocyte activation | GO:0046649 | 133 | 0.074 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.072 | |
| signal transduction involved in dna damage checkpoint | GO:0072422 | 15 | 0.072 | |
| t cell receptor signaling pathway | GO:0050852 | 21 | 0.071 | |
| lymphocyte apoptotic process | GO:0070227 | 20 | 0.070 | Human |
| leukocyte activation | GO:0045321 | 164 | 0.069 | |
| central nervous system development | GO:0007417 | 123 | 0.069 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.069 | |
| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 4 | 0.069 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.068 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.068 | |
| immature t cell proliferation | GO:0033079 | 1 | 0.068 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.067 | |
| secretion | GO:0046903 | 254 | 0.067 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.064 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.063 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.063 | |
| response to peptide | GO:1901652 | 65 | 0.063 | |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.063 | |
| positive regulation of t helper 1 type immune response | GO:0002827 | 4 | 0.062 | |
| immune response | GO:0006955 | 307 | 0.062 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.061 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.061 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.061 | |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 4 | 0.059 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.059 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.058 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.057 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.057 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.056 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.056 | |
| activated t cell proliferation | GO:0050798 | 13 | 0.056 | |
| regulation of protein processing | GO:0070613 | 150 | 0.055 | Human |
| positive regulation of peptidyl threonine phosphorylation | GO:0010800 | 9 | 0.055 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.054 | |
| regulation of interleukin 6 production | GO:0032675 | 37 | 0.053 | |
| neurological system process | GO:0050877 | 163 | 0.053 | |
| anterior posterior axis specification embryo | GO:0008595 | 2 | 0.053 | |
| signal transduction involved in mitotic cell cycle checkpoint | GO:0072413 | 13 | 0.053 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 40 | 0.053 | |
| anion transport | GO:0006820 | 161 | 0.052 | |
| dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest | GO:0006977 | 9 | 0.051 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.051 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.051 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.051 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.050 | |
| mitotic g1 dna damage checkpoint | GO:0031571 | 17 | 0.050 | |
| neuron death | GO:0070997 | 65 | 0.049 | |
| positive regulation of phosphatase activity | GO:0010922 | 14 | 0.049 | |
| mitotic dna integrity checkpoint | GO:0044774 | 30 | 0.049 | |
| primary neural tube formation | GO:0014020 | 3 | 0.049 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.048 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.048 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.047 | |
| spliceosomal snrnp assembly | GO:0000387 | 28 | 0.047 | |
| cellular response to radiation | GO:0071478 | 65 | 0.046 | |
| innate immune response activating signal transduction | GO:0002758 | 48 | 0.046 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.046 | |
| spermatid differentiation | GO:0048515 | 4 | 0.046 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 8 | 0.046 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.045 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.045 | |
| cellular response to uv | GO:0034644 | 32 | 0.045 | |
| regulation of protein polyubiquitination | GO:1902914 | 8 | 0.044 | |
| negative regulation of protein polyubiquitination | GO:1902915 | 4 | 0.044 | |
| negative regulation of necroptotic process | GO:0060546 | 2 | 0.044 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.044 | |
| positive regulation of adaptive immune response | GO:0002821 | 21 | 0.044 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.043 | |
| response to bacterium | GO:0009617 | 144 | 0.043 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.042 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.042 | |
| nucleotide binding domain leucine rich repeat containing receptor signaling pathway | GO:0035872 | 5 | 0.042 | |
| protein heterooligomerization | GO:0051291 | 16 | 0.041 | |
| cellular response to lipid | GO:0071396 | 127 | 0.041 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.040 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.040 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.040 | |
| embryo development | GO:0009790 | 123 | 0.040 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.039 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.039 | |
| positive regulation of dephosphorylation | GO:0035306 | 26 | 0.039 | |
| histone ubiquitination | GO:0016574 | 31 | 0.039 | |
| male gamete generation | GO:0048232 | 22 | 0.038 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.038 | |
| signal transduction involved in dna integrity checkpoint | GO:0072401 | 15 | 0.038 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.038 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.038 | |
| protein homooligomerization | GO:0051260 | 100 | 0.038 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.038 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 42 | 0.037 | |
| defense response to gram positive bacterium | GO:0050830 | 29 | 0.037 | |
| regulation of neuron apoptotic process | GO:0043523 | 35 | 0.037 | |
| cellular response to glucocorticoid stimulus | GO:0071385 | 4 | 0.037 | |
| substantia nigra development | GO:0021762 | 45 | 0.037 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.037 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.037 | |
| interleukin 2 secretion | GO:0070970 | 3 | 0.036 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.036 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.036 | |
| hippocampus development | GO:0021766 | 1 | 0.036 | |
| lipid metabolic process | GO:0006629 | 381 | 0.036 | |
| organelle fission | GO:0048285 | 149 | 0.036 | |
| positive regulation of interleukin 6 production | GO:0032755 | 21 | 0.036 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.035 | |
| interleukin 8 production | GO:0032637 | 51 | 0.035 | |
| neuron apoptotic process | GO:0051402 | 39 | 0.035 | |
| mrna splicing via spliceosome | GO:0000398 | 89 | 0.035 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.034 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.034 | |
| interferon gamma production | GO:0032609 | 39 | 0.034 | |
| intracellular protein transport | GO:0006886 | 270 | 0.034 | |
| circulatory system development | GO:0072359 | 262 | 0.034 | |
| mitotic g1 s transition checkpoint | GO:0044819 | 17 | 0.034 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.034 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.033 | |
| positive regulation of interleukin 2 production | GO:0032743 | 11 | 0.033 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.033 | |
| myoblast fusion | GO:0007520 | 1 | 0.032 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.032 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.032 | |
| cerebellum development | GO:0021549 | 2 | 0.032 | |
| positive regulation of protein binding | GO:0032092 | 24 | 0.031 | |
| organelle assembly | GO:0070925 | 176 | 0.031 | |
| entry into other organism involved in symbiotic interaction | GO:0051828 | 25 | 0.031 | |
| response to oxidative stress | GO:0006979 | 121 | 0.031 | |
| positive regulation of protein homodimerization activity | GO:0090073 | 5 | 0.031 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.031 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.030 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.030 | |
| signal transduction in absence of ligand | GO:0038034 | 22 | 0.030 | |
| negative regulation of phosphatase activity | GO:0010923 | 61 | 0.030 | |
| rna splicing | GO:0008380 | 131 | 0.029 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.029 | |
| g1 dna damage checkpoint | GO:0044783 | 18 | 0.029 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 26 | 0.029 | |
| protein stabilization | GO:0050821 | 64 | 0.029 | |
| cell projection organization | GO:0030030 | 252 | 0.028 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 89 | 0.028 | |
| inner ear morphogenesis | GO:0042472 | 4 | 0.028 | |
| chordate embryonic development | GO:0043009 | 34 | 0.028 | |
| intracellular mrna localization | GO:0008298 | 1 | 0.028 | |
| regulation of t helper 1 type immune response | GO:0002825 | 5 | 0.028 | |
| intracellular signal transduction involved in g1 dna damage checkpoint | GO:1902400 | 10 | 0.028 | |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.028 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.027 | |
| protein k48 linked deubiquitination | GO:0071108 | 19 | 0.027 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.027 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.027 | |
| positive regulation of interleukin 1 beta secretion | GO:0050718 | 11 | 0.027 | |
| regulation of t cell mediated immunity | GO:0002709 | 18 | 0.027 | |
| protein localization to organelle | GO:0033365 | 280 | 0.027 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.026 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.026 | |
| positive regulation of transport | GO:0051050 | 336 | 0.026 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.026 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.026 | |
| negative regulation of dna metabolic process | GO:0051053 | 57 | 0.026 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.026 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.026 | |
| regulation of t helper 1 cell differentiation | GO:0045625 | 1 | 0.026 | |
| mrna processing | GO:0006397 | 133 | 0.026 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.026 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.025 | |
| head development | GO:0060322 | 108 | 0.025 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.025 | |
| single organism reproductive process | GO:0044702 | 98 | 0.025 | |
| response to oxygen levels | GO:0070482 | 100 | 0.024 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.024 | |
| regulation of tumor necrosis factor production | GO:0032680 | 43 | 0.024 | |
| forebrain neuron development | GO:0021884 | 2 | 0.024 | |
| regulation of jnk cascade | GO:0046328 | 73 | 0.024 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.024 | |
| fibroblast proliferation | GO:0048144 | 33 | 0.024 | |
| negative regulation of protein k63 linked ubiquitination | GO:1900045 | 4 | 0.023 | |
| actin filament based process | GO:0030029 | 224 | 0.023 | |
| response to light stimulus | GO:0009416 | 87 | 0.023 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.023 | |
| protein targeting | GO:0006605 | 187 | 0.023 | |
| cellular response to toxic substance | GO:0097237 | 4 | 0.023 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.023 | |
| heart development | GO:0007507 | 95 | 0.022 | |
| coenzyme metabolic process | GO:0006732 | 65 | 0.022 | |
| bmp signaling pathway | GO:0030509 | 49 | 0.022 | |
| release of cytoplasmic sequestered nf kappab | GO:0008588 | 4 | 0.022 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 21 | 0.022 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.022 | |
| skin development | GO:0043588 | 76 | 0.021 | |
| regulation of actin filament polymerization | GO:0030833 | 50 | 0.021 | |
| t cell cytokine production | GO:0002369 | 12 | 0.021 | |
| reproductive process | GO:0022414 | 106 | 0.021 | |
| microtubule based process | GO:0007017 | 210 | 0.021 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.021 | |
| entry into host | GO:0044409 | 25 | 0.021 | |
| tissue regeneration | GO:0042246 | 3 | 0.021 | |
| segmentation | GO:0035282 | 4 | 0.021 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.020 | |
| neurogenesis | GO:0022008 | 169 | 0.020 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.020 | |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.020 | |
| aging | GO:0007568 | 66 | 0.020 | |
| positive regulation of peptidyl serine phosphorylation | GO:0033138 | 42 | 0.020 | |
| epithelial tube morphogenesis | GO:0060562 | 38 | 0.020 | |
