| spindle assembly checkpoint | GO:0071173 | 17 | 0.773 | |
| negative regulation of mitotic sister chromatid segregation | GO:0033048 | 17 | 0.674 | |
| chromosome segregation | GO:0007059 | 114 | 0.657 | |
| negative regulation of phosphatase activity | GO:0010923 | 61 | 0.546 | |
| sister chromatid cohesion | GO:0007062 | 24 | 0.512 | |
| attachment of spindle microtubules to kinetochore | GO:0008608 | 17 | 0.355 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.348 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.346 | |
| protein localization to chromosome centromeric region | GO:0071459 | 12 | 0.314 | |
| dephosphorylation | GO:0016311 | 209 | 0.313 | |
| regulation of dephosphorylation | GO:0035303 | 96 | 0.304 | |
| mitotic spindle assembly checkpoint | GO:0007094 | 14 | 0.278 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.260 | |
| regulation of mitotic sister chromatid segregation | GO:0033047 | 27 | 0.243 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.234 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.228 | |
| centromeric sister chromatid cohesion | GO:0070601 | 3 | 0.224 | |
| regulation of protein processing | GO:0070613 | 150 | 0.224 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.207 | |
| negative regulation of chromosome segregation | GO:0051985 | 18 | 0.187 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.174 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.172 | |
| post embryonic development | GO:0009791 | 2 | 0.158 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.156 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.154 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.153 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.147 | |
| protein localization to organelle | GO:0033365 | 280 | 0.144 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.143 | |
| protein localization to kinetochore | GO:0034501 | 10 | 0.142 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.140 | |
| circulatory system development | GO:0072359 | 262 | 0.138 | |
| chromosome separation | GO:0051304 | 23 | 0.134 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.129 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.127 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.119 | |
| organelle assembly | GO:0070925 | 176 | 0.117 | |
| negative regulation of sister chromatid segregation | GO:0033046 | 17 | 0.116 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.112 | |
| maintenance of protein location | GO:0045185 | 57 | 0.111 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.108 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.106 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.102 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.101 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.100 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.100 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.099 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.099 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.098 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.098 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.095 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.094 | |
| regulation of sister chromatid cohesion | GO:0007063 | 9 | 0.092 | |
| negative regulation of mitotic metaphase anaphase transition | GO:0045841 | 17 | 0.091 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.091 | |
| protein maturation | GO:0051604 | 233 | 0.090 | |
| protein processing | GO:0016485 | 226 | 0.086 | |
| protein catabolic process | GO:0030163 | 325 | 0.086 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.085 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.080 | |
| organelle fission | GO:0048285 | 149 | 0.080 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.079 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.079 | |
| anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031145 | 25 | 0.078 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.069 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.068 | |
| mitotic spindle checkpoint | GO:0071174 | 18 | 0.066 | |
| protein dephosphorylation | GO:0006470 | 81 | 0.065 | |
| regulation of mitosis | GO:0007088 | 63 | 0.065 | |
| single organism membrane organization | GO:0044802 | 268 | 0.065 | |
| regulation of cell division | GO:0051302 | 116 | 0.063 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.062 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.062 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.062 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 32 | 0.061 | |
| multi organism cellular process | GO:0044764 | 156 | 0.060 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.060 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.059 | |
| negative regulation of mitotic sister chromatid separation | GO:2000816 | 17 | 0.059 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.058 | |
| microtubule anchoring | GO:0034453 | 24 | 0.056 | |
| metaphase anaphase transition of cell cycle | GO:0044784 | 21 | 0.053 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.053 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.053 | |
| amine metabolic process | GO:0009308 | 44 | 0.052 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.052 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.051 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.051 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.051 | |
| regulation of sister chromatid segregation | GO:0033045 | 27 | 0.049 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.049 | |
| histone modification | GO:0016570 | 251 | 0.049 | |
| metaphase anaphase transition of mitotic cell cycle | GO:0007091 | 21 | 0.048 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.046 | |
| regulation of mitotic sister chromatid separation | GO:0010965 | 27 | 0.046 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.046 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.046 | |
| mitotic sister chromatid separation | GO:0051306 | 18 | 0.046 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.043 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.043 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.042 | |
| regulation of nuclear division | GO:0051783 | 65 | 0.042 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.040 | |
| negative regulation of dephosphorylation | GO:0035305 | 63 | 0.039 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.039 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.039 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.039 | |
| cell projection organization | GO:0030030 | 252 | 0.038 | |
| male meiosis | GO:0007140 | 1 | 0.038 | |
| regulation of protein dephosphorylation | GO:0035304 | 18 | 0.037 | |
| protein dna complex subunit organization | GO:0071824 | 80 | 0.037 | |
| oogenesis | GO:0048477 | 2 | 0.037 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.037 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.036 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.035 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.035 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.035 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.034 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.034 | |
| chemical homeostasis | GO:0048878 | 306 | 0.033 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.033 | |
| regulation of metaphase anaphase transition of cell cycle | GO:1902099 | 26 | 0.033 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.033 | |
| membrane organization | GO:0061024 | 292 | 0.033 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.032 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.031 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.031 | |
| single organism cellular localization | GO:1902580 | 332 | 0.031 | |
| attachment of mitotic spindle microtubules to kinetochore | GO:0051315 | 3 | 0.030 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.030 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.030 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.029 | |
| positive regulation of chromosome segregation | GO:0051984 | 9 | 0.029 | |
| negative regulation of cell division | GO:0051782 | 31 | 0.029 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.028 | |
| maintenance of location | GO:0051235 | 112 | 0.027 | |
| cardiovascular system development | GO:0072358 | 262 | 0.027 | |
| regulation of protein localization | GO:0032880 | 296 | 0.027 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 28 | 0.026 | |
| female gamete generation | GO:0007292 | 2 | 0.026 | |
| heart development | GO:0007507 | 95 | 0.026 | |
| protein acetylation | GO:0006473 | 116 | 0.026 | |
| limbic system development | GO:0021761 | 3 | 0.025 | |
| metaphase plate congression | GO:0051310 | 18 | 0.025 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.025 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.025 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.025 | |
| microtubule based process | GO:0007017 | 210 | 0.025 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.024 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.024 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.024 | |
| intracellular protein transport | GO:0006886 | 270 | 0.024 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.024 | |
| metal ion transport | GO:0030001 | 272 | 0.023 | |
| negative regulation of metaphase anaphase transition of cell cycle | GO:1902100 | 17 | 0.023 | |
| negative regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032435 | 30 | 0.023 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.023 | |
| system process | GO:0003008 | 349 | 0.023 | |
| cell growth | GO:0016049 | 160 | 0.022 | |
| actin filament based movement | GO:0030048 | 17 | 0.022 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.022 | |
| tissue regeneration | GO:0042246 | 3 | 0.022 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.021 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 83 | 0.021 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.021 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.020 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.020 | |
| photoreceptor cell differentiation | GO:0046530 | 2 | 0.020 | |
| viral life cycle | GO:0019058 | 132 | 0.020 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.019 | |
| organelle localization | GO:0051640 | 84 | 0.019 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.019 | |
| plasma membrane organization | GO:0007009 | 115 | 0.019 | |
| positive regulation of meiotic cell cycle | GO:0051446 | 2 | 0.019 | |
| regulation of cell motility | GO:2000145 | 299 | 0.018 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.018 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.018 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.018 | |
| regulation of locomotion | GO:0040012 | 329 | 0.018 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.018 | |
| secretion | GO:0046903 | 254 | 0.018 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.018 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 109 | 0.018 | |
| regulation of cell migration | GO:0030334 | 289 | 0.018 | |
| regulation of viral process | GO:0050792 | 103 | 0.017 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.017 | |
| actin filament based process | GO:0030029 | 224 | 0.017 | |
| actin mediated cell contraction | GO:0070252 | 12 | 0.017 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.017 | |
| cation transport | GO:0006812 | 331 | 0.017 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.017 | |
| response to radiation | GO:0009314 | 151 | 0.017 | |
| defense response | GO:0006952 | 315 | 0.017 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.016 | |
| viral process | GO:0016032 | 146 | 0.016 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.016 | |
| blastocyst development | GO:0001824 | 3 | 0.016 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.016 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.016 | |
| calcium ion transport | GO:0006816 | 147 | 0.016 | |
| cell projection assembly | GO:0030031 | 126 | 0.016 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.016 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.015 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.015 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.015 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.015 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.014 | |
| reproductive structure development | GO:0048608 | 55 | 0.014 | |
| endosomal transport | GO:0016197 | 129 | 0.014 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.014 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.014 | |
| reproductive system development | GO:0061458 | 56 | 0.014 | |
| neurological system process | GO:0050877 | 163 | 0.014 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.014 | |
| locomotory behavior | GO:0007626 | 1 | 0.014 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.013 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.013 | |
| neuron development | GO:0048666 | 113 | 0.013 | |
| spindle checkpoint | GO:0031577 | 26 | 0.013 | |
| growth | GO:0040007 | 202 | 0.013 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.013 | |
| cellular response to ammonium ion | GO:0071242 | 4 | 0.013 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.013 | |
| regulation of cell projection organization | GO:0031344 | 107 | 0.013 | |
| protein acylation | GO:0043543 | 138 | 0.013 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.013 | |
| positive regulation of transport | GO:0051050 | 336 | 0.012 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.012 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.012 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.012 | |
| cell morphogenesis | GO:0000902 | 296 | 0.012 | |
| hindbrain development | GO:0030902 | 3 | 0.012 | |
| epithelium development | GO:0060429 | 227 | 0.012 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.012 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.012 | |
| peptidyl threonine modification | GO:0018210 | 45 | 0.012 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.012 | |
| oocyte development | GO:0048599 | 1 | 0.012 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.012 | |
| chromatin modification | GO:0016568 | 298 | 0.012 | |
| immune system development | GO:0002520 | 195 | 0.012 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.012 | |
| neurogenesis | GO:0022008 | 169 | 0.012 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.012 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.012 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.011 | |
| embryonic placenta development | GO:0001892 | 1 | 0.011 | |
| cell substrate adhesion | GO:0031589 | 132 | 0.011 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.011 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.011 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.011 | |
| rna processing | GO:0006396 | 255 | 0.011 | |
| cation homeostasis | GO:0055080 | 189 | 0.011 | |
| protein targeting | GO:0006605 | 187 | 0.011 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.011 | |
| ossification | GO:0001503 | 121 | 0.010 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.010 | |
| regulation of dna replication | GO:0006275 | 68 | 0.010 | |
| regeneration | GO:0031099 | 4 | 0.010 | |
| regulation of protein transport | GO:0051223 | 213 | 0.010 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.010 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.010 | |
| negative regulation of mitosis | GO:0045839 | 24 | 0.010 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.010 | |
| dna replication | GO:0006260 | 116 | 0.010 | |
