| recombinational repair | GO:0000725 | 50 | 0.951 | Yeast |
| dna replication initiation | GO:0006270 | 6 | 0.940 | Yeast |
| dna dependent dna replication | GO:0006261 | 44 | 0.868 | |
| protein dna complex assembly | GO:0065004 | 64 | 0.841 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.786 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.765 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.704 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.570 | |
| atp catabolic process | GO:0006200 | 157 | 0.566 | |
| dna packaging | GO:0006323 | 77 | 0.540 | |
| dna replication | GO:0006260 | 116 | 0.500 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.475 | Yeast |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.460 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.415 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.392 | |
| post embryonic development | GO:0009791 | 2 | 0.365 | Fly |
| chromosome segregation | GO:0007059 | 114 | 0.362 | |
| dna recombination | GO:0006310 | 77 | 0.320 | Yeast |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.314 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.304 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.302 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.296 | |
| dna duplex unwinding | GO:0032508 | 30 | 0.264 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.260 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.253 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.249 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.248 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.234 | |
| female gamete generation | GO:0007292 | 2 | 0.232 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.231 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.207 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.204 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.194 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.194 | |
| dna repair | GO:0006281 | 198 | 0.194 | Yeast |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.187 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.185 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.173 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.173 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.165 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.164 | |
| dna conformation change | GO:0071103 | 113 | 0.163 | |
| organelle fission | GO:0048285 | 149 | 0.160 | Yeast |
| determination of adult lifespan | GO:0008340 | 2 | 0.157 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.154 | |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.154 | Yeast |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.154 | |
| embryo development | GO:0009790 | 123 | 0.151 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.147 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.146 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.141 | Yeast |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.140 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.129 | |
| dna biosynthetic process | GO:0071897 | 40 | 0.129 | |
| cell development | GO:0048468 | 328 | 0.128 | Fly |
| cellular protein complex assembly | GO:0043623 | 188 | 0.126 | |
| spindle organization | GO:0007051 | 53 | 0.124 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.119 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.117 | |
| double strand break repair | GO:0006302 | 101 | 0.114 | Yeast |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.114 | Yeast |
| dna geometric change | GO:0032392 | 32 | 0.113 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.113 | |
| reproductive process | GO:0022414 | 106 | 0.109 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.107 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.106 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.106 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.106 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.105 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 73 | 0.105 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.102 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.101 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.101 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.101 | |
| double strand break repair via homologous recombination | GO:0000724 | 50 | 0.100 | Yeast |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.100 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.099 | |
| growth | GO:0040007 | 202 | 0.099 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.099 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.099 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.097 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.095 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.093 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.090 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.088 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.086 | |
| nervous system development | GO:0007399 | 293 | 0.085 | |
| microtubule based process | GO:0007017 | 210 | 0.085 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.085 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.084 | Yeast |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.084 | |
| regulation of sister chromatid segregation | GO:0033045 | 27 | 0.083 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.079 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.078 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.075 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.074 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.073 | |
| positive regulation of cytokinesis | GO:0032467 | 29 | 0.072 | |
| atp metabolic process | GO:0046034 | 176 | 0.071 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.071 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.071 | |
| mitotic dna integrity checkpoint | GO:0044774 | 30 | 0.071 | |
| nuclear division | GO:0000280 | 128 | 0.070 | Yeast |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.069 | |
| meiotic chromosome separation | GO:0051307 | 3 | 0.068 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.067 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.067 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.066 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.062 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.062 | |
| cell projection organization | GO:0030030 | 252 | 0.062 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.062 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.061 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 40 | 0.060 | |
| g2 dna damage checkpoint | GO:0031572 | 26 | 0.060 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.059 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.059 | |
| regulation of cell division | GO:0051302 | 116 | 0.057 | Yeast |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.056 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.056 | |
| response to cytokine | GO:0034097 | 232 | 0.053 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.053 | |
| chromosome separation | GO:0051304 | 23 | 0.052 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.051 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.051 | |
| actin filament based process | GO:0030029 | 224 | 0.050 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.050 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.049 | |
| neurogenesis | GO:0022008 | 169 | 0.049 | |
| regulation of nuclear division | GO:0051783 | 65 | 0.049 | Yeast |
| cellular component morphogenesis | GO:0032989 | 314 | 0.048 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 41 | 0.048 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.046 | Yeast |
| chromatin organization | GO:0006325 | 351 | 0.045 | |
| cell cycle dna replication | GO:0044786 | 11 | 0.044 | |
| protein dna complex subunit organization | GO:0071824 | 80 | 0.044 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.044 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.043 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 19 | 0.043 | Yeast |
| protein catabolic process | GO:0030163 | 325 | 0.042 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.042 | Yeast |
| myosin filament assembly | GO:0031034 | 2 | 0.042 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.040 | Yeast |
| protein alkylation | GO:0008213 | 74 | 0.040 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.039 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.039 | |
| regulation of chromatin silencing | GO:0031935 | 8 | 0.038 | Yeast |
| gtp metabolic process | GO:0046039 | 239 | 0.037 | |
| protein complex disassembly | GO:0043241 | 52 | 0.036 | |
| metaphase anaphase transition of cell cycle | GO:0044784 | 21 | 0.035 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.035 | |
| dna strand elongation involved in dna replication | GO:0006271 | 3 | 0.035 | |
| organelle assembly | GO:0070925 | 176 | 0.035 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.034 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.034 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.033 | |
| response to radiation | GO:0009314 | 151 | 0.033 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.033 | |
| heterochromatin organization | GO:0070828 | 6 | 0.032 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.031 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.031 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.031 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 2 | 0.031 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.031 | Yeast |
| regulation of cytokinesis | GO:0032465 | 45 | 0.031 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.030 | Yeast |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.029 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.029 | |
| sister chromatid segregation | GO:0000819 | 54 | 0.029 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.029 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.028 | |
| regulation of mitotic sister chromatid separation | GO:0010965 | 27 | 0.028 | |
| protein localization to organelle | GO:0033365 | 280 | 0.028 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.028 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.028 | |
| negative regulation of dna metabolic process | GO:0051053 | 57 | 0.028 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.027 | |
| neuron development | GO:0048666 | 113 | 0.027 | |
| macromolecular complex disassembly | GO:0032984 | 60 | 0.027 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.027 | |
| blastocyst development | GO:0001824 | 3 | 0.027 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.027 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.027 | Yeast |
| cell morphogenesis | GO:0000902 | 296 | 0.026 | |
| regulation of g2 m transition of mitotic cell cycle | GO:0010389 | 20 | 0.025 | |
| generation of neurons | GO:0048699 | 152 | 0.025 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.025 | |
| rna splicing via transesterification reactions | GO:0000375 | 90 | 0.024 | |
| canonical wnt signaling pathway | GO:0060070 | 116 | 0.024 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.024 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.024 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.024 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.023 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.023 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.021 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.021 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.021 | |
| behavior | GO:0007610 | 112 | 0.021 | |
| neuron projection development | GO:0031175 | 106 | 0.021 | |
| nuclear dna replication | GO:0033260 | 6 | 0.021 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.021 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.021 | |
| response to inorganic substance | GO:0010035 | 127 | 0.019 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.019 | |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.019 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.019 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.019 | |
| oogenesis | GO:0048477 | 2 | 0.019 | |
| protein processing | GO:0016485 | 226 | 0.019 | |
| single organism reproductive process | GO:0044702 | 98 | 0.019 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.019 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.019 | |
| cell activation | GO:0001775 | 213 | 0.018 | |
| cell aging | GO:0007569 | 52 | 0.018 | |
| anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process | GO:0031145 | 25 | 0.018 | |
| gtp catabolic process | GO:0006184 | 237 | 0.018 | |
| reproduction | GO:0000003 | 63 | 0.018 | Yeast |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.018 | |
| regulation of atp catabolic process | GO:1903289 | 25 | 0.018 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.018 | |
| cell division | GO:0051301 | 168 | 0.017 | Yeast |
| regeneration | GO:0031099 | 4 | 0.017 | |
| cellular component disassembly | GO:0022411 | 92 | 0.017 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.017 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.017 | |
| telomere maintenance | GO:0000723 | 32 | 0.017 | |
| attachment of mitotic spindle microtubules to kinetochore | GO:0051315 | 3 | 0.016 | |
| tube morphogenesis | GO:0035239 | 95 | 0.016 | |
| metaphase anaphase transition of mitotic cell cycle | GO:0007091 | 21 | 0.016 | |
| actomyosin structure organization | GO:0031032 | 59 | 0.016 | |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.016 | |
| cell cycle arrest | GO:0007050 | 71 | 0.015 | |
| positive regulation of chromosome segregation | GO:0051984 | 9 | 0.015 | |
| myosin filament organization | GO:0031033 | 2 | 0.015 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.015 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.015 | |
| multi organism reproductive process | GO:0044703 | 54 | 0.014 | |
| biological adhesion | GO:0022610 | 331 | 0.014 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.014 | |
| attachment of spindle microtubules to kinetochore | GO:0008608 | 17 | 0.014 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.014 | |
| negative regulation of mitotic anaphase promoting complex activity | GO:0060564 | 4 | 0.014 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.014 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.014 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.013 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.013 | |
| reproductive system development | GO:0061458 | 56 | 0.013 | |
| protein ubiquitination | GO:0016567 | 314 | 0.013 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.013 | |
| meiosis i | GO:0007127 | 4 | 0.013 | Yeast |
| regulation of protein maturation | GO:1903317 | 150 | 0.013 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.013 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.013 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 35 | 0.013 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.013 | |
| response to metal ion | GO:0010038 | 84 | 0.012 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.012 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.012 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 56 | 0.012 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.012 | |
| neuron projection morphogenesis | GO:0048812 | 50 | 0.012 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.012 | |
| vasculature development | GO:0001944 | 181 | 0.012 | |
| neuron differentiation | GO:0030182 | 138 | 0.012 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.012 | |
| response to drug | GO:0042493 | 81 | 0.012 | |
| regulation of chromatin organization | GO:1902275 | 56 | 0.012 | |
| cell adhesion | GO:0007155 | 325 | 0.011 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 61 | 0.011 | |
| amine metabolic process | GO:0009308 | 44 | 0.011 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.011 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.011 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.011 | |
| ribosome assembly | GO:0042255 | 9 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.011 | |
| lymphocyte activation | GO:0046649 | 133 | 0.011 | |
| hemopoiesis | GO:0030097 | 180 | 0.010 | |
| sexual reproduction | GO:0019953 | 37 | 0.010 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.010 | |
| protein maturation | GO:0051604 | 233 | 0.010 | |
| negative regulation of chromosome organization | GO:2001251 | 48 | 0.010 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.010 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.010 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.010 | |
| response to light stimulus | GO:0009416 | 87 | 0.010 | |
| aging | GO:0007568 | 66 | 0.010 | |
| negative regulation of cell growth | GO:0030308 | 83 | 0.010 | |
| response to oxygen levels | GO:0070482 | 100 | 0.010 | |
