| cellular response to dna damage stimulus | GO:0006974 | 379 | 1.000 | |
| double strand break repair | GO:0006302 | 101 | 0.993 | |
| dna repair | GO:0006281 | 198 | 0.992 | |
| dna damage induced protein phosphorylation | GO:0006975 | 5 | 0.968 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.964 | |
| histone h3 acetylation | GO:0043966 | 45 | 0.963 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.960 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.958 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.955 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.918 | |
| male meiosis | GO:0007140 | 1 | 0.917 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 89 | 0.901 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.898 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.895 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.892 | |
| developmental programmed cell death | GO:0010623 | 3 | 0.887 | Fly |
| g1 s transition of mitotic cell cycle | GO:0000082 | 78 | 0.886 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.844 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 44 | 0.838 | |
| chromatin organization | GO:0006325 | 351 | 0.831 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.829 | Fly |
| double strand break repair via homologous recombination | GO:0000724 | 50 | 0.821 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.807 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.804 | |
| response to radiation | GO:0009314 | 151 | 0.796 | Mouse Fly |
| signal transduction in response to dna damage | GO:0042770 | 57 | 0.752 | |
| nuclear division | GO:0000280 | 128 | 0.750 | |
| mitotic dna damage checkpoint | GO:0044773 | 28 | 0.748 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.744 | |
| histone threonine phosphorylation | GO:0035405 | 7 | 0.735 | |
| spindle assembly | GO:0051225 | 29 | 0.730 | |
| chromatin modification | GO:0016568 | 298 | 0.714 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.713 | |
| chromosome segregation | GO:0007059 | 114 | 0.703 | Worm |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.700 | |
| post embryonic development | GO:0009791 | 2 | 0.692 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 40 | 0.684 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.676 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.674 | Fly |
| negative regulation of cell cycle process | GO:0010948 | 121 | 0.666 | |
| mitotic dna integrity checkpoint | GO:0044774 | 30 | 0.663 | |
| internal peptidyl lysine acetylation | GO:0018393 | 97 | 0.660 | |
| dna geometric change | GO:0032392 | 32 | 0.637 | |
| double strand break repair via single strand annealing | GO:0045002 | 4 | 0.609 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.597 | Fly |
| mitotic g1 dna damage checkpoint | GO:0031571 | 17 | 0.596 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.596 | |
| histone modification | GO:0016570 | 251 | 0.584 | |
| dna dependent dna replication | GO:0006261 | 44 | 0.581 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.579 | |
| histone h4 acetylation | GO:0043967 | 47 | 0.572 | |
| negative regulation of g1 s transition of mitotic cell cycle | GO:2000134 | 29 | 0.565 | |
| cellular response to caffeine | GO:0071313 | 3 | 0.551 | |
| recombinational repair | GO:0000725 | 50 | 0.551 | |
| positive regulation of meiotic cell cycle | GO:0051446 | 2 | 0.519 | |
| regulation of cell cycle arrest | GO:0071156 | 36 | 0.510 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 85 | 0.482 | |
| mitotic centrosome separation | GO:0007100 | 1 | 0.480 | |
| g1 dna damage checkpoint | GO:0044783 | 18 | 0.470 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.460 | Fly |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.457 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 118 | 0.455 | |
| mitotic cell cycle checkpoint | GO:0007093 | 68 | 0.447 | |
| meiotic chromosome segregation | GO:0045132 | 4 | 0.442 | Worm |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.441 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.433 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.432 | |
| signal transduction involved in cell cycle checkpoint | GO:0072395 | 16 | 0.419 | |
| positive regulation of cell cycle arrest | GO:0071158 | 23 | 0.406 | |
| intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator | GO:0042771 | 23 | 0.400 | |
| g2 dna damage checkpoint | GO:0031572 | 26 | 0.390 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.381 | |
| mitotic g1 s transition checkpoint | GO:0044819 | 17 | 0.376 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.373 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.372 | |
| endomembrane system organization | GO:0010256 | 196 | 0.363 | |
| zymogen activation | GO:0031638 | 70 | 0.361 | Fly |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.354 | Fly |
| negative regulation of cell cycle g1 s phase transition | GO:1902807 | 29 | 0.349 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.346 | |
| protein ubiquitination | GO:0016567 | 314 | 0.341 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.327 | |
| chemical homeostasis | GO:0048878 | 306 | 0.321 | |
| dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest | GO:0006977 | 9 | 0.318 | |
| dna recombination | GO:0006310 | 77 | 0.318 | |
| dna double strand break processing | GO:0000729 | 10 | 0.315 | |
| lipid biosynthetic process | GO:0008610 | 177 | 0.313 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.309 | |
| dna duplex unwinding | GO:0032508 | 30 | 0.305 | |
| cellular homeostasis | GO:0019725 | 196 | 0.304 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.302 | Fly |
| internal protein amino acid acetylation | GO:0006475 | 101 | 0.289 | |
| nucleotide excision repair | GO:0006289 | 31 | 0.286 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.279 | |
| regulation of mitosis | GO:0007088 | 63 | 0.276 | |
| regulation of cytokinesis | GO:0032465 | 45 | 0.274 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.272 | |
| dna catabolic process | GO:0006308 | 49 | 0.271 | |
| dna catabolic process exonucleolytic | GO:0000738 | 17 | 0.270 | |
| regulation of cell development | GO:0060284 | 161 | 0.268 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.268 | Fly |
| regulation of kinase activity | GO:0043549 | 314 | 0.260 | |
| female gamete generation | GO:0007292 | 2 | 0.252 | |
| signal transduction involved in mitotic g1 dna damage checkpoint | GO:0072431 | 10 | 0.247 | |
| cytokinesis | GO:0000910 | 96 | 0.247 | |
| cell division | GO:0051301 | 168 | 0.238 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.237 | |
| membrane organization | GO:0061024 | 292 | 0.237 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.236 | |
| golgi disassembly | GO:0090166 | 2 | 0.235 | |
| response to caffeine | GO:0031000 | 3 | 0.234 | |
| cellular response to uv | GO:0034644 | 32 | 0.232 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.231 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.224 | Fly |
| cellular response to purine containing compound | GO:0071415 | 3 | 0.221 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.219 | |
| signal transduction involved in dna damage checkpoint | GO:0072422 | 15 | 0.217 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.215 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.213 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.210 | |
| spindle midzone assembly | GO:0051255 | 4 | 0.207 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.206 | |
| protein processing | GO:0016485 | 226 | 0.204 | Fly |
| signal transduction involved in mitotic dna integrity checkpoint | GO:1902403 | 13 | 0.203 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.201 | |
| intracellular signal transduction involved in g1 dna damage checkpoint | GO:1902400 | 10 | 0.192 | |
| dna conformation change | GO:0071103 | 113 | 0.187 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.185 | |
| regeneration | GO:0031099 | 4 | 0.182 | |
| signal transduction involved in mitotic cell cycle checkpoint | GO:0072413 | 13 | 0.181 | |
| response to purine containing compound | GO:0014074 | 40 | 0.180 | |
| regulation of cell cycle g1 s phase transition | GO:1902806 | 42 | 0.179 | |
| response to xenobiotic stimulus | GO:0009410 | 30 | 0.177 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.177 | |
| circadian regulation of gene expression | GO:0032922 | 8 | 0.176 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.176 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.176 | |
| androgen biosynthetic process | GO:0006702 | 3 | 0.172 | |
| peptidyl lysine acetylation | GO:0018394 | 101 | 0.172 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.172 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.172 | |
| cell cycle g1 s phase transition | GO:0044843 | 80 | 0.169 | |
| centrosome separation | GO:0051299 | 3 | 0.159 | |
| single organism membrane organization | GO:0044802 | 268 | 0.158 | |
| blastocyst development | GO:0001824 | 3 | 0.156 | |
| organelle disassembly | GO:1903008 | 9 | 0.151 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 36 | 0.150 | |
| cation homeostasis | GO:0055080 | 189 | 0.150 | |
| peptidyl lysine modification | GO:0018205 | 144 | 0.149 | |
| dna replication | GO:0006260 | 116 | 0.147 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.145 | |
| negative regulation of transcription involved in g1 s transition of mitotic cell cycle | GO:0071930 | 2 | 0.143 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.142 | |
| organelle fission | GO:0048285 | 149 | 0.142 | |
| spindle organization | GO:0007051 | 53 | 0.139 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.139 | |
| protein acylation | GO:0043543 | 138 | 0.139 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.137 | |
| protein catabolic process | GO:0030163 | 325 | 0.134 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.134 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.133 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.131 | |
| regulation of microtubule based process | GO:0032886 | 74 | 0.129 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.128 | |
| cell cycle arrest | GO:0007050 | 71 | 0.124 | |
| cellular response to light stimulus | GO:0071482 | 34 | 0.121 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.121 | Fly |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.119 | |
| meiosis i | GO:0007127 | 4 | 0.118 | |
| actin filament organization | GO:0007015 | 128 | 0.118 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.117 | |
| oocyte differentiation | GO:0009994 | 2 | 0.116 | |
| cellular response to radiation | GO:0071478 | 65 | 0.116 | Fly |
| oocyte maturation | GO:0001556 | 1 | 0.115 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.113 | |
| regulation of centrosome cycle | GO:0046605 | 15 | 0.112 | |
| ion homeostasis | GO:0050801 | 230 | 0.112 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.108 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.108 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.107 | |
| heart development | GO:0007507 | 95 | 0.106 | |
| negative regulation of mitotic metaphase anaphase transition | GO:0045841 | 17 | 0.105 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.104 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.104 | |
| response to hypoxia | GO:0001666 | 96 | 0.103 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.101 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.100 | |
| regulation of cell division | GO:0051302 | 116 | 0.098 | |
| regulation of protein localization | GO:0032880 | 296 | 0.097 | |
| regulation of cell diameter | GO:0060305 | 1 | 0.096 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.095 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.094 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.094 | |
| embryo development | GO:0009790 | 123 | 0.094 | Worm |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.093 | Fly |
| response to abiotic stimulus | GO:0009628 | 336 | 0.092 | Mouse Fly |
| protein acetylation | GO:0006473 | 116 | 0.092 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.091 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.090 | Fly |
| histone phosphorylation | GO:0016572 | 16 | 0.090 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.089 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.088 | |
| regulation of organelle assembly | GO:1902115 | 40 | 0.087 | |
| non recombinational repair | GO:0000726 | 14 | 0.086 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.085 | |
| regulation of double strand break repair | GO:2000779 | 22 | 0.084 | |
| single organism cellular localization | GO:1902580 | 332 | 0.083 | |
| peptidyl threonine modification | GO:0018210 | 45 | 0.082 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.081 | |
| rhythmic behavior | GO:0007622 | 2 | 0.080 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.080 | |
| signal transduction involved in dna integrity checkpoint | GO:0072401 | 15 | 0.078 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.076 | Fly |
| microtubule based process | GO:0007017 | 210 | 0.075 | |
| regulation of signal transduction by p53 class mediator | GO:1901796 | 26 | 0.075 | |
| positive regulation of defense response | GO:0031349 | 87 | 0.074 | |
| meiotic chromosome separation | GO:0051307 | 3 | 0.073 | |
| secretion | GO:0046903 | 254 | 0.073 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.071 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.070 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.070 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.070 | |
| organelle inheritance | GO:0048308 | 2 | 0.069 | |
| morphogenesis of a branching epithelium | GO:0061138 | 20 | 0.069 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.069 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.066 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.066 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.066 | |
| reproductive process | GO:0022414 | 106 | 0.066 | Fly |
| regulation of protein stability | GO:0031647 | 87 | 0.066 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.065 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.065 | |
| nervous system development | GO:0007399 | 293 | 0.063 | |
| response to ionizing radiation | GO:0010212 | 65 | 0.063 | Mouse Fly |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.062 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.062 | |
| negative regulation of response to dna damage stimulus | GO:2001021 | 33 | 0.062 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.061 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.060 | |
| male gonad development | GO:0008584 | 23 | 0.060 | |
| cell development | GO:0048468 | 328 | 0.060 | Fly |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.059 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.059 | |
| regulation of locomotion | GO:0040012 | 329 | 0.059 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.059 | |
| amine metabolic process | GO:0009308 | 44 | 0.057 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.057 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.056 | |
| lipid metabolic process | GO:0006629 | 381 | 0.055 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.055 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.055 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.055 | |
| reciprocal dna recombination | GO:0035825 | 4 | 0.054 | |
| regulation of microtubule cytoskeleton organization | GO:0070507 | 61 | 0.053 | |
| protein polyubiquitination | GO:0000209 | 110 | 0.053 | |
| development of primary sexual characteristics | GO:0045137 | 35 | 0.053 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.052 | |
| regulation of histone acetylation | GO:0035065 | 19 | 0.052 | |
| mitotic sister chromatid segregation | GO:0000070 | 53 | 0.052 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.052 | |
| signal transduction in absence of ligand | GO:0038034 | 22 | 0.051 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.051 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.051 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.051 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.051 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.051 | |
| urogenital system development | GO:0001655 | 65 | 0.050 | |
| regulation of double strand break repair via homologous recombination | GO:0010569 | 11 | 0.049 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.049 | |
| positive regulation of cell division | GO:0051781 | 59 | 0.049 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.049 | |
| limbic system development | GO:0021761 | 3 | 0.048 | |
| maintenance of location | GO:0051235 | 112 | 0.048 | |
| resolution of meiotic recombination intermediates | GO:0000712 | 3 | 0.048 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.048 | |
| dephosphorylation | GO:0016311 | 209 | 0.048 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.048 | |
| reproductive structure development | GO:0048608 | 55 | 0.048 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.047 | |
| reproductive system development | GO:0061458 | 56 | 0.047 | |
| response to drug | GO:0042493 | 81 | 0.047 | |
| protein localization to organelle | GO:0033365 | 280 | 0.046 | |
| response to uv | GO:0009411 | 73 | 0.046 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.046 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.046 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.045 | Fly |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.045 | Fly |
| cellular response to lipid | GO:0071396 | 127 | 0.044 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.044 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.043 | |
| cellular component disassembly | GO:0022411 | 92 | 0.043 | |
| rhythmic process | GO:0048511 | 31 | 0.043 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.043 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.042 | |
| negative regulation of lipid metabolic process | GO:0045833 | 38 | 0.042 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.042 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.041 | Worm |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.041 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 41 | 0.041 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.040 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 83 | 0.039 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.039 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.039 | |
| protein import into nucleus | GO:0006606 | 104 | 0.039 | |
| interleukin 1 production | GO:0032612 | 26 | 0.039 | |
| morphogenesis of a branching structure | GO:0001763 | 21 | 0.038 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.038 | |
| dna catabolic process endonucleolytic | GO:0000737 | 37 | 0.038 | |
| response to light stimulus | GO:0009416 | 87 | 0.038 | |
| angiogenesis | GO:0001525 | 147 | 0.038 | |
| regulation of centrosome duplication | GO:0010824 | 14 | 0.038 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.037 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.037 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.037 | |
| response to toxic substance | GO:0009636 | 37 | 0.036 | |
| apoptotic process involved in morphogenesis | GO:0060561 | 3 | 0.036 | |
| protein maturation | GO:0051604 | 233 | 0.036 | Fly |
| cellular ion homeostasis | GO:0006873 | 168 | 0.036 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.036 | |
| microtubule nucleation | GO:0007020 | 6 | 0.036 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.036 | Fly |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.036 | |
| positive regulation of transport | GO:0051050 | 336 | 0.035 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.035 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 116 | 0.035 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.035 | Fly |
| neuromuscular junction development | GO:0007528 | 3 | 0.034 | |
| positive regulation of cell morphogenesis involved in differentiation | GO:0010770 | 50 | 0.034 | |
| positive regulation of dendrite morphogenesis | GO:0050775 | 3 | 0.034 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.034 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.033 | |
| circadian rhythm | GO:0007623 | 21 | 0.033 | |
| response to reactive oxygen species | GO:0000302 | 61 | 0.033 | |
| triglyceride homeostasis | GO:0070328 | 14 | 0.033 | |
| golgi inheritance | GO:0048313 | 2 | 0.033 | |
| single organism reproductive process | GO:0044702 | 98 | 0.032 | Fly |
| microtubule organizing center organization | GO:0031023 | 62 | 0.032 | |
| circulatory system development | GO:0072359 | 262 | 0.032 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.032 | |
| negative regulation of mitosis | GO:0045839 | 24 | 0.031 | |
| cell adhesion | GO:0007155 | 325 | 0.031 | |
| neutrophil aggregation | GO:0070488 | 2 | 0.031 | |
| response to oxygen levels | GO:0070482 | 100 | 0.031 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.031 | |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.031 | |
| regulation of defense response | GO:0031347 | 154 | 0.030 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.030 | |
| circadian behavior | GO:0048512 | 2 | 0.030 | |
| response to transition metal nanoparticle | GO:1990267 | 29 | 0.030 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.030 | |
| base excision repair | GO:0006284 | 21 | 0.030 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.029 | |
| histone acetylation | GO:0016573 | 93 | 0.029 | |
| protein heterotetramerization | GO:0051290 | 3 | 0.029 | |
| reciprocal meiotic recombination | GO:0007131 | 4 | 0.029 | |
| central nervous system development | GO:0007417 | 123 | 0.029 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.028 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.028 | |
| reproduction | GO:0000003 | 63 | 0.028 | Worm Fly |
| organelle assembly | GO:0070925 | 176 | 0.028 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.028 | |
| centrosome duplication | GO:0051298 | 28 | 0.028 | |
| cell cell signaling | GO:0007267 | 155 | 0.028 | |
| protein oligomerization | GO:0051259 | 173 | 0.028 | |
| oogenesis | GO:0048477 | 2 | 0.028 | |
| response to alkaloid | GO:0043279 | 20 | 0.028 | |
| positive regulation of dna repair | GO:0045739 | 25 | 0.028 | |
| brain development | GO:0007420 | 97 | 0.028 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.027 | |
| positive regulation of fibroblast proliferation | GO:0048146 | 21 | 0.027 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.027 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.027 | |
| gtp metabolic process | GO:0046039 | 239 | 0.027 | |
| negative regulation of cell division | GO:0051782 | 31 | 0.027 | |
| response to fungus | GO:0009620 | 4 | 0.026 | |
| negative regulation of lipid kinase activity | GO:0090219 | 3 | 0.026 | |
| histone h3 k9 modification | GO:0061647 | 11 | 0.026 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.026 | |
| response to lipid | GO:0033993 | 206 | 0.026 | |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.026 | |
| histone serine phosphorylation | GO:0035404 | 4 | 0.026 | |
| protein targeting to nucleus | GO:0044744 | 104 | 0.026 | |
| golgi organization | GO:0007030 | 38 | 0.025 | |
| gonad development | GO:0008406 | 34 | 0.025 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.025 | |
| regulation of circadian rhythm | GO:0042752 | 11 | 0.025 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.025 | |
| cellular response to iron ion | GO:0071281 | 1 | 0.025 | |
| pattern specification process | GO:0007389 | 43 | 0.025 | |
| hippocampus development | GO:0021766 | 1 | 0.025 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.025 | |
| mammary gland development | GO:0030879 | 17 | 0.025 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.025 | |
| centrosome organization | GO:0051297 | 58 | 0.025 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.024 | |
| regulation of protein dephosphorylation | GO:0035304 | 18 | 0.024 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.024 | |
| regulation of dna damage response signal transduction by p53 class mediator | GO:0043516 | 20 | 0.024 | |
| lens development in camera type eye | GO:0002088 | 2 | 0.024 | |
| glycogen biosynthetic process | GO:0005978 | 16 | 0.024 | |
| negative regulation of glycoprotein metabolic process | GO:1903019 | 8 | 0.024 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.024 | |
| adherens junction organization | GO:0034332 | 36 | 0.023 | |
| glycerolipid metabolic process | GO:0046486 | 107 | 0.023 | |
| protein deubiquitination | GO:0016579 | 79 | 0.023 | |
| protein destabilization | GO:0031648 | 12 | 0.023 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 19 | 0.023 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.023 | |
| mitotic nuclear division | GO:0007067 | 119 | 0.023 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.022 | |
| positive regulation of cytokinesis | GO:0032467 | 29 | 0.022 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.022 | |
| cell morphogenesis | GO:0000902 | 296 | 0.022 | |
| gtp catabolic process | GO:0006184 | 237 | 0.022 | |
| regulation of cellular component size | GO:0032535 | 82 | 0.022 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.022 | Fly |
| regulation of viral process | GO:0050792 | 103 | 0.022 | |
| oocyte development | GO:0048599 | 1 | 0.022 | |
| actin filament bundle assembly | GO:0051017 | 54 | 0.022 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.022 | |
| intracellular protein transport | GO:0006886 | 270 | 0.022 | |
| centrosome cycle | GO:0007098 | 32 | 0.022 | |
| protein targeting | GO:0006605 | 187 | 0.022 | |
| negative regulation of g2 m transition of mitotic cell cycle | GO:0010972 | 9 | 0.022 | |
| regulation of protein transport | GO:0051223 | 213 | 0.021 | |
| regulation of transcription by chromatin organization | GO:0034401 | 1 | 0.021 | |
| meiotic nuclear division | GO:0007126 | 10 | 0.021 | Worm |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.021 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.021 | |
| peptidyl tyrosine dephosphorylation | GO:0035335 | 36 | 0.021 | |
| oxidation reduction process | GO:0055114 | 396 | 0.021 | |
| regulation of cell substrate adhesion | GO:0010810 | 68 | 0.021 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.021 | |
| interleukin 1 alpha secretion | GO:0050703 | 1 | 0.021 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.021 | Fly |
| nucleus organization | GO:0006997 | 28 | 0.020 | |
| response to steroid hormone | GO:0048545 | 80 | 0.020 | |
| regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter | GO:0072366 | 1 | 0.020 | |
| endocytosis | GO:0006897 | 159 | 0.020 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.020 | |
| defense response to fungus | GO:0050832 | 4 | 0.020 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.020 | |
| cell cycle g2 m phase transition | GO:0044839 | 43 | 0.020 | |
| regulation of nervous system development | GO:0051960 | 88 | 0.020 | |
| chromosome separation | GO:0051304 | 23 | 0.020 | |
| positive regulation of dna damage response signal transduction by p53 class mediator | GO:0043517 | 8 | 0.020 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.020 | |
| positive regulation of multi organism process | GO:0043902 | 56 | 0.020 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 83 | 0.020 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.020 | |
| negative regulation of cell cycle g2 m phase transition | GO:1902750 | 10 | 0.020 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.020 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.019 | |
| negative regulation of protein ubiquitination | GO:0031397 | 35 | 0.019 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.019 | |
| chromatin mediated maintenance of transcription | GO:0048096 | 2 | 0.019 | |
| locomotory behavior | GO:0007626 | 1 | 0.019 | |
| tube development | GO:0035295 | 125 | 0.019 | |
| centriole replication | GO:0007099 | 13 | 0.019 | |
| hexose metabolic process | GO:0019318 | 55 | 0.019 | |
| regulation of neuron projection development | GO:0010975 | 57 | 0.019 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.019 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.019 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.019 | Fly |
| cardiac chamber development | GO:0003205 | 30 | 0.019 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.019 | Fly |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.018 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 60 | 0.018 | |
| cation transport | GO:0006812 | 331 | 0.018 | |
| cell growth | GO:0016049 | 160 | 0.018 | |
| renal system development | GO:0072001 | 63 | 0.018 | |
| negative regulation of neural precursor cell proliferation | GO:2000178 | 1 | 0.018 | |
| regulation of neuron differentiation | GO:0045664 | 70 | 0.018 | |
