IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

DDX23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

(Aliases: U5-100K,prp28,PRPF28,MGC8416,U5-100KD)

HGNC: 17347
HPRD: 09908
Entrez: 9416
MIM: 612172
Ensembl: ENSG00000174243
UniProtKB: Q9BUQ8
UniProtKB: A0A024R0Z3
UniProtKB: B3KY11

Process Predictions
Disease Predictions

DDX23 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
post embryonic development	GO:0009791	2	0.570	Worm
mrna splicing via spliceosome	GO:0000398	89	0.363
regulation of cell cycle	GO:0051726	393	0.285	Worm
ribonucleoside catabolic process	GO:0042454	406	0.247
rna splicing	GO:0008380	131	0.244
glycosyl compound catabolic process	GO:1901658	413	0.237
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.232
vesicle mediated transport	GO:0016192	371	0.225
regulation of meiotic cell cycle	GO:0051445	4	0.209	Worm
segmentation	GO:0035282	4	0.180
sex differentiation	GO:0007548	45	0.167	Worm
purine nucleotide catabolic process	GO:0006195	405	0.164
chromatin organization	GO:0006325	351	0.158
dna conformation change	GO:0071103	113	0.155
rna splicing via transesterification reactions	GO:0000375	90	0.149
nucleoside monophosphate catabolic process	GO:0009125	159	0.144
purine ribonucleoside catabolic process	GO:0046130	398	0.140
nucleoside monophosphate metabolic process	GO:0009123	191	0.138
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.137
ribonucleotide catabolic process	GO:0009261	405	0.131
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.131
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.129
nucleoside triphosphate catabolic process	GO:0009143	394	0.127
histone modification	GO:0016570	251	0.120
reproductive structure development	GO:0048608	55	0.120	Worm
nucleoside catabolic process	GO:0009164	408	0.118
embryo development	GO:0009790	123	0.115	Worm
cellular macromolecular complex assembly	GO:0034622	324	0.110
nucleoside triphosphate metabolic process	GO:0009141	422	0.110
organophosphate catabolic process	GO:0046434	430	0.105
spliceosomal snrnp assembly	GO:0000387	28	0.104
purine containing compound catabolic process	GO:0072523	411	0.104
purine ribonucleotide catabolic process	GO:0009154	404	0.103
nucleotide catabolic process	GO:0009166	408	0.102
spliceosomal tri snrnp complex assembly	GO:0000244	7	0.100
atp metabolic process	GO:0046034	176	0.097
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	89	0.095
multicellular organismal aging	GO:0010259	3	0.091
purine ribonucleoside metabolic process	GO:0046128	437	0.089
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.085
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.080
immune system development	GO:0002520	195	0.078
nucleoside phosphate catabolic process	GO:1901292	412	0.077
atp catabolic process	GO:0006200	157	0.076
regulation of viral process	GO:0050792	103	0.076
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.076
dna replication	GO:0006260	116	0.074
organelle fission	GO:0048285	149	0.072	Worm
purine nucleoside catabolic process	GO:0006152	398	0.070
hematopoietic or lymphoid organ development	GO:0048534	186	0.068
oocyte differentiation	GO:0009994	2	0.067
macromolecule methylation	GO:0043414	97	0.066
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.065
mitotic cell cycle process	GO:1903047	286	0.065
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.064
oocyte development	GO:0048599	1	0.064
methylation	GO:0032259	106	0.064
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.063
cellular response to dna damage stimulus	GO:0006974	379	0.062
viral process	GO:0016032	146	0.062
determination of adult lifespan	GO:0008340	2	0.062
oogenesis	GO:0048477	2	0.060
viral life cycle	GO:0019058	132	0.058
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.058
dna repair	GO:0006281	198	0.056
female gamete generation	GO:0007292	2	0.055
covalent chromatin modification	GO:0016569	254	0.054
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.053
chromatin modification	GO:0016568	298	0.052
mrna metabolic process	GO:0016071	175	0.049
regulation of meiosis	GO:0040020	3	0.049	Worm
behavior	GO:0007610	112	0.047
gonad development	GO:0008406	34	0.044	Worm
reproduction	GO:0000003	63	0.044	Worm
reproductive system development	GO:0061458	56	0.041	Worm
dna geometric change	GO:0032392	32	0.040
biological adhesion	GO:0022610	331	0.040
neurogenesis	GO:0022008	169	0.040	Fly
mitotic cell cycle	GO:0000278	326	0.039
anterior posterior axis specification	GO:0009948	2	0.038
embryo development ending in birth or egg hatching	GO:0009792	34	0.038	Worm
histone methylation	GO:0016571	60	0.038
mrna processing	GO:0006397	133	0.038
double strand break repair	GO:0006302	101	0.038
symbiosis encompassing mutualism through parasitism	GO:0044403	156	0.037
reproductive process	GO:0022414	106	0.037	Worm
amine metabolic process	GO:0009308	44	0.036
dna dependent dna replication	GO:0006261	44	0.035
mitotic nuclear division	GO:0007067	119	0.035
endocytosis	GO:0006897	159	0.034
interspecies interaction between organisms	GO:0044419	156	0.033
rna interference	GO:0016246	4	0.033
cytoplasmic transport	GO:0016482	379	0.033
nervous system development	GO:0007399	293	0.032	Fly
dna duplex unwinding	GO:0032508	30	0.031
regulation of gene expression epigenetic	GO:0040029	73	0.031
regulation of cell cycle process	GO:0010564	266	0.031	Worm
epithelium development	GO:0060429	227	0.030
thymus development	GO:0048538	3	0.029
developmental process involved in reproduction	GO:0003006	66	0.028	Worm
regulation of cell division	GO:0051302	116	0.028	Worm
protein alkylation	GO:0008213	74	0.028
response to organic cyclic compound	GO:0014070	204	0.028
nuclear export	GO:0051168	69	0.027
hemopoiesis	GO:0030097	180	0.027
cellular protein complex assembly	GO:0043623	188	0.027
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	109	0.027
rna processing	GO:0006396	255	0.027
single organism reproductive process	GO:0044702	98	0.027	Worm
nucleocytoplasmic transport	GO:0006913	176	0.026
ribonucleoprotein complex assembly	GO:0022618	78	0.026
mrna transport	GO:0051028	30	0.026
cell cycle phase transition	GO:0044770	173	0.026
cellular response to organic cyclic compound	GO:0071407	127	0.026
meiotic cell cycle	GO:0051321	13	0.026	Worm
response to abiotic stimulus	GO:0009628	336	0.025
negative regulation of protein metabolic process	GO:0051248	391	0.025
cellular amino acid metabolic process	GO:0006520	116	0.025
protein localization to organelle	GO:0033365	280	0.025
regulation of cellular amine metabolic process	GO:0033238	11	0.025
molting cycle	GO:0042303	28	0.024
meiosis i	GO:0007127	4	0.024
establishment of nucleus localization	GO:0040023	1	0.024
intracellular protein transport	GO:0006886	270	0.024
protein localization to nucleus	GO:0034504	136	0.023
blastoderm segmentation	GO:0007350	2	0.023
organelle localization	GO:0051640	84	0.023
negative regulation of cell differentiation	GO:0045596	171	0.023
nucleus localization	GO:0051647	1	0.022
cellular component morphogenesis	GO:0032989	314	0.022
regulation of viral genome replication	GO:0045069	48	0.022
chordate embryonic development	GO:0043009	34	0.022
cellular amine metabolic process	GO:0044106	41	0.022
histone h3 k4 methylation	GO:0051568	27	0.021
rna localization	GO:0006403	41	0.021
regulation of intracellular transport	GO:0032386	195	0.021
carbohydrate derivative biosynthetic process	GO:1901137	207	0.020
negative regulation of cellular protein metabolic process	GO:0032269	353	0.020
ribonucleoprotein complex biogenesis	GO:0022613	116	0.020
defense response	GO:0006952	315	0.019
anterior posterior axis specification embryo	GO:0008595	2	0.019
single organism cellular localization	GO:1902580	332	0.019
dna recombination	GO:0006310	77	0.019
regulation of chromosome organization	GO:0033044	103	0.018
leukocyte activation	GO:0045321	164	0.018
rna transport	GO:0050658	39	0.018
cardiovascular system development	GO:0072358	262	0.018
response to cytokine	GO:0034097	232	0.017
nuclear division	GO:0000280	128	0.017	Worm
cell morphogenesis	GO:0000902	296	0.017
establishment of rna localization	GO:0051236	39	0.017
cell adhesion	GO:0007155	325	0.017
maintenance of location	GO:0051235	112	0.016
multi organism cellular process	GO:0044764	156	0.016
ribonucleoprotein complex subunit organization	GO:0071826	81	0.016
receptor mediated endocytosis	GO:0006898	84	0.016
gene silencing	GO:0016458	49	0.016
nucleotide excision repair dna incision	GO:0033683	7	0.016
protein targeting to nucleus	GO:0044744	104	0.016
protein targeting	GO:0006605	187	0.016
aging	GO:0007568	66	0.016
blastocyst development	GO:0001824	3	0.016
negative regulation of developmental process	GO:0051093	247	0.015
rna export from nucleus	GO:0006405	33	0.015
regulation of chromatin organization	GO:1902275	56	0.015
nitrogen compound transport	GO:0071705	191	0.015
regulation of histone modification	GO:0031056	47	0.015
microtubule based process	GO:0007017	210	0.015
ribosomal subunit export from nucleus	GO:0000054	4	0.015
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	125	0.014
circulatory system development	GO:0072359	262	0.014
regulation of multi organism process	GO:0043900	157	0.014
cellular component disassembly	GO:0022411	92	0.014
meiotic nuclear division	GO:0007126	10	0.014	Worm
meiotic chromosome segregation	GO:0045132	4	0.014
establishment of protein localization to organelle	GO:0072594	172	0.014
regulation of lymphocyte activation	GO:0051249	103	0.014
cell development	GO:0048468	328	0.014	Worm
regulation of nucleotide metabolic process	GO:0006140	269	0.014
regulation of nucleoside metabolic process	GO:0009118	209	0.013
regulation of purine nucleotide catabolic process	GO:0033121	205	0.013
negative regulation of cell cycle	GO:0045786	193	0.013
development of primary sexual characteristics	GO:0045137	35	0.013	Worm
cell division	GO:0051301	168	0.013	Worm
regulation of mitotic cell cycle	GO:0007346	189	0.013
protein acylation	GO:0043543	138	0.013
small gtpase mediated signal transduction	GO:0007264	78	0.013
ras protein signal transduction	GO:0007265	73	0.013
central nervous system development	GO:0007417	123	0.013
neurological system process	GO:0050877	163	0.013
negative regulation of catalytic activity	GO:0043086	335	0.013
lymphocyte activation	GO:0046649	133	0.013
dna templated transcription termination	GO:0006353	3	0.013
regulation of cellular ketone metabolic process	GO:0010565	50	0.012
positive regulation of lymphocyte activation	GO:0051251	73	0.012
multicellular organismal reproductive process	GO:0048609	40	0.012	Worm
endomembrane system organization	GO:0010256	196	0.012
regulation of mrna metabolic process	GO:1903311	53	0.012
mitotic cell cycle phase transition	GO:0044772	162	0.012
production of mirnas involved in gene silencing by mirna	GO:0035196	12	0.012
regulation of protein transport	GO:0051223	213	0.012
base excision repair	GO:0006284	21	0.012
microtubule cytoskeleton organization	GO:0000226	176	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.012
regulation of dna recombination	GO:0000018	23	0.012
tripartite regional subdivision	GO:0007351	2	0.012
positive regulation of nfat protein import into nucleus	GO:0051533	3	0.012
histone lysine methylation	GO:0034968	50	0.012
regulation of protein localization	GO:0032880	296	0.012
pharynx development	GO:0060465	1	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	156	0.012
cellular ketone metabolic process	GO:0042180	80	0.012
positive regulation of organelle organization	GO:0010638	195	0.011
posttranscriptional regulation of gene expression	GO:0010608	213	0.011
regulation of cytoplasmic transport	GO:1903649	149	0.011
peptidyl lysine acetylation	GO:0018394	101	0.011
negative regulation of phosphate metabolic process	GO:0045936	267	0.011
positive regulation of developmental process	GO:0051094	314	0.011
positive regulation of cell activation	GO:0050867	81	0.011
mapk cascade	GO:0000165	288	0.011
multi organism reproductive process	GO:0044703	54	0.011	Worm
regulation of protein stability	GO:0031647	87	0.011
snorna metabolic process	GO:0016074	1	0.011
response to oxygen containing compound	GO:1901700	369	0.011
positive regulation of leukocyte activation	GO:0002696	80	0.011
ossification	GO:0001503	121	0.011
regulation of mapk cascade	GO:0043408	262	0.011
innate immune response	GO:0045087	178	0.011
regulation of dna metabolic process	GO:0051052	153	0.010
negative regulation of phosphorus metabolic process	GO:0010563	267	0.010
response to fungus	GO:0009620	4	0.010
positive regulation of cellular component biogenesis	GO:0044089	158	0.010
positive regulation of chromatin modification	GO:1903310	30	0.010
response to other organism	GO:0051707	261	0.010
nuclear transport	GO:0051169	179	0.010
defense response to other organism	GO:0098542	129	0.010
nuclear import	GO:0051170	106	0.010
regulation of purine nucleotide metabolic process	GO:1900542	264	0.010
positive regulation of viral process	GO:0048524	37	0.010
posttranscriptional gene silencing by rna	GO:0035194	25	0.010
production of small rna involved in gene silencing by rna	GO:0070918	13	0.010

DDX23 disease predictions

Disease	DO term ID	Size	Probability
eye and adnexa disease	DOID:1492	150	0.556
sensory system disease	DOID:0050155	203	0.556
nervous system disease	DOID:863	431	0.556
eye disease	DOID:5614	149	0.049
retinal disease	DOID:5679	118	0.039
retinal degeneration	DOID:8466	89	0.039
neurodegenerative disease	DOID:1289	102	0.018
central nervous system disease	DOID:331	186	0.018
retinitis pigmentosa	DOID:10584	51	0.011
disease of mental health	DOID:150	70	0.011
musculoskeletal system disease	DOID:17	223	0.010

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