| multicellular organismal aging | GO:0010259 | 3 | 0.383 | |
| female gamete generation | GO:0007292 | 2 | 0.282 | |
| translation | GO:0006412 | 132 | 0.204 | Human |
| determination of adult lifespan | GO:0008340 | 2 | 0.193 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.182 | |
| post embryonic development | GO:0009791 | 2 | 0.159 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.126 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.104 | |
| oxidation reduction process | GO:0055114 | 396 | 0.102 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.096 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.095 | |
| oogenesis | GO:0048477 | 2 | 0.095 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.090 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.088 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.083 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.083 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.082 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.079 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.075 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.066 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.065 | |
| cell development | GO:0048468 | 328 | 0.065 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.064 | |
| ribose phosphate biosynthetic process | GO:0046390 | 82 | 0.063 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.061 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.060 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.059 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.057 | |
| system process | GO:0003008 | 349 | 0.056 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.054 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.054 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.053 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.053 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.052 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.052 | |
| atp metabolic process | GO:0046034 | 176 | 0.051 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.049 | |
| trna aminoacylation for protein translation | GO:0006418 | 8 | 0.048 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.047 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.046 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.044 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.043 | |
| ncrna metabolic process | GO:0034660 | 108 | 0.042 | |
| protein ubiquitination | GO:0016567 | 314 | 0.041 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.041 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.041 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.040 | |
| epithelium development | GO:0060429 | 227 | 0.039 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.039 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.039 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.038 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.038 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.036 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.035 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.034 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.034 | |
| maintenance of location | GO:0051235 | 112 | 0.033 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.033 | |
| rna processing | GO:0006396 | 255 | 0.033 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 79 | 0.033 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.032 | |
| tissue morphogenesis | GO:0048729 | 96 | 0.031 | |
| amino acid activation | GO:0043038 | 12 | 0.031 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 109 | 0.031 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.030 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.030 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.030 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.029 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.029 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.029 | |
| single organism cellular localization | GO:1902580 | 332 | 0.029 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.029 | |
| amine metabolic process | GO:0009308 | 44 | 0.029 | |
| embryo development | GO:0009790 | 123 | 0.029 | |
| demethylation | GO:0070988 | 37 | 0.028 | |
| ribonucleoprotein complex biogenesis | GO:0022613 | 116 | 0.028 | |
| microtubule based process | GO:0007017 | 210 | 0.028 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.028 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.028 | |
| reproductive system development | GO:0061458 | 56 | 0.028 | |
| chromatin organization | GO:0006325 | 351 | 0.028 | |
| purine containing compound biosynthetic process | GO:0072522 | 88 | 0.028 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.027 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.027 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.027 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.027 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.026 | |
| aging | GO:0007568 | 66 | 0.026 | |
| reproductive structure development | GO:0048608 | 55 | 0.026 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.026 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.026 | |
| protein catabolic process | GO:0030163 | 325 | 0.026 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.026 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.025 | |
| single organism reproductive process | GO:0044702 | 98 | 0.025 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.024 | |
| regulation of transcription during mitosis | GO:0045896 | 2 | 0.024 | |
| histone modification | GO:0016570 | 251 | 0.024 | |
| epithelial tube morphogenesis | GO:0060562 | 38 | 0.023 | |
| trna aminoacylation | GO:0043039 | 12 | 0.023 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.023 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.023 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.023 | |
| growth | GO:0040007 | 202 | 0.022 | |
| regulation of protein localization | GO:0032880 | 296 | 0.022 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.022 | |
| gtp metabolic process | GO:0046039 | 239 | 0.022 | |
| endocytosis | GO:0006897 | 159 | 0.022 | |
| cellular homeostasis | GO:0019725 | 196 | 0.021 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 158 | 0.021 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.021 | |
| protein localization to organelle | GO:0033365 | 280 | 0.021 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.021 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.021 | |
| sex differentiation | GO:0007548 | 45 | 0.021 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.020 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.020 | |
| nervous system development | GO:0007399 | 293 | 0.020 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.020 | |
| cell projection organization | GO:0030030 | 252 | 0.020 | |
| cellular response to lipid | GO:0071396 | 127 | 0.020 | |
| segmentation | GO:0035282 | 4 | 0.020 | |
| regulation of translation | GO:0006417 | 89 | 0.019 | |
| gonad development | GO:0008406 | 34 | 0.019 | |
| coenzyme metabolic process | GO:0006732 | 65 | 0.019 | |
| translational initiation | GO:0006413 | 48 | 0.019 | Human |
| cell adhesion | GO:0007155 | 325 | 0.019 | |
| intracellular protein transport | GO:0006886 | 270 | 0.019 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.019 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.019 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.019 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.019 | |
| cofactor metabolic process | GO:0051186 | 87 | 0.019 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.019 | |
| dna demethylation | GO:0080111 | 12 | 0.019 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.018 | |
| protein processing | GO:0016485 | 226 | 0.018 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.018 | |
| tube development | GO:0035295 | 125 | 0.018 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.018 | |
| embryonic morphogenesis | GO:0048598 | 85 | 0.018 | |
| regulation of growth | GO:0040008 | 165 | 0.018 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.018 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.018 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.018 | |
| hemopoiesis | GO:0030097 | 180 | 0.018 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.018 | |
| regulation of transcription from rna polymerase ii promoter mitotic | GO:0046021 | 1 | 0.018 | |
| chromatin modification | GO:0016568 | 298 | 0.018 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.018 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.018 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.018 | |
| single organism nuclear import | GO:1902593 | 104 | 0.018 | |
| mammary gland morphogenesis | GO:0060443 | 2 | 0.018 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.018 | |
| rna phosphodiester bond hydrolysis | GO:0090501 | 35 | 0.017 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.017 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.017 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.017 | |
| cell morphogenesis | GO:0000902 | 296 | 0.017 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.017 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.017 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.017 | |
| rrna processing | GO:0006364 | 35 | 0.017 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.017 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.017 | |
| positive regulation of transport | GO:0051050 | 336 | 0.017 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.017 | |
| gtp catabolic process | GO:0006184 | 237 | 0.017 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.017 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.017 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.017 | |
| mrna metabolic process | GO:0016071 | 175 | 0.016 | |
| regulation of cell division | GO:0051302 | 116 | 0.016 | |
| glycosyl compound biosynthetic process | GO:1901659 | 27 | 0.016 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 81 | 0.016 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.016 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.016 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.016 | |
| lipid localization | GO:0010876 | 106 | 0.016 | |
| regulation of oxidative phosphorylation | GO:0002082 | 3 | 0.016 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.016 | |
| rna splicing | GO:0008380 | 131 | 0.016 | |
| trna metabolic process | GO:0006399 | 35 | 0.016 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.016 | |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.015 | |
| reproductive process | GO:0022414 | 106 | 0.015 | |
| defense response | GO:0006952 | 315 | 0.015 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.015 | |
| organelle assembly | GO:0070925 | 176 | 0.015 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.015 | |
| regulation of protein transport | GO:0051223 | 213 | 0.015 | |
| rna 3 end processing | GO:0031123 | 35 | 0.015 | |
| ossification | GO:0001503 | 121 | 0.015 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.015 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.015 | |
| protein acetylation | GO:0006473 | 116 | 0.015 | |
| gmp metabolic process | GO:0046037 | 4 | 0.015 | |
| rna interference | GO:0016246 | 4 | 0.015 | |
| immune system development | GO:0002520 | 195 | 0.015 | |
| ribonucleotide biosynthetic process | GO:0009260 | 81 | 0.015 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.014 | |
| protein maturation | GO:0051604 | 233 | 0.014 | |
| protein oligomerization | GO:0051259 | 173 | 0.014 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.014 | |
| rna modification | GO:0009451 | 27 | 0.014 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.014 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.014 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.014 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.014 | |
| dna repair | GO:0006281 | 198 | 0.014 | |
| atp catabolic process | GO:0006200 | 157 | 0.014 | |
| regulation of epithelial cell proliferation | GO:0050678 | 113 | 0.014 | |
| neuron projection development | GO:0031175 | 106 | 0.014 | |
| sulfur compound metabolic process | GO:0006790 | 101 | 0.014 | |
| reproduction | GO:0000003 | 63 | 0.014 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.014 | |
| biological adhesion | GO:0022610 | 331 | 0.014 | |
| ribosome biogenesis | GO:0042254 | 48 | 0.014 | |
| dephosphorylation | GO:0016311 | 209 | 0.014 | |
| mitochondrion organization | GO:0007005 | 156 | 0.014 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.014 | |
| cardiovascular system development | GO:0072358 | 262 | 0.014 | |
| neurogenesis | GO:0022008 | 169 | 0.014 | |
| single organism membrane organization | GO:0044802 | 268 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.013 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.013 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.013 | |
| excretion | GO:0007588 | 9 | 0.013 | |
| circulatory system development | GO:0072359 | 262 | 0.013 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.013 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.013 | |
| purine nucleotide biosynthetic process | GO:0006164 | 84 | 0.013 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.013 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.013 | |
| cation transport | GO:0006812 | 331 | 0.013 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.013 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.013 | |
| secretion by cell | GO:0032940 | 226 | 0.013 | |
| cofactor biosynthetic process | GO:0051188 | 31 | 0.013 | |
| maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna | GO:0000466 | 2 | 0.013 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.013 | |
| protein acylation | GO:0043543 | 138 | 0.013 | |
| secretion | GO:0046903 | 254 | 0.013 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.013 | |
| cellular modified amino acid metabolic process | GO:0006575 | 64 | 0.012 | |
| response to hormone | GO:0009725 | 175 | 0.012 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.012 | |
| actin filament based process | GO:0030029 | 224 | 0.012 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.012 | |
| organ morphogenesis | GO:0009887 | 147 | 0.012 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.012 | |
| regulation of cell motility | GO:2000145 | 299 | 0.012 | |
| osteoblast differentiation | GO:0001649 | 92 | 0.012 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.012 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.012 | |
| immune response | GO:0006955 | 307 | 0.012 | |
| methylation | GO:0032259 | 106 | 0.012 | |
| regulation of cell development | GO:0060284 | 161 | 0.012 | |
| negative regulation of organelle organization | GO:0010639 | 126 | 0.012 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.012 | |
| macromolecule methylation | GO:0043414 | 97 | 0.012 | |
| generation of precursor metabolites and energy | GO:0006091 | 68 | 0.012 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.012 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.012 | |
| cell projection morphogenesis | GO:0048858 | 129 | 0.012 | |
| negative regulation of transport | GO:0051051 | 176 | 0.011 | |
| toxin transport | GO:1901998 | 4 | 0.011 | |
| photoreceptor cell differentiation | GO:0046530 | 2 | 0.011 | |
| protein targeting | GO:0006605 | 187 | 0.011 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.011 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.011 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.011 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.011 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 102 | 0.011 | |
| regulation of cell migration | GO:0030334 | 289 | 0.011 | |
| positive regulation of dna repair | GO:0045739 | 25 | 0.011 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.011 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.011 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 48 | 0.011 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.011 | |
| immune effector process | GO:0002252 | 159 | 0.011 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.011 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.011 | |
| ncrna processing | GO:0034470 | 83 | 0.011 | |
| embryonic eye morphogenesis | GO:0048048 | 2 | 0.011 | |
| regulation of cell cycle phase transition | GO:1901987 | 126 | 0.011 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.011 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.011 | |
| vasculature development | GO:0001944 | 181 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.011 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.011 | |
| response to cytokine | GO:0034097 | 232 | 0.011 | |
| metal ion transport | GO:0030001 | 272 | 0.011 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 43 | 0.011 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.010 | |
| lipid metabolic process | GO:0006629 | 381 | 0.010 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.010 | |
| neuron differentiation | GO:0030182 | 138 | 0.010 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 0.010 | |
| positive regulation of camp metabolic process | GO:0030816 | 41 | 0.010 | |
| tube morphogenesis | GO:0035239 | 95 | 0.010 | |
| regulation of locomotion | GO:0040012 | 329 | 0.010 | |
| cell division | GO:0051301 | 168 | 0.010 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.010 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 25 | 0.010 | |