| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 52 | 0.984 | Human |
| actin filament organization | GO:0007015 | 128 | 0.983 | Human Fly |
| actin filament based process | GO:0030029 | 224 | 0.977 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.971 | Human |
| cytokine production | GO:0001816 | 247 | 0.966 | Human |
| interferon gamma production | GO:0032609 | 39 | 0.956 | Human |
| vesicle mediated transport | GO:0016192 | 371 | 0.953 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.949 | Human |
| response to external biotic stimulus | GO:0043207 | 261 | 0.939 | Mouse |
| regulation of cytokine production | GO:0001817 | 232 | 0.934 | Human |
| regulation of actin cytoskeleton organization | GO:0032956 | 116 | 0.927 | |
| actin polymerization or depolymerization | GO:0008154 | 56 | 0.924 | Fly |
| positive regulation of lipid metabolic process | GO:0045834 | 50 | 0.920 | Human |
| regulation of cell migration | GO:0030334 | 289 | 0.915 | Human |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.904 | Human |
| response to biotic stimulus | GO:0009607 | 276 | 0.899 | Mouse |
| response to other organism | GO:0051707 | 261 | 0.897 | Mouse |
| regulation of protein oligomerization | GO:0032459 | 26 | 0.882 | Human |
| cell activation | GO:0001775 | 213 | 0.878 | Human |
| integrin mediated signaling pathway | GO:0007229 | 32 | 0.875 | Human |
| caveolin mediated endocytosis | GO:0072584 | 4 | 0.869 | Human |
| positive regulation of response to interferon gamma | GO:0060332 | 2 | 0.868 | Human |
| memory | GO:0007613 | 3 | 0.863 | Fly |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.860 | Human Fly |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.854 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 51 | 0.841 | Human |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.837 | |
| actin filament polymerization | GO:0030041 | 45 | 0.834 | |
| amide transport | GO:0042886 | 76 | 0.834 | Human |
| regulation of actin polymerization or depolymerization | GO:0008064 | 56 | 0.834 | Fly |
| zinc ion homeostasis | GO:0055069 | 12 | 0.824 | Human |
| leukocyte activation | GO:0045321 | 164 | 0.820 | Human |
| cellular amine metabolic process | GO:0044106 | 41 | 0.803 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.790 | Human |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.790 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.786 | Human |
| tyrosine phosphorylation of stat3 protein | GO:0042503 | 20 | 0.773 | Human |
| defense response | GO:0006952 | 315 | 0.763 | Human Mouse |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.754 | Human |
| lymphocyte activation | GO:0046649 | 133 | 0.749 | Human |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.747 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.745 | Human |
| positive regulation of cell motility | GO:2000147 | 177 | 0.741 | |
| regulation of leukocyte migration | GO:0002685 | 63 | 0.739 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.737 | Human |
| regulation of cell motility | GO:2000145 | 299 | 0.736 | Human |
| t cell activation | GO:0042110 | 99 | 0.734 | Human |
| regulation of caveolin mediated endocytosis | GO:2001286 | 2 | 0.726 | Human |
| positive regulation of t cell activation | GO:0050870 | 54 | 0.723 | Human |
| cell chemotaxis | GO:0060326 | 112 | 0.722 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.717 | Human |
| positive regulation of cytoskeleton organization | GO:0051495 | 83 | 0.716 | |
| regulation of defense response | GO:0031347 | 154 | 0.713 | Human |
| endocytosis | GO:0006897 | 159 | 0.712 | |
| actin filament bundle assembly | GO:0051017 | 54 | 0.705 | Human Fly |
| jak stat cascade | GO:0007259 | 46 | 0.704 | Human |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.701 | Human |
| peptide secretion | GO:0002790 | 51 | 0.700 | Human |
| leukocyte differentiation | GO:0002521 | 98 | 0.700 | Human |
| regulation of protein transport | GO:0051223 | 213 | 0.688 | |
| cell development | GO:0048468 | 328 | 0.678 | Human Fly |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.673 | Human |
| secretion by cell | GO:0032940 | 226 | 0.669 | Human |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.668 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.663 | Human |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.662 | |
| peptide transport | GO:0015833 | 74 | 0.660 | Human |
| hormone transport | GO:0009914 | 68 | 0.658 | Human |
| immune system development | GO:0002520 | 195 | 0.657 | Human |
| amine metabolic process | GO:0009308 | 44 | 0.651 | |
| oogenesis | GO:0048477 | 2 | 0.641 | Fly |
| regulation of secretion by cell | GO:1903530 | 177 | 0.641 | Human |
| positive regulation of phosphatidylinositol 3 kinase signaling | GO:0014068 | 28 | 0.640 | Human |
| chemotaxis | GO:0006935 | 157 | 0.635 | Fly |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.634 | Human |
| positive regulation of interferon gamma production | GO:0032729 | 26 | 0.632 | Human |
| positive regulation of cell death | GO:0010942 | 263 | 0.628 | Human |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.627 | Human |
| regulation of actin filament based process | GO:0032970 | 141 | 0.612 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.611 | |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.609 | Human |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.603 | |
| hormone secretion | GO:0046879 | 65 | 0.594 | Human |
| positive regulation of cell activation | GO:0050867 | 81 | 0.583 | Human |
| positive regulation of cytokine mediated signaling pathway | GO:0001961 | 12 | 0.581 | Human |
| negative regulation of developmental process | GO:0051093 | 247 | 0.580 | Fly |
| regulation of lymphocyte activation | GO:0051249 | 103 | 0.572 | Human |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.571 | Human Fly |
| regulation of actin filament polymerization | GO:0030833 | 50 | 0.569 | |
| dephosphorylation | GO:0016311 | 209 | 0.566 | Human |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.554 | Human |
| regulation of hormone secretion | GO:0046883 | 57 | 0.553 | Human |
| regulation of insulin secretion | GO:0050796 | 33 | 0.541 | Human |
| regulation of secretion | GO:0051046 | 194 | 0.540 | Human |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.534 | Human |
| myeloid leukocyte migration | GO:0097529 | 62 | 0.534 | |
| regulation of organelle assembly | GO:1902115 | 40 | 0.531 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.527 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.526 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.524 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.523 | Human |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.522 | Human |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.515 | Human |
| metal ion homeostasis | GO:0055065 | 169 | 0.514 | Human |
| regulation of mast cell degranulation | GO:0043304 | 3 | 0.506 | |
| regulation of anatomical structure size | GO:0090066 | 101 | 0.505 | Fly |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.505 | Human |
| regulation of protein localization | GO:0032880 | 296 | 0.498 | |
| long term memory | GO:0007616 | 2 | 0.497 | Fly |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.492 | Human |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.490 | Human |
| regulation of interferon gamma production | GO:0032649 | 36 | 0.488 | Human |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 28 | 0.484 | Human |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.483 | Human |
| actin filament bundle organization | GO:0061572 | 54 | 0.480 | Human Fly |
| positive regulation of interferon gamma mediated signaling pathway | GO:0060335 | 2 | 0.475 | Human |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.475 | |
| granulocyte migration | GO:0097530 | 40 | 0.474 | |
| positive regulation of locomotion | GO:0040017 | 186 | 0.472 | |
| cellular transition metal ion homeostasis | GO:0046916 | 21 | 0.471 | Human |
| positive regulation of peptide secretion | GO:0002793 | 15 | 0.468 | Human |
| response to cytokine | GO:0034097 | 232 | 0.459 | Human |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.456 | Fly |
| regulation of cellular component movement | GO:0051270 | 334 | 0.455 | Human |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.450 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.445 | |
| early endosome to late endosome transport | GO:0045022 | 21 | 0.444 | Human |
| regulation of hormone levels | GO:0010817 | 125 | 0.441 | Human |
| cellular response to interferon gamma | GO:0071346 | 24 | 0.441 | Human |
| cellular cation homeostasis | GO:0030003 | 163 | 0.440 | Human |
| taxis | GO:0042330 | 157 | 0.436 | Fly |
| regulation of mitochondrial membrane potential | GO:0051881 | 23 | 0.432 | Human |
| negative regulation of mitochondrial depolarization | GO:0051902 | 2 | 0.432 | Human |
| immune response | GO:0006955 | 307 | 0.429 | Human |
| secretion | GO:0046903 | 254 | 0.428 | Human |
| response to oxygen containing compound | GO:1901700 | 369 | 0.408 | Human |
| regulation of proteolysis | GO:0030162 | 293 | 0.407 | Human |
| tyrosine phosphorylation of stat5 protein | GO:0042506 | 13 | 0.407 | Human |
| regulation of kinase activity | GO:0043549 | 314 | 0.401 | Human Fly |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.399 | Human |
| hemopoiesis | GO:0030097 | 180 | 0.395 | Human |
| defense response to other organism | GO:0098542 | 129 | 0.388 | Mouse |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.388 | Human |
| regulation of leukocyte proliferation | GO:0070663 | 67 | 0.388 | |
| leukocyte migration | GO:0050900 | 107 | 0.385 | |
| response to interferon gamma | GO:0034341 | 39 | 0.385 | Human |
| positive regulation of hormone secretion | GO:0046887 | 25 | 0.384 | Human |
| membrane organization | GO:0061024 | 292 | 0.384 | |
| protein oligomerization | GO:0051259 | 173 | 0.383 | Human |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.381 | Human |
| response to lipid | GO:0033993 | 206 | 0.380 | Human |
| regulation of intracellular transport | GO:0032386 | 195 | 0.377 | Human |
| response to bacterium | GO:0009617 | 144 | 0.377 | Mouse |
| cellular zinc ion homeostasis | GO:0006882 | 10 | 0.376 | Human |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.375 | Human |
| positive regulation of leukocyte activation | GO:0002696 | 80 | 0.373 | Human |
| biological adhesion | GO:0022610 | 331 | 0.372 | Human Fly |
| stress fiber assembly | GO:0043149 | 40 | 0.371 | Human |
| cell adhesion | GO:0007155 | 325 | 0.370 | Human Fly |
| cellular homeostasis | GO:0019725 | 196 | 0.369 | Human |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.369 | |
| mapk cascade | GO:0000165 | 288 | 0.368 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.367 | Human |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.362 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.359 | Human |
| positive regulation of peptide hormone secretion | GO:0090277 | 15 | 0.358 | Human |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.358 | Human |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.357 | |
| peptide hormone secretion | GO:0030072 | 50 | 0.356 | Human |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.354 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.348 | Human |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.348 | Human |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.348 | |
| regulation of membrane depolarization | GO:0003254 | 19 | 0.345 | Human |
| regulation of cytokine mediated signaling pathway | GO:0001959 | 41 | 0.344 | Human |
| positive regulation of secretion | GO:0051047 | 116 | 0.340 | Human |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.339 | Human |
| mononuclear cell proliferation | GO:0032943 | 71 | 0.335 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.333 | |
| positive regulation of t cell proliferation | GO:0042102 | 33 | 0.332 | |
| positive regulation of leukocyte chemotaxis | GO:0002690 | 38 | 0.329 | |
| interferon gamma mediated signaling pathway | GO:0060333 | 7 | 0.326 | Human |
| system process | GO:0003008 | 349 | 0.326 | Fly |
| positive regulation of response to cytokine stimulus | GO:0060760 | 13 | 0.320 | Human |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.319 | |
| neurological system process | GO:0050877 | 163 | 0.318 | Fly |
| organ morphogenesis | GO:0009887 | 147 | 0.315 | Fly |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.315 | Human Fly |
| immune effector process | GO:0002252 | 159 | 0.314 | |
| regulation of immune response | GO:0050776 | 201 | 0.311 | Human |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.309 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.306 | Human |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.305 | |
| regulation of protein processing | GO:0070613 | 150 | 0.305 | Human |
| cell projection organization | GO:0030030 | 252 | 0.305 | Human Fly |
| regulation of ion homeostasis | GO:2000021 | 73 | 0.300 | Human |
| positive regulation of gtp catabolic process | GO:0033126 | 166 | 0.300 | |
| regulation of cell development | GO:0060284 | 161 | 0.300 | Human |
| cellular ion homeostasis | GO:0006873 | 168 | 0.298 | Human |
| regulation of lymphocyte proliferation | GO:0050670 | 64 | 0.295 | |
| plasma membrane organization | GO:0007009 | 115 | 0.294 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.291 | Human |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.291 | Human |
| regulation of peptidase activity | GO:0052547 | 180 | 0.290 | Human |
| negative regulation of cell death | GO:0060548 | 345 | 0.290 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.284 | Human |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.283 | Human |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.280 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.276 | Human Fly |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.276 | |
| protein kinase b signaling | GO:0043491 | 69 | 0.275 | Human |
| regulation of innate immune response | GO:0045088 | 97 | 0.273 | Human |
| negative regulation of protein oligomerization | GO:0032460 | 8 | 0.272 | Human |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.272 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.271 | Human |
| defense response to bacterium | GO:0042742 | 63 | 0.270 | Mouse |
| regulation of t cell activation | GO:0050863 | 77 | 0.270 | Human |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.269 | |
| regulation of peptide hormone secretion | GO:0090276 | 41 | 0.268 | Human |
| regulation of lipid kinase activity | GO:0043550 | 19 | 0.266 | Human |
| positive regulation of immune response | GO:0050778 | 159 | 0.265 | Human |
| endodermal cell fate commitment | GO:0001711 | 4 | 0.262 | |
| lymphocyte differentiation | GO:0030098 | 35 | 0.261 | Human |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.259 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.258 | Human |
| regulation of actin filament length | GO:0030832 | 56 | 0.256 | Fly |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.255 | |
| regulation of cytokine secretion | GO:0050707 | 57 | 0.255 | |
| regulation of protein secretion | GO:0050708 | 86 | 0.253 | |
| negative regulation of protein homooligomerization | GO:0032463 | 4 | 0.252 | Human |
| regulation of response to cytokine stimulus | GO:0060759 | 46 | 0.252 | Human |
| regulation of membrane potential | GO:0042391 | 95 | 0.249 | Human |
| regulation of cell activation | GO:0050865 | 125 | 0.248 | Human |
| positive regulation of lipid kinase activity | GO:0090218 | 13 | 0.245 | Human |
| positive regulation of rho gtpase activity | GO:0032321 | 56 | 0.245 | |
| protein processing | GO:0016485 | 226 | 0.243 | Human |
| organophosphate catabolic process | GO:0046434 | 430 | 0.243 | |
| protein maturation | GO:0051604 | 233 | 0.243 | Human |
| positive regulation of cell migration | GO:0030335 | 172 | 0.242 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 39 | 0.242 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.235 | Human |
| zymogen activation | GO:0031638 | 70 | 0.234 | Human |
| positive regulation of defense response | GO:0031349 | 87 | 0.233 | Human |
| nitrogen compound transport | GO:0071705 | 191 | 0.232 | Human |
| insulin secretion | GO:0030073 | 39 | 0.231 | Human |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.226 | Human |
| regulation of mononuclear cell proliferation | GO:0032944 | 65 | 0.223 | |
| azole transport | GO:0045117 | 4 | 0.223 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.221 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.219 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.211 | |
| lipid metabolic process | GO:0006629 | 381 | 0.210 | Human |
| positive regulation of transport | GO:0051050 | 336 | 0.210 | Human |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.199 | |
| salivary gland morphogenesis | GO:0007435 | 4 | 0.197 | Fly |
| cytokine secretion | GO:0050663 | 64 | 0.196 | |
| positive regulation of actin cytoskeleton reorganization | GO:2000251 | 9 | 0.196 | |
| generation of neurons | GO:0048699 | 152 | 0.196 | Human Fly |
| exocytosis | GO:0006887 | 71 | 0.195 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.195 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.193 | Human |
| mitotic cell cycle | GO:0000278 | 326 | 0.193 | |
| gtp metabolic process | GO:0046039 | 239 | 0.193 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.193 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.191 | Fly |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.190 | |
| phosphatidylinositol 3 kinase signaling | GO:0014065 | 48 | 0.190 | Human |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.189 | Human |
| innate immune response | GO:0045087 | 178 | 0.189 | Human |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.187 | Human |
| podosome assembly | GO:0071800 | 6 | 0.185 | |
| transition metal ion homeostasis | GO:0055076 | 31 | 0.185 | Human |
| response to growth factor | GO:0070848 | 205 | 0.181 | Human |
| g protein coupled receptor signaling pathway | GO:0007186 | 207 | 0.174 | |
| hepoxilin biosynthetic process | GO:0051122 | 1 | 0.172 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.170 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.168 | |
| positive regulation of insulin secretion | GO:0032024 | 10 | 0.167 | Human |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.165 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.165 | Human |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.162 | |
| positive regulation of protein complex assembly | GO:0031334 | 86 | 0.162 | |
| single organism membrane organization | GO:0044802 | 268 | 0.161 | |
| cell morphogenesis | GO:0000902 | 296 | 0.161 | |
| single organism cellular localization | GO:1902580 | 332 | 0.159 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 57 | 0.158 | Human |
| myoblast fusion | GO:0007520 | 1 | 0.158 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.155 | Human |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.155 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.155 | Fly |
| regulation of locomotion | GO:0040012 | 329 | 0.155 | Human |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 156 | 0.155 | |
| leukocyte proliferation | GO:0070661 | 74 | 0.154 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 46 | 0.154 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.153 | Human |
| cell activation involved in immune response | GO:0002263 | 30 | 0.153 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.152 | |
| positive regulation of lymphocyte activation | GO:0051251 | 73 | 0.152 | Human |
| regulation of phagocytosis | GO:0050764 | 21 | 0.150 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.149 | |
| ion homeostasis | GO:0050801 | 230 | 0.148 | Human |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 45 | 0.148 | Human |
| response to acid chemical | GO:0001101 | 66 | 0.146 | Human |
| digestive system development | GO:0055123 | 75 | 0.144 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.142 | |
| regulation of phosphatidylinositol 3 kinase signaling | GO:0014066 | 35 | 0.142 | Human |
| adaptive immune response | GO:0002250 | 49 | 0.141 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.141 | Human |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.140 | |
| heterotypic cell cell adhesion | GO:0034113 | 28 | 0.139 | |
| regulation of cell cell adhesion | GO:0022407 | 57 | 0.138 | Human |
| phospholipid metabolic process | GO:0006644 | 99 | 0.136 | Human |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.135 | |
| cation transport | GO:0006812 | 331 | 0.133 | |
| neuron projection development | GO:0031175 | 106 | 0.131 | Human Fly |
| intracellular protein transport | GO:0006886 | 270 | 0.130 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.129 | |
| cation homeostasis | GO:0055080 | 189 | 0.129 | Human |
| actomyosin structure organization | GO:0031032 | 59 | 0.128 | Human Fly |
| response to fungus | GO:0009620 | 4 | 0.127 | |
| osteoclast development | GO:0036035 | 2 | 0.127 | |
| cellular response to lipid | GO:0071396 | 127 | 0.127 | Human |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.127 | |
| regulation of endocytosis | GO:0030100 | 72 | 0.125 | |
| b cell receptor signaling pathway | GO:0050853 | 18 | 0.124 | Human |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.124 | Fly |
| positive regulation of vasoconstriction | GO:0045907 | 3 | 0.124 | |
| regulation of leukocyte chemotaxis | GO:0002688 | 46 | 0.123 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.123 | Human |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.122 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 38 | 0.122 | |
| leukocyte mediated immunity | GO:0002443 | 59 | 0.122 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.121 | |
| endosomal transport | GO:0016197 | 129 | 0.120 | Human |
| organelle assembly | GO:0070925 | 176 | 0.118 | |
| lymphocyte proliferation | GO:0046651 | 70 | 0.117 | |
| positive regulation of membrane protein ectodomain proteolysis | GO:0051044 | 13 | 0.117 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.116 | |
| tube development | GO:0035295 | 125 | 0.115 | |
| t cell proliferation | GO:0042098 | 45 | 0.113 | |
| mast cell degranulation | GO:0043303 | 4 | 0.113 | |
| regulation of protein tyrosine kinase activity | GO:0061097 | 36 | 0.113 | Human |
| endomembrane system organization | GO:0010256 | 196 | 0.113 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.113 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.112 | Human |
| granulocyte chemotaxis | GO:0071621 | 37 | 0.110 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.110 | |
| regulation of podosome assembly | GO:0071801 | 5 | 0.108 | |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.108 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.108 | Human Fly |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.108 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.108 | |
| female gamete generation | GO:0007292 | 2 | 0.107 | Fly |
| positive regulation of mononuclear cell proliferation | GO:0032946 | 47 | 0.107 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.107 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.106 | |
| activation of immune response | GO:0002253 | 114 | 0.106 | Human |
| inflammatory response | GO:0006954 | 79 | 0.104 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.104 | |
| digestive tract development | GO:0048565 | 75 | 0.104 | |
| mast cell activation involved in immune response | GO:0002279 | 4 | 0.103 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.102 | Human |
| regulation of cellular component size | GO:0032535 | 82 | 0.102 | Fly |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.101 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.100 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.100 | Human |
| regulation of peptide transport | GO:0090087 | 62 | 0.098 | Human |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.097 | Human |
| cell cell signaling | GO:0007267 | 155 | 0.097 | Human Fly |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.097 | Human |
| regulation of peptide secretion | GO:0002791 | 42 | 0.096 | Human |
| myeloid leukocyte differentiation | GO:0002573 | 60 | 0.096 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.095 | |
| epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway | GO:0035625 | 4 | 0.095 | |
| regulation of behavior | GO:0050795 | 82 | 0.094 | |
| regulation of response to interferon gamma | GO:0060330 | 7 | 0.094 | Human |
| negative regulation of protein complex assembly | GO:0031333 | 43 | 0.094 | Human |
| sensory perception of pain | GO:0019233 | 4 | 0.093 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.093 | |
| positive regulation of nervous system development | GO:0051962 | 54 | 0.092 | Human |
| regulation of immune effector process | GO:0002697 | 91 | 0.091 | |
| formation of primary germ layer | GO:0001704 | 42 | 0.091 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.090 | Human |
| regulation of neurogenesis | GO:0050767 | 82 | 0.090 | Human |
| receptor transactivation | GO:0035624 | 4 | 0.090 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.089 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.089 | |
| associative learning | GO:0008306 | 1 | 0.089 | Fly |
| regulation of mitochondrial depolarization | GO:0051900 | 6 | 0.088 | Human |
| cell substrate adhesion | GO:0031589 | 132 | 0.088 | |
| response to interleukin 1 | GO:0070555 | 47 | 0.088 | Human |
| cellular component morphogenesis | GO:0032989 | 314 | 0.088 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.087 | Human |
| membrane protein ectodomain proteolysis | GO:0006509 | 33 | 0.086 | |
| positive regulation of ras gtpase activity | GO:0032320 | 117 | 0.085 | |
| positive regulation of cellular component movement | GO:0051272 | 181 | 0.085 | |
| positive regulation of acute inflammatory response | GO:0002675 | 2 | 0.084 | |
| regulation of jak stat cascade | GO:0046425 | 44 | 0.084 | |
| erk1 and erk2 cascade | GO:0070371 | 104 | 0.083 | |
| positive regulation of actin filament polymerization | GO:0030838 | 38 | 0.083 | |
| syncytium formation by plasma membrane fusion | GO:0000768 | 2 | 0.083 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.082 | |
| growth | GO:0040007 | 202 | 0.082 | Fly |
| regulation of growth | GO:0040008 | 165 | 0.082 | Fly |
| oocyte development | GO:0048599 | 1 | 0.082 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.081 | |
| cellular response to retinoic acid | GO:0071300 | 19 | 0.080 | Human |
| leukocyte chemotaxis | GO:0030595 | 76 | 0.079 | |
| regulation of myeloid leukocyte mediated immunity | GO:0002886 | 4 | 0.079 | |
| positive regulation of response to external stimulus | GO:0032103 | 88 | 0.079 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 3 | 0.078 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.078 | Human |
| regulation of rho gtpase activity | GO:0032319 | 66 | 0.078 | |
| regulation of neuron differentiation | GO:0045664 | 70 | 0.077 | Human |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.077 | |
| tyrosine phosphorylation of stat protein | GO:0007260 | 33 | 0.077 | Human |
| phosphatidylinositol mediated signaling | GO:0048015 | 55 | 0.076 | Human |
| regulation of cell cycle | GO:0051726 | 393 | 0.075 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.074 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.074 | Human |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.074 | |
| lymphocyte mediated immunity | GO:0002449 | 48 | 0.073 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.073 | Human |
| epithelial cell cell adhesion | GO:0090136 | 7 | 0.073 | Fly |
| regulation of exocytosis | GO:0017157 | 46 | 0.073 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.073 | |
| positive regulation of neuron projection development | GO:0010976 | 34 | 0.073 | Human |
| positive regulation of behavior | GO:0048520 | 60 | 0.071 | |
| chemical homeostasis | GO:0048878 | 306 | 0.070 | Human |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.070 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.069 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.069 | Human Fly |
| negative regulation of dendritic cell differentiation | GO:2001199 | 2 | 0.068 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.067 | |
| signal release | GO:0023061 | 70 | 0.067 | Human |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.066 | Human |
| gtp catabolic process | GO:0006184 | 237 | 0.066 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.066 | Human |
| membrane protein proteolysis | GO:0033619 | 38 | 0.066 | |
| cell fate commitment involved in formation of primary germ layer | GO:0060795 | 6 | 0.066 | |
| leukocyte activation involved in immune response | GO:0002366 | 30 | 0.066 | |
| negative regulation of cellular component movement | GO:0051271 | 106 | 0.065 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.065 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.065 | Fly |
| nucleoside catabolic process | GO:0009164 | 408 | 0.065 | |
| positive regulation of chemotaxis | GO:0050921 | 57 | 0.064 | |
| regulation of cell shape | GO:0008360 | 48 | 0.064 | |
| regulation of neuron projection development | GO:0010975 | 57 | 0.064 | Human |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.064 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.064 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 40 | 0.062 | Human |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.061 | |
| inositol lipid mediated signaling | GO:0048017 | 55 | 0.061 | Human |
| t cell differentiation | GO:0030217 | 29 | 0.061 | Human |
| regulation of actin cytoskeleton reorganization | GO:2000249 | 12 | 0.060 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.060 | Fly |
| blood coagulation | GO:0007596 | 76 | 0.059 | |
| positive regulation of immune effector process | GO:0002699 | 40 | 0.059 | |
| wound healing | GO:0042060 | 115 | 0.059 | |
| regulation of epithelial cell migration | GO:0010632 | 93 | 0.058 | Human |
| neuron differentiation | GO:0030182 | 138 | 0.058 | Human Fly |
| negative regulation of nervous system development | GO:0051961 | 28 | 0.058 | Fly |
| metal ion transport | GO:0030001 | 272 | 0.058 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.057 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 48 | 0.056 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.056 | |
| protein secretion | GO:0009306 | 98 | 0.056 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 13 | 0.055 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.055 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.055 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.054 | |
| regulation of gamma delta t cell activation involved in immune response | GO:2001191 | 1 | 0.054 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.054 | |
| gland morphogenesis | GO:0022612 | 8 | 0.053 | Fly |
| rac protein signal transduction | GO:0016601 | 12 | 0.053 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.053 | |
| tube morphogenesis | GO:0035239 | 95 | 0.053 | |
| regulation of actin filament bundle assembly | GO:0032231 | 36 | 0.053 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.053 | Human |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.053 | |
| phagocytosis | GO:0006909 | 42 | 0.052 | |
| positive regulation of actin filament bundle assembly | GO:0032233 | 25 | 0.052 | |
| regulation of dendritic cell apoptotic process | GO:2000668 | 4 | 0.051 | |
| cell cell junction organization | GO:0045216 | 69 | 0.051 | Fly |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.051 | |
| positive regulation of protein secretion | GO:0050714 | 60 | 0.051 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.051 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.050 | Human |
| lipoxygenase pathway | GO:0019372 | 4 | 0.050 | |
| negative regulation of cytokine production | GO:0001818 | 82 | 0.050 | |
| renal system development | GO:0072001 | 63 | 0.050 | |
| cell cell junction assembly | GO:0007043 | 25 | 0.050 | Fly |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.050 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.049 | Human |
| mitotic cell cycle process | GO:1903047 | 286 | 0.049 | |
| regulation of receptor mediated endocytosis | GO:0048259 | 32 | 0.049 | Human |
| anoikis | GO:0043276 | 22 | 0.049 | Human |
