IMP: Integrative Multi-species Prediction

Homo sapiens

18 known processes

HNRPDL

heterogeneous nuclear ribonucleoprotein D-like

(Aliases: JKTBP2,JKTBP,laAUF1,HNRNP)

HGNC: 5037
MIM: 607137
Entrez: 9987
Ensembl: ENSG00000152795
HPRD: 06185
UniProtKB: O14979
UniProtKB: A0A024RDF6
UniProtKB: A0A087WUK2

Process Predictions
Disease Predictions

HNRPDL biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
female gamete generation	GO:0007292	2	0.961	Fly
rna splicing	GO:0008380	131	0.887	Fly
negative regulation of cell differentiation	GO:0045596	171	0.877
rna stabilization	GO:0043489	18	0.759
rna processing	GO:0006396	255	0.713	Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	89	0.686	Fly
post embryonic development	GO:0009791	2	0.587
translation	GO:0006412	132	0.437	Human
determination of adult lifespan	GO:0008340	2	0.427
chromatin organization	GO:0006325	351	0.390
regulation of rna splicing	GO:0043484	62	0.353	Fly
mitotic cell cycle process	GO:1903047	286	0.346
oogenesis	GO:0048477	2	0.331	Fly
stem cell differentiation	GO:0048863	93	0.314
mrna metabolic process	GO:0016071	175	0.308	Fly
organelle fission	GO:0048285	149	0.307
establishment of rna localization	GO:0051236	39	0.278
hemidesmosome assembly	GO:0031581	5	0.265
cytoplasmic transport	GO:0016482	379	0.252
stem cell development	GO:0048864	69	0.241
nucleobase containing compound transport	GO:0015931	51	0.240
oocyte development	GO:0048599	1	0.233	Fly
multicellular organismal aging	GO:0010259	3	0.226
growth	GO:0040007	202	0.205
embryo development	GO:0009790	123	0.202	Fly
nuclear division	GO:0000280	128	0.201
negative regulation of developmental process	GO:0051093	247	0.192
negative regulation of mrna splicing via spliceosome	GO:0048025	11	0.189
regulation of mrna splicing via spliceosome	GO:0048024	32	0.189	Fly
negative regulation of rna splicing	GO:0033119	15	0.179	Fly
mrna splicing via spliceosome	GO:0000398	89	0.172	Fly
alternative mrna splicing via spliceosome	GO:0000380	27	0.169	Fly
epithelium development	GO:0060429	227	0.159	Fly
defense response	GO:0006952	315	0.157
female gonad development	GO:0008585	10	0.143
cell development	GO:0048468	328	0.137	Fly
epithelial cell differentiation	GO:0030855	141	0.137	Fly
oocyte differentiation	GO:0009994	2	0.132	Fly
posttranscriptional regulation of gene expression	GO:0010608	213	0.129	Human
immune response	GO:0006955	307	0.126
nervous system development	GO:0007399	293	0.122
nuclear export	GO:0051168	69	0.117
negative regulation of mrna processing	GO:0050686	12	0.114
reproductive process	GO:0022414	106	0.113	Fly
mitotic nuclear division	GO:0007067	119	0.101
positive regulation of translation	GO:0045727	35	0.097	Human
cell junction assembly	GO:0034329	67	0.084
neuron differentiation	GO:0030182	138	0.083
single organism reproductive process	GO:0044702	98	0.081	Fly
nuclear transport	GO:0051169	179	0.078
mitotic cell cycle	GO:0000278	326	0.078
regulation of alternative mrna splicing via spliceosome	GO:0000381	22	0.077	Fly
spermatid development	GO:0007286	4	0.076
regulation of cell differentiation	GO:0045595	393	0.072
vesicle mediated transport	GO:0016192	371	0.070
positive regulation of developmental process	GO:0051094	314	0.070
embryo development ending in birth or egg hatching	GO:0009792	34	0.068
mrna stabilization	GO:0048255	18	0.066
ribonucleoprotein complex assembly	GO:0022618	78	0.065
nucleic acid transport	GO:0050657	39	0.064
response to abiotic stimulus	GO:0009628	336	0.064
stem cell division	GO:0017145	2	0.063
ribonucleoprotein complex biogenesis	GO:0022613	116	0.061
lipid localization	GO:0010876	106	0.058
gonad development	GO:0008406	34	0.056
regulation of translation	GO:0006417	89	0.055	Human
developmental process involved in reproduction	GO:0003006	66	0.054	Fly
cellular macromolecular complex assembly	GO:0034622	324	0.053
multi organism reproductive process	GO:0044703	54	0.049	Fly
response to biotic stimulus	GO:0009607	276	0.049
regulation of mrna metabolic process	GO:1903311	53	0.049	Fly
neurogenesis	GO:0022008	169	0.049
spermatid differentiation	GO:0048515	4	0.048
cell division	GO:0051301	168	0.047
reproductive structure development	GO:0048608	55	0.046
nuclear import	GO:0051170	106	0.045
osteoblast differentiation	GO:0001649	92	0.045
nitrogen compound transport	GO:0071705	191	0.044
regionalization	GO:0003002	29	0.044	Fly
regulation of cellular ketone metabolic process	GO:0010565	50	0.043
cellular macromolecule catabolic process	GO:0044265	380	0.043
spliceosomal complex assembly	GO:0000245	17	0.041
microtubule cytoskeleton organization	GO:0000226	176	0.041	Fly
rna transport	GO:0050658	39	0.041
regulation of cell cycle	GO:0051726	393	0.040
reproduction	GO:0000003	63	0.040	Fly
response to temperature stimulus	GO:0009266	22	0.039
regulation of meiosis	GO:0040020	3	0.039
pattern specification process	GO:0007389	43	0.038	Fly
cell substrate junction assembly	GO:0007044	35	0.036
organelle assembly	GO:0070925	176	0.035
ribonucleoprotein complex subunit organization	GO:0071826	81	0.035
generation of neurons	GO:0048699	152	0.034
stem cell maintenance	GO:0019827	19	0.034
negative regulation of cellular protein metabolic process	GO:0032269	353	0.034
cell growth	GO:0016049	160	0.033
nucleocytoplasmic transport	GO:0006913	176	0.032
positive regulation of cell death	GO:0010942	263	0.032
mrna processing	GO:0006397	133	0.031	Fly
regulation of growth	GO:0040008	165	0.030
cell morphogenesis	GO:0000902	296	0.030
cell junction organization	GO:0034330	79	0.030
multicellular organism reproduction	GO:0032504	42	0.029	Fly
immune system development	GO:0002520	195	0.029
rna localization	GO:0006403	41	0.029	Fly
reproductive system development	GO:0061458	56	0.029
sex differentiation	GO:0007548	45	0.029
protein stabilization	GO:0050821	64	0.028
regulation of rna stability	GO:0043487	23	0.028
response to heat	GO:0009408	21	0.027
positive regulation of growth	GO:0045927	58	0.027
ossification	GO:0001503	121	0.027
negative regulation of mrna metabolic process	GO:1903312	15	0.025
response to starvation	GO:0042594	59	0.024
response to lipid	GO:0033993	206	0.024
locomotory behavior	GO:0007626	1	0.024
response to other organism	GO:0051707	261	0.024
amine metabolic process	GO:0009308	44	0.024
transmembrane transport	GO:0055085	399	0.023
regulation of cellular response to stress	GO:0080135	244	0.023
response to oxygen containing compound	GO:1901700	369	0.023
regulation of meiotic cell cycle	GO:0051445	4	0.022
positive regulation of cell proliferation	GO:0008284	301	0.022
aging	GO:0007568	66	0.021
negative regulation of cell death	GO:0060548	345	0.021
negative regulation of phosphorus metabolic process	GO:0010563	267	0.020
negative regulation of protein metabolic process	GO:0051248	391	0.020
development of primary sexual characteristics	GO:0045137	35	0.020
response to lipopolysaccharide	GO:0032496	70	0.020
axon extension	GO:0048675	13	0.019
regulation of protein stability	GO:0031647	87	0.019
peptidyl lysine modification	GO:0018205	144	0.019
ribosome biogenesis	GO:0042254	48	0.019
maintenance of location	GO:0051235	112	0.019
taxis	GO:0042330	157	0.019
multicellular organismal reproductive process	GO:0048609	40	0.018	Fly
regulation of cellular amino acid metabolic process	GO:0006521	6	0.018
protein processing	GO:0016485	226	0.018
cellular component morphogenesis	GO:0032989	314	0.018
regulation of cell cycle process	GO:0010564	266	0.018
response to fungus	GO:0009620	4	0.017
regulation of endopeptidase activity	GO:0052548	170	0.017
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	281	0.017
negative regulation of apoptotic process	GO:0043066	316	0.017
chemotaxis	GO:0006935	157	0.017
regulation of mrna stability	GO:0043488	23	0.017
developmental cell growth	GO:0048588	18	0.016
cellular amine metabolic process	GO:0044106	41	0.016
neuron projection extension involved in neuron projection guidance	GO:1902284	5	0.016
negative regulation of cellular component organization	GO:0051129	235	0.016
gamete generation	GO:0007276	25	0.016	Fly
neuromuscular junction development	GO:0007528	3	0.015
response to wounding	GO:0009611	168	0.015
response to external biotic stimulus	GO:0043207	261	0.015
cellular ketone metabolic process	GO:0042180	80	0.015
receptor mediated endocytosis	GO:0006898	84	0.015
tissue regeneration	GO:0042246	3	0.015
regulation of response to wounding	GO:1903034	101	0.015
response to bacterium	GO:0009617	144	0.015
rna splicing via transesterification reactions	GO:0000375	90	0.014	Fly
cellular response to cytokine stimulus	GO:0071345	181	0.014
cell morphogenesis involved in differentiation	GO:0000904	144	0.014
protein dna complex subunit organization	GO:0071824	80	0.014
negative regulation of cell cycle phase transition	GO:1901988	89	0.014
response to nutrient levels	GO:0031667	81	0.014
regulation of cell growth	GO:0001558	135	0.014
actin cytoskeleton organization	GO:0030036	207	0.013
regulation of mapk cascade	GO:0043408	262	0.013
muscle structure development	GO:0061061	98	0.013
negative regulation of hydrolase activity	GO:0051346	182	0.013
regeneration	GO:0031099	4	0.013
dorsal ventral pattern formation	GO:0009953	15	0.013	Fly
cell activation	GO:0001775	213	0.013
epithelial cell proliferation	GO:0050673	128	0.013
regulation of cysteine type endopeptidase activity	GO:2000116	127	0.013
segmentation	GO:0035282	4	0.012	Fly
cell projection organization	GO:0030030	252	0.012
regulation of mrna processing	GO:0050684	48	0.012	Fly
positive regulation of protein complex assembly	GO:0031334	86	0.012
myeloid cell differentiation	GO:0030099	117	0.012
cellular response to oxygen containing compound	GO:1901701	276	0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	116	0.012
regulation of growth rate	GO:0040009	1	0.012
sexual reproduction	GO:0019953	37	0.012	Fly
rna interference	GO:0016246	4	0.012
axis specification	GO:0009798	12	0.012	Fly
skeletal muscle tissue growth	GO:0048630	2	0.012
negative regulation of catalytic activity	GO:0043086	335	0.012
cellular amino acid metabolic process	GO:0006520	116	0.012
actin filament based process	GO:0030029	224	0.011
positive regulation of transport	GO:0051050	336	0.011
nucleosome organization	GO:0034728	66	0.011
female sex differentiation	GO:0046660	12	0.011
organ morphogenesis	GO:0009887	147	0.011
spermatogenesis	GO:0007283	22	0.011
response to extracellular stimulus	GO:0009991	85	0.011
developmental growth	GO:0048589	48	0.011
chemical homeostasis	GO:0048878	306	0.011
innate immune response	GO:0045087	178	0.010
positive regulation of cellular amine metabolic process	GO:0033240	7	0.010
regulation of leukocyte activation	GO:0002694	115	0.010
multi organism cellular process	GO:0044764	156	0.010
cell type specific apoptotic process	GO:0097285	125	0.010
regulation of lymphocyte activation	GO:0051249	103	0.010
endocytosis	GO:0006897	159	0.010
regulation of response to external stimulus	GO:0032101	222	0.010
neuron development	GO:0048666	113	0.010

HNRPDL disease predictions

Disease	DO term ID	Size	Probability
central nervous system disease	DOID:331	186	0.085
nervous system disease	DOID:863	431	0.085
neurodegenerative disease	DOID:1289	102	0.032
musculoskeletal system disease	DOID:17	223	0.008
myopathy	DOID:423	104	0.004
muscular disease	DOID:0080000	114	0.004
muscular dystrophy	DOID:9884	51	0.004
muscle tissue disease	DOID:66	113	0.004
limb girdle muscular dystrophy	DOID:11724	25	0.000

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