| mitochondrion organization | GO:0007005 | 156 | 0.832 | |
| post embryonic development | GO:0009791 | 2 | 0.754 | Worm Fly |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.383 | Fly |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.383 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.380 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.332 | |
| immune response | GO:0006955 | 307 | 0.321 | |
| lipid metabolic process | GO:0006629 | 381 | 0.317 | Human Fly |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.281 | Fly |
| oxidation reduction process | GO:0055114 | 396 | 0.244 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.215 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.197 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.167 | |
| protein processing | GO:0016485 | 226 | 0.158 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.157 | |
| protein localization to organelle | GO:0033365 | 280 | 0.154 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.151 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.149 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.147 | |
| growth | GO:0040007 | 202 | 0.135 | |
| endocytosis | GO:0006897 | 159 | 0.133 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.127 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.124 | |
| membrane organization | GO:0061024 | 292 | 0.124 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 186 | 0.121 | |
| regulation of growth | GO:0040008 | 165 | 0.119 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.116 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.115 | |
| cell development | GO:0048468 | 328 | 0.109 | |
| female gamete generation | GO:0007292 | 2 | 0.109 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.105 | |
| single organism membrane organization | GO:0044802 | 268 | 0.104 | |
| mitochondrial transport | GO:0006839 | 60 | 0.103 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.097 | |
| cofactor metabolic process | GO:0051186 | 87 | 0.090 | Fly |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.089 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.089 | |
| protein maturation | GO:0051604 | 233 | 0.088 | |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.086 | |
| atp metabolic process | GO:0046034 | 176 | 0.082 | |
| locomotory behavior | GO:0007626 | 1 | 0.081 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.078 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.077 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.077 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.073 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.072 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.070 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.069 | |
| regulation of immune response | GO:0050776 | 201 | 0.069 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.069 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.068 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.067 | |
| oogenesis | GO:0048477 | 2 | 0.065 | |
| intracellular protein transport | GO:0006886 | 270 | 0.063 | |
| behavior | GO:0007610 | 112 | 0.062 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.062 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 71 | 0.060 | |
| mitochondrial membrane organization | GO:0007006 | 40 | 0.060 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.059 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.059 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.058 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.057 | |
| protein catabolic process | GO:0030163 | 325 | 0.055 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.054 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.054 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.051 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.051 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.051 | |
| fatty acid metabolic process | GO:0006631 | 115 | 0.050 | Fly |
| amine metabolic process | GO:0009308 | 44 | 0.050 | |
| defense response | GO:0006952 | 315 | 0.049 | |
| mitochondrial atp synthesis coupled electron transport | GO:0042775 | 4 | 0.047 | |
| immune effector process | GO:0002252 | 159 | 0.047 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.047 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.046 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.046 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.045 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.044 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 187 | 0.044 | |
| embryo development | GO:0009790 | 123 | 0.044 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.043 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.043 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.043 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.043 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.042 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.041 | |
| negative regulation of transport | GO:0051051 | 176 | 0.041 | |
| organic hydroxy compound metabolic process | GO:1901615 | 147 | 0.040 | Fly |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.040 | |
| regulation of defense response | GO:0031347 | 154 | 0.040 | |
| cellular homeostasis | GO:0019725 | 196 | 0.040 | |
| biological adhesion | GO:0022610 | 331 | 0.040 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.039 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.039 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.038 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.038 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.037 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.036 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.036 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.036 | |
| response to oxidative stress | GO:0006979 | 121 | 0.035 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.035 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.035 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.035 | |
| small molecule catabolic process | GO:0044282 | 92 | 0.034 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.034 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.033 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.033 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.033 | |
| regulation of protein localization | GO:0032880 | 296 | 0.032 | |
| single organism cellular localization | GO:1902580 | 332 | 0.032 | |
| positive regulation of transport | GO:0051050 | 336 | 0.031 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.031 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.031 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.031 | |
| ion homeostasis | GO:0050801 | 230 | 0.030 | |
| mitochondrial calcium ion homeostasis | GO:0051560 | 11 | 0.030 | |
| aging | GO:0007568 | 66 | 0.030 | Rat |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.030 | |
| nucleotide biosynthetic process | GO:0009165 | 109 | 0.030 | |
| response to lipid | GO:0033993 | 206 | 0.030 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.029 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.029 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.028 | |
| protein localization to membrane | GO:0072657 | 160 | 0.028 | |
| protein import into mitochondrial inner membrane | GO:0045039 | 3 | 0.028 | |
| protein targeting | GO:0006605 | 187 | 0.027 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.027 | |
| cytokine production | GO:0001816 | 247 | 0.027 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.027 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.027 | |
| cellular response to lipid | GO:0071396 | 127 | 0.027 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.026 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.026 | |
| secretion | GO:0046903 | 254 | 0.026 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.026 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.026 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.026 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.026 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.025 | |
| protein localization to mitochondrion | GO:0070585 | 25 | 0.025 | |
| reproductive system development | GO:0061458 | 56 | 0.025 | Rat Worm |
| cellular cation homeostasis | GO:0030003 | 163 | 0.025 | |
| inner mitochondrial membrane organization | GO:0007007 | 8 | 0.025 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.025 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.025 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.024 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.024 | |
| protein oligomerization | GO:0051259 | 173 | 0.024 | Rat |
| negative regulation of growth | GO:0045926 | 97 | 0.024 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.024 | |
| t cell activation | GO:0042110 | 99 | 0.024 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.023 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.023 | |
| regulation of protein processing | GO:0070613 | 150 | 0.023 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.023 | |
| chemical homeostasis | GO:0048878 | 306 | 0.023 | |
| innate immune response | GO:0045087 | 178 | 0.023 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.023 | |
| dna replication | GO:0006260 | 116 | 0.022 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.022 | |
| regulation of transmembrane transporter activity | GO:0022898 | 74 | 0.022 | |
| system process | GO:0003008 | 349 | 0.021 | |
| secretion by cell | GO:0032940 | 226 | 0.021 | |
| sex differentiation | GO:0007548 | 45 | 0.021 | Rat Worm |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.021 | |
| response to cytokine | GO:0034097 | 232 | 0.021 | |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.021 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.021 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.021 | |
| regulation of cell development | GO:0060284 | 161 | 0.021 | |
| regulation of secretion | GO:0051046 | 194 | 0.020 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.020 | Rat Worm |
| nitrogen compound transport | GO:0071705 | 191 | 0.020 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.020 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.020 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.020 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.019 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.019 | |
| reproduction | GO:0000003 | 63 | 0.019 | Worm |
| cation homeostasis | GO:0055080 | 189 | 0.019 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.018 | |
| regulation of mitochondrial membrane potential | GO:0051881 | 23 | 0.018 | |
| response to other organism | GO:0051707 | 261 | 0.018 | |
| cardiovascular system development | GO:0072358 | 262 | 0.018 | |
| single organism reproductive process | GO:0044702 | 98 | 0.018 | Rat Worm |
| protein import | GO:0017038 | 130 | 0.018 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.018 | |
| phospholipid metabolic process | GO:0006644 | 99 | 0.018 | |
| mrna metabolic process | GO:0016071 | 175 | 0.018 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.017 | |
| transmembrane transport | GO:0055085 | 399 | 0.017 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.017 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.017 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.017 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.017 | |
| cell activation | GO:0001775 | 213 | 0.017 | |
| regulation of protein targeting | GO:1903533 | 91 | 0.017 | |
| nervous system development | GO:0007399 | 293 | 0.017 | |
| cell adhesion | GO:0007155 | 325 | 0.017 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.017 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.016 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.016 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.016 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.016 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.016 | |
| ribonucleotide biosynthetic process | GO:0009260 | 81 | 0.016 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.015 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.015 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.015 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.015 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.015 | |
| leukocyte activation | GO:0045321 | 164 | 0.015 | |
| response to bacterium | GO:0009617 | 144 | 0.015 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.015 | |
| positive regulation of gtpase activity | GO:0043547 | 166 | 0.015 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.015 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.015 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.015 | |
| response to acid chemical | GO:0001101 | 66 | 0.015 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.015 | |
| response to hormone | GO:0009725 | 175 | 0.015 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.015 | |
| epithelial cell proliferation | GO:0050673 | 128 | 0.014 | |
| activation of immune response | GO:0002253 | 114 | 0.014 | |
| gtp catabolic process | GO:0006184 | 237 | 0.014 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.014 | |
| regulation of mitochondrion organization | GO:0010821 | 54 | 0.014 | |
| rna interference | GO:0016246 | 4 | 0.014 | |
| gtp metabolic process | GO:0046039 | 239 | 0.014 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 79 | 0.013 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.013 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.013 | Fly |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.013 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.013 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.013 | |
| regulation of multicellular organism growth | GO:0040014 | 8 | 0.013 | |
| cellular response to acid chemical | GO:0071229 | 44 | 0.013 | |
| ribose phosphate biosynthetic process | GO:0046390 | 82 | 0.013 | |
| microtubule based process | GO:0007017 | 210 | 0.013 | |
| microtubule cytoskeleton organization | GO:0000226 | 176 | 0.013 | |
| gene silencing | GO:0016458 | 49 | 0.013 | |
| establishment of protein localization to membrane | GO:0090150 | 121 | 0.013 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.013 | |
| protein acetylation | GO:0006473 | 116 | 0.013 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.013 | |
| regulation of cell growth | GO:0001558 | 135 | 0.013 | |
| actin filament based process | GO:0030029 | 224 | 0.013 | |
| osteoblast differentiation | GO:0001649 | 92 | 0.012 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.012 | |
| gonad development | GO:0008406 | 34 | 0.012 | Rat Worm |
| regulation of gtpase activity | GO:0043087 | 180 | 0.012 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.012 | |
| organophosphate biosynthetic process | GO:0090407 | 163 | 0.012 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.012 | |
| regulation of gene expression epigenetic | GO:0040029 | 73 | 0.012 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.012 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 102 | 0.012 | |
| cell type specific apoptotic process | GO:0097285 | 125 | 0.012 | |
| organic acid biosynthetic process | GO:0016053 | 97 | 0.012 | |
| regulation of binding | GO:0051098 | 111 | 0.012 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.011 | |
| developmental growth | GO:0048589 | 48 | 0.011 | |
| cell growth | GO:0016049 | 160 | 0.011 | |
| chromatin organization | GO:0006325 | 351 | 0.011 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.011 | |
| lymphocyte activation | GO:0046649 | 133 | 0.011 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.011 | |
| regulation of inflammatory response | GO:0050727 | 46 | 0.011 | |
| glycerophospholipid metabolic process | GO:0006650 | 84 | 0.011 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.011 | |
| hemopoiesis | GO:0030097 | 180 | 0.011 | |
| mitochondrion morphogenesis | GO:0070584 | 8 | 0.011 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.011 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.011 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.011 | |
| positive regulation of lipid metabolic process | GO:0045834 | 50 | 0.011 | |
| dna repair | GO:0006281 | 198 | 0.011 | |
| protein acylation | GO:0043543 | 138 | 0.010 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.010 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.010 | |
| chromatin modification | GO:0016568 | 298 | 0.010 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.010 | |
