| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 1.000 | Human |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 1.000 | Human |
| detection of muramyl dipeptide | GO:0032498 | 1 | 1.000 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 1.000 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 1.000 | Human Mouse |
| response to molecule of bacterial origin | GO:0002237 | 82 | 0.999 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.999 | Fly |
| positive regulation of defense response | GO:0031349 | 87 | 0.997 | Fly |
| defense response to virus | GO:0051607 | 71 | 0.997 | Fly |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.996 | |
| serine phosphorylation of stat protein | GO:0042501 | 4 | 0.995 | |
| cytokine mediated signaling pathway | GO:0019221 | 109 | 0.994 | |
| regulation of interferon beta production | GO:0032648 | 22 | 0.994 | Human |
| i kappab phosphorylation | GO:0007252 | 7 | 0.992 | Mouse |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.991 | |
| innate immune response | GO:0045087 | 178 | 0.990 | Fly |
| response to virus | GO:0009615 | 126 | 0.990 | Fly |
| regulation of cytokine production | GO:0001817 | 232 | 0.990 | Human |
| mapk cascade | GO:0000165 | 288 | 0.988 | |
| regulation of immune response | GO:0050776 | 201 | 0.987 | Fly |
| amide biosynthetic process | GO:0043604 | 15 | 0.986 | Fly |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.985 | Human |
| defense response to bacterium | GO:0042742 | 63 | 0.985 | Fly |
| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 4 | 0.985 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 62 | 0.984 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.984 | Human |
| response to cytokine | GO:0034097 | 232 | 0.982 | |
| response to lipid | GO:0033993 | 206 | 0.980 | Rat |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.980 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.979 | |
| innate immune response activating signal transduction | GO:0002758 | 48 | 0.976 | |
| activation of jnkk activity | GO:0007256 | 1 | 0.976 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.972 | |
| nik nf kappab signaling | GO:0038061 | 12 | 0.972 | Human |
| regulation of stress activated mapk cascade | GO:0032872 | 84 | 0.968 | |
| positive regulation of humoral immune response | GO:0002922 | 3 | 0.966 | Fly |
| defense response | GO:0006952 | 315 | 0.966 | Fly |
| activation of innate immune response | GO:0002218 | 55 | 0.964 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.960 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 39 | 0.959 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.958 | |
| regulation of innate immune response | GO:0045088 | 97 | 0.950 | Fly |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.948 | Human |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.947 | Human |
| regulation of antimicrobial humoral response | GO:0002759 | 1 | 0.937 | Fly |
| regulation of defense response to virus by host | GO:0050691 | 22 | 0.935 | Fly |
| cellular response to nitrogen compound | GO:1901699 | 144 | 0.935 | |
| regulation of defense response | GO:0031347 | 154 | 0.933 | Fly |
| response to biotic stimulus | GO:0009607 | 276 | 0.931 | Fly |
| response to oxygen containing compound | GO:1901700 | 369 | 0.928 | Rat |
| response to external biotic stimulus | GO:0043207 | 261 | 0.926 | Fly |
| cardiovascular system development | GO:0072358 | 262 | 0.926 | |
| response to bacterium | GO:0009617 | 144 | 0.924 | Fly |
| cytoplasmic pattern recognition receptor signaling pathway | GO:0002753 | 12 | 0.923 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.923 | |
| intracellular protein transport | GO:0006886 | 270 | 0.921 | |
| oogenesis | GO:0048477 | 2 | 0.915 | |
| positive regulation of mapk cascade | GO:0043410 | 190 | 0.912 | |
| positive regulation of mhc class i biosynthetic process | GO:0045345 | 4 | 0.912 | |
| positive regulation of interferon alpha production | GO:0032727 | 11 | 0.911 | Human |
| pattern recognition receptor signaling pathway | GO:0002221 | 48 | 0.911 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 89 | 0.910 | |
| regulation of mapk cascade | GO:0043408 | 262 | 0.910 | |
| intracellular receptor signaling pathway | GO:0030522 | 104 | 0.905 | |
| regulation of defense response to virus | GO:0050688 | 33 | 0.903 | Fly |
| myeloid cell differentiation | GO:0030099 | 117 | 0.902 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.897 | |
| immune response activating signal transduction | GO:0002757 | 90 | 0.894 | |
| positive regulation of innate immune response | GO:0045089 | 79 | 0.894 | |
| metal ion transport | GO:0030001 | 272 | 0.881 | Mouse |
| positive regulation of interleukin 1 beta secretion | GO:0050718 | 11 | 0.871 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 11 | 0.869 | Fly |
| cellular response to peptide | GO:1901653 | 59 | 0.868 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.867 | |
| signal transduction by phosphorylation | GO:0023014 | 297 | 0.863 | Human |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.859 | |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.859 | Fly |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.853 | |
| cellular response to tumor necrosis factor | GO:0071356 | 63 | 0.852 | |
| regulation of immune effector process | GO:0002697 | 91 | 0.847 | Fly |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.844 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.836 | |
| response to other organism | GO:0051707 | 261 | 0.833 | Fly |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.828 | Fly |
| regulation of protein targeting | GO:1903533 | 91 | 0.828 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.826 | |
| response to peptide | GO:1901652 | 65 | 0.824 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.819 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.817 | Fly |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.814 | |
| defense response to other organism | GO:0098542 | 129 | 0.811 | Fly |
| regulation of multi organism process | GO:0043900 | 157 | 0.809 | Fly |
| protein targeting to nucleus | GO:0044744 | 104 | 0.799 | |
| response to fungus | GO:0009620 | 4 | 0.799 | |
| cytokine production | GO:0001816 | 247 | 0.798 | Human |
| positive regulation of jnk cascade | GO:0046330 | 52 | 0.795 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.795 | |
| immune response | GO:0006955 | 307 | 0.783 | Fly |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.781 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.779 | Rat |
| regulation of type i interferon mediated signaling pathway | GO:0060338 | 9 | 0.776 | |
| positive regulation of transport | GO:0051050 | 336 | 0.776 | Mouse |
| response to nitrogen compound | GO:1901698 | 184 | 0.775 | |
| negative regulation of cytokine production | GO:0001818 | 82 | 0.774 | |
| regulation of defense response to bacterium | GO:1900424 | 2 | 0.769 | Fly |
| single organism nuclear import | GO:1902593 | 104 | 0.768 | |
| negative regulation of protein transport | GO:0051224 | 75 | 0.766 | |
| positive regulation of defense response to virus by host | GO:0002230 | 14 | 0.765 | Fly |
| positive regulation of antimicrobial humoral response | GO:0002760 | 1 | 0.764 | Fly |
| nf kappab import into nucleus | GO:0042348 | 22 | 0.752 | |
| cytokine biosynthetic process | GO:0042089 | 37 | 0.748 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.748 | |
| negative regulation of immune system process | GO:0002683 | 136 | 0.726 | |
| lipid transport | GO:0006869 | 90 | 0.724 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.722 | |
| nuclear transport | GO:0051169 | 179 | 0.721 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.721 | |
| translation | GO:0006412 | 132 | 0.718 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.718 | |
| transcription factor import into nucleus | GO:0042991 | 40 | 0.716 | |
| positive regulation of interleukin 1 beta production | GO:0032731 | 13 | 0.716 | |
| positive regulation of response to external stimulus | GO:0032103 | 88 | 0.716 | Fly |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 4 | 0.708 | |
| immune response regulating signaling pathway | GO:0002764 | 97 | 0.704 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.698 | |
| tube development | GO:0035295 | 125 | 0.693 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.682 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.682 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.679 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.676 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 51 | 0.667 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.664 | |
| activation of immune response | GO:0002253 | 114 | 0.662 | |
| response to tumor necrosis factor | GO:0034612 | 76 | 0.647 | |
| interleukin 1 production | GO:0032612 | 26 | 0.644 | |
| cellular response to lipid | GO:0071396 | 127 | 0.640 | |
| cellular response to biotic stimulus | GO:0071216 | 71 | 0.636 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.635 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 35 | 0.628 | |
| regulation of interferon alpha production | GO:0032647 | 11 | 0.626 | Human |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.618 | |
| osteoclast differentiation | GO:0030316 | 21 | 0.617 | |
| segmentation | GO:0035282 | 4 | 0.616 | |
| regulation of response to biotic stimulus | GO:0002831 | 55 | 0.609 | Fly |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.606 | |
| cell development | GO:0048468 | 328 | 0.606 | Rat |
| regulation of type i interferon production | GO:0032479 | 26 | 0.600 | Human |
| cellular amide metabolic process | GO:0043603 | 69 | 0.597 | Fly |
| regulation of tumor necrosis factor production | GO:0032680 | 43 | 0.596 | |
| regulation of interleukin 1 beta secretion | GO:0050706 | 12 | 0.594 | |
| epiboly involved in gastrulation with mouth forming second | GO:0055113 | 1 | 0.593 | |
| negative regulation of i kappab kinase nf kappab signaling | GO:0043124 | 32 | 0.589 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.584 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.583 | |
| release of cytoplasmic sequestered nf kappab | GO:0008588 | 4 | 0.582 | |
| protein import | GO:0017038 | 130 | 0.579 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.572 | |
| protein catabolic process | GO:0030163 | 325 | 0.567 | Fly |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.564 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.561 | |
| response to peptide hormone | GO:0043434 | 61 | 0.558 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.554 | Fly |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.552 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.546 | |
| cellular response to interferon gamma | GO:0071346 | 24 | 0.537 | |
| tumor necrosis factor production | GO:0032640 | 43 | 0.534 | |
| activation of protein kinase activity | GO:0032147 | 90 | 0.534 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 44 | 0.527 | |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 26 | 0.526 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 98 | 0.524 | |
| interleukin 1 beta production | GO:0032611 | 22 | 0.524 | |
| regulation of autophagy | GO:0010506 | 52 | 0.514 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 50 | 0.510 | Human |
| tube morphogenesis | GO:0035239 | 95 | 0.494 | |
| cellular response to lipopolysaccharide | GO:0071222 | 57 | 0.494 | |
| antifungal humoral response | GO:0019732 | 2 | 0.490 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 284 | 0.481 | |
| interferon beta production | GO:0032608 | 23 | 0.481 | Human |
| positive regulation of tumor necrosis factor superfamily cytokine production | GO:1903557 | 22 | 0.478 | |
| regulation of protein localization | GO:0032880 | 296 | 0.472 | |
| immune effector process | GO:0002252 | 159 | 0.461 | Fly |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.459 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.454 | |
| type i interferon signaling pathway | GO:0060337 | 11 | 0.452 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 9 | 0.450 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.447 | |
| negative regulation of lipid storage | GO:0010888 | 11 | 0.438 | |
| fat soluble vitamin metabolic process | GO:0006775 | 19 | 0.430 | |
| dephosphorylation | GO:0016311 | 209 | 0.423 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.422 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.420 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.420 | |
| production of molecular mediator of immune response | GO:0002440 | 37 | 0.412 | Fly |
| somitogenesis | GO:0001756 | 2 | 0.412 | |
| regulation of protein transport | GO:0051223 | 213 | 0.405 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.404 | |
| nervous system development | GO:0007399 | 293 | 0.404 | Rat |
| protein import into nucleus translocation | GO:0000060 | 22 | 0.399 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.390 | |
| organic hydroxy compound transport | GO:0015850 | 63 | 0.388 | |
| interleukin 6 production | GO:0032635 | 37 | 0.384 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.383 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 46 | 0.381 | |
| cellular response to mechanical stimulus | GO:0071260 | 39 | 0.379 | |
| regulation of jak stat cascade | GO:0046425 | 44 | 0.374 | |
| detection of peptidoglycan | GO:0032499 | 1 | 0.373 | |
| positive regulation of protein import into nucleus | GO:0042307 | 46 | 0.370 | |
| cholesterol transport | GO:0030301 | 39 | 0.370 | |
| negative regulation of intracellular protein transport | GO:0090317 | 42 | 0.370 | |
| angiogenesis | GO:0001525 | 147 | 0.367 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.365 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.363 | |
| secretion | GO:0046903 | 254 | 0.355 | |
| system process | GO:0003008 | 349 | 0.353 | Rat |
| vitamin d metabolic process | GO:0042359 | 10 | 0.350 | |
| female gamete generation | GO:0007292 | 2 | 0.348 | |
| type i interferon production | GO:0032606 | 27 | 0.348 | Human |
| multicellular organismal aging | GO:0010259 | 3 | 0.340 | |
| regulation of interleukin 6 production | GO:0032675 | 37 | 0.337 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 45 | 0.337 | |
| interleukin 1 beta secretion | GO:0050702 | 15 | 0.335 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.334 | |
| cation transport | GO:0006812 | 331 | 0.334 | Mouse |
| regulation of intracellular protein transport | GO:0033157 | 123 | 0.333 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.333 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.332 | |
| cell morphogenesis | GO:0000902 | 296 | 0.332 | |
| protein localization to organelle | GO:0033365 | 280 | 0.323 | |
| protein targeting | GO:0006605 | 187 | 0.317 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.313 | |
| lactation | GO:0007595 | 3 | 0.313 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 37 | 0.312 | |
| regulation of mhc class i biosynthetic process | GO:0045343 | 4 | 0.304 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.296 | |
| peptide transport | GO:0015833 | 74 | 0.294 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.291 | |
| intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator | GO:0042771 | 23 | 0.289 | |
| regulation of interleukin 8 production | GO:0032677 | 49 | 0.285 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.281 | |
| negative regulation of interleukin 1 secretion | GO:0050711 | 4 | 0.279 | |
| n terminal protein amino acid modification | GO:0031365 | 13 | 0.274 | |
| embryonic morphogenesis | GO:0048598 | 85 | 0.270 | |
| regulation of protein import into nucleus | GO:0042306 | 78 | 0.269 | |
| negative regulation of protein import into nucleus | GO:0042308 | 30 | 0.268 | |
| maintenance of location | GO:0051235 | 112 | 0.267 | |
| neural tube formation | GO:0001841 | 3 | 0.267 | |
| protein ubiquitination | GO:0016567 | 314 | 0.265 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.262 | |
| sterol transport | GO:0015918 | 39 | 0.260 | |
| interleukin 1 secretion | GO:0050701 | 18 | 0.259 | |
| negative regulation of macrophage derived foam cell differentiation | GO:0010745 | 7 | 0.258 | |
| negative regulation of intracellular transport | GO:0032387 | 60 | 0.255 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 60 | 0.254 | |
| morphogenesis of an epithelium | GO:0002009 | 60 | 0.254 | |
| negative regulation of transport | GO:0051051 | 176 | 0.253 | |
| regulation of translation | GO:0006417 | 89 | 0.248 | |
| regulation of nf kappab import into nucleus | GO:0042345 | 22 | 0.245 | |
| lipid metabolic process | GO:0006629 | 381 | 0.245 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.242 | |
| leukocyte activation | GO:0045321 | 164 | 0.238 | |
| hemopoiesis | GO:0030097 | 180 | 0.235 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.232 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.230 | |
| somatic muscle development | GO:0007525 | 1 | 0.230 | |
| positive regulation of peptidase activity | GO:0010952 | 88 | 0.229 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.227 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.226 | |
| immune system development | GO:0002520 | 195 | 0.224 | |
| positive regulation of type i interferon production | GO:0032481 | 20 | 0.223 | Human |
| negative regulation of protein localization to nucleus | GO:1900181 | 34 | 0.223 | |
| negative regulation of transcription factor import into nucleus | GO:0042992 | 17 | 0.223 | |
| lipid localization | GO:0010876 | 106 | 0.222 | |
| antibacterial humoral response | GO:0019731 | 24 | 0.220 | Fly |
| regulation of cytokine secretion | GO:0050707 | 57 | 0.218 | |
| pattern specification process | GO:0007389 | 43 | 0.215 | |
| positive regulation of intracellular protein transport | GO:0090316 | 76 | 0.214 | |
| cellular response to insulin stimulus | GO:0032869 | 41 | 0.209 | |
| interferon alpha production | GO:0032607 | 11 | 0.208 | Human |
| regulation of macrophage derived foam cell differentiation | GO:0010743 | 14 | 0.207 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.205 | |
| protein oligomerization | GO:0051259 | 173 | 0.203 | |
| regulation of protein secretion | GO:0050708 | 86 | 0.202 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.201 | |
| nuclear import | GO:0051170 | 106 | 0.201 | |
| response to muramyl dipeptide | GO:0032495 | 4 | 0.200 | |
| cellular response to oxygen levels | GO:0071453 | 55 | 0.199 | |
| regulation of cellular response to insulin stimulus | GO:1900076 | 17 | 0.197 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.196 | |
| positive regulation of interleukin 1 production | GO:0032732 | 14 | 0.195 | |
| organic anion transport | GO:0015711 | 103 | 0.193 | |
| cellular response to muramyl dipeptide | GO:0071225 | 3 | 0.193 | |
| positive regulation of cytokine secretion | GO:0050715 | 42 | 0.193 | |
| actin filament organization | GO:0007015 | 128 | 0.192 | |
| single organism cellular localization | GO:1902580 | 332 | 0.192 | |
| positive regulation of tumor necrosis factor production | GO:0032760 | 21 | 0.192 | |
| detection of chemical stimulus | GO:0009593 | 55 | 0.192 | |
| negative regulation of defense response | GO:0031348 | 47 | 0.191 | |
| antimicrobial humoral response | GO:0019730 | 26 | 0.190 | Fly |
| positive regulation of proteolysis | GO:0045862 | 142 | 0.188 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.186 | |
| response to uv | GO:0009411 | 73 | 0.185 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.184 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 119 | 0.181 | |
| regulation of protein stability | GO:0031647 | 87 | 0.181 | |
| nucleotide binding domain leucine rich repeat containing receptor signaling pathway | GO:0035872 | 5 | 0.179 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 56 | 0.178 | |
| peptide metabolic process | GO:0006518 | 51 | 0.177 | Fly |
| positive regulation of type i interferon mediated signaling pathway | GO:0060340 | 4 | 0.175 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 25 | 0.175 | Fly |
| regulation of cellular component size | GO:0032535 | 82 | 0.175 | |
| negative regulation of cytokine mediated signaling pathway | GO:0001960 | 22 | 0.174 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 69 | 0.172 | |
| positive regulation of protein transport | GO:0051222 | 135 | 0.172 | |
| regulation of response to cytokine stimulus | GO:0060759 | 46 | 0.171 | |
| organ morphogenesis | GO:0009887 | 147 | 0.168 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.168 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.165 | |
| response to hormone | GO:0009725 | 175 | 0.163 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.161 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.161 | |
| regulation of interleukin 1 secretion | GO:0050704 | 14 | 0.159 | |
| response to type i interferon | GO:0034340 | 14 | 0.158 | |
| alcohol metabolic process | GO:0006066 | 114 | 0.157 | |
| interferon gamma mediated signaling pathway | GO:0060333 | 7 | 0.156 | |
| carbon catabolite activation of transcription | GO:0045991 | 3 | 0.154 | |
| maintenance of protein location | GO:0045185 | 57 | 0.154 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.153 | Rat |
| negative regulation of interleukin 8 biosynthetic process | GO:0045415 | 3 | 0.150 | |
| jnk cascade | GO:0007254 | 80 | 0.149 | |
| positive regulation of cell activation | GO:0050867 | 81 | 0.148 | |
| regulation of body fluid levels | GO:0050878 | 99 | 0.148 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 37 | 0.146 | |
| dna repair | GO:0006281 | 198 | 0.144 | |
| cytoplasmic sequestering of nf kappab | GO:0007253 | 7 | 0.144 | |
| regulation of secretion | GO:0051046 | 194 | 0.144 | |
| peptidyl threonine phosphorylation | GO:0018107 | 41 | 0.142 | |
| negative regulation of stress activated mapk cascade | GO:0032873 | 19 | 0.141 | |
| regulation of response to wounding | GO:1903034 | 101 | 0.141 | |
| negative regulation of immune response | GO:0050777 | 40 | 0.140 | |
| wnt signaling pathway | GO:0016055 | 156 | 0.140 | |
| cellular response to starvation | GO:0009267 | 58 | 0.140 | |
| humoral immune response | GO:0006959 | 49 | 0.139 | Fly |
| insulin receptor signaling pathway | GO:0008286 | 23 | 0.138 | |
| t cell activation | GO:0042110 | 99 | 0.138 | |
| regulation of cell growth | GO:0001558 | 135 | 0.137 | |
| regulation of anatomical structure size | GO:0090066 | 101 | 0.137 | |
| inflammatory response | GO:0006954 | 79 | 0.136 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 88 | 0.136 | |
| positive regulation of multi organism process | GO:0043902 | 56 | 0.135 | Fly |
| positive regulation of secretion by cell | GO:1903532 | 108 | 0.134 | |
| positive regulation of intracellular transport | GO:0032388 | 104 | 0.132 | |
| regulation of response to interferon gamma | GO:0060330 | 7 | 0.130 | |
| negative regulation of kinase activity | GO:0033673 | 106 | 0.129 | |
| response to wounding | GO:0009611 | 168 | 0.129 | |
| chromatin modification | GO:0016568 | 298 | 0.129 | |
| cerebral cortex development | GO:0021987 | 10 | 0.128 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.128 | |
| negative regulation of interleukin 1 beta production | GO:0032691 | 6 | 0.126 | |
| cytokine production involved in immune response | GO:0002367 | 27 | 0.126 | |
| dicarboxylic acid metabolic process | GO:0043648 | 29 | 0.126 | |
| regulation of oocyte development | GO:0060281 | 1 | 0.125 | |
| response to inorganic substance | GO:0010035 | 127 | 0.125 | |
| secretion by cell | GO:0032940 | 226 | 0.123 | |
| odontogenesis | GO:0042476 | 25 | 0.122 | |
| monovalent inorganic cation transport | GO:0015672 | 128 | 0.121 | Mouse |
| stress activated protein kinase signaling cascade | GO:0031098 | 94 | 0.120 | |
| positive regulation of response to cytokine stimulus | GO:0060760 | 13 | 0.118 | |
| protein complex localization | GO:0031503 | 31 | 0.116 | |
| tissue morphogenesis | GO:0048729 | 96 | 0.116 | |
| regulation of transcription by galactose | GO:0000409 | 1 | 0.116 | |
| macrophage derived foam cell differentiation | GO:0010742 | 15 | 0.116 | |
| epithelial tube morphogenesis | GO:0060562 | 38 | 0.115 | |
| gastrulation with mouth forming second | GO:0001702 | 1 | 0.115 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.114 | |
| cytoplasmic sequestering of protein | GO:0051220 | 12 | 0.113 | |
| carbon catabolite activation of transcription from rna polymerase ii promoter | GO:0000436 | 3 | 0.113 | |
| regulation of cell activation | GO:0050865 | 125 | 0.113 | |
| negative regulation of interleukin 6 biosynthetic process | GO:0045409 | 3 | 0.112 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.111 | |
| blastoderm segmentation | GO:0007350 | 2 | 0.111 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.111 | |
| negative regulation of secretion by cell | GO:1903531 | 52 | 0.110 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.110 | Mouse |
| positive regulation of map kinase activity | GO:0043406 | 80 | 0.109 | |
| regulation of stress activated protein kinase signaling cascade | GO:0070302 | 85 | 0.108 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.108 | |
| protein secretion | GO:0009306 | 98 | 0.108 | |
| regulation of interleukin 1 beta production | GO:0032651 | 18 | 0.107 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 144 | 0.107 | |
| positive regulation of immune effector process | GO:0002699 | 40 | 0.107 | Fly |
| interleukin 17 production | GO:0032620 | 12 | 0.107 | |
| histone modification | GO:0016570 | 251 | 0.106 | |
| epithelium development | GO:0060429 | 227 | 0.106 | |
| signal transduction by p53 class mediator | GO:0072331 | 72 | 0.106 | |
| retina homeostasis | GO:0001895 | 42 | 0.104 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.104 | |
| interleukin 8 production | GO:0032637 | 51 | 0.103 | |
| vasculature development | GO:0001944 | 181 | 0.103 | |
| cellular response to reactive oxygen species | GO:0034614 | 50 | 0.103 | |
| regulation of lipid transport | GO:0032368 | 44 | 0.103 | |
| amide transport | GO:0042886 | 76 | 0.102 | |
| response to growth factor | GO:0070848 | 205 | 0.101 | |
| cellular response to hydrogen peroxide | GO:0070301 | 37 | 0.100 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.100 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 54 | 0.099 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.098 | |
| regulation of cellular amide metabolic process | GO:0034248 | 9 | 0.095 | Fly |
| response to peptidoglycan | GO:0032494 | 3 | 0.094 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.094 | |
| regulation of interleukin 1 production | GO:0032652 | 21 | 0.092 | |
| programmed necrotic cell death | GO:0097300 | 18 | 0.092 | |
| glycosylation | GO:0070085 | 71 | 0.092 | |
| cellular response to type i interferon | GO:0071357 | 12 | 0.092 | |
| defense response to fungus | GO:0050832 | 4 | 0.091 | |
| regulation of cytokine mediated signaling pathway | GO:0001959 | 41 | 0.091 | |
| response to alkaloid | GO:0043279 | 20 | 0.090 | |
| toll signaling pathway | GO:0008063 | 2 | 0.088 | |
| positive regulation of nf kappab import into nucleus | GO:0042346 | 13 | 0.088 | |
| positive regulation of secretion | GO:0051047 | 116 | 0.088 | |
| jak stat cascade | GO:0007259 | 46 | 0.087 | |
| response to hypoxia | GO:0001666 | 96 | 0.087 | |
| negative regulation of interleukin 1 beta secretion | GO:0050713 | 2 | 0.086 | |
| regulation of sterol transport | GO:0032371 | 21 | 0.086 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 57 | 0.086 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.086 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.085 | |
| pharynx development | GO:0060465 | 1 | 0.085 | |
| protein k33 linked ubiquitination | GO:1990390 | 1 | 0.085 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.084 | |
| single organism membrane organization | GO:0044802 | 268 | 0.084 | |
| positive regulation of interleukin 6 production | GO:0032755 | 21 | 0.083 | |
| negative regulation of cell size | GO:0045792 | 3 | 0.083 | |
| negative regulation of secretion | GO:0051048 | 58 | 0.083 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.083 | |
| response to interferon gamma | GO:0034341 | 39 | 0.082 | |
| response to thyroid hormone | GO:0097066 | 9 | 0.082 | |
| response to mechanical stimulus | GO:0009612 | 51 | 0.082 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.082 | |
| cell matrix adhesion | GO:0007160 | 85 | 0.082 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.081 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.081 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.081 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.081 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.081 | |
| urogenital system development | GO:0001655 | 65 | 0.081 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.081 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.080 | |
| cellular response to interleukin 1 | GO:0071347 | 35 | 0.080 | |
| cell projection organization | GO:0030030 | 252 | 0.080 | Rat |
| negative regulation of response to external stimulus | GO:0032102 | 83 | 0.080 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 8 | 0.080 | |
| mitotic cell cycle phase transition | GO:0044772 | 162 | 0.079 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.079 | |
| regulation of cellular component biogenesis | GO:0044087 | 281 | 0.079 | |
| regulation of vasculature development | GO:1901342 | 97 | 0.078 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.078 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.078 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.077 | |
| transmembrane transport | GO:0055085 | 399 | 0.077 | Mouse |
| digestive tract morphogenesis | GO:0048546 | 56 | 0.076 | |
| actin filament based process | GO:0030029 | 224 | 0.076 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.076 | |
| response to light stimulus | GO:0009416 | 87 | 0.076 | |
| positive regulation of endopeptidase activity | GO:0010950 | 84 | 0.075 | |
| carbon catabolite regulation of transcription from rna polymerase ii promoter | GO:0000429 | 3 | 0.075 | |
| mammary gland development | GO:0030879 | 17 | 0.075 | |
| regulation of angiogenesis | GO:0045765 | 92 | 0.074 | |
| endosomal transport | GO:0016197 | 129 | 0.074 | |
| vitamin metabolic process | GO:0006766 | 26 | 0.074 | |
| response to oxidative stress | GO:0006979 | 121 | 0.073 | |
| regulation of nik nf kappab signaling | GO:1901222 | 11 | 0.073 | |
| negative regulation of stress activated protein kinase signaling cascade | GO:0070303 | 19 | 0.073 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.072 | |
| regulation of protein processing | GO:0070613 | 150 | 0.072 | |
| cytokine secretion | GO:0050663 | 64 | 0.072 | |
| positive regulation of response to biotic stimulus | GO:0002833 | 18 | 0.072 | Fly |
| negative regulation of mapk cascade | GO:0043409 | 56 | 0.071 | |
| negative regulation of tor signaling | GO:0032007 | 11 | 0.070 | |
| negative regulation of cytokine biosynthetic process | GO:0042036 | 11 | 0.070 | |
| post embryonic development | GO:0009791 | 2 | 0.070 | |
| negative regulation of protein kinase activity | GO:0006469 | 98 | 0.069 | |
| regulation of ion transport | GO:0043269 | 189 | 0.069 | Mouse |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.068 | |
| oocyte differentiation | GO:0009994 | 2 | 0.068 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.068 | |
| lipid storage | GO:0019915 | 28 | 0.067 | |
| reproductive process | GO:0022414 | 106 | 0.067 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 158 | 0.067 | |
| regulation of actin filament length | GO:0030832 | 56 | 0.067 | |
| negative regulation of t cell apoptotic process | GO:0070233 | 4 | 0.067 | |
| histone acetylation | GO:0016573 | 93 | 0.067 | |
