IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

IMMT

inner membrane protein, mitochondrial

(Aliases: P89,MGC111146,P87/89,P87,HMP,DKFZp779P1653,PIG52)

Entrez: 10989
MIM: 600378
HGNC: 6047
Ensembl: ENSG00000132305
HPRD: 02658
UniProtKB: Q16891

Process Predictions
Disease Predictions

IMMT biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
oxidation reduction process	GO:0055114	396	0.796
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.737
nucleoside triphosphate metabolic process	GO:0009141	422	0.696
nucleoside phosphate biosynthetic process	GO:1901293	109	0.671
ribonucleotide biosynthetic process	GO:0009260	81	0.571
purine nucleotide biosynthetic process	GO:0006164	84	0.514
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.510
purine ribonucleoside metabolic process	GO:0046128	437	0.484
glycosyl compound biosynthetic process	GO:1901659	27	0.468
vesicle mediated transport	GO:0016192	371	0.443
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.441
ribose phosphate biosynthetic process	GO:0046390	82	0.396
nucleoside monophosphate metabolic process	GO:0009123	191	0.355
organonitrogen compound biosynthetic process	GO:1901566	200	0.353
generation of precursor metabolites and energy	GO:0006091	68	0.346
nucleotide biosynthetic process	GO:0009165	109	0.340
purine ribonucleotide biosynthetic process	GO:0009152	79	0.299
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.251
stem cell development	GO:0048864	69	0.246
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.241
atp metabolic process	GO:0046034	176	0.230
mesenchyme development	GO:0060485	59	0.204
carbohydrate derivative biosynthetic process	GO:1901137	207	0.201
regulation of nucleotide catabolic process	GO:0030811	205	0.196
defense response	GO:0006952	315	0.174
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.172
positive regulation of gtp catabolic process	GO:0033126	166	0.170
purine ribonucleoside biosynthetic process	GO:0046129	23	0.160
small molecule biosynthetic process	GO:0044283	157	0.149
epithelial to mesenchymal transition	GO:0001837	48	0.143
generation of neurons	GO:0048699	152	0.142
regulation of gtpase activity	GO:0043087	180	0.136
regulation of cell differentiation	GO:0045595	393	0.133
purine ribonucleotide catabolic process	GO:0009154	404	0.124
microtubule based process	GO:0007017	210	0.122
negative regulation of cell development	GO:0010721	48	0.119
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.119
ribonucleoside biosynthetic process	GO:0042455	25	0.115
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	16	0.115
organophosphate biosynthetic process	GO:0090407	163	0.114
determination of adult lifespan	GO:0008340	2	0.112
neuron differentiation	GO:0030182	138	0.108
protein polymerization	GO:0051258	71	0.100
dna conformation change	GO:0071103	113	0.099
energy derivation by oxidation of organic compounds	GO:0015980	43	0.099
negative regulation of developmental process	GO:0051093	247	0.098
purine containing compound biosynthetic process	GO:0072522	88	0.094
glycosyl compound catabolic process	GO:1901658	413	0.093
microtubule polymerization	GO:0046785	18	0.092
endomembrane system organization	GO:0010256	196	0.091
interspecies interaction between organisms	GO:0044419	156	0.090
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.087
negative regulation of multicellular organismal process	GO:0051241	317	0.086
secretion by cell	GO:0032940	226	0.083
stem cell differentiation	GO:0048863	93	0.083
purine nucleoside biosynthetic process	GO:0042451	23	0.077
positive regulation of hydrolase activity	GO:0051345	331	0.073
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	24	0.067
protein catabolic process	GO:0030163	325	0.065
cell division	GO:0051301	168	0.065
cell development	GO:0048468	328	0.065
positive regulation of nucleotide metabolic process	GO:0045981	230	0.064
nucleoside biosynthetic process	GO:0009163	26	0.064
oxidative phosphorylation	GO:0006119	10	0.063
small gtpase mediated signal transduction	GO:0007264	78	0.062
wnt signaling pathway	GO:0016055	156	0.061
mitochondrion organization	GO:0007005	156	0.060	Worm
negative regulation of cell differentiation	GO:0045596	171	0.060
cell type specific apoptotic process	GO:0097285	125	0.058
embryo development ending in birth or egg hatching	GO:0009792	34	0.058
ras protein signal transduction	GO:0007265	73	0.057
ribonucleotide catabolic process	GO:0009261	405	0.056
embryo development	GO:0009790	123	0.055
nucleoside catabolic process	GO:0009164	408	0.055
single organism cellular localization	GO:1902580	332	0.055
cellular component morphogenesis	GO:0032989	314	0.053	Worm
mesenchymal cell development	GO:0014031	50	0.052
cdc42 protein signal transduction	GO:0032488	4	0.051
lipid metabolic process	GO:0006629	381	0.051
positive regulation of immune system process	GO:0002684	283	0.049
mitotic cell cycle process	GO:1903047	286	0.049
neurogenesis	GO:0022008	169	0.049
purine containing compound catabolic process	GO:0072523	411	0.046
regulation of epithelial to mesenchymal transition	GO:0010717	37	0.046
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	11	0.046
intracellular protein transport	GO:0006886	270	0.045
biological adhesion	GO:0022610	331	0.044
cellular respiration	GO:0045333	21	0.043
regulation of protein transport	GO:0051223	213	0.041
neuron projection development	GO:0031175	106	0.040
regulation of cell motility	GO:2000145	299	0.040
microtubule nucleation	GO:0007020	6	0.039
response to inorganic substance	GO:0010035	127	0.039
mitotic cell cycle	GO:0000278	326	0.038
nucleoside phosphate catabolic process	GO:1901292	412	0.037
mesenchymal cell differentiation	GO:0048762	52	0.037
ion homeostasis	GO:0050801	230	0.037
cell morphogenesis	GO:0000902	296	0.037
cell adhesion	GO:0007155	325	0.036
defense response to other organism	GO:0098542	129	0.035
reactive oxygen species metabolic process	GO:0072593	75	0.035
microtubule cytoskeleton organization	GO:0000226	176	0.035
nucleotide catabolic process	GO:0009166	408	0.035
response to external biotic stimulus	GO:0043207	261	0.034
purine nucleoside catabolic process	GO:0006152	398	0.034
negative regulation of cellular component organization	GO:0051129	235	0.033
spermatid differentiation	GO:0048515	4	0.032
nucleoside triphosphate catabolic process	GO:0009143	394	0.032
posttranscriptional regulation of gene expression	GO:0010608	213	0.032
gtp metabolic process	GO:0046039	239	0.031
protein oligomerization	GO:0051259	173	0.031
cellular cation homeostasis	GO:0030003	163	0.031
multi organism cellular process	GO:0044764	156	0.031
ribonucleoside monophosphate biosynthetic process	GO:0009156	17	0.030
regulation of cell development	GO:0060284	161	0.030
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.030
viral life cycle	GO:0019058	132	0.030
regulation of cell morphogenesis involved in differentiation	GO:0010769	83	0.029
purine nucleoside monophosphate biosynthetic process	GO:0009127	16	0.029
double strand break repair	GO:0006302	101	0.029
regulation of protein stability	GO:0031647	87	0.029
respiratory electron transport chain	GO:0022904	7	0.028
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.028
negative regulation of programmed cell death	GO:0043069	321	0.028
regulation of intracellular protein transport	GO:0033157	123	0.028
regulation of membrane potential	GO:0042391	95	0.028
central nervous system development	GO:0007417	123	0.027
cellular component disassembly	GO:0022411	92	0.027
regulation of immune response	GO:0050776	201	0.027
cellular response to organic cyclic compound	GO:0071407	127	0.027
blastocyst development	GO:0001824	3	0.026
purine nucleotide catabolic process	GO:0006195	405	0.026
system process	GO:0003008	349	0.026
microtubule polymerization or depolymerization	GO:0031109	37	0.026
ossification	GO:0001503	121	0.026
response to other organism	GO:0051707	261	0.025
spindle organization	GO:0007051	53	0.025
regulation of purine nucleotide metabolic process	GO:1900542	264	0.025
primary mirna processing	GO:0031053	3	0.024
apoptotic mitochondrial changes	GO:0008637	57	0.024
nucleoside triphosphate biosynthetic process	GO:0009142	20	0.024
glycerophospholipid metabolic process	GO:0006650	84	0.024
amine metabolic process	GO:0009308	44	0.024
membrane organization	GO:0061024	292	0.024	Worm
neuron development	GO:0048666	113	0.024
gmp metabolic process	GO:0046037	4	0.023
organic acid transport	GO:0015849	65	0.023
cellular response to cytokine stimulus	GO:0071345	181	0.023
neuromuscular junction development	GO:0007528	3	0.023
regulation of binding	GO:0051098	111	0.023
regeneration	GO:0031099	4	0.023
purine ribonucleoside catabolic process	GO:0046130	398	0.023
post embryonic development	GO:0009791	2	0.023
regulation of purine nucleotide catabolic process	GO:0033121	205	0.022
regulation of small gtpase mediated signal transduction	GO:0051056	156	0.022
cellular macromolecule catabolic process	GO:0044265	380	0.022
response to biotic stimulus	GO:0009607	276	0.022
mitochondrial membrane organization	GO:0007006	40	0.022	Worm
tissue regeneration	GO:0042246	3	0.022
regulation of cell migration	GO:0030334	289	0.022
positive regulation of gtpase activity	GO:0043547	166	0.022
regulation of ras protein signal transduction	GO:0046578	155	0.022
negative regulation of epithelial to mesenchymal transition	GO:0010719	14	0.022
regulation of protein localization	GO:0032880	296	0.021
organelle fission	GO:0048285	149	0.021
innate immune response	GO:0045087	178	0.021
membrane fusion	GO:0061025	43	0.021
organophosphate catabolic process	GO:0046434	430	0.021
regulation of dna metabolic process	GO:0051052	153	0.020
lipid transport	GO:0006869	90	0.020
viral process	GO:0016032	146	0.020
positive regulation of cellular catabolic process	GO:0031331	284	0.020
atp synthesis coupled electron transport	GO:0042773	4	0.020
protein acylation	GO:0043543	138	0.020
regulation of establishment of protein localization	GO:0070201	242	0.020
spermatid development	GO:0007286	4	0.020
response to organic cyclic compound	GO:0014070	204	0.020
immune response	GO:0006955	307	0.020
regulation of system process	GO:0044057	101	0.020
rho protein signal transduction	GO:0007266	26	0.019
sperm egg recognition	GO:0035036	3	0.019
canonical wnt signaling pathway	GO:0060070	116	0.019
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.019
guanosine containing compound catabolic process	GO:1901069	239	0.019
ribonucleoside triphosphate biosynthetic process	GO:0009201	12	0.019
purine nucleoside triphosphate biosynthetic process	GO:0009145	11	0.019
cellular lipid metabolic process	GO:0044255	303	0.019
cellular ion homeostasis	GO:0006873	168	0.019
endosomal transport	GO:0016197	129	0.019
regulation of endopeptidase activity	GO:0052548	170	0.019
cellular response to oxidative stress	GO:0034599	85	0.019
symbiosis encompassing mutualism through parasitism	GO:0044403	156	0.019
regulation of mitochondrial membrane permeability	GO:0046902	25	0.018
centrosome organization	GO:0051297	58	0.018
protein stabilization	GO:0050821	64	0.018
protein secretion	GO:0009306	98	0.018
cellular response to growth factor stimulus	GO:0071363	197	0.017
single organism carbohydrate metabolic process	GO:0044723	193	0.017
lipid biosynthetic process	GO:0008610	177	0.016
cell morphogenesis involved in differentiation	GO:0000904	144	0.016
cation homeostasis	GO:0055080	189	0.016
regulation of cell adhesion	GO:0030155	166	0.016
establishment of protein localization to membrane	GO:0090150	121	0.016
positive regulation of purine nucleotide catabolic process	GO:0033123	185	0.016
positive regulation of intracellular protein transport	GO:0090316	76	0.016
eye photoreceptor cell differentiation	GO:0001754	2	0.016
protein acetylation	GO:0006473	116	0.016
single organism membrane organization	GO:0044802	268	0.015	Worm
cell projection morphogenesis	GO:0048858	129	0.015
cellular response to nitrogen compound	GO:1901699	144	0.015
lipid localization	GO:0010876	106	0.015
synaptic transmission	GO:0007268	61	0.015
protein localization to membrane	GO:0072657	160	0.015
photoreceptor cell differentiation	GO:0046530	2	0.015
chemotaxis	GO:0006935	157	0.015
positive regulation of nucleotide catabolic process	GO:0030813	185	0.015
translation	GO:0006412	132	0.014
extrinsic apoptotic signaling pathway via death domain receptors	GO:0008625	42	0.014
secretion	GO:0046903	254	0.014
regulation of viral process	GO:0050792	103	0.014
transmission of nerve impulse	GO:0019226	11	0.014
cellular amino acid metabolic process	GO:0006520	116	0.014
cytokine mediated signaling pathway	GO:0019221	109	0.014
monovalent inorganic cation transport	GO:0015672	128	0.014
nitrogen compound transport	GO:0071705	191	0.014
negative regulation of multi organism process	GO:0043901	92	0.014
positive regulation of developmental process	GO:0051094	314	0.014
positive regulation of nucleoside metabolic process	GO:0045979	186	0.013
modification dependent protein catabolic process	GO:0019941	209	0.013
response to oxygen containing compound	GO:1901700	369	0.013	Worm
guanosine containing compound metabolic process	GO:1901068	244	0.013
gland development	GO:0048732	48	0.013
cell projection organization	GO:0030030	252	0.013
brain development	GO:0007420	97	0.013
positive regulation of catabolic process	GO:0009896	310	0.013
regulation of stem cell differentiation	GO:2000736	56	0.013
regulation of cytokine production	GO:0001817	232	0.013
reproduction	GO:0000003	63	0.013
negative regulation of wnt signaling pathway	GO:0030178	69	0.013
behavior	GO:0007610	112	0.012
nucleoside monophosphate biosynthetic process	GO:0009124	19	0.012
endoplasmic reticulum organization	GO:0007029	20	0.012
positive regulation of cell development	GO:0010720	92	0.012
dna recombination	GO:0006310	77	0.012
endocytosis	GO:0006897	159	0.012
dna dependent dna replication	GO:0006261	44	0.012
regulation of dna binding	GO:0051101	37	0.012
regulation of mitochondrial membrane potential	GO:0051881	23	0.012
cellular protein complex assembly	GO:0043623	188	0.012
nuclear division	GO:0000280	128	0.012
anion transport	GO:0006820	161	0.012
cell cell signaling	GO:0007267	155	0.012
regulation of wnt signaling pathway	GO:0030111	123	0.012
gtp catabolic process	GO:0006184	237	0.012
cellular protein catabolic process	GO:0044257	261	0.012
osteoblast differentiation	GO:0001649	92	0.012
reproductive process	GO:0022414	106	0.012
single organismal cell cell adhesion	GO:0016337	148	0.011
negative regulation of neuron projection development	GO:0010977	15	0.011
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	50	0.011
negative regulation of protein transport	GO:0051224	75	0.011
response to bacterium	GO:0009617	144	0.011
negative regulation of cytoskeleton organization	GO:0051494	45	0.011
regulation of rho protein signal transduction	GO:0035023	79	0.011
regulation of protein kinase activity	GO:0045859	289	0.011
viral genome replication	GO:0019079	50	0.011
regulation of innate immune response	GO:0045088	97	0.011
cellular response to camp	GO:0071320	21	0.011
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.010
ribonucleoside catabolic process	GO:0042454	406	0.010
cell chemotaxis	GO:0060326	112	0.010
multi organism reproductive process	GO:0044703	54	0.010
multicellular organismal aging	GO:0010259	3	0.010
hemopoiesis	GO:0030097	180	0.010
regulation of ras gtpase activity	GO:0032318	128	0.010
regulation of cell cycle	GO:0051726	393	0.010

IMMT disease predictions

Disease	DO term ID	Size	Probability
cancer	DOID:162	167	0.100
disease of cellular proliferation	DOID:14566	174	0.100
organ system cancer	DOID:0050686	164	0.100
endocrine gland cancer	DOID:170	26	0.100
disease of metabolism	DOID:0014667	295	0.050
central nervous system disease	DOID:331	186	0.045
nervous system disease	DOID:863	431	0.045
neuropathy	DOID:870	52	0.033
inherited metabolic disorder	DOID:655	242	0.014
spinocerebellar degeneration	DOID:2478	27	0.013
neurodegenerative disease	DOID:1289	102	0.013

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