IMP: Integrative Multi-species Prediction

Homo sapiens

53 known processes

KIF5B

kinesin family member 5B

(Aliases: UKHC,KNS,KINH,KNS1)

MIM: 602809
HGNC: 6324
Ensembl: ENSG00000170759
HPRD: 07214
Entrez: 3799
UniProtKB: V9HW29
UniProtKB: Q6P164
UniProtKB: P33176

Process Predictions
Disease Predictions

KIF5B biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
microtubule cytoskeleton organization	GO:0000226	176	0.944	Worm Fly
microtubule based process	GO:0007017	210	0.933	Mouse Rat Worm Fly
establishment of organelle localization	GO:0051656	59	0.922	Mouse Rat Worm Fly
microtubule based movement	GO:0007018	32	0.909	Mouse Rat Fly
axon cargo transport	GO:0008088	2	0.851	Fly
membrane organization	GO:0061024	292	0.820
regulation of cellular component biogenesis	GO:0044087	281	0.713	Fly
synaptic transmission	GO:0007268	61	0.699	Mouse Worm
cellular macromolecular complex assembly	GO:0034622	324	0.693	Fly
regulation of cytoskeleton organization	GO:0051493	177	0.688
cell fate determination	GO:0001709	3	0.682
neural tube formation	GO:0001841	3	0.667
positive regulation of cellular component organization	GO:0051130	376	0.658
intracellular protein transport	GO:0006886	270	0.655	Fly
neurotransmitter secretion	GO:0007269	4	0.633
positive regulation of transport	GO:0051050	336	0.614
positive regulation of ras gtpase activity	GO:0032320	117	0.611
mitochondrion organization	GO:0007005	156	0.594	Fly
regulation of microtubule polymerization	GO:0031113	12	0.577
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.577
establishment of protein localization to organelle	GO:0072594	172	0.551
cytoplasmic transport	GO:0016482	379	0.547	Fly
regulation of cell morphogenesis	GO:0022604	153	0.544	Worm
establishment or maintenance of cytoskeleton polarity	GO:0030952	3	0.537	Fly
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.524
protein targeting to nucleus	GO:0044744	104	0.493
nucleus organization	GO:0006997	28	0.491
single organism membrane organization	GO:0044802	268	0.479
single organism nuclear import	GO:1902593	104	0.479
embryo development	GO:0009790	123	0.471	Worm Fly
regulation of cellular ketone metabolic process	GO:0010565	50	0.463
negative regulation of cell cycle	GO:0045786	193	0.451
small gtpase mediated signal transduction	GO:0007264	78	0.445
gtp metabolic process	GO:0046039	239	0.443
regulation of cell morphogenesis involved in differentiation	GO:0010769	83	0.438	Worm
cytokinesis	GO:0000910	96	0.434	Worm
negative regulation of cellular component organization	GO:0051129	235	0.431
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.419
signal transduction by phosphorylation	GO:0023014	297	0.414
cell projection assembly	GO:0030031	126	0.404
embryonic morphogenesis	GO:0048598	85	0.403
regulation of actin filament based process	GO:0032970	141	0.392
locomotory behavior	GO:0007626	1	0.391	Fly
purine containing compound catabolic process	GO:0072523	411	0.379
oocyte differentiation	GO:0009994	2	0.376	Fly
cell cell signaling	GO:0007267	155	0.376	Mouse Worm
neuron differentiation	GO:0030182	138	0.370	Worm Fly
glutamate metabolic process	GO:0006536	10	0.359
cellular protein catabolic process	GO:0044257	261	0.358
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.346
ras protein signal transduction	GO:0007265	73	0.346
positive regulation of wnt signaling pathway	GO:0030177	54	0.345
regulation of cell cycle	GO:0051726	393	0.343
oocyte development	GO:0048599	1	0.331	Fly
negative regulation of phosphate metabolic process	GO:0045936	267	0.331
single organism cellular localization	GO:1902580	332	0.328
endomembrane system organization	GO:0010256	196	0.324
nuclear division	GO:0000280	128	0.316	Worm
regulation of cellular component size	GO:0032535	82	0.314
cellular component disassembly	GO:0022411	92	0.312	Mouse Fly
mitotic cell cycle	GO:0000278	326	0.308
negative regulation of protein maturation	GO:1903318	142	0.307
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.305
organelle localization	GO:0051640	84	0.301	Mouse Rat Worm Fly
morphogenesis of embryonic epithelium	GO:0016331	4	0.294
cellular component morphogenesis	GO:0032989	314	0.283	Worm Fly
regulation of anatomical structure morphogenesis	GO:0022603	286	0.282	Worm
anterior posterior axis specification embryo	GO:0008595	2	0.282	Fly
oogenesis	GO:0048477	2	0.281	Fly
cellular macromolecule catabolic process	GO:0044265	380	0.272
positive regulation of organelle organization	GO:0010638	195	0.272
protein targeting	GO:0006605	187	0.270
cytoskeleton dependent cytokinesis	GO:0061640	22	0.263	Worm
ribonucleotide catabolic process	GO:0009261	405	0.261
autophagy	GO:0006914	88	0.259
regulation of protein maturation	GO:1903317	150	0.259
cellular response to dna damage stimulus	GO:0006974	379	0.257
tissue migration	GO:0090130	119	0.257
microtubule polymerization	GO:0046785	18	0.251	Fly
regulation of locomotion	GO:0040012	329	0.250
regulation of glutamine family amino acid metabolic process	GO:0000820	2	0.249
negative regulation of cellular protein metabolic process	GO:0032269	353	0.249
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	2	0.247	Fly
establishment or maintenance of epithelial cell apical basal polarity	GO:0045197	1	0.247
regulation of microtubule based process	GO:0032886	74	0.247
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.247
cellular homeostasis	GO:0019725	196	0.243
regulation of protein localization	GO:0032880	296	0.239
cell projection organization	GO:0030030	252	0.238	Worm Fly
regulation of wnt signaling pathway	GO:0030111	123	0.234
neuron projection development	GO:0031175	106	0.232	Worm Fly
mapk cascade	GO:0000165	288	0.232
establishment or maintenance of bipolar cell polarity	GO:0061245	2	0.230
regulation of proteasomal protein catabolic process	GO:0061136	87	0.229
negative regulation of epithelial cell proliferation	GO:0050680	48	0.228
cell division	GO:0051301	168	0.227	Worm
single organism carbohydrate metabolic process	GO:0044723	193	0.227
nucleoside catabolic process	GO:0009164	408	0.224
regulation of nucleotide metabolic process	GO:0006140	269	0.223
negative regulation of protein processing	GO:0010955	142	0.223
primary neural tube formation	GO:0014020	3	0.222
negative regulation of catabolic process	GO:0009895	104	0.221
regulation of cell motility	GO:2000145	299	0.220
regulation of protein transport	GO:0051223	213	0.219
regulation of cellular amine metabolic process	GO:0033238	11	0.219
protein polymerization	GO:0051258	71	0.216	Fly
regulation of vesicle mediated transport	GO:0060627	130	0.216
peptidyl serine phosphorylation	GO:0018105	101	0.215
embryonic epithelial tube formation	GO:0001838	4	0.209
actin filament based process	GO:0030029	224	0.207
tube morphogenesis	GO:0035239	95	0.201
signal release	GO:0023061	70	0.200
purine nucleoside catabolic process	GO:0006152	398	0.199
ribonucleoside catabolic process	GO:0042454	406	0.198
regulation of glucokinase activity	GO:0033131	2	0.197
regulation of synaptic plasticity	GO:0048167	3	0.196
regulation of protein polymerization	GO:0032271	63	0.196
negative regulation of protein metabolic process	GO:0051248	391	0.196
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.194
regulation of transferase activity	GO:0051338	355	0.194
regulation of gtp catabolic process	GO:0033124	180	0.194
nucleoside triphosphate metabolic process	GO:0009141	422	0.191
cellular chemical homeostasis	GO:0055082	180	0.190
protein depolymerization	GO:0051261	30	0.189
blastoderm segmentation	GO:0007350	2	0.178	Fly
glycosyl compound catabolic process	GO:1901658	413	0.178
protein processing	GO:0016485	226	0.177
synaptic vesicle transport	GO:0048489	5	0.177	Worm
regulation of cell projection organization	GO:0031344	107	0.177	Worm
generation of neurons	GO:0048699	152	0.176	Worm Fly
protein localization to organelle	GO:0033365	280	0.173
regulation of nervous system development	GO:0051960	88	0.171	Worm
nuclear import	GO:0051170	106	0.170
gtp catabolic process	GO:0006184	237	0.169
synaptic vesicle localization	GO:0097479	5	0.167	Worm
regulation of epithelial cell proliferation	GO:0050678	113	0.165
post embryonic development	GO:0009791	2	0.165
guanosine containing compound catabolic process	GO:1901069	239	0.163
regulation of protein processing	GO:0070613	150	0.163
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.163
cell adhesion	GO:0007155	325	0.160
establishment of vesicle localization	GO:0051650	23	0.158	Mouse Rat Worm
purine nucleotide catabolic process	GO:0006195	405	0.157
organelle assembly	GO:0070925	176	0.155
regulation of protein import into nucleus	GO:0042306	78	0.154
mitotic cell cycle phase transition	GO:0044772	162	0.153
protein modification by small protein removal	GO:0070646	92	0.153
axon development	GO:0061564	34	0.152	Worm Fly
nucleoside phosphate catabolic process	GO:1901292	412	0.152
cellular ketone metabolic process	GO:0042180	80	0.151
determination of adult lifespan	GO:0008340	2	0.151
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	91	0.150
cytoskeleton dependent intracellular transport	GO:0030705	21	0.149	Mouse Rat Fly
regulation of anatomical structure size	GO:0090066	101	0.148
regulation of cellular component movement	GO:0051270	334	0.145
negative regulation of proteolysis	GO:0045861	132	0.144
endocytosis	GO:0006897	159	0.144
regulation of cell migration	GO:0030334	289	0.143
negative regulation of apoptotic process	GO:0043066	316	0.141
negative regulation of catalytic activity	GO:0043086	335	0.141
ubiquitin dependent protein catabolic process	GO:0006511	206	0.141
regulation of kinase activity	GO:0043549	314	0.141
plasma membrane organization	GO:0007009	115	0.140
protein maturation	GO:0051604	233	0.139
purine ribonucleoside metabolic process	GO:0046128	437	0.138
protein deubiquitination	GO:0016579	79	0.136
cell morphogenesis	GO:0000902	296	0.134	Worm Fly
guanosine containing compound metabolic process	GO:1901068	244	0.134
negative regulation of cellular carbohydrate metabolic process	GO:0010677	14	0.134
negative regulation of phosphorylation	GO:0042326	174	0.133
regulation of protein targeting	GO:1903533	91	0.133
protein import	GO:0017038	130	0.131
positive regulation of locomotion	GO:0040017	186	0.131
engulfment of apoptotic cell	GO:0043652	2	0.131
nuclear transport	GO:0051169	179	0.128
positive regulation of apoptotic process	GO:0043065	246	0.127
organelle fission	GO:0048285	149	0.127	Worm
protein import into nucleus	GO:0006606	104	0.126
positive regulation of programmed cell death	GO:0043068	249	0.126
head development	GO:0060322	108	0.122
regulation of actin cytoskeleton organization	GO:0032956	116	0.122
regulation of purine nucleotide catabolic process	GO:0033121	205	0.121
positive regulation of transferase activity	GO:0051347	227	0.120
cellular amine metabolic process	GO:0044106	41	0.119
carbohydrate metabolic process	GO:0005975	207	0.119
positive regulation of gtpase activity	GO:0043547	166	0.118
cell development	GO:0048468	328	0.117	Worm Fly
regulation of rho protein signal transduction	GO:0035023	79	0.116
protein homooligomerization	GO:0051260	100	0.116
establishment or maintenance of cell polarity	GO:0007163	31	0.115	Worm Fly
negative regulation of hydrolase activity	GO:0051346	182	0.112
positive regulation of protein kinase activity	GO:0045860	190	0.112
negative regulation of transferase activity	GO:0051348	124	0.110
vesicle localization	GO:0051648	26	0.110	Mouse Rat Worm
response to starvation	GO:0042594	59	0.109
regulation of neuron differentiation	GO:0045664	70	0.109	Worm
negative regulation of programmed cell death	GO:0043069	321	0.108
modification dependent macromolecule catabolic process	GO:0043632	212	0.108
regulation of neuron projection development	GO:0010975	57	0.107	Worm
regulation of mapk cascade	GO:0043408	262	0.106
negative regulation of protein complex assembly	GO:0031333	43	0.105
positive regulation of nucleotide metabolic process	GO:0045981	230	0.105
negative regulation of kinase activity	GO:0033673	106	0.104
cell morphogenesis involved in differentiation	GO:0000904	144	0.103	Worm Fly
regulation of nucleocytoplasmic transport	GO:0046822	98	0.101
atp catabolic process	GO:0006200	157	0.101
negative regulation of phosphorus metabolic process	GO:0010563	267	0.100
nervous system development	GO:0007399	293	0.100	Worm Fly
growth	GO:0040007	202	0.100
regulation of protein complex assembly	GO:0043254	147	0.100
protein localization to nucleus	GO:0034504	136	0.100
negative regulation of protein phosphorylation	GO:0001933	140	0.099
negative regulation of cellular catabolic process	GO:0031330	83	0.099
positive regulation of cellular component biogenesis	GO:0044089	158	0.098
cell substrate adhesion	GO:0031589	132	0.097
negative regulation of multicellular organismal process	GO:0051241	317	0.096
regulation of ras protein signal transduction	GO:0046578	155	0.096
maintenance of location	GO:0051235	112	0.096
nucleocytoplasmic transport	GO:0006913	176	0.095
positive regulation of phosphorylation	GO:0042327	394	0.093
establishment of protein localization to plasma membrane	GO:0090002	68	0.093
cell cycle phase transition	GO:0044770	173	0.092
regulation of carbohydrate metabolic process	GO:0006109	54	0.090
regulation of cellular carbohydrate metabolic process	GO:0010675	47	0.090
nucleotide catabolic process	GO:0009166	408	0.088
neuron development	GO:0048666	113	0.088	Worm Fly
chromosome segregation	GO:0007059	114	0.088
somatic muscle development	GO:0007525	1	0.088
anterior posterior axis specification	GO:0009948	2	0.088	Fly
protein localization to plasma membrane	GO:0072659	93	0.088
maintenance of cell polarity	GO:0030011	2	0.087	Fly
positive regulation of intracellular transport	GO:0032388	104	0.087
enzyme linked receptor protein signaling pathway	GO:0007167	303	0.087
regulation of receptor mediated endocytosis	GO:0048259	32	0.085
secretion	GO:0046903	254	0.085
exocytosis	GO:0006887	71	0.084
maintenance of location in cell	GO:0051651	62	0.084
protein localization to membrane	GO:0072657	160	0.084
regulation of gtpase activity	GO:0043087	180	0.083
regulation of neurogenesis	GO:0050767	82	0.081	Worm
regulation of cellular protein catabolic process	GO:1903362	96	0.081
regulation of nucleoside metabolic process	GO:0009118	209	0.080
meiotic chromosome segregation	GO:0045132	4	0.080
purine ribonucleoside catabolic process	GO:0046130	398	0.080
organophosphate catabolic process	GO:0046434	430	0.080
positive regulation of kinase activity	GO:0033674	204	0.079
chemical homeostasis	GO:0048878	306	0.079
negative regulation of mitotic cell cycle	GO:0045930	102	0.079
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.078
tripartite regional subdivision	GO:0007351	2	0.077	Fly
modification dependent protein catabolic process	GO:0019941	209	0.077
rho protein signal transduction	GO:0007266	26	0.076
regulation of mitotic cell cycle phase transition	GO:1901990	118	0.076
female gamete generation	GO:0007292	2	0.073	Fly
vesicle mediated transport	GO:0016192	371	0.073	Worm
regulation of autophagy	GO:0010506	52	0.073
positive regulation of cellular amine metabolic process	GO:0033240	7	0.073
regulation of canonical wnt signaling pathway	GO:0060828	88	0.072
establishment of nucleus localization	GO:0040023	1	0.072	Fly
regulation of nucleotide catabolic process	GO:0030811	205	0.071
negative regulation of mitotic cell cycle phase transition	GO:1901991	85	0.071
mitotic cell cycle process	GO:1903047	286	0.071
lamellipodium organization	GO:0097581	30	0.071
brain development	GO:0007420	97	0.070
negative regulation of protein kinase activity	GO:0006469	98	0.070
spermatid development	GO:0007286	4	0.070
regulation of rho gtpase activity	GO:0032319	66	0.069
transmembrane transport	GO:0055085	399	0.069
negative regulation of protein modification process	GO:0031400	200	0.069
negative regulation of cell death	GO:0060548	345	0.069
regulation of cell adhesion	GO:0030155	166	0.068
establishment or maintenance of apical basal cell polarity	GO:0035088	2	0.068
mitotic spindle elongation	GO:0000022	4	0.068
establishment of protein localization to membrane	GO:0090150	121	0.068
positive regulation of gtp catabolic process	GO:0033126	166	0.067
digestive tract development	GO:0048565	75	0.067
secretion by cell	GO:0032940	226	0.067
regulation of small gtpase mediated signal transduction	GO:0051056	156	0.067
vasculature development	GO:0001944	181	0.067
positive regulation of cytoskeleton organization	GO:0051495	83	0.067
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.067
regulation of synaptic vesicle exocytosis	GO:2000300	2	0.066
regulation of intracellular protein transport	GO:0033157	123	0.066
microtubule polymerization or depolymerization	GO:0031109	37	0.066	Fly
regulation of ras gtpase activity	GO:0032318	128	0.066
tor signaling	GO:0031929	39	0.066
regulation of purine nucleotide metabolic process	GO:1900542	264	0.064
cellular protein complex disassembly	GO:0043624	36	0.064
cell cycle checkpoint	GO:0000075	117	0.063
insulin secretion	GO:0030073	39	0.063
cellular response to nutrient levels	GO:0031669	69	0.063
positive regulation of catabolic process	GO:0009896	310	0.063
axon extension	GO:0048675	13	0.062
negative regulation of rho gtpase activity	GO:0034259	4	0.062
photoreceptor cell differentiation	GO:0046530	2	0.061	Fly
macroautophagy	GO:0016236	39	0.061
regulation of microtubule cytoskeleton organization	GO:0070507	61	0.061
wound healing	GO:0042060	115	0.061
actin cytoskeleton organization	GO:0030036	207	0.061
cellular amino acid metabolic process	GO:0006520	116	0.060
neurological system process	GO:0050877	163	0.060
regulation of protein kinase activity	GO:0045859	289	0.059
positive regulation of nucleotide catabolic process	GO:0030813	185	0.059
positive regulation of cell motility	GO:2000147	177	0.059
positive regulation of meiotic cell cycle	GO:0051446	2	0.059
maintenance of protein location	GO:0045185	57	0.058
regulation of proteolysis	GO:0030162	293	0.058
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	18	0.058
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	71	0.057
cell junction organization	GO:0034330	79	0.057
cellular carbohydrate metabolic process	GO:0044262	84	0.056
meiotic nuclear division	GO:0007126	10	0.056	Worm
biological adhesion	GO:0022610	331	0.056
negative regulation of protein serine threonine kinase activity	GO:0071901	57	0.056
peptidyl serine modification	GO:0018209	106	0.055
positive regulation of rho gtpase activity	GO:0032321	56	0.055
gastrulation	GO:0007369	51	0.054
positive regulation of rac gtpase activity	GO:0032855	31	0.054
synaptic vesicle exocytosis	GO:0016079	3	0.054
digestive system development	GO:0055123	75	0.053
epithelial cell proliferation	GO:0050673	128	0.053
positive regulation of protein complex assembly	GO:0031334	86	0.053
regulation of dna metabolic process	GO:0051052	153	0.053
regulation of cytoplasmic transport	GO:1903649	149	0.053
inorganic ion transmembrane transport	GO:0098660	231	0.053
negative regulation of transport	GO:0051051	176	0.053
regulation of mitotic cell cycle	GO:0007346	189	0.052
regulation of protein serine threonine kinase activity	GO:0071900	179	0.052
wnt signaling pathway	GO:0016055	156	0.052
peptidyl tyrosine modification	GO:0018212	170	0.052
neuromuscular junction development	GO:0007528	3	0.052
amine metabolic process	GO:0009308	44	0.052
negative regulation of cell cycle process	GO:0010948	121	0.051
neurogenesis	GO:0022008	169	0.051	Worm Fly
negative regulation of microtubule polymerization or depolymerization	GO:0031111	17	0.051
regulation of odontogenesis	GO:0042481	4	0.051
positive regulation of neuron differentiation	GO:0045666	40	0.051
spindle elongation	GO:0051231	4	0.050
long term memory	GO:0007616	2	0.049
regulation of response to external stimulus	GO:0032101	222	0.049
cellular protein complex assembly	GO:0043623	188	0.049	Fly
nucleoside triphosphate catabolic process	GO:0009143	394	0.049
positive regulation of mapk cascade	GO:0043410	190	0.049
cell migration involved in gastrulation	GO:0042074	1	0.048
prostate gland development	GO:0030850	3	0.048
mitotic cell cycle checkpoint	GO:0007093	68	0.048
cellular response to endogenous stimulus	GO:0071495	336	0.048
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.047
positive regulation of canonical wnt signaling pathway	GO:0090263	33	0.046
protein oligomerization	GO:0051259	173	0.046
angiogenesis	GO:0001525	147	0.046
positive regulation of cell proliferation	GO:0008284	301	0.045
regulation of protein catabolic process	GO:0042176	155	0.045
cell fate commitment	GO:0045165	27	0.044
purine ribonucleotide catabolic process	GO:0009154	404	0.044
vacuole organization	GO:0007033	44	0.043
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.043
protein modification by small protein conjugation	GO:0032446	342	0.043
positive regulation of cell cycle	GO:0045787	140	0.042
regionalization	GO:0003002	29	0.042	Fly
response to oxygen containing compound	GO:1901700	369	0.042
cellular response to external stimulus	GO:0071496	111	0.041
reproduction	GO:0000003	63	0.041	Worm Fly
mitotic nuclear division	GO:0007067	119	0.040
nucleoside monophosphate catabolic process	GO:0009125	159	0.040
regulation of cell development	GO:0060284	161	0.040	Worm Fly
negative regulation of cytoskeleton organization	GO:0051494	45	0.040
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.039
negative regulation of organelle organization	GO:0010639	126	0.039
lipid metabolic process	GO:0006629	381	0.039
nucleus localization	GO:0051647	1	0.039	Fly
inorganic cation transmembrane transport	GO:0098662	194	0.038
intermediate filament based process	GO:0045103	17	0.038
establishment of cell polarity	GO:0030010	22	0.038	Worm
cellular response to extracellular stimulus	GO:0031668	72	0.038
regulation of cell cycle phase transition	GO:1901987	126	0.037
positive regulation of nucleoside metabolic process	GO:0045979	186	0.037
organelle fusion	GO:0048284	36	0.037
response to abiotic stimulus	GO:0009628	336	0.037
regulation of apoptotic signaling pathway	GO:2001233	175	0.037
reproductive process	GO:0022414	106	0.036	Fly
positive regulation of purine nucleotide catabolic process	GO:0033123	185	0.036
ion transmembrane transport	GO:0034220	338	0.036
cell projection morphogenesis	GO:0048858	129	0.036	Worm Fly
positive regulation of axon extension	GO:0045773	4	0.035
establishment of spindle orientation	GO:0051294	9	0.035	Worm
blood vessel development	GO:0001568	172	0.035
regulation of map kinase activity	GO:0043405	108	0.034
regulation of neurotransmitter secretion	GO:0046928	3	0.034
cognition	GO:0050890	43	0.034
regulation of neurotransmitter levels	GO:0001505	15	0.034
cell morphogenesis involved in neuron differentiation	GO:0048667	44	0.033	Worm Fly
positive regulation of protein serine threonine kinase activity	GO:0071902	119	0.033
central nervous system development	GO:0007417	123	0.033
canonical wnt signaling pathway involved in negative regulation of apoptotic process	GO:0044336	2	0.033
establishment of protein localization to mitochondrion	GO:0072655	22	0.033
regulation of intracellular transport	GO:0032386	195	0.033
somatic stem cell maintenance	GO:0035019	4	0.033
nuclear migration	GO:0007097	1	0.033
negative regulation of cell proliferation	GO:0008285	228	0.032
endosomal transport	GO:0016197	129	0.032
erk1 and erk2 cascade	GO:0070371	104	0.031
chromosome separation	GO:0051304	23	0.031
intermediate filament cytoskeleton organization	GO:0045104	17	0.031
negative regulation of carbohydrate metabolic process	GO:0045912	20	0.031
positive regulation of actin filament bundle assembly	GO:0032233	25	0.031
regulation of cell cycle process	GO:0010564	266	0.031
cation transmembrane transport	GO:0098655	238	0.031
tissue morphogenesis	GO:0048729	96	0.031
behavior	GO:0007610	112	0.030	Fly
spindle organization	GO:0007051	53	0.030
dna replication	GO:0006260	116	0.030
positive regulation of cell differentiation	GO:0045597	211	0.030
mitochondrial respiratory chain complex assembly	GO:0033108	23	0.030
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	50	0.030
negative regulation of cell cycle phase transition	GO:1901988	89	0.030
epithelial cell differentiation	GO:0030855	141	0.030
glutamine family amino acid metabolic process	GO:0009064	17	0.029
positive regulation of hydrolase activity	GO:0051345	331	0.029
neural tube closure	GO:0001843	3	0.029
developmental growth involved in morphogenesis	GO:0060560	23	0.029
regulation of cellular amino acid metabolic process	GO:0006521	6	0.029
phagocytosis	GO:0006909	42	0.029
regulation of chromosome segregation	GO:0051983	44	0.029
negative regulation of cellular protein catabolic process	GO:1903363	38	0.029
mitotic spindle organization	GO:0007052	27	0.029
regulation of cell projection assembly	GO:0060491	47	0.028
positive regulation of nucleocytoplasmic transport	GO:0046824	54	0.028
negative regulation of intracellular signal transduction	GO:1902532	183	0.028
metal ion transport	GO:0030001	272	0.028
endodermal cell fate specification	GO:0001714	4	0.028
regulation of establishment of protein localization	GO:0070201	242	0.028
regulation of endocytosis	GO:0030100	72	0.028
posttranscriptional regulation of gene expression	GO:0010608	213	0.028
receptor metabolic process	GO:0043112	81	0.027
negative regulation of cell motility	GO:2000146	104	0.027
defense response	GO:0006952	315	0.027
protein catabolic process	GO:0030163	325	0.027	Worm
meiosis i	GO:0007127	4	0.027
actin filament bundle assembly	GO:0051017	54	0.027
multicellular organismal aging	GO:0010259	3	0.027
developmental cell growth	GO:0048588	18	0.027
visual behavior	GO:0007632	2	0.027
cell cell junction organization	GO:0045216	69	0.027
regulation of axonogenesis	GO:0050770	16	0.027
response to extracellular stimulus	GO:0009991	85	0.026
response to peptide	GO:1901652	65	0.026
single organism cell adhesion	GO:0098602	179	0.026
cellular response to abiotic stimulus	GO:0071214	117	0.026
microtubule depolymerization	GO:0007019	18	0.026
chemotaxis	GO:0006935	157	0.026	Fly
regulation of protein localization to plasma membrane	GO:1903076	40	0.025
negative regulation of microtubule depolymerization	GO:0007026	12	0.025
hindbrain development	GO:0030902	3	0.025
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	181	0.025
cell part morphogenesis	GO:0032990	137	0.025	Worm Fly
negative regulation of developmental process	GO:0051093	247	0.025
maintenance of protein location in cell	GO:0032507	56	0.025
vacuolar transport	GO:0007034	34	0.025
single organism reproductive process	GO:0044702	98	0.025	Fly
vesicle organization	GO:0016050	62	0.025
positive regulation of cytoplasmic transport	GO:1903651	82	0.024
cellular response to oxygen containing compound	GO:1901701	276	0.024
apoptotic cell clearance	GO:0043277	12	0.024
microtubule anchoring	GO:0034453	24	0.024
cellular response to starvation	GO:0009267	58	0.024
positive regulation of protein phosphorylation	GO:0001934	313	0.024
negative regulation of peptidase activity	GO:0010466	91	0.023
multicellular organism reproduction	GO:0032504	42	0.023	Fly
response to other organism	GO:0051707	261	0.023
metal ion homeostasis	GO:0055065	169	0.023
actin filament bundle organization	GO:0061572	54	0.023
positive regulation of nervous system development	GO:0051962	54	0.023
cell growth	GO:0016049	160	0.023
regulation of binding	GO:0051098	111	0.023
stress fiber assembly	GO:0043149	40	0.023
response to growth factor	GO:0070848	205	0.023
sister chromatid segregation	GO:0000819	54	0.023
positive regulation of cell death	GO:0010942	263	0.023	Worm
actin filament organization	GO:0007015	128	0.023
negative regulation of apoptotic signaling pathway	GO:2001234	97	0.023
response to hormone	GO:0009725	175	0.022
proteasomal protein catabolic process	GO:0010498	176	0.022
regulation of exocytosis	GO:0017157	46	0.022
cilium morphogenesis	GO:0060271	75	0.022
tube development	GO:0035295	125	0.022
positive regulation of protein catabolic process	GO:0045732	75	0.022
negative regulation of protein complex disassembly	GO:0043242	20	0.022
positive regulation of cell growth	GO:0030307	48	0.022
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	36	0.022
metaphase anaphase transition of cell cycle	GO:0044784	21	0.022

KIF5B disease predictions

Disease	DO term ID	Size	Probability
organ system cancer	DOID:0050686	164	0.435
disease of cellular proliferation	DOID:14566	174	0.435
cancer	DOID:162	167	0.435
gastrointestinal system cancer	DOID:3119	52	0.022

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