IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

KPNA3

karyopherin alpha 3 (importin alpha 4)

(Aliases: IPOA4,SRP4,SRP1gamma,SRP1,hSRP1)

MIM: 601892
Ensembl: ENSG00000102753
HGNC: 6396
Entrez: 3839
HPRD: 03536
UniProtKB: O00505
UniProtKB: A0A024RDV7
UniProtKB: Q8IYQ9

Process Predictions
Disease Predictions

KPNA3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein catabolic process	GO:0030163	325	0.862
modification dependent protein catabolic process	GO:0019941	209	0.703
ubiquitin dependent protein catabolic process	GO:0006511	206	0.543
single organism cellular localization	GO:1902580	332	0.507	Human Worm Fly
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.456
proteasomal protein catabolic process	GO:0010498	176	0.456
multicellular organismal aging	GO:0010259	3	0.405
modification dependent macromolecule catabolic process	GO:0043632	212	0.374
cellular protein catabolic process	GO:0044257	261	0.372
protein modification by small protein removal	GO:0070646	92	0.362
nuclear division	GO:0000280	128	0.353	Worm
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	156	0.351
nls bearing protein import into nucleus	GO:0006607	2	0.323	Human
protein deubiquitination	GO:0016579	79	0.316
negative regulation of apoptotic process	GO:0043066	316	0.302
negative regulation of programmed cell death	GO:0043069	321	0.298
intracellular protein transport	GO:0006886	270	0.273	Human Worm Fly
protein localization to organelle	GO:0033365	280	0.271	Human Worm Fly
protein modification by small protein conjugation	GO:0032446	342	0.270
regulation of cell cycle	GO:0051726	393	0.265	Fly
negative regulation of cell cycle	GO:0045786	193	0.257	Fly
protein processing	GO:0016485	226	0.239
protein ubiquitination	GO:0016567	314	0.221
cellular macromolecule catabolic process	GO:0044265	380	0.207
nucleoside catabolic process	GO:0009164	408	0.203
cellular response to dna damage stimulus	GO:0006974	379	0.198	Fly
negative regulation of proteolysis	GO:0045861	132	0.193
cytoplasmic transport	GO:0016482	379	0.191	Human Worm Fly
cellular component morphogenesis	GO:0032989	314	0.186
chromosome segregation	GO:0007059	114	0.184
cellular macromolecular complex assembly	GO:0034622	324	0.174
negative regulation of cellular component organization	GO:0051129	235	0.173
negative regulation of cell death	GO:0060548	345	0.167
determination of adult lifespan	GO:0008340	2	0.165
regulation of protein maturation	GO:1903317	150	0.164
sister chromatid segregation	GO:0000819	54	0.161
mitotic cell cycle	GO:0000278	326	0.158	Fly
cellular protein complex assembly	GO:0043623	188	0.156
cell cycle checkpoint	GO:0000075	117	0.155	Fly
cell type specific apoptotic process	GO:0097285	125	0.152
rna processing	GO:0006396	255	0.145
nuclear transport	GO:0051169	179	0.144	Human Worm Fly
immune response	GO:0006955	307	0.143
establishment of protein localization to organelle	GO:0072594	172	0.141	Human Worm Fly
regulation of protein stability	GO:0031647	87	0.141
protein localization to nucleus	GO:0034504	136	0.140	Human Worm Fly
neuron differentiation	GO:0030182	138	0.133
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.132
enzyme linked receptor protein signaling pathway	GO:0007167	303	0.132
purine ribonucleoside metabolic process	GO:0046128	437	0.132
regulation of cell cycle process	GO:0010564	266	0.131	Fly
negative regulation of protein maturation	GO:1903318	142	0.126
female gamete generation	GO:0007292	2	0.126	Worm
regulation of nucleocytoplasmic transport	GO:0046822	98	0.123	Fly
positive regulation of cellular component organization	GO:0051130	376	0.122
posttranscriptional regulation of gene expression	GO:0010608	213	0.122	Worm
protein polyubiquitination	GO:0000209	110	0.120
negative regulation of mitotic cell cycle	GO:0045930	102	0.117	Fly
mitotic cell cycle process	GO:1903047	286	0.117	Fly
purine containing compound catabolic process	GO:0072523	411	0.113
negative regulation of protein processing	GO:0010955	142	0.112
regulation of protein catabolic process	GO:0042176	155	0.111
cell morphogenesis	GO:0000902	296	0.111
protein import	GO:0017038	130	0.110	Human Worm Fly
protein targeting	GO:0006605	187	0.109	Human Worm Fly
regulation of protein processing	GO:0070613	150	0.106
regulation of anatomical structure morphogenesis	GO:0022603	286	0.105
protein targeting to nucleus	GO:0044744	104	0.094	Human Worm Fly
microtubule cytoskeleton organization	GO:0000226	176	0.094
regulation of transferase activity	GO:0051338	355	0.094
glycosyl compound catabolic process	GO:1901658	413	0.093
regulation of mitotic cell cycle phase transition	GO:1901990	118	0.093	Fly
regulation of proteasomal protein catabolic process	GO:0061136	87	0.090
nervous system development	GO:0007399	293	0.085
autophagy	GO:0006914	88	0.083
negative regulation of mitotic cell cycle phase transition	GO:1901991	85	0.080	Fly
negative regulation of protein catabolic process	GO:0042177	59	0.078
purine nucleotide catabolic process	GO:0006195	405	0.078
defense response	GO:0006952	315	0.077
response to abiotic stimulus	GO:0009628	336	0.077	Fly
dna repair	GO:0006281	198	0.077
innate immune response	GO:0045087	178	0.076
negative regulation of catabolic process	GO:0009895	104	0.075
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.075
neuromuscular junction development	GO:0007528	3	0.073
ribonucleotide catabolic process	GO:0009261	405	0.073
monovalent inorganic cation transport	GO:0015672	128	0.071
amine metabolic process	GO:0009308	44	0.069
cellular response to cytokine stimulus	GO:0071345	181	0.069
regulation of protein targeting	GO:1903533	91	0.069	Fly
nucleocytoplasmic transport	GO:0006913	176	0.069	Human Worm Fly
post embryonic development	GO:0009791	2	0.069	Worm
regulation of growth	GO:0040008	165	0.068
system process	GO:0003008	349	0.068
protein maturation	GO:0051604	233	0.068
intrinsic apoptotic signaling pathway	GO:0097193	127	0.067
negative regulation of cell proliferation	GO:0008285	228	0.066
positive regulation of transport	GO:0051050	336	0.065	Fly
purine ribonucleotide catabolic process	GO:0009154	404	0.064
mitochondrion organization	GO:0007005	156	0.064
negative regulation of cellular protein metabolic process	GO:0032269	353	0.062
positive regulation of nfat protein import into nucleus	GO:0051533	3	0.061	Fly
protein k48 linked ubiquitination	GO:0070936	38	0.060
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.060
regulation of chromosome segregation	GO:0051983	44	0.059
negative regulation of catalytic activity	GO:0043086	335	0.059
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	71	0.059
histone deubiquitination	GO:0016578	16	0.058
cytokinesis	GO:0000910	96	0.057
nucleoside triphosphate catabolic process	GO:0009143	394	0.057
cation transport	GO:0006812	331	0.057
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	281	0.056
single organism membrane organization	GO:0044802	268	0.056
metal ion transport	GO:0030001	272	0.055
cellular amine metabolic process	GO:0044106	41	0.054
regulation of protein modification by small protein conjugation or removal	GO:1903320	107	0.053
mitotic sister chromatid segregation	GO:0000070	53	0.053
cell projection organization	GO:0030030	252	0.053
response to external biotic stimulus	GO:0043207	261	0.052
regulation of mitotic cell cycle	GO:0007346	189	0.051	Fly
regulation of cell morphogenesis involved in differentiation	GO:0010769	83	0.051
mitotic cell cycle phase transition	GO:0044772	162	0.051	Fly
negative regulation of protein metabolic process	GO:0051248	391	0.051
negative regulation of cell cycle process	GO:0010948	121	0.051	Fly
embryo development	GO:0009790	123	0.050	Worm
regulation of cell differentiation	GO:0045595	393	0.050
single organism nuclear import	GO:1902593	104	0.049	Human Worm Fly
organelle fission	GO:0048285	149	0.049	Worm
response to cytokine	GO:0034097	232	0.049
nucleoside phosphate catabolic process	GO:1901292	412	0.049
neurogenesis	GO:0022008	169	0.048
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.048
regulation of kinase activity	GO:0043549	314	0.048
regulation of cell morphogenesis	GO:0022604	153	0.048
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.048
positive regulation of cellular catabolic process	GO:0031331	284	0.048
regulation of protein localization	GO:0032880	296	0.047	Fly
regulation of microtubule based process	GO:0032886	74	0.047
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.046
neurological system process	GO:0050877	163	0.046
positive regulation of apoptotic process	GO:0043065	246	0.046
multicellular organismal reproductive process	GO:0048609	40	0.046	Worm
chordate embryonic development	GO:0043009	34	0.046
negative regulation of cellular protein catabolic process	GO:1903363	38	0.046
regulation of protein transport	GO:0051223	213	0.046	Fly
cellular homeostasis	GO:0019725	196	0.045
neuron development	GO:0048666	113	0.045
metaphase anaphase transition of cell cycle	GO:0044784	21	0.045
endocytosis	GO:0006897	159	0.045
negative regulation of growth	GO:0045926	97	0.045
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	91	0.044
regulation of intracellular transport	GO:0032386	195	0.044	Fly
regulation of response to external stimulus	GO:0032101	222	0.044
protein import into nucleus	GO:0006606	104	0.044	Human Worm Fly
negative regulation of proteasomal protein catabolic process	GO:1901799	32	0.043
negative regulation of phosphate metabolic process	GO:0045936	267	0.043
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.042
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.042
cellular ketone metabolic process	GO:0042180	80	0.042
nuclear import	GO:0051170	106	0.041	Human Worm Fly
reproductive process	GO:0022414	106	0.041	Worm
microtubule based process	GO:0007017	210	0.040
positive regulation of cell differentiation	GO:0045597	211	0.040
cell development	GO:0048468	328	0.040	Worm
locomotory behavior	GO:0007626	1	0.040
negative regulation of intracellular signal transduction	GO:1902532	183	0.039
regulation of translation	GO:0006417	89	0.039
signal transduction by phosphorylation	GO:0023014	297	0.039
generation of neurons	GO:0048699	152	0.038
morphogenesis of embryonic epithelium	GO:0016331	4	0.038
cell division	GO:0051301	168	0.038
response to other organism	GO:0051707	261	0.038
mitotic sister chromatid separation	GO:0051306	18	0.037
regulation of cytoplasmic transport	GO:1903649	149	0.037	Fly
endosomal transport	GO:0016197	129	0.037
regulation of proteolysis	GO:0030162	293	0.037
positive regulation of cell death	GO:0010942	263	0.037
regulation of establishment of protein localization	GO:0070201	242	0.036	Fly
regulation of cellular protein catabolic process	GO:1903362	96	0.036
photoreceptor cell differentiation	GO:0046530	2	0.036
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.035
cell morphogenesis involved in differentiation	GO:0000904	144	0.035
regulation of apoptotic signaling pathway	GO:2001233	175	0.035
nucleoside triphosphate metabolic process	GO:0009141	422	0.035
purine ribonucleoside catabolic process	GO:0046130	398	0.034
cellular amino acid metabolic process	GO:0006520	116	0.034
chromatin organization	GO:0006325	351	0.034
positive regulation of cellular component biogenesis	GO:0044089	158	0.033
positive regulation of organelle organization	GO:0010638	195	0.033
organelle assembly	GO:0070925	176	0.033
negative regulation of multicellular organismal process	GO:0051241	317	0.033
lipid transport	GO:0006869	90	0.032
cellular response to external stimulus	GO:0071496	111	0.032
membrane organization	GO:0061024	292	0.032
macromolecule methylation	GO:0043414	97	0.032
regulation of chromosome organization	GO:0033044	103	0.032
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	125	0.032
nucleoside monophosphate metabolic process	GO:0009123	191	0.032
oogenesis	GO:0048477	2	0.032	Worm
cell part morphogenesis	GO:0032990	137	0.031
neuron projection development	GO:0031175	106	0.031
positive regulation of meiotic cell cycle	GO:0051446	2	0.031
response to light stimulus	GO:0009416	87	0.031	Fly
response to nitrogen compound	GO:1901698	184	0.031
regulation of cellular component biogenesis	GO:0044087	281	0.031
positive regulation of dendrite morphogenesis	GO:0050775	3	0.031
cell projection morphogenesis	GO:0048858	129	0.031
small gtpase mediated signal transduction	GO:0007264	78	0.031
muscle structure development	GO:0061061	98	0.031
purine nucleoside catabolic process	GO:0006152	398	0.031
cellular lipid metabolic process	GO:0044255	303	0.031
response to radiation	GO:0009314	151	0.030	Fly
segmentation	GO:0035282	4	0.030
cell cell signaling	GO:0007267	155	0.030
vasculature development	GO:0001944	181	0.030
negative regulation of phosphorus metabolic process	GO:0010563	267	0.030
cell cycle phase transition	GO:0044770	173	0.030	Fly
developmental cell growth	GO:0048588	18	0.030
chromosome separation	GO:0051304	23	0.030
regulation of intracellular protein transport	GO:0033157	123	0.030	Fly
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.030
apoptotic signaling pathway	GO:0097190	268	0.030
memory	GO:0007613	3	0.029
oocyte differentiation	GO:0009994	2	0.029
atp catabolic process	GO:0006200	157	0.029
cell growth	GO:0016049	160	0.029
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.029
ribonucleoside catabolic process	GO:0042454	406	0.029
ribonucleoprotein complex subunit organization	GO:0071826	81	0.028
protein stabilization	GO:0050821	64	0.028
neuron projection morphogenesis	GO:0048812	50	0.028
regulation of cell growth	GO:0001558	135	0.028
actin filament based process	GO:0030029	224	0.027
negative regulation of cellular catabolic process	GO:0031330	83	0.027
regulation of cell projection organization	GO:0031344	107	0.027
regulation of protein localization to nucleus	GO:1900180	85	0.027	Fly
positive regulation of catabolic process	GO:0009896	310	0.027
negative regulation of cell cycle phase transition	GO:1901988	89	0.026	Fly
regulation of cell cycle phase transition	GO:1901987	126	0.026	Fly
regulation of cellular ketone metabolic process	GO:0010565	50	0.026
regulation of protein import into nucleus	GO:0042306	78	0.026	Fly
protein oligomerization	GO:0051259	173	0.026
epithelium development	GO:0060429	227	0.026
behavior	GO:0007610	112	0.026
regulation of cellular amino acid metabolic process	GO:0006521	6	0.025
positive regulation of developmental process	GO:0051094	314	0.025
purine ribonucleoside monophosphate catabolic process	GO:0009169	158	0.025
positive regulation of nucleocytoplasmic transport	GO:0046824	54	0.025	Fly
regulation of cellular amine metabolic process	GO:0033238	11	0.025
regulation of protein kinase activity	GO:0045859	289	0.025
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	181	0.025
dna replication	GO:0006260	116	0.024
regulation of mitotic sister chromatid separation	GO:0010965	27	0.024
lipid metabolic process	GO:0006629	381	0.024
establishment of rna localization	GO:0051236	39	0.024
negative regulation of phosphorylation	GO:0042326	174	0.024
atp metabolic process	GO:0046034	176	0.023
ribonucleoprotein complex assembly	GO:0022618	78	0.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	25	0.023
cerebral cortex radially oriented cell migration	GO:0021799	1	0.023
positive regulation of cell development	GO:0010720	92	0.023
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.023
vesicle mediated transport	GO:0016192	371	0.023
cell fate determination	GO:0001709	3	0.023
positive regulation of immune system process	GO:0002684	283	0.023
nucleotide catabolic process	GO:0009166	408	0.023
negative regulation of transferase activity	GO:0051348	124	0.022
translation	GO:0006412	132	0.022
chemical homeostasis	GO:0048878	306	0.022
regulation of i kappab kinase nf kappab signaling	GO:0043122	162	0.022
potassium ion transmembrane transport	GO:0071805	60	0.022
rho protein signal transduction	GO:0007266	26	0.022
protein homooligomerization	GO:0051260	100	0.022
response to organic cyclic compound	GO:0014070	204	0.022
histone modification	GO:0016570	251	0.022
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.022
intrinsic apoptotic signaling pathway in response to dna damage	GO:0008630	50	0.022
cell morphogenesis involved in neuron differentiation	GO:0048667	44	0.021
transmembrane transport	GO:0055085	399	0.021
regulation of cytoskeleton organization	GO:0051493	177	0.021
spindle checkpoint	GO:0031577	26	0.021
negative regulation of cell growth	GO:0030308	83	0.021
cellular response to oxygen containing compound	GO:1901701	276	0.021
regulation of dna metabolic process	GO:0051052	153	0.021
positive regulation of programmed cell death	GO:0043068	249	0.021
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	40	0.021
negative regulation of hydrolase activity	GO:0051346	182	0.021
ras protein signal transduction	GO:0007265	73	0.021
muscle tissue development	GO:0060537	62	0.020
metaphase anaphase transition of mitotic cell cycle	GO:0007091	21	0.020
cellular component disassembly	GO:0022411	92	0.020
ion homeostasis	GO:0050801	230	0.020
regulation of cellular response to stress	GO:0080135	244	0.020
response to growth factor	GO:0070848	205	0.020
positive regulation of cell projection organization	GO:0031346	64	0.020
response to oxidative stress	GO:0006979	121	0.020
mapk cascade	GO:0000165	288	0.020
chromatin modification	GO:0016568	298	0.020
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	35	0.020
central nervous system neuron axonogenesis	GO:0021955	3	0.020
mitotic nuclear division	GO:0007067	119	0.019
regulation of autophagy	GO:0010506	52	0.019
mitochondrion distribution	GO:0048311	3	0.019
reactive oxygen species metabolic process	GO:0072593	75	0.019
cellular response to extracellular stimulus	GO:0031668	72	0.019
regulation of cell development	GO:0060284	161	0.019
response to biotic stimulus	GO:0009607	276	0.019
oocyte development	GO:0048599	1	0.019
ribonucleoprotein complex biogenesis	GO:0022613	116	0.019
regulation of mitotic sister chromatid segregation	GO:0033047	27	0.019
cellular response to growth factor stimulus	GO:0071363	197	0.019
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	132	0.018
nuclear migration	GO:0007097	1	0.018
meiosis i	GO:0007127	4	0.018	Worm
positive regulation of cytoplasmic transport	GO:1903651	82	0.018	Fly
regulation of intrinsic apoptotic signaling pathway	GO:2001242	72	0.018
angiogenesis	GO:0001525	147	0.018
mitotic cell cycle checkpoint	GO:0007093	68	0.018	Fly
regulation of angiogenesis	GO:0045765	92	0.018
regulation of nervous system development	GO:0051960	88	0.018
phagocytosis	GO:0006909	42	0.018
covalent chromatin modification	GO:0016569	254	0.017
regulation of neuron differentiation	GO:0045664	70	0.017
growth	GO:0040007	202	0.017
dendrite development	GO:0016358	24	0.017
positive regulation of cell cycle	GO:0045787	140	0.017
dna integrity checkpoint	GO:0031570	71	0.017	Fly
associative learning	GO:0008306	1	0.017
negative regulation of mitotic sister chromatid separation	GO:2000816	17	0.017
cytokine mediated signaling pathway	GO:0019221	109	0.017
engulfment of apoptotic cell	GO:0043652	2	0.016
protein autophosphorylation	GO:0046777	123	0.016
positive regulation of protein transport	GO:0051222	135	0.016	Fly
rna splicing	GO:0008380	131	0.016
sensory perception	GO:0007600	103	0.016
regulation of peptidase activity	GO:0052547	180	0.016
positive regulation of protein phosphorylation	GO:0001934	313	0.016
regulation of sister chromatid segregation	GO:0033045	27	0.016
regulation of reactive oxygen species metabolic process	GO:2000377	41	0.016
positive regulation of autophagy	GO:0010508	24	0.016
axon extension	GO:0048675	13	0.016
response to uv	GO:0009411	73	0.016	Fly
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.016
single organism reproductive process	GO:0044702	98	0.016	Worm
g1 s transition of mitotic cell cycle	GO:0000082	78	0.016
regulation of vasculature development	GO:1901342	97	0.016
ribosomal protein import into nucleus	GO:0006610	2	0.015
positive regulation of cell proliferation	GO:0008284	301	0.015
nucleic acid phosphodiester bond hydrolysis	GO:0090305	102	0.015
response to extracellular stimulus	GO:0009991	85	0.015
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	50	0.015
establishment of nucleus localization	GO:0040023	1	0.015
nerve development	GO:0021675	4	0.015
positive regulation of cellular amine metabolic process	GO:0033240	7	0.015
rna phosphodiester bond hydrolysis	GO:0090501	35	0.015
nuclear transcribed mrna catabolic process no go decay	GO:0070966	2	0.015
anterior posterior axis specification embryo	GO:0008595	2	0.015
positive regulation of dna metabolic process	GO:0051054	73	0.015
positive regulation of secretion	GO:0051047	116	0.015
dephosphorylation	GO:0016311	209	0.015
negative regulation of kinase activity	GO:0033673	106	0.015
regulation of immune response	GO:0050776	201	0.015
divalent inorganic cation transport	GO:0072511	158	0.015
secretion	GO:0046903	254	0.015
glycerolipid metabolic process	GO:0046486	107	0.015
negative regulation of mitotic metaphase anaphase transition	GO:0045841	17	0.014
response to nutrient levels	GO:0031667	81	0.014
regulation of locomotion	GO:0040012	329	0.014
methylation	GO:0032259	106	0.014
chemotaxis	GO:0006935	157	0.014
negative regulation of nervous system development	GO:0051961	28	0.014
sensory perception of light stimulus	GO:0050953	35	0.014
multi organism reproductive process	GO:0044703	54	0.014	Worm
macromolecular complex disassembly	GO:0032984	60	0.014
positive regulation of protein import into nucleus	GO:0042307	46	0.014	Fly
nucleus localization	GO:0051647	1	0.014
positive regulation of protein kinase activity	GO:0045860	190	0.014
striated muscle tissue development	GO:0014706	59	0.014
reproductive structure development	GO:0048608	55	0.014
actin filament organization	GO:0007015	128	0.014
neuroblast proliferation	GO:0007405	4	0.014
positive regulation of nf kappab transcription factor activity	GO:0051092	81	0.013
response to oxygen containing compound	GO:1901700	369	0.013
carbohydrate metabolic process	GO:0005975	207	0.013
single organism carbohydrate metabolic process	GO:0044723	193	0.013
positive regulation of kinase activity	GO:0033674	204	0.013
ncrna metabolic process	GO:0034660	108	0.013
nuclear export	GO:0051168	69	0.013
protein localization to membrane	GO:0072657	160	0.013
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.013
phospholipid metabolic process	GO:0006644	99	0.013
regulation of protein serine threonine kinase activity	GO:0071900	179	0.013
positive regulation of phosphorylation	GO:0042327	394	0.013
regulation of intracellular steroid hormone receptor signaling pathway	GO:0033143	32	0.013
centrosome organization	GO:0051297	58	0.013
regulation of neural precursor cell proliferation	GO:2000177	4	0.013
negative regulation of chromosome segregation	GO:0051985	18	0.013
regulation of cellular component movement	GO:0051270	334	0.013
positive regulation of transferase activity	GO:0051347	227	0.013
maturation of ssu rrna	GO:0030490	3	0.013
muscle organ development	GO:0007517	56	0.013
response to virus	GO:0009615	126	0.013
protein polymerization	GO:0051258	71	0.013
cell cycle g1 s phase transition	GO:0044843	80	0.013
gtp catabolic process	GO:0006184	237	0.013
regulation of meiotic cell cycle	GO:0051445	4	0.013
regulation of secretion	GO:0051046	194	0.013
protein acetylation	GO:0006473	116	0.013
n terminal protein amino acid modification	GO:0031365	13	0.012
positive regulation of intracellular transport	GO:0032388	104	0.012	Fly
regulation of neurogenesis	GO:0050767	82	0.012
mrna metabolic process	GO:0016071	175	0.012
positive regulation of immune response	GO:0050778	159	0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000462	1	0.012
negative regulation of cell division	GO:0051782	31	0.012
positive regulation of ion transport	GO:0043270	87	0.012
ribosomal small subunit biogenesis	GO:0042274	13	0.012
regulation of endopeptidase activity	GO:0052548	170	0.012
embryo development ending in birth or egg hatching	GO:0009792	34	0.012	Worm
intrinsic apoptotic signaling pathway by p53 class mediator	GO:0072332	37	0.012
compound eye development	GO:0048749	1	0.012
negative regulation of peptidase activity	GO:0010466	91	0.012
development of primary sexual characteristics	GO:0045137	35	0.012
regulation of protein kinase b signaling	GO:0051896	61	0.012
positive regulation of protein serine threonine kinase activity	GO:0071902	119	0.012
adult locomotory behavior	GO:0008344	1	0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO:0042787	37	0.012
gonad development	GO:0008406	34	0.012
regulation of microtubule cytoskeleton organization	GO:0070507	61	0.012
response to fungus	GO:0009620	4	0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	90	0.012
response to wounding	GO:0009611	168	0.011
spermatid development	GO:0007286	4	0.011
digestive tract development	GO:0048565	75	0.011
positive regulation of innate immune response	GO:0045089	79	0.011
response to ionizing radiation	GO:0010212	65	0.011
positive regulation of protein localization to nucleus	GO:1900182	48	0.011	Fly
embryonic morphogenesis	GO:0048598	85	0.011
blood vessel morphogenesis	GO:0048514	162	0.011
negative regulation of developmental process	GO:0051093	247	0.011
tube morphogenesis	GO:0035239	95	0.011
cellular response to starvation	GO:0009267	58	0.011
nucleus organization	GO:0006997	28	0.011	Worm
lipid biosynthetic process	GO:0008610	177	0.011
myeloid cell differentiation	GO:0030099	117	0.011
biological adhesion	GO:0022610	331	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	158	0.011
cellular potassium ion transport	GO:0071804	60	0.011
regulation of cell division	GO:0051302	116	0.011
cell cycle arrest	GO:0007050	71	0.011
guanosine containing compound catabolic process	GO:1901069	239	0.011
cellular response to nutrient levels	GO:0031669	69	0.011
muscle cell differentiation	GO:0042692	63	0.011
regulation of cell adhesion	GO:0030155	166	0.011
regulation of body fluid levels	GO:0050878	99	0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	30	0.011
secretion by cell	GO:0032940	226	0.011
regulation of dendrite development	GO:0050773	18	0.010
positive regulation of proteolysis	GO:0045862	142	0.010
cation transmembrane transport	GO:0098655	238	0.010
blastoderm segmentation	GO:0007350	2	0.010
synaptic transmission	GO:0007268	61	0.010
regulation of innate immune response	GO:0045088	97	0.010
ossification	GO:0001503	121	0.010
inorganic ion transmembrane transport	GO:0098660	231	0.010
receptor mediated endocytosis	GO:0006898	84	0.010
tripartite regional subdivision	GO:0007351	2	0.010
neural tube formation	GO:0001841	3	0.010
protein homotetramerization	GO:0051289	28	0.010
protein kinase b signaling	GO:0043491	69	0.010
protein methylation	GO:0006479	74	0.010
stem cell division	GO:0017145	2	0.010

KPNA3 disease predictions

Disease	DO term ID	Size	Probability
organ system cancer	DOID:0050686	164	0.040
cancer	DOID:162	167	0.040
disease of cellular proliferation	DOID:14566	174	0.040
central nervous system disease	DOID:331	186	0.014
nervous system disease	DOID:863	431	0.014

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